Marta
Marta Abad Collado, Alicante ES
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20090317483 | Bicomponent Bioadhesive for Biomedical Use - The invention relates to new biocomponent bioadhesive formulations, with a synthetic part and an autologous biological part of blood origin comprising plasma rich in platelets and in growth factors, and its use of same in biomedicine, preferably in opththalmic surgery. | 12-24-2009 |
Marta Altuna Urquijo, Barcelona ES
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20090124647 | Indole Derivatives as Antitumoral Compounds - Antitumoural compounds of general formula (I); wherein Ar is an heterocyclic group of formula (a) and R | 05-14-2009 |
20100048596 | Indole Derivatives as Antitumoral Compounds - Antitumoural compounds of general formula (I); wherein Ar is an heterocyclic group of formula (a) and R | 02-25-2010 |
Marta Alves Da Silva, Ponte De Lima PT
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20110159057 | HYDROXYAPATITE AND BIOGLASS-BASED PELLETS, PRODUCTION PROCESS AND APPLICATIONS OF THEREOF - The disclosed subject matter refers to hydroxyapatite and bioglass-based pellets of homogeneous size and spherical shape, whose interconnective porous structure, in the micrometer range, allows for an enhanced osteoconductivity and osteointegration, with specific application as a synthetic bone graft and to the respective production process. The production process is based on the pharmaceutical technology of extrusion and spheronization employing a porogenic agent and applying a sinterization stage in the presence of a vitreous liquid phase, which reverts on behalf of a higher reproducibility, superior yield and greater production capacity. Therefore, the disclosed subject matter is directed to the production of hydroxyapatite and bioglass-based pellets with applications in osteoregenerative medicine, particularly in the fields of orthopaedic surgery, maxillofacial surgery, dental surgery, implantology and as tissue engineering scaffolds | 06-30-2011 |
Marta Angelet Subirats, Jorge Girona Salgado Barcelona ES
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20090203781 | N-N-Acyloxypropyl Lysine Methyl Ester-and N,N-Bis(N-Acyloxypropyl) Lysine Methyl Ester-Type Compounds and Use Thereof as Surface-Active Agents with an Antimicrobial Activity - The invention relates to novel compounds having an amphiphilic character (cationic, anionic, amphoteric and non-ionic), derivatives of n acyloxypropyl-type lysine amino acid according to general formula (I), which are intended to be used in the food, pharmaceutical and cosmetic industries as surface-active agents having a self-aggregating capacity and antimicrobial properties. Variations in activity are a function of the ionic nature of the final molecule, the number of fatty chains and the length thereof. The aforementioned products are prepared using a chemical synthesis method. The intermediate and final products are purified by means of liquid/liquid and liquid/solid extractions, crystallisations, cationic exchange chromatography and normal phase chromatography. | 08-13-2009 |
Marta Ayala Avila, Ciudad De La Habana CU
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20090312190 | Methods and Proteins for the Prophylactic and/or Therapeutic Treatment of Four Serotypes of Dengue Virus and Other Flaviviruses - The present invention is related to the field of the pharmaceutical industry, and describes a conserved area on the surface of the E protein that can be used for the development of wide-spectrum antiviral molecules to be employed in the prophylaxis and/or treatment of infections due to Dengue Virus serotypes 1-4 and other flaviviruses. The invention also covers chimeric proteins to be used as vaccines or as a prophylactic or therapeutic treatment against the four serotypes of Dengue Virus and other flaviviruses. | 12-17-2009 |
20100151566 | RECOMBINANT ANTIBODIES AGAINST THE VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) - The present invention deals with recombinant polypeptide molecules related to antibodies, that specifically recognize the human Vascular Endothelial Growth Factor A (VEGF-A), and interfere with its in vitro stimulatory effects and pro-angiogenic activity in vivo. These recombinant polypeptide molecules affect proliferation of human endothelial cells in vitro, subcutaneous angiogenesis in mice induced by Matrigel pellets that contain VEGF-A and the growth of human tumors transplanted in nude athymic mice. Several of these moleculas prevent choroideal neovascularization in a non human primate experimental model. These molecules can be employed for passive immunotherapy in pathological entities which have in its base an abnormal increase in blood vessels, as: age-related macular degeneration (wet variant), cancer and its metastases, neovascular glaucoma, diabetic and newborn retinopathies, acute and chronic inflammatory processes, infectious diseases, autoimmune diseases, organ transplant rejection, hemangioma, angiofibroma, and others. | 06-17-2010 |
Marta Barrachina Castillo, Pozuelo De Alarcon (madrid) ES
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20080206762 | Method for the Diagnosis of Alzeimer's Disease - The invention relates to a method for the diagnosis and/or prognosis of Alzheimer's disease, consisting in determining the expression level of a gene encoding a lysosomal marker. | 08-28-2008 |
Marta Betcke, London GB
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20110091007 | System and Method for Image Reconstruction by Using Multi-Sheet Surface Rebinning - The present application is directed toward the generation of three dimensional images in a tomography system having X-ray sources offset from detectors, in particular in a system where the sources are located on a plane, while detectors are located on multiple parallel planes, parallel to the plane of sources and all the planes of detectors lie on one side of the plane of sources. A controller operates to rebin detected X-rays onto a non-flat surface, perform two dimensional reconstruction on the surface, and generate the three dimensional image from reconstructed images on the plurality of surfaces. | 04-21-2011 |
20120207374 | System and Method for Image Reconstruction By Using Multi-Sheet Surface Rebinning - The present application is directed toward the generation of three dimensional images in a tomography system having X-ray sources offset from detectors, in particular in a system where the sources are located on a plane, while detectors are located on multiple parallel planes, parallel to the plane of sources and all the planes of detectors lie on one side of the plane of sources. A controller operates to rebin detected X-rays onto a non-flat surface, perform two dimensional reconstruction on the surface, and generate the three dimensional image from reconstructed images on the plurality of surfaces. | 08-16-2012 |
Marta Bianciardi, Rome IT
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20090080725 | METHODS USING RECURRENCE QUANTIFICATION ANALYSIS TO ANALYZE AND GENERATE IMAGES - Methods for identifying and quantifying recurrent and deterministic patterns in digital images are provided. The methods, which are based on Recurrence Quantification Analysis (RQA), generate similarity or dissimilarity distance matrices for digital images that may be used to calculate a variety of quantitative characteristics for the images. Also provided are methods for identifying and imaging spatial distributions of time variable signals generated from dynamic systems. In these methods a time variable signal is recorded for a plurality of area or volume elements into which a dynamic system has been sectioned and RQA is used to calculate one or more RQA variables for each of the area or volume elements, which may then be used to generate a two or three dimensional image displaying the spatial distribution of the RQA variables across the system. | 03-26-2009 |
Marta Bucciolini, Firenze IT
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20100176302 | Bidimensional dosimetric detector - Bidimensional dosimetric detector, comprising: a monolithic base-matrix ( | 07-15-2010 |
Marta Carrascal Riera, Barcelona ES
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20090029996 | Pyridazin-3(2H)-One Derivatives And Their Use As Pde4 Inhibitors - The invention relates to new therapeutically useful pyridazin-3(2H)-one derivatives, to processes for their preparation and to pharmaceutical compositions containing them. These compounds are potent and selective inhibitors of phosphodiesterase 4 (PDE4) and are thus useful in the treatment, prevention and suppression of related pathological conditions, diseases and disorders, in particular asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, topic dermatitis, psoriasis or irritable bowel disease. | 01-29-2009 |
20110274657 | OXADIAZOLE DERIVATIVES AS S1P1 RECEPTOR ANTAGONISTS - The present disclosure relates to oxadiazole derivatives of formula (I) as well as pharmaceutical compositions comprising them, and their use in therapy as agonists of the S1P1 receptor. | 11-10-2011 |
20110311485 | 1,2,4-OXADIAZOLE DERIVATIVES AND THEIR THERAPEUTIC USE - The present disclosure relates to 1, 2, 4 oxadiazole derivatives of formula (I) as well as pharmaceutical compositions comprising them, and their use in therapy as agonists of the S1P1 receptors. | 12-22-2011 |
20140163033 | PYRROLOTRIAZINONE DERIVATIVES AS P13K INHIBITORS - New pyrrolotriazinone derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks). | 06-12-2014 |
Marta Carrascal Riera, Barcelona IT
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20090111819 | NEW PYRIDAZIN-3(2H)-ONE DERIVATIVES - Pyridazin-3(2H)-one derivatives of formula (I) are found to inhibit PDE-4: | 04-30-2009 |
20100204241 | NEW PYRIDAZIN-3(2H)-ONE DERIVATIVES - Pyridazin-3(2H)-one derivatives of formula (I) are found to inhibit PDE-4: | 08-12-2010 |
Marta Castillo Franco, Bascharage LU
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20090129628 | METHOD FOR DETERMINING THE POSITION OF AN OBJECT FROM A DIGITAL IMAGE - Method for determining the position of an object point in a scene from a digital image thereof acquired through an optical system is presented. The image comprises a set of image points corresponding to object points and the position of the object points are determined by means of predetermined vectors associated with the image points. The predetermined vector represents the inverted direction of a light ray in the object space that will produce this image point through the optical system comprising all distortion effects of the optical system. | 05-21-2009 |
20110018967 | RECORDING OF 3D IMAGES OF A SCENE - A method of recording 3D images of a scene based on the time-of-flight principle comprises illuminating a scene by emitting light carrying an intensity modulation, imaging the scene onto a pixel array using an optical system, detecting, in each pixel, intensity-modulated light reflected from the scene onto the pixel and determining, for each pixel, a distance value based on the phase of light detected in the pixel. The determination of the distance values comprises a phase-sensitive de-convolution of the scene imaged onto the pixel array such that phase errors induced by light spreading in the optical system are compensated for. | 01-27-2011 |
Marta Castillo Garcia, Burgos ES
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20090122509 | WIRING SYSTEM WITH INTEGRATED ELECTRONICS - Wiring system which comprises: a flexible printed circuit board ( | 05-14-2009 |
Marta Cavero-Tomas, Wayland, MA US
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20090118220 | SUBSTITUTED ADENINES AND THE USES THEREOF - This invention relates to compounds of Formula I: | 05-07-2009 |
Marta Cavero-Tomas, West Roxbury, MA US
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20090048203 | SUBSTITUTED ADENINES AND THE USES THEREOF - This invention relates to compounds of Formula (I): and their use in the treatment of bacterial infections. | 02-19-2009 |
Marta Corselli, Limhamn SE
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20090162434 | MESALAZINE TABLET - Disclosed are mesalazine tablets and a method for their preparation. The mesalazine tablets comprise a tablet core, a first coating layer, and a second coating layer. The tablet core comprises mesalazine; the first coating layer comprises a cellulose derivative and/or povidone, and the second coating layer comprises methacrylic acid/methyl methacrylate copolymer and an anti-tack agent. The tablets show a high degree of uniformity and reproducibility and release mesalazine starting at pH 6.8 and are used in the treatment of colorectal diseases. | 06-25-2009 |
Marta Cortes-Cros, Basel CH
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20100143362 | LINGO binding molecules and Pharmaceutical Use Thereof - The present invention provides a binding molecule which is capable of binding to the rat, cynomolgus monkey and human LINGO polypeptide, a polynucleotide encoding such binding molecule; an expression vector comprising said polynucleotide; an expression system comprising a polynucleotide capable of producing a binding molecule; an isolated host cell which comprises an expression system as defined above; the use of such binding molecule as a pharmaceutical, especially in the treatment to promote axonal regeneration/plasticity; a pharmaceutical composition comprising said binding molecule; and a method of treatment of diseases associated with axonal degeneration and demyelination. | 06-10-2010 |
20130071400 | LINGO binding molecules and Pharmaceutical Use Thereof - The present invention provides a binding molecule which is capable of binding to the rat, cynomolgus monkey and human LINGO polypeptide, a polynucleotide encoding such binding molecule; an expression vector comprising said polynucleotide; an expression system comprising a polynucleotide capable of producing a binding molecule; an isolated host cell which comprises an expression system as defined above; the use of such binding molecule as a pharmaceutical, especially in the treatment to promote axonal regeneration/plasticity; a pharmaceutical composition comprising said binding molecule; and a method of treatment of diseases associated with axonal degeneration and demyelination. | 03-21-2013 |
20140037639 | LINGO Binding Molecules and Pharmaceutical Use Thereof - The present invention provides a binding molecule which is capable of binding to the rat, cynomolgus monkey and human LINGO polypeptide, a polynucleotide encoding such binding molecule; an expression vector comprising said polynucleotide; an expression system comprising a polynucleotide capable of producing a binding molecule; an isolated host cell which comprises an expression system as defined above; the use of such binding molecule as a pharmaceutical, especially in the treatment to promote axonal regeneration/plasticity; a pharmaceutical composition comprising said binding molecule; and a method of treatment of diseases associated with axonal degeneration and demyelination. | 02-06-2014 |
20140255415 | LINGO Binding Molecules and Pharmaceutical Use Thereof - The present invention provides a binding molecule which is capable of binding to the rat, cynomolgus monkey and human LINGO polypeptide, a polynucleotide encoding such binding molecule; an expression vector comprising said polynucleotide; an expression system comprising a polynucleotide capable of producing a binding molecule; an isolated host cell which comprises an expression system as defined above; the use of such binding molecule as a pharmaceutical, especially in the treatment to promote axonal regeneration/plasticity; a pharmaceutical composition comprising said binding molecule; and a method of treatment of diseases associated with axonal degeneration and demyelination. | 09-11-2014 |
Marta Dabros, Worcester, MA US
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20110009623 | SELECTIVE GROWTH OF STABLE POLYMORPHS - Methods and an apparatus for producing stable crystal polymorphs are provided. Inner surfaces of glass vials with a concave bottom topography are coated with nonstick compounds to select for nucleation of stable polymorphs. | 01-13-2011 |
Marta De La Cruz Garcia, Zurich CH
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20110179800 | METHOD FOR OPERATING A GAS TURBINE AND GAS TURBINE - A gas turbine ( | 07-28-2011 |
20110289899 | COMBINED CYCLE POWER PLANT WITH FLUE GAS RECIRCULATION - An exemplary method for the operation of a CCPP with flue gas recirculation to reduce NOx emissions and/or to increase the CO2 concentration in the flue gases to facilitate CO2 capture from the flue gases as well as a plant designed to operate is disclosed. To allow a high flue gas recirculation ration (rFRG) an imposed combustion inhomogeneity ratio (ri) is used for flame stabilization. The imposed combustion inhomogeneity ratio (ri) is controlled as function of the flue gas recirculation rate (rFRG) and/or combustion pressure. Oxygen or oxygen enriched air to the gas turbine inlet gases or to the combustor is admixed to enhance operatability. | 12-01-2011 |
Marta Drewniak, Carrollton, TX US
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20080254308 | MULTILAYERED POLYMERIC STRUCTURE AND METHODS - Multilayered structures formed from two or more polymeric layers are fabricated to obtain a single structure preferably having advantages of each of the separate layers. Polyolefin-based substrates can provide a layer with a good balance of stiffness and impact resistance, excellent processability, and relatively lower cost. Tie layers, preferably physically positioned adjacent a polyolefin-based substrate layer, facilitates adhering additional layer(s) together with the polyolefin-based substrate. Suitable tie layers generally include a multicomponent blend of at least one vinyl cyanide-containing component and at least one styrenic block copolymer component. Preferably, the additional layers include at least one acrylate-based cap layer, which can have a glossy, scratch resistance outer layer with excellent optical characteristics. | 10-16-2008 |
Marta Dziechciarkova, Olomouc CZ
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20110014637 | Method For Determining The Sensitivity Of Patients Suffering From A Cancer Disease To Biological Therapy - The invention relates to a method for determining the sensitivity of patients suffering from a cancer disease towards targeted biological therapy based on the inhibition of signaling pathways of the members of HER family (e.g., HER-1, HER-2, HER-3 and HER-4) by determining the expression of the biomarker S6 kinase or its post-translationally modified form or of the biomarkers of the activation of S6 kinase or their post-translationally modified forms in the tumor. | 01-20-2011 |
Marta Ecija Queralt, Barcelona ES
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20090124577 | Intermediate Compounds for the Preparation of an Angiotensin II Receptor Antagonist - It comprises new substituted 4-valinylmethylphenyl boronic acids of formula (II) and their derivatives and also its preparation process. It also comprises a preparation process of Valsartan (I) from such intermediates. The process comprises the reaction of the new 4-valinylmethylphenyl boronic compounds with a (halophenyl)tetrazole compound which proceeds with high yields. The process is particularly advantageous in its practical industrial realization because it avoids the use of azide derivatives and also the use of expensive biphenyl intermediates. | 05-14-2009 |
Marta Enguita Martinez, Barcelona ES
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20110070234 | NP1 ACTIVITY REGULATING ELEMENTS USEFUL FOR THE PRODUCTION OF DRUGS FOR THE TREATMENT OR PREVENTION OF HUMAN NEURODEGENERATIVE DISEASES, RESULTING DRUGS AND USE THEREOF - The invention relates to a series of compounds useful for the production of drugs or pharmaceutical compositions for the treatment or prevention of human neurological diseases, preferably neurodegenerative diseases, which inhibit the activity of the human NP1 protein which acts as an inducer of neurodegeneration and neural apoptosis. Said compounds include iRNA inhibitors of the gene expression of the NP1 gene and specific antibodies of the human NP1 protein, as well as peptides derived from same, which can be used in passive and active immunisation methods respectively against said diseases. | 03-24-2011 |
Marta Evans, Durham GB
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20090144853 | Control of Gene Expression in Plants - Disclosed is an isolated nucleic acid molecule, which molecule comprises at least 500 bases of the nucleotide sequence shown in FIG. | 06-04-2009 |
Marta Fedoryshyn, Freiburg DE
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20100221812 | PRODUCTION OF GENETICALLY MODIFIED ACTINOMYCETES BY RECOMBINATION - The present invention relates to the recombinant modification of microorganisms, in particular actinomycetes. This is effected with the use of the recombination systems Dre-rox and Cre-lox. The present invention provides novel nucleotide sequences for the recombinases of the abovementioned recombination systems. Here, synthetic genes which have the codons preferred by actinomycetes and can therefore be used in these host organisms were produced. | 09-02-2010 |
Marta Fidrich, Szeged HU
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20090022375 | SYSTEMS, APPARATUS AND PROCESSES FOR AUTOMATED MEDICAL IMAGE SEGMENTATION - A system and process for combining multiple datasets to provide a composite dataset is described. The system includes a data collection tool, a computation engine and a memory coupled to the data collection tool and computer-readable code embodied on a computer-readable medium. The computer-readable code is configured so that when the computer-readable code is executed by one or more processors associated with the computation engine the computer-readable code causes the one or more processors to: (i) accept two or more datasets corresponding to distinct measurements of a subject, (ii) initiate processing of the two or more datasets, (iii) contemporaneously segment and register a combination of the two or more datasets to achieve a combined dataset, (iv) test for convergence of the combined dataset and (v) provide the combined dataset for analysis when the test for convergence indicates that the combined dataset has been registered and segmented. | 01-22-2009 |
20090097726 | SYSTEMS, METHODS AND APPARATUS AUTOMATIC SEGMENTATION OF LIVER IN MULTIPHASE CONTRAST-ENHANCED MEDICAL IMAGES - Systems, method and apparatus in which some embodiments of automatic segmentation of a liver parenchyma from multiphase contrast-enhanced computed-tomography images includes analyzing an intensity change in the images belonging to the different phases in order to determine the region-of-interest of the liver, thereafter segmenting starting from the region-of-interest and incorporating anatomical information to prevent oversegmentation, and thereafter combining the information of all available images. | 04-16-2009 |
20100128946 | SYSTEMS, APPARATUS AND PROCESSES FOR AUTOMATED MEDICAL IMAGE SEGMENTATION USING A STATISTICAL MODEL - A system and process for analyzing multidimensional data characterizing a least a portion of a subject is described. An input module accepts at least one multidimensional dataset which is derived from any of several types of data sources. A registration module accepts the dataset from the input module and registers the dataset from the input module to a selected anatomical model to provide a registered dataset. A processing module is coupled to the registration module and uses this in determining a core region and associated core region information, and computes threshold characteristics of the registered dataset. A segmentation module accepts the registered dataset and the core region information from the processing module, and segments the registered dataset to provide a segmented description of an organ from the registered dataset and core region information, where the segmented, registered dataset describes characteristics of the organ of the subject. | 05-27-2010 |
20130083987 | SYSTEM AND METHOD FOR SEGMENTING BONES ON MR IMAGES - A method for segmenting bones on magnetic resonance (MR) images includes retrieving an MR image and performing an enhancement process on the MR image to generate a bone enhanced MR image. The bone enhanced MR image is then registered to a computer tomography (CT) based bone atlas. An MR image with bone segmentation is generated by segmenting the bone enhanced MR image using the CT based bone atlas as a mask. The MR image with bone segmentation may be presented on a display. | 04-04-2013 |
20130121552 | SYSTEM AND METHOD FOR AUTOMATIC SEGMENTATION OF ORGANS ON MR IMAGES - A method for segmenting organs on magnetic resonance (MR) images includes retrieving an MR image of a subject and generating a transformation matrix by segmenting bones on the MR image. An initial organ segmentation of the MR image is generated by registering a combined organ and bone atlas with the MR image using the transformation matrix. The MR image with initial organ segmentation may be shown on a display. | 05-16-2013 |
20130188846 | METHOD, SYSTEM AND COMPUTER READABLE MEDIUM FOR AUTOMATIC SEGMENTATION OF A MEDICAL IMAGE - A method for automatic segmentation of a medical image is provided. The method comprises registering a reference image associated with an object to the medical image, determining a transformation function on the basis of the registration, applying the transformation function to a probability map associated with the object; carrying out a probability thresholding on the transformed probability map by selecting a first area of the medical image in which the probability of the object is within a probability range, carrying out an intensity thresholding on the medical image by selecting a second area of the medical image in which the intensity is within an intensity range, selecting a common part of the first and second areas and carrying out on the common part a morphological opening resulting in separate sub-areas, selecting the largest sub-area as a seed, and segmenting the medical image on the basis of the seed. | 07-25-2013 |
20140029831 | SYSTEMS AND METHODS FOR PERFORMING SEGMENTATION AND VISUALIZATION OF MULTVARIATE MEDICAL IMAGES - A method for generating an image includes obtaining a first image and a second image of an object of interest, generating a joint histogram using the first and second images, transforming the information in the histogram from histogram space to image space using a look-up table, and generating a color image using the information output from the look-up table. A system and non-transitory computer readable medium are also described herein. | 01-30-2014 |
Marta Fondrodona Turon, Basel CH
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20110004004 | PYRROLOPYRROLE DERIVATIVES, THEIR MANUFACTURE AND USE - The present invention relates to compounds of the formula (I) wherein the substituents are as defined in claim | 01-06-2011 |
Marta Garcia Diez, Madrid ES
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20090070889 | MOUSE MODEL COMPRISING AN ENGRAFTED HUMAN SKIN HAVING HYPERSENSITIVITY TO UV-LIGHT - The present invention relates to a humanized, non-human mammal model, preferably a humanized mouse model, with an engrafted portion of human skin having hyper-patient sensitivity to ultra violet (UV) light, and a method for preparing such non-human mammal model and its use for studying acute and long term effects on human skin by exposure to UV light and for testing topically or systematically applied or administered substances for their capability to prevent, repair and/or cure damages of such exposed human skin. This mouse model comprises an engrafted portion of human skin based on skin cells of a human Xeroderma pigmentosum (XP) or Gorlin's Syndrome (GS) patient. XP and GS are rare human autosomal disorders characterized clinically by hypersensitivity to UV light, especially to UVB rays, and high predisposition for developing skin cancers on sunlight exposed skin areas. | 03-12-2009 |
Marta Garcia Gomar, Mostoles (madrid) ES
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20110071831 | Method and System for Localizing and Authenticating a Person - The present invention refers to a method for localizing a person comprising the steps carried out in a computing system ( | 03-24-2011 |
Marta Garcia Gomar, Madrid ES
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20110026690 | METHOD OF INFORMING A PERSON OF AN EVENT AND METHOD OF RECEIVING INFORMATION ABOUT AN EVENT, A RELATED COMPUTING - The invention refers to a Method of informing a person of an event comprising carrying out in a computing system the steps of: receiving ( | 02-03-2011 |
20110246198 | METHOD FOR VERYFYING THE IDENTITY OF A SPEAKER AND RELATED COMPUTER READABLE MEDIUM AND COMPUTER - The present invention refers to a method for verifying the identity of a speaker based on the speakers voice comprising the steps of: a) receiving a voice utterance; b) using biometric voice data to verify ( | 10-06-2011 |
20120173239 | METHOD FOR VERIFYING THE IDENTITYOF A SPEAKER, SYSTEM THEREFORE AND COMPUTER READABLE MEDIUM - The invention refers to a method of verifying the identity of a speaker based on the speakers voice comprising the steps of: receiving ( | 07-05-2012 |
20130225128 | SYSTEM AND METHOD FOR SPEAKER RECOGNITION ON MOBILE DEVICES - A speaker recognition system for authenticating a mobile device user includes an enrollment and learning software module, a voice biometric authentication software module, and a secure software application. Upon request by a user of the mobile device, the enrollment and learning software module displays text prompts to the user, receives speech utterances from the user, and produces a voice biometric print. The enrollment and training software module determines when a voice biometric print has met at least a quality threshold before storing it on the mobile device. The secure software application prompts a user requiring authentication to repeat an utterance based at least on an attribute of a selected voice biometric print, receives a corresponding utterance, requests the voice biometric authentication software module to verify the identity of the second user using the utterance, and, if the user is authenticated, imports the voice biometric print. | 08-29-2013 |
20140081638 | CUT AND PASTE SPOOFING DETECTION USING DYNAMIC TIME WARPING - The invention refers to a method for comparing voice utterances, the method comprising the steps: extracting a plurality of features ( | 03-20-2014 |
20140379332 | IDENTIFICATION OF A LOCAL SPEAKER - Method for speaker identification includes detecting a target speaker's utterance locally; extracting features from the detected utterance locally, analyzing the extracted features in the local device to obtain information on the speaker identification and/or encoding the extracted features locally, transmitting the encoded extracted features to a remote server, decoding and analyzing the received extracted features by the server to obtain information on the speaker identification, and transmitting the information on the speaker identification from the server to the location where the speaker's utterance was detected. The method further includes detecting speech activity locally. Extracting features, encoding the extracted features, and/or transmitting the encoded extracted features to the server, are only performed if speech activity above some predetermined threshold is detected. | 12-25-2014 |
Marta Gibert Gutierrez, Bellaterra ES
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20100144536 | NANOSTRUCTURED SUPERCONDUCTING MATERIAL OF TYPE REBa2Cu3O7 (RE = RARE EARTH OR YTTRIUM) WITH A HIGH DENSITY OF VORTEX ANCHORING CENTRES AND PREPARATION METHOD THEREOF - The present invention relates to a nanostructured superconducting material of type REBa | 06-10-2010 |
Marta Gomez-Burgaz, Madrid ES
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20090232858 | METHOD AND PROCESS FOR THE PRODUCTION OF MULTI-COATED RECOGNITIVE AND RELEASING SYSTEMS - The present invention includes compositions, methods, systems for the controlled delivery of an active agent in a tablet polymer comprising two or more layers, wherein each of the two or more layers comprises at least one active agent and at least one molecular recognition polymer, wherein the two or more layers are compressed into a single tablet. | 09-17-2009 |
Marta Gomez Garcia, Sevilla ES
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20100086648 | CARAMELS WITH HIGH CONTENT IN PREBIOTIC OLIGOSACCHARIDES, PROCEDURE OF PREPARATION AND USE - The present invention relates to the transformation of food-grade sugars containing D-fructose, in caramels enriched in oligosaccharides with prebiotic activity by using solid acid catalysts, such as zeolites, clays or ion-exchange resins in its acid form, under heterogeneous conditions, or by using soluble acid polymer catalysts of high molecular weight, under homogeneous conditions, with the possibility of recycling the catalyst, being compatible with discontinuous or continuous production processes. The resulting caramel exhibits prebiotic properties, favoring the development of a beneficial intestinal flora and a repairing effect in the damaged colon. | 04-08-2010 |
Marta Gomez Garcia, Seville ES
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20100093662 | NOVEL AMPHIPHILIC CYCLODEXTRIN DERIVATIVES - The present invention relates to cyclodextrins having the following formula (I): to nanostructures comprising them, to processes for preparing them, to the use thereof, and also to compositions comprising them. | 04-15-2010 |
Marta Gorraiz Ayala, Navarra ES
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20090220532 | Agents and methods based on the use of the eda domian of fibronectin - This invention relates to the use of a polypeptide in the production of an immunostimulatory agent, said polypeptide comprising a sequence corresponding to the EDA domain of fibronectin, a fragment of the EDA domain which can bind to TLR4 or a variant of said EDA domain or a fragment which can bind to TLR4 and which has a homology of more than 70% with any form or natural fragment of the EDA domain. The invention also relates to the production methods and applications of said agent. | 09-03-2009 |
Marta Huguet Riba, Barcelona ES
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20090155369 | PHARMACEUTICAL COMPOSITION CONTAINING LEVODOPA, ENTACAPONE AND CARBIDOPA - The present invention refers to a solid pharmaceutical composition of entacapone, levodopa and carbidopa or pharmaceutically acceptable salts thereof characterized in that entacapone is in the form of granules and it is added separately to levodopa and carbidopa. In addition, this invention provides the process for its preparation. | 06-18-2009 |
Marta Izquierdo Rojo, Cantoblanco ( Madrid) ES
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20100028366 | SYNERGISTIC EFFECT BETWEEN A CYANOGENIC SYSTEM AND ANOTHER OXIDATIVE INDUCING SYSTEM FOR TREATING TUMORS - The invention relates to a system capable of causing the death of tumor cells by activating caspase-independent apoptosis, comprising: | 02-04-2010 |
Marta Karczewcz, San Diego, CA US
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20100316122 | MULTIVIEW VIDEO CODING OVER MPEG-2 SYSTEMS - A multiplexer may produce an MPEG-2 (Motion Picture Experts Group) System standard bitstream comprising views with nonconsecutive view order indexes. In one example, an apparatus comprises a video encoder that encodes a plurality of views of a scene, a multiplexer that constructs a data structure for signaling that a corresponding MPEG-2 (Motion Picture Experts Group) System standard bitstream comprises a first view of the plurality of views of the scene associated with a first view order index and a second view of the plurality of views of the scene associated with a second view order index, wherein the first view order index and the second view order index are non-consecutive, and an output interface that outputs the data structure. | 12-16-2010 |
Marta Krzyzak, Alfeld DE
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20110111203 | SUBSTRATE WITH A SOL-GEL LAYER AND METHOD FOR PRODUCING A COMPOSITE MATERIAL - A substrate with a sol-gel layer and to a method for producing a composite material wherein a barrier layer is placed between the sol-gel layer and the substrate are provided. | 05-12-2011 |
20140147654 | SUBSTRATE ELEMENT FOR COATING WITH AN EASY-TO-CLEAN COATING - A substrate element for coating with an easy-to-clean coating, the effect of the easy-to-clean coating being improved by the substrate element in terms of its hydrophobic and oleophobic properties and also, more particularly, its long-term stability. The substrate element comprises in particular a support material of glass or glass-ceramic and an antireflection coating, consisting of one layer or of at least two layers, the one layer or the topmost layer of the at least two layers being an adhesion promoter layer which is able to interact with an easy-to-clean coating and comprises a mixed oxide, more particularly a silicon mixed oxide. | 05-29-2014 |
Marta Labeur, Munchen DE
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20100069463 | METHODS FOR THE DIAGNOSIS AND TREATMENT OF AFFECTIVE DISORDERS AND CUSHING'S SYNDROMES - The present invention relates to a method for identifying a TMEFF2 modulator, comprising (a) contacting a cell which expresses TMEFF2 with a candidate compound to be tested; (b) measuring whether said compound to be tested decreases or increases the level of a constituent of the cAMP signalling pathway, preferably the CRH signalling pathway, in said cell when compared to a corresponding cell which does not express TMEFF2; (b′) optionally determining whether said compound is capable of reduncing the binding between Activin and TMEFF2; and (c) identifying said modulator compound. Furthermore, a method for identifying a TMEFF2 modulator comprising determining whether said TMEFF2 modulator is capable of reducing the binding between Activin and TMEFF2 is contemplated. It also relates to uses and methods applying a TMEFF2 agonist for the treatment of Cushing's Syndromes and a TMEFF2 modulator for the treatment of affective disorders. Furthermore, methods of diagnosing affective disorders or Cushing's Syndromes are provided. | 03-18-2010 |
Marta Lacaba, Tudela ES
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20080282818 | Sensors with nanoparticles - A sensor is provided with a base with at least one resistive track which includes a nano particle based conductive ink. A contact device makes contact along at least a portion of the resistive track and provides an indication of position or movement. | 11-20-2008 |
Marta Laszcz, Warszawa PL
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20110065922 | Process for Preparation Of Solifenacin and/or the Pharmaceutically Acceptable Salts Thereof of High Pharmaceutical Purity - A process for the preparation of solifenacin and/or the pharmaceutically acceptable salts thereof of high pharmaceutical purity is characterized in that 3-(R)-quinuclidinoloxy anion generated in situ from 3-(R)-quinuclidinol in a presence of strong base in polar organic solvent is subject to acylation with (S)-1-phenyl-1,2,3,4-tetrahydroisoquinolinecarbonyl chloride of chemical purity at least 98%, while maintaining constant anion excess in a reaction mixture, and after reaction completion solifenacin base is optionally transformed into solifenacin salt according to standard procedures. (S)-1-Phenyl-1,2,3,4-tetrahydroisoquinolinecarbonyl chloride of chemical purity at least 98% is obtained in a reaction of (S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline and molar excess of phosgene in a presence of tertiary aromatic amine in aromatic hydrocarbon, and isolated in a crystalline form. | 03-17-2011 |
20110077405 | PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE (S)-1-PHENYI-1,2,3,4- TETRAHYDROISOQUINOLINE - Process for preparation of (S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline wherein 1-phenyl-1,2,3,4-tetrahydroisoquinoline is reacted with D-(−)-tartaric acid in a solvent system comprising of methanol and water, preferably at 3.3:1 to 1:1 volume ratio, the crystallization mixture is left for crystallization and (S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline is released from obtained crystalline diastereoisomeric salt according to standard procedures. (S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is the intermediate in enantiomeric synthesis of solifenacin. | 03-31-2011 |
20130190538 | PROCESS FOR THE PREPARATION OF PROTOESCIGENIN - A process for the preparation of protoescigenin by hydrolysis of escin isolated from | 07-25-2013 |
Marta Lomnytska, Lviv UA
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20080213907 | Protein markers for the diagnosis and prognosis of ovarian and breast cancer - Plasma samples of ovarian and breast cancer patients were used to search for markers of cancer, using two-dimensional gel electrophoresis and MALDI TOF mass spectrometry. Truncated forms of cytosolic serine hydroxymethyl transferase (cSHMT), T-box transcription factor 3 (Tbx3) and utrophin were aberrantly expressed in samples from cancer patients, as compared to samples from noncancer cases. Aberrant expression of proteins was validated by immunoblotting of plasma samples with specific antibodies to cSHMT, Tbx3 and utrophin. A cohort of 79 breast and 39 ovarian cancer patients, and 31 individuals who were either healthy or had noncancerous conditions was studied. We observed increased expression of truncated cSHMT, Tbx3 and utrophin in plasma samples obtained from patients at early stages of disease. The results indicate that cSHMT, Tbx3, utrophin and truncated forms thereof can be used as components of multiparameter monitoring of ovarian and breast cancer. | 09-04-2008 |
20120238478 | PROTEIN MARKERS FOR THE DIAGNOSIS AND PROGNOSIS OF OVARIAN AND BREAST CANCER - Plasma samples of ovarian and breast cancer patients were used to search for markers of cancer, using two-dimensional gel electrophoresis and MALDI TOF mass spectrometry. Truncated forms of cytosolic serine hydroxymethyl transferase (cSHMT), T-box transcription factor 3 (Tbx3) and utrophin were aberrantly expressed in samples from cancer patients, as compared to samples from noncancer cases. Aberrant expression of proteins was validated by immunoblotting of plasma samples with specific antibodies to cSHMT, Tbx3 and utrophin. A cohort of 79 breast and 39 ovarian cancer patients, and 31 individuals who were either healthy or had noncancerous conditions was studied. We observed increased expression of truncated cSHMT, Tbx3 and utrophin in plasma samples obtained from patients at early stages of disease. The results indicate that cSHMT, Tbx3, utrophin and truncated forms thereof can be used as components of multiparameter monitoring of ovarian and breast cancer. | 09-20-2012 |
Marta Marfil Sánchez, Barcelona ES
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20090137841 | PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE - Process for the obtaining of 1-adamantane (tricycle[3.3.1.1 (3,7)]decane) derivatives, or of a pharmaceutically acceptable salt thereof, based on a carboxylation reaction, via metallation, of a precursor compound with an adequate leaving group. It also comprises the preparation of the precursor compound by means of a selective coupling of the corresponding boron, magnesium or zinc derivative with the corresponding disubstitute aromatic derivative. It is especially useful for the obtaining of Adapalene at industrial scale with good yield and high purity. | 05-28-2009 |
20100010265 | PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE - Process for the obtaining of 1-adamantane (tricycle[3.3.1.1 (3,7)]decane) derivatives, or of a pharmaceutically acceptable salt thereof, based on a carboxylation reaction, via metallation, of a precursor compound with an adequate leaving group. It also comprises the preparation of the precursor compound by means of a selective coupling of the corresponding boron, magnesium or zinc derivative with the corresponding disubstitute aromatic derivative. It is especially useful for the obtaining of Adapalene at industrial scale with good yield and high purity. | 01-14-2010 |
20110040115 | INTERMEDIATES AND PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE - Process for the preparation of aromatic derivatives of 1-adamantane (tricyclo[3.3.1.1 (3,7)]decane), or an acceptable pharmaceutical salt thereof, based on a hydrolysis reaction of a precursor cyano compound. It also comprises different processes for obtaining the cyano compound. It is especially useful for obtaining Adapalene on an industrial scale in high yield and purity. It also comprises new intermediates useful in said preparation process. | 02-17-2011 |
Marta Marfil Sánchez, Barcelona ES
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20110040115 | INTERMEDIATES AND PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE - Process for the preparation of aromatic derivatives of 1-adamantane (tricyclo[3.3.1.1 (3,7)]decane), or an acceptable pharmaceutical salt thereof, based on a hydrolysis reaction of a precursor cyano compound. It also comprises different processes for obtaining the cyano compound. It is especially useful for obtaining Adapalene on an industrial scale in high yield and purity. It also comprises new intermediates useful in said preparation process. | 02-17-2011 |
Marta Martin-Portugues, Ludwigshafen DE
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20080207866 | Radiation-Curable Binder - The present invention relates to a radiation-curable binder obtainable by reacting A) amine-formaldehyde condensates with a molar ratio of formaldehyde to amino groups of 1:6 to 2:1 with B) a mixture of butanediol monoacrylate and 2-hydroxethyl methacrylate in a ratio of 0.1:100 to 100:0.1, using 0.1 to 1.5 hydroxy equivalents of component B) per methylol equivalent of component A). The present invention further relates to a curable coating composition which comprises the binder of the invention and to a coated article produced using the coating composition. | 08-28-2008 |
20100048813 | HIGHLY-BRANCHED OR HYPER-BRANCHED POLYESTER AND THE PRODUCTION AND APPLICATION THEREOF - The present invention relates to highly branched or hyperbranched polyesters of specific construction, based on mono-, di-, tri- or polycarboxylic acids or derivatives thereof and mono-, di-, tri-, tetra- or polyols, to processes for preparing them, and to their use. | 02-25-2010 |
20100273932 | POLYISOCYANATE CONTAINING URETHANE GROUPS - The present invention relates to new, urethane-group-containing polyisocyanates based on isophorone diisocyanate and to their use. | 10-28-2010 |
20100273938 | POLYISOCYANATES CONTAINING ALLOPHANATE GROUPS - The present invention relates to new, allophanate-group-containing polyisocyanates based on isophorone diisocyanate and to their use. | 10-28-2010 |
20110257329 | QUICK-DRYING COATING COMPOUNDS - The present invention relates to quick-drying two-component polyurethane coating compositions, to processes for preparing them, and to their use. | 10-20-2011 |
20120108784 | HIGHLY-BRANCHED OR HYPER-BRANCHED POLYESTER AND THE PRODUCTION AND APPLICATION THEREOF - A nongelling and noncrosslinked, highly branched or hyperbranched polyester, obtained by reacting at least one selected from the group consisting of a monocarboxylic acid, a dicarboxylic acid, a tricarboxylic acid, a polycarboxylic acid, and a derivative thereof with at least one selected from the group consisting of a monoalcohol, a diol, a triol, a tetraol, and a polyol, wherein an average functionality of the carboxyl groups (f.A) and the hydroxyl groups (f.B) in a notionally hydrolyzed polyester satisfies a relation: f.A+f.B>4, a mole fraction of the carboxyl groups (x.A) in the notionally hydrolyzed polyester satisfies a relation: f.A/[(f.A*f.B)+f.A]≦x≦(f.A*f.B)/[(f.A*f.B)+f.B], and a degree of conversion (U) of the deficit functionality satisfies a relation: U.min≦U≦U.max. | 05-03-2012 |
Marta Mas Torrent, Bellatera ES
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20100028209 | ORGANIC SENSOR DEVICE AND ITS APPLICATIONS - The invention is characterised in that it has a layer of organic material sensitive to changes in pressure, voltage, deformation, gases and/or temperature; wherein said organic layer consists of at least one conductive salt or complex including a molecule A and a dopant D, said molecule A being an electron donor or acceptor organic molecule or macromolecule capable of forming a conductive salt or complex, which without doping is not conductive, and with the presence of dopant D becomes a compound that is donor or acceptor of electrons and capable of forming conductive salt or complex with the molecule or macromolecule A; and a base substrate, in close contact with said layer of organic material. The sensor device is useful in molecular electronics or plastic electronics, in particular, in the field of organic sensors. | 02-04-2010 |
Marta Mas Torrent, Bellaterra ES
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20090302279 | Method of Obtaining Patterns In an Organic Conductor Substrate and Organic Material Thus Obtained - The invention relates to a chemical method that enables the direct design of a pattern on an organic substrate having semiconductor-, superconductor- or metallic-type conducting properties. The invention also relates to the organic material thus obtained, which is intended for use in electronic devices, such as resistors, capacitors, transistors, sensors or electrodes among others, or for use in other applications requiring a determined pattern of conductor or semiconductor zones and less-conducting, non-conducting or insulating zones. | 12-10-2009 |
Marta Mas-Torrent, Barcelona ES
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20110184271 | SENSOR CONTACT LENS, SYSTEM FOR THE NON-INVASIVE MONITORING OF INTRAOCULAR PRESSURE AND METHOD FOR MEASURING SAME - The invention is characterized in that it comprises a truncated contact lens ( | 07-28-2011 |
Marta Miguel Castro, Madrid ES
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20100048464 | Bioactive peptides identified in enzymatic hydrolyzates of milk caseins and method of obtaining same - The invention relates to the production of bioactive products that are derived from milk proteins for the production of bioactive milk products derived from milk proteins, particularly caseins. The 16 inventive peptides can be obtained chemically, biotechnologically or by means of enzymatic treatment from proteins containing same and give rise to peptides with an antimicrobial activity, an in vitro angiotensin converter inhibitor activity and/or antihypertensive activity and/or antioxidant activity. Said nutraceutical products are suitable for use in the food and pharmaceutical industries, both in the form of a hydrolyzate or bioactive peptides. | 02-25-2010 |
Marta Monjo, Palma De Mallorca ES
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20110166670 | PUFA COVERED IMPLANTS - A medical or dental implant which contains a metal material selected from the group consisting of titanium or an alloy thereof, wherein at least part of the surface of the metal material is coated with a layer of a polyunsaturated fatty acids (PUFA). In a preferred embodiment, the implant has been exposed to UV radiation for at least 30 seconds before, simultaneously with and/or after the coating with PUFA. Depending on the concentration of polyunsaturated fatty acids on the surface, at least parts of the implant exhibits improved effect on adhesion of mineralized and/or hard tissue, such as on bone remodeling and/or improved biocompatibility, or alternatively inhibits adhesion of mineralized and/or hard tissue to the implant. The metal material is preferably titanium, the polyunsaturated fatty acid is preferably EPA. | 07-07-2011 |
20130017234 | IMPLANT MODIFIED WITH NON-HYDROXYLATED VITAMIN D PRECURSORS - An implant to be used as medical or dental implant, comprising a metallic or polymeric base which is covered by the vitamin D precursor cholecalciferol. The implant can be obtained by direct covering of the polymeric or metallic base with a solution comprising cholecalciferol or also covering the base with the 7-dehydrocholesterol (7-DHC), and subsequently irradiated with UV light to induce the formation of cholecalciferol. Optionally, the coating of the implant may include an antioxidant such as vitamin E. This implant enhances osseointegration in compromised patients by means of the endogenous synthesis and activity of vitamin D in hard and mineralized tissue regeneration. Furthermore, a method to obtain these implants which comprises coating the surface of the implant directly with cholecalciferol or with a specific concentration of 7-DHC and irradiated with UV light to induce the formation of cholecalciferol. | 01-17-2013 |
Marta Mottura, Milano (mi) IT
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20090152733 | DEEP CONTACTS OF INTEGRATED ELECTRONIC DEVICES BASED ON REGIONS IMPLANTED THROUGH TRENCHES - An embodiment of an integrated circuit includes first and second semiconductor layers and a contact region disposed in the second layer. The first semiconductor layer is of a first conductivity, and the second semiconductor layer is disposed over the first layer and has a surface. The contact region is contiguous with the surface, contacts the first layer, includes a first inner conductive portion, and includes an outer conductive portion of the first conductivity. The contact region may extend deeper than conventional contact regions, because where the inner conductive portion is formed from a trench, doping the outer conductive portion via the trench may allow one to implant the dopants more deeply than conventional techniques allow. | 06-18-2009 |
20130017676 | DEEP CONTACTS OF INTEGRATED ELECTRONIC DEVICES BASED ON REGIONS IMPLANTED THROUGH TRENCHES - An embodiment of an integrated circuit includes first and second semiconductor layers and a contact region disposed in the second layer. The first semiconductor layer is of a first conductivity, and the second semiconductor layer is disposed over the first layer and has a surface. The contact region is contiguous with the surface, contacts the first layer, includes a first inner conductive portion, and includes an outer conductive portion of the first conductivity. The contact region may extend deeper than conventional contact regions, because where the inner conductive portion is formed from a trench, doping the outer conductive portion via the trench may allow one to implant the dopants more deeply than conventional techniques allow. | 01-17-2013 |
Marta Mottura, Phoenix, AZ US
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20100075484 | SOI DEVICE WITH CONTACT TRENCHES FORMED DURING EPITAXIAL GROWING - A method for manufacturing an integrated electronic device. The method includes providing an SOI substrate having a semiconductor substrate, an insulating layer on the semiconductor substrate, and a semiconductor starting layer on the insulating layer; epitaxially growing the starting layer to obtain a semiconductor active layer on the insulating layer for integrating components of the device, and forming at least one contact trench extending from an exposed surface of the starting layer to the semiconductor substrate before the step of epitaxially growing the starting layer, wherein each contact trench clears a corresponding portion of the starting layer, of the insulating layer and of the semiconductor substrate, the epitaxial growing being further applied to the cleared portions thereby at least partially filling the at least one contact trench with semiconductor material. | 03-25-2010 |
Marta Obadalova, Brno CZ
Marta Perez Alvarez, Madrid ES
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20080269511 | Total Synthesis of Myriaporones - Compounds of the general formula (I) or a pharmaceutically acceptable salt, derivative, prodrug or stereoisomer thereof are provided: wherein the substituent groups defined by R are each independently selected from the group consisting of H, SiR′ | 10-30-2008 |
Marta Planas Grabuleda, Girona ES
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20100016167 | ANTIMICROBIAL LINEAR PEPTIDES - The present invention relates to novel linear peptides with antimicrobial activity. Said peptides are made up of 11 amino acids, and they have the amino group of the amino acid constituting the N-terminal end in a non-derived form or functionalized with an acetyl group, p-toluene sulphonyl, benzyl or benzoyl. The amino acid constituting the C-terminal end of said peptides is in carboxamide form. The invention describes the synthesis and use of said peptides as antimicrobial agents to combat pathogenic bacteria for plants. The invention also relates to compositions containing said peptides and an auxiliary agent, and to a method for preventing and treating infections and diseases of plants caused by pathogenic bacteria. | 01-21-2010 |
Marta Pomares Marco, Sant Cugat Del Valles ES
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20110152543 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE (S)-(-)-2-(N-PROPYLAMINO)-5-METHOXYTETRALINE AND (S)-(-)-2-(N-PROPYLAMINO)-5-HYDROXYTETRALINE COMPOUNDS - The present invention describes a novel process for the preparation of optically active (S)-(−)-2-(N-propylamino)-5-methoxytetraline and (S)-(−)-2-(N-propylamino)-5-hydroxytetraline compounds based on the optical resolution of mixtures of the enantiomers of 2-(N-propylamino)-5-methoxytetraline and 2-(N-propylamino)-5-hydroxytetraline respectively. This process comprises (a) reacting a mixture of the enantiomers of said compounds with an optically active organic acid to form diastereoisomeric salts and separating the salts by crystallization. Said compounds are useful in the preparation of (6S)-(−)-5,6,7,8-tetrahydro-6-[propyl-(2-thienyl)ethyl]amino-1-naphthol (Rotigotine). Rotigotine is a dopamine agonist and is indicated for the treatment of Parkinson's disease. | 06-23-2011 |
Marta Pomares Marco, Sta Perpetua De Mogoda ES
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20090005429 | PROCESS FOR THE PREPARATION OF CARVEDILOL AND ITS ENANTIOMERS - The present invention relates to a process for the preparation of carvedilol as well as of the optically active R and S enantiomers thereof and of mixtures of these enantiomers and, more particularly, relates to an improved process for the preparation of carvedilol and its enantiomers characterized by the use of ethyl acetate as reaction solvent. | 01-01-2009 |
20120041044 | PROCESS FOR THE PREPARATION OF CARVEDILOL AND ITS ENANTIOMERS - The present invention relates to a process for the preparation of carvedilol as well as of the optically active R and S enantiomers thereof and of mixtures of these enantiomers and, more particularly, relates to an improved process for the preparation of carvedilol and its enantiomers characterized by the use of ethyl acetate as reaction solvent. | 02-16-2012 |
Marta Princep, Barcelona ES
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20080221073 | Nitrooxy Derivatives of Glucocorticoids - The invention relates to new steroids nitrooxyderivatives, to topical pharmaceutical formulations thereof, and their use for treating skin or mucosal membrane diseases or disorders. These new steroids nitrooxyderivatives have an improved pharmacological activity and enhanced local tolerability. | 09-11-2008 |
20090258849 | NITROOXY DERIVATIVES OF GLUCOCORTICOIDS - The invention relates to new steroids nitrooxyderivatives, to topical pharmaceutical formulations thereof, and their use for treating skin or mucosal membrane diseases or disorders. These new steroids nitrooxyderivatives have an improved pharmacological activity and enhanced local tolerability. | 10-15-2009 |
20090264393 | NITROOXY DERIVATIVES OF GLUCOCORTICOIDS - The invention relates to new steroids nitrooxyderivatives, to topical pharmaceutical formulations thereof, and their use for treating skin or mucosal membrane diseases or disorders. These new steroids nitrooxyderivatives have an improved pharmacological activity and enhanced local tolerability. | 10-22-2009 |
20090264394 | NITROOXY DERIVATIVES OF GLUCOCORTICOIDS - The invention relates to new steroids nitrooxyderivatives, to topical pharmaceutical formulations thereof, and their use for treating skin or mucosal membrane diseases or disorders. These new steroids nitrooxyderivatives have an improved pharmacological activity and enhanced local tolerability. | 10-22-2009 |
20110294769 | NITROOXY DERIVATIVES OF GLUCOCORTICOIDS - The invention relates to new steroids nitrooxyderivatives, to topical pharmaceutical formulations thereof, and their use for treating skin or mucosal membrane diseases or disorders. These new steroids nitrooxyderivatives have an improved pharmacological activity and enhanced local tolerability. | 12-01-2011 |
Marta Reinoso Garcia, Mannheim DE
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20110098363 | AMPHIPHILIC MOLECULES WITH A TRIAZINE CORE - The present invention is directed to chemical compounds of formula (I) wherein A1 is selected from the group consisting of alkyl, aryl, alkylaryl and (formula A), A2, A3, A4, A5 and in case A1 is (formula A) also A6 and A7 comprise a polymer selected from the group consisting of [EO] | 04-28-2011 |
Marta Rey-Babarro, Seattle, WA US
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20100318889 | Automatic Insertion of Data from Web Forms into Documents - A host computing system automatically inserts data submitted from web forms into documents. The host computing system stores a document file comprising data that represents a document. The document comprises at least one document element. The host computing system receives a block of web form data. The block of web form data comprises a value assigned to a web form element in a web form. In response to receiving the block of web form data, the host computing system automatically updates the document element to specify the value when the document file comprises element mapping metadata that maps the document element to the web form element. | 12-16-2010 |
20100318890 | Architecture to Expose Internal Business Data on a Website - A method for importing document data into a website hosted on a server computer includes a block of document data that is received at the server computer. The block of document data includes data from an identified section of a document. In response to receiving the block of document data, the server computer automatically updates a web page component on the website. The web page component is selected via a document widget on the server computer. The document data is mapped to the web page component. | 12-16-2010 |
20100318894 | Modifications to Editable Elements of Web Pages Rendered in Word Processor Applications - A word processor application presents a word processor user interface containing a word processor document. The word processor application generates the word processor document by rendering a web page file. The word processor document includes editable elements and non-editable elements. The web page file indicates which elements of the web page file are rendered as editable elements and which elements of the web pages are rendered as non-editable elements. In some instances, the non-editable elements are common to each web page in a web site. The user edits the content of the editable elements. When the user saves the word processor document, the client computing system sends a page modification request to a server computing system. In response, the server computing system modifies the web page file such that corresponding editable elements of the web page file specify the content of the editable elements in the word processor document. | 12-16-2010 |
20120035925 | Population of Lists and Tasks from Captured Voice and Audio Content - Automatic capture and population of task and list items in an electronic task or list surface via voice or audio input through an audio recording-capable mobile computing device is provided. A voice or audio task or list item may be captured for entry into a task application interface or into a list authoring surface interface for subsequent use as task items, reminders, “to do” items, list items, agenda items, work organization outlines, and the like. Captured voice or audio content may be transcribed locally or remotely, and transcribed content may be populated into a task or list authoring surface user interface that may be displayed on the capturing device (e.g., mobile telephone), or that may be stored remotely and subsequently displayed in association with a number of applications on a number of different computing devices. | 02-09-2012 |
20130019153 | Architecture to Expose Internal Business Data on a Website - A method for importing document data into a website hosted on a server computer includes a block of document data that is received at the server computer. The block of document data includes data from an identified section of a document. In response to receiving the block of document data, the server computer automatically updates a web page component on the website. The web page component is selected via a document widget on the server computer. The document data is mapped to the web page component. | 01-17-2013 |
20130091453 | Motivation of Task Completion and Personalization of Tasks and Lists - Personalized task management is provided. A “doodling” zone or pane is provided in association with an electronic task interface that allows for entry of sketches, notes, the playing of games, and the like in association with entry, editing and use of task or list items in the task interface. In addition, task items entered into the task interface may be associated with other information, including previously entered or accomplished tasks, third party task content, enterprise task content, or other content. As tasks are completed, a completing user may be rewarded with a variety of on-display animations, gifts, reward items and/or other positive feedback. | 04-11-2013 |
Marta Rodriguez Franco, Freiburg ES
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20080201804 | Protein Production - The present invention relates to a method for producing heterologous glycosylated proteins in non-animal eukaryotic cells such as in transformed bryophyte, yeast, ciliate or algae cells. In particular, the method relates to a method for producing glycosylated proteins comprising animal glycosylation patterns—comprising sialic acid residues—, such as pharmaceutical proteins for use in mammals, e.g. humans, in bryophyte cells such as those of | 08-21-2008 |
Marta Rodriguez-Franco, Freiburg DE
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20090111187 | Moss Expressing Promotion Regions - Disclosed are isolated nucleic acid molecules encoding wild type nucleus derived moss expression promoting regions (MEPRs) as well as a method for producing recombinant polypeptides using such MEPRs. | 04-30-2009 |
Marta Ruiz Egozcue, Navarra ES
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20090220533 | Novel T-Helper Antigenic Determinant (THD) Peptides - The invention relates to a chimeric peptide, which can bind to at least one allelic form of the HLA-DR molecule. The invention also relates to a pharmaceutical composition containing said peptide, as well as to the different uses of same. | 09-03-2009 |
Marta Ruiz Guillén, Pamplona-Navarra ES
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20100055736 | VIRAL VECTOR AND USES THEREOF - The invention relates to a viral vector comprising a mutated replicon of the Semliki Forest virus (SFV) in the nucleotide sequence encoding subunit nsp2 of the SFV replicase. Said viral vector can be used to generate stable cell lines which can constitutively express heterologous products of interest. | 03-04-2010 |
Marta Ruiz Guillén, Pamplona-Navarra ES
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20100055736 | VIRAL VECTOR AND USES THEREOF - The invention relates to a viral vector comprising a mutated replicon of the Semliki Forest virus (SFV) in the nucleotide sequence encoding subunit nsp2 of the SFV replicase. Said viral vector can be used to generate stable cell lines which can constitutively express heterologous products of interest. | 03-04-2010 |
Marta Sainz-Vila, Berlin DE
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20100059384 | Electrodeposition method with analysis of the electrolytic bath by solid Phase Extraction - A method for electrodepositing a metal layer from an electrolytic bath is described, wherein the concentrations of at least two components of the electrolytic bath are monitored by carrying out the following steps: (a) a sample is taken from the electrolytic bath; (b) the sample is supplied to a column for solid phase extraction, which contains a solid sorbent material; (c) the column is subjected to a washing procedure with a first eluent, wherein the at least two components remain on the column, and undesired components are eluted from the column; (d) the at least two components are eluted from the column by a second eluent; (e) the concentrations of the at least two components in the eluate obtained in step (d) are determined without separating the components from each other. In this method the use of poly(divinyl benzene-co-N-vinyl pyrrolidone) for solid phase extraction is particularly advantageous. | 03-11-2010 |
Marta Sanchez Asenjo, Mardrid ES
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20110071831 | Method and System for Localizing and Authenticating a Person - The present invention refers to a method for localizing a person comprising the steps carried out in a computing system ( | 03-24-2011 |
Marta San Martin Arribas, Madrid ES
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20110178985 | MASTER MONITORING MECHANISM FOR A GEOGRAPHICAL DISTRIBUTED DATABASE - The present invention faces the issue of data replication in different database nodes of a geographically distributed database wherein clients cannot always perform any database-related operation in the closest database node. Thus, the present invention provides for an enhanced distributed database system with a plurality of nodes, each node arranged for storing a replica of at least one partition of data, and a method of handling said distributed database system comprising the steps of: partitioning data to a number of partitions; replicating each partition into a number of replicas; for each partition, distributing the number of replicas amongst database nodes; activating more than one node; monitoring at each active node events of: latest updating of each replica, replica status, status of local resources in charge of each replica, and connectivity status of each replica; upon activation o deactivation of a node, determining which node is considered current master node for each partition in charge of current mast replica; for any request received in a node to read/write data, determining the current master node in charge of the current master replica, and routing said request to said current master node. | 07-21-2011 |
20110188506 | Distributed Master Election - A transmitting node in a telecommunications network, wherein data are distributed into one or more data storage groups (DSG), and wherein data related to a DSG is replicated into a plurality of data storage elements (DS) distributed along one or more nodes of the network. The transmitting node includes a network interface through which a bi-directional connection is established with a plurality of other nodes in a transport layer of the network, and from which messages are sent to the plurality of other nodes comprising an operational state matrix (OSM), which includes information held by the transmitting node about the operational state of the replicas of the DSs of each DSG. The transmitting node includes a memory for storing data. The transmitting node includes a processing unit which forms a list of the plurality of other nodes as having an answer pending of the node in the memory. The network interface receives an OSM from at least some of other nodes which are interpreted by the processing unit as answer messages from the list of the plurality of other nodes to the messages sent by the network interface, and which indicates that an OSM information exchange with the plurality of the other nodes is complete. The processing unit decides a node hosting the master DS replica of each DSG based on the OSM information exchange. The processing unit detects changes in a view of the world (VOW) which includes an accumulated set of OSMs with respect to each DSG hosted by the transmitting node. The network interface sends messages comprising changes in the VOW to the other nodes. | 08-04-2011 |
Marta Santure, Chicoutimi CA
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20100087462 | METHODS FOR PREDICTING AND DETECTING INTOLERANCE TO AN HYPOLIPIDEMIC AGENT - The invention describes methods and tools for the identification of drug intolerance into subjects receiving an hypolipidemic agent. The invention further describes methods and tools for the prediction of drug intolerance in subjects in need of hypolipidemic agents. Some aspects of the invention are based on the assessment of the subject plasma glycerol concentrations. Some aspects of the invention are based on the assessment of the subject HDL-triglycerides concentration. Some other aspects are based on the identification of hepatic lipase gene variants in a subject genome. | 04-08-2010 |
Marta Scatena, Seattle, WA US
Marta Serrano Munoz, Barcelona ES
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20090298923 | Salicylate Conjugates Useful for Treating Metabolic Disorders - The present invention is directed to methods for treating metabolic disorders with compounds that are conjugates. The conjugates of the present invention are comprised of salicylic acid, triflusal, diflusinal, salsalate, IMD-0354, ibuprofen, diclofenac, licofelone, or HTB, and one or more antioxidants. | 12-03-2009 |
20100234452 | Anti-Inflammatory and Antioxidant Conjugates Useful for Treating Metabolic Disorders - The present invention is directed to methods for treating metabolic disorders with compounds that are conjugates. The conjugates of the present invention are comprised of salicylic acid, triflusal, diflusinal, salsalate, IMD-0354, ibuprofen, diclofenac, licofelone, or HTB, and one or more antioxidants. | 09-16-2010 |
20100239552 | Combination Therapies for Treating Metabolic Disorders - This invention is directed to pharmaceutical combinations comprising an antioxidant agent, an anti-inflammatory agent, and optionally at least one other anti-diabetic agent useful for treating metabolic disorders. This invention also encompasses pharmaceutically acceptable compositions comprising an antioxidant agent, an anti-inflammatory agent, optionally at least one other anti-diabetic agent, and at least one pharmaceutically acceptable carrier. The combinations and compositions of this invention are useful as methods for treating metabolic disorders including diabetes, particularly Type I and Type II diabetes, as well as diseases and disorders associated with diabetes, including but not limited to atherosclerosis, cardiovascular disease, inflammatory disorders, nephropathy, neuropathy, retinopathy, β-cell dysfunction, dyslipidemia, LADA, metabolic syndrome, hyperglycemia, insulin resistance, and/or chronic obstructive pulmonary disease in a mammal, particularly a diabetic mammal, and specifically a human patient. This invention is particularly directed to pharmaceutical compositions comprising an lipoic acid, one or more anti-inflammatories selected from the group consisting of diflunisal, diclofenac, dexibuprofen, dexketoprofen, naproxen, and salicylate, and optionally one or more pharmaceutically acceptable carriers. The compositions of this invention are useful as methods for treating metabolic disorders including type II diabetes, insulin resistance, beta-cell dysfunction, and hyperglycemia in a patient, particularly a diabetic patient. | 09-23-2010 |
20130281413 | Salicylate Conjugates Useful For Treating Metabolic Disorders - The present invention is directed to methods for treating metabolic disorders with compounds that are conjugates. The conjugates of the present invention are comprised of salicylic acid, triflusal, diflusinal, salsalate, IMD-0354, ibuprofen, diclofenac, licofelone, or HTB, and one or more antioxidants. | 10-24-2013 |
20130281520 | Anti-Inflammatory And Antioxidant Conjugates Useful For Treating Metabolic Disorders - The present invention is directed to methods for treating metabolic disorders with compounds that are conjugates. The conjugates of the present invention are comprised of salicylic acid, triflusal, diflusinal, salsalate, IMD-0354, ibuprofen, diclofenac, licofelone, or HTB, and one or more antioxidants. | 10-24-2013 |
20140357602 | Combination Therapies For Treating Metabolic Disorders - This invention is directed to pharmaceutical combinations comprising an antioxidant agent, an anti-inflammatory agent, and optionally at least one other anti-diabetic agent useful for treating metabolic disorders. This invention also encompasses pharmaceutically acceptable compositions comprising an antioxidant agent, an anti-inflammatory agent, optionally at least one other anti-diabetic agent, and at least one pharmaceutically acceptable carrier. The combinations and compositions of this invention are useful as methods for treating metabolic disorders including diabetes, particularly Type I and Type II diabetes, as well as diseases and disorders associated with diabetes, including but not limited to atherosclerosis, cardiovascular disease, inflammatory disorders, nephropathy, neuropathy, retinopathy, β-cell dysfunction, dyslipidemia, LADA, metabolic syndrome, hyperglycemia, insulin resistance, and/or chronic obstructive pulmonary disease in a mammal, particularly a diabetic mammal, and specifically a human patient. This invention is particularly directed to pharmaceutical compositions comprising an lipoic acid, one or more anti-inflammatories selected from the group consisting of diflunisal, diclofenac, dexibuprofen, dexketoprofen, naproxen, and salicylate, and optionally one or more pharmaceutically acceptable carriers. The compositions of this invention are useful as methods for treating metabolic disorders including type II diabetes, insulin resistance, beta-cell dysfunction, and hyperglycemia in a patient, particularly a diabetic patient. | 12-04-2014 |
Marta Tarruella Delsams, Lleida ES
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20100034885 | FORMULATIONS CONTAINING GLIMEPIRIDE AND/OR ITS SALTS - The invention relates, in general, to new formulations and dosage units containing glimepiride of defined particle size and/or salts thereof that are useful for the therapeutic treatment (including prophylactic treatment) of mammals, including humans, without the need for micronizing any excipients together with the glimepiride that advantageously saves time, energy and resources and a process for making the same. In particular, the invention can be useful for the treatment of diabetes. | 02-11-2010 |
Marta Tolos, Vilassar De Mar ES
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20090031882 | Method for Classifying Music - A method for classifying music includes providing music classification data, providing an unclassified piece of music to be classified, and deriving for each music class within the music classification data a respective Gish distance value. A finite set of a finite number of Gish distance values is descriptive for the relation of the unclassified piece of music to be classified with respect to a discrete and finite set of a finite number of music classes. Alternatively, for a given piece of music to be classified, music classification data of a n-tuple of at least three numbers are obtained, which are representative for the mood of the piece of music. From the n-tuple of numbers of the music classification data a pair of two dimensional coordinate values are determined, which are representative for the mood of the piece of music. | 02-05-2009 |
Marta Weinstock-Rosin, Jerusalem IL
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20100093848 | PROPARGYLATED AMINOINDANS, PROCESSES FOR PREPARATION, AND USES THEREOF - A method for treating an individual who has been identified as having Alzheimer's disease by administering orally to the individual a therapeutically effective amount of ladostigil or a pharmaceutically active salt thereof, wherein the therapeutically effective amount is 70 mg per day, 140 mg per day, or 200 mg per day. Also, a unit dosage form of ladostigil or a pharmaceutically active salt thereof in an amount of 50 mg, 70 mg, 80 mg or 100 mg. | 04-15-2010 |
20130150438 | USE OF LOW-DOSE LADOSTIGIL FOR NEUROPROTECTION - The subject invention provides a method of preventing a neurodegenerative disease in a subject or oxidative stress in the brain of a subject, comprising administering to the subject a less than cholinesterase-inhibitory amount or a less than monoamine oxidase-inhibitory amount of R(+)-6-(N-methyl,N-ethyl-carbamoyloxy)-N′-propargyl-1-aminoindan or a salt thereof effective to prevent the neurodegenerative disease or oxidative stress in the subject. | 06-13-2013 |
20140349927 | Ladostigil Therapy For Immunomodulation - Methods for treating individuals suffering from inflammation, specifically systemic inflammation including septic shock and inflammatory conditions affecting the gastrointestinal, myocardial and endocrine systems with ladostigil. | 11-27-2014 |
20150087617 | INDOLE, INDOLINE DERIVATIVES, COMPOSITIONS COMPRISING THEM AND USES THEREOF - The invention provides indole and indoline derivatives and slats thereof, compositions comprising them and uses thereof for the treatment of diseases and disorders. | 03-26-2015 |
Marta Zalewska, Montreal CA
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20110109040 | ROULETTE-TYPE GAME WITH MULTIPLE TRACKS - The play of roulette-type game is made more enticing by offering for a single bet a range of payouts from very modest with a high frequency to very great with low frequency. This is achieved without changing the underlying roulette-type game. In a twelve-position roulette, six balls can be used to provide over a 30% chance of getting a match, while the very low probability of getting 3 or more matches provides for generous payouts. Bets can also be placed on patterns of positions of balls. | 05-12-2011 |
20120009987 | SYSTEM FOR MONITORING THE STATE OF BINGO GRIDS - The present invention relates to a system for operating a bingo game. Play cells are organized into a pair of linked M×N grids, where each one of M and N is greater than two. Each one of the play cells bears one of a predetermined set of symbols. At least some of the symbols are selected by a means for randomly selecting different symbols from the set. The symbol selection designates the play cells to be daubed. A predetermined pattern spanning two grids is displayed by a means for displaying the pattern. The pattern is to be formed by combining different sub-patterns formed within each of the linked grids using the daubed play cells. | 01-12-2012 |
Marta Zamfir, Bucuresti RO
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20100259622 | Determination of need to service a camera based on detection of blemishes in digital images - A method of automatically determining a need to service a digital image acquisition system including a digital camera with a lens assembly includes analyzing pixels within one or more acquired digital images according to probability determinations that such pixels correspond to blemish artifacts. It is automatically determined whether a threshold distribution of blemish artifacts is present within one or more of the digital images. A need for service is indicated when at least the threshold distribution is determined to be present. | 10-14-2010 |
20100321537 | Image Defect Map Creation Using Batches of Digital Images - A method of automatically determining a need to service a digital image acquisition system including a digital camera with a lens assembly includes analyzing pixels within one or more acquired digital images according to probability determinations that such pixels correspond to blemish artifacts. It is automatically determined whether a threshold distribution of blemish artifacts is present within one or more of the digital images. A need for service is indicated when at least the threshold distribution is determined to be present. | 12-23-2010 |
20130208995 | Image Defect Map Creation Using Batches of Digital Images - A method of automatically determining a need to service a digital image acquisition system including a digital camera with a lens assembly includes analyzing pixels within one or more acquired digital images according to probability determinations that such pixels correspond to blemish artifacts. It is automatically determined whether a threshold distribution of blemish artifacts is present within one or more of the digital images. A need for service is indicated when at least the threshold distribution is determined to be present. | 08-15-2013 |
Marta Zarandi, Miami Beach, FL US
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20100092539 | Fluorinated GHRH Antagonists - Novel fluorinated synthetic analogs of hGH-RH(1-30)NH | 04-15-2010 |
20110066230 | Fluorinated GHRH Antagonists - Novel fluorinated synthetic analogs of hGH-RH(1-30)NH | 03-17-2011 |
20130261055 | Novel N- and C- terminal substituted antagonistic analogs of GH-RH - There is provided a novel series of synthetic analogs of hGH-RH(1-29)NH | 10-03-2013 |
Márta Agoston, Budapest HU
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20100075975 | MEDICAMENT FOR THE ENHANCEMENT OF COGNITIVE FUNCTION AND NEUROPROTECTION - The invention relates the use of 4-chloro-5-{2-[4-(6-fluoro-1,2-benz[d]isoxazole-3-yl)piperidin-1-yl]ethyl-amino}-2-methyl-3-(2H) pyridazinone of the Formula (I) | 03-25-2010 |
Márta Kabai Jánosné, Budapest HU
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20130140980 | FLUORESCENT LAMP OF IMPROVED LUMEN MAINTENANCE AND MERCURY CONSUMPTION - The inner surfaces of fluorescent lamp tubing are provided with a phosphor coating. The phosphor coating defines an inward-facing surface. A protective coating is deposited on the inward-facing surface of the phosphor coating. The protective coating defines an innermost surface and makes effective recombination of Hg ions possible on the innermost surface of the second coating before the Hg ions collide with the phosphor particles in the phosphor coating. | 06-06-2013 |
Márta Kabai Jánosné, Budapest HU
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20130140980 | FLUORESCENT LAMP OF IMPROVED LUMEN MAINTENANCE AND MERCURY CONSUMPTION - The inner surfaces of fluorescent lamp tubing are provided with a phosphor coating. The phosphor coating defines an inward-facing surface. A protective coating is deposited on the inward-facing surface of the phosphor coating. The protective coating defines an innermost surface and makes effective recombination of Hg ions possible on the innermost surface of the second coating before the Hg ions collide with the phosphor particles in the phosphor coating. | 06-06-2013 |
Márta Porcs-Makkay, Pomáz HU
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20090215757 | Process for Preparation of High-Purity Meloxicam and Meloxicam Potassium Salt - The invention provides a process for the preparation of high purity meloxicam of the Formula (II). The meloxicam raw product is reacted with the solution of potassium hydroxide or potassium carbonate, whereby high purity meloxicam potassium salt monohydrate is produced. Said salt is subsequently treated with mineral or organic acid to yield high-purity meloxicam. | 08-27-2009 |
Márta Porcs-Makkay, Pomaz HU
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20110040093 | PROCESS FOR THE PREPARATION OF PHARMACEUTICAL INTERMEDIATE - The invention relates to a process for the preparation of compounds of general formula (III), wherein R represents fluorine or chlorine atom and X represents chlorine or bromine atom, by halogenation of cyclopropyl benzyl ketone of general formula (II), wherein R represents fluorine or chlorine atom and the halogenation is carried out in the mixture of aqueous hydrogen halide and aqueous hydrogen peroxide in the presence of a water miscible solvent or in the presence of a phase transfer catalyst; or the halogenation is carried out in the mixture of sulfuric acid and an alkali metal salt of aqueous hydrogen halide. The process can be applied preferably on industrial scale. | 02-17-2011 |
20120035162 | PROCESS FOR PREPARATION OF HIGH-PURITY MELOXICAM AND MELOXICAM POTASSIUM SALT - The invention provides a process for the preparation of high purity meloxicam of the Formula (II). The meloxicam raw product is reacted with the solution of potassium hydroxide or potassium carbonate, whereby high purity meloxicam potassium salt monohydrate is produced. Said salt is subsequently treated with mineral or organic acid to yield high-purity meloxicam. | 02-09-2012 |
20120108607 | OPTICALLY ACTIVE 3-[(PHENYLPIPERAZIN-1-YL)ALKYL]-3- ALKYL-OXINDOLE DERIVATIVES HAVING CNS ACTIVITY - The present invention relates to the enantiomers of 5,7-dichloro-3-{4-[4-(4-chlorophenyl)-piperazin-1-yl]butyl}-3-ethyl-1,3-dihydro-2H-indol-2-one of the Formula (II) pharmaceutically acceptable salts thereof, process for the preparation thereof, medicinal products containing said enantiomers and the use thereof and their pharmaceutically acceptable salts in the treatment of the disorders of the central nervous system. | 05-03-2012 |
20120330018 | PROCESS FOR PREPARING PHARMACEUTICAL COMPOUNDS AND INTERMEDIATE COMPOUNDS - The object of the present invention is a process for preparing the 2-acetoxy-5-(2-fluor-α-cyclopropyl-carbonyl-benzyl)-4,5,6,7-tetrahydro-4H-tieno[3,2-c]pyridine (prasugrel) of the formula (I). The process starts form crystalline 5-trityl-4,5,6,7-tetrahydro-tieno[3,2-c]pyridine of the formula (VI). Further objects of the present invention are two novel crystalline forms of 5-trityl-4,5,6,7-tetrahydro-tieno[3,2-c]pyridine of the formula (VI) and the use thereof for preparing the compound of the formula (V) and process preparing thereof. | 12-27-2012 |
20130030183 | PROCESS FOR PREPARING A PHARMACEUTICAL COMPOUND - The object of the present invention is a one-pot process for preparing the 2-acetoxy-5-(2-fluoro-α-cyclopropyl-carbonyl-benzyl)-4,5,6,7-tetrahydro-4H-tieno[3,2-c]-pyridine (prasugrel) of the formula (I) by reacting the 5,6,7,7a-tetrahydro-4H-tieno[3,2-c]-pyridine-2-on of the formula (II) with 2-bromo-1-cyclopropyl-2-(2-fluorophenyl)-etanone of the formula (III) or with 2-chloro-1-cyclopropyl-2-(2-fluorphenyl)-etanone of the formula (IIIa) and acetylating of the formed compound of the formula (IV), wherein the reaction is carried out in the presence of an organic base with an acetylation agent without isolating the compound of the formula (IV). The coupling and acetylation are carried out in the presence of the same organic base such as triethylamine, N,N-diisopropyl-ethylamine or pyridine. At the end of the process the prasugrel of the formula (I) is purified by recrystallization from an organic solvent or a mixture of solvents. | 01-31-2013 |
Márta Széll, Szeged HU
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20100297648 | METHOD FOR DIAGNOSING SUSCEPTIBILITY TO POST-TRAUMATIC SCAR-TISSUE FORMATION - Disclosed is an in vitro method for diagnosing susceptibility to post-traumatic scar tissue formation, wherein from a biological sample of a patient the nucleotide of the -509 position of the TGF-β1 gene is determined and if said -509 position contains exclusively C, thus it is the homozygotic wild type allele, then said patient is considered to be susceptible to post-traumatic scar tissue formation. The invention relates furthermore to diagnostic kits for the detection of susceptibility to post-traumatic scar tissue formation, preferably for the detection of susceptibility to tracheal stenosis from a biological sample. | 11-25-2010 |
Márta Széll, Szeged HU
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20100297648 | METHOD FOR DIAGNOSING SUSCEPTIBILITY TO POST-TRAUMATIC SCAR-TISSUE FORMATION - Disclosed is an in vitro method for diagnosing susceptibility to post-traumatic scar tissue formation, wherein from a biological sample of a patient the nucleotide of the -509 position of the TGF-β1 gene is determined and if said -509 position contains exclusively C, thus it is the homozygotic wild type allele, then said patient is considered to be susceptible to post-traumatic scar tissue formation. The invention relates furthermore to diagnostic kits for the detection of susceptibility to post-traumatic scar tissue formation, preferably for the detection of susceptibility to tracheal stenosis from a biological sample. | 11-25-2010 |