Presta
Alessandro Presta, San Francisco, CA US
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20150095348 | SYSTEMS AND METHODS FOR DYNAMIC MAPPING FOR LOCALITY AND BALANCE - To dynamically map nodes for locality and balance, computer implemented methods, systems, and computer readable media, in an embodiment, may compute histograms for nodes in a first partition. Histograms may be computed for nodes in a second partition. The second partition may be selected as a candidate partition for a set of nodes in the first partition based on the histograms for the nodes in the first partition. The first partition may be selected as a candidate partition for a set of nodes in the second partition based on the histograms for the nodes in the second partition. At least a portion of the set of nodes in the first partition may be mapped to the second partition and at least a portion of the set of nodes in the second partition may be mapped to the first partition based on load balancing. | 04-02-2015 |
20150100574 | SYSTEMS AND METHODS FOR MAPPING AND ROUTING BASED ON CLUSTERING - Classifications associated with a plurality of nodes may be identified. The classifications may be grouped into first level communities based on edge weights between the classifications. The first level communities may be grouped into second level communities based on edge weights between the first level communities. A sorted list of the plurality of nodes may be generated based on the classifications, the first level communities, and the second level communities. Unique identifiers (IDs) may be assigned sequentially to the sorted list of the plurality of nodes. | 04-09-2015 |
20150100661 | SYSTEMS AND METHODS FOR MAPPING AND ROUTING BASED ON CLUSTERING - Unique identifiers (IDs) associated with a plurality of nodes may be provided. Nodes clustered within a community may be assigned numerically proximate unique IDs. A number of partitions associated with a plurality of machines may be determined. The unique IDs may be segmented into divisions based on the number of partitions. The unique IDs may be mapped to the plurality of machines based on the divisions. | 04-09-2015 |
Anthony Presta, Hamilton CA
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20090170199 | SEPARATION AND SORTING OF DIFFERENT BIOLOGICAL OBJECTS - The present invention relates to a method for the separation of biological objects in a solution which have different viscoelastic properties, wherein said method comprises a filtration step allowing the higher viscoelastic biological objects to pass through the membrane while retaining the lower viscoelastic biological objects above the membrane, and a recovery step wherein the separated lower viscoelastic biological objects are recovered above or onto the membrane and/or the separated higher viscoelastic biological objects are recovered in the filtrate. Advantageously, the biological objects are cells. More advantageously, the recovered cells are viable cells. In one preferred embodiment, the cells are tumor cells. In another preferred embodiment, the cells are fetal cells and the method finds an application in prenatal diagnosis. | 07-02-2009 |
20100248207 | SEPARATION METHOD OF BIOLOGICAL OBJECTS RELATIVE TO THEIR VISCOELASTIC PROPERTIES - The present invention relates to a method for the separation of biological objects in a solution which have different viscoelastic properties, wherein said method comprises a filtration step allowing the higher viscoelastic biological objects to pass through the membrane while retaining the lower viscoelastic biological objects above the membrane, and a recovery step wherein the separated lower viscoelastic biological objects are recovered above or onto the membrane and/or the separated higher viscoelastic biological objects are recovered in the filtrate. Advantageously, the biological objects are cells. More advantageously, the recovered cells are viable cells. In one preferred embodiment, the cells are tumor cells. In another preferred embodiment, the cells are fetal cells and the method finds an application in prenatal diagnosis. | 09-30-2010 |
Kylie Presta, Missoula, MT US
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20140312262 | CORROSION INHIBITING, FREEZING POINT LOWERING COMPOSITIONS - The present invention relates to corrosion inhibiting, freeze point lowering compositions comprising a mixture of a freeze point lowering agent and a corrosion inhibiting compound. The corrosion inhibiting, freeze point lowering compositions can be used in deicing brines or deicing solutions. | 10-23-2014 |
Leonard Presta, South San Francisco, CA US
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20120201813 | POLYPEPTIDE VARIANTS WITH ALTERED EFFECTOR FUNCTION - The present invention concerns polypeptides comprising a variant Fc region. More particularly, the present invention concerns Fc region-containing polypeptides that have altered effector function as a consequence of one or more amino acid modifications in the Fc region thereof. | 08-09-2012 |
20120202224 | POLYPEPTIDE VARIANTS WITH ALTERED EFFECTOR FUNCTION - The present invention concerns polypeptides comprising a variant Fc region. More particularly, the present invention concerns Fc region-containing polypeptides that have altered effector function as a consequence of one or more amino acid modifications in the Fc region thereof. | 08-09-2012 |
Leonard G. Presta, Palo Alto, CA US
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20110142853 | Engineered Anti-IL-23p19 Antibodies - Engineered antibodies to human IL-23p19 are provided, as well as uses thereof, e.g. in treatment of inflammatory, autoimmune, and proliferative disorders. | 06-16-2011 |
20110158992 | Engineered Anti-IL-23R Antibodies - Antibodies to human IL-23R are provided, as well as uses thereof, e.g. in treatment of inflammatory, autoimmune, and proliferative disorders. | 06-30-2011 |
20130122009 | Engineered Anti-IL-23p19 Antibodies - Engineered antibodies to human IL-23p19 are provided, as well as uses thereof, e.g. in treatment of inflammatory, autoimmune, and proliferative disorders. | 05-16-2013 |
Leonard G. Presta, South San Francisco, CA US
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20110206663 | Anti-Interferon-Alpha Antibodies - The present invention relates generally to the generation and characterization of neutralizing anti-IFN-α monoclonal antibodies with broad reactivity against various IFN-α subtypes. The invention further relates to the use of such anti-IFN-α antibodies in the diagnosis and treatment of disorders associated with increased expression of IFN-α, in particular, autoimmune disorders such as insulin-dependent diabetes mellitus (IDDM) and systemic lupus erythematosus (SLE). | 08-25-2011 |
20130084295 | ANTI-INTERFERON-ALPHA ANTIBODIES - The present invention relates generally to the generation and characterization of neutralizing anti-IFN-α monoclonal antibodies with broad reactivity against various IFN-α subtypes. The invention further relates to the use of such anti-IFN-α antibodies in the diagnosis and treatment of disorders associated with increased expression of IFN-α, in particular, autoimmune disorders such as insulin-dependent diabetes mellitus (IDDM) and systemic lupus erythematosus (SLE). | 04-04-2013 |
20130309236 | ANTI-INTERFERON-ALPHA ANTIBODIES - The present invention relates generally to the generation and characterization of neutralizing anti-IFN-α monoclonal antibodies with broad reactivity against various IFN-α subtypes. The invention further relates to the use of such anti-IFN-α antibodies in the diagnosis and treatment of disorders associated with increased expression of TUN-α, in particular, autoimmune disorders such as insulin-dependent diabetes mellitus (IDDM) and systemic lupus erythematosus (SLE). | 11-21-2013 |
Leonard G. Presta, San Francisco CA
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20150023951 | ANTI-VEGF ANTIBODIES - Humanized and variant anti-VEGF antibodies and various uses therefor are disclosed. The anti-VEGF antibodies have strong binding affinities for VEGF; inhibit VEGF-induced proliferation of endothelial cells in vitro; and inhibit tumor growth in vivo. | 01-22-2015 |
Marco Presta, Brescia IT
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20090215689 | FGF2-BINDING PEPTIDES AND USES THEREOF - FGF2-binding peptides are here described, which have been designed starting from the N-terminal region of PTX3, in particular spanning the PTX3(82-110) region. Synthetic peptides related to this sequence are able to bind FGF2 and to inhibit its pro-angiogenic activity in vitro and in vivo with no anticipated impact on innate immunity. | 08-27-2009 |
Massimiliano Presta, Roma IT
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20100325840 | SELECTIVE COMPLIANCE HINGE - A selective compliance hinge, apt to define a turning pair with a default axis of rotation (A), allows to obtain a selective compliance turning pair, hence with the advantages typical of such applications but providing the best precision and movement repeatability, and comprises a connecting element ( | 12-30-2010 |
Massimillano Presta, Roma IT
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20110028988 | SELECTIVE COMPLIANCE WIRE ACTUATED MOBILE PLATFORM, PARTICULARLY FOR ENDOSCOPIC SURGICAL DEVICES - A wire-operated selective compliance mobile platform ( | 02-03-2011 |
Matt Presta, San Mateo, CA US
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20150191296 | System and Method for Protective Eyewear Dispensing - A system and method for improved dispensing for protective eyewear components, including frames, lenses and assembled protective eyewear glasses, is described. A housing stores and dispenses the eyewear components through an opening. In an embodiment, the eyewear components may be detachably connected together, such as via perforations, and/or may be coiled in a roll or stacked in serpentine configuration within the housing. Also, in one embodiment, a lever or other mechanism may be coupled to the housing to provide advantageous operations of the dispenser, including assembling and/or dispensing the eyewear components. Accordingly, the system and method provides advantages in that rapid and hygienic dispensing of protective eyewear components may be provided. | 07-09-2015 |
Matthew Presta, San Mateo, CA US
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20090018538 | SYSTEMS AND METHODS FOR DELIVERING ENERGY TO PASSAGEWAYS IN A PATIENT - Systems and methods for delivering energy to passageways in a patient, such as airways in the lung of a patient for treating asthma. One embodiment of a method for delivering energy to a passageway comprises positioning an access device in a lung airway of a patient and advancing an elongated body of a treatment device along the access device until an energy delivery unit at a distal portion of the elongated body projects from the access device. The method can further include expanding the energy delivery unit such that energy delivery elements contact a sidewall of the airway and activating an energy supply coupled to the treatment device such that energy is delivered to the sidewall of the airway. A single person physically operates both the access device and the treatment device while expanding the energy delivery unit and activating the energy supply. | 01-15-2009 |
20120330299 | SYSTEMS AND METHODS FOR DELIVERING ENERGY TO PASSAGEWAYS IN A PATIENT - Systems and methods for delivering energy to passageways in a patient, such as airways in the lung of a patient for treating asthma. One embodiment of a method for delivering energy to a passageway comprises positioning an access device in a lung airway of a patient and advancing an elongated body of a treatment device along the access device until an energy delivery unit at a distal portion of the elongated body projects from the access device. The method can further include expanding the energy delivery unit such that energy delivery elements contact a sidewall of the airway and activating an energy supply coupled to the treatment device such that energy is delivered to the sidewall of the airway. A single person physically operates both the access device and the treatment device while expanding the energy delivery unit and activating the energy supply. | 12-27-2012 |
Matthew P. Presta, San Mateo, CA US
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20140039382 | Analyte Meter Module for Medication Delivery Device - Presented herein is a modular analyte measurement system. The analyte measurement system includes an analyte meter and at least one modular attachment. In one embodiment, a modular attachment is provided to communicate with, and transmit/receive data from, one or more medication delivery device. Embodiments of the present invention relate to modular components of the analyte measurement system. | 02-06-2014 |
20140051958 | Analyte Meter Communication Module - Presented herein is a modular analyte measurement system. The analyte measurement system includes an analyte meter and at least one modular attachment. In one embodiment, a modular attachment is provided to communicate with, and transmit/receive data to, one or more external devices. Embodiments of the present invention relate to modular components of the analyte measurement system. | 02-20-2014 |