David Hugh
David Hugh Armet, Williamstown, MA US
Patent application number | Description | Published |
---|---|---|
20150202491 | Multi-Directional Adjustable Exercise Slide Board - An adjustable exercise slide board, includes a base having a top surface and a bottom surface, wherein the top surface is smooth and planar; wherein the top surface includes a plurality of apertures, wherein each aperture is in a keyhole configuration having a larger diameter portion and a smaller diameter portion; and a plurality of repositional stops including mounting posts configured to be selectively received within a selected plurality of the apertures in the top surface for selectively securing the repositional stops to the top surface, wherein the mounting posts include a large distal head and smaller shaft wherein the large distal head is sized and configured to fit into the larger diameter of the keyhole shaped aperture and the smaller shaft of the mounting post allows the post to slide to the smaller diameter portion of the keyhole shaped aperture thereby locking the mounting post within the aperture. | 07-23-2015 |
David Hugh Giamalva, Glen Allen, VA US
Patent application number | Description | Published |
---|---|---|
20150272909 | Pharmaceutical Composition Containing Sympathomimetic Amine Salt and Co-distillable Additive - A pharmaceutical composition is provided which contains a water soluble acid salt of a sympathomimetic amine, e.g., pseudoephedrine, and an additive, e.g., a volatile amine or other odorant, that is co-distillable, e.g., by steam distillation, with the sympathomimetic amine and/or its derivatives, e.g., its free base. | 10-01-2015 |
David Hugh Jones, Mountain View, CA US
Patent application number | Description | Published |
---|---|---|
20090324639 | COMPOSITIONS AND METHODS FOR ACTIVATING INNATE AND ALLERGIC IMMUNITY - Methods for making and using therapeutic formulations of Proteosome-based immunoactive compositions are provided. The immunogenic compositions, which include Proteosomes and liposaccharides, may be used to elicit or enhance a nonspecific innate immune response to, for example, treat or prevent infectious disease. In addition, after activating the innate immune system, immunogenic compositions further containing an antigen may be used to elicit a specific adaptive immune response. Furthermore, provided are compositions capable of altering hyperreactive responses or inflammatory immune responses, such as allergic reactions. Such compositions may be used as a prophylactic, or in various clinical settings to treat or prevent infectious disease (such as parasite, fungal, bacterial or viral infections), or to alter inappropriate inflammatory immune responses (such as allergic reactions or asthma). | 12-31-2009 |
20120276140 | COMPOSITIONS AND METHODS FOR ACTIVATING INNATE AND ALLERGIC IMMUNITY - Methods for making and using therapeutic formulations of Proteosome-based immunoactive compositions are provided. The immunogenic compositions, which include Proteosomes and liposaccharides, may be used to elicit or enhance a nonspecific innate immune response to, for example, treat or prevent infectious disease. In addition, after activating the innate immune system, immunogenic compositions further containing an antigen may be used to elicit a specific adaptive immune response. Furthermore, provided are compositions capable of altering hyperreactive responses or inflammatory immune responses, such as allergic reactions. Such compositions may be used as a prophylactic, or in various clinical settings to treat or prevent infectious disease (such as parasite, fungal, bacterial or viral infections), or to alter inappropriate inflammatory immune responses (such as allergic reactions or asthma). | 11-01-2012 |
20140234374 | COMPOSITIONS AND METHODS FOR ACTIVATING INNATE AND ALLERGIC IMMUNITY - Methods for making and using therapeutic formulations of Proteosome-based immunoactive compositions are provided. The immunogenic compositions, which include Proteosomes and liposaccharides, may be used to elicit or enhance a nonspecific innate immune response to, for example, treat or prevent infectious disease. In addition, after activating the innate immune system, immunogenic compositions further containing an antigen may be used to elicit a specific adaptive immune response. Furthermore, provided are compositions capable of altering hyperreactive responses or inflammatory immune responses, such as allergic reactions. Such compositions may be used as a prophylactic, or in various clinical settings to treat or prevent infectious disease (such as parasite, fungal, bacterial or viral infections), or to alter inappropriate inflammatory immune responses (such as allergic reactions or asthma). | 08-21-2014 |
David Hugh Jones US
Patent application number | Description | Published |
---|---|---|
20080260781 | PROTEOSOME INFLUENZA VACCINE - Improved forms of vaccines which comprise proteosomes and protein antigens are described. Vaccines which contain influenza HA as the antigen are used for illustration as to demonstrate efficacy. Improvements in the preparation of the vaccines themselves and the proteosome component are also included. | 10-23-2008 |
David Hugh Williams, Liverpool, Merseyside GB
Patent application number | Description | Published |
---|---|---|
20150362431 | MODULAR ASSAY SYSTEM - A system for conducting an assay comprises a power source ( | 12-17-2015 |
David Hugh Williams, Cambridgeshire GB
Patent application number | Description | Published |
---|---|---|
20100331328 | BICYCLYLARYL-ARYL-AMINE COMPOUNDS AND THEIR USE - The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain bicyclylaryl-aryl-amines compounds of the following formula (referred to herein as BCAA compounds), which, inter alia, inhibit Checkpoint Kinase 1 (CHK1) kinase function. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit CHK1 kinase function, and in the treatment of diseases and conditions that are mediated by CHK1, that are ameliorated by the inhibition of CHK1 kinase function, etc., including proliferative conditions such as cancer, etc., optionally in combination with another agent, for example, (a) a DNA topoisomerase I or II inhibitor; (b) a DNA damaging agent; (c) an antimetabolite or TS inhibitor; (d) a microtubule targeted agent; and (e) ionising radiation: | 12-30-2010 |
20150307873 | BACTERIAL ENGINEERING - Described is a process for producing a mutant bacterium which exhibits improved survival and/or growth under a selected growth condition, the process comprising the steps of: (a) generating a pool of mutant bacteria by transposon mutagenesis with an activating transposon (TnA), wherein the TnA comprises a promoter capable of increasing transcription of a gene at or near its insertion site; (b) growing bacteria from the mutant pool under the selected growth condition and under one or more reference conditions to produce two or more test cultures; and (c) comparing the distribution of TnA insertions between test cultures to identify a first class of genes which are disadvantageous for growth and/or survival under the selected growth condition and a second class of genes which are advantageous for growth and/or survival under the selected growth condition. | 10-29-2015 |
David Hugh Williams, Guildford GB
Patent application number | Description | Published |
---|---|---|
20160105784 | TECHNIQUES FOR SUPPORTING TELEMATICS-ENHANCED EMERGENCY CALLS FROM MOBILE PHONES - Methods, systems, apparatuses, and computer-readable mediums are described for techniques for supporting telematics-enhanced emergency calls from mobile phones. In some aspects, a method for wireless communication may include establishing, by a user equipment (UE), a personal telematics-enhanced emergency call to a public safety answering point (PSAP), wherein the UE is capable of transmitting telematics data. The method may also include transmitting information that distinguishes the personal telematics-enhanced emergency call from other types of emergency calls. | 04-14-2016 |
David Hugh Williams, Melbourn GB
Patent application number | Description | Published |
---|---|---|
20120040967 | Pyrazin-2-yl-pyridin-2-yl-amine and pyrazin-2-yl-pyrimidin-4-yl-amine Compounds and Their Use - The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain biarylamine compounds (referred to herein as BAA compounds), and especially certain pyrazin-2-yl-pyridin-2-yl-amine and pyrazine-2-yl-pyrimidin-4-yl-amine compounds, which, inter alia, inhibit Checkpoint Kinase 1 (CHK1) kinase function. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit CHK1 kinase function, and in the treatment of diseases and conditions that are mediated by CHK1, that are ameliorated by the inhibition of CHK1 kinase function, etc., including proliferative conditions such as cancer, etc., optionally in combination with another agent, for example, (a) a DNA topoisomerase I or II inhibitor; (b) a DNA damaging agent; (c) an antimetabolite or TS inhibitor; (d) a microtubule targeted agent; and (e) ionising radiation. | 02-16-2012 |
David Hugh Williams, Malaga ES
Patent application number | Description | Published |
---|---|---|
20120289179 | HOME NETWORK ROAMING MANAGEMENT FOR eCALL-ONLY SUBSCRIBERS - A Home Public Land Mobile Network (HPLMN) or home network immediately accepts a registration requests from “eCall-only” subscribers attempting to register with any Visitor Public Land Mobile Networks (VPLMNs) or roaming network. This avoids unnecessary delays in the establishment of an eCall (emergency call) that might be otherwise introduced by the home network's roaming registration management policy (RRMP) that otherwise would only permit registrations (and subsequent call servicing) by preferred roaming VPLMN partners and automatically reject registrations from non-preferred roaming networks (which may hinder or prevent timely completion of an eCall). | 11-15-2012 |
20130194919 | APPARATUS AND METHOD FOR USER EQUIPMENT ASSISTED CONGESTION CONTROL - A method, an apparatus, and a computer program product for wireless communication are provided in connection with improving QoE in RAN congestion. In one example, a communications device is equipped to indicate a quality control indicator (QCI) for each of a plurality of applications that communicate with a RAN over a bearer, receive information regarding modification of the bearer or additional bearers based on the QCIs, and modify the bearer or additional bearers according to the information to achieve a desired QoE for at least one of the plurality of applications. In another example, a RAN is equipped to receive a QCI for each of a plurality of applications related to a bearer from a UE, and modify the bearer or adding additional bearers for communicating with the UE based on the QCI for each of the plurality of applications to improve QoE at the UE. | 08-01-2013 |
David Hugh Williams, Malaga GB
Patent application number | Description | Published |
---|---|---|
20140094210 | CONTROLLING THE TRANSFER OF TELEMATICS DATA USING SESSION RELATED SIGNALING - Methods, systems, and devices are described for communicating telematics data and metadata. A first device transmits a first signaling message to a second device over a communication session signaling protocol. The first signaling message includes at least a first set of session information related to a communication session between the first device and the second device and a first set of telematics data for the first device. The first device receives a second signaling message from the second device over the communication session signaling protocol. The second signaling message includes metadata based on a content of the first set of telematics data transmitted in the first signaling message. | 04-03-2014 |