Patent application number | Description | Published |
20100292244 | HYDROXYLATED PYRIMIDYL CYCLOPENTANE AS AKT PROTEIN KINASE INHIBITOR - The present invention provides a compound and pharmaceutically acceptable salts thereof, comprising the Formula I. Also provided are methods of using the compound of this invention as an AKT protein kinase inhibitor and for the treatment of hyperproliferative diseases such as cancer. | 11-18-2010 |
20110053959 | PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds of Formula (I) including tautomers, resolved enantiomers, resolved diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as Akt protein kinase inhibitors and for the treatment of Akt-mediated diseases, for example, hyperproliferative diseases such as cancer. | 03-03-2011 |
20110065716 | HYDROXYLATED PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds, including pharmaceutically acceptable salts thereof, comprising the Formula (I): Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases, such as cancer. | 03-17-2011 |
20110251181 | 5H-CYCLOPENTA[D]PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS - Compounds of Formula I are useful for inhibiting AKT protein kinases. Methods using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. Formula (I). | 10-13-2011 |
20120178715 | SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS mTOR INHIBITORS - Compounds of Formula I: and salts thereof in which R | 07-12-2012 |
20120232055 | HYDROXYLATED AND METHOXYLATED PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula I: | 09-13-2012 |
20130065908 | DIHYDROFURO PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: | 03-14-2013 |
20130072500 | PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds of Formula I including tautomers, resolved enantiomers, resolved diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. | 03-21-2013 |
20130085135 | 5H-CYCLOPENTA[D]PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS - Compounds of Formula I are useful for inhibiting AKT protein kinases. Methods of using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. | 04-04-2013 |
20130143865 | PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds of Formula I, including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. | 06-06-2013 |
20140005213 | TRIAZOLOPYRIDINE COMPOUNDS AS PIM KINASE INHIBITORS | 01-02-2014 |
20140080829 | PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds of Formula I, including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. | 03-20-2014 |
20140148436 | AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: | 05-29-2014 |
20140315887 | PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds of Formula I, including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. | 10-23-2014 |
20140349996 | PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds of Formula I, including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. | 11-27-2014 |
20140349997 | HYDROXYLATED AND METHOXYLATED PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula I: | 11-27-2014 |
20140357644 | HYDROXYLATED PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds, including pharmaceutically acceptable salts thereof, comprising the Formula I: | 12-04-2014 |
20150051217 | HYDROXYLATED PYRIMIDYL CYCLOPENTANE AS AKT PROTEIN KINASE INHIBITOR - The present invention provides a compound and pharmaceutically acceptable salts thereof, comprising the Formula I: | 02-19-2015 |
20150191479 | DIHYDROFURO PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: | 07-09-2015 |
20150197496 | PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds of Formula I, including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. | 07-16-2015 |
20150266852 | 5H-CYCLOPENTA[d]PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS - Compounds of Formula I are useful for inhibiting AKT protein kinases. Methods of using compounds of Formula I and stereoisomers and pharmaceutically acceptable salts thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed. | 09-24-2015 |
Patent application number | Description | Published |
20100168123 | AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: | 07-01-2010 |
20110015204 | PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds of Formula (I), including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer. | 01-20-2011 |
20110160221 | PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds of Formula I, including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer. | 06-30-2011 |
20110245230 | PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds of Formula I, including tautomers, resolved enantiomers, diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. | 10-06-2011 |
20120329808 | DIHYDROTHIENO PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS - The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: | 12-27-2012 |
Patent application number | Description | Published |
20080232346 | METHOD, SYSTEM AND APPARATUS FOR SYNCHRONIZING STREAM BETWEEN BEARER CONTROL LAYER AND BEARER LAYER DEVICES - A method, a system and an apparatus for synchronizing the stream between the bearer control layer and bearer layer devices. Bearer layer device returns information corresponding to the stream synchronizing information distributed by the resource manager RM of the bearer control layer back to the resource manager RM ( | 09-25-2008 |
20130012670 | SEALANT OF LIQUID CRYSTAL PANEL AND MODIFICATION METHOD THEREFOR - A sealant of a liquid crystal panel and a modification method therefor are disclosed. The sealant contains modified epoxy resins which is formed by a cross-linking and curing reaction between isocyanate-terminated tri-functional monomers and epoxy monomers. The modified epoxy resin has a plurality of trifurcate cross-linking long-chain structures, and each of the trifurcate cross-linking long-chain structures has three isocyanate groups, each of which is flexibly linked to one or more molecular groups of epoxy resin. The modified epoxy resin can enhance the adhesion property of the epoxy resin with surfaces of glass substrates and the stress-and-cracking resistance of the epoxy resin, while it can efficiently prevent from the miscible material problem between the epoxy resin and the liquid crystal material, so as to relatively lower the possibility of contaminating the liquid crystal material. | 01-10-2013 |
20150140667 | METHOD FOR MEASURING MOISTURE IN LIQUID CRYSTALS - When measuring the liquid crystals under test, the present invention adding the liquid crystals under test to a mixed solvent to form a solvent under test; measuring the moisture in the liquid crystal measurement sample through a reaction reagent to achieve a measurement result; wherein the mixed solvent comprises a first solvent, and the first solvent is dissolved with the methanol of the reaction reagent mutually and dissolves the liquid crystals under test. In the present invention, the moisture in the liquid crystal can be fully released and achieve accurate measurements. | 05-21-2015 |
20150225592 | Base Film of Modified Polyvinyl Alcohol and Its Preparation Method and Polarizer - The present invention provides a base film of modified polyvinyl alcohol as well as a method for preparing the base film of modified polyvinyl alcohol and a polarizer made from the base film. The method includes steps of: (1) executing surface graft modification of nano-silicon dioxide particles with fluorinated silane to obtain a modified nano-silicon dioxide powder; (2) adding the modified nano-silicon dioxide powder obtained from the step (1) to an aqueous solution of polyvinyl alcohol polymer, in order to prepare a composite solution of polyvinyl alcohol polymer; and (3) pouring the composite solution of polyvinyl alcohol polymer prepared from the step (2) onto a surface of a casting substrate to obtain a base film of modified polyvinyl alcohol (PVA). The present invention enhances the heat and humidity resistances and the stability of the PVA base film, and improves its mechanical performance and sticking-resistance. | 08-13-2015 |
20150260651 | DEVICE AND METHOD FOR MEASURING CONCENTRATION OF ETCHANT - A device and method for measuring concentration of etchant, the device comprises a concentration measuring mechanism and an acid mist elimination mechanism connected with the concentration measuring mechanism, the acid mist elimination mechanism is configured to eliminate acid mist inside the concentration measuring mechanism, and the concentration measuring mechanism is configured to receive etchant in real time, measure absorbance of each kind of acid of the etchant in a non-acid mist environment, and calculate concentration of each kind of acid of the etchant according to the absorbance. It can overcome the interference of the acid mist on concentration measurement of the acid of the acid mixture etchant. In this way, the concentration of each kind of acid of the acid mixture etchant can be online measured rapidly and accurately, and the desiccative gas can be recycled, which achieves the effect of resource conservation. | 09-17-2015 |
20150276584 | COLORIMETER MEASUREMENT METHOD AND COLORIMETER FOR IMPLEMENTING THE METHOD - The present application relates to a colorimeter measurement method and a colorimeter for implementing the method. The method includes the following steps: placing a measured sample on a sample platform; shooting a current image of the sample; determining an intersection angle θ between the sample and a moving direction of the sample platform; adjusting a position of a scanning light spot of a colorimeter according to the angle θ, so that the sample coincides with the moving direction of the sample platform; using the colorimeter to scan the measured sample. By implementing the colorimeter measurement method and the colorimeter of the present application, the sample can be placed optionally when it is measured. Specially, when a design value of a measured sample is approximately equal to a size of the measuring light spot, much time can be saved and manpower waste is avoided. | 10-01-2015 |
20150285723 | Viscosity Measurement Thermostatic Waterbath Device - A viscosity measurement thermostatic waterbath device includes an outer container, an inner container embedded in the outer container's interior, and an interlayer set up between the outer container and the inner container. A circular cavity is formed between the interlayer and the outer container. By a interlayer set between inner and outer containers, the viscosity measurement thermostatic waterbath device provided in the present invention selects inner containers with different diameters according to different samples to be tested, in order to save testing materials and reduces test cost; moreover, by guaranteeing tightness of circular cavities, it lowers tightness requirement of the joint between inner and outer containers, simplifies joint component's structure, in order to make it easier to replace inner containers and reduce test cost. | 10-08-2015 |
Patent application number | Description | Published |
20130045390 | Base Film of Modified Polyvinyl Alcohol and Its Preparation Method and Polarizer - The present invention provides a base film of modified polyvinyl alcohol as well as a method for preparing the base film of modified polyvinyl alcohol and a polarizer made from the base film. The method includes steps of: (1) executing surface graft modification of nano-silicon dioxides with fluorinated silane to obtain modified nano-silicon dioxide powders; (2) adding the modified nano-silicon dioxide powders obtained from the step (1) to an aqueous solution of polyvinyl alcohol polymers, in order to prepare a composite solution of polyvinyl alcohol polymers; and (3) pouring the composite solution of polyvinyl alcohol polymers prepared from the step (2) onto a surface of a casting substrate to obtain a base film of modified polyvinyl alcohol (PVA). The present invention enhances the heat and humidity resistances and the stability of the PVA base film, and improves its mechanical performance and sticking-resistance. | 02-21-2013 |
20140045271 | Potentiometric Titration Method for Measuring Concentration of Acid Mixture of Aluminum Etchant - The present invention provides a potentiometric titration method for measuring concentration of acid mixture of aluminum etchant, which prepares identified potassium hydroxide-ethanol solution or sodium hydroxide-ethanol solution as a titrant and uses a monohydric alcohol and a diol as an anhydrous medium for the acid mixture of aluminum etchant to carry out titration of the acid mixture of aluminum etchant so as to realize measurement of concentration of each acid contained in the acid mixture of aluminum etchant through a one-stage process of potentiometric titration thereby reducing the complication of operation of inspection and uncertainty of inspection result and achieving the purposes of carrying out inspections with high precision and high performance. The method can efficiently and accurately measure the concentrations of nitric acid, phosphoric acid, and acetic acid contained in the acid mixture of aluminum etchant. | 02-13-2014 |
20140326279 | CLEANING EQUIPMENT OF SAMPLE BOTTLE FOR CHRIMATOGRAPHY ANALYSIS AND CLEANING METHOD THEREOF - A cleaning equipment of sample bottle for chromatography analysis comprising: a base; a support frame vertically fixed to the base; a horizontal column having two ends, wherein one of the ends is disposed at the support frame through an adjustment knob; a rotary drive device fixed to the other end of the horizontal columns; a rotation disk which can rotate through driving of the rotary drive device, and a side edge of the rotation disk provides with multiple placing holes for receiving and fixing sample bottles; a cleaning agent recycling tank disposed below the rotation disk, wherein a side wall of it provides with an ejector pipe connected with a water pump; and a control unit for controlling on/off and rotation speed of the rotary drive device, and on/off of the water pump. The invention also provides a cleaning method of sample bottle for chromatography analysis. | 11-06-2014 |
20150140675 | POTENTIOMETRIC TITRATION METHOD OF A MIXED ACID SOLUTION - The present invention provides a potentiometric titration method of calculating a content of each acid in a mixed acid solution. The potentiometric titration method includes steps as follows. Step 1, an alkali-alcohol solution of a concentration in 0.1˜0.2 mol/L is prepared and titrated with a basis reagent. Step 2, a first solvent and a second solvent are added into and stirred with a mixed acid solution consisted of nitric acid, phosphoric acid and acetic acid to form a mixed system, and the mixed system is titrated with the alkali-alcohol solution to obtain three equivalence points of the nitric acid, phosphoric acid and acetic acid in the mixed system. Step 3, a concentration of each acid in the mixed system is measured with the three equivalence points obtained in Step 2. According to the present invention, the content of each acid in the mixed acid solution can be rapidly and precisely measured. | 05-21-2015 |
Patent application number | Description | Published |
20140113578 | AMPLIFIERS WITH NOISE SPLITTING - Amplifiers with noise splitting to improve noise figure are disclosed. In an exemplary design, an apparatus (e.g., a wireless device, an integrated circuit, etc.) includes a plurality of amplifier circuits and at least one interconnection circuit. The amplifier circuits receive an input radio frequency (RF) signal. The interconnection circuit(s) are coupled between the plurality of amplifier circuits. Each interconnection circuit is closed to short the outputs or internal nodes of two amplifier circuits coupled to that interconnection circuit. The plurality of amplifier circuits may include a plurality of gain circuits coupled to a plurality of current buffers, one gain circuit and one current buffer for each amplifier circuit. Each amplifier circuit provides an output current, which may include a portion of the current from each of the plurality of gain circuits when the plurality of amplifier circuits are enabled. | 04-24-2014 |
20140300417 | AMPLIFIERS WITH BOOSTED OR DEBOOSTED SOURCE DEGENERATION INDUCTANCE - Amplifiers with boosted or deboosted source degeneration inductance are disclosed. In an exemplary design, an apparatus includes an amplifier circuit and a feedback circuit. The amplifier circuit receives an input signal and provides an output signal and includes a source degeneration inductor. The feedback circuit is coupled between a node of the amplifier circuit and the source degeneration inductor. The feedback circuit provides feedback to vary an input impedance of an amplifier including the amplifier circuit and the feedback circuit. The feedback circuit may be programmable and may be enabled to provide feedback or disabled to provide no feedback. Alternatively, the feedback circuit may always be enabled to provide feedback. In either case, the feedback circuit may have a variable gain to provide a variable input impedance for the amplifier. | 10-09-2014 |
20150200690 | INTER CARRIER-AGGREGATION ISOLATION IN A RECEIVER - A device includes a first amplifier circuit coupled to a first transformer and a second transformer, the first transformer selectively coupled to a first shared power distribution network through a first switch, the second transformer selectively coupled to a second shared power distribution network through a second switch. | 07-16-2015 |
20150280651 | SPURIOUS SIGNAL MITIGATION FOR CARRIER AGGREGATION AMPLIFIER - A device includes an amplifier circuit comprising a plurality of amplification paths, and at least one switchable bypass capacitance coupled to an associated shared power distribution network, the at least one switchable bypass capacitance and at least one of the plurality of amplification paths responsive to a control signal configured to selectively ground the at least one switchable bypass capacitance and selectively enable the at least one of the amplification paths based on a selected operating mode. | 10-01-2015 |
20150280661 | SINGLE-INPUT MULTIPLE-OUTPUT AMPLIFIERS WITH SIMULTANEOUS MULTIPLE GAIN MODES - A device includes at least one first amplifier circuit configurable to receive and amplify an input radio frequency (RF) signal having a first carrier at a first input signal level and provide a first amplified RF signal, and at least one second amplifier circuit configurable to receive and amplify the input RF signal having a second carrier at a second input signal level and provide a second amplified RF signal, the at least one first amplifier circuit having a first input impedance, the at least one second amplifier circuit having a second input impedance. | 10-01-2015 |
20150341859 | MULTI-STAGE AMPLIFIER WITH RC NETWORK - An apparatus includes a first amplifier stage configured to amplify a first carrier signal. The apparatus includes a second amplifier stage configured to amplify a second carrier signal. A resistive-capacitive (RC) network is coupled to the first amplifier stage and to the second amplifier stage. The RC network includes a resistive element coupled to a capacitive element. | 11-26-2015 |