Schendel
Adam C. Schendel, Big Lake, MN US
Patent application number | Description | Published |
---|---|---|
20150330623 | CATALYTIC BURNER - A catalytic burner includes a porous diffuser member and a porous distributor member. At least one seal extends between the porous diffuser member and the porous distributor member thereby defining an oxidation chamber. Catalyst media particles for catalyzing an oxidation reaction of a fuel stream to produce heat and an exhaust stream is disposed within the oxidation chamber. The catalyst media particles comprise carrier particles. The carrier particles comprise refractory material, and at least some of the carrier particles have thereon an outer coating comprising an oxidation catalyst. The catalyst media particles have a void fraction of at least 0.6. | 11-19-2015 |
David Lawrence Schendel, Farmington Hills, MI US
Patent application number | Description | Published |
---|---|---|
20110056760 | Load Handling Bumper For Material Handling Device - A material handling device includes an automated guided vehicle configured for use with a carrier. Both the vehicle and the carrier include a bumper having a reflective target mounted thereon. The automated guided vehicle includes a sensor having a light source and a scanner for receiving a reflection from the light source. The light source directs a first light beam at the vehicle reflective target and a second light beam at the carrier reflective target. When the vehicle bumper is moved toward the sensor, the vehicle reflective target moves into a reflective position and when the carrier bumper is moved toward the sensor, the carrier reflective target moves into a reflective position. The movement of the either bumper into the reflective position generates a signal from the sensor to a controller to control the movement of the automated guided vehicle in response to movement of either bumper. | 03-10-2011 |
Dolores Schendel, Muenchen DE
Patent application number | Description | Published |
---|---|---|
20100189728 | Generation of Antigen Specific T Cells - The present invention is directed to a method of generating antigen specific T cells. Furthermore, the invention is directed to antigen specific T cells, isolated transgenic TCR's, pharmaceutical compositions containing same and their use in adoptive cell therapy. This invention in particular pertains to the use of cells co-expressing allogeneic MHC molecules and antigens to induce peptide-specific T cells from non-selected allogeneic T cell repertoires. | 07-29-2010 |
20100203086 | ATTACK OF TUMOR CELLS WITH MISSING, LOW OR ABERRANT MHC EXPRESSION BY COMBINING NON MHC-RESTRICTED T-CELLS/NK-CELLS AND MHC-RESTRICTED CELLS - This invention is directed to therapeutic compositions containing non-MHC-restricted Tcells/NK-cells in combination with MHC-restricted T-cells and especially to therapeutic compositions, which comprise LAK cells. Furthermore, the present invention is directed to the use of the above combination in the treatment of tumors in humans, which tumors show a missing, low or aberrant expression of MHC class Ia or Ib molecules. By using the aforementioned compositions/combinations it is possible to provide a balanced selective pressure against emergence of tumor cell variants that would otherwise escape immune detection. | 08-12-2010 |
20110182945 | SEMI-ALLOGENIC ANTI-TUMOUR VACCINE WITH HLA HAPLO-IDENTICAL ANTIGEN-PRESENTING CELLS - The present invention relates to semi-allogeneic antigen-presenting cells into which proteins and/or peptides or RNA or DNA or cDNA, respectively, encoding said proteins and/or peptides which are overexpressed in tumor cells or which are derived from autologous tumor cells or different tumor cells or different tumor cell lines have been introduced. Furthermore the invention relates to methods for the generation of these semi-allogeneic antigen-presenting cells as well as to the use thereof in the treatment of tumor diseases. | 07-28-2011 |
Dolores Schendel, Munchen DE
Patent application number | Description | Published |
---|---|---|
20110280889 | HIGH AFFINITY T CELL RECEPTOR AND USE THEREOF - The present invention is directed to a high affinity T cell receptor (TCR) against a tumor-associated antigen, an isolated nucleic acid molecule encoding same, a T cell expressing said TCR, and a pharmaceutical composition for use in the treatment of diseases involving malignant cells expressing said tumor-associated antigen. | 11-17-2011 |
20140288060 | Selective inhibition of MALT1 protease by phenothiazine derivatives - The invention relates to a compound for use in treating a cancer, wherein the cancer depends on the proteolytic activity of the MALT1 protease, and wherein the compound has the general formula (I) | 09-25-2014 |
Dolores J. Schendel, Munich DE
Patent application number | Description | Published |
---|---|---|
20100284976 | COMPOSITIONS FOR THE PREPARATION OF MATURE DENDRITIC CELLS - The invention relates to a method for in vitro maturation of at least one immature dendritic cell, comprising stimulating said immature dendritic cell with TNFα, IL-1β, IFNγ, a TLR7/8 agonist and prostaglandin E2 (PG). Furthermore, the invention relates to a composition comprising said factors as well as to mature dendritic cells produced by the method of the invention. | 11-11-2010 |
20120128704 | REPERTOIRE OF ALLO-RESTRICTED PEPTIDE-SPECIFIC T CELL RECEPTOR SEQUENCES AND USE THEREOF - The present invention is directed to a kit-of-parts or composition containing nucleic acid sequences coding for high-avidity, allo-restricted TCR, wherein the TCR are independently directed against the tyrosinase antigen, the melan-A antigen and the survivin antigen. The invention is further directed to a kit-of-parts or composition containing at least three groups of transgenic lymphocytes transformed with vectors coding for TCR against said antigens. Furthermore, the present invention provides a pharmaceutical composition and its use in the treatment of diseases involving malignant cells expressing said tumor-associated antigens. The invention further relates to a nucleic acid molecule coding for a TCR that recognizes the survivin antigen, a TCR encoded thereby and a T cell expressing said TCR. Further, the invention discloses a vector, a cell and a pharmaceutical composition encoding/containing same and their use in the treatment of diseases involving malignant cells expressing survivin. | 05-24-2012 |
20140302096 | COMPOSITIONS FOR THE PREPARATION OF MATURE DENDRITIC CELLS - The invention relates to a method for in vitro maturation of at least one immate dendritic cell, comprising stimulating said immature dendritic cell with TNFα, IL-1β, IFNγ, a TLR7/8 agonist and prostaglandin E2(PG). Furthermore, the invention elates to a composition comprising these factors as well as to mature dendritic cells produced by a method of the invention. | 10-09-2014 |
Dolores Jean Schendel, Muenchen DE
Patent application number | Description | Published |
---|---|---|
20110020308 | EXPRESSION OF TRANSGENIC T CELL RECEPTORS IN LAK-T CELLS - The present invention is directed to LAK-T cells, which have been transformed by a transgenic T cell receptor (tg-TCR). The invention is further directed to a method of generating those transgenic T cells, a pharmaceutical composition comprising said cells and the use of the LAK-T cells or of the pharmaceutical composition in the adoptive cell therapy and for treating hematological malignancies or solid tumors or acute or chronic infections or autoimmune diseases. | 01-27-2011 |
20140141026 | GENERATION OF ANTIGEN SPECIFIC T CELLS - The present invention is directed to a method of generating antigen specific T cells. Furthermore, the invention is directed to antigen specific T cells, isolated transgenic TCR's, pharmaceutical compositions containing same and their use in adoptive cell therapy. This invention in particular pertains to the use of cells co-expressing allogeneic MHC molecules and antigens to induce peptide-specific T cells from non-selected allogeneic T cell repertoires. | 05-22-2014 |
20140348805 | HIGH AFFINITY T CELL RECEPTOR AND USE THEREOF - The present invention is directed to a high affinity T cell receptor (TCR) against a tumor-associated antigen, an isolated nucleic acid molecule encoding same, a T cell expressing said TCR, and a pharmaceutical composition for use in the treatment of diseases involving malignant cells expressing said tumor-associated antigen. | 11-27-2014 |
Frederick J. Schendel US
Patent application number | Description | Published |
---|---|---|
20120291343 | SYNTHETIC COAL AND METHODS OF PRODUCING SYNTHETIC COAL FROM FERMENTATION RESIDUE - The invention herein describe a novel process for producing a novel synthetic coal product from fermentation residues, such as, the waste materials from fermentation based ethanol production. The fermentation residue is subject to a hydrothermal carbonization process in an aqueous solution at a temperature and at a pressure sufficient to form a synthetic coal solid and a liquid component. This process does not require drying of the fermentation residue which provides for a more energy efficient method of processing thereof. The synthetic coal solid has a high heat content combustive material. The liquid component has nutrient value so that it can be recycled thereby permitting the sustainable recycling of such nutrients and the water in which those nutrients are dissolved. | 11-22-2012 |
Frederick J. Schendel, Oakdale, MN US
Patent application number | Description | Published |
---|---|---|
20110056124 | Algal Coal and Process for Preparing Same - Algae-derived synthetic coal and filtrates. The invention described herein provides an algae-derived synthetic coal product and filtrates and process for preparing the same using an improved hydrothermal carbonization process. The synthetic coal product is similar to natural bituminous coal in terms of percent carbon content and energy equivalency while at the same time containing relatively low levels of sulfur and contaminant heavy metals. Unlike natural coal and other fossil fuels, because the carbon of the biomass is formed through photosynthesis, carbon dioxide formed during combustion is a “carbon neutral” event with little or no “new” carbon dioxide being added to the earth's atmosphere. The algae-derived filtrates contain useful constituents. | 03-10-2011 |
20110271588 | SYNTHETIC COAL AND METHODS OF PRODUCING SYNTHETIC COAL FROM FERMENTATION RESIDUE - Synthetic coal, methods of producing synthetic coal, produced from fermentation residue, such as the residue from ethanol production, by subjecting the fermentation residue to hydrothermal carbonization in an aqueous solution at a temperature and a pressure sufficient to form a synthetic coal solid and a liquid component. The solid synthetic coal component has a low ash content and may be used as a carbon source for energy production, such as for combustive thermal energy generation, or for gassification for the production of synthesis gas. | 11-10-2011 |
20130206571 | PROCESS FOR OBTAINING OILS, LIPIDS AND LIPID-DERIVED MATERIALS FROM LOW CELLULOSIC BIOMASS MATERIALS - The present invention concerns low energy requiring methods for processing low cellulosic biomass materials into oil, char and liquid components. One method comprises the steps of subjecting the biomass to hydrothermal carbonization under specified reaction conditions for producing a combined char and oil fraction as well as an aqueous fraction, separating the combined oil and char fraction from the aqueous fraction by filtration; separating the combined oil and char fraction into individual oil and char fractions using an organic solvent for forming an oil depleted char fraction and a liquid oil and solvent solution, and separating the liquid oil and solvent solution into individual oil and solvent fractions by distillation. | 08-15-2013 |
20140033777 | Methods of Producing Coal and Fertilizers from Fermentation Residues - The present invention concerns a process for producing synthetic coal and aqueous liquid plant fertilizing solution products from a fermentation residue such as is left over from the corn based process of producing ethanol. The synthetic coal has a high heat value commensurate with naturally occurring coals and is lower in ash and sulfur content and thus has value as a clean burning energy source. The aqueous fertilizer includes commercially useful amounts of phosphorous, potassium and nitrogen in solution. The process of the invention is also energy efficient in that the products produced thereby involve the use of substantially less energy as compared to the traditional methods of processing fermentation residues in the corn based ethanol production industry. | 02-06-2014 |
20150183641 | HYDROTHERMAL CARBONIZATION OF SEWAGE WASTES - The present disclosure provides methods for hydrothermally treating sewage wastes to preferably obtain valuable products, including fatty acids, carbon-neutral combustible hydrochar fuels, heavy metal salts for recycling into industrially important metals, and phosphoric acid and derivatives thereof. Fatty acids can be chemically transformed into useful products such as soaps, cosmetics and liquid transportation fuels such as biodiesel and conventional gasoline, diesel and aviation fuels; hydrochars created in the process can be combusted and the energy created used to generate electricity; heavy metal salts can be chemically reduced to form industrially important metals for use as catalysts; and phosphoric acid and its derivatives have very important roles as fertilizers in agriculture. | 07-02-2015 |
Jens Schendel, Berlin DE
Patent application number | Description | Published |
---|---|---|
20110098066 | CHARGING FOR SHORT MESSAGE DELIVERY - A short message service (SMS) node detects that at least one request to deliver a plurality of short messages (SM) originates from a single user. Information (MSISDN, ISMI) related to recipients of the plurality of short messages is combined in a signaling message, and the signaling message is transmitted to a charging function (OFCS, OCS). | 04-28-2011 |
Joerg Schendel, Stade DE
Patent application number | Description | Published |
---|---|---|
20100006202 | Apparatus and Method for Producing a Large-Area Fibre-Composite Structural Component - The present invention provides an apparatus and a method for producing a large-area fibre-composite structural component, in particular for the aircraft sector, comprising a predetermined shaping element, a controllable laying device for the defined laying of at least one fibrous sheet over or into the predetermined shaping element, a controllable turning device for a defined turning of the predetermined shaping element and of the laying device in relation to each other by a predetermined turning angle, and a central control device, which is connected to the laying device and the turning device for controlling of the same. | 01-14-2010 |
Michael Schendel, Andover, MN US
Patent application number | Description | Published |
---|---|---|
20100241179 | Techniques for Positioning Therapy Delivery Elements within a Spinal Cord or Brain - Apparatus and techniques to address problems associated with lead migration, patient movement or position, histological changes, neural plasticity or disease progression. Disclosed are techniques for implanting a lead having therapy delivery elements, such as electrodes or drug delivery ports, within a vertebral or cranial bone so as to maintain these elements in a fixed position relative to a desired treatment site. The therapy delivery elements may thereafter be adjusted in situ with a position control mechanism and/or a position controller to improve the desired treatment, such as electrical stimulation and/or drug infusion to a precise target. The therapy delivery elements may be positioned laterally in any direction relative to the targeted treatment site or toward or away from the targeted treatment site. A control system maybe provided for open- or closed-loop feedback control of the position of the therapy delivery elements as well as other aspects of the treatment therapy. | 09-23-2010 |
20140222142 | Heart Valve Prosthesis - Heart valve prosthesis are disclosed that include a frame or support structure having an inflow portion, a valve-retaining tubular or central portion and a pair of support arms. The inflow portion radially extends from a first end of the valve-retaining tubular portion and the pair of support arms are circumferentially spaced apart and radially extend from an opposing second end of the valve-retaining tubular portion. | 08-07-2014 |
Michael J. Schendel, Andover, MN US
Patent application number | Description | Published |
---|---|---|
20110004117 | IMPLANT PARAMETER SELECTION BASED ON COMPRESSIVE FORCE - Systems and techniques for determining in vivo mechanical load exerted on an implanted medical device (IMD) are described. A transfer function for determining a normal force exerted by a muscle based on an in-line force and muscle parameters is also described. | 01-06-2011 |
20110004124 | IMPLANTABLE MEDICAL DEVICE INCLUDING MECHANICAL STRESS SENSOR - Systems and techniques for determining in vivo mechanical load exerted on an implanted medical device (IMD) are described. The IMD or a device that has a substantially similar form factor as the IMD includes at least one mechanical stress sensor mechanically coupled to a housing or a component within the housing. In some examples, a patient parameter is determined based on a signal indicative of the in vivo mechanical load exerted on the IMD. In addition, in some examples, a processor determines whether a transient or cumulative mechanical load exerted on an IMD exceeded a predetermined threshold. A processor may additionally or alternatively determine whether a pattern in the mechanical loading of the IMD indicates a diversion from a manufacturing, shipping, storage or other handling process. | 01-06-2011 |
20120083866 | APPARATUS AND METHOD FOR EXPANDING A STIMULATION LEAD BODY IN SITU - An implantable lead is provided with at least one extendable member to position therapy delivery elements, which may be electrodes or drug delivery ports, after the lead has been inserted into the body. The lead may formed as a resilient element which is contained in a retainer tube that may be removed to permit the lead to deploy. Alternatively, a non-resilient lead may be provided with a slotted retainer tube. A series of mechanical linkages for expanding and retracting the lead within the human body may be actuated with various mechanisms. A control system may be provided for closed-loop feedback control of the position of the extendable members. The invention also includes a method for expanding an implantable lead in situ. | 04-05-2012 |
20120290976 | NETWORK DISTRIBUTION OF ANATOMICAL MODELS - Techniques for presenting a three-dimensional (3D) anatomical representation of an anatomical structure are described. 3D models of various anatomical structures may be stored as prepackaged anatomical data. A user device, e.g., a networked workstation, may receive the prepackaged anatomical data from a networked computing device, e.g., a server, and present at least a portion of a 3D model as a 3D anatomical representation. The user device may also present a menu with the 3D anatomical representation that allows the user to manipulate the 3D anatomical representation and measure various aspects of the 3D anatomical representation. In some examples, the user device may also present a representation of a medical device in conjunction with the 3D anatomical representation. | 11-15-2012 |
Olav Schendel, Stuttgart DE
Patent application number | Description | Published |
---|---|---|
20100260574 | RETAINING CAM FOR A ROTARY FASTENER - A retaining cam ( | 10-14-2010 |
20110185536 | HINGE FOR A PACKAGING BOX OR THE LIKE - A hinge for a packaging or cargo box or the like, having a first and a second hinge leaf, the second hinge leaf has a first bushing and a second bushing located at a distance therefrom, between which a bushing of the first hinge leaf can be rotated about a mutual hinge axis. An axial tube is rotationally fixed to the bushing of the first hinge leaf and is pivot-supported in the bushings of the second hinge leaf. A torsion spring is disposed in the axial tube and attached to one end of the axial tube. A torque support connects the other end of the torsion spring to the second hinge leaf in a rotationally fixed manner. A damper for the hinge movement is connected to the second hinge leaf and the axial tube. In a cylindrical hollow space of an outer opening, formed by the three bushings ( | 08-04-2011 |
20120091734 | LOCK FOR A LUGGAGE BOX - A lock for a luggage box installed overhead in the cabin of an aircraft, including a stationary housing and a cover that can move about a rotary axis. The lock includes a locking pin device that can be mounted on the housing, having two locking pins ( | 04-19-2012 |
20120248790 | LOCKING MECHANISM FOR A HOUSING AND LOCK SUITABLE THEREFOR - A locking mechanism ( | 10-04-2012 |
Stephen Schendel, Menlo Park, CA US
Patent application number | Description | Published |
---|---|---|
20140105856 | System and Method for Collagen Isolation - System and methods for isolation of collagen and other fibrous tissue from adipose tissue are described herein. The method of the present invention isolates the collagen from adipose tissue by sonication. The tissue to be sonicated is placed in a container or a flow cell transparent to ultrasound waves. After sonication the sonicated material is filtered out through the bottom of the flow cell and the sonicated collagen is trapped in the filter, which may be taken for further processing. The isolated collagen can then be combined with a suitable carrier for re-injection to correct various tissue defects such as wrinkles, to form a carrier for the stem cells, a filler, and matrix for new collagen production by injecting into the desired area of the host. | 04-17-2014 |
Stephen A. Schendel, Menlo Park, CA US
Patent application number | Description | Published |
---|---|---|
20080288004 | TISSUE SUSPENSION DEVICE - The present invention is an apparatus for suspending a soft tissue near a bone opening, which includes a bone anchor, a soft tissue anchor, a spacer, and a depth stop. The device of the present invention allows soft tissues to change positions and be held until sufficient healing has occurred. | 11-20-2008 |
20090149977 | METHODS, SYSTEMS, AND COMPUTER PROGRAM PRODUCTS FOR SHAPING MEDICAL IMPLANTS DIRECTLY FROM VIRTUAL REALITY MODELS - A virtual interactive environment enables a surgeon or other medical professional to manipulate implants, prostheses, or other instruments using patient-specific data from virtual reality models. The patient data includes a combination of volumetric data, surface data, and fused images from various sources (e.g., CT, MRI, x-ray, ultrasound, laser interferometry, PET, etc.). The patient data is visualized to permit a surgeon to manipulate a virtual image of the patient's anatomy, the implant, or both, until the implant is ideally positioned within the virtual model as the surgeon would position a physical implant in actual surgery. Thus, the interactive tools can simulate changes in an anatomical structure (e.g., bones or soft tissue), and their effects on the external, visual appearance of the patient. CAM software is executed to fabricate the implant, such that it is customized for the patient without having to modify the structures during surgery or to produce a better fit. | 06-11-2009 |
Yoel Schendel, Hod Hasharon IL
Patent application number | Description | Published |
---|---|---|
20150244865 | Cell Phone Application for Playing Voice Messages - An Internet application for cell phones that includes an independent dialer that enables the user to initiate phone calls from the cell phone and an option to extend the time interval between the moment the user finishes dialing and initiates the call and the moment the cell phone actually executes the call. During this time interval, the application plays back voice messages to the user. | 08-27-2015 |