Patent application number | Description | Published |
20110253330 | FIRE AND SMOKE RETARDANT COMPOSITE MATERIALS - Flame retardant composite materials are provided which include at least one first paper which comprises carbon nanofibers and graphite oxide particles. The composite materials may further include at least one second paper which comprises carbon nanofibers. The composites may further include one or more structural material layers sandwiched between the first and second papers. Occupant structures are also provided with fire and smoke retardant surfaces composed of carbon nanofibers/graphite oxide particles papers at least partially surrounding occupants of the occupant structures. | 10-20-2011 |
20120009381 | CARBON NANOTUBE HONEYCOMB AND METHODS OF MAKING AND USE THEREOF - Materials that have a honeycomb structure are provided that are formed, at least in part, from carbon nanotube sheets. Methods are also provided for making these materials, including the expansion method, in which an adhesive is applied to carbon nanotube sheets, which are then stacked and expanded to form the honeycomb structure, or a corrugated method, in which an adhesive is applied to corrugated sheets, which are then stacked to form the honeycomb structure. | 01-12-2012 |
20120085970 | Composite Materials Reinforced with Carbon Nanotube Yarns - Composite materials are provided that include one or more CNT yarns embedded in a matrix material. The composite materials may be transparent. Methods for making the composite materials are also provided. The composite materials may be made by arranging at least one CNT yarn into a desired pattern and embedding the at least one CNT yarn into a matrix material. | 04-12-2012 |
20120123061 | Composite Materials and Method for Making High-Performance Carbon Nanotube Reinforced Polymer Composites - Nanocomposite materials and methods of making composite materials reinforced with carbon nanotubes are disclosed. The composite material includes an array of functionalized and aligned carbon nanotubes having a degree of functionalization of about 1% to about 10%; and a polymeric matrix material bonded to the array of functionalized and aligned carbon nanotubes. | 05-17-2012 |
20120222812 | Fire Retardant Materials and Methods - Fire retardant materials arc provided that contain carbon nanotubes and particles capable of endothermically reacting when exposed to elevated temperatures. The carbon nanotubes may be a buckypaper. Methods also are provided for making a fire retardant material and for improving the fire retardation capabilities of a material. | 09-06-2012 |
20140041819 | FIRE AND SMOKE RETARDANT COMPOSITE MATERIALS - Flame retardant composite materials are provided which include at least one first paper which comprises carbon nanofibers and graphite oxide particles. The composite materials may further include at least one second paper which comprises carbon nanofibers. The composites may further include one or more structural material layers sandwiched between the first and second papers. Occupant structures are also provided with fire and smoke retardant surfaces composed of carbon nanofibers/graphite oxide particles papers at least partially surrounding occupants of the occupant structures. | 02-13-2014 |
20140096886 | Fire Retardant Materials and Methods - Fire retardant materials are provided that contain carbon nanotubes and particles capable of endothermically reacting when exposed to elevated temperatures. The carbon nanotubes may be a buckypaper. Methods also are provided for making a fire retardant material and for improving the fire retardation capabilities of a material. | 04-10-2014 |
Patent application number | Description | Published |
20130262091 | AUTOMATED EXTRACTION OF BIO-ENTITY RELATIONSHIPS FROM LITERATURE - Automated, standardized and accurate extraction of relationships within text. Automatic extraction of such relationships/information allows the information to be stored in structured form so that it can be easily and accurately retrieved when needed. Such information can be used to build online search engines for highly specific and accurate information retrieval. The current invention discloses a novel approach to extract such information from raw text based on natural language processing (NLP) and graph theoretic algorithm. The novel method can be applied, for example, to extract protein-protein relationships in biomedical literature. The method can be easily extended to extract other biological relationships between biological terms such as proteins, genes, pathways, diseases and drugs. The method can also be applied to other information domains to extract other relationships. | 10-03-2013 |
20130339005 | Automated Extraction of Bio-Entity Relationships from Literature - Automated, standardized and accurate extraction of relationships within text. Automatic extraction of such relationships/information allows the information to be stored in structured form so that it can be easily and accurately retrieved when needed. Such information can be used to build online search engines for highly specific and accurate information retrieval. The current invention discloses a novel approach to extract such information from raw text based on natural language processing (NLP) and graph theoretic algorithm. The novel method can be applied, for example, to extract protein-protein relationships in biomedical literature. The method can be easily extended to extract other biological relationships between biological terms such as proteins, genes, pathways, diseases and drugs. The method can also be applied to other information domains to extract other relationships. | 12-19-2013 |
20140149048 | FINGERPRINT FOR CELL IDENTITY AND PLURIPOTENCY - A method for determining a replication timing footprint comprises the following steps: (a) selecting a set of chosen regions of the replication timing profile of a chromosome of an individual, (b) choosing a set of selected regions from the set of chosen regions to form a set of selected regions and a set of unused regions, (c) conducting a iterative algorithm on the set of selected regions until a domain number for the set of selected regions has decreased to a predetermined minimum, (d) determining a replication timing footprint based the set of selected regions after step (c) has been conducted, and (e) displaying the replication timing footprint to a user. | 05-29-2014 |
20140288847 | SYSTEMS AND TECHNIQUES FOR SEGMENTATION OF SEQUENTIAL DATA - An efficient method and associated systems for segmentation of high throughput sequential data, such as genomic datasets. The technique first utilizes dynamic programming to compute the significance for a large number of candidate segments. It then uses tree-based data structures to detect overlapping significant regions and update them simultaneously. Refinement and merging of significant segments are performed at the end to generate the final segmentation. | 09-25-2014 |
20150066483 | AUTOMATED EXTRACTION OF BIO-ENTITY RELATIONSHIPS FROM LITERATURE - Automated, standardized and accurate extraction of relationships within text. Automatic extraction of such relationships/information allows the information to be stored in structured form so that it can be easily and accurately retrieved when needed. Such information can be used to build online search engines for highly specific and accurate information retrieval. The current invention discloses a novel approach to extract such information from raw text based on natural language processing (NLP) and graph theoretic algorithm. The novel method can be applied, for example, to extract protein-protein relationships in biomedical literature. The method can be easily extended to extract other biological relationships between biological terms such as proteins, genes, pathways, diseases and drugs. The method can also be applied to other information domains to extract other relationships. | 03-05-2015 |
Patent application number | Description | Published |
20080227648 | Winding for Use in High Temperature Superconducting Generator - A winding for use in a superconducting electric generator having a rotating rotor assembly surrounded by a non-rotating stator assembly is provided. The winding comprises at least one conductor structure associated with a component in the superconducting electric generator. The conductor structure comprises a plurality of conductive elements formed from a high temperature superconductive material. At least a portion of the conductive elements is arranged in a transposed relationship. A protective shell is positioned about the conductive elements and formed from a high strength alloy suitable for cryogenic temperatures. | 09-18-2008 |
20090315425 | SUPERCONDUCTING COIL SUPPORT STRUCTURES - Support structures ( | 12-24-2009 |
20100201220 | ROTOR WINDING SHIELD FOR A SUPERCONDUCTING ELECTRIC GENERATOR - A generator rotor core ( | 08-12-2010 |
20100299913 | ROTOR POLE CROSSOVER CONNECTION - A rotor pole crossover connection joint for use in a rotating electrical machine is disclosed. The connection joint integrally couples a bottom rotor coil strap to a rotor pole crossover connector with a single piece connector that reduces, distributes or otherwise tolerates stress concentrations in the connector. A corresponding method of forming a rotor pole crossover connection and a rotor assembly including a rotor pole crossover connection joint are also disclosed | 12-02-2010 |
20120204574 | GAS TURBINE ENGINE - A power turbine receiving cooling fluid from compressor apparatus is provided. The turbine comprises: fixed housing structure; a support shaft rotatably supported in the housing structure; at least one disk overhung on the support shaft and coupled to the support shaft so as to rotate with the support shaft; and cooling fluid structure. The at least one disk is formed from a low-alloy-content steel. The cooling fluid supply structure extends through the support shaft and the at least one disk so as to supply cooling fluid to the at least one disk. | 08-16-2012 |
20140056686 | COOLING AIR CONFIGURATION IN A GAS TURBINE ENGINE - Cooling air is provided from a source of cooling air through a cooling air circuit in a turbine section of a gas turbine engine. A first portion of cooling air is provided from the source along a first path of the circuit to a plurality of blades associated with a stage of the turbine section. A second portion of cooling air is provided from the source along a second path of the circuit. The second path includes a turbine disc bore where the cooling air provides cooling to a radially innermost portion of at least one turbine disc that forms a part of a rotor of the engine. The second path is independent from the first path such that the second portion of cooling air bypasses the stage and is not mixed with the first portion of cooling air in the circuit after leaving the source. | 02-27-2014 |
20140060068 | METHOD FOR OPERATING A GAS TURBINE ENGINE INCLUDING A COMBUSTOR SHELL AIR RECIRCULATION SYSTEM - During full load operation of gas turbine engine operation, a valve system is maintained in a closed position to substantially prevent air from passing through a piping system of a shell air recirculation system. Upon initiation of a turn down operation, which is implemented to transition the engine to a turning gear state or a shut down state, the valve system is opened to allow air to pass through the piping system. A blower is operated to extract air through at least one outlet port of the shell air recirculation system from an interior volume of an engine casing portion associated with the combustion section, to convey the extracted air through the piping system, and to inject the air into the interior volume of the engine casing portion through at least one inlet port of the shell air recirculation system to circulate air within the engine casing portion. | 03-06-2014 |
20140060082 | COMBUSTOR SHELL AIR RECIRCULATION SYSTEM IN A GAS TURBINE ENGINE - A shell air recirculation system for use in a gas turbine engine includes one or more outlet ports located at a bottom wall section of an engine casing wall and one or more inlet ports located at a top wall section of the engine casing wall. The system further includes a piping system that provides fluid communication between the outlet port(s) and the inlet port(s), a blower for extracting air from a combustor shell through the outlet port(s) and for conveying the extracted air to the inlet port(s), and a valve system for selectively allowing and preventing air from passing through the piping system. The system operates during less than full load operation of the engine to circulate air within the combustor shell but is not operational during full load operation of the engine. | 03-06-2014 |
20140119880 | TEMPERATURE CONTROL WITHIN A CAVITY OF A TURBINE ENGINE - A turbine engine including an intermediate space defined between outer and inner portions of the turbine engine. A flow energizer is provided including a flow body located within the intermediate space and including an inlet port, an outlet port and a flow passage extending within the flow body between the inlet and outlet ports. The inlet port receives a flow of a first medium located within the intermediate space and the flow body injects an energizing flow of a second medium to a portion of the first medium within the flow body to create an energized flow of a mixed medium from the outlet portion, the energized flow of mixed medium creates a flow of the first medium adjacent to the flow body within the intermediate space. | 05-01-2014 |
20140301820 | TURBINE ENGINE SHUTDOWN TEMPERATURE CONTROL SYSTEM WITH NOZZLE INJECTION FOR A GAS TURBINE ENGINE - A turbine engine shutdown temperature control system configured to limit thermal gradients from being created within an outer casing surrounding a turbine blade assembly during shutdown of a gas turbine engine is disclosed. By reducing thermal gradients caused by hot air buoyancy within the mid-region cavities in the outer casing, arched and sway-back bending of the outer casing is prevented, thereby reducing the likelihood of blade tip rub, and potential blade damage, during a warm restart of the gas turbine engine. The turbine engine shutdown temperature control system may operate during the shutdown process where the rotor is still powered by combustion gases or during turning gear system operation after shutdown of the gas turbine engine, or both, to allow the outer casing to uniformly, from top to bottom, cool down. | 10-09-2014 |
20140301834 | TURBINE CYLINDER CAVITY HEATED RECIRCULATION SYSTEM - A turbine engine heating system configured to heat compressor and turbine blade assemblies to eliminate turbine and compressor blade tip rub during warm restarts of gas turbine engines is disclosed. The turbine engine heating system may include a heating air extraction system configured to withdraw air from the turbine engine and to pass that air thru a heating element configured to increase a temperature of the air supplied by the heating air extraction system. The air may then be passed to a heating air supply system via an air movement device. The heating air supply system may be in communication with a turbine cylinder cavity of the turbine engine positioned radially outward from at least one turbine assembly. The heated air may be passed into the turbine cylinder cavity to reduce the cooling rate of the turbine vane carriers after shutdown and before a warm restart to limit tip rubbing. | 10-09-2014 |
20140321981 | TURBINE ENGINE SHUTDOWN TEMPERATURE CONTROL SYSTEM - A turbine engine shutdown temperature control system configured to foster consistent air temperature within cavities surrounding compressor and turbine blade assemblies to eliminate turbine and compressor blade tip rub during warm restarts of gas turbine engines is disclosed. The turbine engine shutdown temperature control system may include one or more air amplifiers positioned in a turbine case. An exhaust outlet of the air amplifier may extend into a cavity created by a turbine case and may be configured to exhaust air in a generally circumferential direction to entrain air within the cavity to flow circumferentially to establish a consistent air temperature within the cavity thereby preventing uneven cooling of turbine engine components after shutdown and prevent damage to turbine components during a warm restart. | 10-30-2014 |
Patent application number | Description | Published |
20110207663 | FIBROBLAST GROWTH FACTOR (FGF) ANALOGS AND USES THEREOF - The invention relates to novel peptide comprising FGF-P and methods of use thereof. | 08-25-2011 |
20120003625 | METHODS AND KITS FOR DETECTING AN INFECTIOUS AGENT - The present invention provides methods and kits for determining the presence, absence, or level of an infectious agent in a sample. Specifically, the present invention provides methods and kits for detecting or quantifying certain target polynucleotides of the infectious agent. In certain embodiments, the present invention provides for such detection without the need for amplification (e.g., replication) of the target molecule and/or without the need for labor intensive purification procedures. In certain embodiments, the present invention provides positive control and housekeeping gene for normalization and quantatively detection of the copy numbers of infectious agent in a sample. In these or other embodiments, the invention allows for such detection with the desired sensitivity and/or specificity, even where the polynucleotide is present in the sample at low copy number. | 01-05-2012 |
20120077748 | Materials and Methods for Improving Gastrointestinal Function - The subject invention provides therapeutic compositions, and uses thereof for the treatment or amelioration of injury to small intestine mucosa. In preferred embodiments, the composition comprises one or more nutrients and/or electrolytes that acquire or retain considerable absorptive capacity. | 03-29-2012 |
20130203052 | FREE CIRCULATING DNA BIO-MARKERS AND THEIR APPLICATIONS - This invention relates generally to methods for detecting cell damage as a consequence of pathophysiological or traumatic insults such as in a nuclear accident, bioterror attack, tumorigenesis, infections or in individuals with cardiovascular disease. | 08-08-2013 |
20140377374 | MATERIALS AND METHODS FOR TREATING DIARRHEA - The present invention provides therapeutic compositions and methods for treating gastrointestinal diseases and conditions such as diarrhea, for providing rehydration, for correcting electrolyte and fluid imbalances, and/or for improving small intestine function. In one embodiment, the present invention provides a composition formulated for enteral administration, wherein the composition does not contain glucose. In a preferred embodiment, the composition is formulated for administration as an oral rehydration drink. | 12-25-2014 |
20150044145 | MATERIALS AND METHODS FOR TREATMENT OF CYSTIC FIBROSIS AND FOR INDUCTION OF ION SECRETION - The present invention provides materials and methods for inducing ion secretion and/or for treating cystic fibrosis. In one embodiment, the composition comprises glucose and/or a non-metabolizable glucose analog and/or non-structural protein (NSP4), a NSP4 peptide, or a NSP4 toxoid as the active ingredient, formulated with pharmaceutically-acceptable carriers. In a preferred embodiment, the composition is in a form of an aerosol preparation for intranasal and/or pulmonary administration, and is used to stimulate chloride and fluid secretion in nasal, tracheal and/or bronchial epithelium. | 02-12-2015 |
20150196534 | Materials and Methods for Improving Gastrointestinal Function - The subject invention provides therapeutic compositions, and uses thereof for the treatment or amelioration of injury to small intestine mucosa. In preferred embodiments, the composition comprises one or more nutrients and/or electrolytes that acquire or retain considerable absorptive capacity. | 07-16-2015 |
20150297636 | MATERIALS AND METHODS FOR TREATING DIARRHEA - The present invention provides therapeutic compositions and methods for treating gastrointestinal diseases and conditions such as diarrhea, for providing rehydration, for correcting electrolyte and fluid imbalances, and/or for improving small intestine function. In one embodiment, the present invention provides a composition formulated for enteral administration, wherein the composition does not contain glucose. In a preferred embodiment, the composition is formulated for administration as an oral rehydration drink. | 10-22-2015 |
Patent application number | Description | Published |
20120009381 | CARBON NANOTUBE HONEYCOMB AND METHODS OF MAKING AND USE THEREOF - Materials that have a honeycomb structure are provided that are formed, at least in part, from carbon nanotube sheets. Methods are also provided for making these materials, including the expansion method, in which an adhesive is applied to carbon nanotube sheets, which are then stacked and expanded to form the honeycomb structure, or a corrugated method, in which an adhesive is applied to corrugated sheets, which are then stacked to form the honeycomb structure. | 01-12-2012 |
20120085970 | Composite Materials Reinforced with Carbon Nanotube Yarns - Composite materials are provided that include one or more CNT yarns embedded in a matrix material. The composite materials may be transparent. Methods for making the composite materials are also provided. The composite materials may be made by arranging at least one CNT yarn into a desired pattern and embedding the at least one CNT yarn into a matrix material. | 04-12-2012 |
20150013896 | Graphene Nanoribbons and Methods - Methods are provided for fabricating graphene nanoribbons. The methods rely on laser irradiation that is applied to a carbon nanotube film to unzip one or more carbon nanotubes of the carbon nanotube film. Graphene nanoribbons can be cross-linked via laser irradiation to form a graphene nanoribbon network. | 01-15-2015 |
20150147573 | NANOFIBER RIBBONS AND SHEETS AND FABRICATION AND APPLICATION THEREOF - The present invention is directed to nanofiber yarns, ribbons, and sheets; to methods of making said yarns, ribbons, and sheets; and to applications of said yarns, ribbons, and sheets. In some embodiments, the nanotube yarns, ribbons, and sheets comprise carbon nanotubes. Particularly, such carbon nanotube yarns of the present invention provide unique properties and property combinations such as extreme toughness, resistance to failure at knots, high electrical and thermal conductivities, high absorption of energy that occurs reversibly, up to 13% strain-to-failure compared with the few percent strain-to-failure of other fibers with similar toughness, very high resistance to creep, retention of strength even when heated in air at 450° C. for one hour, and very high radiation and UV resistance, even when irradiated in air. Furthermore these nanotube yarns can be spun as one micron diameter yarns and plied at will to make two-fold, four-fold, and higher fold yarns. Additional embodiments provide for the spinning of nanofiber sheets having arbitrarily large widths. In still additional embodiments, the present invention is directed to applications and devices that utilize and/or comprise the nanofiber yarns, ribbons, and sheets of the present invention. | 05-28-2015 |
20160002043 | Carbon Nanotube Foams with Controllable Architecture and Methods - CNT foams and methods are provided. The methods may include forming, in a non-solvent liquid, a suspension of CNTs and particles of a pyrolytic polymer; removing the non-solvent liquid; and removing the particles of the pyrolytic polymer to produce a CNT foam having cells that at least substantially correspond to the dimensions of the particles of the pyrolytic polymer. CNT foams having porous structures also are provided. | 01-07-2016 |
20160083872 | FABRICATION OF NANOFIBER RIBBONS AND SHEETS - Fabricating a nanofiber ribbon or sheet with a process that includes providing a primary assembly by arranging carbon nanotube nanofibers in aligned arrays, the arrays having a degree of inter-fiber connectivity, drawing the carbon nanotube nanofibers from the primary assembly into a sheet or ribbon, and depositing the sheet or ribbon on a substrate. | 03-24-2016 |
Patent application number | Description | Published |
20100208965 | Method and Apparatus for Tomographic Imaging of Absolute Optical Absorption Coefficient in Turbid Media Using Combined Photoacoustic and Diffusing Light Measurements - Embodiments of the invention pertain to methods for imaging a light absorption coefficient distribution. Embodiments of the subject method can be implemented without knowing the strength of incident light in advance and without requiring careful calibrations in the non-scattering medium. Embodiments of the method can combine conventional photoacoustic tomography (PAT) with diffusing light measurements coupled with an optimization procedure based on the photon diffusion equation. Images of absorbing targets as small as 0.5 mm in diameter embedded in a 50 mm diameter background medium can be quantitatively recovered. Small targets with various optical contrast levels relative to the background can be detected well. Embodiments of the subject reconstruction method can include first obtaining the map of absorbed optical energy density. Embodiments can obtain the map of absorbed optical energy density through a model-based reconstruction algorithm that is based on a finite element solution to the photoacoustic wave equation in frequency domain subject to the radiation or absorbing boundary conditions (BCs). The distribution of optical fluence can then be obtained. Embodiments can obtain the distribution of optical fluence using the photon diffusion equation based optimization procedure. The distribution of optical absorption coefficient can then be recovered from the distribution of optical fluence and the absorbed energy density. | 08-19-2010 |
20100254911 | MULTIMODAL NANOPARTICLES FOR NON-INVASIVE BIO-IMAGING - Multimodal nanoparticles are nanoparticles containing contrast agents for PAT and one or more of luminescence imaging, x-ray imaging, and/or MRI. The multimodal nanoparticles can have a dielectric core comprising an oxide with a metal coating on the core. The particles can be metal speckled. The multimodal nanoparticles can be used for therapeutic purposes such as ablation of tumors or by neutron capture in addition to use as contrast agents for imaging. | 10-07-2010 |
20110052495 | USE OF FULLERENES IN PHOTOACOUSTIC IMAGING - Fullerenes, when irradiated with electromagnetic radiation, generate acoustic waves. A photoacoustic tomography method using a material comprising fullerenes is disclosed that includes irradiating the material with a radiation beam such as a laser. The resultant photoacoustic effect produced by the material is detected by at least one detector. A photoacoustic tomography system using a material comprising fullerenes is also described. | 03-03-2011 |
20130129633 | MULTIMODAL NANOPARTICLES FOR NON-INVASIVE BIO-IMAGING - Multimodal nanoparticles are nanoparticles containing contrast agents for PAT and one or more of luminescence imaging, x-ray imaging, and/or MRI. The multimodal nanoparticles can have a dielectric core comprising an oxide with a metal coating on the core. The particles can be metal speckled. The multimodal nanoparticles can be used for therapeutic purposes such as ablation of tumors or by neutron capture in addition to use as contrast agents for imaging. | 05-23-2013 |
Patent application number | Description | Published |
20090069519 | COBALT-CATALYZED ASYMMETRIC CYCLOPROPANATION OF ELECTRON-DEFICIENT OLEFINS - Cobalt-catalyzed asymmetric cyclopropanation of electron-deficient olefins. | 03-12-2009 |
20100063277 | Intramolecular C-H amination with sulfonyl azides - Cobalt (II) complexes of porphyrins are effective catalysts for intramolecular nitrene insertion of C—H bonds with arylsulfonyl azides. The cobalt-catalyzed process can proceed efficiently under mild and neutral conditions in low catalyst loading without the need of other reagents or additives, generating nitrogen gas as the only byproduct. Using the simple tetraphenylporphyrin (TPP) as the ligand, the cobalt-catalyzed intramolecular amidation can be applied to primary, secondary, and tertiary C—H bonds and suitable for a broad range of arylsulfonyl azides, leading to the syntheses of various benzosultam derivatives in excellent yields | 03-11-2010 |
20100076239 | ASYMMETRIC CYCLOPROPANATION OF ELECTRON-DEFICIENT OLEFINS WITH DIAZO REAGENTS - Cobalt-catalyzed asymmetric cyclopropanation of electron-deficient olefins. | 03-25-2010 |
20100081838 | Cobalt-Catalyzed Asymmetric Cyclopropanation of Alkenes with alpha-Nitrodiazoacetates - A process for the cyclopropanation of olefins with a metal porphyrin catalyst and an acceptor/acceptor substituted diazo reagent. | 04-01-2010 |
20100174104 | COBALT-CATALYZED ASYMMETRIC CYCLOPROPANATION WITH DIAZOSULFONES - Asymmetric cyclopropanation of olefins with diazosulfones. | 07-08-2010 |
20110112288 | Metal Porphyrin Catalyzed Olefin Aziridination with Sulfonyl Azides - Cobalt(II) complex of P1 [Co(P1)], a new porphyrin that was designed on the basis of potential hydrogen bonding interactions in the metal-nitrene intermediate, is a highly active catalyst for olefin aziridination with azides. The [Co(P1)]-based system can be effectively employed for different combinations of aromatic olefins and arysulfonyl azides, synthesizing various sulfonylated aziridines in excellent yields. Besides its mild catalytic conditions, the Co-catalyzed aziridination process enjoys several attributes associated with the relatively low cost of cobalt and widely accessible arylsulfonyl azides. Furthermore, it generates stable dinitrogen as the only by-product. | 05-12-2011 |
20110207956 | INTRAMOLECULAR C-H AMINATION WITH PHOSPHORYL AZIDES - A highly effective Co(II)-based system has been developed for catalytic intramolecular C—H amination with phosphoryl azides without the need of terminal oxidant or other additives, resulting in the high-yielding production of cyclophosphoramidates with nitrogen gas as the by-product; additional features of this new catalytic system include the amination of primary C—H bonds and formation of 7-membered ring structures. | 08-25-2011 |
20120046455 | Catalytic Cyclopropanation of Alkenes with Alpha-Cyano-Diazoacetates - A process for the preparation of a 1,1-cyclopropane(nitrile)(electron-acceptor), the process comprising treating an olefin with an acceptor/acceptor-substituted α-cyanodiazo reagent in the presence of a catalytic amount of a metal porphyrin catalyst. | 02-23-2012 |
20120077959 | Asymmetric Cobalt-Catalyzed Cyclopropanation With Succinimidyl Diazoacetate - Cobalt(II) complexes of the D | 03-29-2012 |
20120077990 | Alkene Aziridination - A process for the asymmetric aziridination of an alkene comprising treating the alkene with a sulfonyl azide, preferably trichloroethoxysulfonyl azide, in the presence of a cobalt(II) porphyrin. | 03-29-2012 |
20120101271 | DIAMINE SYNTHESIS VIA CATALYTIC C-H AMINATION OF AZIDES - Selective intramolecular C—H amination via metalloradical activation of azides: synthesis of 1,3-diamines under neutral and nonoxidative conditions. One aspect of the present invention is the synthesis of 1,3-diamines by intramolecular C—H amination of sulfamoyl azides. More specifically, sulfamoyl azides may be selectively aminated via metalloradical activation of azides, preferably with Co(II) porphyrins. In a particularly preferred embodiment, the Co(II) porphyrin is a D | 04-26-2012 |
20130030170 | ENANTIOSELECTIVE CYCLOPROPENATION OF ALKYNES - The cobalt(II) complex of new D2-symmetric chiral porphyrin 3,5-DiMes-ChenPhyrin, [Co(P2)], has been shown to be a highly effective chiral metalloradical catalyst for enantioselective cyclopropenation of alkynes with acceptor/acceptor-substituted diazo reagents such as α-cyanodiazoacetamides and α-cyanodiazoacetates. The [Co(P2)]-mediated metalloradical cyclopropenation is suitable to a wide range of terminal aromatic and related conjugated alkynes with varied steric and electronic properties, providing the corresponding tri-substituted cyclopropenes in high yields with excellent enantiocontrol of the all-carbon quaternary stereogenic centers. In addition to mild reaction conditions, the Co(II)-based metalloradical catalysis for cyclopropenation features a high degree of functional group tolerance. | 01-31-2013 |
Patent application number | Description | Published |
20090184005 | Sensor for Measurement of Hydrogen Sulfide - An electrochemical sensor for measurement of hydrogen sulfide is described. The electrochemical sensor comprises an electrolyte; an electrolyte container comprising a hydrogen sulfide permeable membrane; a working electrode and a reference electrode both disposed in the electrolyte; and an instrument capable of maintaining a fixed DC potential in the range of 0 mV to 1,000 mV between the working electrode and the reference electrode. Also a method of detecting hydrogen sulfide in a sample. The method comprises providing an electrochemical sensor; at least partially immersing the gas permeable membrane in the sample; and detecting hydrogen sulfide in the sample. The detection may be qualitative or quantitative. | 07-23-2009 |
20120073988 | Sensor for Measurement of Hydrogen Sulfide - An electrochemical sensor for measurement of hydrogen sulfide is described. The electrochemical sensor comprises an electrolyte; an electrolyte container comprising a hydrogen sulfide permeable membrane; a working electrode and a reference electrode both disposed in the electrolyte; and an instrument capable of maintaining a fixed DC potential in the range of 0 mV to 1,000 mV between the working electrode and the reference electrode. Also a method of detecting hydrogen sulfide in a sample. The method comprises providing an electrochemical sensor; at least partially immersing the gas permeable membrane in the sample; and detecting hydrogen sulfide in the sample. The detection may be qualitative or quantitative. | 03-29-2012 |
20120184052 | Isolation and Analysis of Thiol Protein Matter Using Gold Nano-Particles - A method of rapidly and accurately identifying and analyzing thiol proteins in a sample using gold nanoparticles. Disclosed are embodiments of a flow device for isolation, fractionation and subsequent instrumental analysis of thiol containing proteins from various samples or tissue sources using gold nanoparticles. Also disclosed are embodiments of a flow device for detecting, isolating and fractionating S-nitrosated proteins and peptides for subsequent analysis, including identification of S-nitrosation sites. | 07-19-2012 |
20140296773 | APPARATUS FOR THE CONTROLLED RELEASE OF TOPICAL NITRIC OXIDE - A stable delivery system for the therapeutic release and application of nitric oxide to a patient suffering from a cutaneous injury or wound includes a S-nitrosothiol and transition element nanoparticles. The transition metal nanoparticles are selected to react with the S-nitrosothiol to release and diffuse nitric oxide into the injury or wound. | 10-02-2014 |
Patent application number | Description | Published |
20150128971 | VAPORIZER - An electronic cigarette or vaporizer may include a shell and a cartomizer receivable within a chamber within a portion of the shell. The cartomizer may hold a vaporizable fluid, dry substance, or other vaporizable substance such as a wax. A charger may also be included which in one embodiment may be insertable into the chamber, and in another embodiment may be connectable to an end of the shell. Various electrical components, such as a printed circuit board, a rechargeable battery, various indicator lights, a sensor, and display screen, for instance, improve the functionality of the vaporizer from known vaporizers. Magnets are also provided in order to secure the cartomizer or the charger to the shell. | 05-14-2015 |
20150128972 | VAPORIZER, CHARGER AND METHODS OF USE - Vaporizer and/or electronic cigarette chargers useful for the recharging of rechargeable vaporizer or electronic cigarette power supplies such as batteries, compatible vaporizers and/or electronic cigarettes, their components, charging contacts, methods of their use and kits containing such chargers are disclosed. | 05-14-2015 |
20150128976 | VAPORIZER - An electronic cigarette or vaporizer may include a shell and a cartomizer receivable within a chamber within a portion of the shell. The cartomizer may hold a vaporizable fluid, dry substance, or other vaporizable substance such as a wax. A charger may also be included which in one embodiment may be insertable into the chamber, and in another embodiment may be connectable to an end of the shell. Various electrical components, such as a printed circuit board, a recharagable battery, various indicator lights, a sensor, and display screen, for instance, improve the functionality of the vaporizer from known vaporizers. Magnets may also be provided in order to secure the cartomizer or the charger to the shell. | 05-14-2015 |
20150305409 | VAPORIZER - An electronic cigarette or vaporizer may include a shell and a cartomizer receivable within a chamber within a portion of the shell. The cartomizer may hold a vaporizable fluid, dry substance, or other vaporizable substance such as a wax. A charger may also be included which in one embodiment may be insertable into the chamber, and in another embodiment may be connectable to an end of the shell. Various electrical components, such as a printed circuit board, a recharagable battery, various indicator lights, a sensor, and display screen, for instance, improve the functionality of the vaporizer from known vaporizers. Magnets may also be provided in order to secure the cartomizer or the charger to the shell. | 10-29-2015 |
Patent application number | Description | Published |
20110143375 | BIOMARKER DETECTION PROCESS AND ASSAY OF NEUROLOGICAL CONDITION - The subject invention provides a robust, quantitative, and reproducible process and assay for diagnosis of a neurological condition in a subject. The invention provides measurement of two or more biomarkers in a biological fluid such as CSF or serum resulting in a synergistic mechanism for determining the extent of neurological damage in a subject with an abnormal neurological condition and for discerning subtypes thereof or tissue types subjected to damage. | 06-16-2011 |
20130022982 | MICRO-RNA, AUTOANTIBODY AND PROTEIN MARKERS FOR DIAGNOSIS OF NEURONAL INJURY - Processes and materials are provided for the detection, diagnosis, or determination of the severity of a neurological injury or condition, including traumatic brain injury, multiple-organ injury, stroke, Alzeimer's disease, Pakinson disease and Chronic Traumatic Encephalopathy (CTE). The processes and materials include biomarkers detected or measured in a biological sample such as whole blood, serum, plasma, or CSF. Such biomarkers include Tau and GFAP proteins, their proteolytic breakdown products, brain specific or enriched micro-RNA, and brain specific or enriched protein directed autoantibodies. The processes and materials are operable to detect the presence of absence of acute, subacute or chronic brain injuries and predict outcome for the brain injury. | 01-24-2013 |
20130029362 | MARKERS AND ASSAYS FOR DETECTION OF NEUROTOXICITY - A process and assay for diagnosing neurotoxicity in a subject is provided. The extent of a neurotoxic insult to a subject is assessed through the measurement of one or more biomarkers in a biological fluid, such as CSF or serum. Other uses and advantages afforded include pre-market drug discovery, monitoring, drug neurotoxicity screening and post market assessment of safety and monitoring for drug of known potential neurotoxicity. | 01-31-2013 |
20150268252 | BIOMARKER ASSAY OF NEUROLOGICAL CONDITION - A robust, quantitative, and reproducible process and assay for diagnosis of a neurological condition in a subject is provided. With measurement of one or more autoantibodies to biomarkers in a biological fluid such as CSF or serum, the extent of neurological damage in a subject with an abnormal neurological condition is determined and subtypes thereof or tissue types subjected to damage are discerned. | 09-24-2015 |