Maria Dolores
Maria Dolores Baeza Alvarado, Lerma MX
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20080200601 | Reactive block copolymers for the preparation of inorganic tubule-polymer composites - A method for modifying an inorganic tubule, such as halloysite, cylindrite, boulangerite, or imogolite, with a functionalized block copolymer for improving compatibility with a thermoplastic or thermoset polymer matrix and a composition for the modified inorganic tubule and for the modified inorganic tubule-polymer matrix are provided. In one embodiment, the block copolymer can be added to a slurry of the inorganic tubules. The pH of the slurry can be manipulated to promote ionic bonding between the inorganic tubules and one block of the block copolymer. The other block of the block copolymer is selected for compatibility with the polymer matrix for a particular application. | 08-21-2008 |
20120329911 | Reactive Block Copolymers as Additives for the Preparation of Silicate-Polymer Composites - A process for making a block copolymer compatibilizer comprises reacting an acrylic and/or vinyl monomer that has functional groups with one or more vinyl monomers in the presence of a free radical initiator and a stable free radical to form a reaction product that includes residual unreacted acrylic and/or vinyl monomer, and reacting one or more vinyl monomers with the reaction product to form a second block that incorporates the residual unreacted acrylic monomer. The block copolymer is used to compatibilize a clay nanocomposite material with a thermoplastic or thermoset resin. The block copolymer can be used with existing, commercially-available clays, or the block copolymer can be formed with a polar block that is miscible in a polar dispersion medium for use as a intercalate in producing a clay nanocomposite material. | 12-27-2012 |
Maria Dolores Blanco Gonzalez, Mostoles - Madrid ES
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20160068631 | PROCESS FOR PREPARING HIGHLY ACTIVE DOUBLE METAL CYANIDE CATALYSTS AND THEIR USE IN THE SYNTHESIS OF POLYETHER POLYOLS - The present invention relates to a double metal cyanide (DMC) complex catalyst with an improved catalytic activity useful for epoxide polymerization. It also relates to polyether polyols prepared by a polymerization reaction using said DMC catalyst. | 03-10-2016 |
Maria Dolores Blanco Gonzalez, Madrid ES
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20140243497 | PROCESS FOR PREPARING HIGHLY ACTIVE DOUBLE METAL CYANIDE CATALYSTS AND THEIR USE IN THE SYNTHESIS OF POLYETHER POLYOLS - The present invention relates to a process of preparing a double metal cyanide (DMC) complex catalyst with an improved catalytic activity useful for epoxide polymerization. It also relates to the DMC catalyst obtainable by said process, as well as to polyether polyols prepared by a polymerization reaction using said DMC catalyst. | 08-28-2014 |
Maria Dolores Galvez Lopez, Murcia ES
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20150221877 | TRANSITION METAL COMPLEXES COMPRISING SYMMETRIC TETRADENTATE LIGANDS - Light emitting transition metal complexes comprising sub-units based on symmetric tetradentate ligands. | 08-06-2015 |
Maria Dolores García Vázquez, Barakaldo ES
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20110158963 | THREE-DIMENSIONAL MATRICES OF STRUCTURED POROUS MONETITE FOR TISSUE ENGINEERING AND BONE REGENERATION, AND METHOD OF THE PREPARATION THEREOF - The present invention is comprised within tissue engineering and, specifically, within bone regeneration. The invention relates to a porous three-dimensional matrix of monetite which is biocompatible, has structured porosity and is predefined and reabsorbable, as well as to the method of synthesis capable of producing said material and the applications thereof. These matrices are a perfect base for cell colonization and proliferation, allowing the application thereof in tissue engineering and bone regeneration as a result of their advantageous properties of biocompatibility, reabsorption, osteoinduction, revascularization, etc. | 06-30-2011 |
Maria Dolores Giraldez, Barcelona ES
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20150087525 | PLASMA MICRORNAS FOR THE DETECTION OF EARLY COLORECTAL CANCER - The present invention relates in general to the field of colorectal cancer detection, and more particularly, to plasma microRNAs for the detection of early colorectal cancer. Specifically, the present invention includes methods, kits and biomarkers for diagnosing or detecting colorectal neoplasia in a human subject comprising the steps of: A method for diagnosing or detecting colorectal neoplasia in a human subject comprising the steps of: obtaining one or more biological samples from the subject suspected of suffering from colorectal neoplasia; measuring an overall expression pattern or level of one or more microRNAs obtained from the one or more biological samples of the subject; and comparing the overall expression pattern of the one or more microRNAs from the biological sample of the subject suspected of suffering from colorectal neoplasia with the overall expression pattern of the one or more microRNAs from a biological sample of a normal subject, wherein the normal subject is a healthy subject not suffering from colorectal neoplasia, wherein overexpression of a combination of miR19a and miR19b, or miR19a and miR19b and miR15b is indicative of colorectal cancer. | 03-26-2015 |
20150176082 | PLASMA MICRORNAS FOR THE DETECTION OF EARLY COLORECTAL CANCER - The present invention relates in general to the field of colorectal cancer detection, and more particularly, to plasma microRNAs for the detection of early colorectal cancer. Specifically, the present invention includes methods, kits and biomarkers for diagnosing or detecting colorectal neoplasia in a human subject comprising the steps of: A method for diagnosing or detecting colorectal neoplasia in a human subject comprising the steps of: obtaining one or more biological samples from the subject suspected of suffering from colorectal neoplasia; measuring an overall expression pattern or level of one or more microRNAs obtained from the one or more biological samples of the subject; and comparing the overall expression pattern of the one or more microRNAs from the biological sample of the subject suspected of suffering from colorectal neoplasia with the overall expression pattern of the one or more microRNAs from a biological sample of a normal subject, wherein the normal subject is a healthy subject not suffering from colorectal neoplasia, wherein overexpression of a combination of miR19a and miR19b, or miR19a and miR19b and miR15b is indicative of colorectal cancer. | 06-25-2015 |
Maria Dolores Giráldez US
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20130102487 | PLASMA MICRORNAS FOR THE DETECTION OF EARLY COLORECTAL CANCER - The present invention relates in general to the field of colorectal cancer detection, and more particularly, to plasma microRNAs for the detection of early colorectal cancer. Specifically, the present invention includes methods, kits and biomarkers for diagnosing or detecting colorectal neoplasia in a human subject comprising the steps of: A method for diagnosing or detecting colorectal neoplasia in a human subject comprising the steps of: obtaining one or more biological samples from the subject suspected of suffering from colorectal neoplasia; measuring an overall expression pattern or level of one or more microRNAs obtained from the one or more biological samples of the subject; and comparing the overall expression pattern of the one or more microRNAs from the biological sample of the subject suspected of suffering from colorectal neoplasia with the overall expression pattern of the one or more microRNAs from a biological sample of a normal subject, wherein the normal subject is a healthy subject not suffering from colorectal neoplasia, wherein overexpression of a combination of miR19a and miR19b, or miR19a and miR19b and miR15b is indicative of colorectal cancer. | 04-25-2013 |
Maria Dolores Gomez Jimenez, Valencia ES
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20090089900 | Parthenocarpic tomatoes and production method thereof - The invention relates to parthenocarpic tomatoes ( | 04-02-2009 |
Maria Dolores Gurruchaga Torrecilla, Leioa (vizcaya) ES
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20140363392 | OSTEOINDUCTIVE COATINGS FOR DENTAL IMPLANTS - The present invention relates to an osteoinductive coating for use in dental implants, which can be obtained using a sol-gel process from methyltrimethoxysilane (MTMOS) as a silicon base precursor, ethyl tetraorthosilicate (TEOS) as a hydrophilic silicon precursor and at least one silicon precursor selected from glycidoxypropyltrimethoxysilane and aminopropyltrimethoxysilane. The invention also relates to the method for obtaining said coating and to the use thereof in dental implants. | 12-11-2014 |
Maria Dolores Gutierrez Lopez, Madrid ES
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20130338942 | METHOD AND SYSTEM FOR ESTIMATING THE FORCES AND TORQUES GENERATED BY THE CONTACT OF A TIRE WITH THE ROAD IN AN INSTRUMENTED WHEEL - The invention relates to a method for measuring the forces and the moments generated by the tire-road contact from the combination of unit deformation or strain signals measured in different angular and radial positions of the wheel. The angular positions in which the sensors are placed are those permitted by the geometry of the tire. The combination of deformation signals results in six or more signals that are independent of the angular position of the measuring sensors with respect to the tire-road contact point. The effect of temperature and loads that generate deformation signals that do not depend on said angular position of the measuring points, such as centrifugal forces, have been eliminated from the aforementioned signals. Said signals provide estimates of the loads by means of the resolution of two systems of linear equations with constant matrices and three unknowns each. | 12-19-2013 |
Maria Dolores Jimenez Bargueno, Alcobendas ES
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20110028475 | TETRAHYDROISOQUINOLINE SULFONAMIDE DERIVATIVES, THE PREPARATION THEREOF, AND THE USE OF THE SAME IN THERAPEUTICS - The disclosure relates to tetrahydroisoquinoline sulfonamide compounds of formula I: | 02-03-2011 |
20120323003 | TETRAHYDROISOQUINOLINE SULFONAMIDE DERIVATIVES, THE PREPARATION THEREOF, AND THE USE OF THE SAME IN THERAPEUTICS - The disclosure relates to tetrahydroisoquinoline sulfonamide compounds of formula I: | 12-20-2012 |
Maria Dolores Jimenez Bargueno, Paris FR
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20080269199 | ISOQUINOLINE AND BENZO[H]ISOQUINOLINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF AS ANTAGONISTS OF THE HISTAMINE H3 RECEPTOR - The invention concerns a compound of formula (I): | 10-30-2008 |
Maria Dolores Lorente Aroca, Valencia ES
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20120328875 | COMPOSITION FOR COATING - The method consists of the formation of a layer over a stone substrate to increase its hardness, chemical resistance, wear and scratch resistance, comprising applying on the substrate a coating matrix incorporating an organic material and fillers including inorganic nanoparticles and/or microparticles; chemically binding said matrix to the substrate, by a self-assembly process and/or a binding process by covalent bonding, electrostatic bonding, van der Waals bonding or hydrogen bonds; and finally drying said matrix. The mentioned organic material is selected from organosilanes, organophosphates, polycarboxylic compounds, compounds based on triazine heterocycles and said nanoparticles are nanoparticles of oxides, carbides, borides, nitrides of metals or of semimetals. | 12-27-2012 |
Maria Dolores Ludevid Mugica, Sant Just Desvern ES
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20100083403 | PRODUCTION OF PEPTIDES AND PROTEINS BY ACCUMULATION IN PLANT ENDOPLASMIC RETICULUM-DERIVED PROTEIN BODIES - A nucleic acid molecule is disclosed as containing a first nucleic acid sequence comprising a nucleotide sequence that encodes γ-zein protein, or a fragment thereof capable of directing and retaining a protein towards the endoplasmic reticulum (ER) of a plant cell; a second nucleic acid sequence containing a nucleotide sequence that encodes an amino acid sequence that is specifically cleavable by enzymatic or chemical means; and a third nucleic acid sequence containing the nucleotide sequence that encodes a peptide or protein of interest. Methods of using this nucleic acid molecule for transforming host plant cells and producing the peptide or protein of interest are also disclosed. | 04-01-2010 |
20150335720 | PRODUCTION OF BIOLOGICALLY ACTIVE PROTEINS - A fusion protein that is expressed in a recombinant protein body-like assembly (RPBLA) in host eukaryotic cells and organisms is disclosed. More particularly, a biologically active polypeptide fused to a protein sequence that mediates the induction of RPBLA formation is expressed and accumulated in host cells after transformation with an appropriate vector. The eukaryotic host cell does not produce protein bodies in the absence of the fusion protein. Methods for preparing and using the RPBLAs and the fusion protein are also disclosed, as are nucleic acid molecules that encode the fusion proteins. | 11-26-2015 |
Maria Dolores Ludevid Múgica, Sant Just Desvern ES
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20110305718 | Recombinant Protein Body-Inducing Polypeptides - Polypeptide sequences for inducing recombinant protein bodies are described. The sequences comprise a polyproline II (PPII) structure and/or a proline-rich sequence between two cysteine residues on either end. Recombinant protein bodies are useful for protein production because they allow for simple and efficient purification of high quantities of recombinant protein. In addition, other methods of using recombinant protein bodies, for example, in vaccination and food products, are also described. | 12-15-2011 |
Maria Dolores Luque De Castro, Cordoba ES
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20120141435 | USE OF OLIVE LEAF EXTRACTS IN A PHARMACEUTICAL COMPOSITION FOR INDUCING ANGIOGENESIS AND VASCULOGENESIS - The invention relates to the use of olive leaf extracts for producing a pharmaceutical composition capable of inducing angiogenesis and vascularization. In general, the composition can be used for therapeutic applications in order to promote the differentiation of stem cells into endothelial progenitor cells (EPCs) and/or mature endothelial cells, as well as to induce the vessel formation from said endothelial cells. The vascularization-inducing angiogenic composition of the invention is intended for, inter alia, cardiovascular disease, ischemic processes in general, ulcers, and wound healing in both human and veterinary medicine. | 06-07-2012 |
Maria Dolores Martinez Villagran, Mason, OH US
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20150173397 | PET FOOD COMPOSITION HAVING PROBIOTIC BIFIDOBACTERIUM ANIMALIS - A probiotic coated kibble having internal glycerin. | 06-25-2015 |
Maria Dolores Martin Ortega Finger, Madrid ES
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20100160340 | PROTEIN KINASE INHIBITORS - The present invention provides a compound of formula (I): | 06-24-2010 |
Maria Dolores Pérez-Guirao, Hannover DE
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20120224713 | WIRELESS AUDIO TRANSMISSION SYSTEM, PARTICULARLY A WIRELESS MICROPHONE SYSTEM - There is provided a wireless audio transmission system, in particular a wireless microphone system, for wireless audio transmission. The system has at least one wireless microphone unit for detecting audio signals and for wirelessly transmitting the detected audio signals, and a central unit. The central unit has a wireless receiving unit for receiving the wirelessly transmitted audio signals from The wireless microphone units, a pilot tone transmitting unit for transmitting a first pilot tone on a pilot channel, and a pilot tone receiving unit for receiving and processing a second pilot tone signal. The pilot tone signal has information in respect of the wireless transmission between the microphone units and the central unit. | 09-06-2012 |
Maria Dolores Real García, Burjassot (valencia) ES
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20100080860 | Application of short-chain monocarboxylic acids for crop protection - The present invention relates to the agricultural use of hexanoic acid and monocarboxylic acids with similar chain structure having from 5 to 8 carbon atoms, their derivatives, their salts, and aqueous mixtures thereof containing modified hexoses and/or amines. These compounds are useful as plant growth stimulants, anti-senescents, and as resistance inducers to biotic and abiotic stresses. The invention also refers to the use of caproic (hexanoic) acid as an inhibitor of spore germination and mycelium growth of phytopathogenic fungi. The use of hexanoic acid as a fungicide in both pre- and post-harvest treatments is also suggested. The inducing activity of hexanoic acid on plant defenses against phytopathogenic fungi at non-phytotoxic concentrations has been shown. | 04-01-2010 |
Maria Dolores Real García, Burjassot (valencia) ES
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20100080860 | Application of short-chain monocarboxylic acids for crop protection - The present invention relates to the agricultural use of hexanoic acid and monocarboxylic acids with similar chain structure having from 5 to 8 carbon atoms, their derivatives, their salts, and aqueous mixtures thereof containing modified hexoses and/or amines. These compounds are useful as plant growth stimulants, anti-senescents, and as resistance inducers to biotic and abiotic stresses. The invention also refers to the use of caproic (hexanoic) acid as an inhibitor of spore germination and mycelium growth of phytopathogenic fungi. The use of hexanoic acid as a fungicide in both pre- and post-harvest treatments is also suggested. The inducing activity of hexanoic acid on plant defenses against phytopathogenic fungi at non-phytotoxic concentrations has been shown. | 04-01-2010 |
Maria Dolores Sanchez-Garcia, Paterna ES
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20140187413 | NANOCOMPOSITE MATERIALS BASED ON METAL OXIDES HAVING MULTI-FUNCTIONAL PROPERTIES - The present invention relates to nanocomposite materials comprising nanoclays as support of metal oxide particles which give the materials multi-functional properties. Said properties are obtained through the formulation of a specific type of additives based on layers of natural and/or synthetic clays which are intercalated with metal oxides with antimicrobial and/or oxygen sequestrating and/or catalytic and/or self-cleaning and/or anti-abrasive capacity; and which may optionally contain other organic, metal, inorganic compounds or combination thereof which may exercise a role of compatibilization and/or dispersion and/or increase in the functionality of the metal oxides and/or providing new functionalities, both passive of physical strengthening and active such as biocide character, antioxidant and chemical-species absorbers. | 07-03-2014 |
Maria Dolores Tobalina Maestre, Barcelona ES
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20100087365 | Pharmaceutical Compositions of Hglp-1, Exendin-4 and Analogs Thereof - The present invention is directed to pharmaceutical composition comprising a clear solution or an aqueous mixture, a suspension or a semisolid of at least one peptide compound selected from the group consisting of hGLP-1(7-36)-NH | 04-08-2010 |
20100137204 | GLP-1 PHARMACEUTICAL COMPOSITIONS - The present invention is directed to peptide analogues of glucagon-like peptide-1, the pharmaceutically-acceptable salts thereof, to methods of using such analogues to treat mammals and to pharmaceutical compositions useful therefore comprising said analogues. | 06-03-2010 |
20120277151 | GLP-1 PHARMACEUTICAL COMPOSITIONS - The present invention is directed to peptide analogues of glucagon-like peptide-1, the pharmaceutically-acceptable salts thereof, to methods of using such analogues to treat mammals and to pharmaceutical compositions useful therefore comprising said analogues. | 11-01-2012 |
Maria Dolores Vallecillo Alvarez, Madrid ES
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20140080517 | METHOD FOR MOBILE LOCATION IN A WIRELESS NETWORK OFFERING LOCATION-BASED SERVICES - It comprises: | 03-20-2014 |
María Dolores Marcos MartÍnez, Valencia ES
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20150306037 | RELEASE OF SUBSTANCES IN SENESCENT CELLS - The invention relates to nanodevices for the controlled release of substances which comprises a support coated in oligosaccharides, wherein said oligosaccharides comprise at least 3 units of monosaccharides, and wherein at least one of the monosaccharides is galactose. These nanodevices release their load specifically in senescent cells. The invention also encompasses the method of obtainment and its uses. | 10-29-2015 |
María Dolores Pastor Herrera, Sevilla ES
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20150338422 | METHOD FOR OBTAINING DATA THAT ARE USEFUL FOR THE DIAGNOSIS, PROGNOSIS AND CLASSIFICATION OF PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) AND/OR LUNG CANCER - The invention describes a method for obtaining data useful for the diagnosis, prognosis and classification of individuals with chronic obstructive pulmonary disease (COPD) and/or lung cancer, diagnostic kit, device and uses thereof for the diagnosis, prognosis and classification of patients as a) individuals with no COPD or lung cancer, b) individuals with COPD, c) individuals with adenocarcinoma, d) individuals with COPD and adenocarcinoma, or e) individuals with COPD and squamous carcinoma | 11-26-2015 |
María Dolores Romero Sánchez, Valencia ES
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20110293837 | COMPOSITION AND PROCEDURE FOR APPLYING PHASE CHANGE MATERIALS (PCMS) TO NATURAL STONE - The present invention relates to a composition of phase change materials (PCMs) and to the application thereof to natural stone in order to improve the thermal properties of same. Different PCMs are used depending on the type of stone and the manner in which they are introduced into or applied to the stone. The use of PCMs in powder form, emulsions, etc., depends on the porosity of the stone and the manner in which the PCMs are applied. PCMs are added to natural stone: as a surface layer on the stone, as a mastic applied to the posterior surface of the natural stone, as a reinforcing layer (for example in the form of mortar) applied to the posterior surface of the natural stone, or by impregnation through immersion of the stone in a PCMcontaining solution. | 12-01-2011 |
María Dolores Zafra, Mostoles ES
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20150050204 | CATALYST FOR SELECTIVE OXIDATION OF SULPHUR COMPOUNDS - The present invention is related to a catalyst supported for the selective oxidation of sulphur compounds of the tail gas from the Claus process or streams with an equivalent composition to elemental sulphur or sulphur dioxide (SO | 02-19-2015 |