Iulian
Iulian Alecu, Paris FR
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20090055378 | SYSTEMS AND METHODS FOR PROVIDING IMPROVED ACCESS TO PHAMACOVIGILANCE DATA - A system and method for browsing a pharmacovigilance database with a graphical representation that shows relationships between medical terms may include providing access to a plurality of medical terminologies and mapping medical terms of the plurality of terminologies to a searchable database by using a semantic network to relate the medical terms of the different terminologies. The system and method may further include providing a graphical user interface that enables graphical navigation of the plurality of terminologies, enables display of a mapping between a first medical term from a first medical terminology to a second medical term from a second medical terminology, and enables coding of pharmacovigilance reports using medical terms of the second terminology based on a description provided using medical terms of the first terminology. | 02-26-2009 |
Iulian Bobe, Chiba JP
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20100298495 | BLOCK COPOLYMER FOR DRUG CONJUGATES AND PHARMACEUTICAL COMPOSITION - The present invention provides a block copolymer for a drug conjugate which comprises a water-soluble polymer region consisting of polyethylene glycol and a polyamino acid region having a hydrazide group and a hydrophobic group in the side chain. | 11-25-2010 |
20100310497 | PHARMACEUTICAL COMPOSITION OR COMBINATION DRUG - A pharmaceutical composition or combination drug, which contains, as active ingredients, (a) a coordination compound composed of a block copolymer represented by the following formula I or formula II and cisplatin, and (b) gemcitabine hydrochloride. | 12-09-2010 |
Iulian Bobe, Danville, VA US
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20140331993 | GREEN PROCESS TO HYDROLYZE CARBOHYDRATES FROM TOBACCO BIOMASS USING SUBCRITICAL WATER - Processes for recovering sugars and nicotine from a tobacco biomass include feeding a biomass of tobacco plants and subcritical water to a reactor, hydrolyzing the biomass of tobacco plants with the subcritical water at a temperature between about 150° C. and 305° C. and recovering a liquid product and a solid product from the reactor, wherein the liquid product contains water-soluble sugars and nicotine. | 11-13-2014 |
20150344978 | NICOTINE RESISTANT MICROORGANISMS - Compositions and methods are provided for enhanced production of ethanol from fermentation of tobacco biomass. Nicotine resistant microorganisms are provided, as well as methods for making these nicotine resistant microorganisms. A biologically pure culture is provided of a nicotine resistant | 12-03-2015 |
Iulian Cioanta, Milton, GA US
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20140088465 | Extracorporeal Pressure Shock Wave Devices with Reversed Applicators and Methods for Using these Devices - A shock wave applicator includes a shock wave generator and an asymmetrical reflector portion in a housing. Asymmetry of the reflector portion is combined with one or more wave generators to produce a variety of focal volumes and wave fronts for medical treatment. | 03-27-2014 |
20140212330 | METHODS FOR CLEANING AND STERILIZATION OF IMPLANT TISSUE EX VIVO WITH SHOCK WAVES - This invention includes methods for cleaning and sterilizing tissue harvested for implant with shock waves by submerging the harvested tissue in a volume of fluid in a holding vessel including a shock wave applicator with a focal volume in the volume of fluid, and applying a pressure shock wave pulses to the harvested tissue from the shock wave applicator in sufficient amounts to eliminate biological contaminants in the harvested tissue. | 07-31-2014 |
20140212554 | METHODS FOR CLEANING AND TENDERIZING ANIMAL MEAT WITH SHOCK WAVES - This invention includes methods for cleaning and tenderizing animal meat with shock waves by submerging animal meat in a volume of fluid in a treatment tank including a shock wave applicator with a focal volume in the volume of fluid, and applying a pressure shock wave pulses to the animal meat from the shock wave applicator in sufficient amounts to eliminate biological contaminants and/or tenderize the animal meat. | 07-31-2014 |
20140243715 | Extracorporeal Pressure Shock Wave Devices with Multiple Reflectors and Methods for Using these Devices - A shock wave applicator includes a housing multiple reflectors with shock wave generators projecting into a shared cavity. The multiple shock wave generators are able to produce a variety of shockwave focal volumes and wave fronts for medical treatment. | 08-28-2014 |
20140305877 | APPARATUSES AND METHODS FOR GENERATING SHOCK WAVES FOR USE IN THE ENERGY INDUSTRY - Several methods and devices are provided herein to generate shock waves that are used in the oil industry for well drilling, hydrocarbon or gas exploitation, fracking process or improved oil recovery (IOR), enhanced oil recovery (EOR), cleaning of process waters, oil spills byproducts and oil pipes, which can be used as independent systems or as auxiliary systems concomitantly with other existing technologies. The different devices consist of generating shock waves utilizing either one or more laser sources, or a self-generated combustible gas supply, or a micro-explosive pellet, or piezocrystals, or a piezofiber composite structure. | 10-16-2014 |
20150337630 | SHOCK WAVES FOR PIPE CLEANING - A pipe cleaning apparatus includes a shock wave generating device of a shock wave module and a traction module with rollers connected to the shock wave module. The modules are connected by a joint permitting maneuverability around pipe bends. | 11-26-2015 |
20160000645 | Shock Wave Applicator with Movable Electrode - A shock wave applicator includes a reflector and a movable shockwave-generating electrode disposed in the reflector at a first focal point. The reflector is at least a portion of an ellipsoidal shape having a long and small axis with the first focal point and a second focal point on the long axis, and the reflector terminates at an edge defining a membrane-covered aperture on a plane intersecting the small axis and coincident with the second focal point. | 01-07-2016 |
20160022294 | OCCLUSION AND CLOT TREATMENT WITH INTRACORPOREAL PRESSURE SHOCK WAVES - An intracorporeal pressure shock wave device to provide treatment within blood vessels artificial vessels and grafts that includes a frontal pressure shock wave reflector positioned at the distal end of an intracorporeal catheter to direct shock waves toward a treatment target, such as an occlusion and clot. | 01-28-2016 |
Iulian Cioanta, Weston, FL US
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20090281464 | Medical treatment system including an ancillary medical treatment apparatus with an associated data storage medium - A medical treatment system includes an electronic controller with a medical treatment apparatus, a data reader, an ancillary treatment apparatus used with the electronic medical treatment apparatus and a data storage medium associated with the ancillary treatment apparatus. The controller is configured to receive information from the data storage medium, and to control the medical treatment apparatus with medical treatment parameters compatible with the desired medical treatment and the ancillary treatment apparatus. | 11-12-2009 |
20100331741 | Medical treatment system including an ancillary medical treatment apparatus with an associated data storage medium - A medical treatment system includes an electronic controller with a medical treatment apparatus, a data reader, an ancillary treatment apparatus used with the electronic medical treatment apparatus and a data storage medium associated with the ancillary treatment apparatus. The controller is configured to receive information from the data storage medium, and to control the medical treatment apparatus with medical treatment parameters compatible with the desired medical treatment and the ancillary treatment apparatus. | 12-30-2010 |
20110034832 | Usage of Extracorporeal and Intracorporeal Pressure Shock Waves in Medicine - A shock wave applicator includes a shock wave generator and an asymmetrical reflector portion in a housing. Asymmetry of the reflector portion is combined with one or more wave generators to produce a variety of focal volumes and wave fronts for medical treatment. | 02-10-2011 |
Iulian Cioanta, Alpharetta RO
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20130164419 | Methods and Devices for Cleaning and Sterilization with Shock Waves - Shock waves are applied to clean and sterilize fluids in containers and conveyances. Shock waves destroy pathogens and pollutants in blood, water, food liquids and other fluids. | 06-27-2013 |
Iulian Cioanta, Duluth, GA US
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20110064611 | Methods and Devices for Cleaning and Sterilization with Shock Waves - Shock waves are applied to clean and sterilize fluids in containers and conveyances. Shock waves destroy pathogens and pollutants in blood, water, food liquids and other fluids. | 03-17-2011 |
20110087157 | Use of Pressure Waves for Stimulation, Proliferation, Differentiation and Post-Implantation Viability of Stem Cells - Stem cells are proliferated with the application of acoustic pressure waves, including cambium cells of periosteum treated in-vivo with acoustic pressure waves. Following harvesting and viability assessment of in-vivo or in-vitro proliferated stem cells, acoustic pressure waves are applied to enhance in-vivo or in-vitro differentiation either before or after implantation of the stems cells to an organism. Acoustic pressure waves also stimulate an implantation site to enhance viability and to grow desired tissue. | 04-14-2011 |
Iulian Ciotlos, Troy, MI US
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20160121884 | IMPACT MITIGATION BY INTELLIGENT VEHICLE POSITIONING - A method and system for mitigating the impact of a vehicle collision senses location, speed, orientation, and direction of movement data of a host vehicle and an interfering vehicle that has moved or is moving into the path of the host vehicle. A control unit analyzes the data and determines whether a collision is unavoidable. If so, the control unit determines a vehicle path for the host vehicle that will minimize the effects of the collision. By changing the vehicle path, the impact of the collision is less direct and the effect on both of the vehicles is mitigated to some degree. | 05-05-2016 |
Iulian Dumitru, Bucuresti RO
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20100045343 | Current Limited Voltage Supply - A current limited voltage supply including a transistor and a capacitor is provided for powering digital logic cells of an integrated circuit. The transistor is connected in a current mirror configuration, such that a constant reference current is mirrored through the transistor to create a first supply current. The transistor is coupled to the digital logic cells and the capacitor. The first supply current is used to charge the capacitor while the digital logic cells are not switching. While the digital logic cells are switching, the capacitor discharges to the digital logic cells, thereby providing the digital logic cells with sufficient energy to implement high-speed switching. The capacitor minimizes voltage fluctuations within in the current limited voltage supply, such that analog circuitry can be reliably powered from a different branch of the same current mirror circuit. | 02-25-2010 |
20140254244 | Resistive Random Access Memory (RERAM) and Conductive Bridging Random Access Memory (CBRAM) Cross Coupled Fuse and Read Method and System - By arranging both a conductive and non-conductive resistive memory cell in a cross coupled arrangement to facilitate reading a data state the memory cells can have very small differences in their resistance values and still read correctly. This allows both of the memory cells' resistances to change over time and still have enough difference between their resistances to read the desired data state that was programmed. A pair of ReRAM or CBRAM resistive memory devices are configured as a one bit memory cell and used to store a single data bit wherein one of the resistive memory devices is in an ERASE condition and the other resistive memory devices of the pair is in a WRITE condition. Reading the resistance states of the resistive memory device pairs is accomplished without having to use a reference voltage or current since a trip-point is between the conductive states thereof. | 09-11-2014 |
Iulian Gherasoiu, Gilbert, AZ US
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20110005590 | Tandem Photoelectrochemical Cell for Water Dissociation - A tandem photoelectrochemical (PEC) cell including a nitride PEC semiconductor connected in series with a current matched photovoltaic (PV) Si solar cell that provides an internal biasing voltage. A low resistance tunnel junction is formed between the PEC semiconductor and PV cell. The tandem PEC cell is placed together with a counter electrode in contact with an aqueous solution, such that, when exposed to solar radiation, the PEC semiconductor utilizes high energy photons to split water while the PV cell utilizes low energy photons to bias the tandem PEC cell to eliminate the barrier between Fermi energy and redox potentials, thereby initiating the spontaneous dissociation of water in the aqueous solution into hydrogen and oxygen. The conduction band edge (CBE) for n-type PEC semiconductor is located in the vicinity of the Fermi stabilization energy to reduce the barriers for the charge transfer between the PEC semiconductor and the aqueous solution. | 01-13-2011 |
20120125417 | Photovoltaic Device With Three Dimensional Charge Separation and Collection - A photovoltaic device having three dimensional (3D) charge separation and collection, where charge separation occurs in 3D depletion regions formed between a p-type doped group III-nitride material in the photovoltaic device and intrinsic structural imperfections extending through the material. The p-type group III-nitride alloy is compositionally graded to straddle the Fermi level pinning by the intrinsic structural imperfections in the material at different locations in the group III-nitride alloy. A field close to the surfaces of the intrinsic defects separates photoexcited electron-hole pairs and drives the separated electrons to accumulate at the surfaces of the intrinsic defects. The intrinsic defects function as n-type conductors and transport the accumulated electrons to the material surface for collection. The compositional grading also creates a potential that drives the accumulated separated electrons toward an n-type group III-nitride layer for collection. The p-type group III-nitride alloy may comprise an alloy of InGaN, InAlN or InGaAlN. | 05-24-2012 |
20130026484 | Multi-Color Light Emitting Devices with Compositionally Graded Cladding Group III-Nitride Layers Grown on Substrates - A light emitting device includes a substrate, multiple n-type layers, and multiple p-type layers. The n-type layers and the p-type layers each include a group III nitride alloy. At least one of the n-type layers is a compositionally graded n-type group III nitride, and at least one of the p-type layers is a compositionally graded p-type group III nitride. A first ohmic contact for injecting current is formed on the substrate, and a second ohmic contact is formed on a surface of at least one of the p-type layers. Utilizing the disclosed structure and methods, a device capable of emitting light over a wide spectrum may be made without the use of phosphor materials. | 01-31-2013 |
Iulian Iordachita, Towson, MD US
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20130190734 | INTERFEROMETRIC FORCE SENSOR FOR SURGICAL INSTRUMENTS - A surgical tool system according to an embodiment of the current invention includes a surgical tool, and an interferometry system optically coupled to the surgical tool. The surgical tool includes a body section, a sensor section at least one of attached to or integral with the body section, and a surgical section at least one of attached to or integral with the sensor section at an opposing end of the sensor section from the body section. The sensor section comprises an interferometric optical sensor defining a reference distance that changes in response to at least one of a force or a torque when applied to the surgical section of the surgical tool. | 07-25-2013 |
20130304258 | MICRO-FORCE GUIDED COOPERATIVE CONTROL FOR SURGICAL MANIPULATION OF DELICATE TISSUE - A method and system for micro-force guided cooperative control that assists the operator in manipulating tissue in the direction of least resistance. A tool holder receives a surgical tool adapted to be held by a robot and a surgeon. A first sensor measures interaction forces between a tip of the surgical tool and tissue of a region of interest. A second sensor measures interaction forces between the surgeon and a handle to the surgical tool. A data processor is configured to perform an algorithm to actively guide the surgical tool by creating a bias towards a path of least resistance and limit directional tool forces of the surgical tool as a function of handle input forces and tip forces. This function offers assistance to challenging retinal membrane peeling procedures that require a surgeon to delicately delaminate fragile tissue that is susceptible to hemorrhage and tearing due to undesirable forces. | 11-14-2013 |
20140052150 | METHOD FOR PRESENTING FORCE SENSOR INFORMATION USING COOPERATIVE ROBOT CONTROL AND AUDIO FEEDBACK - A system and method for cooperative control of surgical tool includes a tool holder for receiving a surgical tool adapted to be held by a robot and a surgeon, a sensor for detecting a force based on operator input and/or tool tip forces, a controller for limiting robot velocity based upon the force detected so as to provide a haptic feedback, a selector for automatically selecting one level of a multi-level audio feedback based upon the detected force applied, the audio feedback representing the relative intensity of the force applied, and an audio device for providing the audio feedback together with the haptic feedback. The audio feedback provides additional information to the surgeon that allows lower forces to be applied during the operation. | 02-20-2014 |
Iulian Mirea, Singapore SG
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20090108820 | Topology for a positive buck-boost switching regulator - A new topology for a buck-boost switching regulator is provided herein. Embodiments provide an efficient buck-boost switching regulator that provides a regulated output voltage from an unregulated input voltage. Embodiments include a buck-boost switching regulator topology, where the operating mode is determined separately from the pulse-width modulated (PWM) control signal. This topology, in one embodiment, provides a better transient response than typical buck-boost switching regulator topologies, where PWM control circuitry and operating mode circuitry are combined. Furthermore, embodiments provide a buck-boost switching regulator that allows for high efficiency when the output voltage is close to the input voltage. | 04-30-2009 |
20110121805 | Active Power Switch Topology for Switching Regulators - Embodiments of an active power switch topology for a switching regulator are provided herein. The embodiments of the active power switch topology use two or more active power switches in parallel instead of a single active power switch, as found in conventional implementations. The active power switches are controlled such that they turn-on and -off in a manner that reduces parasitic voltage spikes associated with conventional switching regulators, while not degrading efficiency or other parameters associated with the switching regulator. The active power switch topology can be beneficially used within many switching regulators (e.g., buck, boost, or buck-boost) and, in particular, within hard-switched switching regulators that include active power switches integrated on chip. | 05-26-2011 |
Iulian Mirea, San Jose, CA US
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20130049711 | Frequency Lock Loop for Hysteretic Switching Regulators - Embodiments of the present invention provide systems and methods for reducing switching frequency variation in a hysteretic switching regulator. Embodiments of the present invention provide a new duty cycle controller for a switching regulator incorporating a new Frequency Lock Loop (FLL) for controlling the hysteresis of a comparator, and this hysteresis variation directly controls the switching frequency. The FLL of the present invention advantageously maintains a fixed frequency operation for a switching regulator while not affecting the transient response or stability of the main loop because it only changes the hysteresis of the fast comparator and does not introduce delays in the main loop of the switching regulator. Thus, the FLL of the present invention advantageously maintains a fixed switching frequency while causing a minimal impact to the switching regulator. | 02-28-2013 |
Iulian Mitea, Windsor CA
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20110278891 | MODULAR CONTOUR SUPPORT APPARATUS - A four way lumbar support for an automobile seat includes a wire array, a fixed frame, and a basculating arm. When in its extended position, the basculating arm exerts pressure on the wire array thus providing lumbar support to the seat occupant at that point. A system of cables and sliding connections allows the basculating arm to slide along the fixed frame so that the lumbar support may be provided at different heights within the seat. | 11-17-2011 |
Iulian Raducanu, Markham CA
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20150241893 | SYSTEMS AND METHODS FOR ERROR MONITORING AND HANDLING IN CONTROL SYSTEMS - In a first embodiment, a system for controlling a microgrid includes a processor-based control system. The control system is configured to receive information via a communications pathway from at least one microgrid asset within a microgrid system and identify one or more errors associated with an operation of the microgrid system. In addition, the control system is configured to respond to the one or more identified errors with one or more actions. Each identified error from the one or more identified errors is associated with at least one action from the one or more actions. Further, control system is configured to generate an optimal dispatch schedule having one or more control signals configured to control the microgrid operation to reduce cost and to improve an operational efficiency of the microgrid. The optimal dispatch schedule is based at least in part on the response to the one or more identified errors. | 08-27-2015 |
Iulian Raducanu, North York CA
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20080239602 | FAST IMPEDANCE PROTECTION TECHNIQUE IMMUNE TO DYNAMIC ERRORS OF CAPACITIVE VOLTAGE TRANSFORMERS - The present invention relates to methods for providing impedance protection differentiating between in-zone and out-of-zone faults based on instantaneous, digitally derived operating and polarizing, distance comparator signals. The method uses a pair of fast orthogonal filters to derive D and Q components of the input voltages and currents. Two sets of operating and polarizing signals are derived for better speed of response under varying fault moment with respect to the peaks and zero crossings of power signals. Three stages of comparison between the operating and polarizing impedance terms are used. These comparator stages use half a cycle averaging windows, and three-quarters-of-a-cycle windows. The first stage of comparison is based on energy comparator responding to both magnitude and phase information in the signals. Stages 2 and 3 are of phase comparison type, responding mostly at the phase information and neglecting the magnitude information for better immunity to noise and signal distortions. | 10-02-2008 |
20080243413 | SELF-ADJUSTING VOLTAGE FILTERING TECHNIQUE COMPENSATING FOR DYNAMIC ERRORS OF CAPACITIVE VOLTAGE TRANSFORMERS - A method of digitally correcting the raw output voltage from a Capacitive Voltage Transformer (CVT) with the intent to remove transient components impacting on transient accuracy of protection function. A typical CVT is represented using three parameters in the linear CVT model. A digital filter designed based on the three parameters and incorporating a dedicated mechanism to ensure numerical stability of the former. A method of self-adjusting the said filter based on system events and performed after the method has been deployed in the field and supplied from a specific CVT. | 10-02-2008 |