Tania
Tania Bakelants, Olen BE
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20110020501 | Fiber Enriched, Protein Coated Cereal Products - A cereal product comprising cereal kernels, wherein the cereal kernels have been at least partially milled and are coated with a coating layer, said coating layer comprising a protein matrix having particles of a dietary fiber ingredient dispersed therein. Also provided is a method of making a fiber-enriched dry cereal product comprising the steps of: coating cereal kernels that have been at least partially milled with particles of a dietary fiber ingredient and an aqueous dispersion containing a protein; followed by drying the coated cereal kernels. The dietary fiber ingredient may be a powdered stabilized cereal bran. The coated cereal products can be cooked in excess water to give cooked products having high dietary fiber content and improved palatability. | 01-27-2011 |
Tania Bedrax-Weiss, Sunnyvale, CA US
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20090100036 | Methods and Systems for Classifying Search Results to Determine Page Elements - This invention relates to determining page elements to display in response to a search. A method embodiment of this invention determines a page element based on a search result. The method includes: ( | 04-16-2009 |
20110258025 | PAYMENT MODEL WITH ENDORSEMENTS - Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for providing compensation. In one aspect, a method includes receiving a request for an advertisement, and identifying an advertisement responsive to the request, wherein a good or service associated with the advertisement is associated with an endorsement provided by an endorser. The advertisement is provided in response to the request. An indication of a selection of the advertisement is received, and compensation is provided to the endorser upon receiving the indication of the selection of the advertisement. | 10-20-2011 |
20110258042 | Endorsements Used in Ranking Ads - Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for providing advertisements. In one aspect, a method includes receiving a request for an advertisement from a user device associated with a first user, and identifying advertisements responsive to the request. A determination is made that one of the advertisements describes a good or service that is associated with an endorsement provided by an endorser, and the endorser is recommended by a second user that belongs to a same social network as the first user. The advertisements are ranked based on one or more signals associated with each advertisement, wherein one of the signals for the one advertisement is the endorsement and is used in the ranking in response to the determination. The ranked advertisements are provided in response to the request. | 10-20-2011 |
20120317107 | Methods and Systems for Classifying Search Results to Determine Page Elements - This invention relates to determining page elements to display in response to a search. A method embodiment of this invention determines a page element based on a search result. The method includes: (1) determining a set of result classifications based on the search result, wherein each result classification includes a result category and a result score; and (2) determining the page element based on the set of result classifications. In this way, a classification is determined based on a search result and page elements are generated based on the classification. By using the search result, as opposed to just the query, page elements are generated that corresponds to a predominant interpretation of the user's query within the search results. As result, the page elements may, in most cases, accurately reflect the user's intent. | 12-13-2012 |
20130104028 | Extensible Framework for Ereader Tools - The functionality of an ereader module that is displaying an electronic book (“ebook”) is extended. A user identifier specifying a user using a client device executing the ereader module and an ebook identifier specifying the ebook displayed by the ereader module are received from the client device. One or more layers associated with the user are determined. One or more layers associated with the ebook are determined. A list of one or more layers is assembled. The layer list is transmitted to the client device. The client device enables the user to select a layer and use the selected layer to interact with content of the ebook. | 04-25-2013 |
20130311870 | EXTENSIBLE FRAMEWORK FOR EREADER TOOLS, INCLUDING NAMED ENTITY INFORMATION - Information about named entities referenced in an electronic book (ebook) is provided to a client device. An ebook identifier identifying the ebook is received from the client device. A set of layers available for use with the ebook is determined. The layers in the set provide information associated with the ebook and a layer in the set provides information associated with named entities referenced in content of the ebook. A content range identifying a range of content of the ebook for which layer information is requested and an identification of one or more of the layers in the set for which layer information is requested is received from the client device. Layer information associated with the ebook content identified by the content range for the identified layers is transmitted to the client device. The transmitted layer information includes information associated with named entities referenced by ebook content. | 11-21-2013 |
20140089305 | CLASSIFYING SEARCH RESULTS TO DETERMINE PAGE ELEMENTS - This invention relates to determining page elements to display in response to a search. A method embodiment of this invention determines a page element based on a search result. The method includes: (1) determining a set of result classifications based on the search result, wherein each result classification includes a result category and a result score; and (2) determining the page element based on the set of result classifications. In this way, a classification is determined based on a search result and page elements are generated based on the classification. By using the search result, as opposed to just the query, page elements are generated that corresponds to a predominant interpretation of the user's query within the search results. As result, the page elements may, in most cases, accurately reflect the user's intent. | 03-27-2014 |
20150100308 | Automated Formation of Specialized Dictionaries - A document analysis system analyzes a corpus of documents and automatically generates a dictionary of specialized phrases not already in conventional dictionaries. The dictionary generation process involves a series of operations on the phrases to identify the phrases most suitable for inclusion in a dictionary, such as phrase scoring and phrase clustering. The dictionary generation process also comprises the identification of one or more corresponding definitions for the various phrases identified for inclusion in the specialized dictionary. | 04-09-2015 |
20150248380 | EXTENSIBLE FRAMEWORK FOR EREADER TOOLS, INCLUDING NAMED ENTITY INFORMATION - Information about named entities referenced in an electronic book (ebook) is provided to a client device. An ebook identifier identifying the ebook is received from the client device. A set of layers available for use with the ebook is determined. The layers in the set provide information associated with the ebook and a layer in the set provides information associated with named entities referenced in content of the ebook. A content range identifying a range of content of the ebook for which layer information is requested and an identification of one or more of the layers in the set for which layer information is requested is received from the client device. Layer information associated with the ebook content identified by the content range for the identified layers is transmitted to the client device. The transmitted layer information includes information associated with named entities referenced by ebook content. | 09-03-2015 |
20150324349 | AUTOMATED READING COMPREHENSION - Methods and apparatus are disclosed for determining similarities and/or differences between entities in a segment of text based on various signals are presented, and for determining one or more likelihoods that one or more subjects found in a segment of text are capable of performing one or more associated actions based on various signals. | 11-12-2015 |
20150346930 | EXTENSIBLE FRAMEWORK FOR EREADER TOOLS - The functionality of an ereader module that is displaying an electronic book (“ebook”) is extended. A user identifier specifying a user using a client device executing the ereader module and an ebook identifier specifying the ebook displayed by the ereader module are received from the client device. One or more layers associated with the user are determined. One or more layers associated with the ebook are determined. A list of one or more layers is assembled. The layer list is transmitted to the client device. The client device enables the user to select a layer and use the selected layer to interact with content of the ebook. | 12-03-2015 |
20150363809 | Endorsements Used in Ranking Ads - Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for providing advertisements. In one aspect, a method includes receiving a request for an advertisement from a user device associated with a first user, and identifying advertisements responsive to the request. A determination is made that one of the advertisements describes a good or service that is associated with an endorsement provided by an endorser, and the endorser is recommended by a second user that belongs to a same social network as the first user. The advertisements are ranked based on one or more signals associated with each advertisement, wherein one of the signals for the one advertisement is the endorsement and is used in the ranking in response to the determination. The ranked advertisements are provided in response to the request. | 12-17-2015 |
Tania Carmenate Portilla, La Habana CU
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20150284441 | TGFBeta-derived polypeptides and uses thereof - The present invention relates to the field of Biotechnology and more particularly to the mutated polypeptides of TGFβ molecule whose primary sequence has a high homology with the sequence of human TGFβ. These muteins lose their ability to interact with ALK5 but maintain their ability to interact with other receptors that are part of the receptor complex (TβRII and TβRIII). They have the property of antagonizing the signaling of all natural variants of TGFβ ligands, dependent of ALK5 recruitment in the receptor complex, and have significant immunomodulatory effects. The present invention relates to pharmaceutical compositions comprising as active principle the polypeptides or fusion proteins disclosed and their use thereof given their modulating effect on the immune system in diseases such as cancer, diseases accompanied by fibrosis and chronic infectious diseases. | 10-08-2015 |
Tania Carmenate Portilla, Cerro. La Habana CU
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20140314709 | IL-2 DERIVATIVES POLYPEPTIDES WITH AGONIST ACTIVITY FOR THERAPY OF CANCER AND CHRONIC INFECTIONS - The present invention relates to polypeptides which share primary sequence with human IL-2, except for several amino acids that have been mutated. The mutations introduced substantially reduce the ability of these polypeptides to stimulate in vitro and in vivo regulatory T cells (T CD4+CD25+FoxP3+) and make them more effective in the therapy of murine transplantable tumors. Also includes therapeutic uses of these mutated variants, used alone or in combination with vaccines for the therapy of diseases such as cancer or infections where the activity of regulatory T cells (Tregs) is relevant. In another aspect the present invention relates to pharmaceutical compositions comprising as active principle the polypeptides disclosed. Finally, the present invention relates to the therapeutic use of the polypeptidess and pharmaceutical compositions disclosed due to their modulating effect of the immune system on diseases like cancer and chronic infectious diseases. | 10-23-2014 |
Tania Carmenate Portilla, Ciudad De La Habana CU
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20120315245 | IMMUNOMODULATOR POLYPEPTIDES DERIVED FROM IL-2 AND THEIR USE THEREOF IN THE THERAPEUTIC OF CANCER AND CHRONIC INFECTIONS - The present invention relates generally to polypeptides whose primary sequence has high sequence homology with human interleukin 2 (IL-2) with some punctual mutations in the sequence of native IL-2. The polypeptides of the present invention have an immunomodulatory effect on the immune system, which is selective/preferential on regulatory T cells. The present invention also relates to specific polypeptides whose amino acid sequence is disclosed herein. In another aspect the present invention relates to pharmaceutical compositions comprising as active ingredient the polypeptides disclosed. Finally, the present invention relates to the therapeutic use of the polypeptides and pharmaceutical compositions disclosed due to their immune modulating effect on diseases such as cancer and chronic infectious diseases. | 12-13-2012 |
Tania Castaño Calduch, Madrid ES
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20100152213 | COMPOUND THAT IS A DUAL INHIBITOR OF ENZYMES PDE7 AND/OR PDE4, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF - The invention relates to a series of dual inhibitors of enzymes PDE7 and PDE4, having formula (I) and to the use thereof in the production of pharmaceutical compositions for the treatment of inflammatory and/or autoimmune processes. | 06-17-2010 |
Tania Castaño Calduch, Madrid ES
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20100152213 | COMPOUND THAT IS A DUAL INHIBITOR OF ENZYMES PDE7 AND/OR PDE4, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF - The invention relates to a series of dual inhibitors of enzymes PDE7 and PDE4, having formula (I) and to the use thereof in the production of pharmaceutical compositions for the treatment of inflammatory and/or autoimmune processes. | 06-17-2010 |
Tania Cavaliero, Neuchatel CH
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20090197902 | Use of Pyrimidine Compounds in the Preparation of Parasiticides - The invention relates to the use of compounds of the general formula (I), wherein R | 08-06-2009 |
20100063090 | Composition for Repelling and Deterring Vermin - The invention describes essentially a non-therapeutical process for deterring vermin, which is based on the usage of the largely known beta amino-alcohol derivatives of formula (I), as defined herein before. Furthermore, it describes the corresponding vermin-deterring compositions which contain these substances as the active ingredient, compounds of the formula (I) for the preparation of vermin-deterring compositions, and the use of compounds of formula (I) in the defense against vermin. Thus, the invention describes how and in which form the compounds of the formula (I) or their acid addition salts are used to deter vermin from materials, places or warm-blooded animals. | 03-11-2010 |
20130143924 | COMPOSITION FOR REPELLING AND DETERRING VERMIN - The present invention is directed to a non-therapeutical process for deterring vermin, which is based on the usage of the largely known beta amino-alcohol derivatives of formula (I) | 06-06-2013 |
Tania Chan, Santa Ana, CA US
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20090139710 | SWELLABLE COMPOSITIONS AND METHODS AND DEVICES FOR CONTROLLING THEM - Swellable compositions and methods of using and controlling them are disclosed. In certain examples, the swellable composition may comprise an active phase responsive to swell upon exposure to a swelling fluid. In some examples, the active phase of the swellable composition is effective to deswell in response to an applied stimulus in the presence of the swelling fluid. In other examples, the swellable composition may further comprise a passive phase responsive to swell to a lesser degree than the active phase upon exposure to the swelling fluid. Devices and systems using the swellable compositions are also described. | 06-04-2009 |
Tania Chernov-Rogan, Los Altos, CA US
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20090221442 | SUBSTRATES AND SCREENING METHODS FOR TRANSPORT PROTEINS - A variety of methods for assaying libraries of test compounds as ligands and/or substrates of transport proteins, including both carrier-type and receptor-type transport proteins, are provided. Both in vitro and in vivo screening methods are disclosed. Also provided are methods for screening DNA libraries to identify members that encode transport proteins. Pharmaceutical compositions including compounds identified via the screening methods are also provided. | 09-03-2009 |
Tania Chubenko, Colts Neck, NJ US
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20130125402 | Feeding Utensil - Utensils including a cover for at least a portion of the working end of the utensil. The cover may be in the form of a “scoop” located at the rearward portion of the working end of a utensil so that a user, such as a child, may lift the utensil vertically and still avoid spilling a significant portion of the food. The utensil may include a handle having a handle portion thicker than a conventional child utensil handle. The handle may be curved for easier handling. The cover may include indicia such as a character appealing to a user, such as a cartoon, animated character, celebrity or the like. | 05-23-2013 |
Tania Crombet Ramos, Ciudad De La Habana CU
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20100196412 | HOMOGENEOUS VACCINE COMPOSITION FOR THE TUMOR TREATMENT AND ITS OBTAINING METHOD - The present invention relates to the biotechnological field and particularly to the human health. More particularly, the present invention relates to a vaccine composition for therapeutic use in cancer patients. | 08-05-2010 |
20130039940 | Homogenous Vaccine Composition Comprising a Conjugate of EGF and P64K for the Treatment of Tumors - A vaccine composition for therapeutic use thereof on cancer patients includes a chemical conjugate of human recombining Epidermic Growth Factor (hrEGF) and a combining protein P64k for performing a conjugation reaction which produces said chemical conjugate in a controlled and reproducible manner. The preferred conjugate surprisingly increases the immunogenic activity causing significant increases in the anti-EGF antibody titers in humans, and provides a vaccine preparation with more than one type of effective dose presentation which enables the immunization dose per patient to be increased, but without involving an increase in immunization frequency and/or the number of immunization sites. | 02-14-2013 |
Tania Degian, Toronto CA
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20120010160 | Rapidly Dissolving Oral Strip of Sugar for Hypoglycemia - A method of orally administering measured doses of sugar into the bloodstream for controlling glucose levels, particularly for those individuals with diabetes or those who experience difficulty maintaining healthy blood sugar levels. The method comprises providing packets of orally ingestible strips of a disintegrating matrix containing a dose of sugar to supplement food intake between meals or to rapidly increase glucose levels in an emergency situation. Hypoglycemia is a condition of low blood sugar (glucose) levels in the bloodstream, which can have varying reactions on individuals ranging from mild to severe. The disclosed matrix and method rapidly introduces sugar into the blood stream for combating a hypoglycemic reaction. The strips are easily deployable and quickly dissolve once placed on the tongue and mixed with saliva. They can be packaged in a small, easy-to-dispense, and transportable case that allows rapid use when a sugar supplement is required. | 01-12-2012 |
20130292409 | Blood Sugar Management System - The present invention is a system for managing blood sugar levels while on the go. A roll of water soluble sugar thin-film is contained within a specialized dispensing container. A sliding button is disposed on one side of the dispenser and actuates dispensing of a single sugar strip and advancement of a counter. Each sugar strip contains a predetermined dose of dextrose or other sugar in a rapidly dissolving oral film. Thus, diabetics and persons experiencing a blood sugar imbalance can rapidly dispense a measured dose of sugar that dissolves in saliva. A counter on the side of the dispenser tracks the number of remaining sugar strips, thereby ensuring that users who rely on ready availability of sugar strips are aware of their remaining supply. | 11-07-2013 |
Tania Dottorini, Perugia IT
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20130079237 | ALLERGEN MICROARRAY - The present invention relates to a method of assessing if a subject is at risk of developing or has already developed asthma, conjunctivitis or rhinitis. The invention further relates to antigen sets for use in such methods including identifying other suitable antigens correlated with asthma, conjunctivitis or rhinitis. | 03-28-2013 |
Tania Garcia Maceira, Cordoba ES
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20130203078 | NOVEL ULTRASENSITIVE CELL BASED SENSORS AND USES THEREOF - The present invention relates to a novel cell based sensor useful for drug discovery that comprises a cell line with professional regulated exocytosis of secretory granules transfected with a protease as a reporter polypeptide stored in the regulated secretory granules of the cell line with professional regulated exocytosis and having either an endogenous or a heterologous molecule as a modulator of regulated secretory granules exocytosis, such said granule stored protease reporter having at least: a high resistance to conditions already present inside the granules such as low pH and proteolysis by other proteases; enzymatic activity after exocytosis; a highly specific cleavage sequence; a very low level of secretion under unstimulated or basal conditions; and a high signal to background activity in a media compatible with cell culture viability and granule exocytosis for a high throughput robust and sensitive detection. | 08-08-2013 |
20150175661 | GPCR WITH IMPROVED CELL SURFACE EXPRESSION - The present invention surprisingly shows that the addition of a heterologous viral-GPCR (G protein-coupled receptor) derived sequence at the amino terminal end of GPCRs improves cell surface expression of such receptors in eukaryotic cells. Transfected cells expressing the above heterologous viral GPCRs on their surface are useful for cell based assays to identify test compounds that increases or modulate activity of a GPCR or a ligand of a GPCR for example for drug discovery, development of novel flavors in the food industry or development of sensors based on odor GPCRs. In addition, membrane extracts derived from transfected cells may be used for example for assays of compounds in drug discovery or for development of sensors comprising such membrane extracts for identification and/or quantification of volatile organic compounds. | 06-25-2015 |
20150260724 | CELL BASED SENSOR - Cell based sensor. The present invention relates to a novel cell based sensor useful for drug discovery that comprises a cell line with professional regulated exocytosis of secretory granules transfected with a non-protease hydrolase as a reporter polypeptide stored in the regulated secretory granules of the cell line with professional regulated exocytosis and having either an endogenous or a heterologous molecule as a modulator of regulated secretory granules exocytosis. Said granule stored non protease-hydrolase reporter having at least: a high resistance to conditions already present inside the granules such as low pH and proteolysis by other proteases; enzymatic activity after exocytosis; a highly specific substrate; absence of toxicity when cell thawing; a very low level of secretion under unstimulated or basal conditions; and a high signal to background activity in a media compatible with cell culture viability and granule exocytosis for a high throughput robust and sensitive detection. | 09-17-2015 |
Tania Garcia Mendiola, Madrid ES
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20100236942 | METHOD FOR ELECTROCHEMICAL DETECTION OF NUCLEIC ACID SEQUENCES - The present invention relates to a new compound derived from ruthenium, of formula (I), known as pentaamin ruthenium [3-(2-phenanthren-9-yl-vinyl)pyridine] complex, as well as the use thereof as an electrochemical indicator of hybridization in a method for the detection of hybridization between nucleic acid sequences, for the quantification of said sequences, as well as the detection of the presence of a mismatched base and the position thereof within a nucleic acid sequence. | 09-23-2010 |
Tania Grippi Vallotton, Corsier CH
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20090306069 | AZOLIDINONE-VINYL FUSED-BENZENE DERIVATIVES - The present invention is related to azolidinedione-vinyl fused-benzene derivatives of formula (I) for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, graft rejection or lung injuries. | 12-10-2009 |
Tania Grippi-Vallotton, Puplinge CH
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20090029997 | Thiazole Derivatives and Use Thereof - The present invention is related to thiazole derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries. | 01-29-2009 |
20100197681 | Triazolopyridine Compounds and Their Use as Ask Inhibitors - The present invention relates to triazolopyridine compounds according to Formula (I), their use as medicament, for treating autoimmune disorders, inflammatory diseases, cardiovascular diseases and/or neurodegenerative diseases and a process for their preparation. | 08-05-2010 |
20120115895 | TRICYCLIC INDOLE-DERIVED SPIRO DERIVATIVES AS CRTH2 MODULATORS - The present invention relates to compounds of formula (I) for use as pharmaceutical active compounds, as well as pharmaceutical formulations containing the same, for the treatment of allergic diseases. The compounds according to Formula (I) are suitable as modulators of CRTH2. The invention provides Spiro derivatives according to Formula (I) and related formulae that are useful in the treatment and/or prevention of diseases selected from allergic diseases such as allergic asthma, allergic rhinitis, allergic conjunctivitis, and inflammatory dermatoses such as atopic dermatitis, contact hypersensitivity, allergic contact dermatitis, chronic urticaria/chronic idiopathic/autoimmune urticaria, drag-induced exanthems (e.g., toxic epidermal necrolysis or Lyell's syndrome/Stevens-Johnson syndrome/drug hypersensitivity syndrome), photodermatosis or polymorphous light emption (e.g., photoirritant contact dermatitis, photoallergy contact dermatitis, chronic actinic dermatitis), and myositis neurodegenerative disorders such as neuropatic pain and other diseases with an inflammatory component such as rheumatoid arthritis, multiple sclerosis, osteoarthritis, and inflammatory bowel disease (IBD). | 05-10-2012 |
20120238565 | TRIAZOLOPYRIDINE COMPOUNDS AND THEIR USE AS ASK INHIBITORS - The present invention relates to triazolopyridine compounds according to Formula (I), their use as medicament, for treating autoimmune disorders, inflammatory diseases, cardiovascular diseases and/or neurodegenerative diseases and a process for their preparation. | 09-20-2012 |
20130274241 | INDAZOLYL TRIAZOL DERIVATIVES - Compounds of Formula (I) | 10-17-2013 |
Tania Incitti, Roma IT
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20120129920 | miR-31 IN DUCHENNE MUSCULAR DYSTROPHY THERAPY - The invention relates to the therapy of Duchenne Muscular Dystrophy (DMD) by means of modulating the amount of a specific miRNA (miR-31). | 05-24-2012 |
Tania Incitti, Rome IT
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20110301218 | MODIFIED snRNAs FOR USE IN THERAPY - The invention relates to a nucleic acid encoding a small nuclear RNA (snRNA), which snRNA is modified so that it contains sequence capable of hybridizing with the 5′ and 3′ splice site junctions and an exonic splicing enhancer of an exon of a pre-mRNA, so that the exon sequence is skipped during the splicing process that converts the pre-mRNA in the mature mRNA. The nucleic acid, the modified snRNA and vectors incorporating the nucleic acid may be used in the therapy, in particular in the treatment of muscular dystrophies. | 12-08-2011 |
Tania Kosburd, Lod IL
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20100220484 | SLIM WAVEGUIDE COUPLING APPARATUS AND METHOD - In various embodiments, an illumination structure includes a discrete light source disposed proximate a bottom surface of a waveguide and below a depression in a top surface thereof. A top mirror may be disposed above the discrete light source to convert modes of light emitted from the discrete light source into trapped modes, thereby increasing the coupling efficiency of the illumination structure. | 09-02-2010 |
20130058610 | SLIM WAVEGUIDE COUPLING APPARATUS AND METHOD - In various embodiments, an illumination structure includes a discrete light source disposed proximate a bottom surface of a waveguide and below a depression in a top surface thereof. A top mirror may be disposed above the discrete light source to convert modes of light emitted from the discrete light source into trapped modes, thereby increasing the coupling efficiency of the illumination structure. | 03-07-2013 |
20150049507 | SLIM WAVEGUIDE COUPLING APPARATUS AND METHOD - In various embodiments, an illumination structure includes a discrete light source disposed proximate a bottom surface of a waveguide and below a depression in a top surface thereof. A top mirror may be disposed above the discrete light source to convert modes of light emitted from the discrete light source into trapped modes, thereby increasing the coupling efficiency of the illumination structure. | 02-19-2015 |
20160004001 | SLIM WAVEGUIDE COUPLING APPARATUS AND METHOD - In various embodiments, an illumination structure includes a discrete light source disposed proximate a bottom surface of a waveguide and below a depression in a top surface thereof. A top mirror may be disposed above the discrete light source to convert modes of light emitted from the discrete light source into trapped modes, thereby increasing the coupling efficiency of the illumination structure. | 01-07-2016 |
Tania Matamoros Grande, Madrid ES
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20160090580 | HIV TYPE 1 GROUP O REVERSE TRANSCRIPTASES THAT ARE ACTIVE AT HIGH TEMPERATURES - The present invention falls within the field of biotechnology. More specifically, the invention relates to reverse transcriptases expressed and purified in bacteria and having the amino acid sequence of the reverse transcriptase of a human immunodeficiency virus type 1 (HIV-1) group O, modified at positions 358, 359 and 360; and variants of this enzyme that contain additional changes at positions 355 and 357 or at 478 or position 69 (in this case accompanied by an insertion of two amino acids). These polymerases have greater activity than the non-mutated enzyme at high temperatures (above 60° C.). In addition, they retain the capacity for DNA synthesis at temperatures greater than 70° C. Moreover, the copying fidelity of these enzymes is not significantly different from that of the non-mutated reverse transcriptase. | 03-31-2016 |
Tania Nieves, Terrassa (barcelona) ES
Tania Pergam, Rishon Leziyyon IL
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20140255389 | POLYPEPTIDES AND POLYNUCLEOTIDES, AND USES THEREOF AS A DRUG TARGET FOR PRODUCING DRUGS AND BIOLOGICS - This invention relates to a novel target for production of immune and non-immune based therapeutics and for disease diagnosis. More particularly, the invention provides therapeutic antibodies against VSIG1, ILDR1, LOC253012, AI216611, C1ORF32 or FXYD3 antigens, which are predicted co-stimulatory family members and which are differentially expressed in cancers including, lung cancer, ovarian cancer, and colon cancer, and diagnostic and therapeutic usages. The use of these antibodies for modulating B7 costimulation and related therapies such as the treatment of autoimmunity are also provided. This invention further relates to the discovery of extracellular domains of VSIG1 and its variants, FXYD3 and its variants, ILDR1 and its variants, LOC253012 and its variants, AI216611 and its variants, and C1ORF32 and its variants which are suitable targets for immunotherapy, cancer therapy, and drug development. | 09-11-2014 |
20140255411 | POLYPEPTIDES AND POLYNUCLEOTIDES, AND USES THEREOF AS A DRUG TARGET FOR PRODUCING DRUGS AND BIOLOGICS - This invention relates to a novel target for production of immune and non-immune based therapeutics and for disease diagnosis. More particularly, the invention provides therapeutic antibodies against VSIG1, ILDR1, LOC253012, AI216611, C1ORF32 or FXYD3 antigens, which are predicted co-stimulatory family members and which are differentially expressed in cancers including, lung cancer, ovarian cancer, and colon cancer, and diagnostic and therapeutic usages. The use of these antibodies for modulating B7 costimulation and related therapies such as the treatment of autoimmunity are also provided. This invention further relates to the discovery of extracellular domains of VSIG1 and its variants, FXYD3 and its variants, ILDR1 and its variants, LOC253012 and its variants, AI216611 and its variants, and C1ORF32 and its variants a which are suitable targets for immunotherapy, cancer therapy, and drug development. | 09-11-2014 |
20140363446 | POLYPEPTIDES AND POLYNUCLEOTIDES, AND USES THEREOF AS A DRUG TARGET FOR PRODUCING DRUGS AND BIOLOGICS - This invention relates to a novel target for production of immune and non-immune based therapeutics and for disease diagnosis. More particularly, the invention provides therapeutic antibodies against VSIG1, ILDR1, LOC253012, AI216611, C1ORF32 or FXYD3 antigens, which are predicted co-stimulatory family members and which are differentially expressed in cancers including, lung cancer, ovarian cancer, and colon cancer, and diagnostic and therapeutic usages. The use of these antibodies for modulating B7 costimulation and related therapies such as the treatment of autoimmunity are also provided. This invention further relates to the discovery of extracellular domains of VSIG1 and its variants, FXYD3 and its variants, ILDR1 and its variants, LOC253012 and its variants, AI216611 and its variants, and C1ORF32 and its variants awhich are suitable targets for immunotherapy, cancer therapy, and drug development. | 12-11-2014 |
Tania Pergam, Rishon Lezion IL
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20120134997 | POLYPEPTIDES AND POLYNUCLEOTIDES, AND USES THEREOF AS A DRUG TARGET FOR PRODUCING DRUGS AND BIOLOGICS - This invention relates to a novel target for production of immune and non-immune based therapeutics and for disease diagnosis. More particularly, the invention provides therapeutic antibodies against VSIG1, ILDR1, LOC253012, AI216611, C1ORF32 or FXYD3 antigens, which are predicted co-stimulatory family members and which are differentially expressed in cancers including, lung cancer, ovarian cancer, and colon cancer, and diagnostic and therapeutic usages. The use of these antibodies for modulating B7 costimulation and related therapies such as the treatment of autoimmunity are also provided. This invention further relates to the discovery of extracellular domains of VSIG1 and its variants, FXYD3 and its variants, ILDR1 and its variants, LOC253012 and its variants, AI216611 and its variants, and C1ORF32 and its variants which are suitable targets for immunotherapy, cancer therapy, and drug development. | 05-31-2012 |
20150158947 | C10RF32 ANTIBODIES, AND USES THEREOF FOR TREATMENT OF CANCER - This invention relates to C1ORF32-specific antibodies, antibody fragments, alternative scaffolds, conjugates and compositions comprising same, for treatment of cancer. | 06-11-2015 |
Tania Pergam, Rishon Le Zion IL
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20110003708 | BIOMARKERS FOR THE PREDICTION OF RENAL INJURY - The present invention relates to means and methods for predicting the onset of renal injury based on measuring the expression of polynucleotides and proteins, particularly on measuring the expression of sets of novel as well as known polynucleotides and proteins, and to kits utilizing same. | 01-06-2011 |
20140220011 | POLYPEPTIDES AND POLYNUCLEOTIDES, AND USES THEREOF AS A DRUG TARGET FOR PRODUCING DRUGS AND BIOLOGICS - This invention relates to a novel target for production of immune and non-immune based therapeutics and for disease diagnosis. More particularly, the invention provides therapeutic antibodies against VSIG1, ILDR1, LOC253012, AI216611, ClORF32 or FXYD3 antigens, which are predicted co-stimulatory family members and which are differentially expressed in cancers including, lung cancer, ovarian cancer, and colon cancer, and diagnostic and therapeutic usages. The use of these antibodies for modulating B7 costimulation and related therapies such as the treatment of autoimmunity are also provided. This invention further relates to the discovery of extracellular domains of VSIG1 and its variants, FXYD3 and its variants, ILDR1 and its variants, LOC253012 and its variants, AI216611 and its variants, and ClORF32 and its variants which are suitable targets for immunotherapy, cancer therapy, and drug development. | 08-07-2014 |
Tania Pucovsky, Mississauga CA
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20110079018 | BLEED AIR TRANSFER TUBE - A fluid-conveying device including an inner tubular member with a circumferential end portion, a non-elastomeric ring received in a depression of the end portion, and an outer tubular member. The ring has a peripheral surface with a rounded contour defined along a longitudinal direction configured to remain out of the depression to engage the outer tubular member and facilitate sealing thereof. | 04-07-2011 |
Tania Puvirajesinghe, Marseille FR
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20160032005 | METHODS AND PHARMACEUTICALS COMPOSITIONS FOR TREATING BREAST CANCERS - The present invention relates to methods and pharmaceutical compositions for treating breast cancers. In particular, the present invention relates to a method for predicting the survival of a patient suffering from a breast cancer comprising i) determining the expression level of Vangl2 in a tumor sample obtained from the patient, ii) comparing the expression level determined at step i) with a predetermined reference value and iii) providing a poor prognosis when the expression level determined at step i) is higher than the predetermined reference value. The present invention also relates to a method for treating a patient suffering from a breast cancer comprising the steps consisting of i) predicting the survival of the patient according to claim | 02-04-2016 |
Tania Ripenbein, Natania IL
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20130244102 | ELECTROPHORETIC DEPOSITION OF THIN FILM BATTERIES - Methods for forming three-layer thin-film battery (TFB) structures by sequential electrophoretic deposition (EPD) on a single conductive substrate. The TFBs may be two-dimensional or three-dimensional. The sequential EPD includes EPD of a first battery electrode followed by EPD of a porous separator on the first electrode and by EPD of a second battery electrode on the porous separator. In some embodiments of a Li or Li-ion TFB, the separator includes a Li ion conducting solid. In some embodiments of a Li or Li-ion TFB, the separator includes an inorganic porous solid rendered ionically conductive by impregnation with a liquid or polymer. In some embodiments, the TFBs are coated and sealed with an EPDd PEEK layer. | 09-19-2013 |
Tania Ripenbein, Netanya IL
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20090142656 | 3-D MICROBATTERIES BASED ON INTERLACED MICRO-CONTAINER STRUCTURES - An electrical energy storage device ( | 06-04-2009 |
20110045351 | High-Power Nanoscale Cathodes for Thin-Film Microbatteries - A method, including placing a substrate of a battery in a bath consisting of a metal M chosen from a metal group consisting of Fe, Ni, Co, Cu, W, V, and Mn, an oxidant selected from an oxidant group consisting of oxygen and sulfur, and a polymer. The method also includes applying an electrical current so as to form on the substrate a metal M compound cathode having a nanoscale grain structure. | 02-24-2011 |
Tania Ripenbein, Natanya IL
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20160118684 | ELECTROPHORETIC DEPOSITION OF THIN FILM BATTERIES - Methods for forming three-layer thin-film battery (TFB) structures by sequential electrophoretic deposition (EPD) on a single conductive substrate. The TFBs may be two-dimensional or three-dimensional. The sequential EPD includes EPD of a first battery electrode followed by EPD of a porous separator on the first electrode and by EPD of a second battery electrode on the porous separator. In some embodiments of a Li or Li-ion TFB, the separator includes a Li ion conducting solid. In some embodiments of a Li or Li-ion TFB, the separator includes an inorganic porous solid rendered ionically conductive by impregnation with a liquid or polymer. In some embodiments, the TFBs are coated and sealed with an EPDd PEEK layer. | 04-28-2016 |
Tania Serovski, Botany AU
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20110052769 | PROCESS FOR SPRAYING NATAMYCIN ONTO BAKERY PRODUCTS AND USE OF HEAT FOR THE REMOVAL OF SOLVENT FROM BAKED PRODUCTS - The present invention provides a process for increasing the shelf life of bakery products, comprising baking a shaped dough in an oven; placing the shaped baked product on a bed, spraying a solution or suspension of natamycin in a solvent onto the surfaces of said shaped baked product, said spray being provided from sprayers located in at least two directions so as to deposit natamycin in an amount from 0.5 to 10 μg per cm | 03-03-2011 |
Tania Valdes-Gonzalez, Osaka JP
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20130066084 | EQUOL-CONTAINING EXTRACT, METHOD FOR PRODUCTION THEREOF, METHOD FOR EXTRACTION OF EQUOL, AND EQUOL-CONTAINING FOOD - The present invention relates to an extract obtained by extracting useful components containing equol from an equol-containing fermented soybean hypocotyl, and to a method for producing the same. | 03-14-2013 |
20130066085 | EQUOL-CONTAINING EXTRACT, METHOD FOR PRODUCTION THEREOF, METHOD FOR EXTRACTION OF EQUOL, AND EQUOL-CONTAINING FOOD - The present invention relates to an extract obtained by extracting useful components containing equol from an equol-containing fermented soybean hypocotyl, and to a method for producing the same. | 03-14-2013 |
20130136846 | EQUOL-CONTAINING EXTRACT, METHOD FOR PRODUCTION THEREOF, METHOD FOR EXTRACTION OF EQUOL, AND EQUOL-CONTAINING FOOD - The present invention relates to an extract obtained by extracting useful components containing equol from an equol-containing fermented soybean hypocotyl, and to a method for producing the same. | 05-30-2013 |
Tania Valdes-Gonzalez, Osaka-Shi JP
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20110033564 | EQUOL-CONTAINING EXTRACT, METHOD FOR PRODUCTION THEREOF, METHOD FOR EXTRACTION OF EQUOL, AND EQUOL-CONTAINING FOOD - The present invention relates to an extract obtained by extracting useful components containing equol from an equol-containing fermented soybean hypocotyl, and to a method for producing the same. | 02-10-2011 |
Tania Vojnovic, Siljian NO
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20110212183 | ANTIOXIDANT COMPOSITION FOR MARINE OILS COMPRISING TOCOPHEROL, ROSEMARY EXTRACT, ASCORBIC ACID AND GREEN TEA EXTRACT - The present invention relates to compositions suitable for improving oxidative stability of marine oils, marine oils having improved oxidative stability as well as methods for manufacturing such compositions. | 09-01-2011 |
Tania Zaverucha Do Valle, Paris FR
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20110104138 | USE OF THE INNATE IMMUNITY GENE OASL FOR PREVENTING OR TREATING INFECTION WITH NEGATIVE STRAND RNA VIRUSES - A method to treat a disease, disorder or condition caused by a negative-sense single-strand RNA virus in an individual in need, comprising at least the step of administering to said individual in need, an isolated 2′-5′-oligoadenylate synthetase like protein or an isolated polynucleotide encoding said 2′-5′-oligoadenylate synthetase like protein. | 05-05-2011 |