Wang, Los Angeles
Anyou Wang, Los Angeles, CA US
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20120157339 | Molecular Markers and Assay Methods for Characterizing Cells - Disclosed herein are molecular markers and assay methods for characterizing cells. As disclosed, the methods entail determining a methylation state of at least one CpG in a region of a nucleotide molecule of the cell, comparing the methylation state with that of a corresponding CpG of a comparison cell of a known cell type, a known cell line, or a known cell strain, and distinguishing, identifying or designating the cell type, the cell line or the cell strain of the cell based on whether the methylation state is the same or different from that of the corresponding CpG. | 06-21-2012 |
Chaochao Wang, Los Angeles, CA US
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20090102708 | Navigation Receiver and Method for Combined Use of a Standard RTK System and a Global Carrier-Phase Differential Positioning System - A mobile satellite navigation receiver for calculating an offset between a local positioning system and a wide-area satellite positioning system is presented. The mobile satellite navigation receiver determines a first solution of a position of the mobile satellite navigation receiver relative to a first local positioning system, wherein the first local positioning system includes one or more reference receivers at known locations. The mobile satellite navigation receiver determines a second solution of the position of the satellite navigation receiver relative to a wide-area differential satellite positioning system. The mobile satellite navigation receiver then calculates an offset between the first solution and the second solution. | 04-23-2009 |
20100141510 | METHODS AND SYSTEMS TO INCREASE ACCURACY IN THE NAVIGATION OF SINGLE FREQUENCY RECEIVERS - In a method of mitigating errors in satellite navigation measurements at a satellite navigation receiver, respective single-frequency signals are received from respective satellites in a plurality of satellites in a satellite navigation system. Pseudorange and carrier-phase measurements corresponding to respective received single-frequency signals are calculated. These calculations include filtering the pseudorange and carrier-phase measurements in a Kalman filter having a state vector comprising a plurality of states, including a position state, a receiver clock state, and a plurality of bias states. Each bias state corresponds to a respective satellite in the plurality of satellites. The filtering includes updating the state vector. An estimated position of the satellite navigation receiver is updated in accordance with an update to the state vector. | 06-10-2010 |
20110187598 | METHOD AND SYSTEM FOR ESTIMATING POSITION USING DUAL REAL TIME KINEMATIC ENGINES - A method and system for estimating the position comprises measuring a first carrier phase of a first carrier signal and a second carrier phase of a second carrier signal received by a location-determining receiver. A primary real time kinematic (RTK) engine or receiver data processing system estimates a primary integer ambiguity set associated with at least one of the measured first carrier phase and the measured second carrier phase. A quality evaluator determines if a primary integer ambiguity set is resolved correctly to the predefined reliability rate during an earlier evaluation period. A secondary real time kinematic (RTK) engine or receiver data processing system estimates a secondary integer ambiguity set associated with at least one of the measured first carrier phase and the measured second carrier phase during a later period following the earlier evaluation period. | 08-04-2011 |
20110210889 | METHOD AND SYSTEM FOR ESTIMATING POSITION WITH BIAS COMPENSATION - A primary phase measurement device measures a first carrier phase and a second carrier phase of carrier signals received by the location-determining receiver. A secondary phase measurement device measures the third carrier phase and the fourth carrier phase of other carrier signals. A real time kinematic engine estimates a first integer ambiguity set associated with the measured first carrier phase and a second integer ambiguity set associated with the measured second carrier phase. The real time kinematic engine estimates a third ambiguity set associated with the measured third carrier phase and a fourth ambiguity set associated with the measured fourth carrier phase. A compensator is capable of compensating for the inter-channel bias in at least one of the third ambiguity set and the fourth ambiguity set by modeling a predictive filter in accordance with various inputs or states of the filter estimated by an estimator. | 09-01-2011 |
20130265192 | METHOD AND SYSTEM FOR ESTIMATING POSITION USING DUAL REAL TIME KINEMATIC ENGINES - A method and system for estimating the position comprises measuring a first carrier phase of a first carrier signal and a second carrier phase of a second carrier signal received by a location-determining receiver. A primary real time kinematic (RTK) engine or receiver data processing system estimates a primary integer ambiguity set associated with at least one of the measured first carrier phase and the measured second carder phase. A quality evaluator determines if a primary integer ambiguity set is resolved correctly to the predefined reliability rate during an earlier evaluation period. A secondary real time kinematic (RTK) engine or receiver data processing system estimates a secondary integer ambiguity set associated with at least one of the measured first carrier phase and the measured second carrier phase during a later period following the earlier evaluation period. | 10-10-2013 |
Chuan Wang, Los Angeles, CA US
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20100133511 | Integrated Circuits Based on Aligned Nanotubes - Techniques, apparatus and systems are described for wafer-scale processing of aligned nanotube devices and integrated circuits. In one aspect, a method can include growing aligned nanotubes on at least one of a wafer-scale quartz substrate or a wafer-scale sapphire substrate. The method can include transferring the grown aligned nanotubes onto a target substrate. Also, the method can include fabricating at least one device based on the transferred nanotubes. | 06-03-2010 |
20110101302 | WAFER-SCALE FABRICATION OF SEPARATED CARBON NANOTUBE THIN-FILM TRANSISTORS - Methods, materials, systems and apparatus are described for depositing a separated nanotube networks, and fabricating, separated nanotube thin-film transistors and N-type separated nanotube thin-film transistors. In one aspect, a method of depositing a wafer-scale separated nanotube networks includes providing a substrate with a dielectric layer. The method includes cleaning a surface of the wafer substrate to cause the surface to become hydrophilic. The cleaned surface of the wafer substrate is functionalized by applying a solution that includes linker molecules terminated with amine groups. High density, uniform separated nanotubes are assembled over the functionalized surface by applying to the functionalized surface a separated nanotube solution that includes semiconducting nanotubes. | 05-05-2011 |
20120261646 | Integrated Circuits Based on Aligned Nanotubes - Techniques, apparatus and systems are described for wafer-scale processing of aligned nanotube devices and integrated circuits one. In one aspect, a method can include growing aligned nanotubes on at least one of a wafer-scale quartz substrate or a wafer-scale sapphire substrate. The method can include transferring the grown aligned nanotubes onto a target substrate. Also, the method can include fabricating at least one device based on the transferred nanotubes. | 10-18-2012 |
Clay C. C. Wang, Los Angeles, CA US
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20090053769 | HETEROLOGOUS PRODUCTION OF NATURAL PRODUCTS IN BACTERIA - The present invention demonstrates an example of the de novo total biosynthesis of biologically active forms of heterologous NRPs in | 02-26-2009 |
Eric Wang, Los Angeles, CA US
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20130038230 | METHOD AND APPARATUS TO FACILITATE COUPLING AN LED-BASED LAMP TO A FLUORESCENT LIGHT FIXTURE - Methods and apparatus to facilitate coupling a light-emitting diode (LED)-based lamp to an electronic or inductive fluorescent light fixture (typically with ballast). An LED-based lamp may include circuitry that simulates an electrical behavior of a fluorescent lamp, and can be installed and operate in the fixture without any modification to the fixture. The LED-based lamp may also include one or more LEDs that are controlled by the circuitry. | 02-14-2013 |
Ganggang Wang, Los Angeles, CA US
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20090215075 | THREE-DIMENSIONAL STRUCTURE OF A DNAB-FAMILY REPLICATIVE HELICASE (G40P), USES THEREOF, AND METHODS FOR DEVELOPING ANTI-BACTERIAL PATHOGENS BY INHIBITING DNAB HELICASES AND THE INTERACTIONS OF DNAB HELICASE WITH PRIMASE - Structure and methods associated with the three-dimensional structure of G40P helicase and other structure models of any DnaB-like helicase obtained by computer modeling that bears similarity with a root-mean-square deviation (RMSD) of 2.0 with at least one of the three domain structures (N-globe, alpha-hairpin and the C-terminal ATPase domains). In one embodiment, a method for identifying a compound that binds to any fragment of a G40P protein is provided. The method including obtaining the three dimensional structure of the G40P hexamer whose sequence consists of SEQ ID NO:1 and identifying or designing one or more compounds that bind, mimic, enhance, disrupt, or compete with the G40P protein whose sequence consists of SEQ ID NO:1 or interactions of the G40P protein with its ligands based on the three dimensional structure of the G40P hexamer whose sequence consists of SEQ ID NO:1. | 08-27-2009 |
Geng Wang, Los Angeles, CA US
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20120283317 | Methods and Compositions for Regulating RNA Import into Mitochondria - Disclosed herein recombinant and/or isolated nucleic acid molecules which comprise, consist essentially of, or consist of a first nucleic acid sequence, which is a wild-type sequence or an altered sequence, directly or indirectly linked to a second nucleic acid sequence selected from the group consisting of: (1) a mitochondria localization sequence, (2) an RNA import sequence, or (3) a combination thereof, and methods of using thereof. | 11-08-2012 |
Guiqin Wang, Los Angeles, CA US
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20120119425 | ACTUATOR MOTION CONTROL FEATURES - A method for making a motion control feature for an actuator device of a type that has a moveable component coupled to an opposing fixed component for out-of-plane rotational movement relative thereto includes forming first and second flaps respectively extending from the moveable and fixed components and toward the opposing component and operable to effect one or more of damping movement of the moveable component relative to the fixed component and/or restraining movement of the moveable component relative to the fixed component in a direction substantially perpendicular to the actuator device. | 05-17-2012 |
Hanbiao Wang, Los Angeles, CA US
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20100087891 | SYSTEMS AND METHODS FOR DIAGNOSING AN IMPLANTABLE DEVICE - A method for diagnosing an implantable cardiac device including a plurality of implanted leads may include: monitoring a plurality of parameters associated with the plurality of implanted leads; detecting a change in one of the parameters; evaluating at least one of the other parameters upon detection of the change; and diagnosing a problem with the implantable cardiac device based on the detected change and the evaluation. A system for diagnosing an implantable cardiac device including a plurality of implanted leads may include an implantable pacing device and a processor. The processor may be configured to: monitor a plurality of parameters associated with the plurality of implanted leads; detect a change in one of the parameters; evaluating at least one of the other parameters upon detection of the change; and diagnose a problem with the implantable cardiac device based on the detected change and the evaluation. | 04-08-2010 |
20110106194 | SYSTEMS AND METHODS FOR USE WITH AN IMPLANTABLE MEDICAL DEVICE FOR DISCRIMINATING VT AND SVT BASED ON VENTRICULAR DEPOLARIZATION EVENT TIMING - Techniques are described for discriminating ventricular tachycardia (VT) from supraventricular tachycardia (SVT) using an implantable medical device capable of multi-site ventricular sensing. In one example, ventricular depolarization events are detected within a patient by the implantable device during a tachyarrhythmia, at both a left ventricular sensing site and a right ventricular sensing site. Ventricular event timing differences are then ascertained. The device compares the ventricular event timing differences detected during the tachyarrhythmia with predetermined supraventricular event timing differences for the patient, such as event timing differences previously detected within the patient during sinus rhythm or extrapolated from sinus rhythm values. The device then distinguishes VT from SVT based on the comparison of the event timing differences detected during the tachyarrhythmia with the predetermined supraventricular event timing differences. Morphological waveform analysis can also be performed, when needed, to further distinguish VT from SVT. | 05-05-2011 |
Hongkai Wang, Los Angeles, CA US
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20130034203 | 2D/3D REGISTRATION OF A DIGITAL MOUSE ATLAS WITH X-RAY PROJECTION IMAGES AND OPTICAL CAMERA PHOTOS - A method for preparing an image simulating the anatomy of a small subject test animal, and an apparatus for producing said image and an anatomical atlas for co-registering therewith, comprising the generation of two or more non-tomographic images of the test animals is described. Examples of the non-tomographic imaging modalities and the images generated include, but are not limited to one or more x-ray sources and resultant of x-ray projections, photographic cameras and resulting digital or optical images and surface scanners and resultant surface scans. The subject animal is positioned at a focal point in a carrier in an imaging enclosure. A combination of one or more of the non-tomographic images taken from different angles within the enclosure are combined and through an iterative process co-registered with the previously generated digital atlas of the anatomy of the same or similar test animals. | 02-07-2013 |
James Chun Wang, Los Angeles, CA US
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20130289615 | METHOD OF APPLYING A PAD TO A FOOT TO RELIEVE FOOT PAIN - The present invention is a method of applying a pad to foot to treat foot pain. The present invention includes the step of securing a pad to a precise pressure point located behind or below a painful or sore portion of a foot. The pressure resulting from the application of the pad to the pressure point of the foot relieves pain from the painful or sore portion of the foot. | 10-31-2013 |
Jianghua Wang, Los Angeles, CA US
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20100021906 | SALIVARY BIOMARKERS FOR SJOGREN'S SYNDROME - The present invention provides for the first time the identification of salivary protein and RNA factors that can be used in the detection of primary Sjögren's Syndrome. The present invention therefore provides methods of diagnosing and providing a prognosis for Sjögren's Syndrome, by examining relevant proteins (including certain autoantigens and autoantibodies) and RNA in a patient's saliva. | 01-28-2010 |
Jing-Wei Wang, Los Angeles, CA US
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20110267258 | IMAGE BASED MOTION GESTURE RECOGNITION METHOD AND SYSTEM THEREOF - An image based motion gesture recognition method and system thereof are disclosed. In embodiment, a hand posture detection is performed according to the received image frames, to obtain a first hand posture. It is then determined whether the first hand posture matches a predefined starting posture or not. If the first hand posture matches said predefined starting posture, movement tracking is performed according to hand locations on image frames, to obtain a motion gesture. During said movement tracking, the hand posture detection is performed according to said image frames to obtain a second hand posture, and it is determined whether the second hand posture matches a predefined ending posture. If the second hand posture matches the predefined ending posture, the movement tracking is stopped. Therefore, reduce complexity motion gesture recognition can be reduced and the reliability in interaction can be improved. | 11-03-2011 |
20110268365 | 3D HAND POSTURE RECOGNITION SYSTEM AND VISION BASED HAND POSTURE RECOGNITION METHOD THEREOF - A vision based hand posture recognition method and system thereof are disclosed. The method comprises the following steps of receiving an image frame; extracting a contoured hand image from said image frame; calculating a gravity center of said contoured hand image; obtaining contour points on a contour of said contoured hand image; calculating distances between said gravity center and said multiple contour points; recognizing a hand posture according to a first characteristic function of said multiple contour points. In embodiment, the finger number and hand direction of the hand posture can be determined according to the number and location of at least one peak of the first characteristic function. | 11-03-2011 |
20110298698 | MANUAL HUMAN MACHINE INTERFACE OPERATION SYSTEM AND METHOD THEREOF - A manual human machine interface operation system and method thereof are disclosed. In embodiment, this manual human machine interface operation system extracts user's arm image and palm image from the images capture by at least two cameras, and then calculates user's arm coordinate, so that user can select the object shown on the human machine interface by manually using his/her arm. The system then recognizes a hand posture according to the palm image and determines an instruction mapped to this hand posture. This instruction is then performed on the selected object. In embodiment, the hand posture can be a pointing posture, grab posture or a release posture. | 12-08-2011 |
20110299737 | VISION-BASED HAND MOVEMENT RECOGNITION SYSTEM AND METHOD THEREOF - A vision-based hand movement recognition system and method thereof are disclosed. In embodiment, a hand posture is recognized according to consecutive hand images first. If the hand posture matches a start posture, the system then separates the consecutive hand images into multiple image groups and calculates motion vectors of these image groups. The distributions of these motion vectors are compared with multiple three-dimensional motion vector histogram equalizations to determine a corresponding movement for each image group. For example, the corresponding movement can be a left moving action, a right moving action, an up moving action or a down moving action. Finally, the combination of these corresponding movements is defined as a gesture, and an instruction mapped to this gesture is then executed. | 12-08-2011 |
Jinhua Wang, Los Angeles, CA US
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20110150979 | METHODS FOR DIAGNOSIS, PROGNOSIS AND TREATMENT OF PRIMARY AND METASTATIC BASAL-LIKE BREAST CANCER AND OTHER CANCER TYPES - In one embodiment, a method of theranostic classification of a breast cancer tumor is provided, comprising obtaining a breast cancer tumor sample from a subject, detecting an expression level of FOXC1, comparing the expression level of FOXC1 to a predetermined cutoff level, and classifying the breast cancer tumor sample as belonging to a theranostic basal-like breast cancer tumor subtype or a theranostic hybrid basal-like breast cancer tumor subtype when the expression level of FOXC1 is higher than the predetermined cutoff level. In other embodiments, methods for predicting a prognosis of a basal-like breast cancer and methods of treating a basal-like breast cancer are provided, | 06-23-2011 |
20140134626 | METHODS FOR DIAGNOSIS, PROGNOSIS AND TREATMENT OF PRIMARY AND METASTATIC BASAL-LIKE BREAST CANCER AND OTHER CANCER TYPES - In one embodiment, a method of theranostic classification of a breast cancer tumor is provided, comprising obtaining a breast cancer tumor sample from a subject, detecting an expression level of FOXC1, comparing the expression level of FOXC1 to a predetermined cutoff level, and classifying the breast cancer tumor sample as belonging to a theranostic basal-like breast cancer tumor subtype or a theranostic hybrid basal-like breast cancer tumor subtype when the expression level of FOXC1 is higher than the predetermined cutoff level. In other embodiments, methods for predicting a prognosis of a basal-like breast cancer and methods of treating a basal-like breast cancer are provided. | 05-15-2014 |
20150376712 | METHODS FOR DIAGNOSIS, PROGNOSIS AND TREATMENT OF PRIMARY AND METASTATIC BASAL-LIKE BREAST CANCER AND OTHER CANCER TYPES - In one embodiment, a method of theranostic classification of a breast cancer tumor is provided, comprising obtaining a breast cancer tumor sample from a subject, detecting an expression level of FOXC1, comparing the expression level of FOXC1 to a predetermined cutoff level, and classifying the breast cancer tumor sample as belonging to a theranostic basal-like breast cancer tumor subtype or a theranostic hybrid basal-like breast cancer tumor subtype when the expression level of FOXC1 is higher than the predetermined cutoff level. In other embodiments, methods for predicting a prognosis of a basal-like breast cancer and methods of treating a basal-like breast cancer are provided, | 12-31-2015 |
Jinwen Wang, Los Angeles, CA US
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20130062285 | Oil-Tolerant Polymer Membranes for Oil-Water Separations - The invention relates to oil-tolerant water-filtration membranes comprising a microporous hydrogel coated on a porous polymeric support membrane, useful in separating hydrocarbons and hydrocarbon emulsions from a water sample. The oil-tolerant water-filtration membranes comprising a hydrophilic microporous crosslinked polymeric hydrogel coated on at least one side of a porous polymeric support membrane. The water-filtration membrane having a first face corresponding to the discrimination layer and a second face corresponding to the porous support, applying pressure to a water solution, having at least one solute, at the first face of the water-filtration membrane, and collecting purified water at the second face of water-filtration membrane. Polymeric membranes have many advantages over ceramics, including inexpensive manufacture and the ability to be manufactured into very compact (high surface area) elements. | 03-14-2013 |
Jinyi Wang, Los Angeles, CA US
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20110136252 | Integrated Microfluidics for Parallel Screening of Chemical Reactions - A microfluidic device allows for different reactions to be conducted in parallel with the use of nanoliter quantities of reagents. | 06-09-2011 |
20120309648 | INTEGRATED MICROFLUIDICS FOR HIGHLY PARALLEL SCREENING OF CHEMICAL REACTIONS - A microfluidic system has a microfluidic mixer and a sample storage component that is in fluid connection with the microfluidic mixer. The microfluidic mixer has a mixing section; a target molecule input section that is in fluid connection with the mixing section, the target molecule input section being suitable to provide a fluid into the mixing section that contains molecules to be targeted by chemical reactions; a first reagent input section that is in fluid connection with the mixing section, the first reagent input section being structured to selectively provide a first reagent selected from a plurality of reagents to test a chemical reaction with the target molecules; a second reagent input section that is in fluid connection with the mixing section, the second reagent input section being structured to selectively provide a second reagent selected from a plurality of reagents to test a chemical reaction with the target molecules and said first reagent; and a neutral fluid input section that is in selectable fluid connection with the sample storage component, the neutral fluid input section being structured to selectively provide a neutral fluid into the sample storage component between successive samples provided to the sample storage component to separate successive samples in a stratified arrangement. | 12-06-2012 |
John S. Wang, Los Angeles, CA US
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20120100403 | ELECTROLYTIC CELL AND METHOD OF ESTIMATING A STATE OF CHARGE THEREOF - A lithium ion battery includes a positive electrode, a negative electrode, and an electrolyte operatively disposed between the positive and negative electrodes. The negative electrode contains a composite material including graphitic carbon and a disordered carbon. | 04-26-2012 |
20120105068 | METHOD AND APPARATUS FOR ASSESSING BATTERY STATE OF HEALTH - A method for monitoring a lithium-ion battery cell includes monitoring a battery cell voltage and a corresponding state of charge of the battery cell during an electric power event which may include either an electric power charge event or an electric power discharge event. A measured potential-derivative is determined by differentiating the battery cell voltage in relation to the corresponding state of charge of the battery during the electric power event. The measured potential-derivative is compared with a preferred anode potential-derivative of an anode charge curve (for electric power discharge events) or an anode discharge curve (for electric power charge events), and with a preferred cathode potential-derivative of a cathode charge curve (for electric power charge events) or a cathode discharge charge curve (for electric power discharge events). A first state of health parameter of the battery cell corresponding to the comparison of the measured potential-derivative with the preferred anode potential-derivative of the anode curve is determined. And, a second state of health parameter of the battery cell corresponding to the comparison of the measured potential-derivative with the preferred cathode potential-derivative of the cathode curve is determined. | 05-03-2012 |
20120105069 | METHOD AND APPARATUS FOR ASSESSING BATTERY STATE OF HEALTH - A method for monitoring a lithium-ion battery cell includes monitoring a battery cell voltage and a corresponding charge capacity of the battery cell during an electric power event which may include either an electric power charge event or an electric power discharge event. A measured charge-capacity-derivative is determined by differentiating the charge capacity in relation to the corresponding battery cell voltage during the electric power event. The measured charge-capacity-derivative is compared with a preferred anode charge-capacity-derivative of an anode charge curve (for electric power discharge events) or an anode discharge curve (for electric power charge events), and with a preferred cathode charge-capacity-derivative of a cathode charge curve (for electric power charge events) or a cathode discharge charge curve (for electric power discharge events). A first state of health parameter of the battery cell corresponding to the comparison of the measured charge-capacity-derivative with the preferred anode charge-capacity-derivative of the anode curve is determined. And, a second state of health parameter of the battery cell corresponding to the comparison of the measured charge-capacity-derivative with the preferred cathode charge-capacity-derivative of the cathode curve is determined. | 05-03-2012 |
20120109503 | Li-ION BATTERY FOR VEHICLES WITH ENGINE START-STOP OPERATIONS - The operation of internal combustion, reciprocating engines in some automotive vehicles may be managed such that the engine operation is stopped each time the vehicle is brought to a stop, and then the engine is re-started when the operator presses the accelerator pedal to put the vehicle in motion. In some driving situations the engine of the vehicle may be stopped and re-started many times, which is a mode of engine operation for which the traditional 12 volt, lead-acid battery is not well suited. It is found that a six cell, lithium-ion battery combining LiFePO | 05-03-2012 |
20130071736 | PHASE SEPARATED SILICON-TIN COMPOSITE AS NEGATIVE ELECTRODE MATERIAL FOR LITHIUM-ION BATTERIES - A composite of silicon and tin is prepared as a negative electrode composition with increased lithium insertion capacity and durability for use with a metal current collector in cells of a lithium-ion battery. This electrode material is formed such that the silicon is present as a distinct amorphous phase in a matrix phase of crystalline tin. While the tin phase provides electron conductivity, both phases accommodate the insertion and extraction of lithium in the operation of the cell and both phases interact in minimizing mechanical damage to the material as the cell experiences repeated charge and discharge cycles. In general, roughly equal atomic proportions of the tin and silicon are used in forming the phase separated composite electrode material. | 03-21-2013 |
20140106220 | PHASE SEPARATED SILICON-TIN COMPOSITE AS NEGATIVE ELECTRODE MATERIAL FOR LITHIUM-ION AND LITHIUM SULFUR BATTERIES - A composite of silicon and tin is prepared as a negative electrode composition with increased lithium insertion capacity and durability for use with a metal current collector in cells of a lithium-ion battery or a lithium-sulfur battery. This negative electrode material is formed such that the silicon is present as a distinct amorphous phase in a matrix phase of crystalline tin. While the tin phase provides electron conductivity, both phases accommodate the insertion and extraction of lithium in the operation of the cell and both phases interact in minimizing mechanical damage to the material as the cell experiences repeated charge and discharge cycles. In general, roughly equal atomic proportions of the tin and silicon are used in forming the phase separated composite electrode material. | 04-17-2014 |
20140113197 | COATINGS FOR LITHIUM TITANATE TO SUPPRESS GAS GENERATION IN LITHIUM-ION BATTERIES AND METHODS FOR MAKING AND USE THEREOF - An electroactive material for use in an electrochemical cell, like a lithium-ion battery, is provided. The electroactive material comprises lithium titanate oxide (LTO) and has a surface coating with a thickness of less than or equal to about 30 nm that suppresses formation of gases within the electrochemical cell. Methods for making such materials and using such materials to suppress gas formation in electrochemical cells are likewise provided. | 04-24-2014 |
20150180023 | MULTIFUNCTIONAL HYBRID COATINGS FOR ELECTRODES MADE BY ATOMIC LAYER DEPOSITION TECHNIQUES - An electroactive material for use in an electrochemical cell, like a lithium ion battery, is provided. The electroactive material comprises a multifunctional hybrid protective coating system formed over an electroactive material. The coating system includes a first oxide-based coating disposed on one or more surfaces of the electroactive material, followed by a second coating deposited via a non-aqueous process. The second coating may be a fluoride-based, nitride-based, or carbide-based coating. The first and second coatings may be applied by atomic layer deposition (ALD) to form conformal ultrathin layers over the electroactive materials. Such a multifunctional hybrid protective coating system can suppress formation of gases within the electrochemical cell and also minimize formation of solid electrolyte interface (SEI) layers on the electrode to improve battery performance. Methods for making such materials and using such materials in electrochemical cells are likewise provided. | 06-25-2015 |
20150263379 | ELECTROCHEMICAL CELL FOR LITHIUM-BASED BATTERIES - An electrochemical cell is formed. The cell includes a non-lithium negative electrode in contact with a lithium ion permeable negative electrode current collector, and a positive electrode disposed in contact with a lithium ion permeable positive electrode current collector. The non-lithium negative electrode and the positive electrode are lithium ion permeable. The cell also has a lithium source electrode including lithium ions. A respective microporous polymer separator is disposed between the lithium source electrode and each of the negative and positive electrodes; or a first separator is disposed between the lithium source electrode and one of the negative and positive electrodes, and a second separator is disposed between the negative and positive electrodes. An electrolyte is introduced into the electrochemical cell. A voltage potential is applied across the electrochemical cell to pre-lithiate any of the non-lithium negative electrode and positive electrode with lithium ions from the lithium source electrode. | 09-17-2015 |
Jun Wang, Los Angeles, CA US
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20150117508 | Broadband amplifier linearization using captured histogram data - A transmitter's operation is characterized using components having relatively low cost and low complexity. A device includes comparator(s) that compare a transmitter's analog output to predetermined level(s) to generate count(s) associated with analog output range bin(s). Each of the predetermined levels is associated with a corresponding one of the analog output range bins. A transfer function of the transmitter is generated using the comparison count values associated with the analog output range bin(s). A histogram may be generated from the comparison count values associated with the various analog output range bins. An equalizer is implemented to process data that will be transmitted by the transmitter. The equalizer uses equalizer parameter(s) that are selected based on the characterization of the transmitter (e.g., its transfer function, its histogram, etc.). The equalizer may use default or start up parameters until the transmitter's operation is characterized. | 04-30-2015 |
Jun Ming Wang, Los Angeles, CA US
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20100105646 | ALLOPREGNANOLONE IN A METHOD FOR ENHANCING NEUROLOGICAL FUNCTION (ALZHEIMER DISEASE) - Neuro-enhancing agents, compositions and methods are disclosed herein. Preferred neuro-enhancing agents of the present invention include progesterone and metabolites of progesterone, such as 3α-hydroxy-5α-pregnan-20-one (THP). These agents yield neuro-enhancing effects on neural cells that include neural progenitor and/or stem cells, whereby the agents stimulate mitosis of neural progenitor cells, stimulate neurite growth and organization, protect against neural loss, or one or more of these neural processes. Thus, the neuro-enhancing agents, compositions and methods disclosed herein are useful to reverse or prevent neurological disease or defects associated with neural loss or degeneration, such as Alzheimer's disease, neurological injuries, including injuries resulting from radiation therapy, and age-related neurological decline, including impairments in memory and learning. | 04-29-2010 |
Lixin Wang, Los Angeles, CA US
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20080280819 | METHODS FOR PROMOTING HAIR GROWTH - This disclosure reveals that cyclic corticotrophin releasing factor (CRF) antagonist peptides (such as astressin B, its functional fragments, and their derivatives) induce hair growth and prevent hair loss in vivo. This important discovery enables, for instance, methods of promoting hair growth, and methods of treating hair loss (such as the hair loss that occurs normally in some individuals or that is the result of a health disorder or therapeutic treatment). Exemplary cyclic CRF antagonist peptides useful in the disclosed methods are provided throughout the disclosure. | 11-13-2008 |
Oliver Wang, Los Angeles, CA US
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20110109720 | STEREOSCOPIC EDITING FOR VIDEO PRODUCTION, POST-PRODUCTION AND DISPLAY ADAPTATION - Systems, methods and articles of manufacture are disclosed for stereoscopically editing video content. In one embodiment, image pairs of a sequence may be stereoscopically modified by altering at least one image of the image pair. The at least one image may be altered using at least one mapping function. The at least one image may also be altered based on a saliency of the image pair. The at least one image may also be altered based on disparities between the image pair. Advantageously, stereoscopic properties of video content may be edited more conveniently and efficiently. | 05-12-2011 |
Pin Wang, Los Angeles, CA US
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20140356414 | Targeted Crosslinked Multilamellar Liposomes - A liposome composition that is useful for treating a subject in need of cancer treatment includes a cross-linked multilamellar liposome having an exterior surface and an interior surface. The interior surface defines a central liposomal cavity. The multilamellar liposome includes at least a first lipid bilayer and a second lipid bilayer. The first lipid bilayer is covalently bonded to the second lipid bilayer. At least one anticancer compound is disposed within the multilamellar liposome. Methods for treating subjects are also provided. | 12-04-2014 |
Pu Wang, Los Angeles, CA US
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20140368817 | OPTICAL FIBER-BASED HYBRID SERS PLATFORM FOR IN VIVO DETECTION OF BIO-MOLECULES - An optical probe includes an optical fiber with a first end and a second end, and an enhanced surface on a portion of the first end of the optical fiber. The enhanced surface includes a patterned base layer including multiple protruding nano-pyramids, an intermediate layer over the patterned base layer, and a graphene layer over the intermediate layer. Using a layer of graphene to cover the enhanced surface increases the sensitivity of a surface-enhanced Raman spectroscopy (SERS) process performed in conjunction with the enhanced surface, and further increases the chemical stability and bio-compatibility of the enhanced surface. Further, placing the enhanced surface at the end of the optical fiber provides a self-contained probe for use with a SERS process, thereby allowing for in-vivo characterization of a sample. | 12-18-2014 |
Ruoxiang Wang, Los Angeles, CA US
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20110262354 | CYANINE-CONTAINING COMPOUNDS FOR CANCER IMAGING AND TREATMENT - This invention relates generally to cyanine-containing compounds; pharmaceutical compositions comprising cyanine-containing compounds; and methods of using cyanine-containing compounds for cancer cell imaging, cancer cell growth inhibition, and detecting cancer cells, for example. Compounds of the invention are preferentially taken up by cancer cells as compared to normal cells. This allows many uses in the cancer treatment, diagnosis, tracking and imaging fields. | 10-27-2011 |
20130101513 | METHOD OF USING NEAR INFRARED FLUORESCENT DYES FOR IMAGING AND TARGETING CANCERS - The present invention describes methods of identifying, detecting, imaging, isolating and locating cancer cells in a subject. The method invokes the use of near-infrared (NIR) organic carbocyanine dyes, particularly, near infrared heptamethine cyanine dyes and the detection of the fluorescence of these NIR dyes. The uptake of these dyes by cancer cells and not by normal cells, as well as their high intensity, among other things, allow for the detection of cancerous cells in a subject and facilitate their subsequent isolation. Further, detection of many tumor types and tumor cell populations under cell culture and in vivo conditions are described. | 04-25-2013 |
20130263297 | METHODS OF TREATING CANCER - The present invention relates to metastases. More specifically, the invention relates to compositions and methods for the inhibition of metastases of cancer cells, such as prostate cancer cells, to bones and soft tissue. The present invention also relates to the treatment of cancer, including but not limited to prostate cancer. Also provided are animal models for studying cancer metastasis; particularly, prostate cancer metastasis. Further provided are compositions, processes and systems to prognosticate cancer. | 10-03-2013 |
20150183736 | CYANINE-CONTAINING COMPOUNDS FOR CANCER IMAGING AND TREATMENT - This invention relates generally to cyanine-containing compounds; pharmaceutical compositions comprising cyanine-containing compounds; and methods of using cyanine-containing compounds for cancer cell imaging, cancer cell growth inhibition, and detecting cancer cells, for example. Compounds of the invention are preferentially taken up by cancer cells as compared to normal cells. This allows many uses in the cancer treatment, diagnosis, tracking and imaging fields. | 07-02-2015 |
20150335765 | CYANINE-CONTAINING COMPOUNDS FOR CANCER IMAGING AND TREATMENT - This invention relates generally to cyanine-containing compounds; pharmaceutical compositions comprising cyanine-containing compounds; and methods of using cyanine-containing compounds for cancer cell imaging, cancer cell growth inhibition, and detecting cancer cells, for example. Compounds of the invention are preferentially taken up by cancer cells as compared to normal cells. This allows many uses in the cancer treatment, diagnosis, tracking and imaging fields. | 11-26-2015 |
Shaocheng Wang, Los Angeles, CA US
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20140051485 | TECHNIQUES FOR MANAGING IDLE STATE ACTIVITY IN MOBILE DEVICES - An apparatus may comprise a radio-frequency (RF) transceiver and a message aggregation module arranged to intercept multiple messages from one or more mobile data applications during an idle mode of a device, one or more of the multiple messages operable to trigger a transition of the device from the idle mode to a connected mode by causing a radio resource control message to be sent from the device to a radio access network, the message aggregation module to store the multiple messages in a buffer associated with the one or more mobile data applications in order to maintain the device in the idle mode, and schedule for transmission by the RF transceiver the stored messages at a defined time instance based on a delay tolerance for the one or more mobile data applications when the device is in the connected mode. Other embodiments are disclosed and claimed. | 02-20-2014 |
20160081029 | TECHNIQUES FOR MANAGING IDLE STATE ACTIVITY IN MOBILE DEVICES - An apparatus may comprise a radio-frequency (RF) transceiver and a message aggregation module arranged to intercept multiple messages from one or more mobile data applications during an idle mode of a device, one or more of the multiple messages operable to trigger a transition of the device from the idle mode to a connected mode by causing a radio resource control message to be sent from the device to a radio access network, the message aggregation module to store the multiple messages in a buffer associated with the one or more mobile data applications in order to maintain the device in the idle mode, and schedule for transmission by the RF transceiver the stored messages at a defined time instance based on a delay tolerance for the one or more mobile data applications when the device is in the connected mode. Other embodiments are disclosed and claimed. | 03-17-2016 |
Shao-Cheng Wang, Los Angeles, CA US
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20110225626 | Reliable Reporting Of Location Data - A machine, such as a mobile device having telephony features, such as a voice over Internet Protocol (VoIP) telephony application, is configured with a secure environment in which a location provider within (more reliable) or external to (less reliable) the machine may determine location data for the machine and securely provide it to a telephony application program for incorporation into a call setup for calling a callee. The secure environment may be created through use of one or more of Intel's LaGrande Technology™ (LT), Vanderpool Technology (VT), or a Trusted Platform Module (TPM). The LT and VT allow defining secure independent components within the machine, such as by instantiating them as Virtual Machines, and the TPM allows components to cryptographically sign data, such as to facilitate ensuring the location data is not tampered with. A recipient of a telephone call setup including cryptographically secured location data may validate the location data and accept the call. Other embodiments may be described. | 09-15-2011 |
Shizhen Wang, Los Angeles, CA US
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20110191274 | Deep-Structured Conditional Random Fields for Sequential Labeling and Classification - Described is a technology by which a deep-structured (multiple layered) conditional random field model is trained and used for classification of sequential data. Sequential data is processed at each layer, from the lowest layer to a final (highest) layer, to output data in the form of conditional probabilities of classes given the sequential input data. Each higher layer inputs the conditional probability data and the sequential data jointly to output further probability data, and so forth, until the final layer which outputs the classification data. Also described is layer-by-layer training, supervised or unsupervised. Unsupervised training may process raw features to minimize average frame-level conditional entropy while maximizing state occupation entropy, or to minimize reconstruction error. Also described is a technique for back-propagation of error information of the final layer to iteratively fine tune the parameters of the lower layers, and joint training, including joint training via subgroups of layers. | 08-04-2011 |
Shutao Wang, Los Angeles, CA US
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20110305685 | SUPRAMOLECULAR APPROACH FOR PREPARATION OF SIZE CONTROLLABLE NANOPARTICLES - A supramolecular approach has been developed for preparation of size-controllable nanoparticles, from three different molecular building blocks. | 12-15-2011 |
20120003711 | DEVICE FOR CAPTURING CIRCULATING CELLS - The present invention provides devices and methods for capturing rare cells. The devices and methods described herein can be used to facilitate the diagnosis and monitoring of metastatic cancers. | 01-05-2012 |
Siyi Wang, Los Angeles, CA US
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20100065112 | Organic Photosensitive Devices Comprising a Squaraine Containing Organoheterojunction and Methods of Making Same - An organic photosensitive optoelectronic device comprising at least one Donor-Acceptor heterojunction formed from a squaraine compound of formula I: | 03-18-2010 |
20120248419 | ORGANIC PHOTOSENSITIVE DEVICES COMPRISING ARYL SQUARAINES AND METHODS OF MAKING THE SAME - There is disclosed squaraine compounds of formula I: | 10-04-2012 |
20130210189 | ENHANCED BULK HETEROJUNCTION DEVICES PREPARED BY THERMAL AND SOLVENT VAPOR ANNEALING PROCESSES - A method of preparing a bulk heterojunction organic photovoltaic cell through combinations of thermal and solvent vapor annealing are described. Bulk heterojunction films may prepared by known methods such as spin coating, and then exposed to one or more vaporized solvents and thermally annealed in an effort to enhance the crystalline nature of the photoactive materials. | 08-15-2013 |
Songlin Wang, Los Angeles, CA US
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20100196854 | Mesenchymal Stem Cell-Mediated Functional Tooth Regeneration - A method for reconstructing a functional tooth by using a carrier loaded with a plurality of mesenchymal stem cells including at least one of a stem cell derived from Apical Papilla (SCAP), Periodontal Ligament Stem Cells (PDLSC), and Dental Pulp Stem Cells (DPSC). The mesenchymal stem cell loaded carrier is planted into a site within a subject's oral cavity to form a bio-root upon which a crown may be affixed, The mesenchymal stem cells will develop new periodontal tissues to stabilize the bio-root. Methods disclosed herein are particularly beneficial for subjects lacking good bone structures for conventional crown treatments. | 08-05-2010 |
Taylor Gun-Jin Wang, Los Angeles, CA US
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20150374637 | SEMI-PERMEABLE CAPSULAR MEMBRANE WITH TAPERED CONDUITS FOR DIABETES FUNCTIONAL CURE - Some embodiments of the present disclosure include an encapsulated islet for treating diabetes. The encapsulated islet may include a semi-permeable capsular membrane having a plurality of layers including an outer immunoprotection layer, a bridging layer, and an inner backbone layer, each layer having a plurality of pores, wherein the pores increase in size from the immunoprotection layer to the backbone layer, creating the tapered conduits. The semi-permeable capsular membrane may include the following layers, in order from outermost layer to innermost layer: an immunoprotection layer, a bridging layer, and a backbone layer. With proper balancing of membrane thickness and tapered pore size distribution, the encapsulated islets may offer a diabetes treatment or functional cure without immunosuppressive drugs. | 12-31-2015 |
Wan Wang, Los Angeles, CA US
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20130196926 | CONTROLLED RELEASE OF OCULAR BIOPHARMACEUTICALS USING BIORESPONSIVE PROTEIN POLYMERS - Described herein are bioresponsive protein polymers for therapeutic applications, including delivery to physiologically demanding environments, such as the eye surface. Bioresponsive protein polymers can be fused with biopharmaceuticals using genetic engineering techniques for enhanced therapeutic activity. In certain embodiments, the unique temperature-sensitive phase separation properties of bioresponsive protein polymers, allows generation of therapeutics resistant to ocular clearance. Such fusion proteins containing bioresponsive protein polymers and biopharmaceuticals allow retention of drugs in the eye for much longer periods of time. Improved biostability and bioavailability improves drug efficacy, while reducing cost and eliminating the need for repeated drug application | 08-01-2013 |
Xiaolei Wang, Los Angeles, CA US
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20160111721 | VOLTAGE-RESPONSIVE COATING FOR LITHIUM-SULFUR BATTERY - A sulfur-containing electrode with a surface layer comprising voltage responsive material. The electrode is used in a lithium-sulfur or silicon-sulfur battery. | 04-21-2016 |
Yanju Wang, Los Angeles, CA US
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20120309648 | INTEGRATED MICROFLUIDICS FOR HIGHLY PARALLEL SCREENING OF CHEMICAL REACTIONS - A microfluidic system has a microfluidic mixer and a sample storage component that is in fluid connection with the microfluidic mixer. The microfluidic mixer has a mixing section; a target molecule input section that is in fluid connection with the mixing section, the target molecule input section being suitable to provide a fluid into the mixing section that contains molecules to be targeted by chemical reactions; a first reagent input section that is in fluid connection with the mixing section, the first reagent input section being structured to selectively provide a first reagent selected from a plurality of reagents to test a chemical reaction with the target molecules; a second reagent input section that is in fluid connection with the mixing section, the second reagent input section being structured to selectively provide a second reagent selected from a plurality of reagents to test a chemical reaction with the target molecules and said first reagent; and a neutral fluid input section that is in selectable fluid connection with the sample storage component, the neutral fluid input section being structured to selectively provide a neutral fluid into the sample storage component between successive samples provided to the sample storage component to separate successive samples in a stratified arrangement. | 12-06-2012 |
20130244257 | INTEGRATED MICROFLUIDIC RADIOASSAY AND IMAGING PLATFORM FOR SMALL SAMPLE ANALYSIS - An immunocapture-based in vitro kinase assay on an integrated polydimethylsiloxane (PDMS) microfluidics platform that can reproducibly measure kinase activity from as few as 3,000 cells is described. For this platform, the standard radiometric | 09-19-2013 |
Yanping Wang, Los Angeles, CA US
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20100196311 | METHODS AND COMPOSITIONS CONTAINING mTOR INHIBITORS FOR ENHANCING IMMUNE RESPONSES - Provided are compositions and methods for enhancing immune responses to an antigen. The compositions contain an isolated population of CD8+T cells and an inhibitor of mammalian target of rapamycin (mTOR). The method for obtaining an enhanced immune response to an antigen in an individual entails administering to the individual the antigen and an inhibitor of mammalian target of rapamycin (mTOR). CD8+T cells may also be used for adoptive cell transfer (ACT) therapy. | 08-05-2010 |
20110008887 | EPHA4-POSITIVE HUMAN ADULT PANCREATIC ENDOCRINE PROGENITOR CELLS - The invention relates to the discovery of a selective cell surface marker that permits the selection of a unique subset of pancreatic stem cells having a high propensity to differentiate into insulin-producing cells or into insulin-producing cell aggregates. | 01-13-2011 |
20130028898 | COMBINATION THERAPY WITH CD4 LYMPHOCYTE DEPLETION AND MTOR INHIBITORS - The invention provides methods for treating a malignant neoplastic cell proliferative disorder or disease, comprising administering to a subject in need thereof an effective amount of an mTOR inhibitor and an effective amount of a CD4 lymphocyte depleting agent. Such methods find utility in the treatment of certain subsets of malignant neoplastic cell proliferative disorders or diseases, e.g. renal cell carcinoma and melanoma. The invention also provides for pharmaceutical compositions comprising a therapeutically effective amount of an mTOR inhibitor and an effective amount of a CD4 lymphocyte depleting agent in a pharmaceutically acceptable carrier. | 01-31-2013 |
20150064180 | COMBINATION THERAPY WITH CD4 LYMPHOCYTE DEPLETION AND MTOR INHIBITORS - The invention provides methods for treating a malignant neoplastic cell proliferative disorder or disease, comprising administering to a subject in need thereof an effective amount of an mTOR inhibitor and an effective amount of a CD4 lymphocyte depleting agent. Such methods find utility in the treatment of certain subsets of malignant neoplastic cell proliferative disorders or diseases, e.g. renal cell carcinoma and melanoma. The invention also provides for pharmaceutical compositions comprising a therapeutically effective amount of an mTOR inhibitor and an effective amount of a CD4 lymphocyte depleting agent in a pharmaceutically acceptable carrier. | 03-05-2015 |
Yanzhi Wang, Los Angeles, CA US
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20130060392 | ENERGY PREDICTION SYSTEM - An energy management system includes a controller receiving electrical pricing information from an electrical utility company, measuring electrical power usage of a customer, and providing the electrical power usage to the electrical utility company. The controller is suitable to receive information regarding energy storage of a customer's electrical power storage and receive power information regarding a power generation source of the customer. The controller modifies the power usage of the energy management system based upon the pricing information, the electrical power usage, the energy storage, the power information, wherein the pricing information includes a plurality of temporal pricing levels and a temporal peak pricing level. | 03-07-2013 |
Yen-Nai Wang, Los Angeles, CA US
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20160033658 | SEMICONDUCTOR RADIATION DETECTOR ARRAY - A radiation detector with improved performance includes a probe and a first detector element constructed from planar semiconductor material in the probe. The detector further includes a second detector element constructed from planar semiconductor material in the probe. The detector further includes a focal point located outside of the probe. The detector further includes a circuit in communication with the detector elements. The first and second detector elements face the focal point and have the same solid angle relative to the focal point. The detector elements generate signals in response to incident radiation. The circuit receives the signals generated by the detector elements. | 02-04-2016 |
Yinglin Wang, Los Angeles, CA US
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20110045459 | Molecular determinants of EGFR kinase inhibitor response in glioblastoma - The invention disclosed herein provides methods for the examination and/or quantification of biochemical pathways that are disregulated in pathologies such as cancer and to reagents and kits adapted for performing such methods. | 02-24-2011 |
Yongzhe Wang, Los Angeles, CA US
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20120206451 | Method for Enhancing Depth Images of Scenes Using Trellis Structures - An image for a virtual view of a scene is generated based on a set of texture images and a corresponding set of depth images acquired of the scene. A set of candidate depths associated with each pixel of a selected image is determined. For each candidate depth, a cost that estimates a synthesis quality of the virtual image is determined. The candidate depth with a least cost is selected to produce an optimal depth for the pixel. Then, the virtual image is synthesized based on the optimal depth of each pixel and the texture images. The method also applies first and second depth enhancement before, and during view synthesis to correct errors or suppress noise due to the estimation or acquisition of the dense depth images and sparse depth features. | 08-16-2012 |
20150112897 | Method for Estimating Parameters of a Graph Spectral Filter Using Training Data - A method processes a signal represented as a graph by first determining a graph spectral transform based on the graph. In a spectral domain, parameters of a graph filter are estimated using a training data set of unenhanced and corresponding enhanced signals. The graph filter is derived based on the graph spectral transform and the estimated graph filter parameters. Then, the signal is processed using the graph filter to produce an output signal. The processing can enhance signals such as images b denoising or interpolating missing samples. | 04-23-2015 |
Z. Jane Wang, Los Angeles, CA US
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20160032330 | P-450-CATALYZED ENANTIOSELECTIVE CYCLOPROPANATION OF ELECTRON-DEFICIENT OLEFINS - The present invention pertains to the use of engineered variants of enzyme CYP102A, also known as P450-BM3, for cyclopropanation of olefins containing electron-withdrawing groups. One exemplary enzyme variant, referred to as BM3-HStar, contains five mutations away from wild-type P450-BM3, and demonstrates high activity towards cyclopropanation of olefinic substrates using ethyldiazoacetate (EDA) and other carbene transfer reagents. Products of these reactions are potential precursors of levomilnacipran derivatives, a class of compounds that have been shown to be selective inhibitors of monoamine transporters. In addition, cyclopropanation reactions with the P450-BM3 enzyme variants of the invention can be conducted in whole cells expressing the enzyme variants and can proceed under aerobic conditions. | 02-04-2016 |