Patent application number | Description | Published |
20100042190 | IMPLANTABLE MEDICAL LEAD HAVING REDUCED DIMENSION TUBING TRANSITION - Lead body designs for forming a fluid tight seal between a multilumen tube and other portions of a lead body are provided. One lead body design has a multilumen tube having a first portion defining a first number of lumens and a second reduced dimension portion defining a second number of lumens, the second number of lumens being smaller than the first number of lumens. The reduced dimension portion is attached to a distal tip portion of the lead body, forming a fluid tight passageway through the multilumen tube to the distal tip portion. Also provided are methods for forming such multilumen tubes and incorporating such multilumen tubes into a lead body. | 02-18-2010 |
20100305672 | TIP ASSEMBLY FOR MEDICAL ELECTRICAL LEAD - An implantable lead may include a coupler, a fixation helix secured to the coupler and a guide element that includes an engaging surface and a proximal bearing surface. The engaging surface may be configured to engage the fixation helix such that the engaging surface of the guide element interacts with the fixation helix to cause the fixation helix to translate longitudinally when the fixation helix is rotated against the engaging surface. Longitudinal translation of the coupler and fixation helix may be limited by the distal end of the coupler contacting the proximal bearing surface of the guide element. | 12-02-2010 |
20110009939 | LAMINATE DISTAL LEAD SEAL WITH TISSUE INGROWTH FEATURE - An implantable lead may include a housing and a laminate distal seal disposed across a distal end of the housing. A coupler and a fixation helix secured to the coupler may be disposed within the housing. The fixation helix may have a retracted position in which the fixation helix does not penetrate the laminate distal seal and an extended position in which the fixation helix has pierced the laminate distal seal and extends therethrough. | 01-13-2011 |
20120253444 | IMPLANTABLE MEDICAL LEAD HAVING REDUCED DIMENSION TUBING TRANSITION - Lead body designs for forming a fluid tight seal between a multilumen tube and other portions of a lead body are provided. One lead body design has a multilumen tube having a first portion defining a first number of lumens and a second reduced dimension portion defining a second number of lumens, the second number of lumens being smaller than the first number of lumens. The reduced dimension portion is attached to a distal tip portion of the lead body, forming a fluid tight passageway through the multilumen tube to the distal tip portion. Also provided are methods for forming such multilumen tubes and incorporating such multilumen tubes into a lead body. | 10-04-2012 |
20130245737 | IMPLANTABLE MEDICAL LEAD HAVING REDUCED DIMENSION TUBING TRANSITION - Lead body designs for forming a fluid tight seal between a multilumen tube and other portions of a lead body are provided. One lead body design has a multilumen tube having a first portion defining a first number of lumens and a second reduced dimension portion defining a second number of lumens, the second number of lumens being smaller than the first number of lumens. The reduced dimension portion is attached to a distal tip portion of the lead body, forming a fluid tight passageway through the multilumen tube to the distal tip portion. Also provided are methods for forming such multilumen tubes and incorporating such multilumen tubes into a lead body. | 09-19-2013 |
Patent application number | Description | Published |
20090230167 | Endostapler Biasing Mechanism - An endostapler delivery system includes a biasing mechanism to offset or counter forces generated by a stapling device and therefore prevent the stapling device from moving during the firing of the staple. The delivery system includes a catheter having at least one lumen extending there through for receiving the stapling device. The biasing mechanism is an expandable biasing cage having a dome or semi-circular expanded shape provided at the distal portion of the catheter. When expanded, the biasing cage does not block or occlude a vessel, thereby allowing blood flow to continue during the stapling procedure. The biasing cage may include a plurality of ribbons or strands that extend generally parallel to the blood flow when expanded in situ, a mesh or braided structure, or a plurality of ribbons or strands that extend generally parallel to the blood flow when expanded in situ and a mesh or braided structure placed over the plurality of ribbons. | 09-17-2009 |
20090230169 | Endostapler Biasing Mechanism - An endostapler delivery system includes a biasing mechanism to offset or counter forces generated by a stapling device and therefore prevent the stapling device from moving during the firing of the staple. The delivery system includes a catheter having at least one lumen extending there through for receiving the stapling device. The biasing mechanism is an expandable biasing cage having a dome or semi-circular expanded shape provided at the distal portion of the catheter. When expanded, the biasing cage does not block or occlude a vessel, thereby allowing blood flow to continue during the stapling procedure. The endostapler delivery system further includes a steering wire that can be used to bend the catheter shaft. | 09-17-2009 |
20100044410 | Endovascular Stapling Apparatus and Methods of Use - An endovascular stapling apparatus for delivering a staple to a vessel of a patient, including a plurality of clips, a housing, and a rod. Each of the clips includes a bridge and legs that self-transition from a biased state to a natural state in which the legs each form a loop. The housing defines a channel and a window open to the channel. The clips are retained within the channel in the biased state. The rod is slidably disposed within the channel, selectively moves the clips toward and away from the window, and releases the clips from the window. | 02-25-2010 |
20120029271 | Tissue Stabilizing Device and Methods Including a Self-Expandable Head-Link Assembly - A tissue stabilizer including an elongated arm, a collet, and a head-link assembly. The collet is disposed at a distal end of the arm. The head-link assembly includes a tube and a spreading mechanism. The tube forms an intermediate section and opposing arms each terminating at a tip. The spreading mechanism can adjust a lateral distance between the tips, and includes first and second articulating members each having a leg and a collet interface body. The first member further includes a female hinge feature, whereas the second member includes a male hinge feature differing from the female hinge feature. The legs of are mounted to discrete regions of the tube, and the male hinge feature is pivotably coupled to the female hinge feature. Automatic spreading of a lateral distance between the tips occurs in response to a compressive force applied to the collet interface bodies. | 02-02-2012 |
20130274547 | Tissue Stabilizing Device and Methods Including a Self-Expandable Head-Link Assembly - A tissue stabilizer including an elongated arm, a collet, and a head-link assembly. The collet is disposed at a distal end of the arm. The head-link assembly includes a tube and a spreading mechanism. The tube forms an intermediate section and opposing arms each terminating at a tip. The spreading mechanism can adjust a lateral distance between the tips, and includes first and second articulating members each having a leg and a collet interface body. The first member further includes a female hinge feature, whereas the second member includes a male hinge feature differing from the female hinge feature. The legs of are mounted to discrete regions of the tube, and the male hinge feature is pivotably coupled to the female hinge feature. Automatic spreading of a lateral distance between the tips occurs in response to a compressive force applied to the collet interface bodies. | 10-17-2013 |
Patent application number | Description | Published |
20080249546 | ANASTOMOSIS SYSTEMS AND METHODS - A surgical connection apparatus including a plurality of delivery assemblies, a housing assembly, and a drive mechanism. The delivery assemblies each include an outer member, an inner member, and optionally a retention member. The inner member is disposed within the outer member, terminates at a distal tip and forms an internal passage that is open at a window. The delivery assemblies releasably retain a self-closing clip. The housing assembly maintains the delivery assemblies in a generally circular arrangement. The drive mechanism operates to transition the delivery assembly in releasing a self-closing clip from the corresponding delivery assembly. With this construction, a plurality of self-closing clips can be simultaneously deployed in a manner effectuating, for example, an end-to-side anastomosis. | 10-09-2008 |
20090222026 | SURGICAL FASTENING CLIPS, SYSTEMS AND METHODS FOR PROXIMATING TISSUE - A surgical fastener clip for proximating tissue, the clip providing an undeflected state in which the clip comprises a center portion, a first leg, and a second leg. The center portion has a perimeter defining a circle-like shape. The legs project outwardly relative to the perimeter from a point of departure to a tip. Extension of each of the legs relative to the perimeter defines an identical wind direction that is either clockwise or counterclockwise. The clip optionally includes a linear cross-member extending across the perimeter. The surgical clip can be formed by a wire that is partially wound onto itself in a spiral-like fashion, with the center portion and the legs being co-planar in the undeflected state. During use, the clip is rotated, drawing tissue into the center portion. Systems incorporating the clip are also provided. | 09-03-2009 |
20100114136 | CUTTING DEVICE AND METHOD OF VESSEL HARVESTING - Embodiments of the invention provide a cutting device and method of vessel harvesting. The cutting device can include at least one tubular member, a cutting element, and a centering member. The cutting device can include at least one tubular member with a flexible section and a cutting element. The method of vessel harvesting can include spacing a cutting element of the cutting device from the vessel as the cutting element is advanced over the vessel. | 05-06-2010 |
20100121362 | VESSEL SUPPORT DEVICE AND METHOD OF VESSEL HARVESTING - Embodiments of the invention provide a vessel support system and a method of vessel harvesting. The system can include a cutting device, a catheter adapted to be inserted into a section of the vessel in order to support the vessel as the cutting device is advanced over the vessel, and a cannula adapted to be coupled to the vessel and adapted to receive the catheter as the catheter is inserted into the section of the vessel. The method can include orienting a cutting device coaxially with the cannula and the catheter and advancing the cutting device over the cannula, the catheter, and the section of the vessel in order to core out the section of the vessel and a portion of the surrounding tissue. | 05-13-2010 |
20130184727 | VESSEL SUPPORT DEVICE AND METHOD OF VESSEL HARVESTING - Embodiments of the invention provide a vessel support system and a method of vessel harvesting. The system can include a cutting device, a catheter adapted to be inserted into a section of the vessel in order to support the vessel as the cutting device is advanced over the vessel, and a cannula adapted to be coupled to the vessel and adapted to receive the catheter as the catheter is inserted into the section of the vessel. The method can include orienting a cutting device coaxially with the cannula and the catheter and advancing the cutting device over the cannula, the catheter, and the section of the vessel in order to core out the section of the vessel and a portion of the surrounding tissue. | 07-18-2013 |
Patent application number | Description | Published |
20100299440 | METHOD AND APPARATUS FOR SENDING DATA FROM MULTIPLE SOURCES OVER A COMMUNICATIONS BUS - In a memory system, multiple memory modules communicate over a bus. Each memory module may include a hub and at least one memory storage unit. The hub receives local data from the memory storage units, and downstream data from one or more other memory modules. The hub assembles data to be sent over the bus within a data block structure, which is divided into multiple lanes. An indication is made of where, within the data block structure, a breakpoint will occur in the data being placed on the bus by a first source (e.g., the local or downstream data). Based on the indication, data from a second source (e.g., the downstream or local data) is placed in the remainder of the data block, thus reducing gaps on the bus. Additional apparatus, systems, and methods are disclosed. | 11-25-2010 |
20120110255 | METHOD AND APPARATUS FOR SENDING DATA FROM MULTIPLE SOURCES OVER A COMMUNICATIONS BUS - In a memory system, multiple memory modules communicate over a bus. Each memory module may include a hub and at least one memory storage unit. The hub receives local data from the memory storage units, and downstream data from one or more other memory modules. The hub assembles data to be sent over the bus within a data block structure, which is divided into multiple lanes. An indication is made of where, within the data block structure, a breakpoint will occur in the data being placed on the bus by a first source (e.g., the local or downstream data). Based on the indication, data from a second source (e.g., the downstream or local data) is placed in the remainder of the data block, thus reducing gaps on the bus. Additional apparatus, systems, and methods are disclosed. | 05-03-2012 |
20130097395 | METHOD AND APPARATUS FOR SENDING DATA FROM MULTIPLE SOURCES OVER A COMMUNICATIONS BUS - In a memory system, multiple memory modules communicate over a bus. Each memory module may include a hub and at least one memory storage unit. The hub receives local data from the memory storage units, and downstream data from one or more other memory modules. The hub assembles data to be sent over the bus within a data block structure, which is divided into multiple lanes. An indication is made of where, within the data block structure, a breakpoint will occur in the data being placed on the bus by a first source (e.g., the local or downstream data). Based on the indication, data from a second source (e.g., the downstream or local data) is placed in the remainder of the data block, thus reducing gaps on the bus. Additional apparatus, systems, and methods are disclosed. | 04-18-2013 |
20140351502 | METHOD AND APPARATUS FOR SENDING DATA FROM MULTIPLE SOURCES OVER A COMMUNICATIONS BUS - In a memory system, multiple memory modules communicate over a bus. Each memory module may include a hub and at least one memory storage unit. The hub receives local data from the memory storage units, and downstream data from one or more other memory modules. The hub assembles data to be sent over the bus within a data block structure, which is divided into multiple lanes. An indication is made of where, within the data block structure, a breakpoint will occur in the data being placed on the bus by a first source (e.g., the local or downstream data). Based on the indication, data from a second source (e.g., the downstream or local data) is placed in the remainder of the data block, thus reducing gaps on the bus. Additional apparatus, systems, and methods are disclosed. | 11-27-2014 |
Patent application number | Description | Published |
20140131605 | KUSC Positive Return Valve Action - A kinetically unyielding, statically compliant (KUSC) positive return valve action. In one embodiment, a guide is pivotally mounted and rotationally abuts a limiting bench. A pin mounted slidably on the guide is linked to a poppet valve, a driver positioning the pin along the guide. With the valve seated and the driver overtraveled a deflection opens up between the guide and the limiting bench that resolves the overtravel, which deflection is opposed by a forcing spring. As the valve is initially lifted, valve-lift kinetic force is buttressed against the guide mount and the limiting bench, neither of which yields. With increasing lift the pin position passes the guide mount axis to be cantilevered on the guide at maximal valve lift against valve-return kinetic force: this also is unyieldingly buttressed. The action is adjusted by positioning the limiting bench either manually or by hydraulic lash adjuster. | 05-15-2014 |
20140338621 | Lost Motion Reciprocation Splitter - A driver that reciprocates has its reciprocation divided into a non-actuating portion and an actuating portion. The driver in one embodiment positions a carrier that has two pins, each pin being slidably mounted in its slot on a housing. One of the pins is an output pin that may be linked to operatively position a valve of an internal combustion engine. The two slots are configured such that each pin, during its motion range, does effect a capture of the other pin such that the captured pin is generally stationary. When the output pin is captured, the driver reciprocation causes the non-output pin to perform a lost-motion traverse of its slot. When the non-output pin is captured, the driver reciprocation actuates the output pin. A linked pair of such embodiments driven by a single driver can thus alternately actuate two valves. | 11-20-2014 |
20150053159 | Externally Driven Interior Axial Cam - An axial cam with a plurality of followers mounted within its diameter drives the followers in both axial directions. The followers operatively actuate valves such as those of an internal combustion engine. The cam can be driven about its exterior perimeter, providing an axially compact embodiment. The phasing of select followers can be established by modifying the azimuth positions of those followers with the cam in operation. By providing the cam with a symmetric actuating profile its followers can be linked to alternately actuate same-function valves in different engine cylinders. | 02-26-2015 |
Patent application number | Description | Published |
20100271819 | LIGHTING ASSEMBLIES AND SYSTEMS - The present disclosure relates to illumination or lighting assemblies and systems that provide illumination using LEDs. In one aspect, the present disclosure provides a lighting assembly, comprising: multiple light emitting diodes that emit light; an optical system that directs the light emitted by the light emitting diodes, the optical system positioned adjacent to light emitting diodes; and a cooling fin including a two-phase cooling system, the cooling fin positioned adjacent to the light emitting diodes such that the two-phase cooling system removes heat from the light emitting diodes. In another aspect, the present disclosure provides a lighting system including multiple lighting assemblies. The lighting assemblies and systems of the present disclosure can be used in, for example, a street light, a backlight (including, for example, a sun-coupled backlight), a wall wash light, a billboard light, a parking ramp light, a high bay light, a parking lot light, a signage lit sign (also referred to as an electric sign), static signage (including, for example, sun-coupled static signage), illuminated signage, and other lighting applications. | 10-28-2010 |
Patent application number | Description | Published |
20100236336 | MULIPLE DEGREE OF FREEDOM DISPLACEMENT TRANSDUCER - A multiple degree of freedom displacement transducer and body thereof is used to measure linear displacements along and/or rotational or pivotal displacements about up to three orthogonal axes. In one embodiment, a displacement transducer body includes a first pivoting assembly and a second pivoting assembly. Each pivoting assembly has a support member pivotable relative to another portion about two orthogonal axes. A structure joins said another portion of each pivoting assembly together. In another embodiment, a displacement transducer includes a first support member, a second support member, and a cross flexure assembly joining the first support member to the second support member. The cross flexure assembly is arranged to allow the first support member to pivot relative to the second support member about two intersecting orthogonal axes. An angular sensing device is arranged to provide an output signal related to angular movement of the first support member relative to the second support member about at least one of the orthogonal axes. | 09-23-2010 |
20100326206 | PLATFORM BALANCE - The present disclosure is directed to a platform balance that is suitable for transmitting forces and moments in a plurality of directions. The platform balance is adapted to support a test specimen, such as a large vehicle, in a test environment such as a wind tunnel. The platform balance includes a frame support and at least three spaced-apart transducers coupled to the frame support. Each of the transducers is sensitive about two orthogonal sensed axes. The transducers cooperate to provide signals indicative of forces and moments with respect to at least two orthogonal axes. Each transducer includes a transducer body having a support coupled to a sensor body along an axis of compliance. The sensor body is adapted to deflect about the two orthogonal sensed axes where the sensed axes are mutually orthogonal to the axis of compliance. | 12-30-2010 |
20150033875 | Two-Axis Sensor Body For A Load Transducer - In one aspect, a transducer body includes a support having clevis halves. The sensor body includes a generally rigid peripheral member disposed about a spaced-apart central hub joined to each of the clevis halves. At least three flexure components couple the peripheral member to the hub. The flexure components are spaced-apart from each other at generally equal angle intervals about the hub; the sensor body further including a flexure assembly for some flexure components joining the flexure component to at least one of the hub and the peripheral member, the flexure assembly being compliant for forces in a radial direction from the hub to the peripheral member. Each flexure assembly is configured such that forces transferred concentrate strain at a midpoint along the length of each corresponding flexure component. | 02-05-2015 |
Patent application number | Description | Published |
20080275522 | Non-captured intrinsic discrimination in cardiac pacing response classification - Cardiac devices and methods discriminate non-captured intrinsic beats during evoked response detection and classification by comparing the features of a post-pace cardiac signal with expected features associated with a non-captured response with intrinsic activation. Detection of a non-captured response with intrinsic activation may be based on the peak amplitude and timing of the cardiac signal. The methods may be used to discriminate between a fusion or capture beat and a non-captured intrinsic beat. Discriminating between possible cardiac responses to the pacing pulse may be useful, for example, during automatic capture verification and/or a capture threshold test. | 11-06-2008 |
20090069858 | Capture Detection for Multi-Chamber Pacing - Multi-chamber pacing may result in capture of one chamber, capture of multiple chambers, fusion, or non-capture. Approaches for detecting various capture conditions during multi-chamber pacing are described. Pacing pulses are delivered to left and right heart chambers during a cardiac cycle. A cardiac electrogram signal is sensed following the delivery of the pacing pulses. Left chamber capture only, right chamber capture only, and bi-chamber capture may be distinguished based on characteristics of the cardiac electrogram signal. Multi-chamber capture detection may be implemented using detection windows having dimensions of time and amplitude. The detection windows are associated with expected features, such as expected signal peaks, under a particular capture condition. The cardiac electrogram signal features are compared to detection windows to determine the capture condition. | 03-12-2009 |
20100023078 | Cardiac resynchronization therapy parameter optimization - Systems and methods involve determination of CRT parameters using a number of CRT optimization processes. Each CRT optimization process attempts to return recommended parameters. The CRT parameters are determined based on the recommended parameters returned by one or more of the CRT optimization processes. The CRT optimization processes may be sequentially implemented and the CRT parameters may be determined based on the recommended parameters returned by a first CRT optimization process to return recommended parameters. The CRT parameters may be determined based on a combination of the recommended parameters returned. The CRT optimization processes implemented may be selected from available CRT optimization processes based on patient conditions. | 01-28-2010 |
20120165895 | Non-Captured Intrinsic Discrimination in Cardiac Pacing Response Classification - Cardiac devices and methods discriminate non-captured intrinsic beats during evoked response detection and classification by comparing the features of a post-pace cardiac signal with expected features associated with a non-captured response with intrinsic activation. Detection of a non-captured response with intrinsic activation may be based on the peak amplitude and timing of the cardiac signal. The methods may be used to discriminate between a fusion or capture beat and a non-captured intrinsic beat. Discriminating between possible cardiac responses to the pacing pulse may be useful, for example, during automatic capture verification and/or a capture threshold test. | 06-28-2012 |
20120330372 | Methods and Systems for Selecting Capture Verification Modes - Methods and systems are directed to selecting from a variety of capture verification modes. A plurality of capture verification modes, including a beat by beat capture detection mode and a capture threshold testing mode without intervening beat by beat capture detection is provided. An efficacy of at least one of the capture verification modes is evaluated, and based on the evaluation, a capture verification mode is selected. | 12-27-2012 |
20130013020 | Methods and Systems for Managing Fusion and Noise in Cardiac Pacing Response Classification - Methods and systems for detecting noise in cardiac pacing response classification processes involve determining that a cardiac response classification is possibly erroneous if unexpected signal content is detected. The unexpected signal content may comprise signal peaks that have polarity opposite to the polarity of peaks used to determine the cardiac response to pacing. Fusion/noise management processes include pacing at a relatively high energy level until capture is detected after a fusion, indeterminate, or possibly erroneous pacing response classification is made. The relatively high energy pacing pulses may be delivered until capture is detected or until a predetermined number of paces are delivered. | 01-10-2013 |
Patent application number | Description | Published |
20090280322 | ADHESIVE COMPOSITIONS, ADHESIVE ARTICLES AND METHODS FOR MAKING THE SAME - Adhesive compositions comprising a high molecular weight acrylic copolymer and a low molecular weight copolymer are disclosed. Adhesive articles and methods of making adhesive compositions and articles are also described. | 11-12-2009 |
20110151168 | MULTI-LAYER OPTICAL ARTICLES - Multi-layer articles are disclosed which include, a polypropylene-based film, and a layer on at least one surface of the polypropylene-based film including an ethylene-based material containing a copolymer of ethylene and at least one alpha-olefin comomoner with a density of no greater than 0.90 g/cm | 06-23-2011 |
20120276379 | ADHESIVE COMPOSITIONS, ADHESIVE ARTICLES AND METHODS FOR MAKING THE SAME - Adhesive compositions comprising a high molecular weight acrylic copolymer and a low molecular weight copolymer are disclosed. Adhesive articles and methods of making adhesive compositions and articles are also described. | 11-01-2012 |
20140171538 | ADHESIVE COMPOSITIONS, ADHESIVE ARTICLES AND METHODS FOR MAKING THE SAME - Adhesive compositions comprising a high molecular weight acrylic copolymer and a low molecular weight copolymer are disclosed. Adhesive articles and methods of making adhesive compositions and articles are also described. | 06-19-2014 |
20150040981 | DURABLE PHOTOVOLTAIC MODULES - The present disclosure generally relates to durable photovoltaic modules, methods of making durable photovoltaic modules, and constructions including durable photovoltaic cells and modules. | 02-12-2015 |
Patent application number | Description | Published |
20120273354 | MULTIMODAL DIALYSIS SYSTEM - A dialysis device for operation in multiple modes and for maintaining a known gradient of potassium ion or other electrolyte between the blood of a patient and a dialysate fluid is described. The dialysis device is capable of being used for hemodialysis or peritoneal dialysis, and the dialysis device is capable of operation with a dialysate purification unit outside of a clinical setting or with a supply of water that can be supplied in a clinical setting. The dialysis device has a composition sensor containing a potassium-sensitive electrode for measuring a potassium ion concentration in one or more of the patient's blood and the dialysate fluid and an infusate pump operated to adjust a potassium ion concentration in the dialysate fluid based at least in part on data from the composition sensor. | 11-01-2012 |
20130070423 | COMPACT CONNECTOR ASSEMBLY FOR IMPLANTABLE MEDICAL DEVICE - A connector assembly for an implantable medical device includes a plurality of feedthroughs mounted in a conductive array plate, each feedthrough in the plurality of feedthroughs including a feedthrough pin electrically isolated from the conductive array plate by an insulator and an electronic module assembly including a plurality of conductive strips set in a non-conductive block. The plurality of conductive strips is in physical and electrical contact with the feedthrough pins at an angle of less than 135 degrees. The connector assembly further includes at least one circuit, the circuit including a plurality of conductors corresponding to the plurality of feedthroughs. The plurality of conductors of the circuit is in physical and electrical contact with a corresponding one of the conductive strips of the plurality of conductive strips of the electronic module assembly at an angle of less than 135 degrees. | 03-21-2013 |
20130199998 | HEMODIALYSIS SYSTEM HAVING A FLOW PATH WITH A CONTROLLED COMPLIANT VOLUME - Systems and methods for the performance of kidney replacement therapy having or using a dialyzer, control components, sorbent cartridge and fluid reservoirs configured to be of a weight and size suitable to be worn or carried by an individual requiring treatment are disclosed. The system for performing kidney replacement therapy has a controlled compliance dialysis circuit, where a control pump controls the bi-directional movement of fluid across a dialysis membrane. The dialysis circuit and an extracorporeal circuit for circulating blood are in fluid communication through the dialysis membrane. The flux of fluid moving between the extracorporeal circuit and the dialysis circuit is modified by the rate at which the control pump is operating such that a rate of ultrafiltration and convective clearance can be controlled. The system provides for the monitoring of an inlet and outlet conductivity of the sorbent cartridge to provide a facility to quantify or monitor the removal of urea by the sorbent cartridge. | 08-08-2013 |
20130213890 | MODULAR HEMODIALYSIS SYSTEM - Apparatuses, systems, and methods for the performance of kidney replacement therapy having or using a dialyzer, control components, sorbent cartridge, and fluid reservoirs configured to be of a weight and size suitable to be worn or carried by an individual requiring treatment are disclosed. The system has a controlled compliance dialysis circuit, where a control pump controls the bi-directional movement of fluid across a dialysis membrane. A first sorbent cartridge is provided for use in a portable treatment module having activated carbon and zirconium oxide. The system also provides for the monitoring of an inlet and outlet conductivity of a sorbent cartridge containing urease to provide a facility to quantify or monitor the removal of urea by a detachable urea removal module. | 08-22-2013 |
20140158538 | POTASSIUM LOADED ION-EXCHANGE MATERIAL FOR USE IN A DIALYSATE REGENERATION SYSTEM - Systems and methods for managing the potassium concentration of a dialysate fluid during hemodialysis therapy using cation exchange materials that do not release sodium ions. | 06-12-2014 |
20140158588 | pH AND BUFFER MANAGEMENT SYSTEM FOR HEMODIALYSIS SYSTEMS - Systems and methods for managing the pH of a dialysate fluid during hemodialysis therapy. The systems and methods adjust dialysate pH and buffer concentration to generate a predetermined total bicarbonate buffer concentration in a dialysate entering a dialyzer. | 06-12-2014 |
20140158623 | SODIUM MANAGEMENT FOR HEMODIALYSIS - Systems and methods for managing the sodium concentration of a dialysate fluid during hemodialysis therapy and adjusting sodium concentration using a sodium management system to generate a sodium-modified fluid. The systems and methods also provide a mechanism for controlled addition of sodium ions to the dialysate to generate a predetermined total sodium concentration in a dialysate. | 06-12-2014 |
20140190876 | SORBENT CARTRIDGE TO MEASURE SOLUTE CONCENTRATIONS - A sorbent based monitoring system for measuring the solute concentration of at least one component of a fluid. The system has a sorbent regeneration system for regeneration of the fluid and has a sorbent cartridge that has at least one material layer. The fluid is conveyed through the sorbent cartridge and contacts at least one sensor after having contacted at least one material layer. | 07-10-2014 |
20140190885 | FLUID CIRCUITS FOR SORBENT CARTRIDGE WITH SENSORS - A system for measuring at least one fluid characteristic at various stages within a sorbent system that has a sorbent cartridge that has at least one material layer and at least one fluid passageway in at least one location in the sorbent system to provide a diverted sample stream from the various stages. At least one fluid characteristic of the diverted sample stream is measured. | 07-10-2014 |
20140190886 | RECIRCULATING DIALYSATE FLUID CIRCUIT FOR BLOOD MEASUREMENT - A blood based solute monitoring system for measuring at least one blood solute species that has a first recirculation flow path in fluid communication with a dialyzer. The first recirculation flow path is configured to allow a fluid to recirculate through a dialyzer such that the concentration of at least one solute species in the fluid becomes equilibrated to the solute species concentration of the blood in a blood compartment of the dialyzer. The blood solute monitoring system has at least one sensor to measure a fluid characteristic. | 07-10-2014 |
20140190891 | SORBENT CARTRIDGE WITH ELECTRODES - A sorbent cartridge that has at least one sensor located within the sorbent cartridge. | 07-10-2014 |
20140216250 | DEGASSING MODULE FOR A CONTROLLED COMPLIANT FLOW PATH - A degassing module for removal of air and other gases during operation of a medical therapy device that delivers any one of hemodialysis, hemodiafiltration and hemofiltration. The degassing module has a flow-through first chamber that has a hydrophobic vent membrane that has an exterior and interior side forming a portion of the flow-through chamber. The hydrophobic vent membrane is positioned at a higher elevation on the flow-through chamber than a fluid outlet. Fluid flows through the flow-through chamber in a downward direction relative to the hydrophobic vent membrane. A flow-through chamber has a cross sectional area configured to provide for a downward flow velocity of the fluid to be less than the upward rise velocity of a smallest bubble to be removed from the fluid. | 08-07-2014 |
20140217020 | MODULAR FLUID THERAPY SYSTEM HAVING JUMPERED FLOW PATHS AND SYSTEMS AND METHODS FOR CLEANING AND DISINFECTION - Systems and methods for cleaning and disinfecting a medical therapy device that delivers any one of hemodialysis, hemodiafiltration and hemofiltration. The system has a base module that has at least one segment of a controlled compliant flow path and at least one pair of jumpered ports configured on the base module. One or more components have connections connectable to the jumpered ports of the base module to provide for fluid communication between the segment of the controlled compliant flow path in the base module and a flow path defined by the one or more components. The base module is connected to the one or more components that define a flow path configurable for carrying out in part at least one function performed during any one of hemodialysis, hemodiafiltration or hemofiltration. | 08-07-2014 |
20140217027 | SYSTEMS AND METHODS FOR MULTIFUNCTIONAL VOLUMETRIC FLUID CONTROL - Systems and methods for controlling fluid movement and volumes of fluid between a subject and a controlled compliant flow path. The controlled compliant flow path has a means for selectively metering in and metering out fluid from the controlled compliant flow path. An extracorporeal flow path is in fluid communication with the controlled compliant flow path across a semi-permeable membrane where the extracorporeal flow path has a first terminal end and a second terminal end. | 08-07-2014 |
20140217028 | SORBENT CARTRIDGE CONFIGURATIONS FOR IMPROVED DIALYSATE REGENERATION - A regeneration system that has a first regeneration module containing a first chosen regenerative substance; a second regeneration module containing the first chosen regenerative substance; and a first mixing chamber. A first outlet stream of a fluid sequentially exits the first mixing chamber, flows through the first regeneration module in fluid communication with the first chosen regenerative substance and returns to the first mixing chamber, and a second outlet stream of the fluid sequentially exits the first mixing chamber and flows through the second regeneration module in fluid communication with the first chosen regenerative substance. | 08-07-2014 |
20140217029 | FLUID CIRCUIT FOR DELIVERY OF RENAL REPLACEMENT THERAPIES - A flow loop for hemodialysis, hemodiafiltration and hemofiltration for the treatment of pathological conditions such as End Stage Renal Disease (ESRD) that has a controlled compliant flow path for preparing fluids required for a hemodialysis therapy session from water. The controlled compliant flow path modifies water into any one of a solution for priming a hemodialysis system, a physiologically compatible solution for contacting blood, a physiologically compatible solution for infusion to a subject, and a solution for blood rinse back to a subject. The controlled compliant flow path has a means for selectively metering in and metering out fluid from the flow path. | 08-07-2014 |
20140217030 | SODIUM AND BUFFER SOURCE CARTRIDGES FOR USE IN A MODULAR CONTROLLED COMPLIANT FLOW PATH - Systems and methods for using a sodium chloride source and a buffer source such as sodium bicarbonate in a controlled compliant flow path to generate from water a physiologically compatible fluid having a suitable level of a sodium ion and/or a buffer for use in hemodialysis, hemodiafiltration and hemofiltration. The system has a conditioning flow path that has at least a salination valve or salination pump, and at least one container has at least one solute in excess of the solubility of that solute. At least one of the solutes is a buffer source or sodium chloride. The conditioning flow path is in fluid communication with a controlled compliant flow path. The conditioning flow path can selectively meter fluid into and out of the controlled compliant flow path. | 08-07-2014 |
20140220699 | pH BUFFER MEASUREMENT SYSTEM FOR HEMODIALYSIS SYSTEMS - A pH-buffer measurement system that has at least one source for modifying the pH of a fluid entering the system, the source selected from an acid source and a base source. The acid source adds an acid equivalent to provide an acid reacted fluid and the base source adds a base equivalent to provide a base reacted fluid. The source is in fluid communication with a flow path and a component for determining a fluid characteristic of the acid reacted fluid or the base reacted fluid. The fluid characteristic that is measured is any one of a gas phase pressure, an electrical conductivity, or thermal conductivity. | 08-07-2014 |
20150083647 | Portable Dialysis Cabinet - A portable dialysis cabinet for use in dialysis. The portable dialysis cabinet can have a size and weight that facilitates easy movement of the cabinet from one location to another with relative ease. The portable dialysis cabinet can have additional features necessary to facilitate portability, such as wheels and a handle. In general, the portable dialysis cabinet can contain all the necessary components for performing a dialysis session. | 03-26-2015 |
Patent application number | Description | Published |
20090278696 | SYSTEM AND METHOD FOR PROVIDING ENHANCED WEIGHT ALERT NOTIFICATION DURING AUTOMATED PATIENT MANAGEMENT - A system and method for providing enhanced weight alert notification during automated patient management is presented. A plurality of weight measurements in an automated patient environment from a weight monitoring device for a patient during an observation period is remotely obtained. A raw baseline weight for the patient is determined based on a function of the weight measurements. Irregularities in the weight measurements are identified. The raw baseline weight is processed into a baseline weight by application of a correction coefficient to the irregularities. Weight remotely measured in the automated patient environment for the patient on a substantially regular basis is obtained. Changes in the weight are identified by periodic comparison to the baseline weight. An alert notification is generated in response to the change in weight. | 11-12-2009 |
20130046196 | SYSTEMS AND METHODS FOR SETTING PARAMETERS OF IMPLANTABLE MEDICAL DEVICES USING PREDICTIVE MARKER DATA - Embodiments of the invention are related to systems and methods for setting parameters of implantable medical devices, amongst other things. In an embodiment, the invention includes a method for programming an implantable medical device including sensing concentrations of a predictive marker such as ET-1 in a patient, selecting programming parameter values based on the sensed concentrations of the predictive marker, and implementing the selected programming parameter values. In an embodiment the invention includes a method for detecting arrhythmia in a patient including sensing concentrations of the predictive marker in a patient, selecting a level of stringency to be used in an arrhythmia detection module based on the sensed concentrations of the predictive marker, sensing electrical signals in the patient, and evaluating the sensed electrical signals for indicia of an arrhythmia using the arrhythmia detection module. Other embodiments are also included herein. | 02-21-2013 |
20130196870 | SYSTEMS AND METHODS USING BIOMARKER PANEL DATA - Embodiments of the disclosure are related to systems and methods for utilizing biomarker panel data and related medical devices and methods, amongst other things. An embodiment can include a method of screening patients. The method can include quantifying levels of one or more of a panel of biomarkers in a biological sample of a patient. The method can further include analyzing the quantified levels. In some embodiments, the panel of biomarkers includes at least two selected from the group consisting of CRP, SGP-130, sIL-2R, sTNFR-II, IFNg, BNP, sST2, MMP-2, MMP-9, TIMP-1, TIMP-2, TIMP-4. In an embodiment, the disclosure can include a method of diagnosing a patient. The method can include quantifying levels of one or more of a panel of biomarkers in a biological sample of a patient. The method can further include diagnosing the patient based at least in part on the quantified levels. In some embodiments, the panel of biomarkers includes at least two selected from the group consisting of CRP, SGP-130, sIL-2R, sTNFR-II, IFNg, BNP, sST2, MMP-2, MMP-9, TIMP-1, TIMP-2, TIMP-4. Other embodiments are also included herein. | 08-01-2013 |
20130237439 | SYSTEMS AND METHODS USING BIOMARKER PANEL DATA - Embodiments of the disclosure are related to systems and methods for utilizing biomarker panel data with respect to medical devices and methods, amongst other things. In an embodiment, the disclosure can include a method of predicting the likelihood of response to CRT therapy. The method can include quantifying levels of one or more biomarkers in a biological sample of a patient, analyzing the quantified levels to determine response to CRT therapy, wherein a panel of biomarkers includes at least two selected from the group consisting of CRP, SGP-130, sIL-2R, sTNFR-II, IFNg, BNP, sST2, MMP-2, MMP-9, TIMP-1, TIMP-2, TIMP-4. Other embodiments are also included herein. | 09-12-2013 |