Patent application number | Description | Published |
20120098742 | Hand-Held Orthopedic Electronic Interface Device and Method of Manufacture - An orthopedic cursor control device that supports a user's hand, or other controlling anatomy, in a functionally neutral posture. The device has a motion sensor housed in a base, a mound attached to the top of the base and an optional carpal support attached to the base. The surfaces of the base, mound and optional carpal support together support a user's hand, or other controlling anatomy, in the functionally neutral, or other appropriate, posture. The mound conforms to an interior portion of the user's hand when in a grasping configuration. An inner surface of the carpal support conforms to, and supports, the user's wrist in the functionally neutral posture. The carpal support extends beyond a distal end of the user's ulna bone when the user grasps the cursor control device. The functionally neutral posture has, at the distal end, the user's radial bone substantially vertically above their ulna bone. | 04-26-2012 |
20130285912 | Hand-held Orthopedic Electronic Interface Device and Method of Manufacture - An orthopedic cursor control device that supports a user's hand, or other controlling anatomy, in a functionally neutral posture. The device has a motion sensor housed in a base, a mound attached to the top of the base and an optional carpal support attached to the base. The surfaces of the base, mound and optional carpal support together support a user's hand, or other controlling anatomy, in the functionally neutral, or other appropriate, posture. The mound conforms to an interior portion of the user's hand when in a grasping configuration. An inner surface of the carpal support conforms to, and supports, the user's wrist in the functionally neutral posture. The carpal support extends beyond a distal end of the user's ulna bone when the user grasps the cursor control device. The functionally neutral posture has, at the distal end, the user's radial bone substantially vertically above their ulna bone. | 10-31-2013 |
Patent application number | Description | Published |
20130282828 | METHODS AND APPARATUS FOR INTEGRATING SOCIAL NETWORK METRICS AND REPUTATION DATA - A method for a computer system includes determining a first social distance for a first user with respect to a second user, determining a second social distance for a third user with respect to the second user, determining a first qualitative rating associated with the first user, determining a second qualitative rating associated with the second user, determining a first trust-metric for the first user in response to the first social distance and the first qualitative rating, determining a second trust-metric for the third user in response to the second social distance and the second qualitative rating, and prioritizing a first listing from the first user over a second listing from the third user for the second user, in response to the first trust-metric and the second trust-metric. | 10-24-2013 |
20150012419 | METHODS AND APPARATUS FOR TARGETING COMMUNICATIONS USING SOCIAL NETWORK METRICS - A method for a computer system includes receiving a first user communication, determining a first group of users, determining a target number of users, determining whether the first group of users includes the target number of users, and if not, providing the communication to the first group of users, determining a hierarchal mapping of groups of users in response to user memberships, determining a second group of users from the hierarchal mapping, determining a plurality of social network relationship factors for the second group of users with respect to the first user, and providing the communication to at least a subset of users in the second group of users in response to the first plurality of social network relationship factors. | 01-08-2015 |
20150012541 | METHODS AND APPARATUS FOR TARGETING COMMUNICATIONS USING SOCIAL NETWORK METRICS - A method for a computer system includes receiving a first user communication, determining a first group of users, determining a target number of users, determining whether the first group of users includes the target number of users, and if not, providing the communication to the first group of users, determining a hierarchal mapping of groups of users in response to user memberships, determining a second group of users from the hierarchal mapping, determining a plurality of social network relationship factors for the second group of users with respect to the first user, and providing the communication to at least a subset of users in the second group of users in response to the first plurality of social network relationship factors. | 01-08-2015 |
20150012605 | METHODS AND APPARATUS FOR TARGETING COMMUNICATIONS USING SOCIAL NETWORK METRICS - A method for a computer system includes receiving a first user communication, determining a first group of users, determining a target number of users, determining whether the first group of users includes the target number of users, and if not, providing the communication to the first group of users, determining a hierarchal mapping of groups of users in response to user memberships, determining a second group of users from the hierarchal mapping, determining a plurality of social network relationship factors for the second group of users with respect to the first user, and providing the communication to at least a subset of users in the second group of users in response to the first plurality of social network relationship factors. | 01-08-2015 |
20150012847 | METHODS AND APPARATUS FOR TARGETING COMMUNICATIONS USING SOCIAL NETWORK METRICS - A method for a computer system includes receiving a first user communication, determining a first group of users, determining a target number of users, determining whether the first group of users includes the target number of users, and if not, providing the communication to the first group of users, determining a hierarchal mapping of groups of users in response to user memberships, determining a second group of users from the hierarchal mapping, determining a plurality of social network relationship factors for the second group of users with respect to the first user, and providing the communication to at least a subset of users in the second group of users in response to the first plurality of social network relationship factors. | 01-08-2015 |
20150019542 | METHODS AND APPARATUS FOR TARGETING COMMUNICATIONS USING SOCIAL NETWORK METRICS - A method for a computer system includes receiving a first user communication, determining a first group of users, determining a target number of users, determining whether the first group of users includes the target number of users, and if not, providing the communication to the first group of users, determining a hierarchal mapping of groups of users in response to user memberships, determining a second group of users from the hierarchal mapping, determining a plurality of social network relationship factors for the second group of users with respect to the first user, and providing the communication to at least a subset of users in the second group of users in response to the first plurality of social network relationship factors. | 01-15-2015 |
20150019667 | METHODS AND APPARATUS FOR TARGETING COMMUNICATIONS USING SOCIAL NETWORK METRICS - A method for a computer system includes receiving a first user communication, determining a first group of users, determining a target number of users, determining whether the first group of users includes the target number of users, and if not, providing the communication to the first group of users, determining a hierarchal mapping of groups of users in response to user memberships, determining a second group of users from the hierarchal mapping, determining a plurality of social network relationship factors for the second group of users with respect to the first user, and providing the communication to at least a subset of users in the second group of users in response to the first plurality of social network relationship factors. | 01-15-2015 |
20150019668 | METHODS AND APPARATUS FOR TARGETING COMMUNICATIONS USING SOCIAL NETWORK METRICS - A method for a computer system includes receiving a first user communication, determining a first group of users, determining a target number of users, determining whether the first group of users includes the target number of users, and if not, providing the communication to the first group of users, determining a hierarchal mapping of groups of users in response to user memberships, determining a second group of users from the hierarchal mapping, determining a plurality of social network relationship factors for the second group of users with respect to the first user, and providing the communication to at least a subset of users in the second group of users in response to the first plurality of social network relationship factors. | 01-15-2015 |
Patent application number | Description | Published |
20100227675 | Virtual Playing Chips in a Multiuser Online Game Network - In various embodiments, virtual currency is used within a multiplayer online game in a restricted manner. | 09-09-2010 |
20120015715 | VIRTUAL PLAYING CHIPS IN A MULTIUSER ONLINE GAME NETWORK - Methods, systems, and computer programs are presented for executing game transactions in an online game to acquire virtual currency. One method includes an operation for detecting a request from a player to purchase virtual currency for use in the online game. Cash or credit is received, in an online transaction, to make the purchase of the virtual currency. The virtual currency of the online game is not redeemable for cash or credit so the virtual currency cannot be considered gambling proceeds. The method further includes an operation for crediting the player with an amount of virtual currency based on the amount of the received cash or credit. | 01-19-2012 |
20120015724 | EMBEDDING OF GAMES INTO THIRD PARTY WEBSITES - Systems and methods for embedding and tracking revenue from fully operational games into third party websites are disclosed. | 01-19-2012 |
20120015725 | EMBEDDING OF GAMES INTO THIRD PARTY WEBSITES - Systems and methods for embedding and tracking revenue from fully operational games into third party websites are disclosed. | 01-19-2012 |
20120015747 | EMBEDDING OF GAMES INTO THIRD PARTY WEBSITES - Systems and methods for embedding and tracking revenue from fully operational games into third party websites are disclosed. | 01-19-2012 |
20150072780 | EMBEDDING OF GAMES INTO THIRD PARTY WEBSITES - Systems and methods for embedding and tracking revenue from fully operational games into third party websites are disclosed. | 03-12-2015 |
Patent application number | Description | Published |
20100144636 | PEPTIDES DERIVED FROM RAS-P21 AND USES THEREFOR - A method of treating ras-transformed and ras-related cancer, including: administering to a plurality cells, including ras-transformed cancer cells and normal cells, a peptide material having a membrane resident peptide and a ras-p21 component, the membrane resident peptide attached to the carboxyl or amino terminal end of the ras-p21 component. | 06-10-2010 |
20110183915 | Small Molecule Cancer Treatments that cause Necrosis in Cancer Cells but do not Affect Normal Cells - A method of treating cancer in a subject, including: providing a subject having a plurality of cancer cells; and administering to the subject, a therapeutically effective amount of a composition including: an HDM-2 binding component; and a membrane resident component, the membrane resident component bound to the HDM-2 binding component. Also provided are a method of selectively necrosing cancer cells, a method of causing membranolysis in cancer cells, and a cancer treatment composition. | 07-28-2011 |
20120177566 | MEMBRANE RESIDENT PEPTIDE IN ANTI-CANCER PEPTIDES CAUSES TUMOR CELL NECROSIS RATHER THAN APOPTOSIS OF CANCER CELLS - An aspect of the invention provides a method of selectively necrosing cells, comprising: providing a plurality cells, including at least one cancer cell and at least one non-cancerous cell; and administering to the cells a compound, including an HDM-2 targeting component and a cytotoxic component attached to the HDM-2 targeting component, wherein said compound comprises a membrane-active form. | 07-12-2012 |
20140371156 | MEMBRANE RESIDENT PEPTIDE IN ANTI-CANCER PEPTIDES CAUSES TUMOR CELL NECROSIS RATHER THAN APOPTOSIS OF CANCER CELLS - An aspect of the invention provides a method of selectively necrosing cells, comprising: providing a plurality cells, including at least one cancer cell and at least one non-cancerous cell; and administering to the cells a compound, including an HDM-2 targeting component and a cytotoxic component attached to the HDM-2 targeting component, wherein said compound comprises a membrane-active form. | 12-18-2014 |
Patent application number | Description | Published |
20100184970 | Porphyrin-based compounds for tumor imaging and photodynamic therapy - This invention describes a first report on the synthesis of certain | 07-22-2010 |
20110223102 | MULTIMODALITY AGENTS FOR TUMOR IMAGING AND THERAPY - A compound that is a conjugate of an antagonist to an integrin expressed by a tumor cell and at least one of a tumor avid tetrapyrollic photosensitizer, a fluorescent dye, and a radioisotope labeled moiety wherein the radioisotope is | 09-15-2011 |
20110264027 | B RING REDUCED-D RING OXIDIZED TETRAPYROLLIC PHOTOSENSITIZERS FOR PHOTODYNAMIC THERAPY AND TUMOR IMAGING - Tetrapyrollic photosensitizers and imaging agent compounds having A, B, C, and D rings and having a reduced B ring and an oxidized D ring. The compounds preferably have a purity of at least 95 percent and preferably have a fused system connected at an unsaturated carbon atom of the C ring nearest the D ring and at the unsaturated carbon atom between the C and D rings. The invention also includes a method of making the compounds at over 95 percent yield by starting with a B and D ring oxidized tetrapyrollic compound and dissolving it in a halogenated hydrocarbon solvent and treating it with sufficient nitroalkane solution of FeCl | 10-27-2011 |
20110288234 | SILICA NANOPARTICLES POSTLOADED WITH PHOTOSENSITIZERS FOR DRUG DELIVERY IN PHOTODYNAMIC THERAPY - A nanoparticle including a polysiloxane base having an exterior surface and having a photosensitizer at least partly exposed at its exterior surface, said photosensitizer being secured to the exterior surface by loading the photosensitizer onto the surface after formation of the polysiloxane base of the nanoparticle. The nanoparticle may have tumor targeting moieties and may be post loaded with cyanine dye. The nanoparticle preferably includes post loaded moieties providing at least two of tumor specificity, photodynamic properties and imaging capabilities and the photosensitizer is tagged with a radioisotope. A method for preparation of the nanoparticle is also provided. | 11-24-2011 |