Marechal
Daniel Marechal, Louveigne BE
Patent application number | Description | Published |
---|---|---|
20100322850 | NEW PLASMA MEMBRANE BIOMARKERS PREFERENTIALLY EXPRESSED IN PANCREATIC BETA CELLS USEFUL IN IMAGING OR TARGETING BETA CELLS - The present invention is directed to the identification of a biomarker specifically located in the plasma membrane of pancreatic beta cells. It was selected by a Systems Biology approach on Massively Parallel Signal Sequencing datasets obtained in human islets and Affymetrix microarray datasets on human islets, purified rat primary beta and non beta cells and insulinoma cells. Based on a set of specific features the biomarker is a unique candidate for imaging and targeting strategies to study the pancreatic beta cell mass in health and disease (T1 D, T2D, pancreatic cancers, obesity, islet transplantation, beta cell regeneration). The five specific features of the selected biomarkers are: 1) Preferentially expressed in pancreatic islets as compared to surrounding tissues; 2) Higher expression in pancreatic beta cells than in pancreatic alpha cells or than in other islet non-beta cells; 3) Expression levels in pancreatic beta cells are higher or comparable to glucokinase which is an enzyme specifically expressed in the pancreatic beta cell; 4) Located in the membrane and as such targetable with antibodies, peptides or small molecules which allows imaging, targeting and immunohistochemistry; and 5) Expression is not induced during the process of inflammation of the beta cell mass and the protein is not enriched in T-cells and dendritic cells or in other cells participating in the inflammation process. | 12-23-2010 |
Dominique Marechal, Laval CA
Patent application number | Description | Published |
---|---|---|
20100203134 | SPHEROIDS AND MULTIPARTICULATE TABLETS COMPRISING THEM - The invention relates to a directly-compressible gastro-resistant spheroid. The spheroid comprises: (i) a core containing one or more active substances; (ii) a flexible, deformable film which directly coats the aforementioned core and which comprises an enteric polymer and a mixture of saturated and/or unsaturated polyglycosylated glycerides, the fatty acids of which include at least 8 carbon atoms; and (iii) an outer water-dispersible layer containing at least one disintegrating agent. The invention further relates to multiparticular tablets comprising said spheroids. | 08-12-2010 |
20110081389 | COMPOSITION COMPRISING A MIXTURE OF ACTIVE PRINCIPLES, AND METHOD OF PREPARATION - Active principle-based coated particle, in which both the core and the coating contain active principle, includes a core which contains a first active principle while the coating contains a second active principle, which is different in nature. | 04-07-2011 |
Francis Marechal, Orbe CH
Patent application number | Description | Published |
---|---|---|
20120117979 | HYBRID CYCLE SOFC - INVERTED GAS TURBINE WITH CO2 SEPARATION - A new gas turbine-fuel cell Hybrid Cycle is proposed. The fuel cell advantageously operates close or under atmospheric pressure and is fully integrated with the gas turbine that is based on an Inverted Brayton-Joule Cycle. The idea of the invention is to capitalize on the intrinsic oxygen-nitrogen separation characteristic of the fuel cell electrolyte by sending to the Inverted Brayton-Joule Cycle only the anodic flow, which is the one free of nitrogen. In this way the flow that expands in the turbine consists only in steam and carbon dioxide. After the expansion the steam can be easily condensed, separated and pumped up. Therefore the compressor has mainly only to compress the separated carbon dioxide. This effect generates a substantial advantage in term of efficiency and enables separating the carbon dioxide. The new proposed Hybrid Cycle enables to: substantially increase the system efficiency compared to the known gas turbine-fuel cell Hybrid Cycle, maintain the fuel cell operating under or close to atmospheric pressure and separate the carbon dioxide. | 05-17-2012 |
Frederic Marechal, Athus BE
Patent application number | Description | Published |
---|---|---|
20130075041 | SOLID DECK BEAD LOCK DRUM - A rotatable tire building drum | 03-28-2013 |
Frederic Marie Bernard Marechal, Selange BE
Patent application number | Description | Published |
---|---|---|
20140027063 | TIRE BUILDING MACHINE WITH EXTENDABLE DRUMS - A tire building machine includes a support housing for rotating the machine about a vertical axis, a support frame operatively attached to the support housing such that the support housing rotates the support frame about the vertical axis, a first drum rotatable about a first horizontal axis by a first motor, the first drum and the first motor being secured to the support frame, a first cylinder for horizontally retracting the first drum along the first horizontal axis from an extended position to a retracted position, a second drum rotatable about a second horizontal axis by a second motor, the second horizontal axis being parallel to the first horizontal axis, the second drum and the second motor being secured to the support frame, and a second cylinder for horizontally retracting the second drum along the second horizontal axis from an extended position to a retracted position. | 01-30-2014 |
20150041067 | COMPONENT APPLYING/CUTTING APPARATUS FOR A TIRE BUILDING MACHINE - An apparatus cuts and applies a component to a tire during a tire building process. The apparatus includes an application head rotatable about a vertical axis and fitted to an X-Y table such that the component is applied to a curved tire profile spinning on a drum of a tire building machine. The application head feeds the component vertically downward to a predetermined position coincident with an intersection of the vertical axis of the application head and a horizontal plane defined by a horizontal axis of rotation of the drum of the tire building machine. | 02-12-2015 |
Gabriel Marechal, Carignan CA
Patent application number | Description | Published |
---|---|---|
20100234184 | METHOD AND APPARATUS FOR CONTROLLING PHYSICAL EXERTION - The present relates to a method and an apparatus for controlling physical exertion during exercise. For doing so, the method and apparatus collect at least one physical parameter of a user over time during an exercise session. The method and apparatus store the collected at least one physical parameter over time. During another exercise session, the method and apparatus measure the at least one physical parameter of the user, compare the measured at least one physical parameter with the collected at least one physical parameter with respect to time to obtain a variance, and determine a required adjustment in the another exercise session based on the variance. | 09-16-2010 |
Nadine Genevieve Marechal, South Australia AU
Patent application number | Description | Published |
---|---|---|
20090141236 | Coatings for Ophthalmic Lens Elements - The present disclosure provides a method of forming a removable protective coating on a hydrophobic surface of an ophthalmic lens element. The method includes providing an ophthalmic lens element having a hydrophobic surface. A non-aqueous coating composition is applied so as to coat at least part of the hydrophobic surface. The composition includes a film forming coating polymer and a compatible non-aqueous solvent. A substantial portion of the solvent is removed from the composition to form a removable protective coating on the ophthalmic lens element that adheres to the hydrophobic surface. The disclosure also provides a removable protective coating, and an ophthalmic lens element having the coating. | 06-04-2009 |
Nicholas J. Marechal, Tarzana, CA US
Patent application number | Description | Published |
---|---|---|
20090238470 | Adaptive membrane shape deformation system - A system and method determines the shape of a surface that preferably is a deployed space-based adaptive flexible membrane antenna, using patterned projections, image capturing, and membrane shape processing for producing membrane shape data describing the contour of the surface of the membrane with the membrane shape data then preferably used as inputs for a feedback control actuation system for deforming the membrane to a desired shaped so as to maintain the three-dimensional shape of the membrane in the desired shape. | 09-24-2009 |
Nicolas Marechal, Marcq BE
Patent application number | Description | Published |
---|---|---|
20110004788 | HANDLING AND PROCESSING OF MASSIVE NUMBERS OF PROCESSING INSTRUCTIONS IN REAL TIME - A system is designed for processing instructions in real time during a session. This system comprises: a preloader for obtaining reference data relating to the instructions, the reference data indicating the current values of each specified resource account data file, and the preloader being arranged to read the reference data for a plurality of received instructions in parallel from a master database; an enriched instruction queue for queuing the instructions together with their respective preloaded reference data; an execution engine for determining sequentially whether each received instruction can be executed under the present values of the relevant resource account files and for each executable instruction to generate an updating command; and an updater, responsive to the updating command from the execution engine (for updating the master database with the results of each executable instruction, the operation of the plurality of updaters being decoupled from the operation of the execution engine. | 01-06-2011 |
20140149342 | HANDLING AND PROCESSING OF MASSIVE NUMBERS OF PROCESSING INSTRUCTIONS IN REAL TIME - A system is designed for processing instructions in real time during a session. This system comprises: a preloader for obtaining reference data relating to the instructions, the reference data indicating the current values of each specified resource account data file, and the preloader being arranged to read the reference data for a plurality of received instructions in parallel from a master database; an enriched instruction queue for queuing the instructions together with their respective preloaded reference data; an execution engine for determining sequentially whether each received instruction can be executed under the present values of the relevant resource account files and for each executable instruction to generate an updating command; and an updater, responsive to the updating command from the execution engine (for updating the master database with the results of each executable instruction, the operation of the plurality of updaters being decoupled from the operation of the execution engine. | 05-29-2014 |
Philip E. Marechal, Mountain View, CA US
Patent application number | Description | Published |
---|---|---|
20100171808 | System and Method for Enhancing Eye Gaze in a Telepresence System - A system for enhancing eye gaze in a telepresence system includes a plurality of local cameras coupled to at least one local display. Each local camera is directed to at least one respective local user section and operable to generate an image of the respective local user section. The system also includes a plurality of remote displays. Each remote display is operable to reproduce the local video image of the local user section. Within the system the plurality of remote displays and the plurality of local cameras are aligned such that when a first local user within a local user section looks at a target at least one remote display is operable to reproduce the local video image of the first user section comprising the first local user such that the eye gaze of the reproduced image of the first local user is directed approximately at a corresponding target. | 07-08-2010 |
20100214391 | System and Method for Providing Location Specific Sound in a Telepresence System - A system for providing location-specific sound in a telepresence system includes a plurality of remote microphones. Each remote microphone is associated with a respective area and operable to generate a sound signal from the voice of at least one user within the respective area. The system also includes a plurality of remote cameras. Each remote camera is associated with a respective remote microphone of the plurality of remote microphones and aligned to generate an image of its associated respective area. The system further includes a plurality of local displays. Each local display is operable to reproduce the image of a respective area generated by a respective remote camera. The system also includes a plurality of local loudspeakers. Each local loudspeaker is positioned proximate to a respective local display and operable to reproduce the sound signal from the voice of the at least one user within the respective area reproduced by the respective local display. | 08-26-2010 |
Philippe Marechal, Nivelles BE
Patent application number | Description | Published |
---|---|---|
20090136699 | Glossy Tubes and Pipes - Tubes and pipes and methods of forming the same are described herein. The tubes and pipes include a wall structure having an external surface and an internal surface defining an internal chamber, said wall structure including at least one layer including a metallocene produced polyethylene resin and having an external surface having a gloss of at least 40 as determined by the standard test of ASTM D2457-90. | 05-28-2009 |
20090143546 | Double Loop Technology - A method for controlling the injection of catalyst slurry in a polymerization reactor is described herein. The method includes the preparation of polyethylene with a solid catalyst and a hydrocarbon diluents. The method includes providing solid catalyst and a hydrocarbon diluent in one or more storage vessels such that a catalyst slurry is obtained in said vessel, transferring said catalyst slurry from said storage vessel to a mixing vessel wherein said catalyst slurry is diluted for obtaining a suitable concentration for use in a polymerization reaction, pumping said diluted catalyst slurry at a controlled flow rate from said mixing vessel to said polymerization reactor through one or more conduits, by means of a membrane pump provided in each of said conduits, and the membrane pump is controllable as a function of reactant concentration within the polymerization reactor. | 06-04-2009 |
20130345374 | Double Loop Technology - A method for the copolymerization of ethylene and a C | 12-26-2013 |
20140299208 | Double Loop Technology - The present invention relates to an apparatus and process for polymerizing olefins. One embodiment comprises polymerizing at least one monomer in a first loop reactor in the presence of a catalyst to produce a first polyolefin fraction. A portion of the first polyolefin fraction is transferred to a second loop reactor, connected in series with the first loop reactor. The process further comprises polymerizing in the second loop reactor at least one monomer in the presence of a catalyst to produce a second polyolefin fraction in addition to the first polyolefin fraction. The combination of the first and second polyolefin fractions can produce a polymer resin fluff having bimodal molecular weight distribution. | 10-09-2014 |
Philippe Marechal, Grez-Doiceau BE
Patent application number | Description | Published |
---|---|---|
20080255323 | Low Gel Chromium Catalysis - The present invention discloses the use of a chromium-based catalyst system in two serially connected loop reactors for copolymerising ethylene and a comonomer, at reduced productivity, the final polyethylene having a reduced amount of gel. | 10-16-2008 |
Pierre Marechal, Rheinfelden CH
Patent application number | Description | Published |
---|---|---|
20100068547 | Free-Machining Powder Metallurgy Steel Articles and Method of Making Same - A small diameter, elongated steel article, comprising fully consolidated, prealloyed metal powder is disclosed. The consolidated metal powder has a microstructure that has a substantially uniform distribution of fine grains having a grain size of not larger than about 9 when determined in accordance with ASTM Standard Specification E 112. The microstructure of the consolidated metal powder is further characterized by having a plurality of substantially spheroidal carbides uniformly distributed throughout the consolidated metal powder that are not greater than about 6 microns in major dimension and a plurality of sulfides uniformly distributed throughout the consolidated metal powder wherein the sulfides are not greater than about 2 microns in major dimension. A process for making the elongated steel article is also disclosed. | 03-18-2010 |
20120321500 | Free-Machining Powder Metallurgy Steel Articles and Method of Making Same - A small diameter, elongated steel article, comprising fully consolidated, prealloyed metal powder is disclosed. The consolidated metal powder has a microstructure that has a substantially uniform distribution of fine grains having a grain size of not larger than about 9 when determined in accordance with ASTM Standard Specification E 112. The microstructure of the consolidated metal powder is further characterized by having a plurality of substantially spheroidal carbides uniformly distributed throughout the consolidated metal powder that are not greater than about 6 microns in major dimension and a plurality of sulfides uniformly distributed throughout the consolidated metal powder wherein the sulfides are not greater than about 2 microns in major dimension. A process for making the elongated steel article is also disclosed. | 12-20-2012 |
Sylvain Marechal, Bois-D'Amont CH
Patent application number | Description | Published |
---|---|---|
20140146646 | WATCH MOVEMENT COMPRISING A FUSEE - The watch movement comprises a motor barrel ( | 05-29-2014 |