Crosby, GB
David Crosby, Whittington GB
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20140069873 | Acidic Mine Water Remediation - A process for treating acidic mine drainage water to remove heavy metal ions is described in which acidic mine drainage water is contacted with direct process residue gel. | 03-13-2014 |
David Crosby, Oxford GB
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20130141692 | EYEGLASSES AND MEANS FOR THEIR ADJUSTMENT - Eyeglasses which comprise a pair of optical plates for each eye. Each of the optical plates is made up of a front plate and a rear plate and a return and hinge mechanism links the optical plates of each pair with one another. An adjustment mechanism facilitates relative movement of the optical plates, of each pair, in a plane substantially perpendicular to a viewing direction of the eyeglasses. The return and hinge mechanism and the adjustment mechanism are decoupled. | 06-06-2013 |
20140211148 | ADJUSTABLE REFRACTIVE OPTICAL DEVICE - A method of making a lens having adjustable optical power is disclosed. The lens is adjustable by relative lateral translation of at least two lens elements. The method may comprise providing a function yielding optical properties of the lens from starting geometries for the lens elements; refining the function to approximate required gaze angle optical performance over a range of said lateral translation; and using the refined function to derive geometries for making the lens elements. The function may comprise first and second functional parts respectively for the lens elements, and the method comprises using the function to derive geometries for making the lens elements, wherein the function relates optical path difference to a position across the lens elements, and the rate of change of curvature of the first functional part with position is different to the rate of change of curvature of the second functional part with position. There is also disclosed a lens having adjustable optical power. The lens is adjustable by relative lateral translation of at least two lens elements. The adjustable lens may be used for corrective eyeglasses. | 07-31-2014 |
David Nicholas Crosby, Oxford GB
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20130141690 | REFRACTIVE EYEWEAR - An optical apparatus ( | 06-06-2013 |
20140253873 | METHOD OF FORMING VARIABLE FOCUS EYEWEAR - A method of forming a support member to a flexible membrane is provided by the present disclosure. In one form, the method includes placing the flexible membrane onto an outer periphery of a fixed tool, translating a movable tool towards the fixed tool, and engaging the flexible membrane such that the flexible membrane is deformed and placed into tension. A molten resin is then injected into a support ring molding cavity, and the resin is allowed to cool such that the support ring is secured to the tensioned flexible membrane. The movable tool is then translated away from the fixed tool to eject a flexible membrane and support ring assembly. | 09-11-2014 |
20150331257 | METHOD OF FORMING VARIABLE FOCUS EYEWEAR - A method of forming a support member to a flexible membrane is provided by the present disclosure. In one form, the method includes placing the flexible membrane onto an outer periphery of a fixed tool, translating a movable tool towards the fixed tool, and engaging the flexible membrane such that the flexible membrane is deformed and placed into tension. A molten resin is then injected into a support ring molding cavity, and the resin is allowed to cool such that the support ring is secured to the tensioned flexible membrane. The movable tool is then translated away from the fixed tool to eject a flexible membrane and support ring assembly. | 11-19-2015 |
Gary Crosby, Worcestershire GB
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20140306467 | Retention Arrangement - A retention arrangement for releasably securing a closure against a fixed body is provided. The retention arrangement includes a housing defining a mouth configured to receive a striker and defining a longitudinal axis, and at least one retention element configured to selectively retain said striker within the mouth, and movable between an open position and a closed position. The retention element is resiliently biased towards the closed position. The retention element is configured to open upon displacement due to said striker along the longitudinal axis in a first direction, and to close upon complete insertion of said striker within the mouth. The retention element is configured for rotation about at least two non-parallel axes so as to direct said striker towards the mouth. | 10-16-2014 |
Gary Thomas Crosby, Ware, Hertfordshire GB
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20150328044 | Guide Device For A Liquid Dispenser - A guide device for assisting the application of a liquid from a dispenser to the eye of a subject has a mount to hold the liquid dispenser in the guide device, a rest to align the guide device with the subject head, and an indicator, selectively visible to indicate when the guide device is tilted at or beyond a minimum guide angle. Preferably, the indicator is selectively visible to indicate when the guide device is tilted at, or between, the minimum guide angle and a maximum guide angle. | 11-19-2015 |
Gary Thomas Crosby, Hertfordshire GB
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20090090787 | Counter for Use with a Medicament Dispenser - A dose counter for use with a medicament dispenser which comprises a ratchet; a first count wheel arranged to rotate about a first axis of rotation, the first count wheel including one or more ratchet drive receipt elements arranged thereon for receipt of drive from the ratchet to rotate the first count wheel about the first axis of rotation; a second count wheel arranged to rotate about the first axis of rotation, the second count wheel including a set of teeth arranged annularly thereon; and a kick wheel arranged to rotate about a second axis of rotation offset from the first axis of rotation, the kick wheel including a set of kick teeth arranged annularly thereon and in meshed relationship with the teeth of the second count wheel such that rotary motion of the kick wheel results in rotary motion of the second count wheel is described. | 04-09-2009 |
20100218759 | DRUG DISPENSER - There is provided a drug dispenser device comprising a housing; extending from the housing, an outlet for insertion into a body cavity of a patient; provided to the housing and moveable with respect thereto, a drug discharge device having a longitudinal axis and comprising a container for storing a drug formulation to be dispensed, a discharge mechanism and a discharge channel from the container for discharge of the drug formulation to the outlet; connecting to the drug discharge device, a container collar; connecting to the container collar and moveable with respect thereto along the longitudinal axis of the drug discharge device, a transfer element, the transfer element including an actuating portion; provided to the housing, at least one finger operable member moveable to apply a force to the actuating portion of the transfer element to move the transfer element along the longitudinal axis in a first direction; linking the container collar with the transfer element, a biasing mechanism to store biasing energy on moving the transfer element along the longitudinal axis in the first direction; and provided to the container collar, a pre-load mechanism to prevent transfer of the biasing energy to the container collar to move the drug discharge device along the longitudinal axis in the first direction to actuate the discharge mechanism until a pre-determined threshold force is overcome. | 09-02-2010 |
20100224185 | ACTUATOR FOR AN INHALER - An actuator for an inhaler for delivering medicament by inhalation, comprising: a housing for receiving a canister which comprises a body which includes a base and a head and defines a chamber containing medicament, and a valve stem which extends from the body and from which medicament is in use delivered on actuation of the canister; an outlet through which a user in use inhales; and a nozzle assembly which provides for delivery of medicament through the outlet, wherein the nozzle assembly comprises a nozzle block which receives the valve stem of the canister and, as a separately-formed component, a nozzle outlet which is fluidly connected to the nozzle block and includes an outlet orifice from which medicament is in use delivered. | 09-09-2010 |
20100275909 | ACTUATOR FOR AN INHALER - An actuator for an inhaler for delivering drug by inhalation, comprising: a housing for receiving a canister which comprises a body which includes a base and a head and defines a chamber for containing drug, and a valve stem which extends from the body and from which drug is in use delivered on actuation of the canister; an outlet through which a user in use inhales; and a nozzle which provides for delivery of drug through the outlet; wherein at least a rear section of the outlet has an increasing internal dimension in a direction away from the nozzle. | 11-04-2010 |
20110061646 | DRUG DISPENSER - One aspect provides a drug dispenser device comprising a housing; extending from the housing, an outlet for insertion into a body cavity of a patient; provided to the housing and moveable with respect thereto, a drug discharge device having a longitudinal axis and comprising a container for storing a drug formulation to be dispensed, a discharge mechanism and a discharge channel from the container for discharge of the drug formulation to the outlet; connecting to the container, a container collar connected to the discharge device; connecting to the container collar and moveable with respect thereto along the longitudinal axis of the drug discharge device; connecting to the container collar and moveable with respect thereto along the longitudinal axis of the drug discharge device, a transfer element including an actuating portion; provided to the housing, at least one finger operable member moveable to apply an actuating force to the actuating portion of the transfer clement to move the transfer element from an initial position along the longitudinal axis in a first direction; provided to the container collar, a pre-load mechanism to prevent transfer of the actuating force to the container collar to move the drug discharge device along the longitudinal axis in the first direction to actuate the discharge mechanism until a pre-determined threshold force is overcome; and connecting the container collar with the transfer element, a biasing return mechanism acting to bias the transfer element along the longitudinal axis in a second direction to return the transfer element to its initial position. | 03-17-2011 |
20110259323 | ACTUATOR FOR AN INHALER - An actuator for an inhaler for delivering drug by inhalation, comprising: a housing for receiving a canister which comprises a body which includes a base and a head and defines a chamber for containing drug, and a valve stem which extends from the body and from which drug is in use delivered on actuation of the canister; and an outlet through which a user in use inhales, wherein the outlet has a substantially closed rear section which partitions the outlet from the housing, such that, on inhalation through the outlet, an air flow is drawn substantially only from an outer peripheral surface of the outlet. | 10-27-2011 |
Gary Thomas Crosby, Herfordshire GB
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20100218760 | ACTUATOR FOR AN INHALER - An actuator for an inhaler for delivering drug by inhalation, comprising: a housing for receiving a canister which comprises a body which includes a base and a head and defines a chamber for containing drug, and a valve stem which extends from the body and from which drug is in use delivered on actuation of the canister; an outlet through which a user in use inhales; and a nozzle which provides for delivery of drug through the outlet; wherein the outlet includes at least one air flow path which provides for a substantially annular air flow at an inner peripheral surface of the outlet on inhalation by the user through the outlet, such as to provide a sheathing air flow to an aerosol spray when delivered from the nozzle. | 09-02-2010 |
Gary Thomas Crosby, Ware GB
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20150209178 | LIQUID DROPLET DISPENSER - A dispenser for the delivery of a droplet of a liquid comprises a housing which defines an outlet orifice, a tip seal, biased against the housing to seal the outlet orifice, and a dosing pump for pumping a liquid to the outlet nozzle. The dispenser further comprises an actuation pump configured to provide a hydraulic opening force to the tip seal for opening of the outlet orifice. Preferably the actuation pump is configured to operate at a higher pressure than the dosing pump. | 07-30-2015 |
Helen Margaret Crosby, Watford GB
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20130237304 | SYSTEMS AND METHODS FOR SECOND CHANCE GAMES - Systems and methods for second chance games are disclosed. According to one particular embodiment, a computer-implemented method may comprise: receiving information of a first chance game established on a first medium, wherein a play of the first chance game provides an access mechanism for a second chance game; establishing the second chance game on a second medium based at least in part on the information of the first chance game; predetermining, by at least one processor, an outcome of the second chance game by a associating predetermined results with a plurality of game sessions; receiving from a player a request to access the second chance game submitted based on the access mechanism; assigning to the player one of the plurality of game sessions having a predetermined result; and facilitating the player's play of the second chance game to reveal to the player the predetermined result of the assigned game session. | 09-12-2013 |
Ian Crosby, Wirral GB
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20100317004 | PROBES - The present invention relates to probes, methods and apparatus for the detection of the presence or absence of non-contiguous cis-located nucleic acid sequences which are characteristic of alleles including those relating to the human leukocyte antigen (HLA) which is of interest in the field of human transplantation and disease. | 12-16-2010 |
James Crosby, Cambridge GB
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20150355900 | METHOD AND DEVICE FOR UPDATING SOFTWARE EXECUTED FROM NON-VOLATILE MEMORY - A data processing device | 12-10-2015 |
Jeffrey N. Crosby, Nuneaton GB
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20100101962 | Immersion method - A composition and method for inhibiting corrosion is disclosed. Metals and metal alloys are treated with compositions which contain inorganic and organic acids that prevent oxide formation on the metals and metal alloys. | 04-29-2010 |
John Crosby, Altrincham GB
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20080221322 | CHEMICAL PROCESS - The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-fluoro-2-methylindol-5-yloxy)-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline. | 09-11-2008 |
John Crosby, Macclesfield GB
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20110257395 | Chemical Process - The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-fluoro-2-methylindol-5-yloxy)-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline. | 10-20-2011 |
Paul Crosby, London GB
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20110094619 | SYSTEM FOR DISPENSING A FLUID IN NON-CONTROLLED ENVIRONMENTS - The present invention provides a dispenser cassette ( | 04-28-2011 |
Phillip John Crosby, Derby GB
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20160001360 | COMPONENT CASTING - A method includes forming a mould, the mould having at least one mould portion defining the shape of an element to be removed from the component in a subsequent manufacturing step and having a reduced cross-sectional area. The at least one mould portion includes at least one recess which further reduces the cross sectional area of the cavity and increases the surface area of the at least one mould portion or the at least one mould portion includes a plurality of projections which increase the surface area of the least one mould portion thereby increasing radiative heat loss from said at least one mould portion during said process. A mould for use in this method and a turbine blade formed using this method, are also provided | 01-07-2016 |
Stuart Richard Crosby, Cambridge GB
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20110124626 | BENZAZEPINE DERIVATIVES AND THEIR USE AS HISTAMINE H3 ANTAGONISTS - A compound having the formula (1) wherein: R1 is a group selected from C | 05-26-2011 |
Stuart Richard Crosby, Cambridgeshire GB
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20160000784 | PYRIMIDINE COMPOUNDS USEFUL IN THE TREATMENT OF DISEASES MEDIATED BY IKKE AND/OR TBK1 MECHANISMS - Compounds of the general formula (I) and salts thereof are useful in the treatment of diseases associated with aberrant activity of the protein kinases IKKε and/or TBK-1 in which one of V and W is N, and the other of V and W is C—H; and R | 01-07-2016 |