Ringler, US
Daniel R. Ringler, Elizabethville, PA US
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20080293272 | TWO PIECE SINGLE USE SECURITY MODULE MEZZANINE CONNECTOR - A connector assembly including a modified contact is disclosed for connecting a first electrical device to a second electrical device. In a first embodiment, the connector assembly includes a tool necessary to press-fit the connector to the second electrical device. In a second embodiment, the connector assembly includes two connectors that mate in such a manner so as to render the modified contact unusable if the two connectors are unmated. | 11-27-2008 |
Daniel Robert Ringler, Elizabethville, PA US
Patent application number | Description | Published |
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20080318448 | DIMM SOCKET POSITIVE LOCK EXTRACTOR - A card edge connector including a housing and a pair of extractors is disclosed for electrically connecting a first PCB such as a daughter card to a second PCB such as a motherboard. The extractors both secure and eject the daughter card from the connector. The extractors may be configured to reduce micro-motion of the daughter card by applying a vertical downward force thereto. | 12-25-2008 |
20090023332 | Electrical connector assembly with shorting contacts - An electrical connector assembly is provided. The electrical connector assembly includes a housing including a body fabricated at least partially from a dielectric material. The housing body has an opening therein. An electrical contact is held by the housing. The electrical contact includes an intermediate portion and a spring portion each held at least partially within the opening. The spring portion of the electrical contact is engaged by the housing body such that the spring portion is deflected into shorting engagement with the intermediate portion of the electrical contact. | 01-22-2009 |
20100093194 | CONNECTOR ASSEMBLY WITH VARIABLE STACK HEIGHTS HAVING POWER AND SIGNAL CONTACTS - A connector assembly includes a housing, a signal contact and a power contact. The housing has a mounting body and a mating body coupled together and separated by a gap. The gap permits air to flow between the lower and mating bodies. The mating body is configured to engage an upper substrate and the mounting body is configured to engage a lower substrate to mechanically interconnect the upper and lower substrates. The signal contact extends between and protrudes from the mating and mounting bodies and is configured to communicate a data signal between the mating and mounting bodies. The power contact extends between and protrudes from the mating and mounting bodies and is configured to communicate electrical power between the upper and lower substrates. The housing separates the upper and lower substrates by a predetermined stack height. | 04-15-2010 |
20100093232 | RECEPTACLE CONTACT WITH A WIDENED MATING TIP - A receptacle connector includes a housing and a receptacle contact. The housing includes a cavity extending through the housing from the mating side to the mounting side. The receptacle contact is disposed within the cavity and is configured to receive a mating contact of the mating connector. The receptacle contact includes elongated shafts disposed on opposite sides of a longitudinal axis and mating tips coupled to the shafts. The mating tips have tapered shapes between the shafts and outer ends of the mating tips. The tapered shapes are wider than the shafts in a lateral direction that is transverse to the longitudinal axis. The receptacle contact is configured to receive a mating contact of a mating connector between the mating tips to electrically couple the mating connector with the receptacle connector. | 04-15-2010 |
20100178808 | ELECTRICAL CONNECTOR FOR ELECTRONIC MODULES - An electrical contact includes a body extending along a longitudinal axis. The body includes a mating contact portion for electrical connection with an electronic module, an intermediate portion extending from the mating contact portion, and a mounting contact portion extending from the intermediate portion for electrical connection with a circuit board. The mounting contact portion extends from the intermediate portion at a bend. The mounting contact portion extends from the bend to an end portion. The body also includes a push surface formed when a carrier strip that initially connects the electrical contact to other electrical contacts is separated from the electrical contact. The push surface is offset from the bend along the longitudinal axis in a direction away from the mating contact portion. | 07-15-2010 |
Douglas Ringler, Boston, MA US
Patent application number | Description | Published |
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20110008330 | Compositions and methods of tolerizing a primate to an antigen - Inducing tolerance in a primate by use of a compound, or a combination of at least two compounds, that has certain characteristics when tested in vitro. The compound, alone or in combination, is preferably TRX1 antibody and the compound or combination is preferably used in accordance with a specified dosing regimen. | 01-13-2011 |
20120269826 | ANTI-CD3 ANTIBODY DOSING IN AUTOIMMUNE DISEASE - Provided herein are methods of administering anti-CD3 antibodies or antigen-binding fragments thereof to an animal. In certain embodiments, the anti-CD3 antibody or fragment thereof does not bind or has reduced binding to at least one class of Fc (gamma) receptors. In certain embodiments, the animal has an immune-related disease. | 10-25-2012 |
20130171142 | METHODS OF USING ANTI-CD3 ANTIBODIES TO PREVENT WEIGHT GAIN - Provided herein are methods of administering anti-CD3 antibodies or antigen binding fragments to a human for decreasing weight gain or increasing weight loss. In certain embodiments, the human exhibits a body mass index (BMI) or greater than or equal to about 27. In certain embodiments, the anti-CD3 antibody or antigen binding fragment does not bind or has reduced binding to at least one class of Fc (gamma) receptor. | 07-04-2013 |
Douglas J. Ringler, Revere, MA US
Patent application number | Description | Published |
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20090011464 | Humanized immunoglubulin reactive with alph4beta7 integrin - The present invention relates to isolated nucleic acids encoding humanized immunoglobulins having binding specificity for α4β7 integrin, isolated nucleic acids encoding a humanized immunoglobulin heavy chain and isolated nucleic acids encoding a humanized light chain having binding specificity for α4β7 integrin. The invention also relates to expression vectors and host cells comprising a nucleotide sequence which encodes a humanized immunoglobulin or antigen-binding fragment thereof having binding specificity for α4β7. The invention further relates to methods of preparing a humanized immunoglobulin, humanized immunoglobulin heavy chain and humanized immunoglobulin light chain that has binding specificity for α4β7 integrin. | 01-08-2009 |
20090110659 | Human chemotactic cytokine - The invention relates to isolated and/or recombinant nucleic acids which encode a human chemotactic cytokine designated human eotaxin, and to isolated and/or recombinant human eotaxin proteins or polypeptides, including synthetic polypeptides. The invention further relates to recombinant nucleic acid constructs, comprising a nucleic acid which encodes a human eotaxin, a portion thereof, or a variant; to host cells comprising such constructs, useful for the production of recombinant human eotaxin; and to antibodies reactive with human eotaxin, useful in in vitro methods, diagnosis and/or therapy. Also provided are methods of use of the eotaxin proteins, e.g., in the recruitment of eosinophils to a particular site or in the treatment of allergic conditions. Human eotaxins can be used to identify inhibitors (e.g., antagonists) or promoters (agonists) of human eotaxin, which can be used to selectively modulate leukocyte function, in inflammatory and autoimmune diseases, or in infections. | 04-30-2009 |
Richard B. Ringler, Middletown, CT US
Patent application number | Description | Published |
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20080308958 | Method of determining depth of intergranular attack (IGA) for a metal part - A method of determining a depth of intergranular attack (IGA) on a surface of a metal part includes applying a replicating material on a second surface of the part that is essentially perpendicular to and intersects with the surface of interest. The replicating material is used to create an inverted replica of the microstructure of the second surface. Lengths of the cracks replicated on the replicating material are measured in order to determine the depth of intergranular attack on the surface of the part. In some embodiments, a fixture device may be temporarily attached to the metal part to maintain an edge of the second surface. | 12-18-2008 |
20110177285 | REPAIR OF COMPOSITE SANDWICH STRUCTURES - A method of restoring a section of a composite includes the steps of removing an undesirable section of a composite and securing a repair section in the location of the removed undesirable section. One or more covers are secured on at least a portion the repair section to prevent or resist peeling of the repair section. | 07-21-2011 |