Gregory, GB
Brian Gregory, Dartford GB
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20100285968 | THERMAL CONTRACTION COMPENSATION FOR SUPERCONDUCTING AND CRYO-RESISTIVE CABLES - A method of compensating for thermal contraction of superconducting and cryo-resistive cables. The method includes the steps of determining a compensation length for a cable such that when the cable is subjected to an operating temperature, the cable is in or near a stress-free state, and installing the cable into a pipe such that portions of the cable extend outwardly past ends of the pipe. The method further includes the steps of marking each end of the cable such that the determined compensation length is visibly shown, forcing the cable into the pipe at an ambient installation temperature such that a cable pattern is formed therein, and maintaining the cable in the pipe to prevent the cable from being pushed out of the pipe. | 11-11-2010 |
20140123481 | THERMAL CONTRACTION COMPENSATION FOR SUPERCONDUCTING AND CRYO-RESISTIVE CABLES - A cable insertion tool for installing thermally compensated superconducting and cryo-resistive cables is disclosed. The cable insertion tool includes a guide tube adapted to engage a pipe and to prevent a cable positioned therein from buckling, a cross-bar adapted to move along the guide tube and engage an end of the cable positioned therein, and a cable drive apparatus operably connected to the cross-bar. The cable drive apparatus is adapted to move the cross-bar such that the cable positioned in the guide tube is forced into the pipe. | 05-08-2014 |
Bruce Gregory, London GB
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20120227485 | Balanced and Eccentric Mass Compact Pendulum with Dynamic Tuning - A pendulum combining balanced and eccentric masses oscillates with a period that is rapidly and continuously varied by shifting the balanced masses and eccentric mass to and from the rotational axis, by controlling the amplitude of oscillation and, in a rolling embodiment, by varying the curvature of the rolling surface. Long period oscillations can be achieved without the large heights required by an equivalent conventional pendulum. The pendulum can be substantively isochronous. The pendulum can be applied to harvesting vibrational energy and especially to wave energy extraction by dynamically achieving resonance over the typical frequency range of energetic ocean swell. | 09-13-2012 |
20140117671 | Dynamic Tuning for Wave Energy Conversion - Wave energy converter efficiency is improved by dynamic tuning over periods from 5 to 15 seconds. Tuning methods are: for heaving, mass is varied by locking and unlocking neutrally buoyant masses or by trapping and releasing seawater; for surging, water-plane area is varied by force; for rotational variants of heaving and surging and for pitching, the radius of gyration is varied. Fixed mass is reduced by using materials and structures with high ratios of strength to weight. Fixed added mass is reduced by streamlining, by constant radius body profiles and by keeping moving structures out of the water. Added mass is varied continuously by using variable angle fins: effectiveness is enhanced by enclosure. In pitching, wave-bridging is addressed by limiting length, using locking and unlocking segments of the floating body or by using gravity as the restoring force. Solutions are described for heaving, surging, pitching and wave-following. | 05-01-2014 |
20150047805 | Heat Transfer Through Interior Cladding of Living Spaces - The efficiency of radiant space heating or cooling is improved and the use of renewable energy sources enabled by reducing the resistance of the thermal path through cladding used in the floor, walls or ceiling of a domestic or commercial living space. The resistance of the thermal path is reduced by constructing the cladding with an array of thermal bridges each comprising a thermal shunt connected to a heat-collecting layer and to a heat-dispersing layer. Such bridged cladding extends the range of choice of interior cladding and of configuration of radiant system. | 02-19-2015 |
20150136361 | Heat Transfer Using Flexible Fluid Conduit - Heat transfer between a fluid-bearing flexible tube and a heat-conducting surface is improved by fixing a flexible heat-conducting sheath to the flexible tube and by compressive fixing that distorts the tube and deforms the sheath and/or the surface. The tube can be made of cross-linked polythene (PEX). The sheath can be spirally wound high-purity aluminum wire. The sheath enables efficient heat transfer between the outer surface of the tube and the heat-conducting surface. Applications include radiant heating and cooling. Tube layout can be customized and variable tube spacing is possible, for example by using a castellated layer to support the tube. | 05-21-2015 |
Carl Gregory, Cowes GB
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20160040654 | METHOD OF DE-ICING A WIND TURBINE BLADE - A method of de-icing a wind turbine blade ( | 02-11-2016 |
Christopher Gregory, Edinburgh GB
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20100285034 | METHOD - Described are methods of separating viable cells, apoptotic cells and dead cells and antibodies or use in such methods. The antibodies may also be used in treatment of inflammatory disease, cancer and in wound healing. | 11-11-2010 |
20110182914 | METHODS AND COMPOSITIONS - The invention relates to methods for modulating granulocyte activation and migration, use of such methods in the treatment of diseases and compositions which may be employed in such methods and uses. In particular, the modulation of granulocyte activation/migration is achieved by increasing or decreasing the amount of lactoferrin in the vicinity of said granulocytes. | 07-28-2011 |
20110256581 | CELL SEPARATION TECHNIQUE - In a first aspect, the present invention provides a method of removing non-viable cells from a cell population, said method comprising contacting a cell population with a compound under conditions suitable to permit binding between the compound and any non-viable cells present in the cell culture and removing at least some of the compound from said cell population. The invention further provides compositions suitable for use in these methods, further uses of such compositions and various other systems and kits. | 10-20-2011 |
Christopher D. Gregory, Edinburgh GB
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20080305043 | Assay Method - Described is a method of detecting non-viable cells in a sample of cells, the method comprising contacting a sample of the cells with a detectable reagent and detecting binding of said reagent to cells of said sample. The detectable reagent is milk, a milk product or component thereof. A component which may be used is a lipopolysaccharide-binding protein, for example lactoferrin. The method may be performed in low Ca | 12-11-2008 |
Denis James Gregory, Bebington GB
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20140057827 | FABRIC CONDITIONERS - An aqueous fabric conditioner composition comprising (a) from 2 to 9 wt % of a fabric softening active, by weight of the total composition, wherein the fabric softening active is an ester-linked quaternary ammonium compound having fatty acid chains comprising from 20 to 35 wt % of saturated C18 chains and from 20 to 35 wt % of monounsaturated C18 chains, by weight of total fatty acid chains; and (b) from 0.01 to 0.5 wt %, by weight of the total composition, of a floc prevention agent, which is a non-ionic alkoxylated material having an HLB value of from 8 to 18, wherein the aqueous fabric conditioner composition has a viscosity of greater than 50 cps, preferably from 55 to 200 cps as measured on a cup and bob viscometer; the viscosity being continuously measured under shear at 106 s″1 for 60 seconds, at 25° C. and wherein the composition leads to little or no floc formation upon addition to water. | 02-27-2014 |
Donald Peter Gregory, Wirral GB
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20100226865 | TOOTHPASTE COMPOSITION - A toothpaste composition comprising a surfactant, an abrasive, a humectant, triglyceride oil, a carboxylated polysaccharide, and a sulphated or sulphonated polysaccharide and the use of a sulphated or sulphonated polysaccharide, in particular a carrageenan, to improve the in-use foam quality of a toothpaste. | 09-09-2010 |
Emma Gregory, London GB
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20090274677 | ANTIOXIDANT FOR USE IN COSMETIC, MEDICATED AND PHARMACEUTICAL PREPARATIONS - The invention provides the use a 2,2-dimethyl chroman as a SOD mimetic in a cosmetic preparation. Cosmetic preparations comprising a 2,2-dimethyl chroman as a SOD mimetic are described, as well as methods for treating or preventing free radical damage to skin cells and treating or preventing hair loss which comprise topical administration of a 2,2-dimethyl chroman as a SOD mimetic. | 11-05-2009 |
George Gregory, Cambridge GB
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20150233529 | SUBFRAME FOR A VALVE BODY - The present invention provides a sub-frame ( | 08-20-2015 |
20150247589 | FLOW APPARATUS - The present invention provides a flow apparatus ( | 09-03-2015 |
George Richard Gregory, Hertfordshire GB
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20090275916 | Medication Delivery Device - The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in such medication delivery device, in particular in pen-type injectors, preferably having a dose setting member and a drive device enabling the dose setting and the administration of a medicinal product from a multi-dose medication cartridge, to methods using such device, and to methods of manufacturing and assembly of such device. | 11-05-2009 |
George Richard Gregory, Hertofrshire GB
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20100297707 | REACTION VESSEL COMPRISING CONDUCTIVE LAYER AND INNER NON-METALLIC LAYER - A reaction vessel for conducting a chemical or biochemical reaction, such as a polymerase chain reaction wherein at least one wall of said vessel comprises a metallic layer and an inner non-metallic layer. Reaction systems comprising combinations of vessels of the invention and apparatus for heating them, as well as particular reactions vessels are also described and claimed. | 11-25-2010 |
Haydn Gregory, Cambridge GB
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20100051912 | MOLECULAR ELECTRONIC DEVICE FABRICATION METHODS AND STRUCTURES - This invention generally relates to improved methods of fabricating molecular electronic devices, in particular organic electronic devices such as organic light emitting diodes (OLEDs) by droplet deposition techniques such as ink jet printing. The invention also relates to molecular device substrates fabricated by and/or use in such methods. | 03-04-2010 |
20110291084 | Display Device and Backplane - A display device comprises a plurality of electroluminescent display pixels and a plurality of semiconductor elements (“chiplets”), each pixel being electrically connected to the output of one or more of said semiconductor elements through a via hole in an electrically insulating layer for addressing the plurality of display pixels, and a plurality of colour filters and/or downconverters. The colour filters and/or downconverters and the semiconductor elements are provided on the same surface of the device. | 12-01-2011 |
20110291572 | Display Drivers - An active matrix display comprises a display area of the matrix comprising drive circuitry including a control circuit comprising chiplets outside the display area. The output of the control circuit is distributed among the plurality of chiplets. This arrangement is advantageous in that the chiplets allow for a much smaller fan-in and fan-out structure, thus allowing a much larger percentage of the substrate to be devoted to display area. | 12-01-2011 |
20110291992 | Optical Sensor Array - An optical sensor array comprises a photo-sensitive area formed by an array of chiplets having individual light-sensitive elements, each element configured to produce a signal or signals in response to incident light. The displacement of a chiplet from a predetermined position is derivable from the output signal or signals of the element or elements associated with the chiplet. The arrangement provides a method of measuring the displacement of at least one chiplet in an active display. | 12-01-2011 |
Haydn Gregory, Swindon GB
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20130277649 | ORGANIC ELECTRONIC DEVICE STRUCTURES AND FABRICATION METHODS - An organic electronic device structure, the structure comprising: a substrate; a base layer supported by said substrate and defining the base of a well for solvent-based deposition of organic electronic material; one or more spacer layers formed over said base layer; a bank layer formed over said spacer layer to define a side of said well; and wherein an edge of said well adjacent said base layer is undercut to define a shelf over said base layer, said shelf defining a recess to receive said organic electronic material. | 10-24-2013 |
Ian Stephen Gregory, Cambridge GB
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20090200472 | THZ INVESTIGATION APPARATUS AND METHOD - Apparatus for measurement of a sample comprises means for generating electromagnetic radiation comprising a photoconductive device, the generating means is arranged to generate an output signal comprising electromagnetic radiation in dependence upon radiation received by the photoconductive device and to transmit the output signal towards a sample space, the apparatus further comprises a first radiation source and a second radiation source, arranged such that the radiation received by the photoconductive device comprises a mixture of radiation from the first radiation source and radiation from the second radiation source, control means for varying the frequency of the electromagnetic radiation of the output signal by varying the temperature of the first radiation source and/or the temperature of the second radiation source, and detecting means for detecting a response signal. | 08-13-2009 |
20090314944 | TERAHERTZ INVESTIGATIVE SYSTEM AND METHOD - A system for investigating a plurality of samples having varying positions or orientations moving with respect to the system, the system including an emitter of terahertz radiation for irradiating a sample provided in a sample space; a detector of terahertz radiation configured to detect radiation reflected from said sample space; and determining means to determine if radiation reflected from said sample space is from a sample with a predetermined orientation in the sample space. | 12-24-2009 |
Jason Nicholas Gregory, Bath GB
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20120298214 | COOLANT ADAPTER - The invention relates to an adapter for driven tools such as drilling or milling tools, for adapting an externally fed driven tool for use in a thru coolant system comprising: a) a cylindrical inner sleeve, b) an outer sleeve adapted to rotate relative to the inner sleeve, c) a delivery pipe to deliver coolant to the outer sleeve, and d) at least one coolant flow channel through the outer sleeve and through the inner sleeve to allow flow of coolant from the delivery pipe to the collet, and e) a seal at one end of the inner sleeve having an aperture to receive the cutting tool whereby to allow the blunt end of the tool to engage the collet, in use coolant can pass through the outer sleeve, through the inner sleeve into the collet, and to the cutting tool whilst said inner sleeve rotates with said machine output spindle and the outer sleeve remains static. | 11-29-2012 |
Jennifer Susan Gregory, Aberdeenshire GB
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20110243416 | MORPHOMETRY OF THE HUMAN HIP JOINT AND PREDICTION OF OSTEOARTHRITIS - Apparatus and method for analysing the morphometry of a human hip joint. The apparatus comprises:— | 10-06-2011 |
20110257507 | MORPHOMETRY OF THE HUMAN KNEE JOINT AND PREDICTION FOR OSTEOARTHRITIS - Apparatus and method for analysing the morphometry of a human knee joint. The apparatus comprises: | 10-20-2011 |
John Gregory, Manea March GB
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20140023792 | DISPENSING METHOD AND DEVICE FOR DISPENSING - A method provides a layer of a first liquid on a first area of a surface using an elongate applicator, an elongate gap being formed between the applicator and the surface, the gap being filled with an elongate globule of the first liquid, and an amount of a second liquid being arranged in contact with the applicator and with the globule, the first liquid and the second liquid being immiscible and the first area having a higher wettability for the first liquid than for the second liquid. The method includes applying a relative motion between the applicator and the surface, wherein the amount of second liquid being arranged only on a trailing side of the applicator. | 01-23-2014 |
John James Gregory, Cambridgeshire GB
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20110101317 | Electronic Devices and Methods of Making Them Using Solution Processing Techniques - A method of manufacturing an electronic device comprises: providing a base comprising circuit elements; forming a double bank well-defining structure over the base, comprising a first layer of insulating material and a second layer of insulating material thereover; and depositing a solution of organic material in the well defined by the double bank structure. The double bank well-defining structure is formed by removing material from the first and second layers in a single processing step to form the well. The first layer is made of a material which is removed at a faster rate than material of the second layer to form an overhanging step structure in which the second layer protrudes out over an edge of the first layer. | 05-05-2011 |
Jonathan M. Gregory, Cheltenham GB
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20130047618 | WALL ELEMENTS FOR GAS TURBINE ENGINES - A double-wall structure for use in components in gas turbine engines that are exposed to high temperatures has a first wall spaced apart from a second wall. The first wall has a protrusion extending therefrom towards the second wall. The second wall has a cooling fluid orifice, or hole, through which cooling fluid is directed in use towards the protrusion. The protrusion extends across a significant percentage of the gap between the first and second walls. The cooling fluid removes heat from protrusion as it flows over it through convection, thereby cooling the first wall. The cooling fluid is also redirected so as to become more aligned with the first wall as it flows over the protrusion. In some cases, a trench is provided at the base of the protrusion. The cooling fluid causes a vortex to form in the trench, thereby further assisting cooling. | 02-28-2013 |
Jonathan Mark Gregory, Gloucestershire GB
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20150082798 | COMPONENT FOR ATTACHING TO A WALL - A tile for attaching to a wall of a gas turbine engine. The tile has a main body. The tile also has a bridging structure that projects outwardly from the main body and has a hole configured to receive an elongate fastener so that the tile can be attached to the wall of the gas turbine engine by passing the elongate fastener through a hole in the wall of the gas turbine engine and the hole in the bridging structure. | 03-26-2015 |
Jonathan Mark Gregory, Cheltenham GB
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20140241871 | VANE STRUCTURE AND A METHOD OF MANUFACTURING A VANE STRUCTURE - A fuel injector comprises a swirler and the swirler comprises a plurality of vanes, a first member and a second member. The second member is arranged coaxially around the first member and the vanes extend radially between the first and second members. The vanes have leading edges and the second member has an upstream end. The leading edges of the vanes extend with radial and axial components from the first member to the upstream end of the second member and the radially outer ends of the leading edges of the vanes form arches with the upstream end of the second member. The arrangement of the swirler enables the fuel injector to be built by direct laser deposition. | 08-28-2014 |
Jonathan Philip Gregory, Hampshire GB
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20080257147 | Gas Distributor - A gas distributor, for distributing a gas that contains an entrained liquid, comprises a body with upper ( | 10-23-2008 |
Judith Ann Gregory, Fleet GB
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20160115424 | FRAGRANCE COMPOSITIONS COMPRISING IONIC LIQUIDS - The present invention relates to a fragrance composition comprising ionic liquids for enhanced evaporation of the perfume raw materials. The invention also relates to methods of use of the fragrance compositions for perfuming suitable substrates, particularly skin and hair. | 04-28-2016 |
Karl Gregory, Isle Of Wight GB
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20100163678 | THERMAL ANTI-ICING SYSTEM - An air intake duct of an aircraft engine or other component is provided with a thermal anti-icing system. The front of the air intake duct comprises a toroidal outer skin ( | 07-01-2010 |
Karl Gregory, Cowes GB
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20120246931 | METHODS OF MANUFACTURING WIND TURBINE BLADES - An elongate web is attached to the root end of a spar of a wind turbine rotor blade to provide additional support along the width of the blade. The root end is formed by a winding operation, and a recess is then cut into the surface of the spar. The recess is defined by a relatively large first, cylindrical surface, which is coaxial with the longitudinal axis of the root end, and a relatively small second, conical surface. A tapered end of the elongate web is attached within the recess of the root end using a layer of suitable adhesive and an array of pins. Resilient spacer elements are arranged within the recess so as to surround the pins. The large area of the cylindrical surface causes the tensile and compressive stresses which arise along the elongate web in use to be transmitted to the spar as shear stresses. | 10-04-2012 |
Laura Gregory, Wilts GB
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20150083067 | MARINE ENGINE LUBRICATION - A trunk piston lubricating oil composition of TBN 20 to 60 comprising (A) a high saturates low sulphur oil of lubricating viscosity in a major amount; (B) an overbased metal hydroxybenzoate detergent additive; (C) a polyisobutene succinic anhydride additive (1-7 mass %); and (D) a meta-linear pentadecyl phenol additive (10.1 to 10 mass %), the weight ratio of (D) to (C) being less than 1 and the combined treat rate of (B), (C) and (D) being 5 to 30%. The composition is useful to improve asphaltene dispersancy when lubricating a medium-speed compression-ignited marine engine fueled by a heavy fuel oil. | 03-26-2015 |
Laura Gregory, Oxfordshire GB
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20120028521 | MARINE ENGINE LUBRICATION - Trunk piston marine engine lubrication, when the engine is fueled by heavy fuel oil, is effected by a composition comprising a major amount of an oil of lubricating viscosity containing at least 50 mass % of a Group II basestock, and respective minor amounts of an overbased metal hydrocarbyl-substituted hydroxybenzoate detergent other than such a detergent having a basicity index of less than two and a degree of carbonation of 80% or greater and at least 1 mass % of a hydrocarbyl-substituted carboxylic acid, anhydride, ester or amide thereof. Asphaltene precipitation in the lubricant, caused by the presence of contaminant heavy fuel oil, is prevented or inhibited. | 02-02-2012 |
Laura Gregory, Witts GB
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20150018258 | MARINE ENGINE LUBRICATION - A detergent system that includes (i) an overbased C20-28 alkyl-substituted hydroxybenzoate Ca salt of TBN less than 250 and (ii) an overbased C14-18 alkyl-substituted hydroxybenzoate Ca salt of TBN less than 250, the wt % Ca ratio of (ii) to (i) being more than one, is used in a trunk piston marine lubricant to improve its asphaltene dispersancy when lubricating a medium-speed compression-ignited marine engine fuelled by a heavy fuel oil. | 01-15-2015 |
Laura Gregory, Marlborough GB
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20090291869 | Marine Engine Lubrication - A trunk piston marine engine lubricating oil composition for a medium-speed compression-ignited marine engine comprises, in a major amount, an oil of lubricating viscosity containing 50 mass % or more of a Group II basestock, and, in respective minor amounts, (A) an overbased metal hydrocarbyl-substituted hydroxybenzoate detergent having a basicity index of 5.5 or greater, and (B) an overbased metal hydrocarbyl-substituted hydroxybenzoate detergent having a basicity index of 2 or less. The ratio of the mass of metal in detergent (A) to the mass of metal in detergent (B) is 10 or less. | 11-26-2009 |
20090291870 | Marine Engine Lubrication - A trunk piston marine engine lubricating oil composition for a medium-speed compression-ignited marine engine comprises, in a major amount, an oil of lubricating viscosity containing 50 mass % or more of a Group II basestock, and, in respective minor amounts, (A) an overbased metal hydrocarbyl-substituted hydroxybenzoate detergent having a basicity index of 5.5 or greater, and (B) an overbased metal hydrocarbyl-substituted hydroxybenzoate detergent having a basicity index in the range of 2.1 to 5.4. The ratio of the mass of metal in detergent (A) to the mass of metal in detergent (B) is 1 or less. The trunk piston marine engine lubricating oil composition has a TBN (using ASTM D2896) of 20 to 60. | 11-26-2009 |
Laury Gregory, Oxfordshire GB
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20120028522 | MARINE ENGINE LUBRICATION - Trunk piston marine engine lubrication, when the engine is fueled by heavy fuel oil, is effected by a composition comprising a major amount of an oil of lubricating viscosity containing at least 50 mass % of a basestock containing greater than or equal to 90% saturates and less than or equal to 0.03% sulphur or a mixture thereof, and respective minor amounts of an over-based metal hydrocarbyl-substituted hydroxybenzoate detergent other than such a detergent having a basicity index of less than two and a degree of carbonation of 80% or greater and at least 1 mass % of a hydrocarbyl-substituted carboxylic acid, anhydride, ester or amide thereof. Asphaltene precipitation in the lubricant, caused by the presence of contaminant heavy fuel oil, is prevented or inhibited. | 02-02-2012 |
Lawrence Gregory, Worthing GB
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20090254958 | VIDEO SYSTEM - A network node apparatus is disclosed for the capture, storage and replay of video data at separate respective nodes of a communications network arranged to operably couple the node apparatus. The node apparatus may include a video capture node operable to capture video data and to transmit captured data via the communications network to a video storage node. The video storage node is arranged to store captured video data, and to transmit stored data via the communications network to a video replay node which renders an image therefrom. The video storage node transmits video data to the video replay node only if the content of a transmit buffer therein matches or exceeds a predetermined lower content value and the content of a receive buffer in the replay node does not exceed a predetermined upper content value. | 10-08-2009 |
Lee Gregory, Huddersfield GB
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20100137337 | CO-CRYSTALS - The present invention relates to co-crystals of cyprodinil or pyrimethanil and a co-crystal forming compound which has at least one organic acid functional group. In particular, the present invention relates to co-crystals of cyprodinil and benzoic acid, succinic acid, fumaric acid, maleic acid, oxalic acid, pyrazine carboxylic acid, glycolic acid, levulinic acid, (2-methylphenoxy)acetic acid, hexanedioic acid, 4-(methylamino) benzoic acid, trimethyl acetic acid, pyruvic acid or 4-hydroxy-4′-biphenyl carboxylic acid. | 06-03-2010 |
Lee Garry Gregory, Huddersfield GB
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20130040869 | MILD TO THE SKIN, FOAMING DETERGENT COMPOSITION - A mild to the skin, foaming detergent composition comprising: a) 1 to 20 wt % sophorolipid biosurfactant, b) 1 to 20 wt % of anionic surfactant selected from the group consisting of glycinate, sulphosuccinate, and mixtures thereof, c) 0 to 10 wt % foam boosting surfactant, d) 0 to 2 wt % additional electrolyte, e) 0 to 10 wt % additional additives, f) 40 to 98 wt % water. The anionic surfactant is preferably disodium laureth-3-sulphosuccinate. The electrolyte may be sodium chloride, the foam boosting surfactant may be olivamidopropyl betaine and the additional additives may be silicones, polymers, structurants, thickeners or pH adjusters. A preferred additive is a dispersed modified cellulose biopolymer as structurant. The composition is suitable for personal wash, shower gel and shampoo formulations. | 02-14-2013 |
Mark Gregory, Warwick GB
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20140047365 | ASSOCIATING ANCILLARY INFORMATION WITH AN APPLICATION USER INTERFACE - Associating user interface elements with information ancillary to said user interface elements includes creating one or more items of user interface element ancillary information, receiving a request for user interface element ancillary information, the request identifying the context in which the information is to be used, searching, using a processor, said one or more items of user interface element ancillary information for items matching the context in which the information is to be used, and returning one or more items of user interface element ancillary information matching the context in which the information is to be used. | 02-13-2014 |
Matthew Alan Gregory, Cambridge GB
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20080287482 | Production of Polyketides and Other Natural Products - The present invention relates to production of polyketides and other natural products and to libraries of compounds and individual novel compounds. One important area is the isolation and potential use of novel FKBP-ligand analogues and host cells that produce these compounds. The invention is particularly concerned with methods for the efficient transformation of strains that produce FKBP analogues and recombinant cells in which cloned genes or gene cassettes are expressed to generate novel compounds such as polyketide (especially rapamycin) FKBP-ligand analogues, and to processes for their preparation, and to means employed therein (e.g. nucleic acids, vectors, gene cassettes and genetically modified strains). | 11-20-2008 |
20110165633 | Production of Polyketides and Other Natural Products - The present invention relates to production of polyketides and other natural products and to libraries of compounds and individual novel compounds. One important area is the isolation and potential use of novel FKBP-ligand analogues and host cells that produce these compounds. The invention is particularly concerned with methods for the efficient transformation of strains that produce FKBP analogues and recombinant cells in which cloned genes or gene cassettes are expressed to generate novel compounds such as polyketide (especially rapamycin) FKBP-ligand analogues, and to processes for their preparation, and to means employed therein (e.g. nucleic acids, vectors, gene cassettes and genetically modified strains). | 07-07-2011 |
20120251581 | Novel Compound and Methods for its Production - There is provided inter alia a compound of formula (I): | 10-04-2012 |
20120295841 | Sanglifehrin Based Compounds - There are provided inter alia compounds of formula (I) | 11-22-2012 |
20140038885 | Macrocyclic Compounds and Methods for Their Production - There is provided inter alia compounds of formula (I): | 02-06-2014 |
20140080837 | Sanglifehrin Derivatives and Methods for Their Production - There are provided inter alia compounds of formula (I) and (II) | 03-20-2014 |
20140234414 | Novel Dosage Form - There is provided inter alia a pharmaceutical dosage form for oral administration comprising a sanglifehrin as active ingredient in which the sanglifehrin active ingredient is protected from acid degradation in the stomach environment following oral administration. | 08-21-2014 |
20150210714 | NOVEL RAPAMYCIN ANALOGUE - There is provided inter alia a compound of formula (I) or a pharmaceutically acceptable salt thereof and its use in therapy. | 07-30-2015 |
20150266896 | PRODUCTION OF POLYKETIDES AND OTHER NATURAL PRODUCTS - The present invention relates to production of polyketides and other natural products and to libraries of compounds and individual novel compounds. One important area is the isolation and potential use of novel FKBP-ligand analogues and host cells that produce these compounds. The invention is particularly concerned with methods for the efficient transformation of strains that produce FKBP analogues and recombinant cells in which cloned genes or gene cassettes are expressed to generate novel compounds such as polyketide (especially rapamycin) FKBP-ligand analogues, and to processes for their preparation, and to means employed therein (e.g. nucleic acids, vectors, gene cassettes and genetically modified strains). | 09-24-2015 |
Matthew Alan Gregory, Essex GB
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20090253732 | Production Of Polyketides And Other Natural Products - The present invention relates to production of polyketides and other natural products and to libraries of compounds and individual novel compounds. Therefore in aspect the present invention provides 17-desmethylrapamycin and analogues thereof, methods for their production, including recombinant strains, and isolation and uses of the compounds of the invention. In a further aspect the present invention provides for the use of 17-desmethylrapamycin and analogues thereof in the induction or maintenance of immunosuppression, the stimulation of neuronal regeneration or the treatment of cancer, B-cell malignancies, fungal infections, transplantation rejection, graft vs. host disease, autoimmune disorders, diseases of inflammation vascular disease and fibrotic diseases, and in the regulation of wound healing. | 10-08-2009 |
20100061994 | MEDICAL USES OF 39-DESMETHOXYRAPAMYCIN AND ANALOGUES THEREOF - The present invention relates to medical uses of 39-desmethoxyrapamycin analogues. | 03-11-2010 |
Richard Gregory, Cambridge GB
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20120061372 | IRON - The invention relates to an electrical iron. An iron comprises a sole plate ( | 03-15-2012 |
20140097170 | Iron - The invention relates to an electrical iron. An iron comprises a sole plate, of a glass or ceramic substrate bearing an electrical heating element. The electrical heating element comprises a transparent or translucent antimony tin oxide thin film which directly heats the glass or ceramic substrate. | 04-10-2014 |
Richard George Gregory, Hertfordshire GB
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20110065150 | REACTION VESSEL COMPRISING ELECTRICALLY CONDUCTING POLYMER AS A HEATING ELEMENT - A reaction vessel for conducting a chemical or biochemical reaction, such as a polymerase chain reaction wherein electrically conducting polymer is arranged to act as a heating element. The profile of the electrically conductive polymer differs in different regions of the vessel so as to control thermal gradients. The profile of the electrically conductive polymer may be arranged to either increase or reduce the thermal gradient. Reaction systems comprising combinations of vessels of the invention and apparatus for heating them, as well as particular reactions vessels are also described and claimed. | 03-17-2011 |
Sarah-Jayne Gregory, Yorkshire GB
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20140107081 | SALICYLIC ACID TOPICAL FORMULATION - Topical skin treatment formulation containing salicylic acid or a derivative thereof, dissolved in a solvent system comprising (i) dimethyl isosorbide; (ii) a C1 to C9 alkyl salicylate; and (iii) a glyceryl fatty acid ester. The solvent system may also comprise an alcohol, a polyoxyalkylene-based solvent, and/or a C1 to C4 alkyl glucose ester. The formulation may be used in the treatment of acne. The solvent system improves the targeted delivery of the salicylic acid or derivative to relevant sites on the skin. | 04-17-2014 |
Sara Jayne Gregory, West Yorkshire GB
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20150098985 | WOUND DRESSINGS FOR THE CONTROLLED RELEASE OF THERAPEUTIC - A wound dressing material for controlled activation of a wound healing therapeutic compound in the presence of a protease enzyme in a wound fluid, the material comprising: a medically acceptable polymer; a wound healing therapeutic agent; an inhibitor of the protease enzyme; and a linker group which is cleavable by the protease enzyme, wherein the activities of both the wound healing therapeutic agent and the inhibitor are increased by contacting the wound dressing material with a would fluid containing the protease enzyme. For example, the enzyme may be a matrix metalloproteinase, the therapeutic agent may be a reactive oxygen scavenger, and the inhibitor may be a tissue inhibitor of metalloproteinase (TIMP). | 04-09-2015 |
Stephen Gregory, Pontypridd GB
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20090064751 | Pressing System - Apparatus for pressing blanks in a coining, stamping or press forming operation includes a rotary pressing table to which the blanks are fed, a store receptacle for the blanks and a feed system for feeding the blanks dispensed from the store receptacle to the rotary pressing table. The feed system has a guide conduit into which the blanks pass following dispensing from the store receptacle and along which the blanks are urged to file one behind another to an exit from the guide conduit. The blanks pass directly from the conduit into a receiving station of the rotary pressing table. | 03-12-2009 |
Stuart Douglas Gregory, Llandulas GB
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20110191933 | ATTACHMENT SYSTEMS - An attachment system principally use on garment ( | 08-11-2011 |
Thomas Matthew Gregory, Cambrideshire GB
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20100060776 | SHAPE MEMORY ALLOY ACTUATION APPARATUS - A miniature camera lens actuation apparatus comprises a support structure, a camera lens element supported on the support structure by a suspension system; and an SMA actuator connected between the support structure and the movable element to drive movement of the camera lens element. The control circuit may include a drive circuit and a sensor circuit which have separate electrical connections to the SMA actuator to reduce the impact of the resistance of the electrical connections on the sensing. The control circuit may vary the drive signal in response to a temperature signal indicative of the ambient temperature. An endstop limits movement to prevent extension of the SMA actuator in its unheated state beyond a maximum length which is at or below the length corresponding the local maximum resistance of the resistance-length curve. Control of position is effected using resistance of the SMA actuator as a measure of position. The control employs a ‘ratcheting’ method to prevent a failure condition and an initial calibration step to derive a range of target resistance values. In manufacture, the position of a lens holder is adjusted relative to a carrier to provide focussing on the image sensor of an image of an object at a distance in the range from infinity to the hyperfocal distance when the SMA actuator is heated to a predetermined temperature greater than ambient temperature. | 03-11-2010 |
Thomas Matthew Gregory, Cambridge GB
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20140055630 | OPTICAL IMAGE STABILISATION - A camera apparatus capable of providing optical image stabilisation comprises: a support structure; a camera unit comprising an image sensor and a lens system; a suspension system comprising a plurality of flexure elements supporting the camera unit on the support structure in a manner allowing the camera unit to tilt; and a plurality of SMA actuators. A sensor arrangement, whose output is used as the basis for generating drive signals, is mounted on the camera unit. A control circuit generates drive signals for the SMA actuators, by deriving closed-loop control signals representative of a desired degree of variation in the power of the drive signals from the output signals of the sensor arrangement without dependence on any measurement of the resistance of the SMA actuators, and generating the drive signals with powers that varies from a set-point power in correspondence with the closed-loop control signal. | 02-27-2014 |
Thomas Matthew Gregory, Cambridgeshire GB
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20110277462 | CONTROL OF A SHAPE MEMORY ALLOY ACTUATION ARRANGEMENT - An SMA actuation apparatus comprises: an SMA actuator arranged to drive movement of a movable element; a current supply supplying a drive current; a detection circuit detecting a measure of the resistance of the SMA actuator; and a control unit operative to generate a closed-loop control signal supplied to current supply for controlling the power of the drive current to drive the resistance of the SMA actuator to a target value. The control unit derives: an estimate of a characteristic temperature of the SMA actuation apparatus on the basis of the supplied power, using a thermal model; and a resistance offset on the basis thereof. The closed-loop control signal is generated on the basis of the error between the measure of the resistance of the SMA actuator and the target value of the resistance of the SMA actuator, adjusted by the resistance offset to compensate for variations in resistance. | 11-17-2011 |
Thomas Matthew Gregory, Caldecote GB
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20100275592 | CONTROL OF A SHAPE MEMORY ALLOY ACTUATION APPARATUS - An SMA actuation arrangement comprises: an SMA actuator arranged on contraction caused by heating to drive movement of a movable element relative to a support structure; a current source operative to supply drive current through the SMA actuator to heat the SMA actuator; and a detector circuit operative to detect a measure of the resistance of the SMA actuator. Whilst detecting a measure of the resistance of the SMA actuator and controlling the drive current on the basis of the measure of the resistance of the SMA actuator; there is derived a measure of an electrical characteristic of the SMA actuator that is representative of the ambient temperature. Whilst applying closed-loop control an offset is added to the control signal which reduces the steady-state value of an error between the measure of the resistance of the SMA actuator and a target value. Whilst applying open-loop control, the control signal is generated taking into account the electrical characteristics of the SMA actuator measured during a calibration stage. | 11-04-2010 |
Winter Gregory, Cambridge GB
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20100317547 | METHODS AND COMPOSITIONS - The invention relates to a complex comprising a phage particle, said phage particle comprising (i) a polypeptide; (ii) a nucleic acid encoding the polypeptide of (i); (iii) a connector compound attached to said polypeptide wherein said connector compound is attached to the polypeptide by at least three discrete covalent bonds. The invention also relates to libraries, and to methods for making complexes and to methods of screening using same. | 12-16-2010 |