Rybicki
Chris Rybicki, Fall River, MA US
Patent application number | Description | Published |
---|---|---|
20110282402 | INSTRUMENTS AND METHODS FOR MANIPULATING VERTEBRA - A method for manipulating a vertebra includes connecting a first bone anchor to a first vertebra, connecting a second bone anchor to a second bone anchor, positioning a spinal rod in a receiving member of the first bone anchor and in a receiving member of the second bone anchor, connecting a first instrument to the receiving member of the first bone anchor, and manipulating the first instrument to rotate first bone anchor and the first vertebra relative to the second vertebra. | 11-17-2011 |
20140188182 | INSTRUMENTS AND METHODS FOR MANIPULATING VERTEBRA - A method for manipulating a vertebra includes connecting a first bone anchor to a first vertebra, connecting a second bone anchor to a second bone anchor, positioning a spinal rod in a receiving member of the first bone anchor and in a receiving member of the second bone anchor, connecting a first instrument to the receiving member of the first bone anchor, and manipulating the first instrument to rotate first bone anchor and the first vertebra relative to the second vertebra. | 07-03-2014 |
Christopher Ryan Rybicki, Charlotte, NC US
Patent application number | Description | Published |
---|---|---|
20110034962 | Spinal Rod Approximator - Spinal rod approximator for seating a stabilizing rod in a rod-receiving portion of a spinal implant and inserting closure mechanism is provided. In one embodiment, a spinal rod approximator is provided including a body with gripping branches, inserter shaft, threaded collar, and outer sleeve. | 02-10-2011 |
Edward Peter Rybicki, Pinelands ZA
Patent application number | Description | Published |
---|---|---|
20110262478 | Recombinant Protein Bodies as Immunogen-Specific Adjuvants - An immunogen-specific is adjuvant for a vaccine or inoculum is disclosed. The adjuvant is comprised of particulate recombinant protein body-like assemblies (RPBLAs) that contain a recombinant fusion protein that contains two portions peptide-linked together. A first portion is a protein body-inducing sequence (PBIS) and a second portion is a T-cell stimulating immunogenic polypeptide whose sequence is that of a pathogenic polypeptide sequence present in or induced by a vaccine or inoculum. The adjuvant, when used as an inoculum in a host animal without a prior priming vaccination or inoculation, does not induce production of antibodies or T cell activation to the pathogenic sequence. | 10-27-2011 |
Edward Peter Rybicki, Cape Town ZA
Patent application number | Description | Published |
---|---|---|
20090047302 | Chimaeric Human Papillomavirus 16 L1 Virus Like Particles and a Method for Preparing the Particles - A method for producing a chimaeric human papillomavirus (HPV) L1 polypeptide containing a heterologous peptide, and in particular, a HPV L2 peptide comprising the steps of introducing a DNA sequence coding for the heterologous peptide into a DNA sequence coding for the L1 polypeptide; introducing the DNA sequence including the sequences for the L1 polypeptide and heterologous peptide into a host cell in which the DNA sequence can be expressed; causing expression of the DNA sequence; and recovering the resulting chimaeric L1 polypeptide which includes the heterologous peptide. The invention also describes a vector for use in the method, a host cell containing the vector, and a vaccine including the chimaeric HPV L1 polypeptide produced according to the method. | 02-19-2009 |
20090220543 | Expression of Proteins in Plants - The invention relates to a method of producing a HPV polypeptides and/or an influenza virus H5 polypeptide in a plant comprising the steps of cloning a HPV gene; and/or an influenza virus H5 gene or nucleic acid encoding their functional equivalents into a vector adapted to target components present in the plant, infiltrating at least a portion of the plant with the vector or transforming plant tissue with the vector so as to transiently express the HPV polypeptides and/or an influenza virus H5 polypeptide, and/or to create a transgenic plant; and recovering the HPV polypeptides and/or an influenza virus H5 polypeptide expressed by the plant. The invention further relates to vectors, transgenic plants or parts thereof and the progeny of such plants used in or which come about as a result of the method. | 09-03-2009 |
20090285852 | Expression System Incorporating a Capsid Promotor Sequence as an Enhancer of a Cytomegalovirus Promotor - The invention provides a method for enhancing expression of a transgene in a host cell, which includes the steps of inserting a capsid promoter element (Pcap), or a sequence comprising the reverse complement of the capsid promoter element (PcapR), into a mammalian expression cassette upstream (5′) of a cytomegalovirus immediate/early enhancer/promoter region (Pcmv); inserting the transgene into the expression cassette downstream (3′) of the cytomegalovirus immediate/early enhancer/promoter region; inserting a vector containing the expression cassette into the host organism; and causing expression of the transgene. The capsid promoter element (Pcap) is typically from a circovirus, parvovirus or anellovirus. The transgene is typically expressed at a higher level than when expressed by a vector containing the expression cassette without the transcriptional control element. An expression cassette, vector, DNA vaccine, pharmaceutical composition and method of treatment are also claimed. | 11-19-2009 |
20130130314 | Expression of Proteins in Plants - The invention relates to a method of producing an influenza virus H5 polypeptide in a plant comprising the steps of cloning an influenza H5 gene or nucleic acid encoding its functional equivalent into a vector adapted to target components present in the plant, infiltrating at least a portion of the plant with the vector or transforming plant tissue with the vector so as to transiently express the influenza virus H5 polypeptide, and/or to create a transgenic plant; and recover the influenza virus H5 polypeptide expressed by the plant. The invention further relates to vectors, transgenic plants or parts thereof and the progeny of such plants used in or which come about as a result of the method. | 05-23-2013 |
20140377367 | HPV Chimaeric Particle - This invention relates to a chimaeric human papillomavirus (HPV) virus like particle (VLP) having a diameter of about 30 nm. The invention further relates to methods of treatment and/or prophylaxis of HPV infection and/or cervical cancer by administration of the chimaeric HPV VLP of the invention to a subject. | 12-25-2014 |
20150216961 | ROTAVIRUS-LIKE PARTICLE PRODUCTION IN PLANTS - A method of producing a virus-like particle (VLP) in a plant is provided. The method comprises introducing a first nucleic acid into the plant, or portion of the plant. The first nucleic acid comprising a first regulatory region active in the plant operatively linked to a nucleotide sequence encoding one or more rotavirus structural protein for example but not limited to rotavirus protein VP2. The nucleotide sequence may further comprise one or more than one amplification element and/or a compartment targeting sequence. A second nucleic acid might be introduced into the plant, or portion of the plant. The second nucleic acid comprises a second regulatory region active in the plant and operatively linked to a nucleotide sequence encoding one or more rotavirus structural protein, for example but not limited to rotavirus protein VP6. Optionally, a third nucleic acid and/or fourth nucleic acid might be introduced into the plant, or portion of the plant. The third nucleic acid comprises a third regulatory region active in the plant and operatively linked to a nucleotide sequence encoding one or more rotavirus structural protein, for example but not limited to rotavirus protein VP4. The fourth nucleic acid comprises a fourth regulatory region active in the plant and operatively linked to a nucleotide sequence encoding one or more rotavirus structural protein, for example but not limited to rotavirus protein VP7. The plant or portion of the plant is incubated under conditions that permit the expression of the nucleic acids, thereby producing the VLP. | 08-06-2015 |
Frank Rybicki, Sudbury, MA US
Patent application number | Description | Published |
---|---|---|
20120251443 | IMPLANTABLE CONTRAST AGENTS AND METHODS - The present disclosure provides compositions and methods based on implantable contrast agents that are useful for imaging tissue and organs. | 10-04-2012 |
Frank J. Rybicki, Sudbury, MA US
Patent application number | Description | Published |
---|---|---|
20100305424 | K-SPACE SAMPLE DENSITY COMPENSATION FOR MAGNETIC RESONANCE IMAGE RECONSTRUCTION - The present invention provides a method for producing density-compensated MR images having improved signal-to-noise ratio and with reduced computational burden. The method includes sampling MR data using a rotationally symmetric acquisition trajectory, generating a cross-correlation matrix, and applying a discreet Fourier transform (DFT) to the acquired MR data and the cross correlation matrix. The method further includes employing the transformed MR data and transformed cross-correlation matrix in a linear system to produce a set of density-compensated transformed MR data, which may transformed into density compensated MR data by application of an inverse DFT. The density compensated MR data may be reconstructed by a variety of techniques to produce density compensated images. | 12-02-2010 |
Karol Rybicki, Piekary Slaskie PL
Patent application number | Description | Published |
---|---|---|
20130295305 | ELASTIC LONGITUDINAL NET OF A CLOSED PERIPHERY, IN PARTICULAR FOR WRAPPING UP SAUSAGE AND FOOD PRODUCTS - An elastic longitudinal net ( | 11-07-2013 |
Mathew A. Rybicki, Leander, TX US
Patent application number | Description | Published |
---|---|---|
20140184080 | LIGHT EMITTING DIODE LIGHT STRUCTURES - A Light Emitting Diode (LED) light includes a bridge rectifier configured to be powered by an alternating current power source and to produce a rectified output. Control circuitry couples to the bridge rectifier and is configured to produce a shunt signal when the rectified output is less than a threshold voltage. A series connected Light Emitting Diode (LED) string includes a first group of LEDs and a second group of LEDs. A switch couples to a first side of the second group of LEDs and is controlled by the shunt signal to deactivate the second group of LEDs. The control circuitry may include a ratio metric series resistor string configured to sense a proportion of the rectified output and an inverter configured to generate the shunt signal based on the proportion of the rectified output. | 07-03-2014 |
Mathew A. Rybicki, Austin, TX US
Patent application number | Description | Published |
---|---|---|
20090022240 | Low power distributed transmitter - A low power distributed transmitter includes a signal generator, signal partitioning module, signal processing module, a plurality of amplifiers, and a transmitting module. The signal generator is operably coupled to generate a signal to represent base-band data in accordance with a particular transmission protocol. The signal partitioning module is operably coupled to partition the signal into a plurality of signal partitions based on a peak-to-average ratio of the signal. The signal processing module processes the plurality of signal partitions to in accordance with the particular transmission protocol to produce processed signals. Each of the amplifiers amplifies a corresponding one of the processed signal partitions to produce amplified signal partitioned. The transmitting module transmits, via an antenna or a plurality of antennas, the amplified signal partitions as a composite amplified signal. | 01-22-2009 |
20090034660 | LOW POWER RADIO TRANSMITTER USING PULSE TRANSMISSIONS - A radio receiver includes a low-noise amplifier, pulse-to-signal conversion module, and intermediate frequency stage. The low-noise amplifier is operably coupled to receive and amplify an M-bit signal at a radio frequency. The M-bit signal at a radio frequency is representative of a pulse signal that is carried on a radio frequency. The pulse-to-signal conversion module demodulates the M-bit signal to produce an N-bit signal at an intermediate frequency. For example, the pulse-to-signal conversion module performs pulse-width demodulation, pulse-density demodulation, or pulse-position demodulation to recapture the N-bit signal. The intermediate frequency stage steps down the frequency of the N-bit signal to produce a base-band digital signal. | 02-05-2009 |
Paul N. Rybicki, San Francisco, CA US
Patent application number | Description | Published |
---|---|---|
20110239149 | TIMELINE CONTROL - Timeline control techniques are described. In one or more implementations, a timeline is displayed that is divided into a plurality of intervals, each of which corresponds to a respective period of time. Responsive to selection of one of the plurality of intervals, a control is displayed within the selected interval that is scrollable within an area defined by the selected interval to move between content that is associated at corresponding points in time at a scrolling speed that is based at least in part on an amount of the content that is associated with the interval. | 09-29-2011 |
Robert G. Rybicki, Pittsburg, PA US
Patent application number | Description | Published |
---|---|---|
20080308100 | System and method for determining humidity in a respiratory treatment system - A patient treatment system and method comprising a patient circuit, a pressurizing flow module disposed in the patient circuit, a humidifier disposed in the patient circuit, a monitor, sensors within the patient circuit, and a processor. The patient circuit delivers a flow of gas from a gas source to an airway of a patient. The pressurizing flow module elevates the pressure of the gas within the patient circuit. The humidifier elevates the humidity of the gas in the patient circuit to a circuit humidity level. The monitor monitors at least one parameter of the gas from the gas source. The sensors generate corresponding signals that can be processed to estimate a rate at which vapor is added to the gas in the patient circuit. The processor determines the humidity level of the gas in the patient circuit downstream from the humidifier based on the signals generated by the sensors and the at least one parameter of the gas in the gas source. | 12-18-2008 |
Robert Gerard Rybicki, Pitsburgh, PA US
Patent application number | Description | Published |
---|---|---|
20150343167 | SUBJECT INTERFACE APPLIANCE HEATING SYSTEM - Systems and methods for heating a flow of breathable gas during delivery to a subject use a subject interface appliance ( | 12-03-2015 |
Stephen G. Rybicki, Boxborough, MA US
Patent application number | Description | Published |
---|---|---|
20140344508 | MANAGING MEMORY AND STORAGE SPACE FOR A DATA OPERATION - Processing a plurality of data units to generate result information, includes: performing a data operation for each data unit of a first subset of data units from the plurality of data units, and storing information associated with a result of the data operation in a first set of one or more data structures stored in working memory space of a memory device; after an overflow condition on the working memory space is satisfied, storing information in overflow storage space of a storage device; and repeating an overflow processing procedure multiple times during the processing of the plurality of data units, the overflow processing procedure including: updating a new set of one or more data structures stored in the working memory space using at least some information stored in the overflow storage space. | 11-20-2014 |