Patent application number | Description | Published |
20110116700 | ADAPTIVE GRADIENT WEIGHTING TECHNIQUE FOR DETECTOR BAD CELL CORRECTION - An imaging system includes a two-dimensional detector having a plurality of cells wherein each cell is configured to detect energy or signal passing through an object. The imaging system includes a computer programmed to acquire imaging data for the plurality of cells, identify a cell to be corrected, based on the imaging data, interpolate I | 05-19-2011 |
20110142314 | SYSTEM AND METHOD OF INCREASING TEMPORAL RESOLUTION OF AN X-RAY IMAGE - A system, method, and apparatus includes a computed tomography (CT) system having a rotatable gantry, an x-ray source, a generator, a detector having pixels and positioned to receive x-rays, and a computer. The computer is programmed to acquire CT data representative of an object, determine a first subset of the CT data, determine a second subset of the CT data, and determine a difference between the first and second subsets of the CT data to identify a motion region in the object. The computer is also programmed to update image data reconstructed from a first portion of the first subset of the CT data and corresponding to the region and reconstruct an image based on the updated image data and non-updated image data. The non-updated image data is reconstructed from a second portion the first subset of the CT data. | 06-16-2011 |
20110150174 | MULTIPLE X-RAY TUBE SYSTEM AND METHOD OF MAKING SAME - An imaging system includes a rotatable gantry having an opening therein to receive a subject to be scanned and configured to rotate about a central axis in a rotation direction. The imaging system also includes a first x-ray source coupled to the rotatable gantry at a first position, wherein the first position is offset from the central axis of the rotatable gantry by a first distance. Further, the imaging system includes a second x-ray source coupled to the rotatable gantry at a second position, wherein the second position is offset from the central axis of the rotatable gantry by a second distance, wherein the second position is offset from the first position in a direction coincident with the rotation direction, and wherein the second position is offset from the first position in a direction parallel to the central axis. | 06-23-2011 |
20110158498 | NOISE REDUCTION METHOD FOR DUAL-ENERGY IMAGING - A method is provided that includes acquiring a first set of image data from X-rays produced at a first energy level and a second set of image data from X-rays produced at a second energy level. The method includes generating a first noise mask for a first basis material and a second noise mask for a second basis material and removing pixels corresponding to cross contaminating structural information from the first noise mask and the second noise mask. The method includes processing a first materially decomposed image generated from the first set of image data and the second set of digital data using the second noise mask after removal of the cross contaminating structural information and processing a second MD image generated from the first set of image data and the second set of digital data using the first noise mask after removal of the cross contaminating structural information. | 06-30-2011 |
20120314928 | SYSTEM AND METHOD OF INCREASING TEMPORAL RESOLUTION OF AN X-RAY IMAGE - A system, method, and apparatus includes a computed tomography (CT) system having a rotatable gantry, an x-ray source, a generator, a detector having pixels and positioned to receive x-rays, and a computer. The computer is programmed to acquire CT data representative of an object, determine a first subset of the CT data, determine a second subset of the CT data, and determine a difference between the first and second subsets of the CT data to identify a motion region in the object. The computer is also programmed to update image data reconstructed from a first portion of the first subset of the CT data and corresponding to the region and reconstruct an image based on the updated image data and non-updated image data. The non-updated image data is reconstructed from a second portion the first subset of the CT data. | 12-13-2012 |
Patent application number | Description | Published |
20110311474 | Novel Tricyclic Compounds - The invention provides compounds of Formula (I) and Formula (II) | 12-22-2011 |
20140349970 | NOVEL TRICYCLIC COMPOUNDS - The invention provides a compound of Formula (Ia), (Ib), (Ic), (Id), (Ie), (If), (Ig), (Ih), (Ii), (Ij), (Ik), or (Il) as defined herein, pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions. | 11-27-2014 |
Patent application number | Description | Published |
20090312338 | Novel Tricyclic Compounds - The invention provides a compound of Formula (I) | 12-17-2009 |
20110190489 | Novel Tricyclic Compounds - The invention provides a compound of Formula (Ia), (Ib), (Ic), (Id), (Ie), (If), (Ig), (Ih), (Ii), (Ij), (Ik), or (Il) as defined herein, pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions. | 08-04-2011 |
20120015963 | NOVEL PYRAZOLO[3,4-d]PYRIMIDINE COMPOUNDS - The present disclosure is directed to novel compounds of Formula (I) | 01-19-2012 |
20130216497 | NOVEL TRICYCLIC COMPOUNDS - The invention provides compounds of Formula (I) and Formula (II) | 08-22-2013 |
Patent application number | Description | Published |
20110039925 | CYCLOBUTYL SULFONES AS NOTCH SPARING GAMMA SECRETASE INHIBITORS - The invention encompasses a novel class of cyclobutyl sulfone derivatives which inhibit the processing of APP by the putative γ-secretase while sparing Notch signaling pathway, and thus are useful in the treatment or prevention of Alzheimer's disease without the development of Notch inhibition mediated gastrointestinal issues. Pharmaceutical compositions and methods of use are also included. | 02-17-2011 |
20110245205 | AMINOPYRIMIDINES AS SYK INHIBITORS - The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis. | 10-06-2011 |
20120022044 | TRIAZOLE DERIVATIVES FOR TREATMENT OF ALZHEIMER'S DISEASE - According to the invention there is provided a compound of formula I or a pharmaceutically acceptable salt or hydrate thereof; wherein the variables are as defined herein. The compounds selectively attenuate the production of Aβ42 and hence are useful in treatment of Alzheimer's disease and related conditions. | 01-26-2012 |
20120277192 | AMINOPYRIMIDINES AS SYK INHIBITORS - The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis. | 11-01-2012 |
20140243290 | Aminopyrimidines as SYK Inhibitors - The present invention provides novel pyrimidine amines of formula (I) which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD and rheumatoid arthritis. | 08-28-2014 |
Patent application number | Description | Published |
20090226395 | Pharmaceutical compositions of beta-lapachone and beta-lapachone analogs with improved tumor targeting potential - The present invention relates to polymer-modified quinone-containing and carbonyl-containing therapeutic agents, including polymer-modified β-lapachone compounds, and methods of treating cancer by administering the polymer-modified therapeutic agents to a subject. Polymer-modification of therapeutic agents, such as β-lapachone compounds, provides effective transport of polymer-modified therapeutic agents to tumor cells or tumor tissues by exploiting the EPR effect in tumor tissues. | 09-10-2009 |
20100221251 | Compositions and Methods for Treatment of Cancer - The present invention relates to pyrroloquinolinyl-pyrrole-2,5-dione compounds and pyrroloquinolinyl-pyrrolidine-2,5-dione compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrroloquinolinyl-pyrrole-2,5-dione compounds and pyrroloquinolinyl-pyrrolidine-2,5-dione compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or pyrroloquinolinyl-pyrrolidine-2,5-dione compound of the present invention. | 09-02-2010 |
20110280836 | COMPOSITIONS FOR BACTERIAL MEDIATED GENE SILENCING AND METHODS OF USING THE SAME - The invention features compositions and methods for delivering small interfering (siRNAs), e.g., shRNAs, to host cells using non-pathogenic strains of | 11-17-2011 |
20120009153 | COMPOSITIONS FOR BACTERIAL MEDIATED GENE SILENCING AND METHODS OF USING THE SAME - The invention features compositions and methods for delivering small interfering (siRNAs), e.g., shRNAs, to host cells using non-pathogenic strains of | 01-12-2012 |
20130150310 | Compositions and Methods for Treatment of Cancer - The present invention relates to pyrroloquinolinyl-pyrrolidine-2,5-dione compounds in combination with chemotherapeutic agents. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a pyrroloquinolinyl-pyrrole-2,5-dione compound or pyrroloquinolinyl-pyrrolidine-2,5-dione compound of the present invention and also administering a effective amount of a chemotherapeutic agent. | 06-13-2013 |
Patent application number | Description | Published |
20090156586 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS - This invention relates to compounds of the Formula (I): | 06-18-2009 |
20100120838 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS - This invention relates to compounds of the Formula (I): | 05-13-2010 |
20100145048 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS - This invention relates to compounds of the Formula (I): | 06-10-2010 |
20110288054 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS - This invention relates to compounds of the Formula (I) as described herein, or a pharmaceutically acceptable salt, solvate or ester thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof. | 11-24-2011 |
20110288077 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES - This invention relates to compounds of the Formula (I)-(IX):, as defined herein, or a pharmaceutically acceptable salt, solvate or ester thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-α combinations thereof. | 11-24-2011 |
20120010181 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS - This invention relates to compounds of the Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF—or combinations thereof. | 01-12-2012 |
20120015926 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS - This invention relates to compounds of the Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) or a pharmaceutically acceptable salt thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof. | 01-19-2012 |
Patent application number | Description | Published |
20100010655 | ASSEMBLY CONNECTION METHOD FOR ATTACHING VIRTUAL PARTS IN A COMPUTER AIDED DESIGN SOFTWARE ENVIRONMENT - A method and apparatus that allows the user of a computer aided design (CAD) system to connect three-dimensional parts to create a three-dimensional assembly using connections that completely define the attachment between the parts attached to each other by that connection. The user can simultaneously define the orientations of the parts and their behavior. “Behavior” includes whether parts are rigidly connected or allowed to move relative to one and other, and if allowed to move, the nature and limits on that movement. Within any movement allowed, the user may specify key discrete orientations known to be important to the function of the assembly, such as orientations that limit movement within the assembly. The connection method creates a smaller, more consistent representation of the underlying constraints of the assembly, improving the reliability, performance, and ease of use of a CAD system in which it is used. | 01-14-2010 |
20100060635 | ASSEMBLY-BASED PARAMETRIC MODELER - Presently disclosed is a process and system for assembly-based parametric modeling having a single design environment in which the parts, components, and assemblies thereof may be designed concurrently. In embodiments of the present invention, every assembly has a deterministic parametric history supporting both top-down and bottom-up assembly design methodologies. Top-down components may be built in place, reducing the user interaction required to define the attachment and movement characteristics of the assembly. Bottom-up components may be inserted into an assembly using a parametric Insert Component Feature. The process and system also provides the ability to parametrically define the shape of an assembly in multiple orientations that still regenerate deterministically. | 03-11-2010 |
Patent application number | Description | Published |
20080280982 | Glucagon Receptor Antagonists, Preparation and Therapeutic Uses - The present invention discloses novel compounds of Formula I, or pharmaceutically acceptable salts thereof, which have glucagon receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I as well as methods of using them to treat diabetic and other glucagon related metabolic disorders, and the like. | 11-13-2008 |
20080300308 | Glucagon Receptor Antagonists, Preparation and Therapeutic Uses - The present invention discloses novel compounds of Formula I, or pharmaceutically acceptable salts thereof, which have glucagon receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I as well as methods of using them to treat diabetic and other glucagon related metabolic disorders, and the like. | 12-04-2008 |
20090156655 | GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES - The present invention discloses novel compounds of Formula (I), or pharmaceutically acceptable salts thereof, which have glucagon receptor antagonist or inverse agonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of using them to treat diabetic and other glucagon related metabolic disorders, and the like. | 06-18-2009 |
Patent application number | Description | Published |
20110285389 | METHOD AND APPARATUS FOR SENSING A MAGNETIC FIELD - A magnetic screening system uses directional gradiometers with high resolution and accuracy to measure magnetic field signatures of target objects (e.g., gun, knife, cell phone, keys) in a volume of interest. The measured signatures can be compared to signatures of known objects stored in a local database. Various mathematical processes may be used to identify or classify target object signatures. In a network of magnetic screening systems, the magnetic screening systems can transmit signatures to a central signature database, and a management computer can share the central signature database with all of the magnetic screening systems on the network. The magnetic screening system can operate in multiple modes, such as a tracking mode, measurement mode, and self-test mode. Through use of unique processes and designs, the magnetic screening system can achieve a high rate of processing persons for target objects. | 11-24-2011 |
20110285392 | METHOD AND APPARATUS FOR OPERATING GRADIOMETERS IN MULTIPLE MODES - A magnetic screening system uses directional gradiometers with high resolution and accuracy to measure magnetic field signatures of target objects (e.g., gun, knife, cell phone, keys) in a volume of interest. The measured signatures can be compared to signatures of known objects stored in a local database. Various mathematical processes may be used to identify or classify target object signatures. In a network of magnetic screening systems, the magnetic screening systems can transmit signatures to a central signature database, and a management computer can share the central signature database with all of the magnetic screening systems on the network. The magnetic screening system can operate in multiple modes, such as a tracking mode, measurement mode, and self-test mode. Through use of unique processes and designs, the magnetic screening system can achieve a high rate of processing persons for target objects. | 11-24-2011 |
Patent application number | Description | Published |
20100310846 | CEMENTITIOUS FOAMS AND FOAM SLURRIES - Lightweight cementitious foams of the invention have excellent dynamic and dimensional stability due to use of foaming system comprising polycarboxylate surfactant foam generating agent, foam stabilizer (e.g., PVOH), and shrinkage reducing admixture to inhibit plastic shrinkage and micro-cracking of cement. The foaming system can be used in conventional cement mortars or concretes as well as with exemplary cementitious slurry systems of the invention, which include an expansive agent, a cross-linking agent for the foam stabilizer. Microfibers can be used in the foam, slurry, or both, to prevent micro-cracking. Cementitious foams can be made without use of autoclave or lightweight aggregates to achieve enhanced compressive strength and thermal insulation properties that compare favorably with conventional foams and insulation materials at comparable densities. | 12-09-2010 |
20120322902 | CEMENTITIOUS FOAM COMPOSITIONS - Lightweight cementitious foams of the invention have excellent dynamic and dimensional stability due to use of foaming system comprising polycarboxylate surfactant foam generating agent, foam stabilizer (e.g., PVOH), and shrinkage reducing admixture to inhibit plastic shrinkage and micro-cracking of cement. The foaming system can be used in conventional cement mortars or concretes as well as with exemplary cementitious slurry systems of the invention, which include an expansive agent, a cross-linking agent for the foam stabilizer. Microfibers can be used in the foam, slurry, or both, to prevent micro-cracking. Cementitious foams can be made without use of autoclave or lightweight aggregates to achieve enhanced compressive strength and thermal insulation properties that compare favorably with conventional foams and insulation materials at comparable densities. | 12-20-2012 |
Patent application number | Description | Published |
20100323294 | PHOTOACID GENERATORS AND PHOTORESISTS COMPRISING SAME - This invention relates to new photoacid generator compounds and photoresist compositions that comprise such compounds. In particular, the invention relates to photoacid generator compounds that comprise a multi cyclic lactone moiety. | 12-23-2010 |
20110250537 | CHOLATE PHOTOACID GENERATORS AND PHOTORESISTS COMPRISING SAME - New photoacid generator compounds (“PAGs”) are provided that comprise a cholate moiety and photoresist compositions that comprise such PAG compounds. | 10-13-2011 |
20110250538 | PHOTOACID GENERATORS AND PHOTORESISTS COMPRISING SAME - New methods are provided for synthesis of photoacid generator compounds (“PAGs”), new photoacid generator compounds and photoresist compositions that comprise such PAG compounds. In a particular aspect, sulfonium-containing (S+) photoacid generators and methods of synthesis of sulfonium photoacid generators are provided. | 10-13-2011 |
20110269074 | NOVEL POLYMERS AND PHOTORESIST COMPOSITIONS - New polymers are provided comprising (i) one or more covalently linked photoacid generator moieties and (ii) one or more photoacid-labile groups, wherein the one or more photoacid generator moieties are a component of one or more of the photoacid-labile groups. Preferred polymers of the invention are suitable for use in photoresists imaged at short wavelengths such as sub-200 nm, particularly 193 nm. | 11-03-2011 |
20120122030 | COMPOSITIONS COMPRISING BASE-REACTIVE COMPONENT AND PROCESSES FOR PHOTOLITHOGRAPHY - New photoresist compositions are provided that are useful for immersion lithography. Preferred photoresist compositions of the invention comprise one or more materials that comprise one or more base reactive groups and (i) one or more polar groups distinct from the base reactive groups, and/or (ii) at least one of the base reactive groups is a non-perfluorinated base reactive group. Particularly preferred photoresists of the invention can exhibit reduced leaching of resist materials into an immersion fluid contacting the resist layer during immersion lithography processing. | 05-17-2012 |
20120129104 | LACTONE PHOTOACID GENERATORS AND RESINS AND PHOTORESISTS COMPRISING SAME - New lactone-containing photoacid generator compounds (“PAGs”) and photoresist compositions that comprise such PAG compounds are provided. These photoresist compositions are useful in the manufacture of electronic devices | 05-24-2012 |
20120129108 | BASE REACTIVE PHOTOACID GENERATORS AND PHOTORESISTS COMPRISING SAME - This invention relates to new photoacid generator compounds and photoresist compositions that comprise such compounds. In particular, the invention relates to photoacid generator compounds that comprise base-cleavable groups. | 05-24-2012 |
20120156595 | COMPOSITIONS COMPRISING SUGAR COMPONENT AND PROCESSES FOR PHOTOLITHOGRAPHY - New photoresist compositions are provided that are useful for immersion lithography. Preferred photoresist compositions of the invention comprise one or more materials that have sugar substitution. Particularly preferred photoresists of the invention can exhibit reduced leaching of resist materials into an immersion fluid contacting the resist layer during immersion lithography processing. | 06-21-2012 |
20120171626 | COMPOSITIONS COMPRISING BASE-REACTIVE COMPONENT AND PROCESSES FOR PHOTOLITHOGRAPHY - New photoresist compositions are provided that comprise one or more materials that have base-reactive groups and are particularly useful for dry lithography. Particularly preferred photoresists of the invention can exhibit reduced defects following development of a coating layer of the resist. | 07-05-2012 |
20120301823 | POLYMER COMPOSITION AND PHOTORESIST COMPRISING THE POLYMER - A copolymer comprises the polymerized product of a base-soluble monomer of formula (I): | 11-29-2012 |
20130084525 | PHOTOACID GENERATOR AND PHOTORESIST COMPRISING SAME - A photoacid generator compound has the formula (I): | 04-04-2013 |
20130137038 | PHOTORESIST COMPOSITION - A photoresist composition comprises an acid-sensitive polymer, and a cyclic sulfonium compound having the formula: | 05-30-2013 |
20130171429 | CYCLOALIPHATIC MONOMER, POLYMER COMPRISING THE SAME, AND PHOTORESIST COMPOSITION COMPRISING THE POLYMER - A monomer has the Formula I: | 07-04-2013 |
20130171549 | CYCLOALIPHATIC MONOMER, POLYMER COMPRISING THE SAME, AND PHOTORESIST COMPOSITION COMPRISING THE POLYMER - A monomer has the Formula I: | 07-04-2013 |
20130171567 | PHOTOACID GENERATOR AND PHOTORESIST COMPRISING SAME - A photoacid generator includes those of formula (I): | 07-04-2013 |
20130344438 | PHOTOACID GENERATOR, PHOTORESIST, COATED SUBSTRATE, AND METHOD OF FORMING AN ELECTRONIC DEVICE - A photoacid generator has the formula (I): | 12-26-2013 |
20130344439 | PHOTORESISTS COMPRISING AMIDE COMPONENT - New photoresist compositions are provided that comprise a component that comprises an amide group and multiple hydroxyl groups. Preferred photoresists of the invention may comprise a resin with photoacid-labile groups; a photoacid generator compound; and an amide component with multiple hydroxyl groups that can function to decrease undesired photogenerated-acid diffusion out of unexposed regions of a photoresist coating layer | 12-26-2013 |
20140120471 | PHOTOACID GENERATING COMPOUND AND PHOTORESIST COMPOSITION COMPRISING SAME, COATED ARTICLE COMPRISING THE PHOTORESIST AND METHOD OF MAKING AN ARTICLE - A compound having the formula (I): | 05-01-2014 |
20140186770 | DENDRITIC COMPOUNDS, PHOTORESIST COMPOSITIONS AND METHODS OF MAKING ELECTRONIC DEVICES - Dendritic compounds are provided. The dendritic compounds include an anionic dendron that has a focal point having an anionic group and a linking group, and a photoreactive cation. The dendritic compounds find particular use as photoacid generators. Also provided are photoresist compositions that include such a dendritic compound, as well as methods of forming electronic devices with the photoresist compositions. The dendritic compounds, photoresist compositions and methods find particular applicability in the manufacture of semiconductor devices. | 07-03-2014 |
20140377465 | NEUTRAL LAYER POLYMERS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME - Disclosed herein is a block copolymer comprising a first segment and a second segment that are covalently bonded to each other and that are chemically different from each other; where the first segment has a first surface free energy and where the second segment has a second surface free energy; and an additive copolymer; where the additive copolymer comprises a surface free energy reducing moiety where the surface free energy reducing moiety has a lower surface free energy than that of the first segment and the second segment; the additive copolymer further comprising one or more moieties having an affinity to the block copolymer; where the surface free energy reducing moiety is chemically different from the first segment and from the second segment; where the additive copolymer is not water miscible; and where the additive copolymer is not covalently bonded with the block copolymer. | 12-25-2014 |
20140377518 | ORIENTATION CONTROL LAYER POLYMERS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME - Disclosed herein is a method comprising disposing a first composition comprising a first block copolymer upon a substrate; where the first block copolymer comprises a first segment and a second segment that are covalently bonded to each other and that are chemically different from each other; where the first segment has a first surface free energy and where the second segment has a second surface free energy; and disposing a second composition comprising an second copolymer upon a free surface of the first block copolymer; where the second copolymer comprises a surface free energy reducing moiety; where the surface free energy reducing moiety has a lower surface free energy than the first surface free energy and the second surface free energy; the second copolymer further comprising one or more moieties having an affinity to the first block copolymer; where the surface free energy reducing moiety is chemically different from the first segment and from the second segment. | 12-25-2014 |
20140378592 | NEUTRAL LAYER POLYMERS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME - Disclosed herein is a block copolymer comprising a first segment and a second segment that are covalently bonded to each other and that are chemically different from each other; where the first segment has a first surface free energy and where the second segment has a second surface free energy; and an additive copolymer; where the additive copolymer comprises a surface free energy reducing moiety where the surface free energy reducing moiety has a lower surface free energy than that of the first segment and the second segment; the additive copolymer further comprising one or more moieties having an affinity to the block copolymer; where the surface free energy reducing moiety is chemically different from the first segment and from the second segment; where the additive copolymer is not water miscible; and where the additive copolymer is not covalently bonded with the block copolymer. | 12-25-2014 |
20150056558 | PHOTOACID GENERATOR AND PHOTORESIST COMPRISING SAME - A photoacid generator compound has the formula (I): | 02-26-2015 |
Patent application number | Description | Published |
20080209050 | Multiple sessions between a server and a browser - A method and apparatus for a server capable of supporting multiple sessions with a browser. First session information of a browser is detected. Second session information of the browser is detected. A first session is initiated with a first browser instance of the browser using the first session information. A second session is initiated with a second browser instance of the browser using the second session information. | 08-28-2008 |
20080209338 | Browser supporting multiple users - A method and apparatus for a browser supporting multiple user identifying states. A plurality of browser instances are initiated on a client. One of a plurality of user identifying states is selected for each of the plurality of browser instances. Each selected user identifying state is used in a distinct session between the browser and a server. | 08-28-2008 |
20080235385 | Selective use of anonymous proxies - A method and apparatus for selectively using an anonymous proxy. A user request for content is received. A determination is made as to whether the user request satisfies context criteria. When the user request satisfies the context criteria, the user request is forwarded to an anonymous proxy. When the user request does not satisfy the context criteria, the request is sent directly to a content provider. | 09-25-2008 |
20080235623 | Privacy enhanced browser - A method and apparatus for filtering user identifying information. A user request for content is received, the request including user identifying information. A determination is made as to whether the user request satisfies context criteria. If the user request satisfies the context criteria, the user identifying information is filtered out from the user request. The filtered request is then sent to a content provider. | 09-25-2008 |
20100057745 | VIRTUAL DATABASE SYSTEM - A method and apparatus for distributing a database implementation across multiple servers. In one embodiment, the method includes receiving information identifying an implementation of a database having a database schema, identifying the number of database servers to host the database implementation, and analyzing usage characteristics of the database schema. The method further includes distributing the database implementation over the identified number of database servers based on the analysis of the usage characteristics, and providing access to the database implementation for one or more applications, the applications being unaware of the database servers hosting the database implementation. | 03-04-2010 |
20120246338 | SELECTIVE USE OF ANONYMOUS PROXIES - A method and computer system for selectively using an anonymous proxy. A user request for content is received. A determination is made as to whether the user request satisfies context criteria. When the user request satisfies the context criteria, the user request is forwarded to an anonymous proxy. When the user request does not satisfy the context criteria, the request is sent directly to a content provider. | 09-27-2012 |
Patent application number | Description | Published |
20090214222 | SYSTEM AND METHOD FOR PROTECTING AN EXTENDED PASSIVE OPTICAL NETWORK - Extender apparatus for an optical network includes first and second extender units having an network-facing port for connection to a backhaul fiber and a subscriber-facing port for connection to a feeder fiber. Each extender unit includes a gain assembly and is operable selectively either in an enabled state, in which the gain assembly amplifies a signal received at either port of the extender unit and couples it to the other port of the extender unit, or in a disabled state, in which the gain assembly blocks coupling of a signal from either port of the extender unit to the other port of the extender unit. A failover unit is operable when the first extender unit is in the enabled state and the second extender unit is in the disabled state to detect occurrence of at least one fault condition in the first extender unit. The failover unit is responsive to the fault condition in the first extender unit to switch the first extender unit to the disabled state and the second extender unit to the enabled state. | 08-27-2009 |
20120321309 | OPTICAL ARCHITECTURE AND CHANNEL PLAN EMPLOYING MULTI-FIBER CONFIGURATIONS FOR DATA CENTER NETWORK SWITCHING - Data center network architectures, systems, and methods that can reduce the cost and complexity of data center networks. Such data center network architectures, systems, and methods employ physical optical ring network and multi-dimensional network topologies and optical nodes to efficiently allocate bandwidth within the data center networks, while reducing the physical interconnectivity requirements of the data center networks. The respective optical nodes can be configured to provide various switching topologies, including, but not limited to, chordal ring switching topologies and multi-dimensional chordal ring switching topologies. | 12-20-2012 |
20120321310 | OPTICAL JUNCTION NODES FOR USE IN DATA CENTER NETWORKS - Data center network architectures, systems, and methods that can reduce the cost and complexity of data center networks. Such data center network architectures, systems, and methods employ physical optical ring network topologies, optical nodes, and optical junction nodes to efficiently allocate bandwidth within the data center networks, while reducing the overall physical interconnectivity requirements of the data center networks. | 12-20-2012 |
20140270762 | SYSTEM AND METHOD FOR DATA CENTER OPTICAL CONNECTION - A connectivity device permits simplified connections for realizing complex networking topologies using lower cost components. The device can be optically passive, or can have an active aspect to control switching to realize additional topology related features. The device permits cabling to be simplified while reducing cost to permit implementations of complex networking topologies to be realized faster and with greater reliability. The device aids in scaling out a network implementation and can provide connectivity for an arbitrary number of nodes with efficient capacity usage. | 09-18-2014 |
20150078746 | NETWORK NODE CONNECTION CONFIGURATION - A system and method for connectivity configuration of a network node permits an optical signal to be passed through the node and shifted from a first connector position to a second connector position that is offset from the first connector position. The shifted optical signal permits a number of distant nodes in the network to be reached with a direct optical connection, which can be configured to be bidirectional. The disclosed connectivity configuration reduces the cabling requirements for the network and simplifies the interconnections. | 03-19-2015 |
Patent application number | Description | Published |
20110217220 | Metal Oxide Compositions for Sequestering Carbon Dioxide and Methods of Making and Using the Same - The present invention is directed to methods of sequestering carbon dioxide using metal oxide compositions, methods of making the metal oxide compositions, and articles comprising the metal oxide compositions. | 09-08-2011 |
20110226697 | Functional Nanofibers and Methods of Making and Using the Same - The present invention is directed to functional nanofibers, methods of making the functional nanofibers, and products such as filters and membranes comprising mats of the functional nanofibers. | 09-22-2011 |
20110229750 | Polyolefin Fibers for Use as Battery Separators and Methods of Making and Using the Same - The present invention is directed to battery separators comprising layers of non-woven, melt-blown polyolefin fibers, and methods of making and using the same. | 09-22-2011 |
20140270599 | MICROSTRUCTURE CONNECTING MECHANISM AND PLASTIC STORAGE BAG WITH MICROSTRUCTURE CLOSURE MECHANISM - A connection mechanism including a plurality of microstructure features. The connection mechanism includes a first strip, with a plurality of protrusions extending from the first strip, and a second strip, with a plurality of protrusions extending from the second strip. The protrusions define grooves between adjacent protrusions. A pressure sensitive adhesive is provided in at least some of the grooves. When the first and second strips are brought together, the protrusions from one strip are received in the grooves of the other, and some of the protrusions contact the pressure sensitive adhesive, thereby connecting the first and second strips. The connection mechanism can be used as a closure mechanism for a plastic storage bag. | 09-18-2014 |
20140373853 | MOUTHGUARD - The present disclosure relates to a dental form comprising at least one first composition and at least one second composition, wherein the at least one first composition and the at least one second composition react when mixed to form a third composition. Also disclosed herein are mouthguards and kits comprising dental forms. | 12-25-2014 |
Patent application number | Description | Published |
20090208564 | Compositions of asymmetric interfering RNA and uses thereof - The present invention provides asymmetrical duplex RNA molecules that are capable of effecting sequence-specific gene silencing. The RNA molecule comprises a first strand and a second strand. The first strand is longer than the second strand. The RNA molecule comprises a double-stranded region formed by the first strand and the second strand, and two ends independently selected from the group consisting of 5′-overhang, 3′-overhang, and blunt end. The RNA molecules of the present invention can be used as research tools and/or therapeutics. | 08-20-2009 |
20100285006 | Compositions of Kinase Inhibitors and Their Use for Treatment of Cancer and Other Diseases Related to Kinases - The present invention relates to novel thiazole-substituted indolin-2-ones as inhibitors of CSCPK and related kinases; to methods of inhibiting cancer stem cells by using a kinase inhibitor; to pharmaceutical compositions containing such compounds; and to methods of using such compounds in the treatment of a protein kinase related disorder in a mammal; and to processes of making such compounds and intermediates thereof. | 11-11-2010 |
20100310503 | NOVEL COMPOSITIONS AND METHODS FOR CANCER TREATMENT - The present invention relates to the composition and methods of use of Stat3 pathway inhibitors or cancer stem cell inhibitors in combination treatment of cancer. | 12-09-2010 |
20120252763 | NOVEL GROUP OF STAT3 PATHWAY INHIBITORS AND CANCER STEM CELL PATHWAY INHIBITORS - The present invention relates to the use of a novel class of cancer stem cell pathway (CSCP) inhibitors; to methods of using such compounds to treat refractory, recurrent, or metastatic cancers; to methods of selective killing cancer cells by using such compounds with specific administration regimen; to methods of targeting cancer stem cells by inhibiting Stat3 pathway; to methods of using novel compounds in the treatment of conditions or disorders in a mammal related to aberrant Stat3 pathway activity; and to processes for preparing such compounds and intermediates thereof, and to the pharmaceutical composition of relevant compounds, and to the specific methods of administration of these compounds. | 10-04-2012 |
20120321622 | Compositions of Kinase Inhibitors and Their Use for Treatment of Cancer and Other Diseases Related to Kinases - The present invention relates to novel thiazole-substituted indolin-2-ones as inhibitors of CSCPK and related kinases; to methods of inhibiting cancer stem cells by using a kinase inhibitor; to pharmaceutical compositions containing such compounds; and to methods of using such compounds in the treatment of a protein kinase related disorder in a mammal; and to processes of making such compounds and intermediates thereof. | 12-20-2012 |
20130028944 | NOVEL METHODS FOR TARGETING CANCER STEM CELLS - The invention provides naphthofuran compounds, polymorphs of naphthofuran compounds, naphthofuran compounds in particle form, purified compositions that contain one or more naphthofuran compounds, purified compositions that contain one or more naphthofuran compounds in particle form, methods of producing these naphthofuran compounds, polymorphs, purified compositions and/or particle forms, and methods of using these naphthofuran compounds, polymorphs, purified compositions and/or particle forms to treat subjects in need thereof. | 01-31-2013 |
20130034591 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TARGETING CANCER STEM CELLS - The invention provides naphthofuran compounds, polymorphs of naphthofuran compounds, naphthofuran compounds in particle form, purified compositions that contain one or more naphthofuran compounds, purified compositions that contain one or more naphthofuran compounds in particle form, methods of producing these naphthofuran compounds, polymorphs, purified compositions and/or particle forms, and methods of using these naphthofuran compounds, polymorphs, purified compositions and/or particle forms to treat subjects in need thereof. | 02-07-2013 |
Patent application number | Description | Published |
20120010854 | Quantum Efficiency Measurement System and Method of Use - A system for measuring a characteristic of a solar cell is disclosed and includes a light source irradiating an optical signal having a spectral range from about 100 nm to about 3000 nm, a wavelength selector configured to selectively narrow the spectral range of the optical signal, a beam splitter, a reference detector in optical communication with the beam splitter and configured to measure a characteristic of the optical signal, a specimen irradiated with the optical signal, a reflectance detector in optical communication with the specimen via the beam splitter and configured to measure an optical characteristic of the optical signal reflected by the specimen, a multiplexer in communication with at least one of the reference detector, specimen, and reflectance detector, and a processor in communication with at least one of the reference detector, specimen, and reflectance detector via the multiplexer and configured to calculate at least one characteristic of the specimen. | 01-12-2012 |
20140252242 | SYSTEM AND METHOD FOR QUANTUM EFFICIENCY MEASUREMENT EMPLOYING DIFFUSIVE DEVICE - A system for measuring a characteristic of a solar cell is disclosed and includes a light source irradiating an optical signal having a spectral range from about 100 nm to about 3000 nm, a wavelength selector configured to selectively narrow the spectral range of the optical signal, a beam splitter, a reference detector in optical communication with the beam splitter and configured to measure a characteristic of the optical signal, a specimen irradiated with the optical signal, a reflectance detector in optical communication with the specimen via the beam splitter and configured to measure an optical characteristic of the optical signal reflected by the specimen, a multiplexer in communication with at least one of the reference detector, specimen, and reflectance detector, and a processor in communication with at least one of the reference detector, specimen, and reflectance detector via the multiplexer and configured to calculate at least one characteristic of the specimen. | 09-11-2014 |