Patent application number | Description | Published |
20080207759 | METHOD FOR PROTECTING MITOCHONDRIA - The present invention relates to a method for protecting mitochondria from damage in a mammalian subject, which comprises administering an effective amount of a prostaglandin compound to a subject in need thereof. Also provided is a method for treating mitochondrial dysfunction as well as a condition associated with mitochondrial dysfunction in a mammalian subject, which comprises administering an effective amount of a prostaglandin compound to a subject in need thereof. | 08-28-2008 |
20080255227 | NOVEL COMPOSITION AND METHOD FOR STABILIZING THE SAME - Disclosed is a novel composition comprising a novel bi-cyclic compound, which is expected to be pharmaceutically active, and a glyceride. The stability of the bi-cyclic compound can be improved significantly by dissolving the same in a glyceride. | 10-16-2008 |
20090012165 | PHARMACEUTICAL COMBINATION OF NSAID AND PROSTAGLANDIN COMPOUND - Provided is a method for treating a condition or disease which is one of the indications for NSAID use, which comprises administering a combination of:
| 01-08-2009 |
20090022787 | PHARMACEUTICAL COMPOSITION COMPRISING 11-DEOXY- PROSTAGLANDIN COMPOUND AND METHOD FOR STABILIZING THE COMPOUND - Provided is a pharmaceutical composition comprising a 11-deoxy-prostaglandin compound represented by formula (I): | 01-22-2009 |
20090062381 | AQUEOUS COMPOSITION - In an aqueous composition comprising a 15-keto-prostaglandin compound as an active ingredient, a polyoxyethylene castor oil derivative is admixed. By admixing a polyoxyethylene castor oil derivative, the solubility of the 15-keto-PG compound in water is increased. In a preferable embodiment, the aqueous composition may further comprise a quaternary ammonium type cationic surface active agent as a preservative. The composition of this embodiment exhibits high antimicrobial preservative effectiveness against indigenous bacterium in the eyes such as | 03-05-2009 |
20090209643 | METHOD FOR MODULATING STEM CELL GROWTH - In one embodiment, provided is a composition comprising a prostaglandin compound for modulating stem cell proliferation and/or differentiation in a mammalian subject. In another embodiment, the instant application is a composition comprising a prostaglandin compound for, which comprises a prostaglandin compound for modulating proliferation and/or differentiation of stem cells of a mammalian subject, in which the stem cells are contacted directly or indirectly with the composition of the invention. | 08-20-2009 |
20090298928 | COMPOSITION AND METHOD FOR SCALP AND HAIR TREATMENT - Provided is a composition for scalp and hair treatment, comprising a menthol derivative and a prostaglandin compound having two hetero atoms at the 15 position. The composition of the present invention is effective not only for preventing dandruff and itchy scalp but also for preventing or treating hair loss, baldness, or hair thinness. | 12-03-2009 |
20100087540 | PHARMACEUTICAL COMPOSITION - Provided is a pharmaceutical composition comprising: a) a prostaglandin compound; (b) a sugar alcohol; (c) a polyol; and (d) a pharmaceutically acceptable carrier. The composition of the present invention can be stored stably even in a polyethylene container. In addition, the composition of the present invention can be stored stably for a long term even if it comprises only a small amount of a preserving agent. | 04-08-2010 |
20100305203 | METHOD FOR MODULATING CLAUDIN MEDIATED FUNCTIONS - Disclosed is a method for modulating a claudin-mediated function in a mammalian subject which comprises administering to a subject in need thereof an effective amount of a specific fatty acid derivative. The application also discloses a method for treating a dermatological disease and a method for modulating an expression of a claudin in a mammalian subject using the same fatty acid derivative as above. | 12-02-2010 |
20110034424 | METHOD FOR THE LONG TERM NSAID USE - Provided is a method for the long term treatment of a condition or disease which is one of the indications for NSAID use in a human patient, which comprises administering to the patient a pharmaceutically effective amount of a NSAID and at least 36 mcg per day of cobiprostone or its pharmaceutically acceptable salt, ester, ether or amide. By administering cobiprostone or its pharmaceutically acceptable salt, ester, ether or amide in combination with a NSAID, the patient can receive the NSAID for longer time period. | 02-10-2011 |
20110054016 | METHOD FOR MODULATING CLAUDIN MEDIATED FUNCTIONS - Disclosed is a method for modulating a claudin-mediated function in a mammalian subject which comprises administering to a subject in need thereof an effective amount of a specific fatty acid derivative. The application also discloses a method for treating a dermatological disease and a method for modulating an expression of a claudin in a mammalian subject using the same fatty acid derivative as above. | 03-03-2011 |
20110064748 | PHARMACEUTICAL COMBINATION AND METHOD FOR TREATING TUMOR - Disclosed is a method for treating tumor in a mammalian subject, which comprises administering a combination of (a) an anti-tumor agent and (b) a fatty acid derivative represented by the formula (I): | 03-17-2011 |
20110275711 | METHOD FOR TREATING MACULAR EDEMA - Provided is a method for treating macular edema in a mammalian subject, comprising administering an effective amount of a fatty acid derivative to the subject in need thereof. The method of the present invention can effectively treat macular edema in a non-invasive manner. In one embodiment of the present invention, the fatty acid derivative is isopropyl unoprostone. | 11-10-2011 |
20110275715 | METHOD FOR TREATING RETINAL DISEASE - The present application provides a method for treating a retinal disease in a patient in need thereof, which comprises administering at least three drops of an ophthalmic composition comprising a fatty acid derivative as an active ingredient in an eye of the patient per day. | 11-10-2011 |
20120087864 | METHOD FOR DIAGNOSING AND/OR EVALUATING RETINAL DISEASE - The present application provides a method for diagnosing and/or evaluating the presence or absence, severity or degree of the improvement of a retinal disease in a subject, which comprises determining and/or evaluating circulatory parameters, retinal function, retina morphology and/or visual relating quality of life (QOL). | 04-12-2012 |
20120232139 | COMPOSITION FOR OCULAR TOPICAL ADMINISTRATION TREATMENT OCULAR HYPERTENSION AND GLAUCOMA - The present invention provides a composition for ocular topical administration for treating ocular hypertension and glaucoma, comprising latanoprost as an active ingredient, and (a) a polyol and/or sugar alcohol, (b) a nonionic surface active agent, and (c) an edetic acid compound. The composition of the present invention comprises lower amount of preservatives such as benzalkonium chloride comparative to the conventional product and therefore, can reduce incidence of the adverse side effects caused by the preservatives. In addition, the composition of the present invention can be stored stably at room temperatures for a long term. | 09-13-2012 |
20120259008 | METHOD FOR TREATING ASTHENOPIA - The present invention relates to a method for treating asthenopia, accommodative dysfunction or ocular pain comprising an administration of a specific prostaglandin compound to a mammalian subject. The present invention also relates to a composition for treating asthenopia, accommodative dysfunction or ocular pain comprising a specific prostaglandin compound. | 10-11-2012 |
20120270945 | METHOD FOR MODULATING CYTOKINE ACTIVITY - The present invention relates to a method for modulating cytokine activity, immunomodulation or treating esophagitis comprising an administration of a fatty acid derivative to a mammalian subject. The present invention also relates to a composition for modulating cytokine activity, immunomodulation or treating esophagitis comprising a fatty acid derivative. | 10-25-2012 |
20120277299 | METHOD FOR MODULATING ION TRANSPORTER - The present invention relates to a method for modulating ion transporter or treating disturbances of electrolyte transport during disease state, comprising an administration at a fatty acid derivative to a mammalian subject. The present invention also relates to a composition for modulating ion transporter or treating disturbances of electrolyte transport during disease state, comprising a fatty acid derivative. | 11-01-2012 |