Patent application number | Description | Published |
20110066111 | Stable co-formulation of hyaluronidase and immunoglobulin, and methods of use thereof - Provided herein are stable co-formulations of immunoglobulin and hyaluronidase that are stable to storage in liquid form at room temperature for at least 6 months and at standard refrigerator temperatures for 1-2 years. Such co-formulations can be used in methods of treating IG-treatable diseases or conditions by subcutaneous administration. | 03-17-2011 |
20110293598 | METHOD TO PRODUCE AN IMMUNOGLOBULIN PREPARATION WITH IMPROVED YIELD - The present invention provides improved methods for the manufacturing of IVIG products. These methods offer various advantages such as reduced loss of IgG during purification and improved quality of final products. In other aspects, the present invention provides aqueous and pharmaceutical compositions suitable for intravenous, subcutaneous, and/or intramuscular administration. In yet other embodiments, the present invention provides methods of treating a disease or condition comprising administration of an IgG composition provided herein. | 12-01-2011 |
20110293638 | METHOD TO PRODUCE AN IMMUNOGLOBULIN PREPARATION WITH IMPROVED YIELD - The present invention provides improved methods for the manufacturing of IVIG products. These methods offer various advantages such as reduced loss of IgG during purification and improved quality of final products. In other aspects, the present invention provides aqueous and pharmaceutical compositions suitable for intravenous, subcutaneous, and/or intramuscular administration. In yet other embodiments, the present invention provides methods of treating a disease or condition comprising administration of an IgG composition provided herein. | 12-01-2011 |
20130101579 | METHOD TO PRODUCE AN IMMUNOGLOBULIN PREPARATION WITH IMPROVED YIELD - The present invention provides improved methods for the manufacturing of IVIG products. These methods offer various advantages such as reduced loss of IgG during purification and improved quality of final products. In other aspects, the present invention provides aqueous and pharmaceutical compositions suitable for intravenous, subcutaneous, and/or intramuscular administration. In yet other embodiments, the present invention provides methods of treating a disease or condition comprising administration of an IgG composition provided herein. | 04-25-2013 |
20130224184 | METHOD TO PRODUCE AN IMMUNOGLOBULIN PREPARATION WITH IMPROVED YIELD - The present invention provides improved methods for the manufacturing of IVIG products. These methods offer various advantages such as reduced loss of IgG during purification and improved quality of final products. In other aspects, the present invention provides aqueous and pharmaceutical compositions suitable for intravenous, subcutaneous, and/or intramuscular administration. In yet other embodiments, the present invention provides methods of treating a disease or condition comprising administration of an IgG composition provided herein. | 08-29-2013 |
20150133644 | METHOD TO PRODUCE AN IMMUNOGLOBULIN PREPARATION WITH IMPROVED YIELD - The present invention provides improved methods for the manufacturing of IVIG products. These methods offer various advantages such as reduced loss of IgG during purification and improved quality of final products. In other aspects, the present invention provides aqueous and pharmaceutical compositions suitable for intravenous, subcutaneous, and/or intramuscular administration. In yet other embodiments, the present invention provides methods of treating a disease or condition comprising administration of an IgG composition provided herein. | 05-14-2015 |
Patent application number | Description | Published |
20150128900 | PILE HAMMER - A pile hammer includes a cylinder, a piston displaceably guided in the cylinder, and a striker displaceably guided in the cylinder. The striker is disposed underneath the piston in the operating position of the pile hammer. A combustion chamber is delimited axially by a face surface of the striker that lies in the interior of the cylinder and by a face surface of the piston. Using at least one fuel feed device a predetermined amount of fuel can be introduced into the combustion chamber during each working cycle. A primary fuel feed device is provided, which includes a primary fuel nozzle connected with a primary fuel tank having a fuel with great anti-knock properties. The primary fuel nozzle is structured as a high-pressure injection nozzle. An ignition oil feed device is also provided, which includes an ignition oil nozzle connected with an ignition oil tank having an ignition oil. The ignition oil nozzle is structured as a low-pressure injection nozzle. A method operates such a pile hammer. | 05-14-2015 |
20150129270 | DIESEL HAMMER PILE DRIVER - A diesel hammer pile driver has a cylinder, a piston displaceably guided in the cylinder and a striker displaceably guided in the cylinder. The striker is disposed underneath the piston in the operating position of the diesel hammer pile driver. A combustion chamber is delimited axially by a face surface of the striker that lies in the interior of the cylinder and by a face surface of the piston, and opens into a fuel feed device connected with a fuel tank disposed on the outside of the cylinder. Using the fuel feed device a predetermined amount of fuel can be introduced into the combustion chamber during each working cycle. The fuel tank is elastically mounted on the cylinder. | 05-14-2015 |
20150129271 | DIESEL HAMMER PILE DRIVER - A diesel hammer pile driver has a cylinder, a piston displaceably guided in the cylinder and a striker displaceably guided in the cylinder. The striker is disposed underneath the piston in the operating position of the diesel hammer pile driver. A combustion chamber is delimited axially by a face surface of the striker that lies in the interior of the cylinder and by a face surface of the piston, and opens into a fuel feed device. Using the fuel feed device a predetermined amount of fuel can be introduced into the combustion chamber during each working cycle. At least two working connectors are disposed to pass through the circumference wall of the cylinder at the level of the fuel feed device, wherein at least one working connector is provided with a muffler device. | 05-14-2015 |
20150275456 | PILE HAMMER - A pile hammer includes a cylinder, a piston displaceably guided in the cylinder, and a striker displaceably guided in the cylinder. The striker is disposed underneath the piston in the operating position of the pile hammer. A combustion chamber is delimited axially by a face surface of the striker that lies in the interior of the cylinder and by a face surface of the piston. Using at least one fuel feed device a predetermined amount of fuel can be introduced into the combustion chamber during each work cycle. At least one lubricant dispenser for conveying a lubricant between piston and cylinder is set up in such a manner that conveying of lubricant is brought about via the impact shock of the piston. | 10-01-2015 |
20150275457 | PILE HAMMER - A pile hammer includes a cylinder, a piston displaceably guided in the cylinder, and a striker displaceably guided in the cylinder. The striker is disposed underneath the piston in the operating position of the pile hammer. A combustion chamber is delimited axially by a face surface of the striker that lies in the interior of the cylinder and by a face surface of the piston. Using at least one fuel feed device a predetermined amount of fuel can be introduced into the combustion chamber during each work cycle. An end ring is disposed on the cylinder for forming a capture groove. The piston is provided with a step that projects outward, which makes contact with the capture groove in the upper end position of the piston, and the end ring is elastically connected with the cylinder. | 10-01-2015 |
20150275458 | PILE HAMMER - A pile hammer includes a cylinder, a piston displaceably guided in the cylinder, and a striker displaceably guided in the cylinder. The striker is disposed underneath the piston in the operating position of the pile hammer. A combustion chamber is delimited axially by a face surface of the striker that lies in the interior of the cylinder and by a face surface of the piston. Using at least one fuel feed device a predetermined amount of fuel can be introduced into the combustion chamber during each work cycle. The piston has a cavity that is filled, at least in part, with a movable filler. | 10-01-2015 |
Patent application number | Description | Published |
20120024375 | VACUUM ELEMENT AND METHOD FOR PRODUCING THE SAME - For the production of vacuum elements, which optionally contain fittings in the form of at least one solar module (photovoltaic element) and/or a solar collector or a display element, negative pressure is produced in a space between two flat components, in particular translucent or transparent plates, such as glass panes that are bound together via a bead made of sealing material, such that an arrangement that consists of a first component provided with a bead and at a distance therefrom but parallel to the second component arranged therein, is introduced into a vacuum chamber and pressed under vacuum. In this case, an elevated temperature also optionally can be applied to laminate films provided between the components with the components and optionally present fittings. | 02-02-2012 |
20120037293 | DEVICE AND METHOD FOR APPLYING SPACER TAPES TO GLASS PANES - An device for simultaneous application of elastoplastic spacer tapes to two glass panes with identical outline shape and identical dimensions has two application heads ( | 02-16-2012 |
20120085499 | DEVICE FOR APPLYING SPACER TAPE - A device for applying an elastoplastic spacer tape as a spacer during the production of insulating glass panes has at least two supply reels for spacer tapes, several driven tape guide rollers, and a movable application head for the selected spacer tape, with whose assistance the spacer tape is pressed onto a glass pane. For coating one or the other spacer tape, a coating station with two coating nozzles is provided, from which adhesive glue is sprayed on the lateral surfaces of the selected spacer tape. The spacer tape that is unneeded in each case is stopped in the application head in such a way that one or the other of the spacer tapes as desired, depending on which spacer tape is required for the production of a special insulating glass pane, is applied to the glass pane. Thus, the laborious threading and unthreading of spacer tapes is not necessary. | 04-12-2012 |
20120094040 | SPACER TAPE - A spacer tape ( | 04-19-2012 |
20120199272 | METHOD FOR PRODUCING INSULATING GLASS THAT IS FILLED WITH A GAS THAT IS DIFFERENT FROM AIR - To fill insulating glass with a gas other than air, between the spacer ( | 08-09-2012 |
20120230759 | JOINT BETWEEN THE ENDS OF PREFABRICATED SPACERS FOR INSULATING GLASS, AND PROCESS FOR PRODUCING SAID JOINT - A diffusion-tight joint ( | 09-13-2012 |
20120261056 | METHOD FOR ASSEMBLY OF INSULATION GLASS BLANKS - To implement assembly of insulation glass blanks ( | 10-18-2012 |
20120289132 | ARRANGEMENT FOR GUIDING TOOLS - An arrangement ( | 11-15-2012 |
20130040541 | DEVICE FOR CONVEYING PLATE-SHAPED ELEMENTS - Disclosed is a linear conveyor ( | 02-14-2013 |
20130099047 | METHOD AND APPARATUS FOR HANDLING SHEET BLANKS - To take blanks of sheets for producing laminated glass, from a cutting table, an adjustable takeoff roller onto which the sheet blanks are wound is used. To fix the beginning of the sheet blank to be taken off to the takeoff roller, openings for applying negative pressure are provided in the lateral surface of the takeoff roller. When a sheet blank is taken from the cutting table, the takeoff roller is brought into position at the beginning of the sheet blank to be taken off, the blank is fixed to the takeoff roller and the takeoff roller is then moved along the cutting table while rotating about its own axis, and so the sheet blank is wound up around the lateral surface of the takeoff roller. For laying down the sheet blank onto a glass pane during the production of laminated glass, a correspondingly reversed procedure may be used. | 04-25-2013 |
20130224386 | PROCESS AND MEANS FOR THE TREATMENT OF GLASS OBJECTS - Plate glass, in particular soda-lime plate glass, is treated with potassium water glass in order to alter the optical properties of soda-lime plate glass, in particular its reflection behaviour. The soda-lime plate glass is thermally treated after application of potassium water glass in order to achieve additional hardening of the soda-lime plate glass. The treated plate glass can be used, in particular, for cover plates of photovoltaic modules. | 08-29-2013 |
20130247901 | SOLAR COLLECTOR - A solar collector ( | 09-26-2013 |
20130312908 | METHOD FOR PRODUCING MODULES - In order to produce photovoltaic modules or modules bearing functional coatings, a strand ( | 11-28-2013 |
20140053605 | Method and Device for Tempering Glass - For a device for tempering flat glass, the glass panes ( | 02-27-2014 |
20140102622 | METHOD AND DEVICE FOR SEALING INSULATING GLASS BLANKS - A hot melt adhesive is introduced as a filling mass from the filling nozzle ( | 04-17-2014 |
20140131413 | METHOD AND DEVICE FOR PRODUCING EDGE CUTOUTS IN SHEET GLASS - To produce an edge cutout, in the shape of a segment of a circle in a glass pane, a cutting tool having a small cutting wheel is used to produce a circular arc-shaped score line, whose ends lie at the edge of the glass pane. By applying pressure to the region defined by the score line from the face having the score line and by counter-pressure from the opposite face, the part of the glass pane defined by the edge and the score line is separated from the glass pane. A device for carrying out the method, includes the small cutting wheel on a support and a head movable into an operative position to break out the portion in the shape of a segment of a circle, and a punch that can be extended from a support for the glass pane and engages on the face opposite the score line. | 05-15-2014 |
20140196402 | DEVICE FOR INSERTING DISTANCING CORDS - In order to insert at least two zick-zack-extending cords ( | 07-17-2014 |
20150034231 | SEALING AND DE-STACKING - When being sealed, insulating glass blanks ( | 02-05-2015 |
20150055434 | METHOD AND APPARATUS FOR CHANGING SPACERS - A device for mixing at least two fluid to pasty substances has a housing ( | 02-26-2015 |
20150074968 | METHOD AND APPARATUS FOR CHANGING SPACERS - A method and apparatus for the, preferably automated, changing of spacers in a plant having at least one applicator head for applying spacers to panel-shaped workpieces, in particular glass panes. Spacers from at least two sources are fed to the applicator head in an offset manner with respect to one another. A first spacer from a first source is separated. The resulting end of the first spacer and a start of the second spacer, which comes from a second source, are moved into a mutually assigned position by a changing device. Then, the end of the first spacer is connected to the start of the second spacer. A resulting connection of the first spacer with the second spacer runs through the plant until the connection has passed the applicator head. Thereafter, the second spacer is separated in a region between the connection and the applicator head. | 03-19-2015 |
20150075222 | METHOD AND ARRANGEMENT FOR CREATING BEVELS ON THE EDGES OF FLAT GLASS - When dividing glass using laser radiation into blanks ( | 03-19-2015 |
20150273807 | DEVICE FOR LAMINATING PLATE-SHAPED ARTICLES - A device for laminating plate-shaped articles, in particular glass panes, has two laminating rolls ( | 10-01-2015 |
20150375354 | METHOD AND DEVICE FOR TREATING THE SURFACE OF OBJECTS - When decoating a glass panel ( | 12-31-2015 |
20150375486 | METHOD AND TOOL FOR PROCESSING MATERIALS | 12-31-2015 |
20160060950 | Method and Device for Filling an Edge Joint of an Insulating Glass Element With a Sealing Compound - A stand of sealing compound is expelled from a nozzle into an edge joint of an insulating glass element to form around it a contiguous sealing compound bead. The sealing compound bead is formed discontinuously from several segments. At least one first segment is formed by the relative movement in a first circumferential direction of the insulating glass element, and at least one second segment is formed by the relative movement in a second, opposite circumferential direction. Each connection of segments of the sealing compound bead which is situated on a longitudinal side section of the circumference of the insulating glass element is formed such that the strand of the sealing compound is applied in the region of the end of a sealing compound bead already situated in the edge joint and is formed by the relative movement away from the end. | 03-03-2016 |
Patent application number | Description | Published |
20090093445 | RELEASE REAGENT FOR VITAMIN D COMPOUNDS - The present invention concerns a reagent composition for releasing vitamin D compounds bound to vitamin D-binding protein, a method for the detection of a 25-hydroxyvitamin D compound in which the 25-hydroxyvitamin D compound is released from vitamin D-binding protein using this reagent and the mixture obtained in this manner is analyzed, the use of the reagent to release vitamin D compounds as well as a kit for detecting 25-hydroxyvitamin D which contains the reagent for releasing vitamin D compounds in addition to the usual immunological reagents. | 04-09-2009 |
20100285603 | MEASUREMENT OF VITAMIN D - The present invention relates to a method of measuring a vitamin D metabolite in a sample, the method comprising the steps of (a) treating said sample with a vitamin D metabolite releasing reagent under conditions appropriate to release a vitamin D metabolite from vitamin D-binding protein and not to cause protein precipitation, (b) subjecting the treated sample obtained in step (a) to a chromatographic separation, and (c) measuring a vitamin D metabolite during or after said chromatographic separation. The present invention also relates to methods for determining the vitamin D status of a subject, for use in the diagnosis of disease, and to agents and kits for use in performing the methods of the invention. | 11-11-2010 |
20110160436 | METHOD TO SCREEN HIGH AFFINITY ANTIBODY - The current invention reports a method for producing an antibody comprising the steps of a) providing a plurality of hybridoma cells each expressing an antibody, b) determining the time dependent amount of said antibody bound to the respective antigen by surface plasmon resonance at different temperatures and different antibody concentrations, c) calculating with the time dependent amount determined in b) based on equations (II) to (XIII) at least the thermodynamic parameters (i) standard association binding entropy formula (A), (ii) standard dissociation binding entropy formula (B), (iii) standard binding entropy (ΔS°), (iv) free standard binding enthalpy (ΔG°), (v) standard dissociation free binding enthalpy formula (C), (vi) standard association free binding enthalpy formula (D), (vii) −TΔS°, (viii) dissociation rate constant k | 06-30-2011 |
20120156726 | VELOCITY FACTOR - The current invention is directed to the velocity factor. Based on the velocity factor antibodies can be classified, i.e. antibodies can be characterized on their binding properties as e.g. entropic or enthalpic antigen binder. A velocity factor based classification does not require detailed thermodynamic determinations and/or calculations. The velocity factor is the ratio of the antigen-antibody complex association rate constants ka determined at 37° C. and 13° C. As only two experimental determinations are required to calculate the velocity factor this is a fast and high-throughput suited method. | 06-21-2012 |
20140199782 | METHOD TO SCREEN HIGH AFFINITY ANTIBODY - The current invention reports a method for producing an antibody comprising the steps of a) providing a plurality of hybridoma cells each expressing an antibody, b) determining the time dependent amount of said antibody bound to the respective antigen by surface plasmon resonance at different temperatures and different antibody concentrations, c) calculating with the time dependent amount determined in b) based on equations (II) to (XIII) at least the thermodynamic parameters (i) standard association binding entropy (ΔS°‡ass), (ii) standard dissociation binding entropy (ΔS°‡diss), (iii) standard binding entropy (ΔS°), (iv) free standard binding enthalpy (ΔG°), (v) standard dissociation free binding enthalpy (ΔG°‡diss), (vi) standard association free binding enthalpy (ΔG°‡ass), (vii) −TΔS°, (viii) dissociation rate constant k | 07-17-2014 |
20140256915 | Velocity Factor - The current invention is directed to the velocity factor. Based on the velocity factor antibodies can be classified, i.e. antibodies can be characterized on their binding properties as e.g. entropic or enthalpic antigen binder. A velocity factor based classification does not require detailed thermodynamic determinations and/or calculations. The velocity factor is the ratio of the antigen-antibody complex association rate constants ka determined at 37° C. and 13° C. As only two experimental determinations are required to calculate the velocity factor this is a fast and high-throughput suited method. | 09-11-2014 |
20150104876 | RELEASE REAGENT FOR VITAMIN D COMPOUNDS - The present invention concerns a reagent composition for releasing vitamin D compounds bound to vitamin D-binding protein, a method for the detection of a 25-hydroxyvitamin D compound in which the 25-hydroxyvitamin D compound is released from vitamin D-binding protein using this reagent and the mixture obtained in this manner is analyzed, the use of the reagent to release vitamin D compounds as well as a kit for detecting 25-hydroxyvitamin D which contains the reagent for releasing vitamin D compounds in addition to the usual immunological reagents. | 04-16-2015 |