Shamay
Ezra Shamay, Qiryat Bialik IL
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20150035974 | COMBINED IMAGER AND RANGE FINDER - combined imager and rangefinder includes an imaging sensor and an illuminator. The sensor acquires images of objects in a FOV. The illuminator directs a beam of light via the FOV. In a first mode, the sensor acquires full images of the whole FOV. In a second mode, the sensor acquires partial images, of only part of the FOV, that include a reflection of the light from one of the objects. The range to the object is determined from the location of the reflection in the partial images. Successive range measurements are used to determine whether a collision with the object is imminent. | 02-05-2015 |
Gershon Shamay, Irvine, CA US
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20100064763 | WEB-BASED SYSTEM AND METHOD FOR CONFIGURING TEST EQUIPMENT - A web-based system and method for configuring test equipment is provided. In one aspect, the invention provides a method for configuring a test instrument, the method including receiving a first configuration file previously generated by a web server, the first configuration file including information indicative of a configuration including at least one component for the test instrument, providing a user interface enabling modification of the configuration of the at least one component and the test instrument, and generating a second configuration file including information indicative of the modified configuration. | 03-18-2010 |
Meir Shamay, Baltimore, MD US
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20140235484 | METHODS FOR DETECTION AND DIFFERENTIATION OF ORIGIN OF VIRAL DNA - The invention disclosed herein provides methods for identifying the origin of viral DNA in a sample by detecting the methylation state of at least one CpG site on a target site of the genome of a virus of interest, and determining whether the origin of the viral DNA is from a cell, such as a tumor cell, or a virion, wherein when the methylation state is positive for methylation, the viral DNA is from a cell, and wherein when the methylation state is negative for methylation, the viral DNA is from a virion. Use of these methods for diagnosis or monitoring, and/or treatment of a subject infected with a virus known to cause cancer and related disease are also provided. | 08-21-2014 |
Noam Shamay, Rehovot IL
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20110071435 | Method and System for Coupling an Extension Wire to a Guidewire - A method and a system using a helicoidal structure wound out of a plurality of metallic wires into a universal connector for reversibly coupling a distal end portion of an extension wire to a proximal end portion of a guide wire. The universal connector is configured for receiving the proximal end portion of the guide wire into the connector lumen and is made as a single-piece unit built to sustain increased separation forces tending to disconnect the extension wire from the guide wire. The universal connector accommodates coupling to different configurations of commercially available guide wire proximal terminations. | 03-24-2011 |
Noam Shamay, Moshav Ptachia IL
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20110009889 | BLOOD VESSEL OCCLUSION AUGER - A blood occlusion auger having an in vivo distal auger tool coupled in operative association with an ex vivo auger control for opening and traversing occlusions in a blood vessel The auger control allows the selection of predetermined threshold forces and step-lengths values and operates in successive repetition of identical sequential stages, to traverse occlusions. Once disposed adjacent an occlusion, the auger tool, commanded by the auger control, operates in two states, first to radially dilate the vessel and second to penetrate distally into a furrow. | 01-13-2011 |
Noam Shamay, Beit Uziel IL
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20140222062 | METHOD, SYSTEM, AND FASTENER FOR ANCHORING A CORPUS - There is described a method, a system, and a device for the anchoring of and into a corpus disposed distally in a conduit by engaging a stranded tube with the corpus and unwinding the wound threads of the stranded tube into unwound threads. Engagement includes the use of handling and manipulation shaft to dispose the stranded tube proximally, distally, or in the interior to the corpus. Unwinding, of the stranded tube is achieved by rotating a tube tool against the stranded tube. Unwinding liberates the helically coiled unwound strands in “corkscrew” rotation into the corpus. Proximal retrieval of a corpus is achieved by proximal retrieval of the stranded tube anchoring the corpus. An unwound stranded tube is operable as a fastener, as an electrical lead, and as a support for a device. | 08-07-2014 |
Sagie Shamay, Kibbutz Mishmarot IL
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20150071607 | EFFICIENT CONTENT BASED VIDEO RETRIEVAL - Various disclosed embodiments relate to video content analysis based in part upon the detection of shot transitions. In some embodiments, a process and computer system for detecting shot transitions in a video is used to separate a video sequence into a series of “shots” having multiple frames. These shots may then be used for additional processing, e.g., content detection within the video frames. | 03-12-2015 |
Yosef Shamay, New York, NY US
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20150328254 | FUCOIDAN NANOGELS AND METHODS OF THEIR USE AND MANUFACTURE - Described herein are polymeric drug-carrying nanogels that are capable of targeting to P-selectin for the treatment of cancer and other diseases and conditions associated with P-selectin. Furthermore, in certain embodiments, the nanogels presented here offer a drug release mechanism based on acidic pH in the microenvironment of a tumor, thereby providing improved treatment targeting capability and allowing use of lower drug doses, thereby reducing toxicity. | 11-19-2015 |
Yosi Shamay, Kfar Sabbah IL
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20120014904 | VASCULAR DELIVERY SYSTEMS - The site-specific expression of selectins on endothelial cells of blood vessels during angiogenesis provides an opportunity to target anti-cancer drugs to the vascular endothelium to extend the range of the therapeutic effect. This invention describes an innovative drug targeting strategy for the selective delivery of the anticancer drugs to endothelial cells by means of polymer-drug conjugates modified with a carbohydrate ligand for the vascular selectins. A model chemotherapeutic drug, doxorubicin, and the E-selectin ligand, sLex, are attached to a biocompatible polymer (HPMA). The selective binding, cellular uptake, intracellular fate, and cell cytotoxicity of the polymer-bound drug are investigated in human endothelial cells. | 01-19-2012 |
20150056157 | VASCULAR DELIVERY SYSTEMS - The site-specific expression of selectins on endothelial cells of blood vessels during angiogenesis provides an opportunity to target anti-cancer drugs to the vascular endothelium to extend the range of the therapeutic effect. This invention describes an innovative drug targeting strategy for the selective delivery of the anticancer drugs to endothelial cells by means of polymer-drug conjugates modified with a carbohydrate ligand for the vascular selectins. A model chemotherapeutic drug, doxorubicin, and the E-selectin ligand, sLex, are attached to a biocompatible polymer (HPMA). The selective binding, cellular uptake, intracellular fate, and cell cytotoxicity of the polymer-bound drug are investigated in human endothelial cells. | 02-26-2015 |
Yossi Shamay, Kfar Sabbah IL
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20140017169 | CAGED CELL PENETRATING PEPTIDE-POLYMER CONJUGATES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS - The caged cell-penetrating peptide (cCPP) conjugates of this invention are ideal for intracellular delivery of a broad variety of cargoes including various nanoparticulate pharmaceutical carriers (liposomes, micelles, microparticles, nanoparticles, polymer-conjugates). The conjugates comprise a detectable agent or a therapeutic agent, and the conjugates provide a novel strategy for site-specific delivery of the same to appropriate tissues in the subject. Versatile application of the conjugates in diagnostics and imaging is described. | 01-16-2014 |