Hubbs, US
Charles M. Hubbs, Baton Rouge, LA US
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20100238551 | SURGICAL MICROSCOPE DRAPE LENS FOR REDUCING GLARE - A lens drape for a surgical microscope includes a drape and a lens assembly attached to the drape. The lens assembly includes a drape ring and a lens ring holding a lens. The drape is attached to the drape ring. The lens ring holds the lens at an acute angle. The lens ring is also rotatable on the drape ring. The angle of the lens, and the ability to rotate the lens, allows for reduction of glare during surgery performed using a microscope. | 09-23-2010 |
Charlie Hubbs, Dalton, GA US
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20090047495 | Silicone-impregnated foam product and method for producing same - The present invention relates to products having a foam carrier or substrate, and particularly to such products employing a reticulated polyurethane foam carrier impregnated with silicone polymer. The present invention also relates to a method of producing these silicone-impregnated foam products. | 02-19-2009 |
20110111196 | Silicone-impregnated foam product with fillers and method for producing same - A resilient structure comprising a carrier layer of open-cell, resilient urethane foam material. The foam material is substantially completely and uniformly impregnated with an impregnant comprising silicone. The impregnant is cured after said impregnation to produce a foamed, open cell, resilient structure wherein the open cells thereof partially comprise the carrier layer of urethane foam material and the silicone includes a filler. A method for producing a resilient structure comprising applying silicone onto a carrier layer of open-cell, resilient urethane foam material, substantially completely and uniformly impregnating the carrier layer with the silicone, and curing the silicone to produce a foamed open-cell, resilient structure wherein the open cells thereof partially comprise the foam material, wherein the structure exhibits properties of the silicone, and wherein the silicone includes a filler. | 05-12-2011 |
David Hubbs, Louisville, KY US
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20100146814 | Vibratory Flash Dryer - An apparatus for drying and conveying a material includes a vibratory fluid bed dryer having a perforated drying deck on which material is deposited, said fluid bed dryer including a vibratory drive system capable of imparting a variable angle vibratory force to the deck. A flash dryer is also provided, having a fan and heater for supplying hot air through the fluid bed dryer deck and a cyclone for collecting finished, dried material particles. | 06-17-2010 |
Dennis Hubbs, Washington, DC US
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20120185392 | METHOD AND APPARATUS FOR DONATING MONEY TO A CANDIDATE OR ORGANIZATION - A method of donating money to a political candidate or organization using a credit card, and a system of networked computers, comprising: using a credit card to make a purchase, transferring purchase amount information and purchaser information electronically to a central computer | 07-19-2012 |
Gerald Hubbs, Louisville, KY US
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20110004287 | Bifurcated Stent and Delivery System - Systems for delivering a bifurcated stent to a bifurcation site comprise catheters and/or bifurcated stents delivered therefrom. | 01-06-2011 |
Gerald M. Hubbs, Louisville, KY US
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20110137310 | RF ABLATION PROBES WITH TINE VALVES - A tissue ablation probe is provided. The tissue ablation probe comprises an elongated shaft, at least one electrode tine carried by the elongated shaft, at least one tine exit from which the electrode tine(s) can be deployed from the elongated shaft and retracted within the elongated shaft, and a sheath covering the electrode tine exit(s). The sheath may, e.g., line an exterior surface of the elongated shaft or an interior surface of the elongated shaft. The sheath has at least one tine valve (e.g., a slit) positioned over the electrode tine exit(s) and configured to open when the electrode tine is deployed and to close when the electrode tine(s) is retracted. In one embodiment, the tine valve(s) is configured to open in response to pressure exerted during deployment of the electrode tine(s). In another embodiment, the tine valve(s) is configured to hinder the entry of biological material within the elongated shaft. In one embodiment, the sheath is pliable, such that the tine valve(s) can more easily hinder the entry of the biological material. | 06-09-2011 |
20130289553 | RF ABLATION PROBES WITH TINE VALVES - A tissue ablation probe is provided. The tissue ablation probe comprises an elongated shaft, at least one electrode tine carried by the elongated shaft, at least one tine exit from which the electrode tine(s) can be deployed from the elongated shaft and retracted within the elongated shaft, and a sheath covering the electrode tine exit(s). | 10-31-2013 |
Gerald M. Hubbs, Bloomington, IN US
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20080255553 | RADIOFREQUENCY ABLATION DEVICE - A RF ablation device includes a probe assembly that has an elongate cannula having a lumen disposed interiorly of an external wall of the cannula. The elongate cannula includes a plurality of slots formed within the external wall that provide access to the lumen. The probe assembly includes an electrode member that is slidably disposed within the elongate cannula, the electrode member including a plurality of tines configured for passage through the plurality of slots. The slots are disposed in a staggered arrangement or pattern about the external wall of the cannula. The staggered arrangement of slots may be used in a monopolar or bipolar arrangement of the electrodes on the cannula. A bipolar arrangement of electrodes using the staggered configuration produces larger ablation areas in a shorter period of time as compared to prior designs. | 10-16-2008 |
20120271296 | RADIOFREQUENCY ABLATION DEVICE - A RF ablation device includes a probe assembly that has an elongate cannula having a lumen disposed interiorly of an external wall of the cannula. The elongate cannula includes a plurality of slots formed within the external wall that provide access to the lumen. The probe assembly includes an electrode member that is slidably disposed within the elongate cannula, the electrode member including a plurality of tines configured for passage through the plurality of slots. The slots are disposed in a staggered arrangement or pattern about the external wall of the cannula. The staggered arrangement of slots may be used in a monopolar or bipolar arrangement of the electrodes on the cannula. A bipolar arrangement of electrodes using the staggered configuration produces larger ablation areas in a shorter period of time as compared to prior designs. | 10-25-2012 |
Irma Hubbs, Port Orange, FL US
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20100259915 | Window light box with blind - A window light box with blind. A light source within the light box provides light through a front aperture. A blind is mounted to a light box front, and is extendable over the front aperture. The blind and/or light source may be colored; the blind may be opaque, translucent, or transparent. The light source is electrically connected to a power source through a switch, which may be an ON/OFF dimmer switch. An alternate embodiment is disclosed wherein the light source is electrically connected to a power source through a switching receiver, and a remote controls the receiver. A battery back-up is disclosed to power the light source in the event of power source interruption. The light source may be fluorescent, incandescent, serpentine lighting, a Christmas light string, LED, or other appropriate light source. | 10-14-2010 |
Jed Hubbs, Cambridge, MA US
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20100010041 | DIFLUORINATED PIPERIDINES FOR TREATMENT OF ALZHEIMER'S DISEASE AND RELATED CONDITIONS - Compounds of formula (I). Selectively inhibit production of Aβ(1-42) and hence find use in treatment of diseases associated with deposition of β-amyloid in the brain. | 01-14-2010 |
20100093665 | SILYLATED PIPERIDINE DERIVATIVES - Compounds of formula I: I wherein at least one of R4 and R5 comprises Si(R6)3 as a substituent selectively attenuate production of Aβ(1-42) and hence find use in treatment of Alzheimer's disease and related conditions. | 04-15-2010 |
20110275719 | NOVEL TRIFLUOROMETHYLSULFONAMIDE GAMMA SECRETASE INHIBITOR - The present invention is directed to a novel trifluoromethylsulfonamide derivative which inhibits the processing of APP by the putative γ-secretase and thus is useful in the treatment or prevention of Alzheimer's disease. This compound possesses favorable pharmacokinetic properties in higher species (rhesus) and thus can be dosed on an intermittent dosing regiment (e.g., once weekly). When dosed on such a regiment the compound exhibits significant and continuous Aβ lowering without the manifestation of Notch associated gastrointestinal toxicity for extended periods, e.g., 7 days. Pharmaceutical compositions and methods of use are also included. | 11-10-2011 |
Jed L. Hubbs, Cambridge, MA US
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20090069250 | Inhibitors of Histone Deacetylase - The present invention relates to a novel class of compounds. These compounds can inhibit histone deacetylase and are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and/or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The compounds of the invention may also be useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and/or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases. The present invention further provides pharmaceutical compositions comprising the compounds of the instant invention and sale dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of these compounds in vivo. | 03-12-2009 |
20100048623 | PIPERIDINES AND RELATED COMPOUNDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE - Compounds of formula (I) are modulators of gamma-secretase, and hence are useful in treatment of Alzheimer's disease. | 02-25-2010 |
Jed Lee Hubbs, Cambridge, MA US
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20090069391 | Benzothiophene hydroxamic acid derivatives - The present invention relates to a novel class of hydroxamic acid derivatives. The hydroxamic acid compounds can be used to treat cancer. The hydroxamic acid compounds can also inhibit histone deacetylase and are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and/or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The compounds of the invention are also useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and/or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases. The present invention further provides pharmaceutical compositions comprising the hydroxamic acid derivatives and safe dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of the hydroxamic acid derivatives in vivo. | 03-12-2009 |
20090082308 | Benzothiophene derivatives - The present invention relates to a novel class of benzothiophene amide derivatives. The hydroxamic acid compounds can be used to treat cancer. The benzothiophene amide compounds can also inhibit histone deacetylase and are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and/or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The compounds of the invention may also be useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and/or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases. The present invention further provides pharmaceutical compositions comprising the hydroxamic acid derivatives and safe dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of the hydroxamic acid derivatives in vivo. | 03-26-2009 |
20110251379 | COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS - As described herein, the present invention provides compounds useful for treating or lessening the severity of a neurodegenerative disorder. The present invention also provides methods of treating or lessening the severity of such disorders wherein said method comprises administering to a patient a compound of the present invention, or composition thereof. Said method is useful for treating or lessening the severity of, for example, Alzheimer's disease. | 10-13-2011 |
20130060013 | Compounds useful for treating neurodegenerative disorders - The present invention provides compounds of formula I: | 03-07-2013 |
20130060019 | Compounds for Use in Treating Neurodegenerative Disorders, Synthesis Thereof, and Intermediates Thereto - The present invention provides methods of making a compound of formula II: | 03-07-2013 |
20130060020 | Compounds useful for treating neurodegenerative disorders - The present invention provides compounds of formula I: | 03-07-2013 |
20130060021 | Compounds useful for treating neurodegenerative disorders - The present invention provides compounds of formula I: | 03-07-2013 |
20130060022 | Compounds useful for treating neurodegenerative disorders - The present invention provides compounds of formula I: | 03-07-2013 |
20130060023 | Compounds useful for treating neurodegenerative disorders - The present invention provides compounds of formula I: | 03-07-2013 |
20130060024 | Compounds useful for treating neurodegenerative disorders - The present invention provides compounds of formula I: | 03-07-2013 |
Jonathan W. Hubbs, Phoenix, AZ US
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20090317195 | SOIL CONDITIONER - Disclosed are soil conditioning products comprising: (1) one or more of an oil, a polymeric binder, a wax and a gel, or (2) a carrier and one or more of an oil, a polymeric binder, a wax and a gel. The wax is preferably a soy wax and the oil is preferably a soy oil. The invention further includes surface materials comprising a soil and a soil conditioning product according to the invention. Other materials may be added to any of these soil conditioning products or surface materials. If a carrier is used the soil conditioning product may be added to soil as a granular material, rather than as a gel or liquid. | 12-24-2009 |
20100088957 | NATURAL TURF WITH BINDER - A playing surface according to the invention includes turf, sand, fibers and organic binder, wherein the playing surface may be harvested in rolls. A field including the playing surface may have a sand base layer. | 04-15-2010 |
20140274821 | REINFORCED HYDRAULIC FRACTURING FLUID PROPPANT AND METHOD - Composite mixtures are disclosed that include: (a) proppant, and (b) fibers, and/or (c) one or more of an organic binder, wax, gel, oil or polymeric binder. A method for improving the engineering properties of proppants includes adding one or more of the materials to the proppant, and mixing them for incorporation into a hydraulic fluid (such as water). Alternatively, the proppants, and/or fibers and/or other constituents may be added separately to a hydraulic fluid such as water. | 09-18-2014 |
Jonathon W. Hubbs, Phoenix, AZ US
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20100216639 | GYPSUM SOIL CONDITIONER - Soil conditioning products according to the invention preferably include gypsum and organic binder. One or more of an oil, a polymeric binder, a gel, fibers and wax could also be included. The invention further includes surface materials comprising a soil and a soil conditioning product according to the invention. Other materials may be added to any of these soil conditioning products or surface materials. | 08-26-2010 |
Michael E. Hubbs, Berlin Center, OH US
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20100193665 | MOLD TOP INSULATING ASSEMBLY AND METHOD OF USE - An ingot mold top comprising a base having a pair of side walls, each side wall having a first end and a second end, each of the first ends terminating in an angled portion and the second ends connected by a first end wall, a wedge having an end wall and a pair of side walls, the pair of side walls extending generally perpendicularly away from the end wall, and wherein the wedge pair of side walls each terminate in an angled portion and the base and wedge completely encompass an interior periphery of a mold. | 08-05-2010 |
Ralph Hubbs, Brooklyn, MI US
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20080308168 | COMPACT HYDRAULIC ACCUMULATOR - A lightweight, optimally efficient, easily serviced, piston-in-sleeve high pressure accumulator is provided. The accumulator includes one or more cylindrical composite pressure vessel separate end cap manifolds. A piston slidably disposed in a thin impermeable internal sleeve in the accumulator separates two chambers, one adapted for containing a working fluid and the other adapted for containing gas under pressure. Gas is provided in a volume between the impermeable internal sleeve and the composite pressure vessel wall. Additional gas is optionally provided in gas cylinders. Further components are provided for withstanding harmful effects of radial flexing of the composite vessel wall under high pressures, and from stresses present in use in mobile applications such as with a hydraulic power system for a hydraulic hybrid motor vehicle. | 12-18-2008 |
William O. Hubbs, Cedar Hill, MO US
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20110235143 | Precision scan sphere - A precision scan sphere designed for use in conjunction with scanner technology, and includes a full or partial sphere, having a laser detecting surface, and which can be mounted by a shank into a holder, or held by a steel insert that may be applied to a sphere mount, during its application and usage. Because of the reduction and size of the insert, as applied to the bottom of the scan sphere, as an example, a 2.375 inch diameter sphere can mount directly to a 1.5 inch sphere mount, during its application and usage. | 09-29-2011 |
20110284384 | Electroformed cornercube retroreflector - An electroformed cornercube retroreflector, wherein a conductive mandrel locates within an electrolyte containing metallic solution and through charging of the mandrel located within the solution attains electrodepositing of the metallic solution on to the mandrel for the purpose of plating a thick coating of the metal upon the mandrel. When the coating has achieved sufficient structural integrity to form a cornercube retroreflector, it is removed from the electrolyte, the deposited metal is separated or stripped from the mandrel to provide a natural highly inner polished metallic cornercube that can be placed within a partial sphere or other supportive body for use as a retroreflector for application for laser tracking in industrial or other applications. | 11-24-2011 |
20120038994 | Universal sphere mount - The universal sphere mount provides a spherically mounted retro-reflector conical nest mount having a base, a body of lesser diameter than the base, and a precise nest in the body that receives a retro-reflector target. The body steps inwardly from the base or has bevel. The body has a lesser diameter than the base so the reflector achieves an orientation below a horizontal plane at any horizontal rotation upon the body. The nest receives a spherically mounted retro-reflector and positions it with high precision over the shank. The nest has at least three oblique clearance areas, equally spaced, that permit a maximum negative acceptance angle for incident light to a mounted spherically mounted retro-reflector without occlusion and at any angle of rotation upon the body. The universal sphere mount achieves tolerances, within 0.0005 inch of the centerline and of the height of a spherically mounted retro reflector placed therein. | 02-16-2012 |