Patent application number | Description | Published |
20110011127 | Process for Controlling Liquefied Natural Gas Heating Value - Process for efficiently operating a natural gas liquefaction system with integrated heavies removal/natural gas liquids recovery to produce liquefied natural gas (LNG) and/or natural gas liquids (NGL) products. | 01-20-2011 |
20110138854 | FRACTIONATION OF HYDROGEN SULFIDE RICH SOUR GAS AND METHODS OF USE - Methods and systems are provided for treating hydrogen sulfide rich sour gas through a series of fractionation columns. The processes disclosed herein and the variations thereof provide optimized processes for the removal of hydrogen sulfide from sour gas through the introduction of innovative azeotrope breakers, novel configurations of process equipment, and optimized operating conditions. Advantages of certain embodiments of the present invention include reduced equipment requirements, improved process efficiencies, reduced operating costs, and reduced capital costs. Other advantages include better process suitability to certain environmental conditions such as the arctic cold when compared to conventional amine treatment processes. | 06-16-2011 |
20120042690 | LNG FACILITY WITH INTEGRATED NGL RECOVERY FOR ENHANCED LIQUID RECOVERY AND PRODUCT FLEXIBILITY - Process for efficiently operating a natural gas liquefaction system with integrated heavies removal/natural gas liquids recovery to produce liquefied natural gas (LNG) and/or natural gas liquids (NGL) products with varying characteristics, such as, for example higher heating value (HHV) and/or propane content. Resulting LNG and/or NGL products are capable of meeting the significantly different specifications of two or more markets. | 02-23-2012 |
20140238076 | NITROGEN REJECTION UNIT - Methods and systems for removing nitrogen during liquefaction of natural are provided. Methods of removing nitrogen include warming a predominantly methane stream in a methane cold box to provide a warmed predominantly methane stream; conducting at least a portion of the warmed predominantly methane stream from the methane cold box to a nitrogen removal unit comprising at least a first nitrogen removal column and a last nitrogen removal column, wherein the first nitrogen removal column is located upstream of the last nitrogen removal column; passing the warmed predominantly methane stream through the last nitrogen removal column to provide a refluxed warmed predominantly methane stream; and routing at least a portion of the refluxed warmed predominantly methane stream to the last nitrogen removal column. | 08-28-2014 |
Patent application number | Description | Published |
20080294270 | DIFFERENTIALLY PROCESSED TISSUE AND PROCESSING METHODS THEREOF - A method of preparing an implantable biological device having a first tissue part and a second tissue part includes exposing the first tissue part to a first preparation method and preventing exposure of the second biological tissue part to the first preparation method. Preventing exposure of the second biological tissue part to the first preparation method may be achieved using an embedding technique, a coating technique, a covering technique, or physical isolation. The method may further include exposing the second tissue part to a second preparation method and preventing exposure of the first biological tissue part to the second preparation method. An apparatus for preparing an implantable biologic device includes an enclosure having first and second chambers separated by a partition member wherein a substantial portion of the first tissue part is within the first chamber and a substantial portion of the second tissue part is within the second chamber. | 11-27-2008 |
20080306610 | TISSUE PROCESSING FOR NONIMMUNOGENIC IMPLANTS - Methods for processing tissues to render them suitable for implantation, e.g. in an orthopedic site. Tissues are rendered substantially acellular and substantially nonimmunogenic by exposure to processes that result in cell lysis, increasing permeability of the extracellular matrix, degrading the debris from lysis, and removing the debris. Methods of forming tissue implants, kits for processing tissue implants, and methods of using tissue implants are also disclosed. | 12-11-2008 |
20090012629 | COMPOSITIONS AND METHODS FOR TISSUE REPAIR - Implants for repairing tissue defects, such as cartilage tissue defects, and methods of their preparation and use are disclosed. A mold of a tissue defect is prepared by pressing upon the defect a substrate having shape memory, such as aluminum foil. The mold, which has contours substantially conforming to those of the defect, is removed from the defect, and tissue particles are added to the mold ex vivo. A biological carrier such as biocompatible glue is also added to the mold. The combination of tissue particles and the biological carrier thereby form an implant, which retains its shape after separation from the mold. The implant can be transferred to the tissue defect, with contours of the mold matching corresponding contours of the defect. | 01-08-2009 |
20090030431 | MEDICAL DEVICES AND METHODS FOR CUTTING AND SUTURING BIOLOGICAL TISSUE - Medical devices for cutting and suturing biological tissue generally include a shaft and first and second guide members each including a first portion coupled to the shaft at a first location and a second portion coupled to the shaft at a second location. The first portions are movable along the shaft relative to the second portions, and the first and second guide members define an arcuate profile and are configured to flex in response to such movement. When used to cut tissue, the medical device may further include a blade positioned between the first and second guide members. When used to suture tissue, one or more suture guides may be provided on the first guide member for directing a suture needle through tissue proximate the first guide member. Methods of repairing and replacing a meniscus using the medical devices are also provided. | 01-29-2009 |
20100191281 | Apparatus and Method for Delivering a Biocompatible Material to a Surgical Site - A device for delivering a biocompatible material to a surgical site includes a cannula having proximal and distal portions and at least a first interior lumen disposed therebetween through which the biocompatible material is delivered. The device further includes an initiation member for initiating cross-linking of the biocompatible material while the biocompatible material is within the cannula. The cannula may include a heating element to thermally initiate cross-linking. Alternately, the cannula may include a second lumen for transmitting light from a light source. A movable blocking element controls the amount of light that passes into the first lumen. A method of delivering a curable biocompatible material to a surgical site includes positioning a distal portion of a cannula adjacent the surgical site and introducing the biocompatible material through a first lumen of the cannula. Cross-linking of the biocompatible material is then initiated while the biocompatible material is within the cannula. | 07-29-2010 |
20100297766 | Method of Removing Undesired Tissue from Connective Tissue - A method of removing undesired tissue from a connective tissue is provided that includes stretching the connective tissue and peeling away the undesired tissue. Some methods include soaking the connective tissue in a solution prior to and/or subsequent to stretching and peeling away the undesired tissue. The solution may include a detergent, an enzyme, a salt solution, an organic solvent, and combinations thereof. | 11-25-2010 |
20110110888 | Scaffold Coated and/or Impregnated with at Least One Bioactive Agent for Tissue Repair and Other Medical Applications - A system and method for producing a scaffold coated and/or impregnated with at least one bioactive agent. This is accomplished by culturing at least one cell in the same medium as a scaffold, but without physical contact between the at least one cell and the scaffold. The system includes a container having a surface defining an interior compartment. A medium is disposed within the interior compartment. At least one cell is disposed within the medium, the at least one cell being capable of producing at least one bioactive agent. Further, a scaffold is disposed within the medium. The scaffold is physically separated from the at least one cell such that there is no contact between the scaffold and the at least one cell. Thus, as the at least one cell produces at least one bioactive agent, such as a growth factor, the at least one bioactive agent enters the medium, and contacts and coats and/or impregnates the scaffold. However, due to the physical separation of the scaffold and at least one cell, the at least one cell is prevented from contacting and coating and/or impregnating the scaffold. Thus, only the desired bioactive agent or agents coat and/or impregnate the scaffold. | 05-12-2011 |
20120107384 | APPARATUS FOR FORMING AN IMPLANT - Implants for repairing tissue defects, such as cartilage tissue defects, and methods of their preparation and use are disclosed. A mold of a tissue defect is prepared by pressing upon the defect a substrate having shape memory, such as aluminum foil. The mold, which has contours substantially conforming to those of the defect, is removed from the defect, and tissue particles are added to the mold ex vivo. A biological carrier such as biocompatible glue is also added to the mold. The combination of tissue particles and the biological carrier thereby form an implant, which retains its shape after separation from the mold. The implant can be transferred to the tissue defect, with contours of the mold matching corresponding contours of the defect. | 05-03-2012 |
Patent application number | Description | Published |
20100301849 | NOVEL SCANNING MAGNETIC IMAGING METHOD WITH HIGH RESOLUTION AND LONG DETECTION RANGE - A method of magnetic imaging at long detection ranges. In one embodiment the method comprises introducing a magnetic sample having magnetic particles into a detection field; detecting weak magnetic field signals of the magnetic particles; forming an image from the detected signals; and determining the location and quantity amount of the magnetic particles. The method further comprises introducing a magnetic sample to a human or other organism's body. | 12-02-2010 |
20120020892 | FORCE-INDUCED MAGNETIZATION CONTRAST FOR DIAGNOSIS AND IMAGING - A method of detecting target molecules comprising; conjugating a first magnetic particle to a first ligand to form a first magnetic particle ligand conjugate; adding the conjugate to a sample containing target molecules to form a mixture comprising, the free conjugate and conjugate-target molecule binding pairs; measuring a first magnetization of the mixture; subjecting the mixture to a first force; measuring a second magnetization value of the mixture; subtracting the second magnetization value from the first magnetization value to calculate a first force-induced magnetization contrast; subjecting the mixture to a second force; measuring a third magnetization of the mixture; and subtracting the third magnetization value from the second magnetization value to calculate a second force-induced magnetization contrast. | 01-26-2012 |
20140309134 | EXCHANGE-INDUCED REMNANT MAGNETIZATION FOR LABEL-FREE DETECTION OF DNA, MICRO-RNA, AND DNA/RNA-BINDING BIOMARKERS - A method of using an exchange-induced remnant magnetization (EXIRM) technique for label free detection of short strands of nucleotides and cancer biomarkers, such as DNA and microRNA strands, DNA/RNA-binding biomarkers, and cancer-specific antigens, with high sensitivity, high specificity, and broad dynamic range. The method may provide a label-free approach aimed to facilitate high reliability, and to require a minimum amount of biochemical reagents. | 10-16-2014 |
Patent application number | Description | Published |
20090299257 | REDUCED-PRESSURE SURGICAL WOUND TREATMENT SYSTEMS AND METHODS - A reduced-pressure system for treating tissue, such as damaged subcutaneous tissue, includes a shaped dressing bolster for placing on the patient's epidermis and substantially sized to overlay the damaged subcutaneous tissue. The system further includes a sealing subsystem for providing a fluid seal over the shaped dressing bolster and a portion of the patient's epidermis, and a reduced-pressure subsystem for delivering a reduced pressure to the sealing subsystem. The reduced-pressure system may develop a force, which may include a vertical force that is realized at tissue site deeper than the epidermis or a closing force directed towards the incision. The shaped dressing bolster is shaped to evenly distribute the force. Other methods and systems are included. | 12-03-2009 |
20090299341 | DRESSING ASSEMBLIES FOR WOUND TREATMENT USING REDUCED PRESSURE - A dressing assembly for use with a reduced pressure treatment system, the dressing assembly develops a directed force under reduced pressure. The directed force may be a radial force or a closing force. The dressing assembly includes a shaped dressing bolster having a shaped extremity that is operable to evenly deliver the radial force and to distribute reduced pressure. Numerous shapes may be used for the shaped extremity. The dressing assembly may further include an over-drape to assist in creating a seal over the shaped dressing bolster and against a portion of a patient's epidermis. | 12-03-2009 |
20110092927 | DRESSING REDUCED-PRESSURE INDICATORS, SYSTEMS, AND METHODS - Dressings, systems, and methods are disclosed in some embodiments that involve treating a tissue site with reduced pressure wherein the dressing includes a dressing reduced-pressure indicator that allows one to ascertain that the reduced pressure applied at the dressing is greater than a threshold reduced pressure. The dressing reduced-pressure indicator may include a moving member that is adapted to move under reduced pressure and a visual indicator associated with the moving member. Another embodiment uses an electro-mechanical indicator to provide a powered visual alert or audible alert or another output signal. Other dressings, systems, and methods are disclosed. | 04-21-2011 |
20120220964 | DRESSING ASSEMBLIES FOR WOUND TREATMENT USING REDUCED PRESSURE - A dressing assembly for use with a reduced pressure treatment system, the dressing assembly develops a directed force under reduced pressure. The directed force may be a radial force or a closing force. The dressing assembly includes a shaped dressing bolster having a shaped extremity that is operable to evenly deliver the radial force and to distribute reduced pressure. Numerous shapes may be used for the shaped extremity. The dressing assembly may further include an over-drape to assist in creating a seal over the shaped dressing bolster and against a portion of a patient's epidermis. | 08-30-2012 |
20130324953 | DRESSING REDUCED-PRESSURE INDICATORS, SYSTEMS, AND METHODS - Dressings, systems, and methods are disclosed, in some embodiments, that involve treating a tissue site with reduced pressure, wherein the dressing includes a dressing reduced-pressure indicator that allows one to ascertain that the reduced pressure applied at the dressing is greater than a threshold reduced pressure. The dressing reduced-pressure indicator may include a moving member that is adapted to move under reduced pressure and a visual indicator associated with the moving member. Another embodiment uses an electro-mechanical indicator to provide a powered visual alert or audible alert or another output signal. Other dressings, systems, and methods are disclosed. | 12-05-2013 |
20140012213 | RELEASABLE MEDICAL DRAPES - A releasable medical drape, and systems and methods having the same, includes at least a liquid-impermeable, vapor-permeable layer, a pressure-sensitive adhesive layer, and a soft-gel layer having a plurality of apertures. The soft-gel layer is configured to be disposed adjacent to a tissue site. A portion of the pressure-sensitive adhesive layer extends through the plurality of apertures in the soft-gel layer to contact the tissue site. The soft-gel layer forms a good seal with the tissue site and the pressure-sensitive adhesive layer extending through the plurality of apertures forms a firm—but releasable—coupling with the tissue site. | 01-09-2014 |
20140194836 | DRESSING ASSEMBLIES FOR WOUND TREATMENT USING REDUCED PRESSURE - A dressing assembly for use with a reduced pressure treatment system, the dressing assembly develops a directed force under reduced pressure. The directed force may be a radial force or a closing force. The dressing assembly includes a shaped dressing bolster having a shaped extremity that is operable to evenly deliver the radial force and to distribute reduced pressure. Numerous shapes may be used for the shaped extremity. The dressing assembly may further include an over-drape to assist in creating a seal over the shaped dressing bolster and against a portion of a patient's epidermis. | 07-10-2014 |
Patent application number | Description | Published |
20100047277 | VIROSOMES, METHODS OF PREPARATION, AND IMMUNOGENIC COMPOSITIONS - Briefly described, virosomes, methods of preparing virosomes, immunogenic compositions that include virosomes, and methods of eliciting an immune response using immunogenic compositions that include virosomes are described herein. A virosome can include at least one viral surface envelope glycoprotein expressed on the surface of the virosome. The virosome can also optionally include at least one adjuvant molecule expressed on the surface of the virosome. | 02-25-2010 |
20130121912 | MICRORNA-198 AS A TUMOR SUPPRESSOR IN PANCREATIC CANCER - A novel network of tumorigenic prognostic factors is identified that plays a critical role in advanced pancreatic cancer (PC) pathogenesis. This interactome is interconnected through a central tumor suppressive microRNA, miR-198, which is able to both directly and indirectly modulate expression of the various members of this network to alter the molecular makeup of pancreatic tumors. When this tumor signature network is intact, miR-198 expression is reduced and patient survival is dismal; patients with higher miR-198 present an altered tumor signature network, better prognosis and increased survival. Further, MiR-198 replacement reverses tumorigenicity in vitro and in vivo. embodiment of the disclosure is a method of treating cancer in an individual, comprising the step of increasing the level of active microRNA-198 molecules in the pancreatic cancer tumor cells of the individual by an amount sufficient to cause an improvement in the pancreatic cancer in the individual. | 05-16-2013 |
20130259926 | BI-FUNCTIONAL shRNA TARGETING MESOTHELIN AND USES THEREOF - The present invention includes bifunctional shRNAs capable of reducing an expression of a Mesothelin gene; wherein at least one target site sequence of the bifunctional RNA molecule is located within the Mesothelin, wherein the bifunctional RNA molecule is capable of activating a cleavage-dependent and a cleavage-independent RNA-induced silencing complex for reducing the expression level of Mesothelin. | 10-03-2013 |
20130295160 | ANTAGONISTS OF MIR-196A - A miR-196a antagonist capable of inhibiting a miR-196a activity, the miR-196a antagonist comprising one or more target sites for miR-196a. Included is also an expression vector comprising a promoter and a nucleic acid insert operably linked to the promoter, wherein the insert encodes one or more miR-196a antagonists capable of inhibiting a miR-196a activity. In one example, the one or more miR-196a antagonists comprise at least one stem-loop structure comprising a guide strand that comprises a sequence that is complementary to miR-196a, the stem-loop structure further comprising a passenger strand that comprises a mismatch. | 11-07-2013 |
20140163045 | Small Molecule Xanthine Oxidase Inhibitors and Methods of Use - Small molecule xanthine oxidase inhibitors are provided, as well as methods for their use in treating gout or hyperuricemia. | 06-12-2014 |
20140329909 | SMALL MOLECULE XANTHINE OXIDASE INHIBITORS AND METHODS OF USE - Small molecule xanthine oxidase inhibitors are provided, as well as methods for their use in treating gout or hyperuricemia. | 11-06-2014 |
20140336204 | METHODS OF INHIBITING XANTHINE OXIDASE ACTIVITY IN A CELL - Small molecule xanthine oxidase inhibitors are provided, as well as methods for their use in treating gout or hyperuricemia. | 11-13-2014 |
20140336205 | Small Molecule Xanthine Oxidase Inhibitors and Methods of Use - Small molecule xanthine oxidase inhibitors are provided, as well as methods for their use in treating gout or hyperuricemia. | 11-13-2014 |
20140364508 | Small Molecule Xanthine Oxidase Inhibitors and Methods of Use - Small molecule xanthine oxidase inhibitors are provided, as well as methods for their use in treating gout or hyperuricemia. | 12-11-2014 |
20140378478 | Small Molecule Xanthine Oxidase Inhibitors and Methods of Use - Small molecule xanthine oxidase inhibitors are provided, as well as methods for their use in treating gout or hyperuricemia. | 12-25-2014 |
20140378552 | Small Molecule Xanthine Oxidase Inhibitors and Methods of Use - Small molecule xanthine oxidase inhibitors are provided, as well as methods for their use in treating gout or hyperuricemia. | 12-25-2014 |
20150211009 | MICRORNA-198 AS A TUMOR SUPPRESSOR IN PANCREATIC CANCER - A novel network of tumorigenic prognostic factors is identified that plays a critical role in advanced pancreatic cancer (PC) pathogenesis. This interactome is interconnected through a central tumor suppressive microRNA, miR-198, which is able to both directly and indirectly modulate expression of the various members of this network to alter the molecular makeup of pancreatic tumors, with important clinical implications. When this tumor signature network is intact, miR-198 expression is reduced and patient survival is dismal; patients with higher miR-198 present an altered tumor signature network, better prognosis and increased survival. Further, according to the present disclosure, MiR-198 replacement reverses tumorigenicity in vitro and in vivo. As such, an embodiment of the disclosure is a method of treating cancer in an individual, comprising the step of increasing the level of active microRNA-198 molecules in the pancreatic cancer tumor cells of the individual by an amount sufficient to cause an improvement in the pancreatic cancer in the individual | 07-30-2015 |
20150266929 | VIRUS-LIKE PARTICLES, METHODS OF PREPARATION, AND IMMUNOGENIC COMPOSITIONS - Briefly described, virus-like particles, methods of preparing virus-like particles, immunogenic compositions that include virus-like particles, and methods of eliciting an immune response using immunogenic compositions that include virus-like particles are described herein. A virus-like particle (VLP) can include a viral core protein that can self assemble into the VLP core and at least one viral surface envelope glycoprotein expressed on the surface of the VLP. The VLP can also optionally include at least one adjuvant molecule expressed on the surface of the VLP. | 09-24-2015 |
20150353471 | XANTHINE OXIDASE INHIBITORS AND METHODS OF USE - Small molecule xanthine oxidase inhibitors are provided, as well as compositions, methods for their use for treating disorders, mediated at least in part, by xanthine oxidase. | 12-10-2015 |
Patent application number | Description | Published |
20130054863 | Resource Manager, System And Method For Communicating Resource Management Information For Smart Energy And Media Resources - According to an aspect of the disclosure, a resource management platform, system and method of communicating resource management information for smart energy and media resources is provided. A resource management platform can include an interface configured to communicate media management information and energy management information. The resource management platform also includes a processor configured to detect an incoming communication to alter an operating condition in response to receiving the media management information or the energy management information. The processor can further be configured to initiate an output of media content in response to detecting media management information, and initiate altering an operating status of a device in response to detecting the energy management information. The processor can also initiate storing at least a portion of the media content and the energy management information within a memory. | 02-28-2013 |
20140060876 | TERMINAL CONNECTOR FOR A WALL MOUNTED DEVICE - A wall mounted device includes a housing having a rear surface that is intended to face a wall to which the device is to be mounted. The housing also has an interior portion and an opening formed therein to allow wires from the wall to pass therethrough for communication with the interior housing. The opening has a center point. At least one terminal block may be disposed in the interior portion of the housing and includes a plurality of terminals that are configured to engage a wire to form an electrical connection. Each of the plurality of terminals can be located equidistant from a point within the opening such that the lengths of wire in the housing are reduced. | 03-06-2014 |
20150019736 | RESOURCE MANAGER, SYSTEM, AND METHOD FOR COMMUNICATING RESOURCE MANAGEMENT INFORMATION FOR SMART ENERGY AND MEDIA RESOURCES - According to an aspect of the disclosure, a resource management platform, system and method of communicating resource management information for smart energy and media resources is provided. A resource management platform can include an interface configured to communicate media management information and energy management information. The resource management platform also includes a processor configured to detect an incoming communication to alter an operating condition in response to receiving the media management information or the energy management information. The processor can further be configured to initiate an output of media content in response to detecting media management information, and initiate altering an operating status of a device in response to detecting the energy management information. The processor can also initiate storing at least a portion of the media content and the energy management information within a memory. | 01-15-2015 |
Patent application number | Description | Published |
20140308581 | Aqueous Energy Storage Devices with Organic Electrode Materials - An aqueous metal-ion battery and a method for constructing same. In one embodiment, the battery includes an aqueous electrolyte and at least one electrode comprising at least one organic electrode material. A method comprises incorporating an organic electrode material into the electrode of an aqueous metal-ion battery. The organic electrode material further comprises at least one material chosen from carbonyl compounds. | 10-16-2014 |
20140335407 | Non-Lithium Metal Ion Battery Electrode Material Architecture - A method for configuring a non-lithium-intercalation electrode includes intercalating an insertion species between multiple layers of a stacked or layered electrode material. The method forms an electrode architecture with increased interlayer spacing for non-lithium metal ion migration. A laminate electrode material is constructed such that pillaring agents are intercalated between multiple layers of the stacked electrode material and installed in a battery. | 11-13-2014 |
20160049659 | RECHARGEABLE ALKALINE BATTERY USING ORGANIC MATERIALS AS NEGATIVE ELECTRODES - An energy storage device may provide a positive electrode, an electrolyte, and a negative electrode. The energy storage device may utilize an aqueous alkaline electrolyte, which may be nonflammable. The energy storage device may utilize organic material(s) as the negative electrode, such as, but not limited to, poly(anthraquinonyl sulfide) (PAQS), organic carbonyl compounds, organosulfur compounds, redox polymers, or radical polymers. | 02-18-2016 |