Patent application number | Description | Published |
20090074848 | COMBINATION FORMULATIONS OF CYTIDINE ANALOGS AND PLATINUM AGENTS - Compositions which comprise delivery vehicles having stably associated therewith a cytidine analog and a platinum agent are useful in achieving enhanced therapeutic effects when combinations of these drugs are administered. | 03-19-2009 |
20090098196 | LIPID CARRIER COMPOSITIONS WITH REDUCED POLY-DISPERSITY - The invention relates to a method for reducing the polydispersity of a population of gel-phase lipid-based delivery vehicles. | 04-16-2009 |
20090148506 | LIPOSOMAL FORMULATIONS COMPRISING SECONDARY AND TERTIARY AMINES AND METHODS FOR PREPARING THEREOF - Provided herein are liposomal compositions comprising a therapeutic agent having a protonatable amino group and a secondary or tertiary amine, and methods for encapsulating such therapeutic agents. In one aspect, the present invention relates to liposomal formulations comprising irinotecan in a triethanolamine solution, and optionally comprising copper gluconate, and methods for preparing the same. | 06-11-2009 |
20110002982 | LIPID CARRIER COMPOSITIONS WITH ENHANCED BLOOD STABILITY - Liposomes that contain at least 10 mol % of a negatively charged lipid coupled to a non-zwitterionic moiety are stable in the blood. Liposomes containing at least 1 mol % of such lipids may be frozen safely. | 01-06-2011 |
20110223241 | COMBINATION METHODS AND COMPOSITIONS - Compositions which comprise a liposomal water-soluble camptothecin and optionally a liposomal fluoropyrimidine in combination with a vascular epithelial growth factor (VEGF) inhibitor such as cetuximab or an epidermal growth factor receptor (EGFR) inhibitor such as bevacizumab are useful in achieving enhanced therapeutic effects for the treatment of cancer. | 09-15-2011 |
20120003294 | FIXED RATIO CAMPTOTHECENS/PLATINUM AGENTS - Compositions which comprise liposomes having controlled release of a platinum agent are useful in achieving enhanced therapeutic effects particularly when these drugs are administered in combination with other therapeutic agents. | 01-05-2012 |
20140255475 | METHOD OF LYOPHILIZING LIPOSOMES - Lyophilized liposomal formulations with two or more encapsulated drugs are disclosed. These formulations display superior drug retention profiles and also maintain size distribution following lyophilization and reconstitution. | 09-11-2014 |