Kirby, GB
Andrew James Kirby, Cardiff GB
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20080299290 | Method of Producing a Microneedle or Microimplant - A method of manufacturing microneedles is provided, the method includes (i) depositing a substance onto a first surface and (ii) forming a solid needle-like shape from the substance. The substance may be deposited in non-solid form and subsequently solidified. A method provides an array of such microneedles. | 12-04-2008 |
20110112502 | NEEDLELESS DEVICE FOR DELIVERY OF AN AGENT THROUGH A BIOLOGICAL BARRIER - A needleless device ( | 05-12-2011 |
Andy Kirby, Derbyshire GB
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20130105014 | ADJUSTABLE PILOT-ACTUATED VALVE | 05-02-2013 |
Anthony Kirby, Oxfordshire GB
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20090077415 | CONTROL FLOW PROTECTION MECHANISM - A method is provided of protecting a program executing on a device at least to some extent from execution flow errors caused by physical disturbances, such as device failures and voltage spikes, that cause program execution to jump to an unexpected memory location. The executing program follows an execution path that proceeds through a plurality of regions (B′[m], B′[f]). A first check value (wisb) is provided at a randomly accessible memory location. It is determined at least once (e.g. in TERM[m]) in at least one region (B′[m]) whether the first check value (wisb) has an expected value (s[m]) for that region (B′[m]). The first check value (wisb) is updated (e.g. in “set-up for call to f”), as execution passes from a first region (B′[m]) into a second region (B′[f]) in which such a determination is made, so as to have a value (s[f]) expected in the second region (B′[f]). An error handling procedure is performed if such a determination is negative. | 03-19-2009 |
Chris Kirby, Reading GB
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20120034297 | Pharmaceutical dosage forms comprising 6'-fluoro-(N-methyl- or N,N-dimethyl-)-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3- ,4,b]indol]-4-amine - A pharmaceutical dosage form for administration twice daily, once daily or less frequently, which contains 6′-fluoro-(N-methyl- or N,N-dimethyl)-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine or a physiologically acceptable salt thereof. | 02-09-2012 |
20150111939 | Pharmaceutical Dosage Forms Comprising 6'-Fluoro-(N-Methyl- or N,N-Dimethyl-)-4-Phenyl-4',9'-Dihydro-3'H-Spiro[Cyclohexane-1,1'-Pyrano[3- ,4,b]Indol]-4-Amine - A pharmaceutical dosage form for administration twice daily, once daily or less frequently, which contains 6′-fluoro-(N-methyl- or N,N-dimethyl)-4-phenyl-4′,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine or a physiologically acceptable salt thereof. | 04-23-2015 |
Clifford Ian Kirby, Merseyside GB
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20110278281 | HYPODERMIC NEEDLE DESTRUCTION - Disclosed is an apparatus for processing a hypodermic needle ( | 11-17-2011 |
Dan D. Kirby, Dartford GB
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20150251536 | FRONT END ACCESSORY DRIVE BRACKET AND MOUNTING METHOD FOR AN ENGINE - Methods and systems are provided for a bracket and surrounding structure for mounting a front end accessory drive component, such as an alternator, to an engine. Hanging heavy components on brackets may be dangerous and difficult for human operators as well as violate assembly standards. To securely hold the component to the engine in order to withstand vibrations and to protect the operator, an open bracket with a curved lip and surrounding support structure is used to mount the component to the engine. | 09-10-2015 |
Dean John Kirby, Leeds GB
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20110156352 | GASKET - A gasket for sealing two mating surfaces is described. The gasket has: | 06-30-2011 |
Dean John Kirby, Leeds, West Yorkshire GB
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20140042702 | A Gasket - Gaskets for sealing two mating surfaces are described. The gaskets have an outer portion including a core between two sealing layers and an inner portion made of a deformable material and located in an aperture in the outer portion. The thickness of the inner portion is greater than the thickness of the outer portion. The inner portion may include a chemical treatment agent that can provide chemical protection to the mating surfaces. Methods of producing the gaskets and methods of using the gaskets for sealing joints, including corroded joints, are also described. | 02-13-2014 |
Elizabeth Kirby, Wiltshire GB
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20090087877 | INFECTIVITY ASSAY - There is provided a method for infecting a target cell with a TSE agent, comprising: i) contacting said target cell with a membrane preparation, wherein the membrane preparation comprises the TSE agent and a donor membrane; and ii) infecting said target cell with the TSE agent. There is also provided a contiguous membrane, comprising a donor membrane and a membrane containing a TSE agent, wherein the TSE agent is selected from the group consisting of CJD, vCJD, familial CJD (e.g. FFI or CSS), iatrogenic CJD, BSE, ovine BSE, and CWD. | 04-02-2009 |
Ian Kirby, Hertfordshire GB
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20110256132 | MYOSTATIN BINDING PROTEINS - Description of antigen binding proteins, such as antibodies, which bind to myostatin, polynucleotides encoding such antigen binding proteins, pharmaceutical compositions comprising said antigen binding proteins and methods of manufacture. Furthermore, description of the use of such antigen binding proteins in the treatment or prophylaxis of diseases associated with anyone or a combination of decreased muscle mass, muscle strength and muscle function. | 10-20-2011 |
Ian Kirby, Cambridge GB
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20120167237 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 06-28-2012 |
20120204278 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 08-09-2012 |
20130042331 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 02-14-2013 |
20130318643 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 11-28-2013 |
20140120582 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 05-01-2014 |
20140134156 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 05-15-2014 |
20140150125 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 05-29-2014 |
20140150126 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 05-29-2014 |
20140182003 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 06-26-2014 |
20140201854 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 07-17-2014 |
20140201856 | ANIMAL MODELS AND THERAPEUTIC MOLECULES - The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods. | 07-17-2014 |
Ian Kirby, Stevenage GB
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20110200585 | CD127 BINDING PROTEINS - Antigen binding proteins which bind to human IL-7 receptor (CD127) are provided. The antigen binding proteins are typically antibodies, and are useful in the treatment of diseases or disorders in humans, particularly autoimmune diseases such as multiple sclerosis. | 08-18-2011 |
20120100137 | IMMUNOGLOBULINS - The present invention discloses humanised anti-IL-18 antibodies, methods of manufacture, and methods of treatment with said antibodies. Further disclosed are screening methods using for example surface plasmon resonance to identify antibodies with therapeutic potential. | 04-26-2012 |
20120282254 | CD127 BINDING PROTEINS - Antigen binding proteins which bind to human IL-7 receptor (CD127) are provided. The antigen binding proteins are typically antibodies, and are useful in the treatment of diseases or disorders in humans, particularly autoimmune diseases such as multiple sclerosis. | 11-08-2012 |
20130251724 | ANTIGEN BINDING PROTEINS TO ONCOSTATIN M (OSM) - The present invention concerns antigen binding proteins and fragments thereof which specifically bind Oncostatin M (OSM), particularly human OSM (hOSM) and which inhibit the binding of OSM to the gp130 receptor but does not directly interact with site II residues. The invention also concerns a method of humanising antibodies. Further disclosed are pharmaceutical compositions, screening and medical treatment methods. | 09-26-2013 |
20150064201 | ANTIGEN BINDING PROTEINS TO ONCOSTATIN M (OSM) - The present invention concerns antigen binding proteins and fragments thereof which specifically bind Oncostatin M (OSM), particularly human OSM (hOSM) and which inhibit the binding of OSM to the gp130 receptor but does not directly interact with site II residues. The invention also concerns a method of humanising antibodies. Further disclosed are pharmaceutical compositions, screening and medical treatment methods. | 03-05-2015 |
Ian John Kirby, Ayr GB
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20140352567 | EXPLOSIVE COMPOSITION - An explosive composition comprising a liquid energetic material and sensitizing voids, wherein the sensitizing voids are present in the liquid energetic material with a non-random distribution, wherein the liquid energetic material comprises (a) regions in which the sensitizing voids are sufficiently concentrated to render those regions detonable and (b) regions in which the sensitizing voids are not so concentrated and wherein the explosive composition does not contain ammonium nitrate prill. | 12-04-2014 |
20150218061 | METHOD OF CHARACTERISING THE STRUCTURE OF A VOID SENSITIZED EXPLOSIVE COMPOSITION - A method of characterising the structure of a void sensitized liquid energetic material, which method comprises defining the material in terms distribution function, the distribution function representing the fraction of liquid energetic material that occurs at a given point within the void sensitized liquid energetic material. | 08-06-2015 |
James M. Kirby, Malvern GB
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20080294439 | Speech screening - This invention relates to screening of spoken audio data so as to detect threat words or phrases. The method is particularly useful for protecting children or vulnerable adults from unsuitable content and/or suspicious or threatening contact with others via a communication medium. The method is applicable to screening speech transmitted over a computer network such as the internet and provides screening of access to stored content, e.g. audio or multimedia data files, as well as real time speech such as live broadcasts or communication via voice over IP or similar communication protocols. The method allows an administrator, e.g. a parent, to identify groups of threat words or phrases to be monitored, to set user access levels and to determine appropriate responses when threat words or phrases are detected. | 11-27-2008 |
James Michael Kirby, Malvern GB
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20120185473 | USER INTERFACE FOR USE IN NON-DETERMINISTIC SEARCHING - Apparatus for analysing non-deterministic results of a search query of data, comprising a processor and a user interface, the processor being operably in communication with a plurality of data sources and adapted to communicate with the user interface which enables the user to query the content of the data sources, wherein the processor is adapted to determine the probable relevance of at least the part of a searched data source for a user query and the user interface is adapted to present to the user the search results in a form comprising two or more portlets, wherein the portlets comprises two or more of: a portlet presenting the search results (suchas search strings) for a data source(s); a portlet presenting the data source (such as by source name) of a data soruce(s); a portlet presenting a data source filter tree for selecting currently active source(s); a portlet presenting the hit(s) of a search query for a data source; a portlet presenting the hit location within a data source; and at least one of the portlets presents the user with the probability of the relevance of the data source to the search query. | 07-19-2012 |
Jane Kirby, Alderley Edge GB
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20090302210 | MASS SPECTROMETER - A mass spectrometer comprising a collision, fragmentation or reaction cell ( | 12-10-2009 |
John Kirby, Newcastle Upon Tyne GB
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20100298203 | SDF-I-BASED GLYCOSAMINOGLYCAN ANTAGONISTS AND METHODS OF USING SAME - The present invention relates to novel mutants of human stromal cell-derived factor-1 which exhibit increased glycosaminoglycan (GAG) binding affinity and inhibited or down-regulated GPCR activity compared to wild type SDF-1, methods for producing these mutants and to their use for preparing medicaments for the treatment of cancer. | 11-25-2010 |
Jonathan Kirby, Horsham, West Sussex GB
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20150345129 | DAMP PROOF COURSE ARTICLE - A damp proof course article ( | 12-03-2015 |
Mark Kirby, Sheffield GB
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20090324347 | MILLING CUTTER MANUFACTURING METHOD - A method of manufacturing a milling cutter having a cutting head and a coaxial integral shank comprising the steps of grinding, in a first grinding operation, a plurality of helical flutes ( | 12-31-2009 |
20120170985 | FORM MILLING CUTTER FOR THE MACHINING OF TITANIUM ALLOYS ETC - A method of manufacturing a multi-tooth fir-tree or bulbous form milling cutter, by the grinding of a blank with a grinding wheel, wherein, a flat clearance angle Θ of between 0° and 20° is generated on each tooth ( | 07-05-2012 |
Miles Alexander Lyell Kirby, Ascot Berkshire GB
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20140292269 | WIRELESS POWER CHARGING TIMING AND CHARGING CONTROL - Exemplary embodiments are directed to timing and control of wireless power transfer. A wireless power charging device includes at least one transmitter and a processor in communication with the at least one transmitter. The transmitter is configured for transmitting wireless power to one or more electronic devices, and the processor is configured to deactivate the transmitter during a pre-determined time interval. The charging device may include charging modes that a user may select between from an interface of the charging device. Charging modes may be related to times of operation such as those based on a user schedule, based on energy rates, or with modes programmed by a user. A charging schedule may be created by a user through the interface of the charging device or from an external device in communication with the charging device. | 10-02-2014 |
20150137750 | SYSTEMS AND METHODS FOR WIRELESS POWER AND DATA TRANSFER FOR ELECTRONIC DEVICES - Exemplary embodiments are directed to wireless power. A wireless charging device may comprise a charging region configured for placement of one or more chargeable devices. The charging device may further include at least one transmit antenna configured for transmitting wireless power within the charging region. Furthermore, the charging device is configured to exchange data between at least one chargeable device of the one or more chargeable devices. | 05-21-2015 |
Raymond George Kirby, Bournemouth GB
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20110011882 | PRODUCT FEEDING APPARATUS - Automatic feeding machines are commonly used for filling blister packs with items of product such as pharmaceutical dosage forms. These machines are usually designed for the handling of a specific shape and sized product item. Handling of different shaped items requires expensive re-tooling of all the product item contact components. The invention allows a single feeding machine to be quickly configured for use to handling a wide variety of item sizes/shapes. A machine ( | 01-20-2011 |
Robert Kirby, Cambridge GB
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20140066426 | FLUOROMETHYL-SUBSTITUTED PYRROLE CARBOXAMIDES - The invention relates to pyrrole carboxamides bearing a fluoromethyl-moiety as voltage gated calcium channel blockers, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders. | 03-06-2014 |
Rupert Kirby, Alton GB
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20110050138 | Electric Motor and Electric Generator - An electric motor comprising a stator having two coil sets arranged to produce a magnetic field of the motor, each coil set comprising a plurality of coil sub-sets; and two control devices, wherein the first control device is coupled to the plurality of coil sub-sets for the first coil set and the second control device is coupled to the plurality of coil sub-sets for the second coil set and each control device is arranged to control current in the respective plurality of coil sub-sets to generate a magnetic field in each coil sub-set to have a substantially different magnetic phase to the other one or more coil sub-sets in the respective coil set; and wherein the first control device and the second control device are mounted adjacent to the stator. | 03-03-2011 |
Rupert Paul Kirby, Hants GB
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20130218436 | ELECTRIC MOTOR - An electric motor for rotating a wheel of a vehicle, the electric motor having a rotor, a stator and coil windings, a first sensor arranged to output a first signal indicative of a position of the rotor relative to the stator, a second sensor arranged to output a second signal indicative of a position of the rotor relative to the stator; wherein the first sensor and second sensor are offset with respect to each other such that upon rotation of the rotor relative to the stator the first output signal and second output signal allow the direction of the rotor to be determined; wherein the first output signal and second output signal are used for controlling current in the coil windings and at least one of the first output signal and second output signal are provided to a vehicle braking system to allow the vehicle braking system to determine a wheel lock condition or an onset of a wheel lock condition, wherein the onset of a wheel lock condition is determined based on predetermined criteria. | 08-22-2013 |
20140340013 | ELECTRIC MOTOR AND ELECTRIC GENERATOR - An electric motor with a stator having two coil sets arranged to produce a magnetic field of the motor, each coil set having a plurality of coil sub-sets; and two control devices, wherein the first control device is coupled to the plurality of coil sub-sets for the first coil set and the second control device is coupled to the plurality of coil sub-sets for the second coil set and each control device is arranged to control current in the respective plurality of coil sub-sets to generate a magnetic field in each coil sub-set to have a substantially different magnetic phase to the other one or more coil sub-sets in the respective coil set; and wherein the first control device and the second control device are mounted adjacent to the stator. | 11-20-2014 |
Rupert Paul Kirby, Farnham GB
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20130200746 | COIL TOOTH ASSEMBLY - A stator back-iron or rotor back-iron of an electric motor, for receiving coil windings comprises a support ( | 08-08-2013 |
Simon Kirby, Malvern Wells GB
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20120304406 | WASTE REMOVAL SYSTEM - A waste removal device comprises a body, a paddle ( | 12-06-2012 |
Stuart J. Kirby, Derby GB
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20090188257 | Aeroengine bleed valve - A bleed valve bleeds hot gases from a compressor into a bypass duct of a gas turbine engine. The valve comprises a diffuser having opposing walls and a divider located between the walls and which define at least two passages through which a bleed fluid flows and into a fluid flow through the bypass duct. The passages are angled towards each other to force the two gas flows together to form a high aspect ratio plume. This plume has a relatively large surface area that that improves mixing with the bypass flow to cool it and prevented otherwise hot bleed flows from impinging on heat sensitive components adjacent the bypass duct. | 07-30-2009 |
20100043447 | Bleed valve arrangement - Problems can arise with regard to noise created by bleed valve arrangements ( | 02-25-2010 |
20100115963 | Bleed assembly - A noise reduction device | 05-13-2010 |
20100115964 | Noise reduction device - A noise reduction device | 05-13-2010 |
20100260598 | THERMAL CONTROL SYSTEM FOR TURBINES - A thermal control system for a turbine casing ( | 10-14-2010 |
Stuart Mathew Kirby, Malvern Wells GB
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20120304406 | WASTE REMOVAL SYSTEM - A waste removal device comprises a body, a paddle ( | 12-06-2012 |