Liu, NC
Ben H. Liu, Raleigh, NC US
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20090270274 | BIOCHIPS AND RELATED AUTOMATED ANALYZERS AND METHODS - The present invention provides biochips that include: (a) a plurality of cards, each card having a plurality of card apertures extending therethrough, each respective card aperture having one or more cross sectional areas; and (b) a plurality of gaskets, at least one gasket residing intermediate two neighboring cards, each gasket having a plurality of gasket apertures extending therethrough. At least some of the gasket apertures have an area that is greater than that of at least one adjacent card aperture. Different sets of the gasket apertures and card apertures define a plurality of fluidic flow channels. Also provided herein are methods of making and using biochips. | 10-29-2009 |
20110076783 | MULTI-DIMENSIONAL FLUID SENSORS AND RELATED DETECTORS AND METHODS - The present invention provides multi-dimensional sensors with fluidic flow channels for processing fluid samples. | 03-31-2011 |
20130008806 | FLUID SENSORS AND RELATED DETECTORS AND METHODS - The present invention provides fluidic testing devices with fluidic flow channels for processing fluid samples. | 01-10-2013 |
20130171625 | BIOCHIPS AND RELATED AUTOMATED ANALYZERS AND METHODS - The present invention provides biochips that include: (a) a plurality of cards, each card having a plurality of card apertures extending therethrough, each respective card aperture having one or more cross sectional areas; and (b) a plurality of gaskets, at least one gasket residing intermediate two neighboring cards, each gasket having a plurality of gasket apertures extending therethrough. At least some of the gasket apertures have an area that is greater than that of at least one adjacent card aperture. Different sets of the gasket apertures and card apertures define a plurality of fluidic flow channels. Also provided herein are methods of making and using biochips. | 07-04-2013 |
20140248616 | METHODS OF MONITORING FLUID SAMPLES USING MULTI-DIMENSIONAL FLUID SENSORS - The present invention provides multi-dimensional sensors with fluidic flow channels for processing fluid samples. | 09-04-2014 |
Charles R. Liu, Charlotte, NC US
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20140108237 | Automatic Savings Program - A computer implemented method of processing a financial transaction executed by first person includes determining an automatic savings amount from the financial transaction by rounding up the amount of the financial transaction to the nearest dollar. The method further includes debiting the calculated savings amount from an account of the first person and crediting the savings amount to an account of a second person. | 04-17-2014 |
Chunlei Liu, Chapel Hill, NC US
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20110262021 | SYSTEMS AND METHODS FOR SUSCEPTIBILITY TENSOR IMAGING - The present disclosure provides a method and system for quantifying and making images of tissue anisotropy property based on magnetic resonance imaging (MRI). The systems and methods provided herein utilize orientation distribution of magnetic susceptibility to characterize magnetic susceptibility anisotropy (MSA) inside biological tissues. This MSA may be intrinsic property of the tissue or may be induced by the presence of external agents. In certain embodiments, the MSA is displayed as an orientation distribution function of susceptibility and/or may be described by mathematical quantities such as tensors (e.g., symmetric or asymmetric second order or higher order tensors) and spherical harmonics. In other embodiments, the MSA is characterized using a second order tensor named apparent susceptibility tensor (AST). | 10-27-2011 |
20120321162 | SYSTEMS AND METHODS FOR IMAGING AND QUANTIFYING TISSUE MAGNETISM WITH MAGNETIC RESONANCE IMAGING - Systems and methods for imaging and quantifying tissue magnetism with magnetic resonance imaging (MRI) are disclosed. According to an aspect, a method for MRI includes using an MRI system to acquire multiple image echoes of an object. The method also includes combining the image echoes. Further, the method includes generating an image of the object based on the combined image echoes for depicting a characteristic of the object. | 12-20-2012 |
20130241550 | SYSTEMS AND METHODS FOR SUSCEPTIBILITY TENSOR IMAGING - The present disclosure provides a method and system for quantifying and making images of tissue anisotropy property based on magnetic resonance imaging (MRI). The systems and methods provided herein utilize orientation distribution of magnetic susceptibility to characterize magnetic susceptibility anisotropy (MSA) inside biological tissues. This MSA may be intrinsic property of the tissue or may be induced by the presence of external agents. In certain embodiments, the MSA is displayed as an orientation distribution function of susceptibility and/or may be described by mathematical quantities such as tensors (e.g., symmetric or asymmetric second order or higher order tensors) and spherical harmonics. In other embodiments, the MSA is characterized using a second order tensor named apparent susceptibility tensor (AST). | 09-19-2013 |
20140103929 | SYSTEMS AND METHODS FOR SUSCEPTIBILITY TENSOR IMAGING IN THE P-SPACE - Systems and methods for susceptibility tensor imaging in the p-space are disclosed. An example method includes using an MRI system to generate an MRI signal of an object. The method may also include conducting a multipole analysis of the MRI signal in a subvoxel Fourier spectral space (p-space). Further, the method may include sampling the p-space with pulsed field gradients to determine a set of dipole and quadrupole susceptibility tensors. The method may also include generating an image of the object based on the set of dipole and quadrupole susceptibility tensors for depicting a characteristic of the object. | 04-17-2014 |
Danwei Liu, Cary, NC US
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20140265922 | LIGHTING APPARATUS AND METHODS USING RECONFIGURABLE DIMMING MAPPING - A lighting apparatus includes at least one light emitting device and a reconfigurable driver circuit configured to drive the at least one light emitting device with an intensity that varies responsive to a dimming signal according to an adjustable mapping of the dimming signal to output of the light emitting device. In some embodiments, the mapping may be configurable using circuit component selection. In further embodiments, the mapping may be provided by a data input. | 09-18-2014 |
Demin Liu, Carrboro, NC US
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20140234210 | METAL BISPHOSPHONATE NANOPARTICLES FOR ANTI-CANCER THERAPY AND IMAGING AND FOR TREATING BONE DISORDERS - Metal-bisphosphonate nanoparticles are disclosed. Also disclosed are pharmaceutical compositions including the metal-bisphosphonate nanoparticles, methods of preparing the metal-bisphosphonate nanoparticles and materials comprising the nanoparticles, and methods of using the compositions to treat cancer or bone-related disorders (e.g., bone-resorption-related diseases, osteoporosis, Paget's disease, and bone metastases) and as imaging agents. | 08-21-2014 |
Dingxiang Liu, Charlotte, NC US
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20150227787 | PHOTOGRAPH BILLPAY TAGGING - Tools for photograph billpay tagging of a digital image are provided. The digital image may correspond to a portion of text positioned upon a medium. The text may correspond to billpay information. The tool may define a graphical reference frame for the digital image. The tool may identify a set of glyphs within the text. The tool may translate a portion of the digital image into an estimated group of characters. The translated portion of the digital image may correspond to at least a part of the set of glyphs. The tool may tag the portion of the digital image with a tag. The tag may be coupled with a billpay input field. The billpay input field may be populated. The billpay input field may be populated with the group of estimated characters. The bill input field may be populated based on the coupling. | 08-13-2015 |
Guowen Liu, Cary, NC US
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20110198436 | Vehicle capable of driving on land, air or water - A vehicle capable of driving on land, air or water comprises of a fuselage ( | 08-18-2011 |
Haiyan Liu, Raleigh, NC US
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20110268911 | CONFORMAL COATING OF POLYMER FIBERS ON NONWOVEN SUBSTRATES - The present invention describes a novel process for the conformal coating of polymer fibers on nonwoven substrates. This process is based on the modification of polymer fiber surfaces by controlling the degree of etching and oxidation, which improves adhesion of initiators to the surface and facilitates subsequent conformal polymer grafting. The modified fiber surfaces render new functionalities to the surface, such as increasing hydrophilicity, attaching ligands or changing surface energy. The invention includes the modified polymer fibers produced by the process described herein. | 11-03-2011 |
20150284889 | CONFORMAL COATING OF POLYMER FIBERS ON NONWOVEN SUBSTRATES - The present invention describes a novel process for the conformal coating of polymer fibers on nonwoven substrates. This process is based on the modification of polymer fiber surfaces by controlling the degree of etching and oxidation, which improves adhesion of initiators to the surface and facilitates subsequent conformal polymer grafting. The modified fiber surfaces render new functionalities to the surface, such as increasing hydrophilicity, attaching ligands or changing surface energy. The invention includes the modified polymer fibers produced by the process described herein. | 10-08-2015 |
Huadong Liu, Research Triangle Park, NC US
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20120166886 | NON-DISRUPTIVE FAILOVER OF RDMA CONNECTION - A novel RDMA connection failover technique that minimizes disruption to upper subsystem modules (executed on a computer node), which create requests for data transfer. A new failover virtual layer performs failover of an RDMA connection in error so that the upper subsystem that created a request does not have knowledge of an error (which is recoverable in software and hardware), or of a failure on the RDMA connection due to the error. Since the upper subsystem does not have knowledge of a failure on the RDMA connection or of a performed failover of the RDMA connection, the upper subsystem continues providing requests to the failover virtual layer without interruption, thereby minimizing downtime of the data transfer activity. | 06-28-2012 |
20140136880 | NON-DISRUPTIVE FAILOVER OF RDMA CONNECTION - A novel RDMA connection failover technique that minimizes disruption to upper subsystem modules (executed on a computer node), which create requests for data transfer. A new failover virtual layer performs failover of an RDMA connection in error so that the upper subsystem that created a request does not have knowledge of an error (which is recoverable in software and hardware), or of a failure on the RDMA connection due to the error. Since the upper subsystem does not have knowledge of a failure on the RDMA connection or of a performed failover of the RDMA connection, the upper subsystem continues providing requests to the failover virtual layer without interruption, thereby minimizing downtime of the data transfer activity. | 05-15-2014 |
Jianguo Liu, Durham, NC US
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20090157320 | CHARACTERIZING AN EARTH SUBTERRANEAN STRUCTURE BY ITERATIVELY PERFORMING INVERSION BASED ON A FUNCTION - To characterize an earth subterranean structure using a measurement assembly including electromagnetic (EM) receivers and one or more EM sources, measured voltage data collected by EM receivers in response to transmission by one or more EM sources is received. Based on a model, predicted EM data is computed. Inversion is iteratively performed according to a function that computes a difference between the measured voltage data and a product of a term containing the predicted EM data and a term containing distortion data that accounts at least for distortion effect by an environment of the measurement assembly. The inversion is iteratively performed to solve for parameters of the model and the distortion data. | 06-18-2009 |
Jim Liu, Raleigh, NC US
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20110059492 | POLYPEPTIDES HAVING ALPHA-AMYLASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME - The present invention relates to isolated polypeptides having alpha-amylase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. | 03-10-2011 |
Juhua Liu, Cary, NC US
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20140265599 | Power Flow Analysis Method and Apparatus for Hybrid AC-DC Systems - Power flow in a hybrid AC-DC power system is analyzed by determining DC power injection variables as a function of AC state information for common coupling buses which connect AC and DC grids. The AC state information includes voltage magnitude and phase angle information for the common coupling buses and buses in the AC grid(s). The DC power injection variables indicate AC power injection into the one or more AC grids at the common coupling buses from the DC grid(s). The AC state information is revised iteratively as a function of the DC power injection variables and the sensitivity of the DC power injection variables to the AC state information, and the DC power injection variables and the sensitivity of the DC power injection variables are revised iteratively as a function of the revised AC state information until the power mismatch is acceptable. | 09-18-2014 |
20150092311 | METHODS, SYSTEMS, AND COMPUTER READABLE MEDIA FOR PROTECTION OF DIRECT CURRENT BUILDING ELECTRICAL SYSTEMS - Methods, systems, and computer readable media for providing protection of DC building electrical systems are disclosed. According to one aspect, a system for over-current protection of direct current (DC) building electrical systems includes a DC bus for providing DC power to a building and multiple DC feeder conductors for providing DC power to multiple locations within the building. Each DC feeder conductor is connected to the DC bus via a DC protection module having a fuse, a normally closed switch connected in parallel with the fuse, and a circuit breaker connected in series with the fuse and switch, where the switch is controllable to be closed to protect the fuse against transient current conditions and controllable to be open after the transient current conditions have subsided to allow the fuse to operate normally. | 04-02-2015 |
Lianghong Liu, Raleigh, NC US
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20090081857 | Non-polar and semi-polar GaN substrates, devices, and methods for making them - Non-polar or semi-polar (Al, Ga, In)N substrates are fabricated by re-growth of (Al, Ga, In)N crystal on (Al, Ga, In)N seed crystals, wherein the size of the seed crystal expands or is increased in the lateral and vertical directions, resulting in larger sizes of non-polar and semi-polar substrates useful for optoelectronic and microelectronic devices. One or more non-polar or semi-polar substrates may be sliced from the re-grown crystal. The lateral growth rate may be greater than the vertical growth rate. The seed crystal may be a non-polar seed crystal. The seed crystal may have crystalline edges of equivalent crystallographic orientation | 03-26-2009 |
20120211917 | Wafer Furnace with Variable Flow Gas Jets - A method of forming a sheet wafer 1) passes at least two filaments through a molten material to produce a partially formed sheet wafer, 2) directs a cooling fluid at a flow rate toward the partially formed sheet wafer to convectively cool a given portion of the partially formed sheet wafer, and 3) monitors the thickness of the given portion of the partially formed sheet wafer. To ensure appropriate thicknesses of the wafer, the method controls the flow rate of the cooling fluid as a function of the thickness of the given portion of the partially formed sheet wafer. | 08-23-2012 |
20150279675 | GROUP III NITRIDE ARTICLES AND METHODS FOR MAKING SAME - Group III (Al, Ga, In)N single crystals, articles and films useful for producing optoelectronic devices (such as light emitting diodes (LEDs), laser diodes (LDs) and photodetectors) and electronic devices (such as high electron mobility transistors (HEMTs)) composed of III-V nitride compounds, and methods for fabricating such crystals, articles and films. | 10-01-2015 |
Lianghong Liu, Cary, NC US
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20100044718 | Group III Nitride Articles and Methods for Making Same - Group III (Al, Ga, In)N single crystals, articles and films useful for producing optoelectronic devices (such as light emitting diodes (LEDs), laser diodes (LDs) and photodetectors) and electronic devices (such as high electron mobility transistors (HEMTs)) composed of III-V nitride compounds, and methods for fabricating such crystals, articles and films. | 02-25-2010 |
20100327291 | Single crystal group III nitride articles and method of producing same by HVPE method incorporating a polycrystalline layer for yield enhancement - In a method for making a GaN article, an epitaxial nitride layer is deposited on a single-crystal substrate. A 3D nucleation GaN layer is grown on the epitaxial nitride layer by HVPE under a substantially 3D growth mode. A GaN transitional layer is grown on the 3D nucleation layer by HVPE under a condition that changes the growth mode from the substantially 3D growth mode to a substantially 2D growth mode. A bulk GaN layer is grown on the transitional layer by HVPE under the substantially 2D growth mode. A polycrystalline GaN layer is grown on the bulk GaN layer to form a GaN/substrate bi-layer. The GaN/substrate bi-layer may be cooled from the growth temperature to an ambient temperature, wherein GaN material cracks laterally and separates from the substrate, forming a free-standing article. | 12-30-2010 |
20110198590 | SINGLE CRYSTAL GROUP III NITRIDE ARTICLES AND METHOD OF PRODUCING SAME BY HVPE METHOD INCORPORATING A POLYCRYSTALLINE LAYER FOR YIELD ENHANCEMENT - In a method for making a GaN article, an epitaxial nitride layer is deposited on a single-crystal substrate. A 3D nucleation GaN layer is grown on the epitaxial nitride layer by HVPE under a substantially 3D growth mode. A GaN transitional layer is grown on the 3D nucleation layer by HVPE under a condition that changes the growth mode from the substantially 3D growth mode to a substantially 2D growth mode. A bulk GaN layer is grown on the transitional layer by HVPE under the substantially 2D growth mode. A polycrystalline GaN layer is grown on the bulk GaN layer to form a GaN/substrate bi-layer. The GaN/substrate bi-layer may be cooled from the growth temperature to an ambient temperature, wherein GaN material cracks laterally and separates from the substrate, forming a free-standing article. | 08-18-2011 |
20130264569 | SINGLE CRYSTAL GROUP III NITRIDE ARTICLES AND METHOD OF PRODUCING SAME BY HVPE METHOD INCORPORATING A POLYCRYSTALLINE LAYER FOR YIELD ENHANCEMENT - In a method for making a GaN article, an epitaxial nitride layer is deposited on a single-crystal substrate. A 3D nucleation GaN layer is grown on the epitaxial nitride layer by HVPE under a substantially 3D growth mode. A GaN transitional layer is grown on the 3D nucleation layer by HVPE under a condition that changes the growth mode from the substantially 3D growth mode to a substantially 2D growth mode. A bulk GaN layer is grown on the transitional layer by HVPE under the substantially 2D growth mode. A polycrystalline GaN layer is grown on the bulk GaN layer to form a GaN/substrate bi-layer. The GaN/substrate bi-layer may be cooled from the growth temperature to an ambient temperature, wherein GaN material cracks laterally and separates from the substrate, forming a free-standing article. | 10-10-2013 |
20150200256 | GROUP III NITRIDE ARTICLES HAVING NUCLEATION LAYERS, TRANSITIONAL LAYERS, AND BULK LAYERS - Group III (Al, Ga, In)N single crystals, articles and films useful for producing optoelectronic devices (such as light emitting diodes (LEDs), laser diodes (LDs) and photodetectors) and electronic devices (such as high electron mobility transistors (HEMTs)) composed of III-V nitride compounds, and methods for fabricating such crystals, articles and films. | 07-16-2015 |
Lianghong Liu, Carey, NC US
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20140162441 | SINGLE CRYSTAL GROUP III NITRIDE ARTICLES AND METHOD OF PRODUCING SAME BY HVPE METHOD INCORPORATING A POLYCRYSTALLINE LAYER FOR YIELD ENHANCEMENT - In a method for making a GaN article, an epitaxial nitride layer is deposited on a single-crystal substrate. A 3D nucleation GaN layer is grown on the epitaxial nitride layer by HVPE under a substantially 3D growth mode. A GaN transitional layer is grown on the 3D nucleation layer by HVPE under a condition that changes the growth mode from the substantially 3D growth mode to a substantially 2D growth mode. A bulk GaN layer is grown on the transitional layer by HVPE under the substantially 2D growth mode. A polycrystalline GaN layer is grown on the bulk GaN layer to form a GaN/substrate bi-layer. The GaN/substrate bi-layer may be cooled from the growth temperature to an ambient temperature, wherein GaN material cracks laterally and separates from the substrate, forming a free-standing article. | 06-12-2014 |
Mark Liu, Chapel Hill, NC US
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20100212807 | INSULATING ANGULAR DUCT SECTIONS FORMED ON AN AUTOMATIC COIL LINE - An angular insulated duct section and method for insulating and forming same is provided. A multi-layer composite sheet is provided, including a first duct layer of sheet metal having two opposed surfaces. On one of the sheet metal surfaces is attached a viscoelastic foam sheet layer. The foam sheet layer includes at least one of (A) a viscoelastic open-cell foam layer, or (B) a viscoelastic formally closed-cell foam layer in which at least a portion of closed cells therein has been opened. A substantially linear corner bend is formed in the composite sheet so as to form the angular insulated duct section with the sheet metal layer on an outside thereof and the foam sheet layer on an inside thereof. The corner bend is formed without substantial at least one of distortion or deformation of the multi-layer composite sheet adjacent the bend. | 08-26-2010 |
Qiuhua Liu, Durham, NC US
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20080288255 | System and method for quantifying, representing, and identifying similarities in data streams - A method of quantifying similarities between sequential data streams typically includes providing a pair of sequential data streams, designing a Hidden Markov Model (HMM) of at least a portion of each stream; and computing a quantitative measure of similarity between the streams using the HMMs. For a plurality of sequential data streams, a matrix of quantitative measures of similarity may be created. A spectral analysis may be performed on the matrix of quantitative measure of similarity matrix to define a multi-dimensional diffusion space, and the plurality of sequential data streams may be graphically represented and/or sorted according to the similarities therebetween. In addition, semi-supervised and active learning algorithms may be utilized to learn a user's preferences for data streams and recommend additional data streams that are similar to those preferred by the user. Multi-task learning algorithms may also be applied. | 11-20-2008 |
Quan Liu, Durham, NC US
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20080270091 | SCALING METHOD FOR FAST MONTE CARLO SIMULATION OF DIFFUSE REFLECTANCE SPECTRA FROM MULTI-LAYERED TURBID MEDIA AND METHODS AND SYSTEMS FOR USING SAME TO DETERMINE OPTICAL PROPERTIES OF MULTI-LAYERED TURBID MEDIUM FROM MEASURED DIFFUSE REFLECTANCE - The presently disclosed subject matter relates to multilayered scaling methods that allow for implementation of fast Monte Carlo simulations of diffuse reflectance from multilayered turbid media. The disclosed methods employ photon trajectory information provided by only a single baseline simulation, from which the diffuse reflectance can be computed for a wide range of optical properties in a multilayered turbid medium. A convolution scheme is also incorporated to calculate diffuse reflectance for specific fiber-optic probe geometries. Also provided are systems for fast Monte Carlo simulation of diffuse reflectance of a multilayered turbid medium to rapidly determine diffuse reflectance for the multilayered turbid medium with known optical properties and for using the scaled diffuse reflectance to determine optical properties of a turbid medium having unknown optical properties. | 10-30-2008 |
Renshui Liu, Research Triangle Park, NC US
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20150337302 | BIOLOGICAL CONTROL OF COLEOPTERAN PESTS - Disclosed are double stranded RNA molecules that are toxic to coleopteran insects. In particular, dsRNA molecules that capable of interfering with pest IAP genes and that are toxic to the target pest are provided. Further, methods of making and using the interfering RNA, for example in transgenic plants to confer protection from insect damage are disclosed. | 11-26-2015 |
Rihe Liu, Chapel Hill, NC US
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20140086835 | Methods and Compositions for Heptameric Targeting Ligands - The present invention provides a self assembly molecule having an affinity for one or more target molecules, for use in formation of a heptameric complex, comprising: a) a monomer comprising a multimerization domain of Archaeal Sm1 (AF-Sm1) protein or SM-like ribonucleoprotein from other organisms, able to interact with other molecules of the same monomer comprising a multimerization domain of AF-Sm1 protein or SM-like ribonucleoprotein to self-assemble into a heptamer; and b) a target binding domain or peptide attached directly or via a linker to the monomer of (a). Also provided are heptamers comprising these self assembly molecules and methods for their use in therapy, imaging and diagnostics. | 03-27-2014 |
Robort Liu, Waxhaw, NC US
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20130333458 | OPTIMAL TIRE PERFORMANCE INDICATOR - A tire performance indicator for a tire includes at least one tread wear indicator region structured and arranged in a tread region of the tire and at least one performance symbol guide structured and arranged approximate a sidewall region of the tire. | 12-19-2013 |
Ruopeng Liu, Durham, NC US
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20100156573 | METAMATERIALS FOR SURFACES AND WAVEGUIDES - Complementary metamaterial elements provide an effective permittivity and/or permeability for surface structures and/or waveguide structures. The complementary metamaterial resonant elements may include Babinet complements of “split ring resonator” (SRR) and “electric LC” (ELC) metamaterial elements. In some approaches, the complementary metamaterial elements are embedded in the bounding surfaces of planar waveguides, e.g. to implement waveguide based gradient index lenses for beam steering/focusing devices, antenna array feed structures, etc. | 06-24-2010 |
20150116187 | METAMATERIALS FOR SURFACES AND WAVEGUIDES - Complementary metamaterial elements provide an effective permittivity and/or permeability for surface structures and/or waveguide structures. The complementary metamaterial resonant elements may include Babinet complements of “split ring resonator” (SRR) and “electric LC” (ELC) metamaterial elements. In some approaches, the complementary metamaterial elements are embedded in the bounding surfaces of planar waveguides, e.g. to implement waveguide based gradient index lenses for beam steering/focusing devices, antenna array feed structures, etc. | 04-30-2015 |
Shi V. Liu, Apex, NC US
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20120196311 | Using cells reprogrammed with oncogenic factors for screening anti-neoplastic agents - Cells reprogrammed with oncogenic factors (CROFs) include incorrectly programmed stem cells such as induced pluripotent stem cells (iPSCs). The present application discloses linkages between iPS reprogramming and its potential roles in neoplastic transformation and thus establishes a foundation for using iPSCs as a class of CROFs for screening anti-neoplastic agents. The screening process involves examining the capability of a single agent or a combination of multiple agents in suppressing a neoplastic process including aerobic glycolysis and the related anabolism and thus inhibiting excessive reproduction of the neoplastic cell. In addition, agents are also screened for their potential in inhibiting invasion and migration of neoplastic cells. Anti-neoplastic agents found through methods disclosed here may represent wide-spectrum anti-neoplastic agents but possess very limited side effect because they target at one or more unique aspects of neoplastic processes, rather than affecting one or more living processes common to all cells including normal cells. | 08-02-2012 |
20140134667 | Using Induced Pluripotent Stem Cells for Screening Anti-Neoplastic Agents - The invention uses induced pluripotent stem cells (iPSCs) for screening anti-neoplastic agents by examining the capability of a single agent, compound or drug, or a combination of multiple agents, compounds or drugs, for inhibiting or suppressing one or more neoplastic activities or processes, including aerobic glycolysis and neoplastic anabolism and, thus, inhibiting rapid growth and excessive reproduction of neoplastic cells. Agents, compounds or drugs may also be screened for their potential in inhibiting an invasion and/or migration of neoplastic cells into healthy or normal tissues and/or cells and a metastasis of neoplastic cells into other sites of the body. Anti-neoplastic agents, compounds and/or drugs found through these methods may represent broad-spectrum anti-neoplastic agents, compounds and/or drugs that preferentially target and damage neoplastic tumor or cancer cells but exert limited or minimal harm to normal or healthy cells. | 05-15-2014 |
Siwen Liu, Raleigh, NC US
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20130211267 | APPARATUS AND METHOD FOR BATTERY-FREE BLOOD PRESSURE MONITOR - A battery-free electronic blood pressure measuring apparatus comprising a cuff ( | 08-15-2013 |
Wanbing W. Liu, Cary, NC US
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20110198436 | Vehicle capable of driving on land, air or water - A vehicle capable of driving on land, air or water comprises of a fuselage ( | 08-18-2011 |
Weicheng Liu, Huntersville, NC US
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20090063361 | Risk and Reward Assessment Mechanism - A data driven and forward looking risk and reward appetite methodology for consumer and small business is described. The methodology includes customer segmentation to create pools of homogeneous assets in terms of revenue and loss characteristics, forward looking simulation to forecast expected values and volatilities of revenue and loss, and risk and reward optimization of the portfolio. One methodology used for modeling revenue and loss is a generalized additive effect decomposition model to fit historical data. Based on the model, a segmentation procedure is performed, which allows for creation of groups of customers with similar revenue and loss characteristics. An estimation procedure for the model is developed and a simulation strategy to forecast and simulate revenue and loss volatility is developed. Efficient frontier curves of risk (e.g., return volatility) and reward (e.g., expected return) are created for the current portfolio under various economic scenarios. | 03-05-2009 |
20090327036 | DECISION SUPPORT SYSTEMS USING MULTI-SCALE CUSTOMER AND TRANSACTION CLUSTERING AND VISUALIZATION - Systems, methods and consumer-readable media for using multi-scale customer and transaction clustering and visualization according to the invention have been provided. Systems and methods according to the invention may use program code to obtain customer transaction data and categorize obtained customer transaction data. The systems and methods may also analyze the categorized customer transaction data in order to identify patterns among the data. The systems and methods may also use the identified patterns to isolate a selected number of behavioral factors and group customers into population segments based on the behavioral factors. | 12-31-2009 |
Wenjin Liu, Chapel Hill, NC US
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20140378469 | LKB1/STK11 DELETION IN MELANOMA AND RELATED METHODS - LKB1 mutation status and/or expression, YES expression and phosphorylation level; and/or CD24 expression are employed to predict melanoma prognosis and response to therapeutics. Inhibitors (including targeted inhibitors) of SRC family kinases (especially YES) are employed to treat melanoma. | 12-25-2014 |
Wennuan Liu, Clemmons, NC US
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20110023178 | High threonine producing lines of nicotiana tobacum and methods for producing - The present invention provides a method for producing plants with a desired phenotypic trait which comprises subjecting plants to mutagenesis, screening chimeric progeny for plants having the desired phenotypic trait, and propagating the survivors. In an embodiment, the phenotypic trait comprises an altered amino acid content. Preferably, the technique is used to generate | 01-27-2011 |
Xiaji Astor Liu, Raleigh, NC US
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20140203931 | GESTURE-BASED COMMUNICATION SYSTEMS AND METHODS FOR COMMUNICATING WITH HEALTHCARE PERSONNEL - Gesture-based communication systems and methods for communicating with healthcare personnel are disclosed. According to an aspect, a system is disclosed that includes a movement detector configured to detect movement of muscle and to generate a wireless signal in response to detection of the muscle movement. The system also includes a base station in wireless communication with the movement detector, and configured to implement a predetermined action based on the wireless signal. The base station may be configured to interface with a healthcare call system such as in a hospital environment. The base station may control the healthcare call system to communicate a notification signal based on the wireless signal. | 07-24-2014 |
Xianhua Liu, Chapel Hill, NC US
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20140344668 | SYSTEMS AND METHODS FOR PROCESSING MODIFIABLE FILES GROUPED INTO THEMED DIRECTORIES FOR PRESENTATION OF WEB CONTENT - Systems and methods for processing modifiable files grouped into themed directories for presentation of web content are disclosed. According to an aspect, a method includes grouping a plurality of modifiable files into one or more directories for use by a World Wide Web application. Further, the method includes associating a unique theme with the one or more directories. The method also includes processing the files based on the theme for presenting web content. | 11-20-2014 |
Xiaofeng Liu, Cary, NC US
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20090313383 | DATACASTING SYSTEM WITH AUTOMATIC DELIVERY OF SERVICE MANGEMENT CAPABILITY - A datacast system, and associated apparatus and method for automatically managing a data object or objects within a hierarchical carousel structure by enabling, among other functions, the dynamic allocation of bandwidth to each carousel within the structure. The dynamic bandwidth allocation enables a server platform to redistribute the bandwidth allocated to a carousel or set of data objects to adjust to desired changes in object transmission policies or priorities of a datacast application. | 12-17-2009 |
20100287298 | DATACASTING SYSTEM WITH HIERARCHICAL DELIVERY QUALITY OF SERVICE MANAGEMENT CAPABILITY - Datacasting systems may include one or more compound carousels each managing one or more elementary carousels, and managed by a bandwidth manager. Subsets of compounds carousels may be identified, for example, according to priority levels. Bandwidth allocations may be determined for the compound carousels. For example, the bandwidth manager may utilize multiple bandwidth allocation cycles to determine the bandwidth allocations. The multiple bandwidth allocation cycles may form a sequence. Each bandwidth allocation cycle may at least partially allocate an available datacasting bandwidth resource to at least one of the identified subsets of the compound carousels. The allocations may be based at least in part on desired bandwidths determined by the compound carousels and/or one or more bandwidth guidelines of datacast sessions associated with the compound carousels. | 11-11-2010 |
20120226816 | DATACASTING SYSTEM WITH HIERARCHICAL DELIVERY QUALITY OF SERVICE MANAGEMENT CAPABILITY - Datacasting systems may include one or more compound carousels each managing one or more elementary carousels, and managed by a bandwidth manager. Subsets of compounds carousels may be identified, for example, according to priority levels. Bandwidth allocations may be determined for the compound carousels. For example, the bandwidth manager may utilize multiple bandwidth allocation cycles to determine the bandwidth allocations. The multiple bandwidth allocation cycles may form a sequence. Each bandwidth allocation cycle may at least partially allocate an available datacasting bandwidth resource to at least one of the identified subsets of the compound carousels. The allocations may be based at least in part on desired bandwidths determined by the compound carousels and/or one or more bandwidth guidelines of datacast sessions associated with the compound carousels. | 09-06-2012 |
20130188488 | USING ROUTING INFORMATION AND INTER-LAYER RELATIONSHIPS TO DETERMINE UTILIZATION IN A TRANSPORT NETWORK - Embodiments provide systems, methods, and computer program products for mapping higher-layer circuits, links, flows, and services to lower layer circuit and connection elements to determine utilization of the lower layer circuit elements based on the high-layer traffic. Higher layer configuration data and lower layer configuration data are imported to populate a model. An inter-layer relationship is either directly or indirectly mapped from the higher layers to the lower layer. Once the inter-layer relationship is established, the higher-layer circuits, links, flows, and services are inspected using the lower layer circuit and connection elements. Circuit and packet-based utilization is determined for the lower layer elements based on the higher-layer traffic flows. | 07-25-2013 |
Xiaotao Liu, Raleigh, NC US
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20120083416 | METHOD FOR MAKING A COMPOSITE HIGH-TEMPERATURE SUPERCONDUCTOR - A method for making a composite superconductor and a superconductor made using the method. Superconducting filaments are embedded in a matrix material. Oxygen-containing elements are also embedded in the matrix material, with the oxygen-containing elements preferably being dispersed evenly among the superconducting filaments. A surrounding reinforcement material contains the other elements and preferably seals the superconductor from the surrounding atmosphere. | 04-05-2012 |
20150270471 | FORMATION OF BISMUTH STRONTIUM CALCIUM COPPER OXIDE SUPERCONDUCTORS - A BÏ2212 article may be formed by mixing metallic precursor powders including bismuth, strontium, calcium and copper in an oxygen-free atmosphere, mechanically alloying the metallic precursor powders in an oxygen-free atmosphere, and heating the metallic precursor alloy according to a temperature profile. The profile may include a ramp-up stage during which the alloy is heated to a peak temperature in an oxygen-free atmosphere, a dwell stage during which the alloy is held at the peak temperature for a dwell time, and a ramp-down stage during which the alloy is cooled from the peak temperature. During at least a portion of the dwell stage, the oxygen-free atmosphere is switched to an oxygen-inclusive atmosphere, wherein the alloy is oxidized to form a superconducting oxide, which may be sintered during or after oxidation. The alloy may be formed into a shape, such as a wire, prior to oxidizing. | 09-24-2015 |
Xue Liu, Advanced, NC US
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20150309261 | GRATING-COUPLER ASSEMBLY WITH SMALL MODE-FIELD DIAMETER FOR PHOTONIC-INTEGRATED-CIRCUIT SYSTEMS - A grating-coupler assembly with a small mode-field diameter for photonic-integrated-circuit systems is disclosed. The assembly includes a silicon waveguide supported by a silicon-on-insulator substrate, and a grating coupler supported by the substrate and optically coupled to the silicon waveguide. The assembly has an optical fiber with a mode-field diameter in the range from 5 μm to 6 μm. One end of the optical fiber is disposed adjacent the grating coupler to define a coupling efficiency of 0.7 or greater. | 10-29-2015 |
Yaping Liu, Durham, NC US
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20110021475 | Compositions And Methods for Treatment Of Fibrosis - Methods for the treatment of fibrosis, including liver fibrosis, via administration of FXR agonists are provided. | 01-27-2011 |
Yongning Liu, Apex, NC US
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20110207950 | VINYL-CONTAINING COMPOUNDS AND PROCESSES FOR MAKING THE SAME - The present invention provides a process for forming vinyl-containing compounds including the steps of: a) reacting in a nitrogen atmosphere a dicarboxylic acid and/or anhydride and a functional mono or polyfunctional alcohol to provide a hydroxyl-containing polyester; b) reacting the hydroxyl-containing polyester with a vinyl-containing organic acid in the presence of an esterification catalyst, a polymerization inhibitor and an azeotropic agent; and c) reacting the vinyl functional esterified intermediate, residual esterification catalyst and residual vinyl-containing organic acid with an epoxy to provide the vinyl-containing compound. | 08-25-2011 |
20140171568 | VINYL-CONTAINING COMPOUNDS WITH HIGH HEAT DISTORTION - A process for forming a thermosetting resin in a nitrogen atmosphere is provided. The process includes the steps of a) reacting a polycarboxylic acid and/or anhydride and a polyhydric alcohol to provide a hydroxyl-containing intermediate; b) reacting the hydroxyl-containing intermediate with a vinyl-containing organic acid or vinyl containing alkyl ester in the presence of an esterification catalyst, a polymerization inhibitor and an azeotropic agent; and c) reacting any residual vinyl-containing organic acid and residual esterification catalyst with an epoxide. | 06-19-2014 |
Yuehua Liu, Chapel Hill, NC US
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20150294031 | Predicting the Carbon Footprint of Urban Stormwater Infrastructure - A planning system for planning the landscaping of a particular piece of land in terms of carbon footprint models predefined types of stormwater management infrastructure and assists a user in constructing a plan for managing the land's stormwater according to carbon footprint. The net carbon footprint of the plan is calculated according to type-specific equations that formulate carbon embodied in the materials, emitted during the construction, emitted during the maintenance, and sequestered by the materials of the one or more types of stormwater management infrastructure employed by the plan. The user is then presented with information useful for determining the net carbon footprint or determining a plan that most closely achieves a target net carbon footprint. | 10-15-2015 |
Zhi Liu, Jamestown, NC US
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20100087520 | STABLE SOLUTIONS OF ORLISTAT FOR PHARMACEUTICAL DOSAGE FORMS - Liquid orlistat-containing fill materials suitable for encapsulating in hard or soft capsules are described herein. The fill material contains orlistat dissolved in one or more medium chain triglycerides or medium chain partial triglycerides, one or more citrate esters, and combinations thereof. The fill material can also contain one or more pharmaceutically acceptable excipients. In one embodiment, the fill material is substantially free of surfactants. The fill material can be encapsulated in hard or soft, gelatin or non-gelatin capsules. The capsules may be coated to modify release of orlistat from the capsule. Alternatively, the fill material can be encapsulated in an enteric capsule, wherein the enteric polymer is a component of the capsule shell, rather than a coating over the capsule shell. The fill materials are stable at elevated temperatures over an extended period of time and allow for high loadings of orlistat (e.g., 20% w/w or higher). | 04-08-2010 |
20100255085 | Progesterone Solutions for Increased Bioavailability - Fill materials for hydrophobic drugs, such as progesterone, and methods of making and using thereof are described herein. The fill material contains the hydrophobic drug dissolved in one or more fatty acids. The concentration of the hydrophobic drug is typically from about 7% to about 50% by weight of the fill material. The concentration of the one or more fatty acids is from about 60% to about 95% by weight of the carrier. The formulation also contains an organic acid and one or both of one or more pharmaceutically acceptable alcohols and one or more pharmaceutically acceptable mono-, di-, or triesters of medium or long chain fatty acids. The fill material can be encapsulated in a hard or soft capsule. The formulations described herein have a higher dissolution rate and faster onset of dissolution compared to micronized progesterone suspended in an oil and thus should have increased bioavailability in vivo. | 10-07-2010 |