Snyder, MA
Brian D. Snyder, Westwood, MA US
Patent application number | Description | Published |
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20080221621 | TENSION FIXATION SYSTEM - The present invention provides an apparatus and method for fixation of a bone anchor to a structural member used for spinal fixation, whereby spinal deformity can be corrected and mechanical stability of the spine is provided so that load is carried fully or partially through the structural member. This invention provides fixation of a bone anchor to a structural member through tensile loading of a component of the fixation mechanism. This invention is widely adaptable to a variety of bone anchors and structural members. This invention allows reduction of spine deformity resulting from varied spinal disease through the fixation mechanism alone without the need for added reduction instrumentation systems. This invention equally provides a fixation mechanism for fixation of a bone anchor to the structural member of a spine fixation system in the absence of deformity. | 09-11-2008 |
Charles E. Snyder, Southwick, MA US
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20130186546 | MULTI-LAYER MATERIAL AND METHOD OF APPLICATION - A multi-layer material suitable for use as a covering for an article includes a polymeric cellular layer and nonwoven backing layer. The multi-layer material having a creasability angle of between about 20 and about 160 degrees. | 07-25-2013 |
Daniel Snyder, Somerville, MA US
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20120003260 | Solid-Phase and Solution-Phase Synthesis of Glycosylphosphatidylinositol Glycans - One aspect of the present invention relates to solution-phase approaches to GPI synthesis. Another aspect of the present invention relates to key building blocks, and syntheses thereof, useful for GPI assembly. Yet another aspect of the invention relates to an automated method for the synthesis of GPIs and fragments thereof. | 01-05-2012 |
Daniel A. Snyder, Cambridge, MA US
Patent application number | Description | Published |
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20080306127 | Compounds and methods for inhibiting the interaction of BCL proteins with binding partners - One aspect of the present invention relates to heterocyclic compounds that bind to bcl proteins and inhibit Bcl function. Another aspect of the present invention relates to compositions comprising a heterocyclic compound of the invention. The present invention provides methods for treating and modulating disorders associated with hyperproliferation, such as cancer. | 12-11-2008 |
Daniel A. Snyder, Somerville, MA US
Patent application number | Description | Published |
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20090099131 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE - The present invention provide compounds, and pharmaceutical compositions thereof, encompassed by the formulae (I), (II) or (III). | 04-16-2009 |
20100190791 | Compounds and Methods for Inhibiting the Interaction of BCL Proteins with Binding Partners - The present invention relates to heterocyclic compounds that bind to Bcl proteins and inhibit Bcl function, compositions comprising such compounds, and methods for treating and modulating disorders associated with hyperproliferation, such as cancer. | 07-29-2010 |
20110028478 | ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE - The present invention provides isoxazoline FAAH inhibitors of the formula (I): | 02-03-2011 |
20110028482 | ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE - The present invention provides isoxazoline FAAH inhibitors of the formula (I): | 02-03-2011 |
20110034437 | ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE - The present invention provides isoxazoline FAAH inhibitors of the formula (I): | 02-10-2011 |
20110160259 | Compounds and Methods for Inhibiting the Interaction of BCL Proteins with Binding Partners - One aspect of the present invention relates to heterocyclic compounds that bind to bcl proteins and inhibit Bcl function. Another aspect of the present invention relates to compositions comprising a heterocyclic compound of the invention. The present invention provides methods for treating and modulating disorders associated with hyperproliferation, such as cancer. | 06-30-2011 |
20110172186 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE - The present invention provides compounds, and pharmaceutically acceptable compositions thereof, encompassed by any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof. The present invention also provides methods for treating an FAAH mediated disease, disorder or condition by administering a therapeutically effective amount of a compound or composition comprising a compound of any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof, to a patient in need thereof. Additionally, the present invention provides methods for inhibiting FAAH by administering a therapeutically effective amount of a compound or composition comprising a compound of any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof, to a patient in need thereof. | 07-14-2011 |
20110213145 | Compounds and Methods for Inhibiting the Interaction of BCL Proteins with Binding Partners - The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer. | 09-01-2011 |
20110224171 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE - The present invention provide compounds, and pharmaceutical compositions thereof, encompassed by the formulae (I), (II) or (III). | 09-15-2011 |
20110230440 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE - The present invention provide compounds, and pharmaceutical compositions thereof, encompassed by the formulae (I), (II) or (III). | 09-22-2011 |
20110274655 | TETRAZOLONES AS INHIBITORS OF FATTY ACID SYNTHASE - Provided herein are tetrazolone FASN inhibitors of the formula (I): | 11-10-2011 |
20120122838 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein. | 05-17-2012 |
20130029982 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein. | 01-31-2013 |
20130029984 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein. | 01-31-2013 |
20130053362 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including P13 kinase activity, are described herein. | 02-28-2013 |
20130059819 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE - The present invention provide compounds, and pharmaceutical compositions thereof, encompassed by the formulae (I), (II) or (III). | 03-07-2013 |
20130131063 | Compounds and Methods for Inhibiting the Interaction of BCL Proteins with Binding Partners - The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer. | 05-23-2013 |
20130267521 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein. | 10-10-2013 |
20130345173 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE - Provided herein are compounds of formula (I) or pharmaceutically acceptable salts, solvates or prodrugs thereof, or mixtures thereof, wherein Z | 12-26-2013 |
20140079667 | TETRAZOLONES AS INHIBITORS OF FATTY ACID SYNTHASE - Provided herein are tetrazolone FASN inhibitors of the formula (I): | 03-20-2014 |
20140100214 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including P13 kinase activity, are described herein. | 04-10-2014 |
20140121183 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE - The present invention provide compounds, and pharmaceutical compositions thereof, encompassed by the formulae (I), (II) or (III). | 05-01-2014 |
20140235580 | INHIBITORS OF MONOACYLGLYCEROL LIPASE AND METHODS OF THEIR USE - Provided herein are compounds which mediate the activity of monoacyglycerol lipase (MAGL). Also provided are pharmaceutical compositions comprising a compound provided herein, and methods for treating, preventing and/or managing a MAGL mediated condition using a compound or pharmaceutical composition as provided herein. | 08-21-2014 |
20140288048 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including P13 kinase activity, are described herein. | 09-25-2014 |
20150031672 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein. | 01-29-2015 |
20150099738 | ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE - The present invention provides isoxazoline FAAH inhibitors of the formula (I): | 04-09-2015 |
20150105385 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein. | 04-16-2015 |
20150126506 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein. | 05-07-2015 |
20150246932 | HETEROCYCLIC COMPOUNDS AND USES THEREOF - Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein. | 09-03-2015 |
20150344503 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE, METHODS OF TREATMENT AND METHODS OF PREPARING SAME - The present invention provides compounds, and pharmaceutical compositions thereof, encompassed by the formulae (I), (II) or (III). | 12-03-2015 |
20150368278 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE - The present invention provides compounds, and pharmaceutically acceptable compositions thereof, encompassed by any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof. The present invention also provides methods for treating an FAAH mediated disease, disorder or condition by administering a therapeutically effective amount of a compound or composition comprising a compound of any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof, to a patient in need thereof. Additionally, the present invention provides methods for inhibiting FAAH by administering a therapeutically effective amount of a compound or composition comprising a compound of any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof, to a patient in need thereof. | 12-24-2015 |
Daniel A. Snyder, Someville, MA US
Patent application number | Description | Published |
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20120094957 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE - Provided herein are compounds of formula (I) or pharmaceutically acceptable salts, solvates or prodrugs thereof, or mixtures thereof, wherein Z | 04-19-2012 |
Eric L. Snyder, Brookline, MA US
Patent application number | Description | Published |
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20090098049 | Targeting transducible molecules to specific cell types - The disclosure provides fusion polypeptides and constructs useful in targeting molecules including diagnostics and therapeutics to a cell type of interest. The fusion constructs include a protein transduction domain, a ligand domain and a cargo domain. Also provided are methods of treating disease and disorders such as cell proliferative disorders. | 04-16-2009 |
Glenn Snyder, Sudbury, MA US
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20100280921 | SYSTEMS AND METHODS FOR IMPLEMENTING AND MANAGING VIRTUAL GIFT CARDS - According to one aspect, embodiments of the invention provide a method for administering a virtual gift card, the method comprising acts of receiving a request from a server of a retailer, providing, in response to the request, an interface to a terminal operated by a purchaser, the interface comprising fields for receiving a value and a recipient for the virtual gift card, receiving from the terminal, in response to input from the purchaser, the value and the recipient for the virtual gift card, generating a code for the virtual gift card, and sending a message to the recipient of the virtual gift card, the message including the code for the virtual gift card. | 11-04-2010 |
20130254063 | SYSTEMS AND METHODS FOR IMPLEMENTING AND MANAGING VIRTUAL GIFT CARDS - According to one aspect, embodiments of the invention provide a method for administering a virtual gift card, the method comprising acts of receiving a request from a server of a retailer, providing, in response to the request, an interface to a terminal operated by a purchaser, the interface comprising fields for receiving a value and a recipient for the virtual gift card, receiving from the terminal, in response to input from the purchaser, the value and the recipient for the virtual gift card, generating a code for the virtual gift card, and sending a message to the recipient of the virtual gift card, the message including the code for the virtual gift card. | 09-26-2013 |
20130254064 | SYSTEMS AND METHODS FOR IMPLEMENTING AND MANAGING VIRTUAL GIFT CARDS - According to one aspect, embodiments of the invention provide a method for administering a virtual gift card, the method comprising acts of receiving a request from a server of a retailer, providing, in response to the request, an interface to a terminal operated by a purchaser, the interface comprising fields for receiving a value and a recipient for the virtual gift card, receiving from the terminal, in response to input from the purchaser, the value and the recipient for the virtual gift card, generating a code for the virtual gift card, and sending a message to the recipient of the virtual gift card, the message including the code for the virtual gift card. | 09-26-2013 |
Glenn A. Snyder, Sudbury, MA US
Patent application number | Description | Published |
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20100299194 | SYSTEMS AND METHODS FOR IMPLEMENTING AND MANAGING GIFT CARDS - An offer management system is provided that evaluates conditions in relation to a gift card and triggers an action. In another example, the offer management system may be capable of evaluating attributes of a transaction using a gift card and may be capable of triggering an action. A trigger may be defined using one or more rules. For example, an administrator for a retailer may configure an offer rule in an interface of the offer management system. These rules may be evaluated in real-time, and offers made responsive to those evaluations. For example, offers may be made to a gift card recipient such as a discount on the total purchase, a dynamic addition of value to a gift card, issuance of a new gift card, or other offer. These offers may be used by a retailer to foster certain behaviors relating to gift cards. | 11-25-2010 |
20150294302 | COMPUTER SERVER SYSTEMS AND METHODS FOR DEFINING TRIGGER-BASED RULE SETS FOR EVALUATING ELECTRONIC-BASED INTERACTIONS BY A USER - An offer management system is provided that evaluates conditions in relation to a gift card and triggers an action. In another example, the offer management system may be capable of evaluating attributes of a transaction using a gift card and may be capable of triggering an action. A trigger may be defined using one or more rules. For example, an administrator for a retailer may configure an offer rule in an interface of the offer management system. These rules may be evaluated in real-time, and offers made responsive to those evaluations. For example, offers may be made to a gift card recipient such as a discount on the total purchase, a dynamic addition of value to a gift card, issuance of a new gift card, or other offer. These offers may be used by a retailer to foster certain behaviors relating to gift cards. | 10-15-2015 |
James S. Snyder, Suffield, MA US
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20120244282 | VAPOR DEPOSITION SOURCE - A vapor deposition source for vaporizing a material has a body forming an interior chamber, at least one crucible in the interior chamber, and a divider that divides the interior chamber into a transport channel and a distribution channel. To deposit vapor on an underlying substrate, the deposition source also has a plurality of exit orifices formed in the body adjacent to the distribution channel. The divider has a set of divider apertures between the transport channel and the distribution channel. This divider aperture is positioned generally symmetrically within the interior chamber. | 09-27-2012 |
John K. Snyder, Harvard, MA US
Patent application number | Description | Published |
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20110003776 | TETRAHYDROPYRANONAPHTHYRIDINES DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND THERAPEUTIC TREATMENT THEREOF - This invention relates to tetrahydropyranonaphthyridines derivatives having formula (III) or IV: | 01-06-2011 |
20130065875 | SMALL MOLECULE INHIBITORS OF HEPATITIS C VIRUS - The invention provides derivatives and analogues of triazatetracyclo[7.7.0.0 | 03-14-2013 |
L. Michael Snyder, Framingham, MA US
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20090312952 | Early Diagnosis of Acute Coronary Syndrome - The invention relates to methods for the early diagnosis of Acute Coronary Syndrome. | 12-17-2009 |
Mark Snyder, Wellesley, MA US
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20160042456 | TECHNIQUES FOR AUTOMATED CALL CROSS TRADE IMBALANCE EXECUTION - Various embodiments are generally directed to techniques for automated call cross trade imbalance execution. Techniques described herein may provide an automated crossing solution for buy-side clients that limits position information to banks and individuals prior to setting a benchmark rate for foreign exchange. In some embodiments, clients may roll forward spot trades with a chosen counterparty bank, which is then sent to a centralized, automated, bank platform. Techniques described herein may offer a multi-bank platform solution that accepts trades, validates trades, performs credit checks, and executes trades in a manner that limits knowledge of position information prior to setting a benchmark rate. Further, proposed techniques include determining a trade imbalance and automatically executing the determined trade imbalance in a manner such that market impact is minimalized. In some embodiments, trade imbalances may be calculated on a bank-by-bank basis, thus allowing each bank to execute its own trade imbalance. Other embodiments are described. | 02-11-2016 |
Mark E. Snyder, Sudbury, MA US
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20110029651 | DYNAMIC SERVER CONSOLIDATION AND RATIONALIZATION MODELING TOOL - A method and system for providing efficient and flexible techniques for modeling technical and economic benefits of consolidating information technology (IT) systems, hardware, software, network, and other infrastructure are described. The system includes a data processing system configured to receive data from a user. The system also includes an input collection system communicatively coupled to the data processing system, with the input collection system designed to organize, convert, and sort the data to generate baseline server information. In addition, the system includes an optimization system communicatively coupled to the data processing system, with the optimization system designed to generate one or more server consolidation models based on the baseline server information. Further, based on the generated one or more server consolidation models, a recommendation can be generated. | 02-03-2011 |
Phillip W. Snyder, Cambridge, MA US
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20090318542 | OPHTHAMOLOGICAL DRUGS - The present invention relates generally to ophthamological drugs. More specifically, the invention relates to a method of modifying (derivatizing) ophthamological drugs so as to increase their penetration through the cornea. The invention also relates to drugs modified (derivatized) in accordance with the instant method and to the use of same in treating conditions associated with elevated intraocular pressure, particularly, glaucoma. | 12-24-2009 |
Robert J. Snyder, Westford, MA US
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20080316986 | Remote Antenna for Wireless Access Point - A center access point ( | 12-25-2008 |
Thomas E. Snyder, Wellesley Hills, MA US
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20090246745 | System and method for guiding next step adaptive behavior - The system and method of the present invention process clarified emotional response data in order to guide next step adaptive behavior. Emotional responses with predetermined clarified intensities are sorted. The best quality clarified intensity or intensities are then selected as the ‘heart of the matter’, which is then shown to a user to reveal how the user is most uniquely responding to a particular subject or issue. The user is then given guidance on how to respond to the particular subject or issue thereby guiding the user's behavior in response to such subject or issue. | 10-01-2009 |
Thomas M. Snyder, Cambrige, MA US
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20110190141 | Evolving New Molecular Function - Nature evolves biological molecules such as proteins through iterated rounds of diversification, selection, and amplification. The power of Nature and the flexibility of organic synthesis are combined in nucleic acid-templated synthesis. The present invention provides a variety of template architectures for performing nucleic acid-templated synthesis, methods for increasing the selectivity of nucleic acid-templated reactions, methods for performing stereoselective nucleic acid-templated reactions, methods of selecting for reaction products resulting from nucleic acid-templated synthesis, and methods of identifying new chemical reactions based on nucleic acid-templated synthesis. | 08-04-2011 |