Sophia
Sophia Bethani, Athens GR
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20100144949 | Synthetic aggregates comprising sewage sludge and other waste materials and methods for producing such aggregates - In one example of an embodiment of the invention, a method for producing an aggregate is disclosed comprising mixing sewage sludge from a waste water treatment facility with a non-coal combustion ash silicoaluminous waste material, agglomerating the mixture to form an agglomerate, and pyroprocessing the agglomerate to form an aggregate. The waste material may comprise municipal solid waste incinerator bottom ash, incinerator fly ash, incinerator filter dusts, cement kiln dusts, waste glass, blast furnace slag, kiln dusts, and/or granite sawing residues, for example. The method may further comprise milling the waste material prior to mixing. Preferably, the milling is wet milling. Pyroprocessing of the agglomerate may take place in a rotary kiln. The resulting aggregate may be a lightweight or a normal weight, sintered or vitrified aggregate. Aggregates and methods for making aggregates of high and low calcium silicoaluminous materials are also disclosed. | 06-10-2010 |
20100319581 | Pyroprocessed aggregates comprising IBA and low calcium silicoaluminous materials and methods for producing such aggregates - In accordance with an embodiment, a method for producing an aggregate is disclosed comprising mixing IBA and a second, silicoaluminous material having a calcium content less than the IBA. The method further comprises agglomerating the mixture, such as by pelletizing, and pyroprocessing the agglomerates, such as by sintering or vitrification, to form the aggregate. The second material may be a clay, such as bentonite or kaolin, a mining waste, such as granite sawing residues, waste glass, or furnace bottom ash, for example. The addition of the second material has been found to facilitate production of lightweight and normal weight aggregates. Preferably, the IBA or the mixture of IBA and the second material are wet milled prior to agglomeration. Methods for producing expanded aggregates are also disclosed. | 12-23-2010 |
Sophia Chen, Taoyuan Hsien TW
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20120250247 | MULTI-CASE RACK FOR INDUSTRIAL COMPUTER - A multi-case rack for an industrial computer includes a rack body and a plurality of removable cases. The removable case can be installed with either its axial end positioned ahead, thus compatible to both a front circuit board and a rear circuit board. The removable case has an anti-shock HD mount capable of holding either two 2.5″ hard drives or one 3.5″ hard drive. The removable case allows heat-dissipating fans to be installed and positioned in a screw-free, hot-swap manner. The removable cases can be readily installed into or from a rack body. | 10-04-2012 |
Sophia Chen, Luchu Shiang TW
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20120252344 | HEAT-DISSIPATING DUAL-SYSTEM RACKMOUNT FOR 1U INDUSTRIAL COMPUTER - A heat-dissipating dual-system rackmount for a 1U industrial computer includes a removable rackmount and two removable computer cases. The rackmount features that two lateral plates of the removable computer case are formed with vents for heat dissipation, and that two laterals and a partition of the rackmount are formed with air channels, along which air channels air vents are formed corresponding to the vents for heat dissipation of the removable computer case, thereby improving ventilation among the heat-generating components in the removable computer case and in turn providing good heat-dissipation effects. | 10-04-2012 |
Sophia Christou-Kelly, Scarborough CA
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20100050315 | HOSPITAL GARMENT - An improved hospital garment is disclosed for use by a patient. The garment may be a shirt-like portion having a placket to permit the shirt-like portion to be donned and doffed in the manner of a robe, and defining a neck opening through which the neck of the patient extends when the shirt-like portion is operatively disposed on the patient. The garment may include sleeves through which the arms of the patient extend when the shirt-like portion is operatively disposed on the patient. Each sleeve may be defined by a piece of fabric and may have a hook and loop fastener secured thereto. On each sleeve, the fabric piece, when the shirt-like portion is operatively disposed upon the patient and the patient is upright, overlaps upon and may be secured by the hook and loop fastener to itself upon the shoulder of the patient. This fastener may be releasable to permit the shirt-like portion to be parted along each sleeve to the neck opening to provide ready access to the upper torso of the patient. It may be shaped and dimensioned such that the overlapped part of the fabric piece substantially overhangs the shoulder so as to be capable of suspending the shirt-like portion from the shoulder when the overlapping and overlapped portions are released from one another by the fastener. | 03-04-2010 |
Sophia Cui, San Francisco, CA US
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20150161554 | INTELLIGENT DISPATCH SYSTEM FOR SELECTING SERVICE PROVIDERS - A system and method for arranging a transport service is described. A server can receive a request for transport from a computing device of a first user. The request can include information about a pickup location of the first user. In response to receiving the request, the server can determine a plurality of drivers that are capable of providing transport for the first user by determining a first set of drivers that are each driving a vehicle that is unoccupied by other users, and determining a second set of drivers that are each providing transport service to one or more other users to a respective destination location that is within a threshold distance or threshold estimated travel time from the pickup location of the first user. The server can select a first driver from the plurality of drivers to provide the transport service for the first user. | 06-11-2015 |
20150161564 | SYSTEM AND METHOD FOR OPTIMIZING SELECTION OF DRIVERS FOR TRANSPORT REQUESTS - A computing system operates to process multiple transport requests at one time, each of the multiple transport request specifying a pickup location that is within a geographic region. During a given interval when each of the multiple transport request are open, a pool of candidate drivers is determined within the geographic region that can fulfill one or more of the transport requests within a threshold duration of time. A driver is selected for each of the multiple transport requests. In selecting the driver, the computer system implements an optimization process to minimize an estimated time to pick up for at least one of the multiple transport requests | 06-11-2015 |
20160034828 | DETERMINING AND PROVIDING PREDETERMINED LOCATION DATA POINTS TO SERVICE PROVIDERS - A system and method for arranging a transport service is described. A system can receive a request for transport service from a user device. The request can include a requested pickup location data point. The system determines a predetermined location data point associated with the requested pickup location data point. The first predetermined location data point can be different from the requested pickup location data point. The system selects a driver to perform a transport service for the user based, at least in part, on the requested pickup location data point, and transmits the predetermined location data point to a driver device of the selected driver. | 02-04-2016 |
Sophia Djebali, Lyon FR
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20150309048 | METHODS AND KITS FOR DETECTING ANTIGEN-INDUCED MEMORY CD8+ T CELLS - The present invention relates to methods and kits for detecting antigen-induced memory CD8+ T cells. In particular, the invention relates to a method for determining the presence of a population of antigen-induced memory CD8+ T cells in a sample, comprising i) isolating the population of the CD8+ T cells from the sample and ii) detecting in said population the expression of CCL5 or NKG2D and iii) concluding that at least one population of antigen-induced memory CD8+ T cells is present in a sample when CCL5 or NKG2D is detected as step ii). | 10-29-2015 |
Sophia Fang, Los Angeles, CA US
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20090016075 | SEMICONDUCTOR LIGHTING IN CONSOLE SYSTEM FOR ILLUMINATING BIOLOGICAL TISSUES - The present disclosure is directed to illumination techniques that include the use of one or more sets of Light Emitting Diodes or LEDs as light sources in a console/module system. The LED light sources can be utilized to produce a light beams with a specified/combination of intensity and spectrum. Of course, embodiments according to the present disclosure are not limited to one intensity/spectrum but multiple combinations of intensity and spectrum can be implemented. Such systems/methods can be implemented with various optical elements including filter, lenses, mirrors, and/or optical fibers. The system is controlled by voice activation, touch screen, footswitch or wireless communication. The LEDs might also be pulsed as a driving system. The optical fiber cable is tethered to the control. | 01-15-2009 |
20100157620 | ENHANCED VISUALIZATION ILLUMINATION SYSTEM - A first light source producing a first light beam with a first intensity and a second light source producing a second light beam with a second intensity. A light filter device receives the first light beam and transmits a filtered portion of the first light beam. A first angling device reflects the filtered portion of the first light beam in a first angled direction and a second angling device reflects the second light beam in a second angled direction. A mirror receives and in turn reflects the filtered portion of the first light beam reflected by the first angling device and the second light beam reflected by the second angling device to form a converged light beam with a third intensity. | 06-24-2010 |
20110282161 | ENHANCED VISUALIZATION ILLUMINATION SYSTEM - A first light source producing a first light beam with a first intensity and a second light source producing a second light beam with a second intensity. A light filter device receives the first light beam and transmits a filtered portion of the first light beam. A first angling device reflects the filtered portion of the first light beam in a first angled direction and a second angling device reflects the second light beam in a second angled direction. A mirror receives and in turn reflects the filtered portion of the first light beam reflected by the first angling device and the second light beam reflected by the second angling device to form a converged light beam with a third intensity. | 11-17-2011 |
Sophia Frij, Maale Adumim IL
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20150253845 | SYSTEM AND METHOD FOR ALTERING A PERSPECTIVE OF A FIGURE PRESENTED ON AN ELECTRONIC DISPLAY - A method for altering a position of an object in an image on a display screen in response to a position of a viewer of such screen. For example, an image of a person that is displayed on a screen may be altered to face or be directed towards a viewer of the screen that is detected by for example a sensor, so that the image of the person on the screen appears to look at the viewer who is looking at the screen. | 09-10-2015 |
20150346818 | SYSTEM AND METHOD FOR DETECTING MICRO EYE MOVEMENTS IN A TWO DIMENSIONAL IMAGE CAPTURED WITH A MOBILE DEVICE - A system and method for using a mobile device to capture an image of eyes of a person and calculate a location or coordinates of one or each of the irises in a first frame and a location or coordinate of the same iris in a later frame. A vector may be calculated between the location or coordinate of a first iris in a first frame and a location or coordinate of the first iris in a second frame. A second eye vector may be calculated between the location or coordinate of a second iris in a first frame and such second iris in a second frame. An angle between the first iris vector and the second iris vector may be calculated. Such angle may be used as an indication of a physiological problem. | 12-03-2015 |
Sophia Hober, Stockholm SE
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20100022760 | MUTANT PROTEIN - The present invention relates to an immunoglobulin-binding protein, wherein at least one asparagine residue has been mutated to an amino acid other than glutamine or aspartic acid, which mutation confers an increased chemical stability at pH-values of up to about 13-14 compared to the parental molecule. The protein can for example be derived from a protein capable of binding to other regions of the immunoglobulin molecule than the complementarity determining regions (CDR), such as protein A, and preferably the B-domain of Staphylococcal protein A. The invention also relates to a matrix for affinity separation, which comprises an immunoglobulin-binding protein as ligand coupled to a solid support, in which protein ligand at least one asparagine residue has been mutated to an amino acid other than glutamine. | 01-28-2010 |
20110112276 | MUTATED IMMUNOGLOBULIN-BINDING PROTEIN - The present invention relates to an immunoglobulin-binding protein, wherein at least one asparagine residue has been mutated to an amino acid other than glutamine or aspartic acid, which mutation confers an increased chemical stability at pH-values of up to about 13-14 compared to the parental molecule. The protein can for example be derived from a protein capable of binding to other regions of the immunoglobulin molecule than the complementarity determining regions (CDR), such as protein A, and preferably the B-domain of Staphylococcal protein A. The invention also relates to a matrix for affinity separation, which comprises an immunoglobulin-binding protein as ligand coupled to a solid support, in which protein ligand at least one asparagine residue has been mutated to an amino acid other than glutamine. | 05-12-2011 |
20120238724 | MUTATED IMMUNOGLOBULIN-BINDING PROTEIN - The present invention relates to an immunoglobulin-binding protein, wherein at least one asparagine residue has been mutated to an amino acid other than glutamine or aspartic acid, which mutation confers an increased chemical stability at pH-values of up to about 13-14 compared to the parental molecule. The protein can for example be derived from a protein capable of binding to other regions of the immunoglobulin molecule than the complementarity determining regions (CDR), such as protein A, and preferably the B-domain of Staphylococcal protein A. The invention also relates to a matrix for affinity separation, which comprises an immunoglobulin-binding protein as ligand coupled to a solid support, in which protein ligand at least one asparagine residue has been mutated to an amino acid other than glutamine. | 09-20-2012 |
20130184438 | MUTANT PROTEIN - The present invention relates to an immunoglobulin-binding protein, wherein at least one asparagine residue has been mutated to an amino acid other than glutamine or aspartic acid, which mutation confers an increased chemical stability at pH-values of up to about 13-14 compared to the parental molecule. The protein can for example be derived from a protein capable of binding to other regions of the immunoglobulin molecule than the complementarity determining regions (CDR), such as protein A, and preferably the B-domain of Staphylococcal protein A. The invention also relates to a matrix for affinity separation, which comprises an immunoglobulin-binding protein as ligand coupled to a solid support, in which protein ligand at least one asparagine residue has been mutated to an amino acid other than glutamine. | 07-18-2013 |
20130184442 | METHOD FOR LABELING OF COMPOUNDS - The present invention relates to site-specific labeling of antibodies or fragments thereof with one or more reporter group(s) in a way that does not affect antigen binding. The method for labeling antibodies and/or fragments thereof, comprises the following steps a) providing an IgG binding protein, which comprises α-helix structures, with a photoactivatable group and at least one label; b) forming a mixture of said IgG binding protein and the antibodies and/or fragments to be labeled; and c) UV illuminating said mixture for site-specific labeling of said antibodies and/or fragments thereof. The IgG binding protein is preferably the Z domain of Protein A. | 07-18-2013 |
Sophia Hohlbach, Santa Barbara, CA US
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20150301080 | Automated Atomic Force Microscope and the Operation Thereof - Improvements for rapidly calibrating and automatically operating a scanning probe microscope are disclosed. A central component of the SPM is the force transducer, typically a consumable cantilever element. By automatically calibrating transducer characteristics along with other instrumental parameters, scanning parameters can be rapidly and easily optimized, resulting in high-throughput, repeatable and accurate measurements. In contrast to dynamic optimization schemes, this can be accomplished before the surface is contacted, avoiding tip or sample damage from the beginning of the measurement process. | 10-22-2015 |
Sophia Ilyina, Novosibirsk RU
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20130066560 | APPARATUS AND METHOD FOR ESTIMATING GEOLOGIC BOUNDARIES - A method of estimating a geology of an earth formation includes: receiving gravity measurements from each of a plurality of gravity sensors n | 03-14-2013 |
Sophia Kao, Taichung TW
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20160121113 | Diabetes glucagon mitigation system and method with an electrical energy wave generator - A system and method for relieving high blood sugar factor of diabetes includes an electric energy wave generator with a frequency effect level control formulation. The frequency effect level control formulation includes a control of a single frequency effect level and a control of a multi-frequency modulation effect level and controls and emits a single frequency electric energy wave to a diabetic patient's body in the single frequency effect level according to the frequency effect level control formulation and controls and emits a multi-frequency electric energy wave in a multi-frequency modulation effect level, so as to reduce and eliminate a high blood sugar factor of the diabetic patient's body by the electric energy wave. | 05-05-2016 |
Sophia Karagiannis, London GB
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20140322246 | IGE ANTI-HMW-MAA Antibody - In one aspect, there is provided an antibody or a functional fragment thereof, wherein the antibody or functional fragment thereof is capable of binding specifically to high molecular weight melanoma associated antigen (HMW-MAA), and binding to an Fcε receptor. | 10-30-2014 |
Sophia Khom, Wien AT
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20120022283 | METHODS FOR MAKING VALERENIC ACID DERIVATIVES AND THEIR USE - The present invention is directed to compounds, intermediates and methods for making valerenic acid and its derivatives as well as the use of such compounds as GABA | 01-26-2012 |
20150045574 | METHODS FOR MAKING VALERENIC ACID DERIVATIVES AND THEIR USE - The present invention is directed to compounds, intermediates and methods for making valerenic acid and its derivatives as well as the use of such compounds as GABA | 02-12-2015 |
Sophia Krasikov, Katonah, NY US
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20080235080 | Performance Prediction Service Using Business-Process Information - Performance prediction techniques are provided that utilize business-process information such as transaction history and log information. For example, in one aspect of the invention, a computer-based technique for providing a performance prediction service comprises the following steps/operations. First, business-process information associated with a business is obtained. Then, a performance estimation function is generated based at least in part on the business-process information, the performance estimation function being usable in responding to a query obtained from a potential customer of the business. | 09-25-2008 |
20090006615 | METHOD AND APPARATUS FOR EXTRACTING AND VISUALIZING EXECUTION PATTERNS FROM WEB SERVICES - One embodiment of the present method and apparatus for extracting and visualizing execution patterns from Web Services collects data relating to one or more transactions executed in accordance with one or more Web Services-based applications (e.g., messaging systems or other services). One or more patterns is then extracted from the collected data, where the patterns are representative transactions commonly executed in accordance with the Web Services configuration under analysis. | 01-01-2009 |
20110106944 | METHOD AND APPARATUS FOR EXTRACTING AND VISUALIZING EXECUTION PATTERNS FROM WEB SERVICES - One embodiment of the present method and apparatus for extracting and visualizing execution patterns from Web Services collects data relating to one or more transactions executed in accordance with one or more Web Services-based applications (e.g., messaging systems or other services). One or more patterns is then extracted from the collected data, where the patterns are representative transactions commonly executed in accordance with the Web Services configuration under analysis. | 05-05-2011 |
20110173132 | Method and System For Spawning Smaller Views From a Larger View - A method includes defining a first component set of one or more first components; defining a second component set of one or more second components; and defining an original set of relationships, each relationship being between one component of the first component set and one component of the second component set. The method further includes decomposing the original set of relationships into a collection of view sets, each view set having at least one subset of the original set of relationships where the first and second components are associated with the respective relationships of the subset, and each view set satisfies a set of constraints. The components may be elements of a business model. | 07-14-2011 |
20110302494 | Smart Presentation Application - Disclosed is a computer-implemented method to create a presentation having at least one sheet, where each sheet contains one or more visual elements, as well as a system and computer program embodied on a computer-readable storage medium. The method includes, in response to input from a user, representing visual elements as depictions in a model, where each depiction depicts a single item in the model, where each item is a unit of information with a unique identifier, where each item can be depicted by at least one depiction and each depiction defines the visual representation of the item's information via the visual element. The method further includes, in response to a change to an item made by altering the visual element associated with the depiction of the item, automatically propagating the change to the item to all other depictions of the item across all sheets of the presentation. The method further includes updating the associated visual elements to reflect the change to the item. | 12-08-2011 |
20130069967 | Methods And Apparatus For Creating A Visual Language For Diagrams - Improved systems and techniques for representation of information. As a user creates a graphic design, properties represented by graphical elements of the design, are associated with visual characteristics of the elements, and a palette of elements is made available for use in development of the design or creation of new designs. As generalized elements are added to a design, the generalized elements may take on visual characteristics associated with properties identified by the positioning of the generalized elements in the design. Ongoing or existing designs may be surveyed to identify elements, properties represented by the elements, and visual characteristics associated with the properties, and new elements added to the palette or existing elements modified as a result of one or more surveys. | 03-21-2013 |
20130262166 | METHOD AND SYSTEM FOR SPAWNING SMALLER VIEWS FROM A LARGER VIEW - A method includes defining a first component set of one or more first components; defining a second component set of one or more second components; and defining an original set of relationships, each relationship being between one component of the first component set and one component of the second component set. The method further includes decomposing the original set of relationships into a collection of view sets, each view set having at least one subset of the original set of relationships where the first and second components are associated with the respective relationships of the subset, and each view set satisfies a set of constraints. The components may be elements of a business model. | 10-03-2013 |
20140052757 | TECHNIQUES PROVIDING A SOFTWARE FITTING ASSESSMENT - Techniques are presented for providing a software fitting assessment. The techniques may be performed by methods, apparatus, and/or computer program products. The techniques include automatically matching on a computer system one or more specified requirements for a project with one or more software functions stored in a repository. The automatically matching includes mining the repository in order to match requirements. The repository includes software functions, requirements accumulated from previous projects, and results of stored matches between the software functions and the requirements accumulated from previous projects. The techniques include outputting by the computer system one or more results of the matching. | 02-20-2014 |
20140052758 | Techniques Providing A Software Fitting Assessment - Techniques are presented for providing a software fitting assessment. The techniques may be performed by methods, apparatus, and/or computer program products. The techniques include automatically matching on a computer system one or more specified requirements for a project with one or more software functions stored in a repository. The automatically matching includes mining the repository in order to match requirements. The repository includes software functions, requirements accumulated from previous projects, and results of stored matches between the software functions and the requirements accumulated from previous projects. The techniques include outputting by the computer system one or more results of the matching. | 02-20-2014 |
20140358635 | MAKING PRODUCT SUBSTITUTION RECOMMENDATIONS - Aspects of the invention provide a method for making a product substitution recommendation to a consumer. Initially, a rejection of the product by the consumer is detected. The rejection comprises a failure to purchase a product after the product is added to an online shopping cart, or a return of a product after the product is purchased. Subsequently, a reason for the rejection is determined. A recommendation for a substitute product is then formulated at least in part based on the determined reason for the rejection. Lastly, the recommendation for the substitute product is presented to the consumer. | 12-04-2014 |
20150095183 | Methods and Apparatus for Generating Recommendations - Systems and techniques for generating recommendations for items likely to be of interest to a user. Upon an indication that a recommendation may be needed by a user, a plurality of recommendations from different sources are generated and combined. Suitably, each recommendation includes parameters such as accuracy and confidence parameters. Combining the recommendations comprises adjusting the parameters based on a set of rules established by an operator of a system for combining recommendations. The rules may be adjusted by operator inputs through an interface and may be adjusted, if desired, during generation of a recommendation. At least one of the recommendation sources generates recommendations based on social grouping, wherein social groupings are identified based on connections between members and similarity of purchased between members, and wherein a recommendation for a specific user is generated by identifying groups to which the user belongs and items popular within such groups. | 04-02-2015 |
Sophia Lee, Waltham, MA US
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20140322164 | METHOD OF ASSESSING RISK OF PML - The invention relates to methods of assessing a patient's risk of developing Progressive multifocal leukoencephalopathy (PML). | 10-30-2014 |
20150220693 | DISEASE PROGRESSION PARAMETERS AND USES THEREOF FOR EVALUATING MULTIPLE SCLEROSIS - Methods, systems and kits to detect and/or quantify disease progression in a subject having a progressive form of MS are disclosed. | 08-06-2015 |
20160116483 | METHOD OF ASSESSING RISK OF PML - The invention relates to methods of assessing a patient's risk of developing Progressive multifocal leukoencephalopathy (PML). | 04-28-2016 |
Sophia Lin, Rowland Heights, CA US
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20120202702 | DETECTION OF LOW CONCENTRATION BIOLOGICAL AGENTS - Provided are methods of preparing a sample for detection by placing the sample on a shrinkable scaffold and then shrinking the scaffold. An exemplary shrinkable scaffold is a thermoplastic substrate. | 08-09-2012 |
Sophia Marnell, Alexandria, VA US
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20160104260 | Practitioner Career Management Assessment Interviewer Method and Tool - The practitioner career assessment is a method and device for providing career development and advancement management within hiring organizations. The method includes the steps of consolidating all of a user's career experiences, knowledge, skills and abilities, and automating career guidance and a career pathway roadmap of the user's career development and advancement. As a result, the assessment is operated by a hiring organization, under the complete control of the user, and conducted in a confidential manner, free of any judgment prejudice, and devoid of known and unknown biases associated with human factor or supervisory factors to provide guidance and create a career pathway roadmap to goals and advancement. The device includes a number of modules including a system access, user homepage, user profile or census, core and optional goal assessments, assessment generation, guidance, outreach, reporting, and requirements traceability matrix (RTM) modules. | 04-14-2016 |
Sophia Millington-Ward, Glasnevin IE
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20090197336 | SUPPRESSION OF POLYMORPHIC ALLELES - Methods and agents for suppressing expression of a mutant allele of a gene having a polymorphism are provided. The methods of the invention provide suppression effectors such as antisense nucleic acids or ribozymes, that bind to nucleic acid regions having a polymorphism within a gene such that one allele of a gene is exclusively or preferentially suppressed. The method also provides the administration of a replacement nucleic acid, if required. The invention has the advantage that the same suppression strategy, when directed to polymorphisms, could be used to suppress, in principle, many mutations in a polymorphic gene. This is particularly relevant when large numbers of mutations within a single gene cause disease pathology. | 08-06-2009 |
Sophia Millington-Ward, Dublin 9 IE
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20100190841 | GENETIC SUPPRESSION AND REPLACEMENT - The invention relates to gene suppression and replacement. In particular, the invention relates to enhanced expression of suppression agents for suppressing gene expression in a cell and in vivo and replacement nucleic acids that are not inhibited by the suppression agent. Regulatory elements are included in expression vectors to optimize expression of the suppression agent and/or replacement nucleic acid. | 07-29-2010 |
20120278912 | GENETIC SUPPRESSION AND REPLACEMENT - The invention relates to gene suppression and replacement. In particular, the invention relates to enhanced expression of suppression agents for suppressing gene expression in a cell and in vivo and replacement nucleic acids that are not inhibited by the suppression agent. Regulatory elements are included in expression vectors to optimize expression of the suppression agent and/or replacement nucleic acid. | 11-01-2012 |
Sophia Millington-Ward, Dublin IE
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20150099798 | VARIANTS OF YEAST NDI1 GENE, AND USES THEREOF IN THE TREATMENT OF DISEASE ASSOCIATED WITH MITOCHONDRIAL DYSFUNCTION - An isolated nucleic acid sequence encoding the yeast NDI1 protein of SEQ ID NO: 542 or a functional variant thereof is described. The nucleic acid sequence comprises at least 50 codons which are codon optimised compared with the sequence of yeast NDI1 gene of SEQ ID NO: 1. | 04-09-2015 |
Sophia Pombrik, Bethel, CT US
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20110171382 | SOURCE REAGENT COMPOSITIONS AND METHOD FOR FORMING METAL FILMS ON A SUBSTRATE BY CHEMICAL VAPOR DEPOSITION - A metalorganic complex composition comprising a metalorganic complex selected from the group consisting of: metalorganic complexes comprising one or more metal central atoms coordinated to one or more monodentate or multidentate organic ligands, and complexed with one or more complexing monodentate or multidentate ligands containing one or more atoms independently selected from the group consisting of atoms of the elements C, N, H, S, O and F; wherein when the number of metal atoms is one and concurrently the number of complexing monodentate or multidentate ligands is one, then the complexing monodentate or multidentate ligand of the metalorganic complex is selected from the group consisting of beta-ketoiminates, beta-diiminates, C | 07-14-2011 |
Sophia Pucik, Los Gatos, CA US
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20140336556 | POSTURE SUPPORT GARMENT - Disclosed is a posture support garment. The posture support garment can be designed to use an elastic tension fabric that provides tension on the left sleeve and right sleeve of the posture support garment. The tension created can pull the back of the left sleeve and the right sleeve inwards towards the middle of the wearer of the posture support garment's back. This, in turn, can cause the wearer's shoulders to be pulled back and upwards, thus stretching the wearer's chest and shoulder muscles while also relieving tension on the wearer's back and neck muscles. This can help reverse the effects of repetitive poor posture as well as the physical pains associated with poor posture. The elastic tension fabric can be concealed beneath a back panel to the posture support garment which allows the elastic tension fabric to stretch and contract without affecting the appearance of the back panel. | 11-13-2014 |
Sophia Sanchez, San Francisco, CA US
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20150066104 | METHOD AND SYSTEM FOR PROVIDING ELECTRICAL STIMULATION TO A USER - A method for providing electrical stimulation to a user as a user performs a set of tasks during a time window, the method comprising: providing an electrical stimulation treatment, characterized by a stimulation parameter and a set of portions, to a brain region of the user in association with the time window; for each task of the set of tasks: receiving a signal stream characterizing a neurological state of the user; from the signal stream, identifying a neurological signature characterizing the neurological state associated with the task; and modulating the electrical stimulation treatment provided to the brain region of the user based upon the neurological signature, wherein modulating comprises delivering a portion of the set of portions of the electrical stimulation treatment to the brain region of the user, while maintaining an aggregate amount of the stimulation parameter of the treatment provided during the time window below a maximum limit. | 03-05-2015 |
Sophia Schedin Weiss US
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20150369825 | Diagnosis of Alzheimer Disease, Cognitive Decline and Dementia - The present embodiments relate to the usage of selected protein-derived glycans as biomarkers for diagnosis of Alzheimer disease, cognitive decline and dementia. | 12-24-2015 |
Sophia Scipio, Sunrise, FL US
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20110005798 | LOCKING MECHANISM FOR A COVER FOR A HOUSING OF AN ELECTRONIC DEVICE - The disclosure relates to a housing for an electronic device. The housing comprises: a back housing defining an interior compartment of the device; a receptacle to receive a first locking feature from a cover for the electronic device; and at least one moveable second locking feature in the receptacle to engage the first locking feature to hold the cover to the back housing. In the back housing the second locking feature is selectively moved from a first engaged position with the first locking feature to a second disengaged position with the first locking feature when a predefined force is applied at a specific location at the back housing or the cover. | 01-13-2011 |
Sophia Tan, Singapore SG
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20130227220 | Data Storage Device and Method of Managing a Cache in a Data Storage Device - A data storage device is provided. The data storage device includes a data storage medium having a plurality of data blocks, a cache having a plurality of cache blocks, wherein each cache block is identified by a cache block address, a cache control memory including a memory element for each data block configured to store the cache block address of the cache block in which data of the data block is written. | 08-29-2013 |
Sophia Teutschler, San Jose, CA US
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20150347748 | METHOD AND APPARATUS FOR HANDLING SECURITY OF AN APPLICATION AND ITS EXTENSION - Techniques for handling security of an application and its extension are described. In one embodiment, an application manager of an operating system running within a data processing system launches an application in a first sandboxed environment based on a first security profile associated with the application. In response to receiving a request from the application for accessing a function of an application extension that is associated with the application, the application manager launches the application extension in a second sandboxed environment based on a second security profile associated with the application extension. The application manager is to individually enforce security and manage resources of the application and the application extension in the first and second sandboxed environments based on the first and second security profiles, respectively. The second security profile specifies resources fewer than the first security profile. | 12-03-2015 |
Sophia Thizon, Gennevilliers Cedex FR
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20150188231 | COMPACT ANTENNA STRUCTURE FOR SATELLITE TELECOMMUNICATIONS - An antenna structure for telecommunications is provided. The antenna structure may be particularly for satellite telecommunications. The antenna structure includes an emitting surface including at least one set of a plurality of elementary emitting antennas forming an array, at least one elementary emitting antenna including two generally circular patches that are at least partially superimposed, the at least one elementary emitting antenna being dimensioned to emit at least one electromagnetic wave having a frequency between 27 gigahertz and 31 GHz. | 07-02-2015 |
Sophia Vrontou, Pasadena, CA US
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20140178305 | IDENTIFICATION AND USE OF ANXIOLYTIC COMPOUNDS - The present disclosure provides methods and compositions that can be used to identify anxiolytic compounds, and to treat anxiety in a subject. Methods and compositions for identifying activating stimuli for sensory neurons, for example MrgprB4 | 06-26-2014 |
Sophia Wang, Xin-Zhu City TW
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20110024879 | METHOD TO REDUCE PRE-ALIGNMENT ERROR USING MULTI-NOTCH PATTERN OR IN COMBINATION WITH FLAT SIDE - A semiconductor wafer has a pre-alignment pattern including two or more notches on the wafer edge and the notches are used for wafer pre-alignment in fabrication processes. In one embodiment, at least two distances along the wafer edge between any adjacent notches are different. In another embodiment, distances along the wafer edge between any adjacent notches are each different. In another aspect, the pre-alignment pattern includes one or more notches on the wafer edge and one flat side on the wafer edge, wherein the notches and the flat side are used for wafer pre-alignment in fabrication processes. In one embodiment, at least two distances along the wafer edge between any adjacent notches or between the flat side and an adjacent notch are different. In another embodiment, distances along the wafer edge between any adjacent notches and between the flat side and an adjacent notch are each different. | 02-03-2011 |
20110024924 | METHOD AND STRUCTURE OF STACKING SCATTEROMETRY-BASED OVERLAY OR CD MARKS FOR MARK FOOTPRINT REDUCTION - The present disclosure provides an integrated circuit. The integrated circuit includes a semiconductor substrate; a plurality of material layers formed on the semiconductor substrate, each of the material layers including a circuit pattern therein; and a plurality of diffraction-based periodic marks formed in the plurality of material layers and stacked in a same region. One of the diffraction-based periodic marks is different from at least one other of the diffraction-based periodic marks in pitch. | 02-03-2011 |
20110115057 | DESIGN STRUCTURE FOR INTEGRATED CIRCUIT ALIGNMENT - A method and device for pattern alignment are disclosed. The device can include an exposure field; a die within the exposure field, wherein the die comprises an integrated circuit region, a seal ring region, and a corner stress relief region; and a die alignment mark disposed between the seal ring region and the corner stress relief region. | 05-19-2011 |
20130201462 | METHOD OF DETERMINING OVERLAY ERROR AND CONTROL SYSTEM FOR DYNAMIC CONTROL OF RETICLE POSITION - A method of determining overlay error. The method includes transferring a pattern from a reticle to a wafer and selecting a first set of data points to measure the positional difference between features on the reticle and features on the wafer. The method also includes determining a second set of data points characteristic of the first set of data points but containing fewer data points. A control system for using the second set of data points to dynamically adjust the position of the reticle. | 08-08-2013 |
Sophia Xu, Wuxi CN
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20130280774 | DIRECT STARCH TO FERMENTABLE SUGAR AS FEEDSTOCK FOR THE PRODUCTION OF ISOPRENE, ISOPRENOID PRECURSOR MOLECULES, AND/OR ISOPRENOIDS - Provided herein are compositions and methods related to the direct conversion of the starch in a ground or fractionated grain into a fermentable sugar feedstock capable of serving as a carbon source for the industrial production of one or more products by a fermenting organism, such as isoprene, isoprenoid precursor molecules, and/or isoprenoids. Such conversions may be performed at temperatures at or below the initial gelatinization temperature of the starch present in the grain and may utilize one or more isolatable endogenous enzymes present in certain unrefined grains. | 10-24-2013 |
Sophia Yang, Half Moon Bay, CA US
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20150161212 | SEARCH RESULT PREVIEWS - Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for presenting information. In one aspect, a method includes receiving search result data representing a search result and extended result content for the search result, where at least a portion of the received extended result content including off-page content that was obtained from a resource that is not referenced by the search result. The search result is presented and a user interaction with a search result is determined to have occurred. In response to determining that the user interaction occurred, a portion of extended result content for the search result is presented. The extended result content can be presented while maintaining presentation of at least a portion of the search result. A size of the search result location in which the extended result content is presented can be expanded to present a larger portion of the extended result content in the expanded search result location | 06-11-2015 |
Sophia Yang, East Hanover, NJ US
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20100108630 | Tray Insert Movable Between Collapsed And Erected Positions - A collapsible insert includes a series of adjacent cells. Each cell may include a support surface capable raised to an elevated position above the bottom of the tray by a pair of legs. Each leg may have a lower portion and an upper portion. The lower portion of each leg extends below the support surface and can rest on the bottom of the tray, and functions to raise the support surface to the elevated position. The upper portion of each leg extends above the support surface and is used to divide each cell and partially constrain food product within a cell while the insert is in the erected position and disposed within a tray. | 05-06-2010 |
Sophia Yang, Arcadia, CA US
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20160089817 | METHOD FOR FABRICATING A SANDWICH BOX IMPACT BEAM - A method for fabricating a sandwich box impact beam for a vehicle. The method includes fabricating inner and outer facing sandwich structures each including an inner facesheet, an outer facesheet and a micro-truss core therebetween. The micro-truss cores are an ordered three-dimensional network of self-propagating polymer waveguides grown from a photo-monomer resin using a controlled exposure to collimated UV light sources at specified orientations through a plurality of apertures in a mask. The method includes mounting the inner and outer sandwich structures so that an open area is provided therebetween where the inner facesheets face each other across the open area. | 03-31-2016 |
20160090056 | HIERARCHICAL SANDWICH STRUCTURES - A hierarchical sandwich box impact beam for a vehicle that includes spaced apart micro-truss sandwich structures defining an open area therebetween. The impact beam includes an outer facing sandwich structure including an outer facesheet, an inner facesheet and a micro-truss core formed therebetween, and an inner facing sandwich structure including an outer facesheet, an inner facesheet and a micro-truss core formed therebetween. One or more structural connecting sections are coupled to the inner and outer facing sandwich structures so as to define the open area between the structures. | 03-31-2016 |
Sophia Yu, Atchison, KS US
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20100261700 | BETA-LACTAMASE INHIBITORS - Broad spectrum beta-lactamase inhibitors. Certain inhibitors also exhibit potent antibiotic activity in addition to beta-lactamase inhibition. Compounds of the invention are designed such that on cleavage of the beta-lactam ring reactive moieties are generated which can inactivate beta-lactamase. Also provided are methods of making beta-lactamase inhibitors and beta-lactam antibiotics exhibiting such inhibition. Additionally provided are pharmaceutical compositions for treatment or prevention of bacterial infections and methods of treatment of such infections. | 10-14-2010 |
20160031906 | Derivatized 3-Styryl-Cephalosporins - Broad spectrum beta-lactamase inhibitors. Certain inhibitors also exhibit potent antibiotic activity in addition to beta-lactamase inhibition. Compounds of the invention are designed such that on cleavage of the beta-lactam ring reactive moieties are generated which can inactivate beta-lactamase. Also provided are methods of making betalactamase inhibitors and beta-lactam antibiotics exhibiting such inhibition. Additionally provided are pharmaceutical compositions for treatment or prevention of bacterial infections and methods of treatment of such infections. | 02-04-2016 |
Sophia Yu, Fairfield, IA US
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20090131394 | BROAD SPECTRUM BETA-LACTAMASE INHIBITORS - Broad spectrum beta-lactamase inhibitors. Certain inhibitors also exhibit potent antibiotic activity in addition to beta-lactamase inhibition. Compounds of the invention are designed such that on cleavage of the beta-lactam ring reactive moieties are generated which can inactivate beta-lactamase. Also provided are methods of making beta-lactamase inhibitors and beta-lactam antibiotics exhibiting such inhibition. Additionally provided are pharmaceutical compositions for treatment or prevention of bacterial infections and methods of treatment of such infections. | 05-21-2009 |
Sophia Zhang, Shanghai CN
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20100004775 | METHOD AND SYSTEM FOR DEFECT DETECTION IN MANUFACTURING INTEGRATED CIRCUITS - Method and system for defect detection in manufacturing integrated circuits. In an embodiment, the invention provides a method for identifying one or more sources for possible causing manufacturing detects in integrated circuits. The method includes a step for providing a plurality of semiconductor substrates. The method includes a step for processing the plurality of semiconductor substrates in a plurality of processing steps using a plurality of processing tools. The method additionally includes a step for providing a database, which includes data associated with the processing of the plurality of semiconductor substrates. The method further includes a step for testing the plurality of semiconductor wafers after the processing of the plurality of semiconductor substrates. Additionally, the method includes a step for detecting at least one defect characteristic associated with the plurality of the semiconductor substrates that have been processed. Moreover, the method includes a step for identifying a set of processing steps. For example, the set of processing step are possibly associated with the defect characteristic. | 01-07-2010 |
Sophia Zhou, Camarillo, CA US
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20100234749 | SYSTEM AND METHOD FOR COMBINING SERIAL ECG ANALYSIS AND ECG ORDERING - A system and method for receiving a request for a test to be performed on a patient, retrieving information about the patient, receiving further information about the test after the test is performed and comparing the information to the further information. In addition, a system having an input device for receiving a request for a test to be performed on a patient and a management system configured to retrieve information corresponding to the patient, combine the received request and the retrieved information into a modified request, and forward the modified request to a device performing the test. | 09-16-2010 |
20110201957 | CARBON DIOXIDE MONITORING SYSTEM - A CO2 monitoring system ( | 08-18-2011 |