Patent application number | Description | Published |
20130087479 | PACKAGED ORAL CARE IMPLEMENT AND PACKAGE - A package for an oral care implement comprising a container having a display portion and a periphery, and a backing attached to the container for defining an interior for receiving an oral care implement. The backing further comprises a first portion attached to a portion of the periphery for defining an interior of the container and a second portion attached to the display portion; wherein the second portion of the backing further comprises a separable portion that facilitates separation of the first portion of the backing from the display portion and thereby facilitates access to the interior of the container. | 04-11-2013 |
20150327668 | ORAL CARE IMPLEMENT HAVING PRESSURE SENSOR AND METHOD OF FORMING THE SAME - A toothbrush having a pressure sensor. In one embodiment, the invention can comprise a body comprising a handle portion and a head portion having a basin; a cleaning assembly comprising: a head plate; a plurality of tooth cleaning elements, each of the plurality of tooth cleaning elements comprising a cleaning portion extending from a front surface of the head plate and a base portion extending from a rear surface of the head plate; the base portions of the plurality of tooth cleaning elements melted together to form a melt matte adjacent the rear surface of the head plate; the head plate of the cleaning element assembly positioned in the basin and connected to the head portion; a pressure sensor adjacent a rear surface of the melt matte; and an indicator operably coupled to the pressure sensor for generating a user perceptive signal upon the pressure sensor sensing a pressure that exceeds a predetermined threshold. | 11-19-2015 |
20150335145 | ORAL CARE IMPLEMENT AND METHOD OF MANUFACTURING AN ORAL CARE IMPLEMENT - A method of manufacturing an oral care implement, comprises: (a) providing a head and a first part of a handle connected to the head, the first part having a first surface; (b) providing the head with at least one cleaning element; and (c) attaching a second part of the handle to the first part of the handle, which second part has a second surface and houses an assembly comprising a timer and a user-notification device that is configured to output a notification in dependence on a state of the timer, so that the first part is connected to the head at a distal end of the handle, the second part defines a proximal end of the handle, and the first and second surfaces together define an exterior surface of the handle. | 11-26-2015 |
20150342337 | ORAL CARE IMPLEMENT COMPRISING MIRROR AND LIGHT DISTRIBUTIVE ELEMENT, AND METHOD OF FORMING THE SAME - An oral care implement, such as a toothbrush, that comprises a mirror and a light pipe adjacent the mirror. In one embodiment, the invention can be an oral care implement comprising a body comprising a handle portion and a head portion; a mirror coupled to the body; a light source coupled to the body, and a light pipe coupled to the body and surrounding at least a portion of the mirror, the light pipe operably coupled to the light source to distribute light emitted by the light source through the light pipe. | 12-03-2015 |
Patent application number | Description | Published |
20080236616 | METHOD AND APPARATUS FOR COMMISSIONING POWER PLANTS - An apparatus and method for commissioning steam turbine generator power plants to advance the cleanliness of the complete steam cycle by the conditioned discharge of steam to the plant surface condenser. | 10-02-2008 |
20140174477 | METHOD AND APPARATUS FOR COMMISSIONING POWER PLANTS - An apparatus and method for commissioning steam turbine generator power plants to advance the cleanliness of the complete steam cycle by the conditioned discharge of steam to the plant surface condenser. | 06-26-2014 |
20140174559 | METHOD AND APPARATUS FOR COMMISSIONING POWER PLANTS - An apparatus and method for commissioning steam turbine generator power plants to advance the cleanliness of the complete steam cycle by the conditioned discharge of steam to the plant surface condenser. | 06-26-2014 |
20140230862 | METHOD AND APPARATUS FOR COMMISSIONING POWER PLANTS - An apparatus and method for commissioning steam turbine generator power plants to advance the cleanliness of the complete steam cycle by the conditioned discharge of steam to the plant surface condenser. | 08-21-2014 |
20140237839 | METHOD AND APPARATUS FOR COMMISSIONING POWER PLANTS - An apparatus and method for commissioning steam turbine generator power plants to advance the cleanliness of the complete steam cycle by the conditioned discharge of steam to the plant surface condenser. | 08-28-2014 |
20140238507 | METHOD AND APPARATUS FOR COMMISSIONING POWER PLANTS - An apparatus and method for commissioning steam turbine generator power plants to advance the cleanliness of the complete steam cycle by the conditioned discharge of steam to the plant surface condenser. | 08-28-2014 |
Patent application number | Description | Published |
20100318623 | Method of Controlling Access to Network Resources Using Information in Electronic Mail Messages - A method and apparatus for controlling access to network resources referenced in electronic mail messages comprises the computer-implemented steps of receiving an electronic mail message that comprises one or more hyperlinks; determining sender information that identifies a sender of the electronic mail message; creating and storing a record that associates the sender information with each of the one or more hyperlinks; receiving a request to access a specified hyperlink among the one or more hyperlinks; retrieving, based on the specified hyperlink, the record; retrieving, based on the sender information associated with the specified hyperlink, sender reputation information associated with the sender; determining, based on the sender reputation information, a particular action among a plurality of allowed actions; and issuing a network request to access the specified hyperlink only when the particular action is allowing user access to the specified hyperlink. | 12-16-2010 |
20110078309 | Apparatus for Filtering Server Responses - A data processing apparatus, comprising at least one processor and a traffic monitor comprising logic which, when executed by the processor, causes the processor to perform: creating, using forward Domain Name System (DNS) lookups, a mapping of domain names to Internet Protocol (IP) addresses; determining whether a particular domain in the mapping requires handling data traffic to or from the particular domain by performing a particular action; based on the mapping, determining one or more IP addresses that are associated with the particular domain; generating policy for a firewall that instructs the firewall to perform the particular action upon receiving a particular request; wherein the particular request specifies a particular IP address that is within the particular domain. | 03-31-2011 |
Patent application number | Description | Published |
20140078397 | Systems and Methods for Constructing Multimedia Content Modules - A system for constructing seamlessly viewable multimedia content from selectably presentable multimedia content blocks includes a block definition module for facilitating creation and modification of the content blocks. The block definition module includes a media assignment submodule for associating a synchronized audio and video segment with a content block. Also included is a block linking submodule for creating seamless connections between content blocks, whereby a transition between the connected blocks occurs substantially without interruption upon viewing the multimedia content. The block definition module further includes a layer submodule for associating an interactive layer having interactive controls with the content block. | 03-20-2014 |
20140082666 | PROGRESS BAR FOR BRANCHED VIDEOS - A system for navigating and visualizing the progression of selectably presentable video content includes a progress indicator module for dynamically displaying the progression status of video content paths made up of selectably presentable video content segments. The system further includes an interactive control module for facilitating navigation along the video content paths. The progression status may be graphically represented in the form of a tree structure having linked video content segments forming the content paths. The control module may be used to navigation the video within this tree structure. | 03-20-2014 |
20140178051 | SYSTEMS AND METHODS FOR LOADING MORE THAN ONE VIDEO CONTENT AT A TIME - A system for loading videos includes an interactive video player is with a loader. A product configuration file in operation configures files for a user in creation of a custom video. External assets are configured for a design of an interactive layer of the video. The interactive video player in operation creates in real-time a custom video that includes a plurality of video segments. | 06-26-2014 |
20140380167 | Systems and methods for multiple device interaction with selectably presentable media streams - A system for multiple device interaction with selectably presentable multimedia content includes an output engine, an input engine, a manager, and a memory that stores selectably presentable multimedia content segments. Each content segment represents a predefined portion of one or more content paths. The output engine, executing on a first device, receives a subset of the content segments, assembles them into a seamless multimedia presentation that is one of the content paths, and plays the assembled multimedia presentation. The input engine, executing on a second device, receives user interactions associated with the multimedia presentation, and the manager coordinates the multimedia presentation among multiple devices based on the user interactions. A method implementing the above steps is also included. | 12-25-2014 |
20150067723 | METHODS AND SYSTEMS FOR UNFOLDING VIDEO PRE-ROLL - Method and accompanying system for an unfolding video pre-roll. A primary video having a fixed play length is presented and, in temporal proximity to at least a portion of the primary video, an unfolding video having a variable play length is presented to the viewer. If an interaction is received from the viewer during the playback of the unfolding video, the play length of the unfolding video is extended by adding a seamlessly connected video segment to the unfolding video, which is continuously presented to the viewer without interruption. | 03-05-2015 |
20150104155 | SYSTEMS AND METHODS FOR REAL-TIME PIXEL SWITCHING - Systems and accompanying methods are provided for real-time pixel switching in video. A video having first and second portions is provided and is presented to a user, with the first video portion being initially visible to the user and the second video portion not initially visible to the user. During presentation of the video, a user interaction with the first video portion is received, and a selected region of the second video portion is identified based thereon, where the selected region defines a subset of pixels from the second video portion. The selected region is then overlaid on the first video portion, and playback of the second video portion and the first video portion is synchronized. | 04-16-2015 |
20150179224 | METHODS AND SYSTEMS FOR SEEKING TO NON-KEY FRAMES - Methods and systems for seeking to a non-key frame in a compressed video. The compressed video has a plurality of frames, each with a playback timestamp. At least one of the frames is a key frame. A selection of a non-key frame is received, and a temporally proximate key frame is identified. The set of frames between the identified key frame and the selected frame is played in a reduced time interval, and the selected frame is displayed as if it were a key frame. | 06-25-2015 |
20150181301 | METHODS AND SYSTEMS FOR IN-VIDEO LIBRARY - Method and accompanying system for providing an in-video library. A video player presents a video stream to a user. During presentation of the video stream, the video player displays at least a portion of a library of selectable prerecorded video segments, and a selection of one or more of the prerecorded video segments from the library is received from the user. The video player further displays a video segment watch-list that includes the selected prerecorded video segments. The video player then presents the segments in the video segment watch-list as part of the video stream. | 06-25-2015 |
20150199116 | PROGRESS BAR FOR BRANCHED VIDEOS - A system for navigating and visualizing the progression of selectably presentable video content includes a progress indicator module for dynamically displaying the progression status of video content paths made up of selectably presentable video content segments. The system further includes an interactive control module for facilitating navigation along the video content paths. The progression status may be graphically represented in the form of a tree structure having linked video content segments forming the content paths. The control module may be used to navigation the video within this tree structure. | 07-16-2015 |
20150293675 | DYNAMIC TIMELINE FOR BRANCHED VIDEO - Systems and methods for editing and controlling video playback using a dynamic timeline. The dynamic timeline allows a user to edit a video content structure that includes a plurality of video content paths, each video content path including a plurality of video content segments. The video content segments in a first video content path are visually represented on the dynamic timeline. A selection in the dynamic timeline is received that changes a first video content segment from the first video content path to a second video content segment in an alternative video content path in the video content structure. Subsequently, the dynamic timeline is updated to display visual representations of at least some of the video content segments in the alternative video content path. | 10-15-2015 |
20150294685 | SYSTEMS AND METHODS FOR CREATING LINEAR VIDEO FROM BRANCHED VIDEO - Computer-implemented methods and systems for creating non-interactive, linear video from video segments in a video tree. Selectably presentable video segments are stored in a memory, with each segment representing a predefined portion of one or more paths in a traversable video tree. A linear, non-interactive video is automatically created from the selectably presentable video segments by traversing at least a portion of a first path in the video tree and, upon completion, is provided to a viewer for playback. | 10-15-2015 |
20160104513 | SYSTEMS AND METHODS FOR DYNAMIC VIDEO BOOKMARKING - Methods and systems for dynamic bookmarking in branched video are described. An application provides a video tree having a plurality of video segments, with each video segment including a predefined portion of one or more paths in the video tree, and each path being associated with a different video presentation. One of the paths in the video tree is traversed based on one or more decisions made by a user during playback of the video presentation associated with the path being traversed. A selection of a particular location in the path being traversed is received by the application, which stores a bookmark of the location for subsequent retrieval. The bookmark identifies a sequence of video segments in the video tree having been traversed to reach the location. The structure of the video tree is modified, and the bookmark is automatically updated, if necessary. At a later time, the application receives a selection of the stored bookmark and seeks to the bookmarked location. The application further restores the decisions made by the user during the previous playback of the presentation. | 04-14-2016 |
20160105724 | SYSTEMS AND METHODS FOR PARALLEL TRACK TRANSITIONS - Methods and systems for parallel video track transitions are described. A plurality of video streams is simultaneously received, with each stream including a plurality of portions. A video comprising a first portion of a first one of the video streams is presented. Prior to completing the presentation of the first portion, a second portion of the first video stream is appended onto the video. Then, prior to completing the presentation of the second portion, a second video stream is selected based on a user interaction received with respect to the video, and a portion of the second video stream is appended onto the video. | 04-14-2016 |
Patent application number | Description | Published |
20140011805 | INHIBITORS OF THE BMP SIGNALING PATHWAY - The present invention provides small molecule inhibitors of BMP signaling. These compounds may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with BMP signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as for modulating cellular differentiation and/or proliferation. | 01-09-2014 |
20140038953 | COMPOSITIONS AND METHODS FOR CARDIOVASCULAR DISEASE - The present invention provides small molecule inhibitors of BMP signaling. These compounds may be used to reduce circulating levels of ApoB-100 or LDL. These compounds may also be used to treat or prevent acquired or congenital hypercholesterolemia or hyperlipoproteinemia; diseases, disorders, or syndromes associated with defects in lipid absorption or metabolism; or diseases, disorders, or syndromes caused by hyperlipidemia. | 02-06-2014 |
20150133521 | INHIBITORS OF MICRORNAs THAT REGULATE PRODUCTION OF ATRIAL NATRIURETIC PEPTIDE (ANP) AS THERAPEUTICS AND USES THEREOF - The present invention relates to methods, kits and compositions to treat hypertension and other cardiovascular diseases in a subject, in particular, a method of treating or preventing a cardiovascular disease in a subject comprising administering to a subject at least one anti-miR agent to miRNA-425. In some embodiments, an anti-miR agent is a small molecule or an oligonucleotide complementary to at least part of the miR-425 of SEQ ID NO: 1, or an anti-miR complementary to at least part of the miRNA seed sequence AUGACA (SEQ ID NO: 2). Another aspect of the present invention relates to methods, kits and compositions to treat low blood pressure in a subject comprising administering a composition comprising a miR-425 agent to decrease ANP levels in the subject. Other aspects of the present invention relates to assays, methods and systems to identify a subject at risk of hypertension, or identifying a subject suitable to administration of an anti-miR-425 agent for treatment of hypertension, the assay comprising assessing if a subject is homozygous or heterozygous for the major (A) allele of rs5068 SNP, and/or assaying for levels of miR-425 and/or assaying for levels of NT-proANP and/or levels of ANP in the plasma of a subject. | 05-14-2015 |
Patent application number | Description | Published |
20100306169 | Apparatus, Method and System For Improving Application Performance Across a Communication Network - An apparatus, method and system to enable dynamic replication of Web servers across a wide area in response to access patterns by Web clients as well as in response to customer requests. The method for dynamically replicating one or more parent nodes on a network in response to a user request by a policy manager. The policy manager transmits the user request to an event module. The event module transmits the user request to a data consistency module, wherein the data consistency module maintains integrity of the data on the parent node. The event system communicates with a resource management module to ensure proper utilization of network resources, and transmits the routing request to a request routing module for appropriately balancing the network load. The request routing module is capable of providing optimal routing based on the network resources. | 12-02-2010 |
20130031250 | APPARATUS, METHOD AND SYSTEM FOR IMPROVING APPLICATION PERFORMANCE ACROSS A COMMUNICATIONS NETWORK - An apparatus, method and system to enable dynamic replication of Web servers across a wide area in response to access patterns by Web clients as well as in response to customer requests. The method for dynamically replicating one or more parent nodes on a network in response to a user request by a policy manager. The policy manager transmits the user request to an event module. The event module transmits the user request to a data consistency module, wherein the data consistency module maintains integrity of the data on the parent node. The event system communicates with a resource management module to ensure proper utilization of network resources, and transmits the routing request to a request routing module for appropriately balancing the network load. The request routing module is capable of providing optimal routing based on the network resources. | 01-31-2013 |
20130036221 | APPARATUS, METHOD AND SYSTEM FOR IMPROVING APPLICATION PERFORMANCE ACROSS A COMMUNICATIONS NETWORK - An apparatus, method and system to enable dynamic replication of Web servers across a wide area in response to access patterns by Web clients as well as in response to customer requests. The method for dynamically replicating one or more parent nodes on a network in response to a user request by a policy manager. The policy manager transmits the user request to an event module. The event module transmits the user request to a data consistency module, wherein the data consistency module maintains integrity of the data on the parent node. The event system communicates with a resource management module to ensure proper utilization of network resources, and transmits the routing request to a request routing module for appropriately balancing the network load. The request routing module is capable of providing optimal routing based on the network resources. | 02-07-2013 |
Patent application number | Description | Published |
20090280517 | METHODS OF DIAGNOSIS AND PROGNOSIS FOR A MUSCULAR DYSTROPHY - The invention relates to the treatment, diagnosis, and prognosis of a muscular dystrophy or myopathy. The present inventors have found that the quantity of mu-crystallin is increased in a muscular dystrophy. In particular, the inventors have found that mu-crystallin is increased in facioscapulohumeral muscular dystrophy (FSHD). Based on the inventors' findings, the invention provides a novel means for the treatment, diagnosis, and prognosis of a muscular dystrophy or myopathy. | 11-12-2009 |
20120010531 | Small-Animal Unit for Muscle Injury, Muscle Testing and Muscle Training in Vivo - The invention provides a system for measuring contractile torque of skeletal muscles, performing muscle training programs, and inducing contraction-induced injury. The system is versatile and precise to measure contractile torque, train muscles, and perform contraction-induced injury protocols on living rodents. The system also allows for repeated studies of the same animal over time, thus resembling longitudinal human studies, minimizing the effect of animal-to-animal variability, and reducing the total number of animals that need to be studied. | 01-12-2012 |
Patent application number | Description | Published |
20080247023 | Method and apparatus for maximum light intensity for an optical illumination system - An illumination system using, in place of a more typical beam splitter, two right angle triangular prisms that are aligned to each other along their respective hypotenuses to form a cube, but without any reflective materials being used at their interface, and with the two halves separated by some distance so as to create an open/air gap between the two halves. When the upper/lower cube faces are normal to an optical axis of the illumination system, the cube structure reflects virtually all of the illumination from a transverse illumination source using total internal reflection so that said illumination is reflected out of the cube along the system's optical axis. However, rotating the cube structure past the critical angle eliminates total internal reflection and allows the cube to transmit almost all illumination entering the cube out of the cube parallel to the system's optical axis. | 10-09-2008 |
20080304168 | SYSTEM AND METHOD FOR FOCAL LENGTH STABILIZATION USING ACTIVE TEMPERATURE CONTROL - An optical metrological system having a heat-generating light source coaxially mounted near a heat-sensitive lens. The system uses a temperature sensor to monitor the lens temperature and a heating element to heat the lens such that the lens operating temperature is greater than a maximum operating temperature of the light source in order to stabilize the focal length of the lens. | 12-11-2008 |
20090096912 | High performance front objective for video metrological system - This high performance front objective lens system intended primarily for use with a video inspection apparatus has a first lens set in the form of a doublet, with a second lens set intermediate the first lens set and the imaging plane. The second lens set includes a doublet and an adjacent lens. The overall system has an effective focal length of 50 mm, a front focal length of 38.75 mm, and a numerical aperture greater than 0.2. Further, the material of the doublets is chosen to have a small, gradual transition in index between the elements of the lens and the cement, minimizing back reflections and thereby eliminating the need for index matching coatings on the cemented surfaces of the doublets. Finally, the imaging plane of the system matches that of standard ring lights used with video inspection apparatus. | 04-16-2009 |
20120127468 | THROUGH-THE-LENS ILLUMINATOR FOR OPTICAL COMPARATOR - An illumination system shares portions of an objective of an optical inspection system. A plurality of beam-shaping optics collects light from a plurality of effective light sources and directs the light through a portion of the objective for illuminating an object under inspection. The objective includes a front relay lens, a rear relay lens, and an objective stop disposed between the front and rear relay lenses for collecting light scattered from the object and forming an image of the object with the collected light. The beam-shaping optics, which surround the objective stop, are arranged together with the associated effective light sources for non-uniformly distributing light within a range of angles required for illuminating the object. | 05-24-2012 |
20120262707 | THROUGH-THE-LENS ILLUMINATOR FOR OPTICAL COMPARATOR - An illumination system shares portions of an objective of an optical inspection system. A plurality of beam-shaping optics collects light from a plurality of effective light sources and directs the light through a portion of the objective for illuminating an object under inspection. The objective includes a front relay lens, a rear relay lens, and an objective stop disposed between the front and rear relay lenses for collecting light scattered from the object and forming an image of the object with the collected light. The beam-shaping optics, which surround the objective stop, are arranged together with the associated effective light sources for non-uniformly distributing light within a range of angles required for illuminating the object. | 10-18-2012 |
Patent application number | Description | Published |
20080213859 | Methods for the Reduction of Stutter in Microsatellite Amplification - The invention provides a method for reducing stutter in the amplification of a microsatellite comprising the steps of providing a sample comprising a microsatellite having a G+C content of 50% or less; contacting the sample with at least one enzyme having nucleic acid polymerase activity; and incubating the sample with the enzyme for a sufficient amount of time and under conditions sufficient to amplify the microsatellite; wherein the incubation is performed in the presence of an amount of betaine, sorbitol or mixtures thereof, effective to reduce stutter relative to the amount of stutter observed in the absence of betaine and/or sorbitol. The invention also provides compositions containing betaine and/or sorbitol, kits for amplifying microsatellites having a G+C content of 50% or less, and methods of using all of the foregoing. | 09-04-2008 |
20090269815 | LINEAR AMPLIFICATION OF SHORT NUCLEIC ACIDS - The present teachings provide novel methods for amplifying short nucleic acids. In some embodiments, the present teachings provide novel methods for linearly amplifying a collection of micro RNAs by using temperature cycling during a reverse transcription reaction. The cycling can comprise at least 20 cycles of an annealing temperature segment of 10° C.-30° C., and a denaturation temperature segment of 35° C.-60° C. In some embodiments, the temperature cycled reaction can comprise an osmolyte. | 10-29-2009 |
20110143352 | Methods for the Reduction of Stutter in Microsatellite Amplification - The invention provides a method for reducing stutter in the amplification of a microsatellite comprising the steps of providing a sample comprising a microsatellite having a G+C content of 50% or less; contacting the sample with at least one enzyme having nucleic acid polymerase activity; and incubating the sample with the enzyme for a sufficient amount of time and under conditions sufficient to amplify the microsatellite; wherein the incubation is performed in the presence of an amount of betaine, sorbitol or mixtures thereof, effective to reduce stutter relative to the amount of stutter observed in the absence of betaine and/or sorbitol. The invention also provides compositions containing betaine and/or sorbitol, kits for amplifying microsatellites having a G+C content of 50% or less, and methods of using all of the foregoing. | 06-16-2011 |
20130011839 | Methods for the Reduction of Stutter in Microsatellite Amplification - The invention provides a method for reducing stutter in the amplification of a microsatellite comprising the steps of providing a sample comprising a microsatellite having a G+C content of 50% or less; contacting the sample with at least one enzyme having nucleic acid polymerase activity; and incubating the sample with the enzyme for a sufficient amount of time and under conditions sufficient to amplify the microsatellite; wherein the incubation is performed in the presence of an amount of betaine, sorbitol or mixtures thereof, effective to reduce stutter relative to the amount of stutter observed in the absence of betaine and/or sorbitol. The invention also provides compositions containing betaine and/or sorbitol, kits for amplifying microsatellites having a G+C content of 50% or less, and methods of using all of the foregoing. | 01-10-2013 |
20140186893 | Linear Amplification of Short Nucleic Acids - The present teachings provide novel methods for amplifying short nucleic acids. In some embodiments, the present teachings provide novel methods for linearly amplifying a collection of micro RNAs by using temperature cycling during a reverse transcription reaction. The cycling can comprise at least 20 cycles of an annealing temperature segment of 10° C.-30° C., and a denaturation temperature segment of 35° C.-60° C. In some embodiments, the temperature cycled reaction can comprise an osmolyte. | 07-03-2014 |
20150024387 | Methods for the Reduction of Stutter in Microsatellite Amplification - The invention provides a method for reducing stutter in the amplification of a microsatellite comprising the steps of providing a sample comprising a microsatellite having a G+C content of 50% or less; contacting the sample with at least one enzyme having nucleic acid polymerase activity; and incubating the sample with the enzyme for a sufficient amount of time and under conditions sufficient to amplify the microsatellite; wherein the incubation is performed in the presence of an amount of betaine, sorbitol or mixtures thereof, effective to reduce stutter relative to the amount of stutter observed in the absence of betaine and/or sorbitol. The invention also provides compositions containing betaine and/or sorbitol, kits for amplifying microsatellites having a G+C content of 50% or less, and methods of using all of the foregoing. | 01-22-2015 |