Patent application number | Description | Published |
20080275433 | APPARATUS AND METHOD FOR GENERATING CUT SURFACES IN THE CORNEA OF AN EYE FOR CORRECTION OF AMETROPIA - An apparatus for generating cut surfaces in the cornea of an eye in order to correct ametropia is provided, said apparatus comprising a laser unit, which can focus pulsed laser radiation into the cornea and move it therein in order to generate cut surfaces, and a control unit, which controls the laser unit for generating cut surfaces such that a predetermined lenticle to be removed is separated from the surrounding corneal material in the cornea by at least one cut surface, and that at least two mutually spaced apart cut surfaces are formed as opening cuts, each extending from the lenticle to the anterior corneal surface, the position and shape of the opening cuts being selected such that the opening cuts contribute to the correction of the ametropia of the eye or do not counteract the correction of the ametropia of the eye. | 11-06-2008 |
20090304591 | METHOD AND DEVICE FOR OPTICAL DETECTION OF THE EYE - A solution for optical detection of the eye. Molecular markers are used for high-contrast diagnosis of eye diseases, other diseases, and other vital parameters which can be diagnosed in the eye. For optical detection of the eye, a molecular marker with spectral characteristics of absorption and/or scattering in the visual and infrared spectral region is introduced into the eye and bound to a specific target. The interaction of the molecular marker with the target is detected by means of optical imaging methods, such as fundus photography, confocal laser microscopy, polarisation-optical imaging methods, holographic methods or especially OCT methods. The use of optical methods is strongly preferred for the diagnosis of the eye as a result of the high transparency of the optical system of the eye compared to other body parts. | 12-10-2009 |
20120229766 | METHOD AND DEVICE FOR DETECTING DEPOSITS IN THE EYE - A method and devices for detecting deposits, in particular amyloid plaques, in the eye, in particular in the human eye. The subject is an optical method for detecting deposits, in particular β-amyloid, in the retina, which is locally resolved and wherein the local resolution is better than the layer thickness of individual layers of the retina. The invention includes a device for optically detecting β-amyloid in the retina, which generates a locally resolved image of the retina and wherein the local resolution is better than the layer thickness of individual layers of the retina. | 09-13-2012 |
20130116757 | METHOD AND DEVICE FOR STABILIZING THE CORNEA - A method and device to stabilize the cornea with fewer adverse effects. In particular, a greater stability and shorter treatment time are to be made possible. To this end, the cornea is locally irradiated successively at different sites so that collagen fibers are indirectly or directly crosslinked at the irradiated sites. In this way, the collagen fibers are advantageously crosslinked in a spatially resolved manner. Accordingly, the entire eye need not be irradiated with tissue-damaging UV light, and regions having a weaker structure can be locally stabilized selectively. The sites of the cornea are preferably irradiated so that the collagen fibers are ionized in each instance by photoabsorption of a plurality of photons which each have an energy below an ionizing energy of a given molecule. After a short treatment period, strong covalent bonds are formed directly between the collagen fibers. Crosslinking agents need not be used. | 05-09-2013 |
20140288538 | TREATMENT DEVICE FOR THE SURGICAL CORRECTION OF DEFECTIVE VISION OF AN EYE, METHOD FOR PRODUCING CONTROL DATA THEREFOR, AND METHOD FOR THE SURGICAL CORRECTION OF DEFECTIVE VISION OF AN EYE - A treatment device for the surgical correction of defective vision in an eye. The device includes a laser apparatus controlled by a controller. The controller determines a desired correction of defective vision from measurement data of the eye to produce control data for the laser, and to control the laser to emit radiation according to the control data, such that a lenticule-shaped volume is isolated in the cornea. The controller computes a lenticule-shaped intended volume, the removal of which from the cornea leads to an actual correction of defective vision in an optical zone in the eye which differs from the desired correction more at the edge of the optical zone than at the center of the optical zone. The thickness of the lenticule-shaped intended volume is less than the thickness of a lenticule-shaped comparison volume, the removal of which would bring about the desired correction of defective vision. | 09-25-2014 |
Patent application number | Description | Published |
20110311982 | Nucleic Acid Isolation Using Polidocanol and Derivatives - This invention relates to a composition comprising a chaotropic agent, a buffering substance, and 0.5 to 5% (V/V) polidocanol or a derivative thereof. The invention is further related to uses of this composition and to a kit comprising the composition according to the invention. The invention is further related to a method for the detection of a nucleic acid in a biological sample comprising the steps of incubating the biological sample in the presence of a chaotropic agent, a buffering substance, and 0.5 to 5% (V/V) polidocanol or a derivative thereof, optionally isolating the nucleic acid, optionally amplifying the nucleic acid, and detecting the nucleic acid. The invention is further related to a method for the purification of a nucleic acid in a biological sample comprising the steps of incubating the biological sample in the presence of a chaotropic agent, a buffering substance, and 0.5 to 5% (V/V) polidocanol or a derivative thereof and isolating the nucleic acid thereby purifying the nucleic acid. | 12-22-2011 |
20120100599 | Nucleic Acid Isolation Using Polidocanol and Derivatives - This invention relates to a composition comprising a chaotropic agent, a buffering substance, and 0.5 to 5% (V/V) polidocanol or a derivative thereof. The invention is further related to uses of this composition and to a kit comprising the composition according to the invention. The invention is further related to a method for the detection of a nucleic acid in a biological sample comprising the steps of incubating the biological sample in the presence of a chaotropic agent, a buffering substance, and 0.5 to 5% (V/V) polidocanol or a derivative thereof, optionally isolating the nucleic acid, optionally amplifying the nucleic acid, and detecting the nucleic acid. The invention is further related to a method for the purification of a nucleic acid in a biological sample comprising the steps of incubating the biological sample in the presence of a chaotropic agent, a buffering substance, and 0.5 to 5% (V/V) polidocanol or a derivative thereof and isolating the nucleic acid thereby purifying the nucleic acid. | 04-26-2012 |
20130280697 | HEV Assay - A method of simultaneously amplifying genotypes 1, 2, 3 and/or 4 of HEV is disclosed comprising amplifying the genotypes 1, 2, 3 and/or 4 of HEV with one single none-degenerate forward primer partially overlapping the 5′UTR region of HEV and at least one reverse primer. Also disclosed are related methods comprising a probe, and kits for the detection of genotypes 1, 2, 3 and/or 4 of HEV. | 10-24-2013 |