Philip W.
Philip W. Garrett-Engele, Needham, MA US
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20110111976 | MICRORNA BIOMARKERS OF TISSUE INJURY - One aspect of the invention generally relates to use of tissue enriched miRNAs as biomarker to estimate tissue damage in a fluid sample. In a second aspect, methods are provided for monitoring a subject who is exposed or might have been exposed to an agent that has a risk of causing tissue injury. In a third aspect, methods are provided for identifying an agent as having a risk of causing tissue injury to a vertebrate subject. In a fourth aspect, kits are provided for practicing the methods of above-listed aspects. The contents of this ABSTRACT are not intended to in anyway limit the scope of the inventions claimed herein. | 05-12-2011 |
Philip W. Kantoff, Needham, MA US
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20130095481 | METHODS FOR PREDICTING LIKELIHOOD OF RESPONDING TO TREATMENT - The disclosure provides materials and methods related to using biomarkers for prediction of duration of response to prostate cancer treatment and for treating prostate cancer. | 04-18-2013 |
Philip W. Kantoff, Brookline, MA US
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20120121618 | Predicting And Treating Prostate Cancer - The disclosure features methods and compositions for determining whether a male subject has, or is at an increased risk of developing, an aggressive form of prostate cancer. The disclosure also features methods for adjusting a treatment regimen (e.g., discontinuing a therapy comprising an antioxidant) or administering a therapy that does not contain an antioxidant for a male subject in view of one or both of an MnSOD2 genotype status and an elevated level of an antioxidant in a biological sample obtained from the male subject. Also featured are methods for reducing superoxide levels in a subject based on one or both of an MnSOD2 genotype status and an elevated level of an antioxidant in a biological sample obtained from the male subject. | 05-17-2012 |
Philip W. Kithil, Santa Fe, NM US
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20110067641 | Methods and Apparatus For Increasing Upper-Level Fish Populations - A method and apparatus for pumping deeper water from a large body of water to an upper portion thereof using wave energy, thereby increasing nutrients at said upper portion and thus the fish populations thereof. | 03-24-2011 |
Philip W. Kithil, Sante Fe, NM US
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20150292471 | Hydraulic Pressure Generating System - A water pressurization system, comprising a substantially vertical assembly, the assembly comprising non-rigid connectors during shipment and storage, with the connectors assuming a semi-rigid form when in operation. | 10-15-2015 |
Philip W. Landfield, Lexington, KY US
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20130123188 | METHODS FOR DIAGNOSING AND TREATING ALZHEIMER'S DISEASE (AD) USING THE MOLECULES THAT STABILIZE INTRACELLULAR CALCIUM (Ca2+) - The subject technology relates, in part, to a method of treating Alzheimer's Disease (AD), early-stage AD, elevated risk of AD, mild cognitive impairment (MCI), or other forms of age-related cognitive decline in a subject in need thereof by administering to the subject a molecule that promotes calcium-release stabilization in ryanodine receptors (RyRs) and/or inosital triphosphate receptors (InsP3Rs) in brain cells. Diagnostic methods using calcium-release stabilizing immunophilins, junctophilins or calmodulin are also disclosed. | 05-16-2013 |
Philip W. Long, Castro Valley, CA US
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20160073704 | UNWEIGHTING GARMENTS FOR SIMULTANEOUS USE WITH UNWEIGHTING AND FALL SAFETY SYSTEMS - An integrated unweighting garment includes one or more reinforcement straps to couple the garment to a fall safety system. An unweighting garment includes an article of clothing having two leg portions configured to fit around legs of a user, a buttocks portion configured to fit around the user's buttocks, and a waist portion configured to fit proximate to hips of the user. One or more force distribution loop sections or reinforcement straps provided are attached along both leg portions or the buttocks portion or other portion of the garment or shoulder strap. An unweighting garment may include one or more of a sensor, a compression system or overhead suspension system connection points. | 03-17-2016 |
Philip W. Manijak, Corvallis, OR US
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20120023269 | PRESENTING ALERT NOTIFICATIONS - A method for presenting alert notifications includes identifying an alert condition for one of a master device, a slave device, and a production device. Operational states of the slave device and the master device are determined. For each of the slave device and the master device, upon a determination that the given device is in an idle state, that device is caused to display a notification corresponding to the identified alert condition. | 01-26-2012 |
Philip W. Pagliara, Tucson, AZ US
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20110029160 | METHODS AND APPARATUS FOR A TANDEM DIVERT AND ATTITUDE CONTROL SYSTEM - An aeronautical vehicle includes at least one set of tandem divert thrusters incorporated into the body. Each set of tandem divert thrusters includes a first divert thruster and a second divert thruster, each configured to provide substantially equal thrust forces at substantially the same time and in substantially opposite directions such that the moment reference point lies between the first and second divert thrusters. | 02-03-2011 |
Philip W. Pantella, Calgary CA
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20080288226 | Integrated Resevoir optimization - A method of managing a fluid or gas reservoir is disclosed which assimilates diverse data having different acquisition time scales and spatial scales of coverage for iteratively producing a reservoir development plan that is used for optimizing an overall performance of a reservoir. The method includes: (a) generating an initial reservoir characterization, (b) from the initial reservoir characterization, generating an initial reservoir development plan, (c) when the reservoir development plan is generated, incrementally advancing and generating a capital spending program, (d) when the capital spending program is generated, monitoring a performance of the reservoir by acquiring high rate monitor data-from a first set of data measurements taken in the reservoir and using the high rate monitor data to perform well-regional and field-reservoir evaluations, (e) further monitoring the performance of the reservoir by acquiring low rate monitor data from a second set of data measurements taken in the reservoir, (f) assimilating together the high rate monitor data and the low rate monitor data, (g) from the high rate monitor data and the low rate monitor data, determining when it is necessary to update the initial reservoir development plan to produce a newly updated reservoir development plan, (h) when necessary, updating the initial reservoir development plan to produce the newly updated reservoir development plan, and (i) when the newly updated reservoir development plan is produced, repeating steps (c) through (h). A detailed disclosure is provided herein relating to the step (a) for generating the initial reservoir characterization and the step (b) for generating the initial reservoir development plan. | 11-20-2008 |
Philip W. Regli, Lake Forrest, CA US
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20100305764 | Method and apparatus for emergency remote control of irrigation - A method and apparatus for controlling application of water in an irrigation cycle controlled by a non-centralized irrigation controller by receiving a water management command including, but not limited to a fire-shut-off command, a fire-activation-command, a drought-management-command, a pressure-management-command and a run-off-management-command. Once the command is received, parameters in the command are used to control the application of water for irrigation purposes. | 12-02-2010 |
Philip W. Schneck, Iii, Washington, DC US
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20120221479 | Web site, system and method for publishing authenticated reviews - The present invention provides a system and method for authenticating and publishing reviews of service providers. In particular, a third-party website receives information from a reviewer pertaining to a prior purchase and receipt of services from a service provider by the reviewer, and queries a database of the service provider to confirm that the information corresponds to a prior purchase in the database. If the information provided by the reviewer matches the service provider database, the review is accepted and posted online. If the information provided by the reviewer does not match the service provider database, the review is rejected and not published. | 08-30-2012 |
Philip W. Smith, Rockledge, FL US
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20080198237 | SYSTEM AND METHOD FOR ADAPTIVE PIXEL SEGMENTATION FROM IMAGE SEQUENCES - The image processing system includes an image processor performing adaptive pixel segmentation for a sequence of image frames collected during movement relative to a scene, with each image frame having a plurality of pixels. An image sensor collects the sequence of image frames while moving relative to the scene. The image processor may perform the adaptive pixel segmentation by generating a probability density function (PDF) for pixels based upon a plurality of past image frames from the sequence thereof, determining whether pixels in a new image frame from the sequence thereof are independently moving pixels or background pixels based upon comparing the new image frame to the at least one PDF, and updating the at least one PDF based upon the new image frame. | 08-21-2008 |
Philip W. Southern, Shinnston, WV US
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20080272207 | Water spray assembly - A water spray assembly especially adapted for control of dust suppression in mining machines has a manifold with one or a number of nozzles mounted thereon. The manifold provides communication between the nozzles and a manifold inlet, the manifold inlet being adapted to connect to a supply of water. The manifold with one half of a quick connect coupling cooperates with a nozzle block having a bore sized to receive at least a portion of the manifold and the other half of the quick connect coupling. The use of quick connect coupling half with the block allows easy removal and insertion of the manifold. | 11-06-2008 |
20100237682 | LOADING ARM WITH WEAR RESISTANT END, MINING EQUIPMENT USING THE ARM, AND METHOD OF USE - A loading arm assembly for directing material removed by a mining machining having a cutting head and a conveyor assembly includes one or more wear resistant plate assemblies at a terminal end of the loading arm. The wear resistant plate assembly includes a wear resistant plate arranged on a surface of arms of the loading arm assembly designed for directing the material to the conveyor. The assembly also has wear resistant inserts along a bottom surface of at least the arm end to protect the bottom surface of the arm from wear as well as the attachment of the wear resistant plate to the arm end. | 09-23-2010 |
20120019045 | WATER SPRAY SYSTEM FOR CONTINUOUS MINER AND METHOD OF USE - A continuous miner has a number of specially located water sprays to form a curtain of water spray across at least a portion of the miner width and behind the cutting assembly of the miner to suppress dust that would otherwise be directed to the operator of the miner and cause the miner operation to be out of compliance with safety regulations. | 01-26-2012 |
Philip W. Wyers, Centennial, CO US
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20100095717 | Locking device for trailer hitches and method therefor - A method and apparatus to secure the coupler section of a trailer provides a locking device that includes a lock housing having a hitch ball element to engage the recess in the coupler, a shackle member lockable to the housing and having a bridge section that spans the hitch ball element and, and a latch assembly to latch and unlatch the shackle member. The shackle member is shown to be U-shaped with legs that extend through and secure to the lock housing. The latch assembly provides a ratchet-type engagement to allow adjustable locking. A rotatable lock mechanism drives a cam based latch mechanism between a latch state and an unlatch state. | 04-22-2010 |
20100108448 | Locking wheel chock - A locking wheel device designed to prevent the unauthorized movement and or roll away of a wheeled vehicle or trailer by locking onto a wheel and having a configuration such that the device also serves to chock the wheel when in the locked on position. A locking wheel chock device which includes two similar matching arms with both a male and female tube attached to one end to allow for the telescopic engagement of said arms. The female tube having attached a lock assembly for locking said arms in a fixed position. Further, the female tube portion has attached to its lower edge, which is closest to the ground, means for contacting the ground in a binding fashion so as to prevent forward rolling movement of the wheel. | 05-06-2010 |