Karel
Karel Bruneel, Gent BE
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20110078640 | PARAMETERIZED CONFIGURATION FOR A PROGRAMMABLE LOGIC DEVICE - The invention relates to a method and a tool for generating a parameterized configuration for a Field Programmable Gate Array from a Boolean function, the Boolean function comprising at least one parameter argument, comprising the steps generating at least one tunable logic block from the Boolean function and from at least one parameter argument, and mapping the at least one tunable logic block to the Field Programmable Gate Array. This is advantageous since a parameterized configuration can be generated faster than with conventional tools. | 03-31-2011 |
Karel Caslavsky, Toronto CA
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20080254731 | CONTROL WHEEL FOR AN AUTOMOTIVE AIR VENT - A control wheel for controlling a control in an automotive vent has a resilient bushing which provides a frictional force to retain the control wheel in a desired position. The frictional force is substantially independent of tolerances of the components of the control wheel due to expected manufacturing variations. | 10-16-2008 |
Karel De Brabandere, Kassel DE
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20090244936 | Three-phase inverter - The present invention relates to a three-phase inverter ( | 10-01-2009 |
20130099571 | Method for the Operational Control of an Inverter - A method for the operational control of an inverter designed for DC/AC voltage conversion that has at least one direct-voltage input and that can be connected to a power supply grid via at least one alternating-voltage output, the inverter being involved in a power flow interaction with the grid in such a manner that, during operation of the inverter, a leakage current I | 04-25-2013 |
Karel De Brabandere, Turnhout BE
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20130182477 | Method for Stabilizing an Electric Grid - A method for grid support by means of an inverter is disclosed, wherein the grid is supported by feeding in compensation currents. The method includes measuring a prevailing grid state, and breaking down voltages measured for measuring the prevailing grid state into symmetrical components of the grid state including positive sequence system components and negative sequence system components. The method further includes determining symmetrical components of a compensation current including positive sequence system components and negative sequence system components of the compensation current as functions of deviations of the positive sequence system components and negative sequence system components of the grid state from reference values, and feeding-in a compensation current as the vector sum of the determined symmetrical components of the compensation current | 07-18-2013 |
Karel De Bruijn, Blotzheim FR
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20120071537 | New Oral Formulation - The present invention relates to a pharmaceutical composition, in particular to a composition for administering active agents which are poorly soluble in aqueous media, and/or which are acid sensitive. | 03-22-2012 |
20130158092 | New Oral Formulation - The present invention relates to a pharmaceutical composition, in particular to a composition for administering active agents which are poorly soluble in aqueous media, and/or which are acid sensitive. | 06-20-2013 |
Karel De Rudder, Sint Jansteen NL
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20110004964 | INSECTICIDAL PROTEINS DERIVED FROM BACILLUS THURINGIENSIS - The present invention relates to the field of plant pest control, particularly insect control. Provided are nucleotide sequences from | 01-06-2011 |
20120302495 | INSECTICIDAL PROTEINS DERIVED FROM BACILLUS THURINGIENSIS - The present invention relates to the field of plant pest control, particularly insect control. Provided are nucleotide sequences from | 11-29-2012 |
20150246954 | INSECTICIDAL PROTEINS DERIVED FROM BACILLUS THURINGIENSIS - The present invention relates to the field of plant pest control, particularly insect control. Provided are nucleotide sequences from | 09-03-2015 |
Karel Domansky, Charlestown, MA US
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20130157283 | RAPID PATHOGEN DIAGNOSTIC DEVICE AND METHOD - A microfluidic device of a diagnostic and detection system includes an inlet port connected by one or more microchannels to an outlet port and includes a capture and visualization chamber (CVC) connected to at least one microchannel. A fluid to be analyzed can be mixed with magnetic microbeads that have an affinity to become bound to target components, such as pathogens in the fluid. The fluid including the magnetically bound target components can be injected through the microfluidic device. Magnetic field gradient, such as provided by permanent or electro-magnets, can be applied to the fluid and the magnetically bound target components flowing through the microfluidic device to cause the magnetically bound target components to migrate into the (CVC) and become separated from the fluid. The magnetically bound target components can be analyzed and tested using various techniques to detect the presence of specific organic and inorganic materials, such as pathogens in bio-fluids and contamination in liquid food sources (e.g. water). The device and method provide a system for rapidly detecting pathogens and contamination in relatively small fluid samples. | 06-20-2013 |
20130334120 | FLUID CLEANSING DEVICES AND METHODS OF USE - A system and method for removing a target species from a fluid source is provided. The system includes a reciprocating fluid cleansing device, including a processing chamber with a port at a first end for fluid passage and a movable plunger at a second end, wherein the plunger in contact with a fluid includes a motorized mixing element for mixing the fluid with species-targeting magnetic particles. Motion of the plunger in a first direction transfers a first volume of the fluid from the fluid source into the processing chamber. Motion of the plunger in a second direction transfers the first volume of the fluid from the processing chamber to a fluid destination. At least one magnetic element provides a magnetic field gradient within the processing chamber. A connector connects the port of the first processing chamber to the fluid source and the fluid destination. | 12-19-2013 |
20140158233 | AEROSOL DELIVERY TO A MICROFLUIDIC DEVICE - The present invention is directed to systems and methods for delivering aerosolized micro-droplets into microfluidic devices. In some embodiments, the microfluidic devices are designed for the culture of living cells at an air interface. In some embodiments, the systems and methods described herein can be used to deliver aerosolized micro-droplet into detection systems and small animals, tissues, organs and organisms. | 06-12-2014 |
20140199764 | MICROFLUIDIC MODULE AND USES THEREOF - Described herein are microfluidic modules and methods for making the same, wherein the microfluidic modules include a substrate comprising at least one ether-based, aliphatic polyurethane, and at least one fluidic element disposed therein. The ether-based aliphatic polyurethane can be either the substrate of the microfluidic modules or a coating of another substrate material, such that at least a portion of the ether-based, aliphatic polyurethane is in fluid communication. In one embodiment, the ether-based, aliphatic polyurethane includes dicyclohexylmethane-4,4′-diisocyanate. As the ether-based aliphatic polyurethane can decrease absorption of molecules, e.g., hydrophobic molecules, in such microfluidic modules, the microfluidic modules described herein can be used in various applications such as drug screening and fluorescent microscopy. | 07-17-2014 |
20140220617 | DIALYSIS LIKE THERAPEUTIC (DLT) DEVICE - A dialysis like therapeutic (DLT) device is provided. The DLT device includes at least one source channel connected at least one collection channels by one or more transfer channels. Fluid contacting surface of the channels can be an anti-fouling surface such as slippery liquid-infused porous surface (SLIPS). Fluids can be flown at high flow rates through the channels. The target components of the source fluid can be magnetic or bound to magnetic particles using an affinity molecule. A source fluid containing magnetically bound target components can be pumped through the source channel of the microfluidic device. A magnetic field gradient can be applied to the source fluid in the source channel causing the magnetically bound target components to migrate through the transfer channel into the collection channel. The collection channel can include a collection fluid to flush the target components out of the collection channel. The target components can be subsequently analyzed for detection and diagnosis. The source channel and the collection channels of the microfluidic device are analogous to the splenic arterioles and venules, respectively; the transfer channels mimic the vascular sinusoids of the spleen where opsonized particles are retained. Thus, the device acts as a dialysis like therapeutic device by combining fluidics and magnetics. | 08-07-2014 |
20150079670 | DEVICES AND METHODS FOR IN VITRO AEROSOL DELIVERY - A system and methods for aerosol delivery of an entity or agent are disclosed. The system and methods can include a target application surface. A nebulizer can be located in close proximity to the target application surface. The nebulizer can include a chamber to hold the entity, a nozzle plate including one nozzle, and a piezoelectric element coupled to the nozzle plate. A power source can be coupled to the piezoelectric element. The power source, when activated, can energize the piezoelectric element to vibrate the nozzle plate to cause the entity to be nebulized through the nozzle to impact the target application surface. | 03-19-2015 |
Karel Dudr, Trebic CZ
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20140260146 | Method and Device for Manufacturing a Filter Element and Filter Element - In a method for manufacturing a filter element for filtration of a fluid, a filter medium web is treated along at least one treatment line and the filter medium web is cut along at least one cutting line that is adjacent to the at least one treatment line. An apparatus for performing the method has a combination of at least one treatment device and at least one cutting device. The at least one treatment device has at least one treatment element that treats a filter medium web along at least one treatment line. The at least one cutting device has at least one cutting element that cuts the filter medium web along at least one cutting line. The at least one treatment element and the at least one cutting element, viewed in a movement direction of the filter medium web relative to the apparatus, are arranged staggered relative to each other. | 09-18-2014 |
Karel Eeckhout, Leuven BE
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20140336346 | PURIFICATION OF A HYDROCARBON STREAM - A process for producing a purified hydrocarbon stream can include contacting a hydrocarbon stream contaminated with one or more organoaluminum compounds with a chemical agent that is capable of reacting with the one or more organoaluminum compounds. | 11-13-2014 |
Karel HÁna, Ricany U Prahy CZ
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20130310831 | JAWED ENDOSCOPIC INSTRUMENT FOR ELECTROSURGERY - A jawed endoscopic instrument for electrosurgery is designed as a two-section tool, where one section includes a supporting rod with a fixed jaw portion, the other section a movable jaw portion attached to the supporting rod with the fixed jaw portion with a pin joint. A magnet is inserted in the movable jaw portion and covered with a clamped electrode, and another magnet mounted on a pull is inserted into the cavity of the supporting rod with the fixed jaw portion and covered with another electrode. When the pull moves, the movable jaw portion will be opened or closed relative to the supporting rod with the fixed jaw portion due to a change in the magnetic field between the magnets. | 11-21-2013 |
Karel Hauk, Warrenville, IL US
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20110194792 | BUSHING, PIECE WITH BUSHING, OR METHOD OF PRODUCING - This disclosure relates to bushings produced with adapted dovetails for production on a carrying web of a progressive stamping machine at a plurality of stations. The bushing includes a regular shape male dovetail inserted into an irregular shape crenellated female opening at the conclusion of a plurality of operations at stations on a progressive stamping machine. Once the bushing is bent in shape, in a subsequent step, the regular shape male dovetail is punched to lock in place into the irregular shape crenellated female opening. | 08-11-2011 |
20140099050 | METHOD OF PRODUCING BUSHING AND PIECE WITH BUSHING - This disclosure relates to bushings produced with adapted dovetails for production on a carrying web of a progressive stamping machine at a plurality of stations. The bushing includes a regular shape male dovetail inserted into an irregular shape crenellated female opening at the conclusion of a plurality of operations at stations on a progressive stamping machine. Once the bushing is bent in shape, in a subsequent step, the regular shape male dovetail is punched to lock in place into the irregular shape crenellated female opening. | 04-10-2014 |
20160003296 | METHOD OF PRODUCING BUSHING AND PIECE WITH BUSHING - This disclosure relates to bushings produced with adapted dovetails for production on a carrying web of a progressive stamping machine at a plurality of stations. The bushing includes a regular shape male dovetail inserted into an irregular shape crenellated female opening at the conclusion of a plurality of operations at stations on a progressive stamping machine. Once the bushing is bent in shape, in a subsequent step, the regular shape male dovetail is punched to lock in place into the irregular shape crenellated female opening. | 01-07-2016 |
Karel Havlovic, Praha CZ
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20120149907 | PROCESS FOR PREPARING TRICHLOROAMMINEPLATINATE SALT AND THE PRODUCTS OBTAINED THEREIN - The present invention relates to a process for preparing a trichloroammineplatinate salt by reacting a tetrachloroplatinate salt in aqueous solution in the presence of ammonium chloride and an alkali chloride with one or more carbonate salts selected from the group consisting of potassium, sodium and ammonium carbonate while keeping the pH value below 7 during the reaction; the product obtained therein and a use thereof. | 06-14-2012 |
Karel Hladky, Fallowfield GB
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20100000879 | ELECTROCHEMICAL NOISE AS A LOCALIZED CORROSION INDICATOR - Systems and methods are presented for a method for measuring or monitoring localized corrosion in which an electrochemical noise (ECN) signal is sensed and filtered by a high-pass or band-pass filter to remove low frequency components not related to localized corrosion and a standard deviation of the filtered signal is computed and scaled to provide a localized corrosion value. | 01-07-2010 |
Karel Hrncirik, Vlaardingen NL
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20090123636 | Food Composition - A fluid wine extract comprising: (a) from 4.0 to 10.0 wt % of ethanol; preferably from 5.0 to 9.0 wt %, most preferred from 6.0.0 wt % to 8.0 wt %, (b) from 20 to 70 wt % of wine solids, more preferred from 25 to 65 wt %, most preferred from 30 to 60 wt %, (c) from 26 to 75 wt % of water, more preferred from 37.5 to 65 wt %, most preferred from 45 to 55 wt %, said wine extract having a pH of between 1.5 and 5.0 more preferred from 2.0 to 4.5, most preferred from 2.6 to 4.0. | 05-14-2009 |
Karel Hruska, Prague CZ
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20120255613 | PHOTOVOLTAIC CELL AND METHODS FOR PRODUCING A PHOTOVOLTAIC CELL - A photovoltaic cell ( | 10-11-2012 |
Karel Hruska, Prague 6 CZ
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20120031482 | PHOTOVOLTAIC CELL AND METHODS FOR PRODUCING A PHOTOVOLTAIC CELL - A photovoltaic device is provided that includes a substrate, a first transparent conductive layer positioned on the substrate, a plurality of transparent conductive rods positioned on the first transparent conductive layer and having a growth direction, the growth direction extending in a direction away from the substrate, a photovoltaically active layer covering the plurality of transparent conductive rods rods and a conductive layer positioned on the photovoltaically active layer. | 02-09-2012 |
Karel Hubau, Gavere BE
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20100000725 | HEAT EXCHANGER AND HEATING APPARATUS PROVIDED THEREWITH - A heat exchanger, provided with a body with at least one flue gas channel and at least one water carrying channel, at least one burner space and at least one flue gas discharge, wherein the at least one flue gas channel extends at least partly between at least a burner space and at least one flue gas discharge and at least a portion of the at least one flue gas channel comprises at least one porous or gas-transmissive heat exchange element. | 01-07-2010 |
20100242863 | METALLIC POROUS BODY INCORPORATED BY CASTING INTO A HEAT EXCHANGER - The present invention relates to a co-cast heat exchanger element intended for a central heating boiler, which heat exchanger element is made from substantially aluminum, the heat exchanger element being provided with walls which enclose a water carrying channel, and with at least one wall which encloses at least one flue gas draft to which a burner can be connected, at least one wall which encloses the at least one flue gas draft being water-cooled in that it also forms a boundary of the water-carrying channel, while one of the water-cooled walls is provided with heat exchanging surface enlarging pins and/or fins which extend in the respective flue gas draft and is also provided with other heat exchanging surface enlarging metallic porous structures. | 09-30-2010 |
Karel Karal, Oslo NO
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20100150665 | DEVICE AND METHOD FOR MARINE TOWER STRUCTURE - A tower structure ( | 06-17-2010 |
20110305523 | SUPPORT STRUCTURE FOR USE IN THE OFFSHORE WIND FARM INDUSTRY - A support structure for use in the offshore wind farm industry, and a method of manufacturing and installing same, including a foundation for installation on a seabed below a body of water and a tower connected to and extending upwards from the foundation and being capable of supporting at least an equipment unit. The foundation includes a bottom slab and a wall extending upwards from the bottom slab, thereby defining a first cavity for holding ballast and for providing buoyancy during tow-out and installation. The foundation further includes a circumferential skirt extending downwards from the bottom slab, thereby defining at least one compartment underneath the foundation. | 12-15-2011 |
Karel Klic, Oslavany CZ
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20140258990 | METHOD AND SYSTEM FOR PROVIDING A CORE DUMP-LEVEL STACK TRACE - A system and a method are disclosed for providing a core dump-level stack trace. In one example, the method includes receiving, by a processing device, a recorded state of a program, the recorded state including a base address of the program and a stack frame including an executable address for a call instruction of a function of the program; determining, by the processing device, a list of functions in view of the recorded state of the program, and creating, by the processing device, a stack trace in view of the list of functions without using debugging symbols. | 09-11-2014 |
Karel Konvicka, San Francisco, CA US
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20140256571 | Systems and Methods for Determining Copy Number Variation - A method of identifying a copy number variations reads includes mapping reads to a reference genome, computing coverage for a plurality of tiles, and normalizing the coverage for a tile based on a coverage mode across the plurality of tiles. The method further includes determining a score for the plurality of tiles being in a plurality of ploidy states, determining a maximum score path across the tiles and through the ploidy states, and providing a copy number determination based on the maximum score path. | 09-11-2014 |
Karel Koreny, Ostrava-Poruba CZ
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20110123963 | Game for Teaching Financial Skills to Players - A game is disclosed which teaches a comprehensive understanding of fundamental aspects of personal (family) finances—including insurance, working with debt, investing and securing financial objectives, and which enables players to understand principles upon which significant wealth may be accumulated, and also teaches financial advisors how to organize finances of their clients. The game teaches skills concerning personal finances, including insurance, working with debt and investing, and securing financial objectives. The game also teaches the fundamental aspects of working with the cash flow one has, and it teaches players to understand principles upon which significant wealth may be accumulated. | 05-26-2011 |
Karel Kranda, Berlin DE
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20110124600 | Use of Dopamine partial agonists for treament of the restless leg syndrome and corresponding pharmaceutical preparation - Disclosed is the oral use of dopamine partial agonists and the physiologically acceptable salts thereof in order to create a pharmaceutical preparation for treating the restless legs syndrome, which effectively controls the symptoms while having a significantly smaller undesired effect of a medicament than medicaments known in prior art. | 05-26-2011 |
Karel Lavrijsen, Oud-Turnhout BE
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20120184537 | [1,4]-BENZODIAZEPINES AS VASOPRESSIN V2 RECEPTOR ANTAGONISTS - The invention relates to a novel class of [1,4]-benzodiazepine derivatives, processes for their preparation, intermediates usable in these processes, and pharmaceutical compositions containing the compounds. Other aspects of the invention are directed to the use of said [1,4]-benzodiazepine derivatives in therapy based on the capability of said compounds to interfere with the binding of the peptide hormone, vasopressin, to its receptors. In particular as vasopressin V2 receptor antagonists and therefore useful for treating involving increased vascular resistance, cardiac insufficiency, and water retention. | 07-19-2012 |
Karel Lemr, Olomouc CZ
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20110297820 | PSEUDACYCLIN AND METHOD OF INDICATION OF A FUNGUS PSEUDALLESCHERIA BOYDII - Pseudacyclin and method of indication of a fungus | 12-08-2011 |
Karel Masarík, Brno CZ
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20150234965 | METHOD AND AN APPARATUS FOR AUTOMATIC PROCESSOR DESIGN AND VERIFICATION - A method and a system embodying the method for automatic application-specific instruction-set processor design and verification, comprising generating programming and simulation tools in accordance with application-specific instruction-set processor specifications automatically by an Electronic Design Automation tool; generating a reference model and a hardware description of the application-specific instruction-set processor in accordance with the application-specific instruction-set processor specifications automatically by the Electronic Design Automation tool; and verifying the hardware description against the reference model is disclosed. | 08-20-2015 |
20150234966 | METHOD AND AN APPARATUS FOR AUTOMATIC GENERATION OF VERIFICATION ENVIRONMENT FOR PROCESSOR DESIGN AND VERIFICATION - A method and a system embodying the method for automatic generation of a verification environment, comprising providing a first model of an application-specific instruction-set processor; providing a second model of the application-specific instruction-set processor; and generating automatically the verification environment from the first model and the second model is disclosed. | 08-20-2015 |
Karel Mazac, Friedberg DE
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20080196831 | METHOD OF ADHESIVELY BONDING A FIRST COMPONENT TO A SECOND COMPONENT - A method of adhesively bonding a first component to a second component, which comprises a peripheral zone with which the first component is adhesively bonded in overlapping manner is provided. In such method, a) at least one body of hot-melt adhesive is adhesively bonded to the first component in such a way that it comes into contact with the peripheral zone upon adhesive bonding of the first component to the second component, b) the peripheral zone is heated locally at at least one point, at which the applied body of hot-melt adhesive comes into contact with the peripheral zone upon adhesive bonding of the first component, indirectly or directly by electromagnetic induction to a temperature above the melting temperature of the hot-melt adhesive, c) the first component is brought into contact with the peripheral zone of the second component in such a way that the body of the hot-melt adhesive comes into contact with the point of the peripheral zone heated in step b), such that the hot-melt adhesive melts at the point of contact with the peripheral zone and bonds the first component to the peripheral zone of the second component after cooling. In addition, prior to step b) or after step c) a reactive adhesive is introduced in such a way between the first and the second component that it bonds the first component to the peripheral zone of the second component, the reactive adhesive being cured or allowed to cure. | 08-21-2008 |
Karel Mittig, Caen FR
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20080288470 | Method and System for Distributed Dns Resolution - The invention concerns distributed DNS resolution of a DNS request comprising an FQDN domain name between terminal (T) and relevant parent server (SPP). The method consists in transmitting (A) a DNS request (r_DNS) to an extended intermediate relay server (SRE), and, in the absence of stored previous DNS resolution solution, inserting (B) in the request a DNS resolution extension variable (VE) to generate an extended DNS request (er_DNS), transmitting (C) the extended request to the parent server. Upon verification of the variable, searching (D) for a distributed DNS resolution agent (A_R_D), transmitting (E) an extended DNS reply EA DNS, containing the agent (A_R_D) to the relay server, executing (F) the agent to generate a DNS reply (A_DNS@IP) comprising at least the (FQDN) IP address and transmitting (G) the reply A DNS(?IP) to the terminal. The invention is applicable to DNS resolution on IP local area network or on the Internet. | 11-20-2008 |
20140189868 | METHOD FOR DETECTING INTRUSIONS ON A SET OF VIRTUAL RESOURCES - A method for detecting intrusions on a set of virtual resources in a computer system including at least one physical machine hosting the set of virtual resources. The method includes: calculating an intrusion detection itinerary defined by a sequence of virtual resources from the set, the virtual resources being integrated and arranged in the sequence on the basis of respective vulnerability criticality levels assigned to the virtual resources of the set; and carrying out an intrusion detection operation, following the calculated itinerary. | 07-03-2014 |
20140223556 | Method for Detecting Attacks and for Protection - A method is provided for attack detection and protection of a set of virtual machines in a system, which includes at least one first host server hosting said set of virtual machines. The method includes: receiving an attack detection message regarding a virtual machine, triggering a first migration of the virtual machine from the first host server toward a security system, and receiving an attack treatment message regarding the migrated virtual machine. | 08-07-2014 |
Karel Nápravník, Praha CZ
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20130314063 | Active Leakage Consuming Module for LDO Regulator - An active leakage consuming module ( | 11-28-2013 |
Karel Nápravník, Praha CZ
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20130314063 | Active Leakage Consuming Module for LDO Regulator - An active leakage consuming module ( | 11-28-2013 |
Karel Petrak, Houston, TX US
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20100137208 | INTRATUMORALLY ADMINISTERED LACTOFERRIN IN THE TREATMENT OF MALIGNANTNEOPLASMS AND OTHER HYPERPROLIFERATIVE DISEASES - The present invention relates to methods of treating a hyperproliferative disease by administering a composition of lactoferrin alone or in combination with standard anti-cancer therapies. | 06-03-2010 |
20100210510 | ORAL LACTOFERRIN IN THE TREATMENT OF SEPSIS - The present invention relates to methods of treating prophylactically or therapeutically bacteremia, sepsis, septic shock or related conditions such as ARDS by administering orally a composition of lactoferrin alone or in combination with standard therapies or metal chelators to prevent or treat the consequences of bacterially induced systemic inflammatory response syndrome. In particular it is claimed that the therapeutic use of recombinant human lactoferrin alone or in combination with metal chelators or other therapeutic interventions decreases the mortality due to bacteremia, sepsis, septic shock or related conditions such as ARDS. | 08-19-2010 |
20100215699 | LACTOFERRIN AS A RADIOPROTECTIVE AGENT - This present invention relates to the field of protecting against, or rectifying the effects of damaging ionizing irradiation. The method of treatment involves oral administration of a lactoferrin composition, alone or in combination with other treatments, both in combination with other radio-protective agents and/or the standard of care. Further, the method of treatment provides for a topical administration of lactoferrin to treat lesions caused by local damaging irradiation. | 08-26-2010 |
20110076295 | LACTOFERRIN IN THE TREATMENT OF MALIGNANT NEOPLASMS AND OTHER HYPERPROLIFERATIVE DISEASES - The present invention relates to methods of treating a hyperproliferative disease by administering a composition of lactoferrin alone or in combination with standard anti-cancer therapies. | 03-31-2011 |
20120276126 | LACTOFERRIN IN THE TREATMENT OF MALIGNANT NEOPLASMS AND OTHER HYPERPROLIFERATIVE DISEASES - The present invention relates to methods of treating a hyperproliferative disease by administering a composition of lactoferrin alone or in combination with standard anti-cancer therapies. | 11-01-2012 |
20130225477 | Oral Lactoferrin in the Treatment of Severe Sepsis - The present invention relates to lactoferrin for use in the treatment of severe sepsis. In particular, the present invention relates to methods of effectively treating sepsis, in particular, severe sepsis, by administering orally a composition of lactoferrin (LF). More particularly, the present invention relates to methods of treating prophylactically or therapeutically sepsis, in particular, severe sepsis, by administering orally a composition of lactoferrin to patients with an APACHE II score ≦25, in particular <25. | 08-29-2013 |
Karel Rohacek, Ceske Budejovice CZ
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20110085174 | METHODS AND APPARATUS FOR INVESTIGATION OF VOLUME CHANGE DYNAMICS OF PHYSIOLOGICALLY ACTIVE SAMPLES - A transversal change of the position of a measured sample surface exposed to the influence of visible radiation for example actinic light, is measured interferometrically by a reflecting target, which is in mechanical contact with the measured sample surface, and reflects a measuring beam, generated together with a reference beam by a laser source, and the transversal change of the position of the measured sample surface is detected from the phase difference of harmonic waves in the beam of interfering radiation. The device involves, for example, a special detection connection of photodetectors, a measuring unit and a basic module with a computer, the design of reflecting targets for liquid and solid samples, an optomechanical dimension transmitter and a holder of solid samples. | 04-14-2011 |
Karel Schaap, Emeryville, CA US
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20130001016 | O-RING LUBRICANT - One example embodiment includes a lubricant for installing an O-ring in a groove where the lubricant cleanroom compatible. The lubricant includes a fluorinated solvent. The lubricant also includes a fluorinated oil. | 01-03-2013 |
Karel Soete, Kalken (laarne) BE
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20080280122 | Integrating non-elongated security particles in value documents - A coherent sheet-like or tape-like product adapted to be integrated into value products or documents, includes non-elongated security particles in the form of metal particles or metal coated particles, and includes a paper or plastic compatible binder. The sheet-like or tape-like product provides a better controllable concentration of the security particles and an easy integration of the security particles into the value documents. | 11-13-2008 |
Karel Sonka, Praha CZ
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20110124600 | Use of Dopamine partial agonists for treament of the restless leg syndrome and corresponding pharmaceutical preparation - Disclosed is the oral use of dopamine partial agonists and the physiologically acceptable salts thereof in order to create a pharmaceutical preparation for treating the restless legs syndrome, which effectively controls the symptoms while having a significantly smaller undesired effect of a medicament than medicaments known in prior art. | 05-26-2011 |
Karel Srnênský, Kromeriz CZ
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20100272495 | CHALK HOLDER WITH A RESILIENT LATCH ELEMENT - A chalk holder comprising a shaft and a slide formed by a chalk receiving part with a protruding spring-mounted upper arm extending through a longitudinal guide slot and provided with a button; the receiving part ( | 10-28-2010 |
Karel Srnênský, Kromeriz CZ
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20100272495 | CHALK HOLDER WITH A RESILIENT LATCH ELEMENT - A chalk holder comprising a shaft and a slide formed by a chalk receiving part with a protruding spring-mounted upper arm extending through a longitudinal guide slot and provided with a button; the receiving part ( | 10-28-2010 |
Karel Ulbrich, Praha CZ
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20080318879 | Method for the Preparation of Polymeric Conjugates of Doxorubicin with Ph-Controlled Release of the Drug - A method for the preparation of polymeric conjugates of N-(2-hydroxypropyl)methacrylamide and a methacryloylaminoacylhydrazone of doxorubicin with pH-controlled release of the drug, comprising the following three steps of synthesis: a. preparation of a monomeric methacryloylaminoacylhydrazine, wherein the aminoacyl is derived from an amino acid or oligopeptide, by reaction of a methacryloyl halide with the respective peptide, amino acid, or a derivative thereof, and subsequent hydrazinolysis, b. synthesis of a polymeric precursor by direct copolymerization of N-(2-hydroxypropyl)methacrylamide with the methacryloylaminoacylhydrazine, and c. binding of doxorubicin to the polymeric precursor by reaction thereof with doxorubicin hydrochloride. | 12-25-2008 |
20090306004 | GRAFTED MACROMOLECULAR CONJUGATES OF DOXORUBICIN WITH ANTICANCER ACTIVITY AND METHOD OF THEIR PREPARATION - A polymeric drug, in which a cancerostatic connected via spacers containing hydrolytically cleavable hydrazone bonds is bound to a water-soluble polymeric carrier prepared on the basis of a N-(2-hydroxypropyl)methacrylamide copolymer, wherein the structure of the polymeric drug consists of the main chain of N-(2-hydroxypropyl)methacrylamide carrying the cancerostatic and another chain of N-(2-hydroxypropyl)methacrylamide—a graft, which may also carry a cancerostatic, said grafts being bound to the main chain by a bond that is stable in the body and/or by a bond cleavable in the body, especially by an oligopeptide spacer selected from the series of GlyLeuGly, GlyPheGly, GlyPheLeuGly and GlyLeuPheGly, and a method of its preparation. | 12-10-2009 |
20100190928 | POLYMERIC CONJUGATES OF DOXORUBICIN WITH PH-REGULATED RELEASE OF THE DRUG AND A METHOD OF PREPARING - A polymeric drug in the form of a conjugate of a copolymer of N-(2-hydroxypropyl)-methacrylamide (HPMA) with doxorubicin bound to the polymer via spacers containing hydrolytically cleavable hydrazone bonds, of formula (I), wherein SP | 07-29-2010 |
20120296048 | Dendritic High-molecular-weight Polymer Drug Carriers and Their Conjugates with Drugs Especially for Treatment of Solid Tumours - The present invention relates to water-soluble high-molecular-weight polymer drug carriers and their conjugates with drugs, derived from dendrimers of the amidoamine and 2,2-bis(hydroxymethyl)propanoic types, the amino and hydroxy end groups of which are attached to semitelechelic copolymers of N-(2 hydroxypropyl)methacrylamide (HPMA) through biodegradable spacers. The polymer carriers and conjugates enable targeted transport notably of anticancer drugs into solid tumors in which biodegradation, the associated controlled drug release and subsequent elimination of polymer carrier from the organism are provided. The polymer carrier conjugated with a cancerostatic for use in targeted therapy of human tumors. | 11-22-2012 |
Karel Vales, Zbraslav CZ
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20130338383 | PREGNANOLONE DERIVATIVES SUBSTITUTED IN 3ALPHA-POSITION WITH THE CATIONIC GROUP, METHOD OF THEIR PRODUCTION, USAGE AND PHARMACEUTICAL PREPARATION INVOLVING THEM - Pregnanolone derivatives, substituted in 3 alpha-position with the cationic group, of general formula I, and a method of the production of these compounds and their utilization for treatment of neuropsychiatric disorders related to imbalance of glutamatergic neurotransmitter system, such as ischemic damage of CNS, neurodegenerative changes and disorders of CNS, affective disorders, depression, post traumatic stress disorder, and other diseases related to stress, anxiety, schizophrenia, and psychotic disorders, pain, addictions, multiple sclerosis, epilepsy, and gliomas. The compounds are also used for production of veterinary and human pharmaceutical preparation for treatment of above mentioned diseases and for production of pharmaceutical preparations containing these compounds. | 12-19-2013 |
Karel Vales, Praha CZ
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20120071453 | STEROIDE ANIONIC COMPOUNDS, METHOD OF THEIR PRODUCTION, USAGE AND PHARMACEUTICAL PREPARATION INVOLVING THEM - A compound with general formula I | 03-22-2012 |
Karel Vanackere, Knokke-Heist BE
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20110100028 | APPARATUS AND METHOD FOR CRYOGRANULATING A PHARMACEUTICAL COMPOSITION - Cryogranulation systems with improved dispenser assemblies are provided for use in manufacturing frozen pellets of pharmaceutical substances in a fluid medium. Methods of cryogranulating the pharmaceutical substance in the fluid medium are also provided. In particular embodiments, the dispenser assembly is used with suspensions or slurries of pharmaceutical compositions including biodegradable substances, such as proteins, peptides, and nucleic acids. In certain embodiments, the pharmaceutical substance can be adsorbed to any pharmaceutically acceptable carrier particles suitable for making pharmaceutical powders. In one embodiment, the pharmaceutical carrier can be, for example, diketopiperazine-based microparticles. The dispenser assembly improves the physical characteristics of the cryopellets formed and minimizes product loss during processing. | 05-05-2011 |
20140044790 | APPARATUS AND METHOD FOR CRYOGRANULATING A PHARMACEUTICAL COMPOSITION - Cryogranulation systems with improved dispenser assemblies are provided for use in manufacturing frozen pellets of pharmaceutical substances in a fluid medium. Methods of cryogranulating the pharmaceutical substance in the fluid medium are also provided. In particular embodiments, the dispenser assembly is used with suspensions or slurries of pharmaceutical compositions including biodegradable substances, such as proteins, peptides, and nucleic acids. In certain embodiments, the pharmaceutical substance can be adsorbed to any pharmaceutically acceptable carrier particles suitable for making pharmaceutical powders. In one embodiment, the pharmaceutical carrier can be, for example, diketopiperazine-based microparticles. The dispenser assembly improves the physical characteristics of the cryopellets formed and minimizes product loss during processing. | 02-13-2014 |
Karel Van Eenooghe, Aalter BE
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20130042437 | WIRE PROFILE FOR CARD CLOTHING - A wire profile for card clothing comprising a rib portion and plurality of teeth over the length of said rib portion, wherein said teeth are sloped with back slope representing the backbone of said teeth and front slope representing the side in direct contact with fibre, said back slope having a tangent forming a back angle with the rib portion, said front slope being divided into at least two segments, a tip segment converging with the said back slope to form a tip of said teeth and said tip segment serving to penetrate between fibres, said tip segment having a tangent forming a tip angle with the rib portion, and an undercut segment to retain the fibres, said undercut having a tangent forming an undercut angle with the rib portion, said undercut angle being at each point in the undercut segment greater than the maximum of the back angle and being smaller than the smallest value of the tip angle. | 02-21-2013 |
Karel Vanek, Mnisek Pod Brdy CZ
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20160122975 | TAILGATE - An attachment system for attaching a tailgate to a frame of a power machine. The tailgate is moveable between a closed position and an opened position. The attachment system includes first and second attachment structures for pivotally mounting the cover to the frame. The second attachment structure is spaced apart from the first attachment structure. A connection member connects the first attachment structure and the second attachment structure. The tailgate is configured to pivot about the connection member as it moves between the closed position and the open position. | 05-05-2016 |
20160122978 | MECHANICAL LINKAGE FOR CONTROL OF POWER MACHINE - A mechanical linkage for a power machine includes first and second horizontal shafts extending sideways along respective first and second axes. First and second links are operably coupled to the respective first and second horizontal shafts. The links convert actuation of operator input devices of the power machine into rotation of the horizontal shafts about their axes. First and second valve actuators convert rotation of the respective first and second horizontal shafts into actuation of respective first and second spools in a hydraulic valve of the power machine. | 05-05-2016 |
Karel Vanek, Prague CZ
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20090230710 | REAR ACCESSIBLE SERVICE HATCH - A zero tail swing construction vehicle includes a body, a pair of track assemblies for supporting the body for movement over a surface, an engine supported on the body for providing power, a lower attachment pivotably coupled to the body, an upper attachment pivotably coupled to the body, a hydraulic system for providing power to the lower attachment and the upper attachment, an operator support pivotably coupled to the body and a rear hatch coupled to the operator support. The operator support is pivotable from a usage position forward about a horizontal axis to a service position. The rear hatch is pivotable with the operator support from the usage position to the service position. The construction vehicle further includes a plurality of service check points located underneath the operator support in the usage position. In the usage position the rear hatch conceals the service check points, while in the service position service check points are accessible through an opening. | 09-17-2009 |
Karel Vanheusden, Placitas, NM US
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20100112195 | METHOD FOR THE FABRICATION OF CONDUCTIVE ELECTRONIC FEATURES - Precursor compositions in the form of a tape that can be transferred to a substrate and converted to an electronic feature at a relatively low temperature, such as not greater than about 200° C. The tape composition can be disposed on a carrier to form a ribbon structure that is flexible and can be handled in a variety of industrial processes. | 05-06-2010 |
Karel Vanheusden, Santa Clara, CA US
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20090014423 | CONCENTRIC FLOW-THROUGH PLASMA REACTOR AND METHODS THEREFOR - The present invention provides a radiofrequency plasma apparatus for the production of nanoparticles and method for producing nanoparticles using the apparatus. The apparatus is designed to provide high throughput and makes the continuous production of bulk quantities of high-quality crystalline nanoparticles possible. The electrode assembly of the plasma apparatus includes an outer electrode and a central electrode arranged in a concentric relationship to define an annular flow channel between the electrodes. | 01-15-2009 |
20130092525 | CONCENTRIC FLOW-THROUGH PLASMA REACTOR AND METHODS THEREFOR - The present invention provides a radiofrequency plasma apparatus for the production of nanoparticles and method for producing nanoparticles using the apparatus. The apparatus is designed to provide high throughput and makes the continuous production of bulk quantities of high-quality crystalline nanoparticles possible. The electrode assembly of the plasma apparatus includes an outer electrode and a central electrode arranged in a concentric relationship to define an annular flow channel between the electrodes. | 04-18-2013 |
Karel Vanstraelen, Alken BE
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20130298332 | MOTORIZED BED BASE, SLAT MODULE AND BED - The invention relates to a bed base ( | 11-14-2013 |
Karel Vergote, Landen BE
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20150059913 | EXHAUST PIPE - The exhaust pipe comprises an inlet pipe, an outlet pipe and a bend portion arranged between the inlet pipe and the outlet pipe. The bend portion comprises an inlet bend and an outlet bend, wherein a central bend portion defines an intermediate section of inlet bend and outlet bend and wherein the inlet bend and the outlet bend each cover 50 percent of the total bend angle covered by the bend portion. The central bend portion comprises a diameter, which is smaller than a diameter of the inlet bend and of the outlet bend in a bending plane. In addition a bend radius R of the bend portion varies along the bend portion such that a bend radius of the inlet bend is larger than a bend radius of the outlet bend. | 03-05-2015 |
Karel Vincke, Oedelem BE
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20090107206 | ARRANGEMENT FOR PROCESSING SHEET METAL - A mechanical arrangement for processing sheet metal includes a sheet metal processing device, a transport device configured to position a sheet metal workpiece relative to the sheet metal processing device, the transport device including at least one workpiece carrier that is movable along a transport path that extends along a first transport line and a second transport line, and at least two X-guides and at least two Y-guides, the X-guides arranged parallel with the first transport line and the Y-guides arranged parallel with the second transport line. The at least two X-guides and the at least two Y-guides are configured to be coupled to each other by a transfer device to form a transport course, the workpiece carrier circulates along the X-guides and the Y-guides, and the transfer device is configured to move the workpiece carrier from one of the X-guides to one of the Y-guides. | 04-30-2009 |
20090184097 | WORKPIECE SUPPORT CLEANING - A mechanical apparatus maintains and/or cleans support strips of a workpiece support that forms a support plane for supporting workpieces. The mechanical apparatus includes a transport device for moving the workpiece support along a transport axis X and a service device that has a tool for processing the support strips. The service device is movable by means of a mechanical movement unit along a movement axis Y that is arranged at an angle relative to the transport axis X and/or along a movement axis Z that is arranged at an angle relative to the transport axis X and that is different from the movement axis Y, with the movement of the workpiece support along the transport axis X and the movement of the service device along the movement axis Y and/or along the movement axis Z being controllable in a coordinated manner by means of a control unit. | 07-23-2009 |
20110024401 | Recovery of Energy from a Laser Machining System - A method for the recovery of energy from a laser machining system and a device for performing the same, in which the method includes operating the laser machining system and generating thermal energy having a maximum temperature T | 02-03-2011 |
Karel Vinckier, Deurle BE
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20130080122 | METHOD, COMPUTER PROGRAM PRODUCT AND APPARATUS FOR PROVIDING A MODEL MAP FOR WORKFLOW INTEGRATION - A method, apparatus and computer program product are described for providing a model map for workflow integration from concept to production. The apparatus may receive a file in a first format, produce a mapped file from the file in the first format, and provide for conversion of the mapped file from the mapped format to a second, different format. The file in the first format may be supported by a first application, such as an architectural design application, a design engineering application, or a production specific application. The file in the second format may be supported by a second application, which may include an architectural design application, a design engineering application, or a production specific application. In this way, a file in the first format that is only operable on the first application may be converted to a file in the second format that is operable on the second application. | 03-28-2013 |
Karel Vit, Gossau DE
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20090218400 | Method for optimising the firing trigger of a weapon or artillery - The invention relates to a method for determining a favourable moment for triggering the firing of a weapon on a moving target. According to said method, firing commands and expected impact points (P | 09-03-2009 |
Karel Volenec, Hradec Králové CZ
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20120116492 | MEDICAL DEVICE - A medical device includes yarns made of a shape memory material and polymer yarns, wherein the yarns made of said shape memory material include polymer sheathing. | 05-10-2012 |
Karel Zadrobilek, Hradec Kralove CZ
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20160029995 | HEMODYNAMIC MONITORING DEVICE AND METHODS OF USING SAME - Hemodynamic monitoring systems and methods are disclosed including a device comprising a first sensor configured to measure a velocity of blood flow in an adjacently-located portion of a superior vena cava of a mammalian patient using ultrasound waves; a second sensor configured to measure respiratory cycle data of the mammalian patient; and a computer configured to process the measured velocity of blood flow and the measured respiratory cycle data to provide hemodynamic parameters corresponding to the mammalian patient. | 02-04-2016 |
Karel Zuiderveld, Minnetonka, MN US
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20120092476 | METHODS AND APPARATUS TO FORM A WAVELET REPRESENTATION OF A PATHOLOGY SLIDE HAVING GLASS AND TISSUE REGIONS - Example methods, apparatus and articles of manufacture to form a wavelet representation of a pathology slide having glass and tissue regions are disclosed. A disclosed example method includes capturing a digital image of a pathology slide, identifying a portion of the digital image that represents a glass portion of the slide, and storing a value representing that the wavelet coefficients for the identified glass portion of the slide are unused without computing a wavelet transform for the identified glass portion. | 04-19-2012 |
Karel Zuzak, Arlington, TX US
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20080306337 | Characterization of a Near-Infrared Laparoscopic Hyperspectral Imaging System for Minimally Invasive Surgery - The present invention includes an apparatus and methods for use of a hyperspectral surgical laparoscope that includes an illuminated laparoscope; a liquid crystal tunable filter generally center-mounted on the laparoscope and positioned to collect back-reflected light from a target; a relay lens generally center-mounted on the laparoscope to focus light from the liquid crystal tunable filter; and a focal plane array generally center-mounted on the laparoscope, wherein light that is reflected from the target is imaged on the focal plane array and captured as a digital data cube. | 12-11-2008 |
20100056928 | DIGITAL LIGHT PROCESSING HYPERSPECTRAL IMAGING APPARATUS - A hyperspectral imaging system having an optical path. The system including an illumination source adapted to output a light beam, the light beam illuminating a target, a dispersing element arranged in the optical path and adapted to separate the light beam into a plurality of wavelengths, a digital micromirror array adapted to tune the plurality of wavelengths into a spectrum, an optical device having a detector and adapted to collect the spectrum reflected from the target and arranged in the optical path and a processor operatively connected to and adapted to control at least one of: the illumination source; the dispersing element; the digital micromirror array; the optical device; and, the detector, the processor further adapted to output a hyperspectral image of the target. The dispersing element is arranged between the illumination source and the digital micromirror array, the digital micromirror array is arranged to transmit the spectrum to the target and the optical device is arranged in the optical path after the target. | 03-04-2010 |