Patent application number | Description | Published |
20080257088 | MANUFACTURE AND USE OF PARALLEL ECCENTRIC ELECTRO-MECHANICAL ACTUATOR - A parallel eccentric electro-mechanical actuator provides motive power and includes an electric prime mover that drives the reducer's pinion gear. This pinion drives minimum three star gears with stationary shaft bearings. Each shaft contains an eccentric which are completely in parallel with each other. These eccentrics can be thought of as parallel/in-phase driven crankshafts. Each eccentric drives the parallel eccentric (PE) gear through a bearing. The PE gear exhibits a circular motion (without rotation) which in itself is unbalanced. The crankshafts have another eccentric which create an opposite inertia force to balance that of the PE gear. The PE gear contains an external toothed gear on its periphery. It meshes with the internal teeth of the output ring gear. The relative motion between the PE gear and the ring gear is that the PE gear rolls inside the ring gear. This relative motion is called hypo-cycloidal motion. | 10-23-2008 |
20080269922 | PERFORMANCE MAPS FOR ACTUATOR INTELLIGENCE - A four level fault tolerant architecture for the intelligent machine system is based on the basic component of a self contained actuator module with standardized interfaces. This system architecture organizes all of the operational software to make it universal, high performing, fault tolerant, and use condition-based maintenance. The independent structural layers are structured and prioritized by the advanced electronic controllers. The sensor module creates an accurate parametric representation of the electro-mechanical actuator, and manages all resources in the electro-mechanical actuator. The system will also comprise of operational criteria, maximum performance envelopes, condition-based maintenance, fault tolerance, layered control, and force/motion control. The system allows independent development of different components of the framework, categorized into three levels: the management level, the servo control level, and the senor and communication level. The present disclosure establishes a fully responsive actuator whose intelligence manages a sufficiently broad set of choices. | 10-30-2008 |
20090075771 | SELF-CONTAINED ROTARY ACTUATOR - A method for providing a compact rotary action torque within a larger system comprising a cross-roller bearing, generating a controllable electromagnetic field using a motor stator while interfacing the cross-roller bearing using a bull gear. The bull gear interfaces the cross-roller bearing and includes gear-teeth. An output plate includes a ring gear and supports shaft bearings. The ring gear interfaces the output plate and includes gear-teeth. A drive shaft holds a prime mover rotor and an eccentric and associates with the output plate via the shaft bearings. A gear train includes a meshing gear having gear-teeth for meshing with the gear-teeth of the bull gear and the gear-teeth of the ring gear and walks a minimal number of the gear-teeth for each rotation of the prime mover rotor; thereby, providing a transmitting force from the prime mover along the shortest-possible transmission path. | 03-19-2009 |
20120088622 | MANUFACTURE AND USE OF PARALLEL ECCENTRIC ELECTRO-MECHANICAL ACTUATOR - A parallel eccentric electro-mechanical actuator provides motive power and includes an electric prime mover that drives the reducer's pinion gear. This pinion drives minimum three star gears with stationary shaft bearings. Each shaft contains an eccentric which are completely in parallel with each other. These eccentrics can be thought of as parallel/in-phase driven crankshafts. Each eccentric drives the parallel eccentric (PE) gear through a bearing. The PE gear exhibits a circular motion (without rotation) which in itself is unbalanced. The crankshafts have another eccentric which create an opposite inertia force to balance that of the PE gear. The PE gear contains an external toothed gear on its periphery. It meshes with the internal teeth of the output ring gear. The relative motion between the PE gear and the ring gear is that the PE gear rolls inside the ring gear. This relative motion is called hypo-cycloidal motion. | 04-12-2012 |
20120204671 | ANALYTIC INTEGRATION OF TOLERANCES IN DESIGNING PRECISION INTERFACES FOR MODULAR ROBOTICS - A robotic system providing precision interfaces between a rotary actuator and a robotic structure. The robotic structure responsive to control by a rotary actuator via a connection means whereby interface design parameters are relayed to the rotary actuator. The rotary actuator for controlling the robotic structure includes an actuator shell, an eccentric cage and a primer mover portion, rigidly attached to the eccentric cage and capable of exerting a torque on a first prime mover. A cross-roller is also included having a first bearing portion rigidly fixed to the actuator shell and a second bearing portion, an output attachment plate attached to a second bearing portion, a shell gear rigidly attached to the actuator shell, an output gear attached to the output attachment plate and an eccentric gear attached to the eccentric cage. | 08-16-2012 |
20120215450 | DISTINGUISHING BETWEEN SENSOR AND PROCESS FAULTS IN A SENSOR NETWORK WITH MINIMAL FALSE ALARMS USING A BAYESIAN NETWORK BASED METHODOLOGY - A method, system and computer program product for distinguishing between a sensor fault and a process fault in a physical system and use the results obtained to update the model. A Bayesian network is designed to probabilistically relate sensor data in the physical system which includes multiple sensors. The sensor data from the sensors in the physical system is collected. A conditional probability table is derived based on the collected sensor data and the design of the Bayesian network. Upon identifying anomalous behavior in the physical system, it is determined whether a sensor fault or a process fault caused the anomalous behavior using belief values for the sensors and processes in the physical system, where the belief values indicate a level of trust regarding the status of its associated sensors and processes not being faulty. | 08-23-2012 |
20130217530 | MANUFACTURE AND USE OF PARALLEL ECCENTRIC ELECTRO-MECHANICAL ACTUATOR - A parallel eccentric electro-mechanical actuator provides motive power and includes an electric prime mover that drives the reducer's pinion gear. This pinion drives minimum three star gears with stationary shaft bearings. Each shaft contains an eccentric which are completely in parallel with each other. These eccentrics can be thought of as parallel/in-phase driven crankshafts. Each eccentric drives the parallel eccentric (PE) gear through a bearing. The PE gear exhibits a circular motion (without rotation) which in itself is unbalanced. The crankshafts have another eccentric which create an opposite inertia force to balance that of the PE gear. The PE gear contains an external toothed gear on its periphery. It meshes with the internal teeth of the output ring gear. The relative motion between the PE gear and the ring gear is that the PE gear rolls inside the ring gear. This relative motion is called hypo-cycloidal motion. | 08-22-2013 |
20140246893 | MULTI-SPEED HUB DRIVE WHEELS - A multi-speed hub drive wheel is provided which includes a wheel equipped with a hub; a star compound gear train having first and second stages; a motor disposed in the hub which drives the wheel by way of the star compound gear train; and a clutch which switches the hub drive wheel between a first mode of operation in which the motor engages the first stage of the star compound gear train, and a second mode of operation in which the motor engages the second stage of the star compound gear train. | 09-04-2014 |
20150102655 | GEAR TRAIN AND CLUTCH DESIGNS FOR MULTI-SPEED HUB DRIVES - A multi-speed hub drive wheel (MDW) is provided. The MDW includes first and second gears; a clutch shaft having a clutch collar disposed thereon, wherein the clutch shaft drives the clutch collar between a first position in which the clutch collar engages the first gear, a second position in which the clutch collar engages the second gear, and a third position in which the clutch collar maintains the MDW in neutral; a drive shaft having a first spline disposed thereon; a clutch disk equipped with a yoke, wherein the yoke and the clutch disk slidingly engage the first spline; and a clutch motor which drives the clutch shaft. | 04-16-2015 |
20150292601 | STANDARDIZED GEAR TRAIN MODULES FOR MULTI-SPEED HUB DRIVE WHEELS - A method is provided for making a multi-speed hub drive wheel (MDW) for a vehicle. The method includes providing a set of standardized gear train modules which includes a first gear train module having a 2-speed star/epicyclic front end, a second gear train module having a 2-speed star compound back end, and a third gear train module having a single-plane star compound final stage reducer. A vehicle is selected having a set of gear train performance criteria associated therewith, and a module from the set of standardized gear train modules is incorporated into an MDW for the vehicle which meets the gear train performance criteria. | 10-15-2015 |
20150330455 | QUICK CHANGE INTERFACE FOR LOW COMPLEXITY ROTARY ACTUATOR - A rotary actuator is provided which includes a first interface surface with a plurality of apertures defined therein; a plurality of interface modules, wherein each interface module includes a first portion which releasably engages one of said apertures, and a second portion which protrudes from said first interface surface; a second interface surface which releasably mates with said first interface surface; and a gear train which rotates said first interface surface about an axis. | 11-19-2015 |
20150354667 | MODIFIED PARALLEL ECCENTRIC ROTARY ACTUATOR - A rotary actuator is provided which includes a crankshaft, a first eccentric gear disposed on a first end of the crankshaft, a second eccentric gear disposed on a second end of the crankshaft, first and second end plates, a first crosslink disposed between the first eccentric gear and the first end plate, and a second crosslink disposed between the second eccentric gear and the second end plate. The first crosslink has a first set of surface features on a surface thereof which engage a second set of surface features on the first eccentric gear, and at least one of the first and second eccentric gears is equipped with circular arc gear teeth. | 12-10-2015 |
Patent application number | Description | Published |
20140005485 | BINOCULAR VIEWING ASSEMBLY FOR A SURGICAL VISUALIZATION SYSTEM | 01-02-2014 |
20140005487 | OPTICS FOR VIDEO CAMERAS ON A SURGICAL VISUALIZATION SYSTEM | 01-02-2014 |
20140005555 | OPTICAL ASSEMBLY PROVIDING A SURGICAL MICROSCOPE VIEW FOR A SURGICAL VISUALIZATION SYSTEM | 01-02-2014 |
20140343362 | HIGHLY CORRECTED RELAY SYSTEM - A highly corrected relay system for medical endoscopes or the like is provided. The system includes a plurality of bonded lenses that are selected to provide color correction from the blue region of the spectrum through to the near infrared region of the spectrum. The system allows co-located visible and near infrared images to be resolved on a single detector. | 11-20-2014 |
20150018622 | SURGICAL VISUALIZATION SYSTEMS - A surgical device includes one or more cameras integrated therein. The view of each of the one or more cameras can be integrated together and provided to a surgeon display and/or an assistant display. A surgical tool that includes an integrated camera may be used in conjunction with the surgical device. The image produced by the camera integrated with the surgical tool may be associated with the images generated by the one or more cameras integrated in the surgical device. The position and orientation of the cameras and/or the surgical tool can be tracked, and the surgical tool can be rendered as at least partially transparent. A surgical device may be powered by a hydraulic system, thereby reducing electromagnetic interference with tracking devices. | 01-15-2015 |
20150085095 | SURGICAL VISUALIZATION SYSTEMS - A medical apparatus is described for providing visualization of a surgical site. The medical apparatus includes an electronic display disposed within a display housing, the electronic display configured to produce a two-dimensional image. The medical apparatus includes a display optical system disposed within the display housing, the display optical system comprising a plurality of lens elements disposed along an optical path. The display optical system is configured to receive the two-dimensional image from the electronic display, produce a beam with a cross-section that remains substantially constant along the optical path, and produce a collimated beam exiting the opening in the display housing. The medical apparatus can also include an auxiliary video camera configured to provide an oblique view of a patient on the electronic display without requiring a surgeon to adjust their viewing angle through oculars viewing the electronic display. | 03-26-2015 |
20150141755 | SURGICAL VISUALIZATION SYSTEMS - A surgical retractor includes a plurality of cameras integrated therein. One such retractor includes a tubular retractor and an insert supporting said plurality of cameras can be disposed within a tubular retractor. | 05-21-2015 |
20150141759 | INTERFACE FOR VIEWING VIDEO FROM CAMERAS ON A SURGICAL VISUALIZATION SYSTEM - A surgical device includes a plurality of cameras integrated therein. The view of each of the plurality of cameras can be integrated together to provide a composite image. A surgical tool that includes an integrated camera may be used in conjunction with the surgical device. The image produced by the camera integrated with the surgical tool may be associated with the composite image generated by the plurality of cameras integrated in the surgical device. The position and orientation of the cameras and/or the surgical tool can be tracked, and the surgical tool can be rendered as transparent on the composite image. A surgical device may be powered by a hydraulic system, thereby reducing electromagnetic interference with tracking devices. | 05-21-2015 |
20150238073 | SURGICAL VISUALIZATION SYSTEMS - A surgical device includes a plurality of cameras integrated therein. The view of each of the plurality of cameras can be integrated together. A surgical tool that includes an integrated camera may be used in conjunction with the surgical device. The image produced by the camera integrated with the surgical tool may be associated with the images generated by the plurality of cameras integrated in the surgical device. The position and orientation of the cameras and/or the surgical tool can be tracked, and the surgical tool can be rendered as at least partially transparent. A surgical device may be powered by a hydraulic system, thereby reducing electromagnetic interference with tracking devices. | 08-27-2015 |
20150297311 | SURGICAL VISUALIZATION SYSTEMS - A medical apparatus is described for providing visualization of a surgical site. The medical apparatus includes an electronic display disposed within a display housing, the electronic display configured to produce a two-dimensional image. The medical apparatus includes a display optical system disposed within the display housing, the display optical system comprising a plurality of lens elements disposed along an optical path. The display optical system is configured to receive the two-dimensional image from the electronic display, produce a beam with a cross-section that remains substantially constant along the optical path, and produce a collimated beam exiting the opening in the display housing. The medical apparatus can also include an auxiliary video camera configured to provide an oblique view of a patient on the electronic display without requiring a surgeon to adjust their viewing angle through oculars viewing the electronic display. | 10-22-2015 |
Patent application number | Description | Published |
20080291397 | Choroid and Retinal Imaging and Treatment System - The invention provides an apparatus, a device, and methods for imaging vasculature in a subject as well as an apparatus, a device and methods for treating abnormal vasculature in a subject. | 11-27-2008 |
20090303317 | NEAR INFRARED IMAGING - An endoscope or wand device comprising transmitting members, in which the transmitting members comprise a coating that transmits between about 95% and about 99.5% of energy at a wavelength within the infra red spectrum. | 12-10-2009 |
20110046447 | Illumination System For Variable Direction Of View Instruments - An illumination system for variable direction of view instruments is disclosed generally comprising an endoscope having a longitudinal axis and a variable view vector that pivots about a pivot axis angularly offset from the longitudinal axis. The view vector has an attendant viewing field that travels along a path as the view vector pivots, defining a viewing range. A source of illumination is arranged in a plane offset from the plane in which the view vector pivots and provides an annular, solid angle of illumination that covers the viewing range. In certain embodiments, the pivot axis is perpendicular to the longitudinal axis and the illumination plane is parallel to the pivot plane. In some embodiments, the source of illumination is a plurality of light emitting diodes arranged around the pivot axis. | 02-24-2011 |
20110249323 | COMPENSATING OPTICAL COUPLER FOR VISIBLE AND NIR IMAGING - An optical system, in particular for endoscopic applications, is disclosed which uses wavelength-compensating optical components, in particular prisms, made of materials with different inter-element coatings and refractive indices to image significantly different wavelength-ranges (VIS and NIR) onto the same image plane of an image acquisition device, such as a CCD sensor. | 10-13-2011 |
20130184591 | Near Infrared Imaging - Endoscopes and wands, useful for near infrared imaging, particularly for medical purposes, have transmitting members that transmit between about 95% and 99.9% of the energy at a wavelength within the infrared spectrum. The wands and endoscopes have at least one channel for transmitting and receiving light in the visible spectrum and at least one channel for transmitting and receiving light in the infrared spectrum. | 07-18-2013 |
Patent application number | Description | Published |
20090252733 | Generation and Profiling of Fully Human Gold-Derived Therapeutic Antibodies Specific for Human CD38 - The present invention provides novel antibodies and methods for using recombinant antigen-binding regions and antibodies and functional fragments containing such antigen-binding regions that are specific for CD38, which plays an integral role in various disorders or conditions. These methods take advantage of newly discovered antibodies and surprising properties of such antibodies, such as the ability to bind CD38 of minipig origin and the ability to induce, by cross-linking, specific killing of cells that express CD38. These antibodies as well as the novel methods for using those antibodies can be used to treat, for example, hematological malignancies such as multiple myeloma. | 10-08-2009 |
20090325290 | Human polypeptides causing or leading to the killing of cells including lymphoid tumor cells - The present invention relates to polypeptide compositions which bind to cell surface epitopes and, in multivalent forms, cause or lead to the killing of cells including lymphoid tumor cells, and in the case of monovalent forms, cause immunosuppression or otherwise inhibit activation of lymphocytes. The invention further relates to nucleic acids encoding the polypeptides, methods for the production of the polypeptides, methods for killing cells, methods for immunosuppressing a patient, pharmaceutical, diagnostic and multivalent compositions and kits comprising the polypeptides and uses of the polypeptides. | 12-31-2009 |
20100285004 | Anti-CD38 human antibodies and uses thereof - The present invention provides recombinant antigen-binding regions and antibodies and functional fragments containing such antigen-binding regions that are specific for CD38, which plays an integral role in various disorders or conditions. These antibodies, accordingly, can be used to treat, for example, hematological malignancies such as multiple myeloma. Antibodies of the invention also can be used in the diagnostics field, as well as for investigating the role of CD38 in the progression of disorders associated with malignancies. The invention also provides nucleic acid sequences encoding the foregoing antibodies, vectors containing the same, pharmaceutical compositions and kits with instructions for use. The invention also provides isolated novel epitopes of CD38 and methods of use therefore | 11-11-2010 |
20110268726 | Anti-CD38 human antibodies and uses thereof - The present invention provides recombinant antigen-binding regions and antibodies and functional fragments containing such antigen-binding regions that are specific for CD38, which plays an integral role in various disorders or conditions. These antibodies, accordingly, can be used to treat, for example, hematological malignancies such as multiple myeloma. Antibodies of the invention also can be used in the diagnostics field, as well as for investigating the role of CD38 in the progression of disorders associated with malignancies. The invention also provides nucleic acid sequences encoding the foregoing antibodies, vectors containing the same, pharmaceutical compositions and kits with instructions for use. The invention also provides isolated novel epitopes of CD38 and methods of use therefore | 11-03-2011 |
20120189622 | ANTI-CD38 HUMAN ANTIBODIES AND USES THEREOF - The present invention provides recombinant antigen-binding regions and antibodies and functional fragments containing such antigen-binding regions that are specific for CD38, which plays an integral role in various disorders or conditions. These antibodies, accordingly, can be used to treat, for example, hematological malignancies such as multiple myeloma. Antibodies of the invention also can be used in the diagnostics field, as well as for investigating the role of CD38 in the progression of disorders associated with malignancies. The invention also provides nucleic acid sequences encoding the foregoing antibodies, vectors containing the same, pharmaceutical compositions and kits with instructions for use. The invention also provides isolated novel epitopes of CD38 and methods of use therefore. | 07-26-2012 |
20130273072 | FULLY HUMAN THERAPEUTIC ANTIBODIES SPECIFIC FOR HUMAN CD38 - The present invention nucleic acids encoding novel antibodies and functional fragments thereof specific for CD38. Such antibodies are useful for the treatment of diseases associated with CD38 expression, including hematological malignancies such as multiple myeloma. | 10-17-2013 |
Patent application number | Description | Published |
20090123950 | Generation And Profiling Of Fully Human Hucal Gold.RTM.-Derived Therapeutic Antibodies Specific For Human CD38 - The present invention provides novel methods for using recombinant antigen-binding regions and antibodies and functional fragments containing such antigen-binding regions that are specific for CD38, which plays an integral role in various disorders or conditions. These methods take advantage of newly discovered antibodies and surprising properties of such antibodies, such as the ability to bind CD38 of minipig origin and the ability to induce, by cross-linking, specific killing of cells that express CD38. These antibodies as well as the novel methods for using those antibodies can be used to treat, for example, hematological malignancies such as multiple myeloma. | 05-14-2009 |
20120076782 | GENERATION AND PROFILING OF FULLY HUMAN HUCAL GOLD.RTM.-DERIVED THERAPEUTIC ANTIBODIES SPECIFIC FOR HUMAN CD38 - The present invention provides novel methods for using recombinant antigen-binding regions and antibodies and functional fragments containing such antigen-binding regions that are specific for CD38, which plays an integral role in various disorders or conditions. These methods take advantage of newly discovered antibodies and surprising properties of such antibodies, such as the ability to bind CD38 of minipig origin and the ability to induce, by cross-linking, specific killing of cells that express CD38. These antibodies as well as the novel methods for using those antibodies can be used to treat, for example, hematological malignancies such as multiple myeloma. | 03-29-2012 |
20150232571 | ANTI-CD38 HUMAN ANTIBODIES AND USES THEREFOR - The present invention provides recombinant antigen-binding regions and antibodies and functional fragments containing such antigen-binding regions that are specific for CD38, which plays an integral role in various disorders or conditions. These antibodies, accordingly, can be used to treat, for example, hematological malignancies such as multiple myeloma. Antibodies of the invention also can be used in the diagnostics field, as well as for investigating the role of CD38 in the progression of disorders associated with malignancies. The invention also provides nucleic acid sequences encoding the foregoing antibodies, vectors containing the same, pharmaceutical compositions and kits with instructions for use. The invention also provides isolated novel epitopes of CD38 and methods of use therefore. | 08-20-2015 |
Patent application number | Description | Published |
20120237498 | 4-1BB BINDING MOLECULES - The present disclosure provides isolated binding molecules that bind to human 4-1BB, nucleic acid molecules encoding an amino acid sequence of the binding molecules, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of making the binding molecules, pharmaceutical compositions containing the binding molecules, and methods of using the binding molecules or compositions. | 09-20-2012 |
20130078240 | 4-1BB BINDING MOLECULES - The present disclosure provides isolated binding molecules that bind to human 4-1BB, nucleic acid molecules encoding an amino acid sequence of the binding molecules, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of making the binding molecules, pharmaceutical compositions containing the binding molecules, and methods of using the binding molecules or compositions. | 03-28-2013 |
20140377255 | 4-1BB BINDING MOLECULES - The present disclosure provides isolated binding molecules that bind to human 4-1BB, nucleic acid molecules encoding an amino acid sequence of the binding molecules, vectors comprising the nucleic acid molecules, host cells containing the vectors, methods of making the binding molecules, pharmaceutical compositions containing the binding molecules, and methods of using the binding molecules or compositions. | 12-25-2014 |