Johansen, DK
Annette Helle Johansen, Broenshoej DK
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20130000055 | CLEANING COMPOSITIONS COMPRISING AMYLASE VARIANTS REFERENCE TO A SEQUENCE LISTING - The present invention relates to cleaning compositions comprising variants of an alpha-amylase and methods of treating surfaces such as textiles with aqueous liquor comprising such compositions, especially at low temperatures. | 01-03-2013 |
20130260410 | MICROPLATE SAMPLING ADAPTER - The present invention relates to adapters for microplates. The adapters allow sampling from a liquid growth medium in a microplate well after a microorganism has formed a dense layer of biomass on the surface of the growth medium. The adapters also allow easy transfer of a surface-grown microorganism from all wells of a microplate in one go, when inserted before the microorganism form the layer and then removed after incubation and layer-formation, which also enables easy sampling of the growth medium in the | 10-03-2013 |
20140141489 | ALPHA-AMYLASE VARIANTS - The present invention relates to variants of a parent alpha-amylase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants. | 05-22-2014 |
Annette Helle Johansen, Copenhagen Oe DK
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20110195481 | Variants And Compositions Comprising Variants With High Stability In Presence Of A Chelating Agent - The present invention relates to variants of an alpha-amylase having improved stability to chelating agents relative to its parent enzyme, compositions comprising the variants, nucleic acids encoding the variants, methods of producing the variants, and methods for using the variants. | 08-11-2011 |
Annette Helle Johansen, Copenhagen DK
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20100021586 | LOW POST-ACIDIFYING LACTIC ACID BACTERIA - The present invention relates to lactic acid bacteria that have low or reduced post-acidification properties, and to a method for providing such bacteria. Also, the invention relates to the use of such bacteria for manufacturing of fermented dairy products, and to dairy products containing the bacteria. | 01-28-2010 |
20110206805 | METHOD FOR MAKING CHEESE - The present invention relates to a method for making Cheddar type and Continental type cheese with an adjunct culture comprising a | 08-25-2011 |
20110212876 | CLEANING COMPOSITION COMPRISING AMYLASE VARIANTS WITH HIGH STABILITY IN THE PRESENCE OF A CHELATING AGENT - The present invention relates to cleaning compositions comprising variants of an alpha-amylase having improved stability to chelating agents relative to its parent enzyme and cleaning processes comprising such compositions. | 09-01-2011 |
Arne Johansen, Roskilde DK
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20090081042 | METHOD OF CONTROLLING A WINDMILL, ESPECIALLY IN STAND-ALONE OPERATION AND A WINDMILL - A windmill comprising a rotor having a substantially horizontal axis of rotation ( | 03-26-2009 |
Benny Johansen, Herlev DK
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20100057600 | FINANCIAL TRADING SYSTEM - Disclosed is a computer-implemented system for facilitating generation of a computer-executable financial trading strategy, the system being adapted to provide a graphical user interface for defining a financial trading strategy by arranging interconnectable building blocks into a diagram on a drawing pane provided by the graphical user interface, each building block representing a functional system component of the financial trading strategy; wherein the system includes a plurality of types of functional system components, wherein the drawing pane includes a corresponding plurality of sub-panes, and wherein the system is configured to provide functionality for a user-controlled placement of building blocks into the sub-panes corresponding to the respective types of building blocks. | 03-04-2010 |
Brian Johansen, Ejby DK
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20110241352 | FILTERING OF DEBRIS IN WIND TURBINES - A wind turbine is disclosed, the wind turbine comprising a nacelle including at least one of a debris-generating device, an inlet for air or an outlet for air. Following this invention, the wind turbine further comprises at least one electro-static filter arranged to filter at least one of the debris coming from the debris-generating device, the air coming into the nacelle through the inlet or the air coming out of the nacelle through the outlet. | 10-06-2011 |
20110248499 | WIND TURBINE COMPRISING INSULATION MONITORING SYSTEM - The present invention concerns a wind turbine comprising a generator, a controller and a measurement equipment connected to the generator, the measurement equipment being adapted to measuring at least one quality parameter indicating the quality of generator insulation of the generator, and the measurement equipment being adapted to transmitting the at least one quality parameter to the controller, wherein the controller is adapted to evaluate the at least one quality parameter according to a quality criterion and set up an alarm signal in accordance with the evaluation. Further, the invention relates to a method for upgrading a wind turbine. | 10-13-2011 |
Brian Johansen, Copenhagen K DK
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20150124978 | HUMAN LIKE EAR SIMULATOR - The present invention relates to an ear simulator representing an average acoustic ear drum impedance of ears of a population of humans. Another aspect of the invention relates to an ear simulator assembly comprising an ear simulator representing average acoustic ear drum impedance and a detachable ear canal simulator to provide an ear simulator assembly representing an acoustic impedance of a human ear canal or average human canals of the population. | 05-07-2015 |
Claus Johansen, Soenderborg DK
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20100158735 | HYDRAULIC MACHINE - A hydraulic machine has a gear wheel ( | 06-24-2010 |
Claus Jesper Johansen, Soenderborg DK
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20080240966 | HYDRAULIC MACHINE - The invention concerns a hydraulic machine ( | 10-02-2008 |
Claus Lindvald Johansen, Hojbjerg DK
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20090098592 | METHOD - A method is described for releasing a soluble or membrane associated intracellular protein of interest (POI) comprising the steps of: providing a cell comprising a soluble or membrane associated intracellular POI; contacting the cell with a membrane extracting composition; and causing the POI to be released from the cell under conditions sufficient for the specific release of the POI and in a soluble form. | 04-16-2009 |
20120083426 | METHOD - A method is described for releasing a soluble or membrane associated intracellular protein of interest (POI) comprising the steps of: providing a cell comprising a soluble or membrane associated intracellular POI; contacting the cell with a membrane extracting composition; and causing the POI to be released from the cell under conditions sufficient for the specific release of the POI and in a soluble form. | 04-05-2012 |
Elvind Johansen, Alsgarde DK
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20080309193 | Electro-Mechanical Wave Device - An electro-mechanical wave device which may be used for movement of a mechanical member, e.g. by friction, a motor comprising one or more wave devices, and a method of providing the electro-mechanical wave device. The electro-mechanical wave device comprises a substrate comprising a plurality of conductors, and a plurality of actuators positioned on the substrate for generation of mechanical waves along a predetermined propagation path, each of the actuators being connected to a respective set of the conductors of the substrate for reception of an excitation signal transmitted by the set of conductors. | 12-18-2008 |
Eric Johansen, Hoersholm DK
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20130344199 | TEXTURIZING LACTIC ACID BACTERIA STRAINS - The present invention relates to mutants of lactic acid bacteria which are resistant towards the antibiotic D-cycloserine and/or functionally equivalent antibiotics and which were found to give an increased texture when grown in milk while maintaining the other growth properties of the parent strain. The present invention, furthermore, relates to compositions comprising such mutants, and to dairy products fermented with the lactic acid bacteria resistant towards D-cycloserine and/or functionally equivalent antibiotics. | 12-26-2013 |
20140120210 | LACTOBACILLUS PLANTARUM CELLS WITH IMPROVED RESISTANCE TO HIGH CONCENTRATIONS OF ETHANOL - Cycloserine resistant mutants of lactic acid bacteria characterized by having improved resistance towards ethanol. The cycloserine resistant mutants of lactic acid bacteria can e.g. be used for malolactic fermentations of wine (i.e. including sparkling wine such as Cava/champagne) having high alcohol levels. | 05-01-2014 |
20150079058 | ANTIBIOTIC SENSITIVE BACILLUS STRAINS HAVING ANTIMICROBIAL EFFECT AGAINST E. COLI AND CLOSTRIDIUM PERFRINGENS AND HAVING HIGH SPORULATION CAPACITY | 03-19-2015 |
20150086675 | USE OF LACTIC ACID BACTERIA FOR PREPARING FERMENTED FOOD PRODUCTS WITH INCREASED NATURAL SWEETNESS - The dairy industry today faces a problem of providing an alternative to adding sweeteners to fermented milk products in order to achieve the desired sweet taste without the added calories. Furthermore, it would be highly advantageous to establish a method for reducing lactose in fermented milk products to a level which is acceptable for lactose-intolerant consumers. The above problems have been solved by providing mutant | 03-26-2015 |
Esben Weldingh Johansen, Struer DK
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20100312195 | AUTO INJECTOR WITH AUTOMATIC NEEDLE RETRACTION - The present application relates to a disposable auto injector ( | 12-09-2010 |
20110224620 | AUTO INJECTOR WITH A ROTATABLE RELEASE SHAFT - A disposable auto injector ( | 09-15-2011 |
20110224621 | AUTO INJECTOR WITH CHANGING ANCHOR LOCATIONS FOR A MECHANICAL DRIVER - The present invention relates to a disposable auto injector that can be safely operated for automatic injection of a dose of medication and having a housing for accommodation of a syringe with a needle, the syringe being movably positioned in the housing between a first position in which position the needle is accommodated inside the housing and a second position in which position the needle protrudes outside the housing, a mechanical driver anchored to the housing at a first anchor location for applying a force to the syringe thereby moving the syringe from the first position to the second position, and wherein the mechanical driver is also configured for applying a force to the syringe by anchoring the mechanical driver to a different second anchor location. | 09-15-2011 |
Finn Johansen, Middelfart DK
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20120211637 | MODULAR MOULD SYSTEM FOR MANUFACTURING A SHELL PART - A modular mould system for manufacturing a shell part of an oblong composite structure having a longitudinal direction from a fibre reinforced matrix material. The modular mould system includes a number of mould sections, which are adapted to being assembled to an assembled mould part. The number of mould sections includes a first mould section having a first moulding surface with a contour that defines a surface of a first longitudinal part of the shell part and a first end section; and a second mould section having a second moulding surface with a contour that defines a surface of a second longitudinal part of the shell part and a second end section; which, when the modular mould system is assembled to the assembled mould, the second end section of the second mould section abuts the first end section of the first mould section. | 08-23-2012 |
Flemming Johansen, Kolding DK
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20120181871 | APPARATUS AND METHOD FOR PROVIDING UNINTERRUPTIBLE POWER - Systems and methods of controlling an uninterruptible power supply are provided. The uninterruptible power supply includes an input to receive input power, and an output to provide power to a load. The uninterruptible power supply also includes an inverter, a bypass switch, and a controller. The inverter is coupled with the input and with the output, and the bypass switch can provide the input power at the output in a bypass mode of operation. The controller is coupled with the inverter and the bypass switch. The controller can activate the bypass switch in a first configuration to provide the input power at the output during a first half of a cycle of an input voltage waveform, and can activate the bypass switch in a second configuration to provide the input power at the output during a second half of the cycle. With the inverter active during bypass operation, the inverter can more quickly provide output power upon the loss of bypass power, and can provide near unity power factor correction and harmonic distortion correction. | 07-19-2012 |
20140365795 | SYSTEMS AND METHODS FOR REDUCING ENERGY STORAGE REQUIREMENTS IN A DATA CENTER - A method for reducing a need for power in a backup mode of operation in a data center includes receiving a first alert from an uninterruptible power supply indicating that the uninterruptible power supply is operating in a first mode, wherein the first mode includes deriving power from a stored energy source, identifying at least one host server configured to receive power from the uninterruptible power supply in the first mode, suspending execution of at least one virtual machine on the at least one host server, receiving a second alert from the uninterruptible power supply indicating that the uninterruptible power supply is operating in a second mode, wherein the second mode includes deriving power from one of a mains power source and a generator, and resuming execution of the at least one virtual machine. | 12-11-2014 |
Helle Krogh Johansen, Horsholm DK
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20110245148 | ACETIC ACID AND A BUFFER - The present invention relates to a composition comprising: a) 0.01-20% wt/wt acetic acid and b) a physiologically tolerable buffer capable of maintaining acetic acid at a pH in the range of 2-7; and use of such a composition as an antimicrobial agent. | 10-06-2011 |
Jan Johansen, Koge DK
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20120121116 | SUSPENSION FOR A HEARING DEVICE RECEIVER, AND A METHOD OF PRODUCING A HEARING DEVICE, AND A HEARING DEVICE - A suspension for a hearing device having a receiver includes a first part, a second part, and a vibration isolator positioned between the first and the second parts, and mechanically coupled to the first and second parts, wherein the first part is configured to at least partly enclose the receiver, wherein the second part is configured to at least partly enclose a sound outlet of the hearing device, wherein the vibration isolator comprises an acoustic passage part and a damping part enclosing the acoustic passage, wherein the acoustic passage part provides an acoustic passage between the first and second parts, wherein the damping part of the vibration isolator is asymmetrical along a longitudinal, a transverse axis, or both the longitudinal axis and the transverse axis, of the vibration isolator, and wherein the vibration isolator is freely suspended between the first and second parts. | 05-17-2012 |
20140050343 | BTE HEARING AID WITH AN ELONGATED SECURING MEMBER - A BTE hearing aid includes: a hearing aid housing configured to be worn behind a pinna; a sound signal transmission member for transmission of a hearing loss compensated output signal from a first end of the sound signal transmission member to an ear canal of a user at a second end of the sound signal transmission member; a connector at the first end of the sound signal transmission member for coupling the sound signal transmission member with the housing; and an elongated securing member with a first end coupled with the hearing aid housing, and a second end, the second end of the elongated securing member being a free end; wherein the elongated securing member extends from its first end along at least a part of the hearing aid housing, and is for improved retention of the hearing aid housing in its intended position behind the pinna. | 02-20-2014 |
20140056456 | BTE HEARING AID WITH AN ELONGATED SECURING MEMBER - A BTE hearing aid includes: a hearing aid housing configured to be worn behind a pinna of a user; and an elongated securing member having a first end coupled to the hearing aid housing proximate a sound output at the hearing aid housing, and a second end, the second end being a free end, wherein the elongated securing member is configured to be in abutment with an outer surface of an auricular sulcus for improved retention of the hearing aid housing when the hearing aid housing is worn in its intended position behind the pinna of the user. | 02-27-2014 |
20150131833 | BATTERY ASSEMBLY FOR A HEARING DEVICE AND ASSOCIATED METHOD - A battery assembly for powering a hearing device includes: a main part having at least a first surface and a second surface, the main part comprising a first electrode formed as an inductive coil; a first attachment member on at least a primary part of the first surface for attaching the main part to a hearing device housing of the hearing device; a second attachment member for attaching a direct current source to the main part; and an electronic circuit having a first input terminal and a second input terminal connectable to a first output terminal and a second output terminal, respectively, of the direct current source, wherein the electronic circuit is connected to the first electrode, and wherein the electronic circuit is configured for converting direct current from the direct current source to alternating current. | 05-14-2015 |
20150296313 | HEARING AID - A hearing aid includes: a receiver having a side face with a sound outlet, and wherein a primary direction of the sound outlet is perpendicular to the side face; a hearing aid housing having an outer surface and an internal cavity configured for containing the receiver; a filter socket coupled to the hearing aid housing; and a filter releasably attached to the filter socket; wherein the filter socket defines a direction of detachment of the filter from the filter socket, and wherein the direction of detachment is arranged obliquely with respect to the primary direction of the sound outlet. | 10-15-2015 |
20150296314 | RECEIVER/LOUDSPEAKER - A hearing aid includes: a hearing aid housing; a receiver with a receiver housing, wherein the hearing aid housing comprises an internal cavity configured for containing the receiver; and an adapter having first mounting surfaces configured for holding the receiver, and second mounting surfaces configured for releasably attaching the adapter to a part of the hearing aid housing. | 10-15-2015 |
20150296315 | HEARING AID RECEIVER AND A HEARING AID COMPRISING SUCH A RECEIVER - A receiver for a hearing aid includes: a receiver housing having a side face with a sound opening; and a filter holder with a filter, wherein the filter holder is fastened to the receiver housing; wherein the filter holder has a bottom face, a first opening at the bottom face, a second opening configured for releasably mounting the filter to the filter holder, and a sound channel located between the first and second openings and aligned with the first opening; and wherein the bottom face of the filter holder abuts the side face of the receiver housing. | 10-15-2015 |
20150296316 | HEARING AID - A hearing aid includes: a hearing aid housing; a receiver; and a filter; wherein the hearing aid housing comprises an outer surface, a housing opening at the outer surface, and an internal cavity configured for containing the receiver; wherein the filter is insertable into the housing opening and is releasably mounted to the hearing aid housing; and wherein the housing opening is configured to provide sound emitted from the receiver, and wherein the housing opening and the receiver are relatively sized in order to allow for insertion of the receiver through the housing opening into the internal cavity for containment of the receiver in the internal cavity. | 10-15-2015 |
Johnny Johansen, Kobenhavn DK
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20110073806 | CONNECTED HEAT CONDUCTING STRUCTURES IN SOLID AMMONIA STORAGE SYSTEMS - A compacted block of material constructed of one or more units consisting of matter comprising an ammonia-saturated material capable of reversibly desorbing and ad- or absorbing ammonia surrounded by a gas-permeable, flexible material having a thermal conductivity of at least five times the thermal conductivity of said ammonia-saturated material at −70° C. to 250° C. and methods for producing the same are described. | 03-31-2011 |
20110236294 | Saturation of Ammonia Storage Materials in Containers - A method of saturating reversible ammonia storage materials inside a container for the purpose of achieving high volumetric ammonia storage capacity and containers filled with the materials are disclosed. | 09-29-2011 |
Johnny Johansen, København DK
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20100086467 | Release of Stored Ammonia at Start-Up - A system for storage and dosing of ammonia, including a solid ammonia storage material capable of binding and releasing ammonia reversibly by adsorption/absorption. The system is able to release ammonia gradually according to a demand that can vary over time with intermediate periods of no ammonia demand. A main storage unit and a start-up storage unit are provided. The storage units hold ammonia storage material. At least one one-way valve is provided via which the one main storage unit is in communication with the start-up storage unit. The one-way valve prevents any back-flow of ammonia from the start-up storage unit to the main storage unit. Heating devices are arranged to heat the main storage unit and the start-up storage unit separately to generate gaseous ammonia by thermal desorption from the solid storage material. A controller controls the heating power of the main storage unit and the start-up storage unit, thereby enabling ammonia release from at least one of the start-up and/or the main storage unit. A dosing valve controls ammonia flow from the storage units according to a demand. | 04-08-2010 |
Johnny Johansen, Kobenhavn S DK
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20100266475 | Production of Saturated Ammonia Storage Materials - A process for saturating a material capable of binding ammonia by ad- or absorption and initially free of ammonia or partially saturated with ammonia comprises treating said material under a pressure and associated temperature located on the vapor pressure curve of ammonia with an amount of liquid ammonia sufficient to saturate said material and an additional amount of a cooling agent selected from liquid ammonia, liquid or solid CO | 10-21-2010 |
20110218095 | Additives for Highly Compacted Ammonia Storage Materials - Disclosed is a self-supporting solid compacted composition of material comprising an ammonia storage material capable of reversibly absorbing and desorbing ammonia in its ammonia saturated state and compacted to such a density that it has of at least 70% of the single crystal density of said material in its ammonia-saturated state in admixture with one or more additive incapable of storing ammonia and having a thermal conductivity of at least five times the thermal conductivity of the ammonia storage material at a temperature of from at least −45° C. to 250° C., as well as a process for preparing it. | 09-08-2011 |
20110284121 | Method for Saturating and Re-Saturating Ammonia Storage Material in Containers - A method for saturating or re-saturating ammonia storage material ( | 11-24-2011 |
20120039788 | PRODUCTION OF SATURATED AMMONIA STORAGE MATERIALS - A process for saturating a solid material capable of binding ammonia by ad- or absorption and initially free of ammonia or partially saturated with ammonia comprises treating said solid material under a pressure and associated temperature located on the vapor pressure curve of ammonia with an amount of liquid ammonia sufficient to saturate said solid material and an additional amount of a cooling agent selected from liquid ammonia, liquid or solid CO | 02-16-2012 |
20120231949 | CONNECTED HEAT CONDUCTING STRUCTURES IN SOLID AMMONIA STORAGE SYSTEMS - A compacted block of material constructed of one or more units consisting of matter comprising an ammonia-saturated material capable of reversibly desorbing and ad- or absorbing ammonia surrounded by a gas-permeable enclosure made of a flexible material having a thermal conductivity of at least about five times the thermal conductivity of said ammonia-saturated material at −70° C.. to 250° C.. and methods for producing the same are described. | 09-13-2012 |
20130209316 | METHOD FOR DETERMINING THE DEGREE OF SATURATION OF SOLID AMMONIA STORAGE MATERIALS IN CONTAINERS - A method is provided for estimating the degree of saturation (S) of a reversible solid ammonia storage material ( | 08-15-2013 |
Jørn Johansen, Herlev DK
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20130161862 | Moulding Chamber Arrangement for a Mould-String Plant - Moulding chamber arrangement ( | 06-27-2013 |
Julia Johansen, Frederiksberg DK
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20110045518 | YKL-40 AS A GENERAL MARKER FOR NON-SPECIFIC DISEASE - The present invention relates to methods of diagnosing the presence of a non-specific disease or disorder in a subject, wherein a determined level of YKL-40 above a reference level indicates the presence of a non-specific disease or disorder. The subject may suffer from a variety of diseases or disorders. The reference level may be a reference level obtained from healthy individuals or it may be a previous measurement obtained from the same subject. The present invention furthermore relates to a method for classifying the severity of a non-specific disease or disorder in a subject, wherein a determined level of YKL-40 above or below one or more reference levels gives the severity of said non-specific disease or disorder. The present invention further relates to a kit and a device that may be used in the method of the present invention comprising means for measuring the level of YKL-40 in a sample; and means for comparing the measured level of YKL-40 with at least one reference level of YKL-40. | 02-24-2011 |
Julia Sidenius Johansen, Frederiksberg DK
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20120040354 | METHODS OF CLASSIFYING THE SEVERITY OF DISEASES OR DISORDERS - The present invention relates to methods of classifying the severity of a non-specific disease or disorder in a subject, wherein a determined level of YKL-40 is compared to one or more reference levels of YKL-40, and the severity of said non-specific disease or disorder is deduced from said comparison. The present invention furthermore relates to a method of classifying the severity of a disease or disorder in a subject, wherein a determined level of YKL-40 is compared to one or more previously determined levels of YKL-40 from the same subject. In both methods, the subject may suffer from a variety of diseases or disorders. In addition the present invention relates to a kit and a device that may be used in the methods of the present invention comprising means for measuring the level of YKL-40 in a sample; and means for comparing the measured level of YKL-40 with one or more reference levels of YKL-40. | 02-16-2012 |
20120040355 | YKL-40 AS A MARKER FOR SELECTION OF TREATMENT AND MONITORING OF A DISEASE - The present invention relates to a methods for selecting a treatment for a specific disease or disorder, together with a method of monitoring therapeutic treatment of a specific disease or disorder and a method of determining a prognosis for a subject before, during and after administering a treatment by determining the level of YKL-40 in a sample obtained from the subject and comparing said level with one or more reference levels of YKL-40. The reference level is typically a level obtained from healthy individuals or a level previously obtained from the same subject. The present invention further relates to a kit and a device that may be used in the methods of the present invention. | 02-16-2012 |
20120070853 | YKL-40 AS A MARKER FOR GASTROINTESTINAL CANCERS - The present invention relates to gastrointestinal cancers and methods for selecting a treatment for said gastrointestinal cancer in a subject. The present invention further relates to a methods of diagnosing the presence of and/or classifying the severity of a gastrointestinal cancer; together with methods for determining the effect of a therapy administered and/or the prognosis for a subject suffering from a gastrointestinal cancer, before, during or after administering the treatment. For all the methods applies that a determined level of YKL-40 above one or more reference levels indicates the treatment, the severity of the disease, the effect of the treatment and/or the prognosis of the subject. The reference level is typically a level obtained from healthy individuals or a level previously obtained from the same subject. The subject may suffer from any one or more gastrointestinal cancers, such as upper gastrointestinal cancers, and metastatic colorectal cancer. The present invention further relates to a kit and a device that may be used in the method of the present invention. | 03-22-2012 |
20130310276 | MICRORNA FOR DIAGNOSIS OF PANCREATIC CANCER - The present invention relates to methods for improving the diagnosis of pancreatic and ampullary adenocarcinomas by making use of specific mi RNA biomarkers and/or mi RNA classifiers. | 11-21-2013 |
20140106985 | MICRORNA BIOMARKERS FOR PROGNOSIS OF PATIENTS WITH PANCREATIC CANCER - The present invention relates to prognostic micro RNA (miRNA) biomarkers based on a specific miRNA expression pattern, which can prove as a valuable prognostic tool to predict the survival of patients being diagnosed with pancreas cancer. | 04-17-2014 |
20150152503 | MICRORNAS FOR PREDICTION OF TREATMENT EFFICACY AND PROGNOSIS OF CANCER PATIENTS - The present invention lies within the field of personalised medicine. More particular the invention relates to biomarkers useful for predicting treatment efficacy and prognosis in cancer patients. Thus the invention provides microRNAs (miRNAs) which are useful for predicting efficacy of anti-angiogenic treatment. In particular, miR-664 for the prediction of response to bevacizumab in colorectal cancer of sigmoid colon or rectum. | 06-04-2015 |
Katja S. Johansen, Gentofte DK
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20130012424 | Pectate Lyase Variants - The present invention relates to pectate lyase variants exhibiting alterations relative to a parent enzyme exhibiting pectate lyase activity as its major enzymatic activity; to a method of producing such enzymes; and to methods for using such enzymes in the textile, detergent and cellulose fiber processing industries. Compared to the parent enzyme, the pectate lyase variants of the present invention exhibit improved stability in detergents. | 01-10-2013 |
Katja Salomon Johansen, Gentofte DK
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20080280325 | Polypeptides Having Endoglucanase Activity and Polynucleotides Encoding Same - The present invention relates to isolated polypeptides having endoglucanase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides. | 11-13-2008 |
20090247448 | Pectate Lyase Variants - The present invention relates to pectate lyase variants exhibiting alterations relative to a parent enzyme exhibiting pectate lyase activity as its major enzymatic activity; to a method of producing such enzymes; and to methods for using such enzymes in the textile, detergent and cellulose fiber processing industries. Compared to the parent enzyme, the pectate lyase variants of the present invention exhibit improved stability in detergents. | 10-01-2009 |
20110201082 | POLYPEPTIDES HAVING ENDOGLUCANASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME - The present invention relates to isolated polypeptides having endoglucanase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides. | 08-18-2011 |
20130183723 | "Compositions Comprising A Polypeptide Having Cellulolytic Enhancing Activity And An Organic Compound And Uses Thereof" - The present invention relates to compositions comprising: a polypeptide having cellulolytic enhancing activity and an organic compound. The present invention also relates to methods of using the compositions. | 07-18-2013 |
20130273198 | Preparation of Baked Product From Dough - The present invention relates to a method for producing a baked product comprising preparing a dough comprising at least whole meal flour, a GH61 polypeptide, and a cellulase, and baking the dough to form the baked product. The present invention relates also to a baking composition comprising a GH61 polypeptide, a cellulase, and optionally flour. The present invention relates also to the use of a GH61 polypeptide and a cellulase for producing a baked product, e.g. a baked product, prepared from whole meal flour. | 10-17-2013 |
20140005093 | Pectate Lyase Variants | 01-02-2014 |
20140127771 | Methods of Increasing the Cellulolytic Enhancing Activity of a Polypeptide - The present invention relates to methods of increasing the activity of a GH61 polypeptide having cellulolytic enhancing activity, comprising: adding a divalent copper cation to a composition comprising the GH61 polypeptide having cellulolytic enhancing activity, wherein the presence of the divalent copper cation and the GH61 polypeptide having cellulolytic enhancing activity increases degradation or conversion of a cellulosic material by an enzyme composition compared to the GH61 polypeptide having cellulolytic enhancing activity without the divalent copper cation. The present invention also relates to compositions, methods for degrading or converting a cellulosic material, and methods for producing a fermentation product. | 05-08-2014 |
20150125909 | Compositions Comprising A Polypeptide Having Cellulolytic Enhancing Activity And An Organic Compound And Uses Thereof - The present invention relates to compositions comprising: a polypeptide having cellulolytic enhancing activity and an organic compound. The present invention also relates to methods of using the compositions. | 05-07-2015 |
20150315622 | Methods of Saccharifying and Fermenting a Cellulosic Material - The invention relates to methods of saccharifying a cellulosic material comprising subjecting the cellulosic material to a cellulolytic enzyme composition and a GH61 polypeptide, and optionally a catalase in the presence of dissolved oxygen at a concentration in the range of 0.5 to 10% of the saturation level. The invention also related to methods of producing desired fermentation products, such as ethanol, using a method including a saccharification step of the invention. | 11-05-2015 |
Katja Salomon Johansen, Bagsvaerd DK
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20150353907 | Methods of Increasing the Cellulolytic Enhancing Activity of a Polypeptide - The present invention relates to methods of increasing the activity of a GH61 polypeptide having cellulolytic enhancing activity, comprising: adding a divalent copper cation to a composition comprising the GH61 polypeptide having cellulolytic enhancing activity, wherein the presence of the divalent copper cation and the GH61 polypeptide having cellulolytic enhancing activity increases degradation or conversion of a cellulosic material by an enzyme composition compared to the GH61 polypeptide having cellulolytic enhancing activity without the divalent copper cation. The present invention also relates to compositions, methods for degrading or converting a cellulosic material, and methods for producing a fermentation product. | 12-10-2015 |
Keld Johansen, Frederikssund DK
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20090260346 | METHOD FOR PURIFICATION OF AN EXHAUST GAS FROM A DIESEL ENGINE - A method for removing impurities in exhaust gas from a diesel engine, where the impurities comprise nitrogen oxides, carbon monoxide, particulate matter and incompletely combusted hydrocarbons. The method comprises the steps of injection of a reductant comprising urea or ammonia into the exhaust gas from the engine, selective catalytic reduction of the nitrogen oxides in the exhaust gas by the reductant, and intermittent injection of a hydrocarbon into this effluent. The succeeding steps are oxidation of carbon monoxide, particulate matter, incompletely combusted hydrocarbons and injected hydrocarbon to carbon dioxide and water, and in selectively oxidising possible excess of reductant to free nitrogen, and finally filtration of the effluent by passing the gas through a catalysed filter. The remaining particulate matter is retained in the filter, and the carbon monoxide, particulate matter and hydrocarbons are oxidixed to carbon dioxide and water, and the reductant is selectively oxidixed to nitrogen, creating a purified exhaust gas. | 10-22-2009 |
20130210609 | METHOD FOR THE PREPARATION OF A CATALYSED PARTICULATE FILTER AND CATALYSED PARTICULATE FILTER - Method for the preparation of a catalysed particulate filter and a particulate filter. The method comprises the steps of a) providing a catalyst wash coat with a first catalyst active in burning off of soot and a second catalyst active in selective catalytic reduction of nitrogen oxides; b) coating a particulate filter body with the catalyst wash coat on the dispersion side and the permeate side of the filter body and within partition walls of the filter body; and c) drying and heat treating the coated filter body to obtain the catalysed particulate filter. | 08-15-2013 |
20130216439 | METHOD FOR THE PREPARATION OF A CATALYSED PARTICULATE FILTER AND CATALYSED PARTICULATE FILTER - Method for the preparation of a catalysed particulate filter and a particulate filter prepared by the method. | 08-22-2013 |
20130216441 | METHOD FOR THE PREPARATION OF A CATALYSED PARTICULATE FILTER AND CATALYSED PARTICULATE FILTER - The invention pertains to a catalysed particulate filter provided in its entire dispersion side and within its partition walls with a first catalyst being active in selective catalytic reduction of nitrogen oxides, and in its entire permeate side with a second catalyst combination with a catalyst being active in oxidation of ammonia mixed with a catalyst being active in oxidation of carbon monoxide and hydrocarbons and a method for its preparation. The mean particle size of the first catalyst is smaller than the mean pore diameter of the longitudinal porous walls, and the mean particle size of the second catalyst combination is larger than the mean pore diameter of the longitudinal walls. In the example, the first catalyst is a silica aluminium phosphate SAPO-34 promoted with 2% copper and the second catalyst is a mixture of platinum and palladium (molar ratio 3:1) supported on alumina particles and beta zeolite powder with 1.0% copper. | 08-22-2013 |
20140134063 | METHOD FOR COATING A CATALYSED PARTICULATE FILTER AND A PARTICULATE FILTER - Method for the preparation of a wall flow particulate filter catalysed at its inlet side with a first catalyst having activity in the removal of residual hydrocarbons and carbon monoxide and catalysing at rich burn engine operation conditions the reaction of nitrogen oxides with hydrogen and/or carbon monoxide to ammonia and catalysed at its outlet side with a second catalyst having activity in the selective reduction of NOx by reaction with ammonia being formed in the inlet side. The method involves the provision of a first catalyst having a particle size larger than the filter wall mean pore size, and a second catalyst having a particle size smaller than the filter wall mean pore size, and mixing the first and second catalyst into one suspension, which is used for wash-coating from the inlet end. The second catalyst thereby diffuses into the partition wall. | 05-15-2014 |
20140140899 | CATALYSED PARTICULATE FILTER AND METHOD FOR THE PREPARATION OF A CATALYSED PARTICULATE FILTER - Wall flow particulate filter catalysed at its inlet side with a catalyst having activity in the removal of residual hydro-carbons and carbon monoxide and catalysing at rich burn engine operation conditions the reaction of nitrogen oxides with hydrogen and/or carbon monoxide to ammonia and catalysed at its outlet side with a catalyst having activity in the selective reduction of NOx by reaction with ammonia being formed in the inlet side. | 05-22-2014 |
20140170033 | METHOD FOR COATING A CATALYSED PARTICULATE FILTER AND A PARTICULATE FILTER - Method for the preparation of a wall flow particulate filter catalysed at its inlet side with a first catalyst having activity in the removal of residual hydrocarbons and carbon monoxide and catalysing at rich burn engine operation conditions the reaction of nitrogen oxides with hydrogen and/or carbon monoxide to ammonia and catalysed at its outlet side with a second catalyst having activity in the selective reduction of NOx by reaction with ammonia being formed in the inlet side. The method involves the provision of a first catalyst having a particle size smaller than the filter wall mean pore size, and a second catalyst having a particle size larger than the filter wall mean pore size, and mixing the first and second catalyst into one suspension, which is used for wash-coating from the outlet end. The first catalyst thereby diffuses into the partition wall. | 06-19-2014 |
20150020506 | METHOD AND SYSTEM FOR THE REMOVAL OF NOXIOUS COMPOUNDS FROM ENGINE EXHAUST GAS - Method and system for the removal of noxious compounds from lean burning engines, the method comprising in series the steps of contacting the exhaust gas with a catalyst being active in oxidation of volatile organic compounds and carbon monoxide, passing the treated exhaust gas through a particulate filter catalysed with a first SCR catalyst, and passing the exhaust gas leaving the particulate filter through a second SCR catalyst, wherein ammonia is injected into the exhaust upstream of the catalysed particulate filter at a temperature below or at about 220° C. and wherein urea is injected into the exhaust gas between the first and the second SCR catalyst when the exhaust gas has reached a temperature of about 200° C. | 01-22-2015 |
20150224477 | METHOD FOR THEPREPARATION OF A CATALYSED PARTICULATE FILTER AND CATALYSED PARTICULATE FILTER - A catalysed particulate filter coated with a wash coat on its dispersion side and its permeate side and within partition walls of the filter. The wash coat contains a first catalyst active in burning off soot, together with a second catalyst active in a selective catalytic reduction of nitrogen oxides. | 08-13-2015 |
Keld Johansen, Sundbylille DK
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20110283680 | METHOD FOR PURIFICATION OF EXHAUST GAS FROM A DIESEL ENGINE - The invention provides a method for purification of exhaust gas from a diesel engine in a system, which comprises a device for selective catalytic reduction and a diesel particulate filter preferably at least partially covered by a catalytic layer installed downstream of the device for selective catalytic reduction. A device for catalytic oxidation is installed upstream of the device for selective catalytic reduction and/or between the device for selective catalytic reduction and the diesel particulate filter. A device for injection of a controlled amount of reductant is installed inlet of the device for selective catalytic reduction, and a device for injection of a controlled amount of hydrocarbon is installed inlet of the catalytic oxidation. | 11-24-2011 |
20120183460 | PROCESS AND APPARATUS FOR PURIFICATION OF AN EXHAUST GAS FROM AN INTERNAL COMBUSTION ENGINE - The invention provides a process for purification of an exhaust gas comprising nitrogen oxides, carbon monoxide, hydrocarbons and particulate matters from an internal combustion engine comprising the step of contacting the exhaust gas with one or more catalysts on one or more cross corrugated wire mesh sheets ( | 07-19-2012 |
Kenneth Hojrup Johansen, Lyngby DK
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20110100910 | CERAMIC DEAD-END FILTER, A FILTER SYSTEM, A METHOD OF FILTERING AND A METHOD OF PRODUCING A CERAMIC DEAD-END FILTER - The invention relates to a ceramic dead-end filter for filtration of liquid. The ceramic dead-end filter comprises at least one ceramic filter membrane having a first side with a front surface and a second side. The ceramic membrane comprises a selective front layer providing said front surface and the selective front layer comprises a maximum pore size diameter of about μm or smaller, for example between about 0.5 nm and about 25 μm. The ceramic dead-end filter of the invention provides an effective filtration with a high flux and a long durability. The filter can furthermore be regenerated in a simple way. The invention also relates to filtration system comprising such ceramic dead-end filter, a method of performing the filtration process as well as a method of producing the filter. | 05-05-2011 |
Lars Johansen, Kobenhavn DK
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20110189749 | TRAPPING, RECYCLING, AND OTHER TECHNIQUES INVOLVING CATALYSTS - Trapping, recycling, and other techniques involving catalysts are provided by this invention. The present invention provides for the retention of catalysts and other immobilized entities within a reaction region. In one aspect, the invention promotes such retention by incorporating support material regions including relatively little (or, in some cases, substantially no) catalyst (and thus, a relatively large number of catalyst adsorption sites) which can trap catalyst as it is transported through the downstream support material. In some cases, such arrangements can be achieved by using multiple beds arranged in series. In other instances, the amount of catalyst can be varied within a single bed to achieve the desired effect. The embodiments described herein can be used in systems in which the catalyst is covalently or non-covalently associated with the support surface. | 08-04-2011 |
Leif Steen Johansen, Bronshoj DK
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20090067659 | Miniature microphone assembly with hydrophobic surface coating - A miniature microphone assembly comprises a capacitive-microphone transducer, a microphone carrier, and an integrated circuit die. The capacitive-microphone transducer includes a microphone-electrical contact or terminal. The microphone carrier comprises a carrier electrical contact or terminal formed on a first surface of the microphone carrier. An integrated circuit die includes a die electrical terminal operatively coupled to signal amplification or signal conditioning circuitry of the integrated circuit die. The first surface of the microphone carrier comprises a hydrophobic layer or coating. The side surfaces of the integrated circuit die and/or the capacitive-microphone transducer may also include the hydrophobic layer or coating. | 03-12-2009 |
20140035434 | MEMS Device Comprising An Under Bump Metallization - The present invention concerns a MEMS device comprising an under bump metallization ( | 02-06-2014 |
Leif Steen Johansen, Brønshøj DK
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20090214061 | Miniature Microphone Assembly With Solder Sealing Ring - The present invention relates to a miniature microphone assembly comprising a capacitive microphone transducer comprising a microphone electrical contact or terminal, a microphone carrier comprising a carrier electrical contact or terminal formed on a first surface thereof, and an integrated circuit die comprising a die electrical terminal operatively coupled to signal amplification or signal conditioning circuitry of the integrated circuit die. The first surface of the microphone carrier comprises a first electrically conductive path surrounding the carrier electrical contact or terminal. | 08-27-2009 |
Lisbeth Hoj Johansen, Horsens DK
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20090246318 | COMPOSITION - A dough is described. The dough has a high percentage of rye flour. | 10-01-2009 |
Marianne Gregers Johansen, Arhus C DK
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20100138940 | TRANSGENIC PIG AS A MODEL OF ALZHEIMER'S DISEASE - The present invention relates to a modified pig as a model for studying Alzheimer's disease. The modified pig model displays one or more phenotypes associated with Alzheimer's disease. Disclosed is also a modified pig comprising a modified human and/or porcine APP gene, and/or PS1 gene, and/or a transcriptional and/or translational product or part thereof. The invention further relates to methods for producing the modified pig; and methods for evaluating the effect of a therapeutical treatment of Alzheimer's disease; methods for screening the efficacy of a pharmaceutical composition; and a method for treatment of a human being suffering from Alzheimer's disease are disclosed. | 06-03-2010 |
Martin Johansen, Copenhagen DK
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20090163239 | METHOD, APPARATUS AND COMPUTER PROGRAM PRODUCT FOR GENERATING MEDIA CONTENT BY RECORDING BROADCAST TRANSMISSIONS - An apparatus for enabling generation of media content by recording broadcast transmissions may include a processing element. The processing element may be configured to record content associated with a broadcast transmission at a mobile terminal, assign an informational tag to the recorded content without user interaction during the assigning, and store the recorded content in association with the informational tag. | 06-25-2009 |
Martin Johansen, Vejle DK
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20120245905 | SYSTEMS AND METHODS FOR PREDICTING FLUID DYNAMICS IN A DATA CENTER - A system and method for predicting airflow within a data center using a potential flow technique is provided. In one aspect, a method includes automatically generating an unstructured grid, the unstructured grid comprising a plurality of unstructured grid cells, each unstructured grid cell having a size, dividing a representation of the data center into the plurality of unstructured grid cells, determining airflow velocity values for each of the plurality of unstructured grid cells using airflow velocity potentials, determining a temperature value for each one of the plurality of the unstructured grid cells using the airflow velocity values, determining a concentration value for each of the plurality of the unstructured grid cells using the airflow velocity values, and calculating a comparison result indicating whether the concentration values, the airflow velocity values and the temperature values for the plurality of the unstructured grid cells satisfy convergence criteria. | 09-27-2012 |
Morlen Kjaer Johansen, Smorum DK
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20090296967 | HEARING AID SYSTEM WITH A LOW POWER WIRELESS LINK BETWEEN A HEARING INSTRUMENT AND A TELEPHONE - The invention relates to wireless communication between listening devices, in particular to a hearing aid system comprising a hearing instrument and a telephone apparatus. The invention further relates to a method of receiving a telephone call and to the use of a hearing aid system. The object of the present invention is to provide a relatively simple, reliable scheme for receiving a telephone call in a hearing instrument. The problem is solved in that the telephone apparatus comprises a transmitter for establishing a short range digital, low-power link to a hearing instrument comprising a corresponding receiver. This has the advantage of providing a relatively simple and low power solution, where at least the incoming part of a telephone conversation is wirelessly transmitted via a low-power link. The invention may e.g. be used for the communication between a hearing instrument and a telephone, where a standard wireless interface for local connectivity, such as a Bluetooth interface, is not technically feasible or not available for other reasons. | 12-03-2009 |
Morten Kjaer Johansen, Smorum DK
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20100329491 | SYSTEM FOR TRANSMITTING AMPLIFIED AUDIO SIGNALS TO A USER - Disclosed is a system for transmitting amplified audio signals to a user, wherein the system comprises a receiver unit, a transmitter unit and a base unit, wherein | 12-30-2010 |
Niels Langeland Johansen, Copenhagen O DK
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20100197573 | Transglutaminase Mediated Conjugation of Growth Hormone - A method for PEGylating growth hormone, said method comprising reacting growth hormone with an amine comprising nucleophile which further comprises a first functional group in the presence og TGase to form a transaminated growth hormone, followed by a reaction of said transaminated growth hormone with a PEG which has been functionalised with a second functional group, wherein said first and second functional groups are selected so that they react to form a covalent bond. | 08-05-2010 |
20130244931 | Novel GLP-1 Derivatives - Novel polypeptide derivatives having protracted profile of action. | 09-19-2013 |
Niels Thybo Johansen, Virum DK
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20090077405 | AUDIO-VISUAL SYSTEM ENERGY SAVINGS USING A MESH NETWORK - In embodiments of the present invention, improved capabilities are described for powering, controlling, and operating a home audio visual system using a mesh network that includes an energy savings mode based at least in part on intermittently powered mesh network nodes that are associated with the home audio-visual system. In embodiments, the intermittently powered mesh network nodes may periodically wake up, listen for wake up calls and/or initiate a full power mode in the home audio visual system when a intermittently power mesh network node is awakened and receives a subsequent full power instruction. Intermittently powered mesh network nodes may be further associated with instruction routing that utilizes silent acknowledgement. | 03-19-2009 |
20090082888 | AUDIO-VISUAL SYSTEM CONTROL USING A MESH NETWORK - In embodiments of the present invention, improved capabilities are described for a home audio-visual system that is at least in part controlled through a mesh network, wherein the home audio-visual system produces at least two effects. Each of the at least two effects may be controlled through separate mesh network nodes responsive to user initiated instructions. Each of the separate mesh network nodes may be adapted to receive the user initiate instructions through a channel management operation. In embodiments of the present invention, a home audio-visual system may communicate information through a mesh network, wherein the home audio-visual system includes one or more electrical devices that produce the information. The home audio-visual system may be associated with a channel management operation that is associated with one or more nodes of the mesh network to effect the communication of the information. In embodiments of the present invention, a media server may be enabled to control the delivery of a plurality of media content streams to a plurality of electrical devices, wherein the media server is adapted to be controlled through a mesh network node using a mesh network channel management operation. In embodiments, a command to the media server through the mesh network node may be transmitted in response to a user initiated instruction input to a hand held remote control, causing the mesh network node to receive the user initiated command through manipulation of a channel control operation. In embodiments, the media server may control the delivery of at least one of the plurality of media content streams to at least one of the plurality of electrical devices based on the user initiated command. | 03-26-2009 |
20100149967 | NODE REPAIR IN A MESH NETWORK - In embodiments of the present invention improved capabilities are described for sensing a change in a network topology using a discovery node in a mesh network; transmitting an explore frame, based at least in part on the sensed change, from the discovery node to a destination node using an intermediate node; receiving a response to the explore frame from the destination node; determining at least one functional network route from the discovery node to the destination node based at least in part on route information received in association with the response to the explore frame, wherein the route information includes a node path; and transmitting an instruction to the destination node from the discovery node based on a reverse node path. | 06-17-2010 |
20120155253 | NODE REPAIR IN A MESH NETWORK - In embodiments of the present invention improved capabilities are described for sensing a change in a network topology using a discovery node in a mesh network; transmitting an explore frame, based at least in part on the sensed change, from the discovery node to a destination node using an intermediate node; receiving a response to the explore frame from the destination node; determining at least one functional network route from the discovery node to the destination node based at least in part on route information received in association with the response to the explore frame, wherein the route information includes a node path; and transmitting an instruction to the destination node from the discovery node based on a reverse node path. | 06-21-2012 |
20120275343 | USING BATTERY-POWERED NODES IN A MESH NETWORK - In embodiments of the present invention improved capabilities are described for configuring a constant powered mesh network node to control a configuration of an intermittently powered mesh network node, where the intermittently powered mesh network node may include a repeater node that periodically powers down for a time period to conserve energy. The embodiments include transmitting a message beam to the repeater node, where a duration of the message beam length may exceed the time period that the repeater node is powered down, and where the message beam may contain a preamble with data that may indicate that the repeater node is to remain powered up in order to receive a message, and may cause the intermittently powered mesh network node to request configuration information relating to a network topology from the constant powered mesh network node when the intermittently powered mesh network node powers up. | 11-01-2012 |
20130142051 | Dynamically enabling a channel for message reception in a mesh network - In embodiments of the present invention improved capabilities are described for operating a node in a wireless mesh network to scan each one of a plurality of channels received at a processing node in a wireless mesh network in a predetermined order for a predetermined duration to detect a preamble; detect the preamble on one of the plurality of channels; remain on a current one of the plurality of channels to receive a message after the predetermined duration when the preamble includes a predetermined series of symbols; and resume scanning each one of the plurality of channels after the message is received. | 06-06-2013 |
20140098658 | NODE REPAIR IN A MESH NETWORK - In embodiments of the present invention improved capabilities are described for sensing a change in a network topology using a discovery node in a mesh network; transmitting an explore frame, based at least in part on the sensed change, from the discovery node to a destination node using an intermediate node; receiving a response to the explore frame from the destination node; determining at least one functional network route from the discovery node to the destination node based at least in part on route information received in association with the response to the explore frame, wherein the route information includes a node path; and transmitting an instruction to the destination node from the discovery node based on a reverse node path. | 04-10-2014 |
Nils Langeland Johansen, Koebenhavn Oe DK
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20120309944 | Growth Hormones With Prolonged In-Vivo Efficacy - The invention relates to growth hormone compounds with a protracted profile. The effect is obtained by linking an albumin binding residue via a hydrophilic spacer to growth hormone variants. Further described are methods of preparing and using such compounds. These growth hormone compounds are based on there altered profile considered particular useful in therapy. | 12-06-2012 |
20140107324 | Growth Hormones with Prolonged In-Vivo Efficacy - The invention relates to growth hormone compounds with a protracted profile. The effect is obtained by linking an albumin binding residue via a hydrophilic spacer to growth hormone variants. Further described are methods of preparing and using such compounds. These growth hormone compounds are based on there althered profile considered particular useful in therapy. | 04-17-2014 |
Nils Langeland Johansen, Koebenhavn O DK
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20120289453 | NOVEL GLP-1 COMPOUNDS - Novel GLP-1 compounds and their therapeutic use. | 11-15-2012 |
Nils Langeland Johansen, Kobenhavn O DK
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20100305032 | Novel GLP-1 Derivatives - Novel polypeptide derivatives having protracted profile of action. | 12-02-2010 |
20120172303 | Growth Hormones with Prolonged In-Vivo Efficacy - The present invention relates to polypeptide compound optimized for subcutaneous administration, exemplified by growth hormone conjugates having a linker providing non-covalent binding to albumin. | 07-05-2012 |
Nils Langeland Johansen, Kobenhavn DK
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20130053315 | NOVEL GLP-1 DERIVATIVES - Novel polypeptide derivatives having protracted profile of action. | 02-28-2013 |
Nils Langeland Johansen, Bagsvaerd DK
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20110263501 | Growth Hormone Conjugate with Increased Stability - Novel growth hormone conjugates comprising a growth hormone compound (GH) and a growth hormone binding protein (GHBP) are disclosed. The invention also encompasses a novel derivatization method for producing stable, long-lasting conjugate (hGH-GHBP) by site specific conjugation. The novel GH-GHBP conjugates have an extended half-life in circulation that facilitates therapeutic use of the protein. The GH-GHBP conjugates exhibit pharmacological properties such as increased functional in vivo half-life, improved renal filtration, improved protease protection and albumin binding. | 10-27-2011 |
Nils Langeland Johansen, Copenhagen DK
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20090117640 | Transglutaminase Variants with Improved Specificity - Variants of transglutaminase from | 05-07-2009 |
20090253166 | Conjugation of Peptides - Methods for the selective conjugation of peptides which comprises an enzymatic incorporation of a functional group at the C-terminal end of a peptide followed by reaction with a second compound comprising the moiety to be conjugated to the peptide, wherein said second compound comprises a functional group which selectively reacts with the incorporated functional group. | 10-08-2009 |
20090264366 | Transglutaminase Mediated Conjugation of Peptides - Methods for conjugating peptides are provided comprising i) reacting a peptide with a first compound comprising a functional group in the presence of a transglutaminase capable of incorporating said compound into the peptide to form a transaminated peptide, and ii) reacting said transaminated peptide with e.g. a functionalized polymer capable of reacting with the functional group incorporated in the peptide in the enzymatic reaction. | 10-22-2009 |
20100009917 | Modulating Enzymatic Processes by Addition of Diolcontaining Substances - The present invention relates to a method for increasing the selectivity of an enzyme, which method comprises performing the reaction in the presence of an enhancing compound selected from one of ethylene glycol, propylene glycol or glycerol. | 01-14-2010 |
Nils Langeland Johansen, Kobenhavn 0 DK
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20130040884 | ALBUMIN-BINDING CONJUGATES COMPRISING FATTY-ACID AND PEG - Novel polypeptide derivatives having protracted profile of action. | 02-14-2013 |
Nina Johansen, Rodovre DK
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20080274534 | Virus Filtration of Liquid Factor VII Compositions - The present invention relates to a novel method for improving the viral safety of liquid Factor VII compositions, in particular those comprising active Factor VII polypeptides (a Factor VIIa polypeptide). | 11-06-2008 |
20120115204 | VIRUS FILTRATION OF LIQUID FACTOR VII COMPOSITIONS - The present invention relates to a novel method for improving the viral safety of liquid Factor VII compositions, in particular those comprising active Factor VII polypeptides (a Factor VIIa polypeptide). | 05-10-2012 |
Nina Johansen, Roedovre DK
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20150299685 | Virus Filtration of Liquid Factor VII Compositions - The present invention relates to a novel method for improving the viral safety of liquid Factor VII compositions, in particular those comprising active Factor VII polypeptides (a Factor VIIa polypeptide). | 10-22-2015 |
Peter Johansen, Slagelse DK
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20130260976 | Laminate For Use In Packages, A Method Of Making A Reclosable Laminate And Use Thereof - A laminate for use in packages comprises a base layer ( | 10-03-2013 |
Peter Johansen, Odense C DK
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20150368018 | A CHILDPROOF BLISTER PACKAGE WITH CONTROLLED OPENING - The present invention relates to a blister package ( | 12-24-2015 |
Shanna Koltzen Johansen, Odense DK
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20100292137 | Antibiotics and Methods For Producing Them - The invention relates to cyclic peptides and methods for producing and using them. Provided is amongst others a method for determining whether a compound comprises antibiotic activity, the method comprising providing a cyclic peptide to a bacterium wherein a 23S rRNA in a 5OS ribosomal subunit does not comprises a 2′ O-methylation at a nucleotide that corresponds to nucleotide C 1920 in | 11-18-2010 |
Stefan Johansen, Sonderborg DK
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20130334807 | NANOFIBRE TAG - The present invention relates to the field of anti-counterfeit products. In particular, the invention is related to a method to produce anti-counterfeiting tags having unique nanofibre patterns. This unique nanofibres pattern is grown randomly at the edge of or underneath a masking means. | 12-19-2013 |
Teit E. Johansen, Stampeengen DK
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20080227703 | Novel Neurotrophic Factors - The invention relates to neublastin neurotrophic factor polypeptides, nucleic acids encoding neublastin polypeptides, and antibodies that bind specifically to neublastin polypeptides, as well as methods of making and methods of using the same. | 09-18-2008 |
20100234293 | Novel Neurotrophic Factors - The invention relates to neublastinneurotrophic factor polypeptides, nucleic acids encoding neublastin polypeptides, and antibodies that bind specifically to neublastin polypeptides, as well as methods of making and methods of using the same. | 09-16-2010 |
Teit E. Johansen, Horsholm DK
Patent application number | Description | Published |
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20080233647 | NOVEL NEUROTROPHIC FACTORS - The invention relates to neublastin neurotrophic factor polypeptides, nucleic acids encoding neublastin polypeptides, and antibodies that bind specifically to neublastin polypeptides, as well as methods of making and methods of using the same. | 09-25-2008 |
20090087474 | Therapeutic use of growth factors,nsg29 and nsg31 - The present invention relates to the field of therapeutic use of proteins, genes and cells, in particular to the therapy based on secreted therapeutic proteins, NsG29 and NsG31. NsG29 and Ns31 are members of a newly identified family of growth factors with a specific cystein pattern and characterised by expression in the nervous system. The secreted growth factors have potential for the treatment of disorders of the nervous system. The invention also relates to bioactive NsG29 and NsG31 polypeptide fragments and the corresponding encoding DNA sequences. | 04-02-2009 |
20090136552 | Growth factors nsg28, nsg30, and nsg32 - Disclosed are NsG28, NsG30, NsG32 polypeptides, nucleic acids encoding NsG28, NsG30, NsG32 polypeptides, and antibodies that bind to NsG28, NsG30, NsG32 polypeptides as well as methods of making and using the same. | 05-28-2009 |
20100292142 | NOVEL NEUROTROPHIC FACTORS - The invention relates to neublastin neurotrophic factor polypeptides, nucleic acids encoding neublastin polypeptides, and antibodies that bind specifically to neublastin polypeptides, as well as methods of making and methods of using the same. | 11-18-2010 |
20110112035 | THERAPEUTIC USE OF A GROWTH FACTOR, METRNL - The present invention relates to the field of therapeutic use of proteins, genes and cells, in particular to the therapy based on the biological function of a secreted therapeutic protein, METRNL, in particular for the treatment of disorders of the nervous system. METRNL is a Nerve Survival and Growth factor with neuroprotective and/or neurogenesis effects. | 05-12-2011 |
20120021039 | EXPRESSION OF NEUROPEPTIDES IN MAMMALIAN CELLS - The present application relates to expression constructs capable of securing correct processing of neuropeptides upon expression in mammalian cells, and to mammalian cells secreting correctly processed peptides. One exemplary peptide is galanin. The application also relates to devices containing neuropeptide secreting cells, which devices may be used for the treatment of epilepsy and other disorders of the nervous system. All references cited herein are incorporated by reference. | 01-26-2012 |
20120108518 | TREATMENT OF ALLODYNIA, HYPERALGESIA, SPONTANEOUS PAIN AND PHANTOM PAIN - The present invention relates to the use of Meteorin for the treatment of allodynia, hyperalgesia, spontaneous pain and phantom pain. In a preferred embodiment the disorder to be treated is allodynia, and hyperalgesia, more preferably allodynia including thermal and tactile allodynia. | 05-03-2012 |
20120184492 | THERAPEUTIC USE OF A GROWTH FACTOR, NSG33 - The present invention relates to the field of therapeutic use of proteins, genes and cells. More specifically the invention relates to therapy based on the biological function of a secreted therapeutic protein, NsG33, in particular for the treatment of disorders of the nervous system. NsG33 is a nerve survival and growth factor with antiapoptotic effects on a cell line with neuronal potential and with neuroprotective and/or neurogenesis effects on a neural precursor cell line and on primary striatal cultures. The invention also relates to novel bioactive NsG33 polypeptide fragments and the corresponding encoding DNA sequences. | 07-19-2012 |
20120252726 | NOVEL NEUROTROPHIC FACTORS - The invention relates to neublastin neurotrophic factor polypeptides, nucleic acids encoding neublastin polypeptides, and antibodies that bind specifically to neublastin polypeptides, as well as methods of making and methods of using the same. | 10-04-2012 |
20130109624 | NOVEL NEUROTROPHIC FACTORS | 05-02-2013 |
20130267464 | THERAPEUTIC USE OF A GROWTH FACTOR, METRNL - The present invention relates to the field of therapeutic use of proteins, genes and cells, in particular to the therapy based on the biological function of a secreted therapeutic protein, METRNL, in particular for the treatment of disorders of the nervous system. METRNL is a Nerve Survival and Growth factor with neuroprotective and/or neurogenesis effects. | 10-10-2013 |
20150231208 | Treatment of Allodynia, Hyperalgsia, Spontaneous Pain, and Phantom Pain - The present invention relates to use of Cometin in a method of treatment of allodynia, hyperalgesia, spontaneous pain and/or phantom pain. In a preferred embodiment the disorder to be treated is thermal allodynia and thermal hyperalgesia. The Cometin polypeptide may be delivered as a polypeptide or by administration of an expression vector for expression of Cometin, a cell line transformed or transduced with said vector and a capsule comprising said cells. | 08-20-2015 |
Thais T. Johansen, Vedbaek DK
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20090117558 | Method for improved specificity in probe based assays - Disclosed are compositions and methods for analyzing a target sequence in a sample. Generally, the method includes use of at least one pair of probes (Probe A and Probe B). In one embodiment, Probe A hybridizes to wanted and unwanted nucleic acid in the sample and bears a fluorophore and Probe B hybridizes to unwanted nucleic acid in the sample and bears a quencher. Fluorescence signal from Probe A hybridizing to unwanted nucleic acid is quenched by any relatively close hybridization of Probe B hereby increasing the specificity for the presence, amount or absence of the wanted target sequence. In preferred embodiments, the method is referred to as Fluorescence In-Situ Hybridization (FISH). The invention has many useful applications including rapidly detecting a microbial target sequence in a clinical sample. | 05-07-2009 |
20090143237 | Methods, kits and compositions pertaining to fluorescence quenching using pna probes - Disclosed for instance, are methods suitable for the detection, identification and/or quantitation of nucleic acid target sequences using probes. Suitable probes include those consisting of peptide nucleic acid (PNA) or locked nucleic add (LNA) units. Binding of the probes to adjacent target sequences results in fluorescent quenching. Analysis of changes in the fluorescent signal is used to detect, identify or quantitate a target sequence in a sample. The invention is more specifically directed to methods for improving the sensitivity, specificity and/or reliability of diagnostic tests using suitable probes. It is particularly well-suited for real-time PCR and related amplification reaction. | 06-04-2009 |
Thue Johansen, Koebenhavn Oe DK
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20130261051 | Treating Diabetes Melitus Using Insulin Injections Administered With Varying Injection Intervals - The present invention relates to methods for treatment of a condition or disease where administration of insulin will be of benefit, comprising administering, to a patient in need thereof, effective dosages of an insulin, insulin analogue or derivative thereof, which exhibits a prolonged profile of action, wherein said dosages are administered at intervals of varying length. | 10-03-2013 |
20150126439 | PHARMACEUTICAL COMPOSITION - A combination comprising at least a first insulin-like compound and a second insulin-like compound for treating a condition or a disease in a subject in need thereof where administration of insulin would be of benefit to said subject is described. The combination is administered in an amount to achieve a beneficial glycaemic control in said subject as determined by the levels of HbA | 05-07-2015 |
Thue Johansen, Copenhagen ø DK
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20110230402 | TREATING DIABETES MELITUS USING INSULIN INJECTIONS WITH LESS THAN DAILY INJECTION FREQUENCY - The present invention relates to an insulin derivative for the treatment of a condition or disease where administration of insulin will be of benefit, comprising administering, to a patient in need thereof, effective dosages of the insulin derivative, wherein said insulin derivative exhibits a prolonged profile of action and wherein said dosages are administered at intervals longer than 24 hours. | 09-22-2011 |
Tina Holm Johansen, Amorum DK
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20100280087 | NOVEL 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS - This invention relates to novel 2-amino benzimidazole derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention. | 11-04-2010 |
Troels Johansen, Nivaa DK
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20090118687 | Set of Coupling Parts - The present invention relates to a set of coupling parts, such as parts for coupling an ostomy bag to a base plate, said base plate being adhered around a stoma. The set of coupling parts provides a set of coupling parts wherein a connection part may be interposed between a first coupling part and a second coupling part and where the coupling parts may be connected and disconnected from each other by the same movement of the connection part. | 05-07-2009 |
20110137273 | Fecal management system - The present invention relates to a fecal management system for collecting fecal matter from the rectum. The system comprises a first fecal receiving bag and a second fecal receiving bag having an elongated section extending in a flow direction between a second proximal opening and a reservoir section, wherein the first fecal receiving bag and the second fecal receiving bag are connectable to each other. This provides a fecal management system that is adaptable to the user; e.g. the first fecal receiving bag can be produced as a compact and portable device, which allows for the user to move around as fecal matter will be collected in the first fecal receiving bag and thereby avoiding any embarrassing accidents; and when the user lies in bed the second fecal receiving bag can be coupled to the first fecal receiving bag, which allows for additional capacity for collecting e.g. nightly stools. | 06-09-2011 |
Troels Johansen, Aarhus C DK
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20120240935 | MEDICAL BREATHING MASK - A facial breathing mask suitably for regulating the carbon dioxide concentration in the inspired air, the facial mask comprising an air chamber with an opening through which a user can breathe. At least a part of the air chamber is flexible and/or collapsible and comprises one or more of semi-permeable membranes separating the air chamber and a surrounding atmosphere. | 09-27-2012 |