Patent application number | Description | Published |
20100101807 | DOWNHOLE APPARATUS WITH PACKER CUP AND SLIP - A downhole apparatus and for use in a well bore and associated method are disclosed. The downhole apparatus includes a center mandrel. A slip means is disposed on the mandrel. The slip means can include teeth or the like for grippingly engaging the well bore when in a set position. A packer cup is also disposed on the mandrel. The packer cup is provided for sealing an annulus between the mandrel and the well bore. The packer cup is slidable relative to the mandrel, and can be controlled to slide along the mandrel in order to move the slip to the set position. Also disclosed is a downhole assembly that includes a downhole tool and a setting apparatus. The setting apparatus can be used for lowering the downhole apparatus to a desired setting depth and then releasing the downhole apparatus. | 04-29-2010 |
20110308820 | Downhole Apparatus with Packer Cup and Slip - A downhole apparatus and assembly for use in a well bore and associated method are disclosed. The downhole apparatus includes a mandrel, a first slip, and a second slip, both slips being disposed on the mandrel. The slips are configured to grippingly engaging the well bore when in a set position. A packer cup is also disposed on the mandrel. The packer cup is provided for sealing an annulus between the mandrel and the well bore. The packer cup is slidable relative to the mandrel, and can be controlled to slide along the mandrel in order to move the slip to the set position. The downhole assembly includes a downhole tool and a setting apparatus. The setting apparatus can be used to lower the downhole apparatus to a desired setting depth and then to release the downhole apparatus. | 12-22-2011 |
20120080202 | Downhole Apparatus with Packer Cup and Slip - A downhole apparatus and for use in a well bore and associated method are disclosed. The downhole apparatus includes a center mandrel. A slip means is disposed on the mandrel. The slip means can include teeth or the like for grippingly engaging the well bore when in a set position. A retractable packer cup is also disposed on the mandrel. The retractable packer cup is provided for sealing an annulus between the mandrel and the well bore. The retractable packer cup is slidable relative to the mandrel, and can be controlled to slide along the mandrel in order to move the slip to the set position. Also disclosed is a downhole assembly that includes a downhole tool and a setting apparatus. The setting apparatus can be used for lowering the downhole apparatus to a desired setting depth and then releasing the downhole apparatus. | 04-05-2012 |
20130220638 | Hydrostatic Setting Tool - A setting tool for use inside a well bore casing having an upper portion, a lower portion, and a wrap spring. The upper portion includes a mandrel coupled to a connecting line. The upper portion is configured to receive an input. The lower portion includes a first sleeve configured translate along an axis of the setting tool. The lower portion is selectively coupled to the upper portion. The wrap spring has a torsional preload and is coupled to the upper portion and the lower portion. The wrap spring is configured to selectively release the lower portion and upon reception of the input, such that the first sleeve is permitted to translate along the axis. | 08-29-2013 |
20150368995 | Hydrostatic Setting Tool - A setting tool for use inside a well bore casing having an upper portion, a lower portion, and a wrap spring. The upper portion includes a mandrel coupled to a connecting line. The upper portion is configured to receive an input. The lower portion includes a first sleeve configured translate along an axis of the setting tool. The lower portion is selectively coupled to the upper portion. The wrap spring has a torsional preload and is coupled to the upper portion and the lower portion. The wrap spring is configured to selectively release the lower portion and upon reception of the input, such that the first sleeve is permitted to translate along the axis. | 12-24-2015 |
Patent application number | Description | Published |
20130220638 | Hydrostatic Setting Tool - A setting tool for use inside a well bore casing having an upper portion, a lower portion, and a wrap spring. The upper portion includes a mandrel coupled to a connecting line. The upper portion is configured to receive an input. The lower portion includes a first sleeve configured translate along an axis of the setting tool. The lower portion is selectively coupled to the upper portion. The wrap spring has a torsional preload and is coupled to the upper portion and the lower portion. The wrap spring is configured to selectively release the lower portion and upon reception of the input, such that the first sleeve is permitted to translate along the axis. | 08-29-2013 |
20140190682 | Downhole Tool Apparatus with Slip Plate and Wedge - A downhole tool that is used to seal a well bore. The downhole tool has at least one of a nose cap coupled to a slip means for converting shear forces into compression forces, a pultrusion rod, and a butterfly ring. The pultrusion rod extends the full length of the center mandrel. The butterfly ring includes a plurality of wedges configured to remove the extrusion gap when the tool is expanded to prevent failure of a sealing member over increased well bore diameters. The downhole tool includes a pressure equalization port to equalize pressure between a first and a second fluid volume during removal of the tool from the well bore. | 07-10-2014 |
20150368995 | Hydrostatic Setting Tool - A setting tool for use inside a well bore casing having an upper portion, a lower portion, and a wrap spring. The upper portion includes a mandrel coupled to a connecting line. The upper portion is configured to receive an input. The lower portion includes a first sleeve configured translate along an axis of the setting tool. The lower portion is selectively coupled to the upper portion. The wrap spring has a torsional preload and is coupled to the upper portion and the lower portion. The wrap spring is configured to selectively release the lower portion and upon reception of the input, such that the first sleeve is permitted to translate along the axis. | 12-24-2015 |
Patent application number | Description | Published |
20110274490 | METHOD AND COMPOSITION FOR ROAD CONSTRUCTION AND SURFACING - Methods and compositions for improving the strength and longevity of secondary roadways through environmentally sound practices are disclosed herein. A composition for road sealing includes an aqueous emulsion of acrylic and vinyl acetate polymer, water, and a resin-modified emulsion, wherein the resin-modified emulsion includes a mixture of pitch and rosin, an emulsifying agent, and water. | 11-10-2011 |
20120129983 | METHOD AND COMPOSITION FOR ROAD CONSTRUCTION AND SURFACING - Methods and compositions for improving the strength and longevity of secondary roadways through environmentally sound practices are disclosed herein. A composition for road sealing includes an aqueous emulsion of acrylic and vinyl acetate polymer, water, and a resin-modified emulsion, wherein the resin-modified emulsion includes a mixture of pitch and rosin, an emulsifying agent, and water. | 05-24-2012 |
20120129984 | METHOD AND COMPOSITION FOR ROAD CONSTRUCTION AND SURFACING - Methods and compositions for improving the strength and longevity of secondary roadways through environmentally sound practices are disclosed herein. A composition for road sealing includes an aqueous emulsion of acrylic and vinyl acetate polymer, water, and a resin-modified emulsion, wherein the resin-modified emulsion includes a mixture of pitch and rosin, an emulsifying agent, and water. | 05-24-2012 |
20130197128 | METHOD AND COMPOSITION FOR ROAD CONSTRUCTION AND SURFACING - Methods and compositions for improving the strength and longevity of secondary roadways through environmentally sound practices are disclosed herein. A composition for road sealing includes an aqueous emulsion of acrylic and vinyl acetate polymer, water, and a resin-modified emulsion, wherein the resin-modified emulsion includes a mixture of pitch and rosin, an emulsifying agent, and water. | 08-01-2013 |
20140186117 | METHOD AND COMPOSITION FOR ROAD CONSTRUCTION AND SURFACING - Methods and compositions for improving the strength and longevity of secondary roadways through environmentally sound practices are disclosed herein. A composition for road sealing includes acrylic and vinyl acetate powdered polymer mixed with native soil. | 07-03-2014 |
Patent application number | Description | Published |
20080222713 | SYSTEM AND METHOD FOR AUTHENICATION TO AN APPLICATION - Authenticating a first user in a protected network to an application in a DMZ network shared simultaneously with a second user in an unprotected network. The first user supplies a userID and a password to a first server within the protected network for authentication for the application. The first server checks authentication of the first user based on the userID and password. If the first user is authentic, the first server forwards to the application an authentication key for the first user and a selection by the first user pertaining to the application. The application checks authentication of the key, and if authentic, complies with the selection by the first user. The second user supplies another userID and another password to the application. If the other userID and other password are authentic, the application complies with a selection made by the second user pertaining to the application. | 09-11-2008 |
20080282359 | SYSTEM FOR CONTROLLING WRITE ACCESS TO AN LDAP DIRECTORY - A method is provided to control access to a software application and, more particularly, to control access to a first software application using a second trusted application. The method comprises extracting data from a decrypted client request and determining a request type from the extracted data. The method further comprises ascertaining an entry type value from at least one of the extracted data and an entry and creating at least one string by prepending the entry type value to one or more attributes associated with the entry. Additionally, the method includes comparing the at least one string to one or more record entries to determine whether a client has permission to perform the request type. | 11-13-2008 |
20100146517 | SYSTEM AND METHOD FOR A RATE CONTROL TECHNIQUE FOR A LIGHTWEIGHT DIRECTORY ACCESS PROTOCOL OVER MQSERIES (LOM) SERVER - A system and method for controlling rates for a Lightweight Directory Access Protocol (LDAP) over MQSeries (LoM) server. The system comprises a health metrics engine configured to calculate an actual delay value, at least one LoM server configured to asynchronously obtain the actual delay value from the health metrics engine and place the delay value between one or more requests, and a LDAP master configured to accept the one or more requests and send information in the one or more requests to a LDAP replica. | 06-10-2010 |
20120136833 | DISASTER RECOVERY UTILIZING COLLAPSIBLE VIRTUALIZED CAPACITY - Aspects of the present invention provide a solution for implementing disaster recovery for an application. A subscription backup site for the application is selected from among a plurality of sites. The site that is selected will have a virtual space that is able to accommodate the workload requirements for the application. The application is deflated on the site in such as way as to operate in a dormant state. In the dormant state, the application has a small fraction of its required resources allocated to it. Thereafter, when disaster recovery is needed, the application can be inflated on the subscription backup site by allocating resources to enable the application to execute on the subscription backup site. | 05-31-2012 |
20120331171 | System and Method for a Rate Control Technique for a Lightweight Directory Access Protocol Over MQSeries (LOM) Server - A system and method for controlling rates for a Lightweight Directory Access Protocol (LDAP) over MQSeries (LoM) server. The system includes a health metrics engine that calculates an actual delay value, a LoM server that asynchronously obtains the actual delay value from the health metrics engine and place the delay value between one or more requests, and a LDAP master that accepts the one or more requests and send information in the one or more requests to a LDAP replica. | 12-27-2012 |
20130326035 | CENTRALIZED ENTERPRISE LEVEL INFRASTRUCTURE MANAGEMENT - An approach is provided for managing an enterprise computer system. Management functions are coordinated from a central control point. The central control point can direct one or more agents to be deployed to establish a connection to an element in its unmodified form within the enterprise system. Agents can be directed by the central control point to establish this connection in accordance with a profile that corresponds to the element. Once the connection has been established, the agent can perform a management task with respect to the element. | 12-05-2013 |
20140006614 | ON-DEMAND GLOBAL SERVER LOAD BALANCING SYSTEM AND METHOD OF USE | 01-02-2014 |
20140122926 | SIMULATION ENGINE FOR USE IN DISASTER RECOVERY VIRTUALIZATION - An approach is provided for determining disaster recovery capacity. A simulation hypervisor receives streaming metric data, which represents the current production workload of a primary site, from the primary site. The metric data is combined with production data of the backup site by the simulation hypervisor to simulate a recovery event. Using data from the simulating, disaster recovery planning can be performed. | 05-01-2014 |
20140136681 | Enterprise Application Session Control and Monitoring in a Large Distributed Environment - Mechanisms are provided for performing centralized monitoring of application sessions across a distributed computing environment comprising a plurality of application servers. A request to perform an application session monitoring operation to monitor at least one of input or output streams of application sessions associated with a specified user account identifier is received. A plurality of application instances upon which to perform the requested application session monitoring operation are identified. An application session monitoring request is transmitted to a plurality of session control clients associated with the application instances on a plurality of application servers of the distributed computing environment. The application session monitoring request causes each session control client to monitor at least one of an input or an output stream of application sessions of application instances that are associated with the specified user account identifier, and report results of the monitoring back to the data processing system. | 05-15-2014 |
20140137186 | Enterprise Application Session Control and Monitoring in a Large Distributed Environment - Mechanisms are provided for performing centralized control of application sessions across a distributed computing environment comprising a plurality of application servers. A request to perform an application session control operation to control the application sessions associated with a specified user account identifier across the plurality of application servers in the distributed computing environment is received. A plurality of application instances upon which to perform the requested application session control operation are identified. An application session control request is transmitted to a plurality of session control clients associated with the application instances on the plurality of application servers of the distributed computing environment. The application session control request causes each session control client to control a user's ability to use the application sessions of application instances, associated with the session control client, that are associated with the specified user account identifier, to access the associated application instances. | 05-15-2014 |
20140164817 | DISASTER RECOVER INTERNET PROTOCOL ADDRESS FAILOVER - An approach is provided for internet protocol (IP) address failover. An application on a primary site is assigned a private IP address. This private IP address is accessible within a local network. This private IP address is mapped to a public IP address, which is accessible to users outside the local network. The application is then replicated to a backup site with the same private IP address used to access it on the primary site. In case of a disaster recover event on the primary site, the replicated application can be accessed on the backup site by way of the public IP address. | 06-12-2014 |
20150142971 | System and Method for a Rate Control Technique for a Lightweight Directory Access Protocol Over MQSeries (LOM) Server - A system and method for controlling rates for a Lightweight Directory Access Protocol (LDAP) over MQSeries (LoM) server. The system includes a health metrics engine that calculates an actual delay value, a LoM server that asynchronously obtains the actual delay value from the health metrics engine and place the delay value between one or more requests, and a LDAP master that accepts the one or more requests and send information in the one or more requests to a LDAP replica. | 05-21-2015 |
20150244579 | DYNAMIC EXTENSIBLE APPLICATION SERVER MANAGEMENT - An administrative control interface is provided that controls deployed application server plugins that operate within an application-server plugin framework deployed at a group of application servers. The administrative control interface controls dynamic adjustment of runtime application server plugin configurations that perform request-level management and server-level management of the group of application servers. Request-level application server functionality and server-level application server functionality of at least one of the group of application servers is controlled using at least one of the deployed application server plugins as specified by application-server plugin commands received from the administrative control interface. | 08-27-2015 |
20150244585 | DYNAMIC EXTENSIBLE APPLICATION SERVER MANAGEMENT - An administrative control interface is provided that controls deployed application server plugins that operate within an application-server plugin framework deployed at a group of application servers. The administrative control interface controls dynamic adjustment of runtime application server plugin configurations that perform request-level management and server-level management of the group of application servers. Request-level application server functionality and server-level application server functionality of at least one of the group of application servers is controlled using at least one of the deployed application server plugins as specified by application-server plugin commands received from the administrative control interface. | 08-27-2015 |
20150261629 | SIMULATION ENGINE FOR USE IN DISASTER RECOVERY VIRTUALIZATION - An approach is provided for determining disaster recovery capacity. A simulation hypervisor receives streaming metric data, which represents the current production workload of a primary site, from the primary site. The metric data is combined with production data of the backup site by the simulation hypervisor to simulate a recovery event. Using data from the simulating, disaster recovery planning can be performed. | 09-17-2015 |
Patent application number | Description | Published |
20090163559 | Estrogen receptor modulators - The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a variety of conditions related to estrogen functioning including: bone loss, bone fractures, osteoporosis, metastatic bone disease, Paget's disease, periodontal disease, cartilage degeneration, endometriosis, uterine fibroid disease, hot flashes, increased levels of LDL cholesterol, cardiovascular disease, impairment of cognitive functioning, age-related mild cognitive impairment, cerebral degenerative disorders, restenosis, gynecomastia, vascular smooth muscle cell proliferation, obesity, incontinence, inflammation, inflammatory bowel disease, irritable bowel syndrome, sexual dysfunction, hypertension, retinal degeneration and cancer, in particular of the breast, uterus and prostate. | 06-25-2009 |
20090306202 | D-homoandrosta-17-yl carbamate derivatives as selective glucocorticoid receptor ligands - The present invention is directed to D-homoandrosta-17-yl-carbamate derivatives as selective glucocorticoid receptor ligands useful for treating a variety of autoimmune and inflammatory diseases or conditions. Pharmaceutical compositions and methods of use are also included. | 12-10-2009 |
20100113439 | Antifungal agents - Novel derivatives of enfumafungin are disclosed herein, along with their pharmaceutically acceptable salts, hydrates and prodrugs. Also disclosed are compositions comprising such compounds, methods of preparing such compounds and methods of using such compounds as antifungal agents and/or inhibitors of (1,3)-β-D-glucan synthase. The disclosed compounds, their pharmaceutically acceptable salts, hydrates and prodrugs, as well as compositions comprising such compounds, salts, hydrates and prodrugs, are useful for treating and/or preventing fungal infections and associated diseases and conditions. | 05-06-2010 |
20100168188 | Estrogen Receptor Modulators - The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a variety of conditions related to estrogen functioning including: bone loss, bone fractures, osteoporosis, metastatic bone disease, Paget's disease, periodontal disease, cartilage degeneration, endometriosis, uterine fibroid disease, hot flashes, increased levels of LDL cholesterol, cardiovascular disease, impairment of cognitive functioning, cerebral degenerative disorders, restenosis, gynecomastia, vascular smooth muscle cell proliferation, obesity, incontinence, inflammation, inflammatory bowel disease, sexual dysfunction, hypertension, retinal degeneration and cancer, in particular of the breast, uterus and prostate. | 07-01-2010 |
20110224228 | ANTIFUNGAL AGENTS - Novel derivatives of enfumafungin are disclosed herein, along with' their pharmaceutically acceptable salts, hydrates and prodrugs. Also disclosed are compositions comprising such compounds, methods of preparing such compounds and method of using such compounds as antifungal agents and/or inhibitors of (1,3)-β-D-glucan synthase. The disclosed compounds, their pharmaceutically acceptable salts, hydrates and prodrugs, as well as compositions comprising such compounds, salts, hydrates and prodrugs, are useful for treating and/or preventing fungal infections and associated diseases and conditions. | 09-15-2011 |
Patent application number | Description | Published |
20150064365 | METHODS OF FORMING FILMS - A method of forming a layer, the method including providing a feedstock, the feedstock including a first component and a second component; ionizing at least part of the feedstock thereby forming a plasma, wherein the plasma includes constituents selected from: the first component, derivatives of the first component, ions of the first component, ions of derivatives of the first component, the second component, derivatives of the second component, ions of the second component, ions of derivatives of the second component, or combinations thereof, and wherein the individual identities, individual ratios, total quantities, or any combination thereof of the first and second component in the feedstock can modulate the makeup of the plasma; forming a beam from the plasma; and forming a layer from the beam, wherein the layer includes at least some portion of at least the first or the second component. | 03-05-2015 |
Patent application number | Description | Published |
20130164453 | METHODS OF FORMING LAYERS - A method of forming a layer, the method including providing a substrate having at least one surface adapted for forming a layer thereon; directing a particle beam towards the surface of the substrate, the particle beam including particles, wherein the particle beam has an angle of incidence with respect to the substrate, and is configured so that the particles have implant energies that are not greater than about 100 eV; changing the angle of incidence of the particle beam, the implant energy of the particles, or a combination thereof; and directing the particle beam towards the surface of the substrate a subsequent time, wherein the particles of the particle beam form a layer on the substrate. | 06-27-2013 |
20130164454 | METHODS OF FORMING LAYERS - A method of forming a layer, the method including providing a substrate having at least one surface adapted for deposition thereon; and directing a particle beam towards the surface of the substrate, the particle beam including small molecule molecular species, wherein the small molecule molecular species break apart upon interaction with atoms at the substrate into atomic components, each of the atomic components having implant energies from about 20 eV to about 100 eV to form a layer. | 06-27-2013 |
Patent application number | Description | Published |
20100299404 | TECHNIQUE FOR PROVIDING PROGRAM GUIDE DATA THROUGH A COMMUNICATIONS NETWORK DELIVERING PROGRAMMING CONTENT - In order to efficiently utilize the limited transmission bandwidth of a communications network, e.g., a cable network, guide data for constructing an interactive program guide (IPG) is delivered to a set-top terminal using different methodologies. For example, the guide data associated with those programs which are likely of interest to a user is automatically provided piecemeal in a broadcast stream. The set-top terminal, along with other terminals, may retrieve from such a broadcast stream some or all of the guide data therein over time, which is cached in the terminal in anticipation of a user's invocation of an IPG. On the other hand, the guide data associated with those programs which are less likely of interest to a user is furnished upon request by the set-top terminal needing such guide data to realize an IPG desired by the user. In addition, guide data for each program may be divided into detail guide data providing details of the program (e.g., a synopsis of the program content), and grid guide data providing basic information about the program (e.g., title, channel and broadcast time). A first time window and a second time window may be defined such that the grid guide data associated with those programs broadcast within the first time window and the detail guide data associated with those programs broadcast within the second time window are automatically provided in the broadcast stream. The rest of the detail and grid guide data may be furnished upon request when needed. | 11-25-2010 |
20140298388 | TECHNIQUE FOR PROVIDING PROGRAM GUIDE DATA THROUGH A COMMUNICATIONS NETWORK DELIVERING PROGRAMMING CONTENT - In order to efficiently utilize the limited transmission bandwidth of a communications network, e.g., a cable network, guide data for constructing an interactive program guide (IPG) is delivered to a set-top terminal using different methodologies. For example, the guide data associated with those programs which are likely of interest to a user is automatically provided piecemeal in a broadcast stream. The set-top terminal, along with other terminals, may retrieve from such a broadcast stream some or all of the guide data therein over time, which is cached in the terminal in anticipation of a user's invocation of an IPG. On the other hand, the guide data associated with those programs which are less likely of interest to a user is furnished upon request by the set-top terminal needing such guide data to realize an IPG desired by the user. In addition, guide data for each program may be divided into detail guide data providing details of the program (e.g., a synopsis of the program content), and grid guide data providing basic information about the program (e.g., title, channel and broadcast time). A first time window and a second time window may be defined such that the grid guide data associated with those programs broadcast within the first time window and the detail guide data associated with those programs broadcast within the second time window are automatically provided in the broadcast stream. The rest of the detail and grid guide data may be furnished upon request when needed. | 10-02-2014 |
Patent application number | Description | Published |
20130046007 | SELECTIVE REDUCTION OF ALLELIC VARIANTS - Disclosed herein are antisense compounds and methods for selectively of reducing expression of an allelic variant of a gene containing a single nucleotide polymorphism (SNP). Such methods, compounds, and composition are useful to treat, prevent, or ameliorate diseases, including neurodegenerative, such as Huntington's Disease (HD). | 02-21-2013 |
20130046008 | SELECTIVE REDUCTION OF ALLELIC VARIANTS - Disclosed herein are antisense compounds and methods for selectively reducing expression of an allelic variant of a huntingtin gene containing a single nucleotide polymorphism (SNP). Such methods, compounds, and composition are useful to treat, prevent, or ameliorate Huntington's Disease (HD). | 02-21-2013 |
20150292015 | SELECTIVE REDUCTION OF ALLELIC VARIANTS - Disclosed herein are antisense compounds and methods for selectively reducing expression of an allelic variant of a huntingtin gene containing a single nucleotide polymorphism (SNP). Such methods, compounds, and composition are useful to treat, prevent, or ameliorate Huntington's Disease (HD). | 10-15-2015 |
20150329859 | SELECTIVE REDUCTION OF ALLELIC VARIANTS - Disclosed herein are antisense compounds and methods for selectively reducing expression of an allelic variant of a gene containing a single nucleotide polymorphism (SNP). Such methods, compounds, and composition are useful to treat, prevent, or ameliorate diseases, including neurodegenerative diseases, such as Huntington's Disease (HD). | 11-19-2015 |
Patent application number | Description | Published |
20100298359 | GAMMA SECRETASE MODULATORS - This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula (I) wherein R | 11-25-2010 |
20110015190 | GAMMA SECRETASE MODULATORS - This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula (I) wherein R | 01-20-2011 |
20140206715 | PREPARATION AND USE OF COMPOUNDS AS PROTEASE INHIBITORS - Disclosed are compounds of the formula I | 07-24-2014 |
20140219989 | FACTOR IXA INHIBITORS - The present invention provides a compound of Formula (I) as described herein, or a pharmaceutically acceptable salt thereof. The present invention also provides pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes. | 08-07-2014 |
20140296311 | GAMMA SECRETASE MODULATORS - Disclosed herein are compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein each of the substituents is given the definition as set forth in the specification and claims. Also disclosed are pharmaceutical compositions containing compounds of Formula (I) and use of the compounds in the treatment of neurodegenerative diseases or conditions such as Alzheimer's disease. | 10-02-2014 |