Nawroth
Isabel Nawroth, Arhus C DK
Patent application number | Description | Published |
---|---|---|
20120040004 | TREATMENT OF RADIATION-INDUCED FIBROSIS - The present invention relates to treatment or prevention of radiation induced fibrosis using TNF-alpha antagonism. Preferably, TNF-alpha is antagonized by direct binding or by inhibition of synthesis. In a preferred embodiment, the invention comprises intraperitoneal administration of a chitosan-siRNA nanoparticle, wherein the siRNA is targeted to the mRNA encoding TNF-alpha. | 02-16-2012 |
Janna C. Nawroth, Boston, MA US
Patent application number | Description | Published |
---|---|---|
20150182679 | TISSUE-ENGINEERED PUMPS AND VALVES AND USES THEREOF - The present invention provides tissue-engineered pumps and valves, methods of fabricating such pumps and valves, and methods of use of such pumps and valves. | 07-02-2015 |
Manfred Nawroth, Wipperfurth DE
Patent application number | Description | Published |
---|---|---|
20080258338 | POLYCARBONATE MOLDING COMPOSITIONS - The invention relates to talcum-reinforced polycarbonate compositions comprising: A) a polycarbonate, polyester carbonate or a mixture thereof, B) optionally, at least one polymer selected from one of the group consisting of graft polymer produced in an emulsion polymerisation process, graft polymer produced in a bulk polymerisation process, rubber-free vinyl homopolymer and rubber-free vinyl copolymer, C) talcum, D) a Brönstedt acid, and optionally E) at least one polymer additive, and wherein the composition is free of aromatic or partially aromatic polyesters. Compared to the known prior art the inventive compositions have an improved ductility, thermal resistance towards deformation and thermal stability during compounding and processing (molding). The invention also provides for the use of the composition for the production of molded articles and two-component structural parts. | 10-23-2008 |
20120100377 | STRESS CRACKING-RESISTANT AND LOW-WARPAGE TWO-COMPONENT MOLDED PARTS COMPRISING TALCUM - The invention relates to ductile and low-warpage, that is to say dimensionally stable, two-component molded parts which are stress cracking-resistant with respect to the influence of chemicals. | 04-26-2012 |
20130280452 | SEAMLESS TAILGATE - The invention relates to a method for producing seamlessly manufactured vehicle components, in particular vehicle flaps, having a continuous support of a thermoplastic plastics material, which vehicle components have at least one transparent region that is an integral part of the support. | 10-24-2013 |
Manfred Nawroth, Wipperfuerth DE
Patent application number | Description | Published |
---|---|---|
20110171459 | TWO-COMPONENT MOULDING PARTS WHICH ARE RESISTANT TO STRESS CRACKING AND WARPING, CONTAINING A PLATELET-LIKE OR FLAKED INORGANIC FILLER WITH THE EXCEPTION OF TALCUM - The invention relates to ductile two-component moulding parts which are resistant to stress cracking and warping under the influence of chemicals, i.e. dimensionally stable two-component moulding parts. | 07-14-2011 |
Peter Nawroth, Leimen DE
Patent application number | Description | Published |
---|---|---|
20120115789 | Methylglyoxal-Scavenging Compounds and Their Use for the Prevention and Treatment of Pain and/or Hyperalgesia - The present invention relates to compounds which inhibit or antagonize the binding of methylglyoxal (MG) and/or other reactive carbonyl species (RCS) to an arginine- or lysine- containing protein, preferably an arginine- or lysine-containing cellular protein, such as a sodium ion channel, e.g. the sodium ion channel Na(v)1.8. Preferred scavenger compounds are peptides comprising several or multiple repeats of the amino acid sequence motif Gly-Glu-X-Pro (GEXP), wherein X is Arg or Lys, and pharmaceutical compositions thereof. The present invention furthermore relates to the use of the compounds as scavenger or antagonists of methylglyoxal and/or related reactive carbonyl species (RCS). The present invention furthermore relates to the use of the compounds for the prevention and/or treatment of pain, hyperalgesia and pain related diseases, in particular pain and/or hyperalgesia caused by or associated with methylglyoxal and/or reactive carbonyl species (RCS). | 05-10-2012 |
Thomas Nawroth, Langenlonsheim DE
Patent application number | Description | Published |
---|---|---|
20140350323 | Particulate System For Use in Diminishing Cell Growth/Inducing Cell Killing - The Invention relates to a particulate system for use in diminishing cell growth, in particular the growth of cancer cells, comprising one or more water soluble lanthanide compounds that are embedded in a solid biodegradable polymer particle, the polymer being selected from the group consisting of polycarbonic acids, polylactic acids, polyglycolic acids, polypeptides or combinations thereof. | 11-27-2014 |