Simoni
David A. Simoni, Piedmont, SC US
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20080302441 | STORAGE COMPARTMENT - A storage compartment comprises an external enclosure having an opening and a holding compartment that is capable of being inserted into and withdrawn from the interior of the external enclosure through the opening in the external enclosure. Stored articles are contained within the holding compartment. The external enclosure and the holding compartment have coacting surfaces, and a seal is interposed between those coacting surfaces for sealing off the interior of the holding compartment to the entry of gases when the holding compartment is inserted into the external enclosure and the coacting surfaces of the external enclosure and the holding compartment are brought together in a sealing relationship with the seal. Complementary surfaces at the holding compartment and at the exterior of the external enclosure are in engagement with one another and provide surfaces along which the holding compartment travels when it is inserted into and withdrawn from the interior of the external enclosure. | 12-11-2008 |
Grace Simoni, Lubbock, TX US
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20110097746 | Orthogonal Method for the Removal of Transmissible Spongiform Encephalopathy Agents from Biological Fluids - A method comprising contacting a biological fluid comprising hemoglobin and at least one pathogenic agent with a first filter and generating a first filtrate; contacting the first filtrate with a nanofiltration device and generating a second filtrate; contacting the second filtrate with a chromatographic material and isolating an eluted fraction; contacting the eluted fraction with a hydrophobic solvent and generating a hydrophobic and a hydrophilic phase; and isolating the hydrophilic phase wherein the biological fluids comprise components of interest of equal to or less than about 65 kDa. A method comprising contacting a biological fluid comprising high molecular weight components and at least one pathogenic agent with a first filter and generating a first filtrate; contacting the first filtrate with a hydrophilic membrane and generating a second filtrate; contacting the second filtrate with a chromatographic material and isolating an eluted fraction; contacting the eluted fraction with a hydrophobic solvent and generating a hydrophobic and a hydrophilic phase; and isolating the hydrophilic phase, wherein the high molecular weight components have molecular weights greater than about 65 kDa. A method comprising subjecting a biological fluid comprising hemoglobin and at least one pathogenic agent to at least two filtration steps and thereby reducing the amount of pathogenic agent associated with the biological fluid. A method comprising removing transmissible spongiform encephalopathy agents in a hemoglobin solution of human and/or animal origin by subjecting the hemoglobin solution to an orthogonal separation methodology comprising a plurality of filtration steps. | 04-28-2011 |
Grace Simoni, Rapid City, SD US
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20150297821 | Therapeutic Compositions for Viral-Associated Disease States and Methods of Making and Using Same - A method comprising obtaining a bodily fluid from a subject; contacting the bodily fluid with an adsorbent material comprising a synthetic carbon particle (SCP) to produce a first filtrate having a level of disease mediators (y); contacting the first filtrate with an adsorbent material comprising the SCP and an anion exchange resin where the ratio of SCP to anion exchange resin is from about 0.1:100 to 100:0.1 to produce a second filtrate; contacting the second filtrate with an adsorbent material comprising the SCP and a cation exchange resin where the ratio of SCP to cation exchange resin is from about 1:100 to produce a third filtrate; and administering the third filtrate to the subject. | 10-22-2015 |
Jacquelyn Simoni, Glen Ellyn, IL US
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20110011351 | Pet Chew Toy - A pet chew toy which provides dental cleaning benefits to pets is disclosed. The pet chew toy includes a fabric covering over a central body or core. Elevated portions extend from the fabric surface and may be arranged in rows, rings, patterns, or any other decorative design. Elevated portions may be arranged to accommodate the dental structure of various types of pets. Bristles are secured to the elevated portions, and extend in a direction generally horizontal to the surface of the fabric. Bristles may be of various lengths to accommodate different sized teeth. In use, when a pet chews on the toy, the pet's teeth comes in contact with the bristles to allow the bristle to generate a brushing motion. The chew toy may include an internal compartment for holding and dispensing pet treats, and/or may include a noise making element within the chew toy to capture the pets attention. | 01-20-2011 |
20110017151 | Wound care system for pets - A wound protection system which utilizes a tubular sheath to provide coverage over an animal's injured limb. An adjustable strap extends from the tubular sheath to allow the strap to be adjusted to fit on animals of various sizes. The adjustable strap engages with the animal's collar to prevent the tubular sheath from riding down the animal's leg. The tubular sheath may have a rubber and/or water resistant region at the region of the tubular sheath in contact with an animal's paw. An interlocking mechanism along the adjustable strap allows for ease of removing the wound protection system. The tubular sheath may be equipped with additional padding, reinforcing ribs, non-stretchable strip, height adjustment mechanism, and/or a fitted region to provide various benefits to the animal. | 01-27-2011 |
Jan Simoni, Rapid City, SD US
Patent application number | Description | Published |
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20150297821 | Therapeutic Compositions for Viral-Associated Disease States and Methods of Making and Using Same - A method comprising obtaining a bodily fluid from a subject; contacting the bodily fluid with an adsorbent material comprising a synthetic carbon particle (SCP) to produce a first filtrate having a level of disease mediators (y); contacting the first filtrate with an adsorbent material comprising the SCP and an anion exchange resin where the ratio of SCP to anion exchange resin is from about 0.1:100 to 100:0.1 to produce a second filtrate; contacting the second filtrate with an adsorbent material comprising the SCP and a cation exchange resin where the ratio of SCP to cation exchange resin is from about 1:100 to produce a third filtrate; and administering the third filtrate to the subject. | 10-22-2015 |
Jan S. Simoni, Lubbock, TX US
Patent application number | Description | Published |
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20110097746 | Orthogonal Method for the Removal of Transmissible Spongiform Encephalopathy Agents from Biological Fluids - A method comprising contacting a biological fluid comprising hemoglobin and at least one pathogenic agent with a first filter and generating a first filtrate; contacting the first filtrate with a nanofiltration device and generating a second filtrate; contacting the second filtrate with a chromatographic material and isolating an eluted fraction; contacting the eluted fraction with a hydrophobic solvent and generating a hydrophobic and a hydrophilic phase; and isolating the hydrophilic phase wherein the biological fluids comprise components of interest of equal to or less than about 65 kDa. A method comprising contacting a biological fluid comprising high molecular weight components and at least one pathogenic agent with a first filter and generating a first filtrate; contacting the first filtrate with a hydrophilic membrane and generating a second filtrate; contacting the second filtrate with a chromatographic material and isolating an eluted fraction; contacting the eluted fraction with a hydrophobic solvent and generating a hydrophobic and a hydrophilic phase; and isolating the hydrophilic phase, wherein the high molecular weight components have molecular weights greater than about 65 kDa. A method comprising subjecting a biological fluid comprising hemoglobin and at least one pathogenic agent to at least two filtration steps and thereby reducing the amount of pathogenic agent associated with the biological fluid. A method comprising removing transmissible spongiform encephalopathy agents in a hemoglobin solution of human and/or animal origin by subjecting the hemoglobin solution to an orthogonal separation methodology comprising a plurality of filtration steps. | 04-28-2011 |
Michael Simoni, Huddersfield GB
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20150158317 | EXPANDED COLOR GAMUT - A method of extending the gamut of standard 4 color process printing is presented. The method thus yields various novel process printing ink sets. According to exemplary embodiments, an extended color gamut can be provided without requiring the addition of a sixth or seventh primary ink to the existing 4-color ink set. In some embodiments, an enhanced gamut can be achieved by changing the colors of the four basic primary inks and only adding a fifth primary ink. This may be done, for example, by shifting the hue of two or three of the CMY primaries and adding an additional primary. Using only five process inks thus provides, for example, the typical packaging printer with more open print stations for spot color printing or for overprint varnish application. In another illustrative embodiment, a sixth process color may be added to the inventive five color ink set. | 06-11-2015 |