Carr, GB
Andrew Carr, Little Chesterford GB
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20110112089 | Cysteine Protease Inhibitors - A compound of the formula II | 05-12-2011 |
Andrew Carr, Cambridge GB
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20150344456 | NICOTINE SALTS, CO-CRYSTALS, AND SALT CO-CRYSTAL COMPLEXES - The invention provides certain nicotine salts, co-crystals, and salt co-crystals and provides novel polymorphic forms of certain nicotine salts. In particular, nicotine salts with mucic acid, 3,5-dihydroxybenzoic acid, and 2,3-dihydroxybenzoic acid, and crystalline polymorphic forms of nicotine 4-acetamidobenzoate, nicotine gentisate, and nicotine 1-hydroxy-2-naphthoate are described. The invention further provides methods of preparation and characterization of such nicotine salts, co-crystals, and salt co-crystals and polymorphic forms thereof. In addition, tobacco products, including smoking articles, smokeless tobacco products, and electronic smoking articles comprising nicotine salts, co-crystals, and/or salt co-crystals are also provided. | 12-03-2015 |
Andrew Carr, Essex GB
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20080234260 | Cysteine Protease inhibitors - A compound of the formula II | 09-25-2008 |
Andrew David Carr, Great Chesterford GB
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20130102592 | OXAZOLE TYROSINE KINASE INHIBITORS - The invention provides a compound which is an amide of the formula (1), or a salt, solvate, N-oxide or tautomer thereof; wherein: a is 0 or 1; b is 0 or 1: provided that the sum of a and b is 0 or 1; T is O or NH Ar | 04-25-2013 |
20140275041 | OXAZOLE TYROSINE KINASE INHIBITORS - The invention provides a compound which is an amide of the formula (1), or a salt, solvate, N-oxide or tautomer thereof; wherein: a is 0 or 1; b is 0 or 1: provided that the sum of a and b is 0 or 1; T is O or NH Ar | 09-18-2014 |
20150057282 | OXAZOLE TYROSINE KINASE INHIBITORS - The invention provides a compound which is an amide of the formula (1), or a salt, solvate, N-oxide or tautomer thereof; wherein: a is 0 or 1; b is 0 or 1: provided that the sum of a and b is 0 or 1; T is O or NH Ar | 02-26-2015 |
Andrew David Carr, Cambridge GB
Patent application number | Description | Published |
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20100298301 | OXAZOLE TYROSINE KINASE INHIBITORS - The invention provides a compound which is an amide of the formula (1), or a salt, solvate, N-oxide or tautomer thereof; wherein: a is 0 or 1; b is 0 or 1: provided that the sum of a and b is 0 or 1; T is O or NH Ar | 11-25-2010 |
20110014271 | Substituted Aniline Derivatives - The present invention relates to novel aniline derivatives and their use in therapy, in particular their use in the treatment of fungal infections. | 01-20-2011 |
20120029188 | Substituted Aniline Derivatives - The present invention relates to novel aniline derivatives and their use in therapy, in particular their use in the treatment of fungal infections. | 02-02-2012 |
Beverley Jane Carr, Royston GB
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20110065697 | 2-OXY-BENZOXAZINONE DERIVATIVES FOR THE TREATMENT OF OBESITY - The use of a compound comprising formula (I): | 03-17-2011 |
Brendan Mark Carr, Halstead GB
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20080228420 | Web Marking Systems and Methods - Apparatus for and a method of marking a web | 09-18-2008 |
Christopher Carr, Abingdon GB
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20130117978 | REDUCING SHRINKAGE OF WOOL AND WOOL BLEND FABRICS DUE TO FELTING - A method of treating wool in the form of a fibre, yarn, sliver, fabric or garment. A polymer coating is applied by plasma polymerisation to prevent shrinkage due to felting due to laundering. The method may include a pre-treatment step, for example application of a continuous plasma of inert gas, application of nano particles to the fibre surface or coating the fibre surface with a polymer. | 05-16-2013 |
Conor Carr, Tynemouth (north Tyneside) GB
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20130335235 | TELEMETRY MONITORING SYSTEM AND A DATA RECOVERY METHOD FOR A TELEMETRY MONITORING SYSTEM - There is disclosed a telemetry monitoring system including a central monitoring unit configured to display data regarding one or more portable devices, each associated with the breathing apparatus of a user. The system further includes removable data storage connected to the central monitoring unit and configured to store system status data of the central monitoring unit as recovery data, the system status data defining an operational status of the central monitoring unit. In the event of a failure of the telemetry monitoring system, the telemetry monitoring system can be recovered by restoring the recovery data to the central monitoring unit or a replacement central monitoring unit from the removable data storage. | 12-19-2013 |
Conor Carr, North Tyneside GB
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20140068063 | TELEMETRY MONITORING APPARATUS - There is disclosed a telemetry monitoring apparatus for remotely monitoring a plurality of users, such as firefighters, working in a hazardous environment. The apparatus comprises a plurality of portable devices, each arranged to be associated with breathing apparatus worn by a user, and at least one central monitoring station onto which portable devices can be logged on and monitored. The portable devices are arranged to transmit a logon message including an identifier identifying either the user or the portable device. | 03-06-2014 |
David J. Carr, Winchester GB
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20150261619 | CASCADE ORDERING - A method of handling multiple served backup processes comprising creating a cascade of target storage volumes from a plurality of target storage volumes by inserting each most recent target storage volumes between a last added target storage volume and a source storage volume, the most recent target storage volumes each having a copy rate faster than the last added target storage volume, such that each added target storage volume has a faster copy rate than an immediately prior added target storage volume, and a most recent target storage volume added to the cascade of target storage volumes has a fastest copy rate; and receiving one or more instructions initiating a plurality of served backup processes from the source storage volume to a plurality of target storage volumes. | 09-17-2015 |
David J. Carr, Winchster GB
Patent application number | Description | Published |
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20110289291 | CASCADE ORDERING - A system and a method of handling multiple backup processes have been provided. The method comprises receiving one or more instructions initiating a plurality of backup processes from a single source storage volume to a plurality of target storage volumes, adding each target storage volume to a cascade of target storage volumes from the source storage volume, the target storage volumes added to the cascade in an order inversely proportional to the copy rate of the respective backup process, and starting each backup process in turn, the backup processes started in an order from the most recent target storage volume added to cascade to the first target storage volume added to cascade. | 11-24-2011 |
20120260053 | CASCADE ORDERING - A method comprises receiving one or more instructions initiating a plurality of backup processes from a single source storage volume to a plurality of target storage volumes, adding each target storage volume to a cascade of target storage volumes from the source storage volume, the target storage volumes added to the cascade in an order inversely proportional to the copy rate of the respective backup process, and starting each backup process in turn, the backup processes started in an order from the most recent target storage volume added to cascade to the first target storage volume added to cascade. | 10-11-2012 |
20150261618 | CASCADE ORDERING - A method comprises creating a cascade of target storage volumes from a plurality of target storage volumes by inserting each most recent target storage volumes between a last added target storage volume and a source storage volume, the most recent target storage volumes each having a copy rate faster than the last added target storage volume, such that each added target storage volume has a faster copy rate than an immediately prior added target storage volume, and a most recent target storage volume added to the cascade of target storage volumes has a fastest copy rate; and receiving one or more instructions initiating a plurality of backup processes from the source storage volume to a plurality of target storage volumes. | 09-17-2015 |
David John Carr, Southampton GB
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20090006763 | Arrangement And Method For Update Of Configuration Cache Data - An arrangement and method for update of configuration cache data in a disk storage subsystem in which a cache memory ( | 01-01-2009 |
20110208938 | VIRTUALIZATION ENGINE AND METHOD, SYSTEM, AND COMPUTER PROGRAM PRODUCT FOR MANAGING THE STORAGE OF DATA - A storage management method for use in a storage area network is provided. The storage area network comprises a plurality of host data processors coupled to a virtualization engine, which is coupled to a plurality of physical storage media. Each physical storage media is assigned a tier level. The method comprises storing a threshold storage access value associated with each tier level, presenting virtual disk(s) to a host data processor and receiving I/O requests to the virtual disk from the host data processor. Additionally, metadata is stored which identifies the tier level of the physical storage to which the block corresponds, mappings between the block and blocks of a virtual disk, and an access rate to the data. The access value is periodically compared to at least one threshold rate associated with its tier level. Depending on the result, storage block(s) may be marked for migration to another tier level. | 08-25-2011 |
David Russell Carr, Hampshire GB
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20080251575 | SYSTEM FOR CAPTURING AND MANAGING PERSONALIZED VIDEO IMAGES OVER AN IP-BASED CONTROL AND DATA LOCAL AREA NETWORK - A system is deployed at a theme park for capturing and managing personalized video images, e.g., for creating personalized video products for patrons at the theme park. The system includes an RFID system to track patron movements around the park, a camera system to capture video images at designated locations around the park, a computer-based video content collection system to collect and store personalized video clips of patrons, and a video product (e.g., DVD) creation and point of sale system to create the end product for sale to the patron. | 10-16-2008 |
David William Carr, Newcastle Upon Tyne GB
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20110049324 | SLIDE ASSEMBLY FOR PARKING A VEHICLE - A vehicle slide assembly ( | 03-03-2011 |
Francis Carr, Aberdeenshire GB
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20090191187 | ANTIBODIES AGAINST INTERLEUKIN-1 RECEPTOR AND USES THEREOF - The present invention relates to antibodies against interleukin-1 receptor (IL-1R), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. The antibodies of the present invention are particularly useful for treating a variety of inflammatory diseases including, but not limited to, rheumatoid arthritis. | 07-30-2009 |
Francis Joseph Carr, Aberdeenshire GB
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20090175923 | HUMANIZED ANTI-AMYLOID BETA ANTIBODIES - Humanized anti-Aβ antibodies derived from a murine antibody directed to a N-terminal epitope of Aβ are described. The humanized antibodies have reduced or no human T cell epitopes and bind Aβ with an affinity similar to that of the murine antibody. | 07-09-2009 |
20090196880 | Cancer treatment using humanized antibodies that bind to EphB4 - In certain embodiments, this application provides humanized antibodies that bind to the EphB4 protein as well as uses of the antibodies for therapeutic purposes. | 08-06-2009 |
20110177076 | HUMANIZED ANTI-AMYLOID BETA ANTIBODIES - Humanized anti-Aβ antibodies derived from a murine antibody directed to a N-terminal epitope of Aβ are described. The humanized antibodies have reduced or no human T cell epitopes and bind Aβ with an affinity similar to that of the murine antibody. | 07-21-2011 |
20120183545 | CD20-Binding Polypeptide Compositions and Methods - A method of treating an autoimmune disease comprising administering to a patient a therapeutically effective amount of a CD20-binding polypeptide composition comprising a combination of a modified heavy chain variable region polypeptide and a modified light chain variable region polypeptide. The combination can be (a) a modified 2B8 antibody heavy chain variable region polypeptide of SEQ ID NO: 48; and a modified 2B8 antibody light chain variable region polypeptide of SEQ ID NO: 49; or (b) a modified Leu16 antibody heavy chain variable region polypeptide of SEQ ID NO: 50; and a modified Leu16 antibody light chain variable region polypeptide of SEQ ID NO: 51. | 07-19-2012 |
20160106819 | RIBOTOXIN MOLECULES DERIVED FROM SARCIN AND OTHER RELATED FUNGAL RIBOTOXINS - The present application relates to modified T cell epitopes derived from fungal ribotoxins, including a-sarcin, clavin, gigantin, mitogillin, and restrictocin, as well as modified ribotoxin molecules comprising one or more of the modified epitopes. The modified ribotoxin molecules inhibit protein synthesis, like the wild type ribotoxins, but exhibit reduced immunogenicity as compared to the corresponding wild type ribotoxin. Another aspect relates to a fusion protein which comprises a modified ribotoxin fused or conjugated or otherwise linked to a targeting molecule that is effective for binding a target of interest. Another aspect relates to the use of the modified ribotoxin or fusion protein for treating or managing a disease or condition. | 04-21-2016 |
Francis Joseph Carr, Balmedie Aberdeenshire GB
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20140105914 | HUMANISED ANTI CTLA-4 ANTIBODIES - The invention provides an anti-CTLA4 antibody which inhibits the binding of CTLA4 to human B7, in particular, it inhibits binding of CTLA4 to human B7.1 and/or human B7.2. Specific antibodies are provided with specific variable region sequences as well as compositions comprising such antibodies for use in treating disease. | 04-17-2014 |
Francis Joseph Carr, Aberdeen GB
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20130136735 | HUMANIZED ANTIBODIES TO iNKT - Methods of treatment to suppress an immune response are provided. The method comprises administering to a subject in need of treatment a naked blocking antibody that binds selectively iNKT cells in an amount effective to suppress the subject's iNKT cell function. Compositions comprising, an isolated, humanized antibody that binds selectively iNKT cells are also provided. | 05-30-2013 |
20140161870 | Antibody Specific for CD22 and Methods of Use Thereof - The present disclosure provides antibodies specific for an epitope present on CD22. The antibodies are useful in various treatment, diagnostic, and monitoring applications, which are also provided. | 06-12-2014 |
20160031992 | ANTI-ALPHA V BETA 6 ANTIBODIES AND USES THEREOF - Humanized antibodies and antibody fragments thereof that bind to αvβ6 are disclosed. Also disclosed are methods of using these antibodies and antibody fragments to treat or prevent αvβ6-mediated diseases such as fibrosis and cancer. | 02-04-2016 |
Francis Joseph Carr, Balmedie GB
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20130121983 | Modified Forms of Pseudomonas Exotoxin A - exotoxin A or “PE” is a 66 kD, highly potent, cytotoxic protein secreted by the bacterium | 05-16-2013 |
20140065168 | ANTI-KIT ANTIBODIES AND USES THEREOF - Provided herein, in one aspect, are antibodies that immunospecifically bind to a human KIT antigen comprising the fourth and/or fifth extracellular Ig-like domains (that is, D4 and/or D5 domains), polynucleotides comprising nucleotide sequences encoding such antibodies, and expression vectors and host cells for producing such antibodies. The antibodies can inhibit KIT activity, such as ligand-induced receptor phosphorylation. Also provided herein are kits and pharmaceutical compositions comprising antibodies that specifically bind to a KIT antigen, as well as methods of treating or managing a KIT-associated disorder or disease and methods of diagnosing a KIT-associated disorder or disease using the antibodies described herein. | 03-06-2014 |
20140127236 | HUMANISED ANTI-CD52 ANTIBODIES - The present invention relates to novel humanised antibodies against human CD52 and their use in methods of treating or preventing human diseases. | 05-08-2014 |
20150125878 | ANTIBODIES AGAINST CD106 (VCAM-1) - The invention provides an antibody or fragment thereof that specifically binds to human endothelial vascular cell adhesion molecule-1 (VCAM-1), wherein the antibody or fragment thereof binds to the extracellular domain of VCAM-1, and wherein the antibody or fragment thereof binds to VCAM-1 when expressed on endothelial cells, wherein the antibody or fragment thereof is a human or humanized antibody, or fragment thereof. | 05-07-2015 |
20150175699 | HUMANIZED ANTIBODIES TO CLUSTER OF DIFFERENTIATION 3 (CD3) - Humanized monoclonal antibodies (mAbs) or fragments thereof, to human Cluster of Differentiation 3 (CD3), which confer improved immune stimulation and stability, are disclosed. Pharmaceutical compositions comprising said mAbs and methods of treatment and optionally also prevention of diseases and disorders, such as autoimmune disorders, infectious diseases, and transplant rejection, that are susceptible to amelioration by binding to CD3, are also disclosed. | 06-25-2015 |
20160108377 | MODIFIED FORMS OF PSEUDOMONAS EXOTOXIN A - exotoxin A or “PE” is a 66 kD, highly potent, cytotoxic protein secreted by the bacterium | 04-21-2016 |
Francis Joseph Carr, Balmedie, Aberdeen GB
Patent application number | Description | Published |
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20150291941 | MODIFIED FORMS OF PSEUDOMONAS EXOTOXIN A - exotoxin A or “PE” is a 66 kD, highly potent, cytotoxic protein secreted by the bacterium | 10-15-2015 |
Francis Joseph Carr, Cambridge GB
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20100017370 | T CELL EPITOPE DATABASES - The invention relates to databases of T cell epitopes, especially helper T cell epitopes, for rapid interrogation of protein sequences for the presence of T cell epitopes. The invention includes full or partial databases and data structures of T cell epitopes including epitopes identified especially by ex vivo T cell assays with test peptides and includes T cell epitopes identified by extrapolation of data from test peptides. The present invention also includes high throughput methods for determining the T cell epitope activity of peptides for subsequent inclusion in databases and data structures including methods where subsets of T cell especially regulatory T cells are removed or inhibited from T cell assays in order to maximize the sensitivity of detection of T cell epitope activity. | 01-21-2010 |
Francls Joseph Carr, Aberdeen GB
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20160115223 | POLYPEPTIDES COMPRISING A MODIFIED BACTERIOPHAGE G3P AMINO ACID SEQUENCE WITH REDUCED IMMUNOGENICITY - The invention relates to polypeptides that comprise a portion of filamentous bacteriophage gene 3 protein (g3p) sufficient to bind to and/or disaggregate amyloid, e.g., the N1-N2 portion of g3p and mutants and fragments thereof wherein that g3p amino acid sequence has been modified through amino acid substitution to be substantially less immunogenic than the corresponding wild-type g3p amino acid sequence when used in vivo. The polypeptides of the invention retain their ability bind to and/or disaggregate amyloid. The invention relates furthermore to the use of these variant g3p-polypeptides in the treatment and/or prevention of diseases associated with misfolding or aggregation of amyloid. | 04-28-2016 |
Frank J. Carr, Aberdeenshire GB
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20100203042 | RECOMBINANT ANTI-VLA4 ANTIBODY MOLECULES - The present invention disclosed recombinant anti-VLA-4 antibody molecules, including humanized recombinant anti-VLA-4 antibody molecules. These antibodies are useful in the treatment of specific and non-specific inflammation, including asthma and inflammatory bowel disease. In addition, the humanized recombinant anti-VLA-4 antibodies disclosed can be useful in methods of diagnosing and localizing sites of inflammation. | 08-12-2010 |
20120022236 | Recombinant Anti-VLA4 Antibody Molecules - The present invention disclosed recombinant anti-VLA-4 antibody molecules, including humanized recombinant anti-VLA-4 antibody molecules. These antibodies are useful in the treatment of specific and non-specific inflammation, including asthma and inflammatory bowel disease. In addition, the humanized recombinant anti-VLA-4 antibodies disclosed can be useful in methods of diagnosing and localizing sites of inflammation. | 01-26-2012 |
Gary Carr, Hampshire GB
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20120309536 | SHAPE TRACE GESTURING - Gestures of a computer user are observed with a depth camera. A trace gesture of the computer user is identified and an action performable within an interactive interface is selected based on the shape of the trace gesture. | 12-06-2012 |
Graham Carr, Liverpool GB
Gregory Carr, Macclesfield GB
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20090312556 | N-(2-AMINIPHENYL)-4-(5-((ETHYLAMINO)METHYL)-1,2-THIAZOL-2-YL) BENZAMIDE AND N-(2-AMINOPHENYL)-4-(5-((ISOPROPYLAMINO)METHYL)-1,2-THIAZOL-2-YL) BENZAMIDE AS HDAC INHIBITORS - The invention concerns novel benzamide compounds of Formula (I): wherein R wherein is ethyl or isopropyl; or a pharmaceutically acceptable salt or pro-drug form thereof. The invention also concerns processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours or other proliferative conditions, which are sensitive to the inhibition of histone deacetylase (HDAC). | 12-17-2009 |
Gregory Richard Carr, Cheshire GB
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20100120798 | SUBSTITUTED PIPERIDINES CONTAINING A HETEROARYLAMIDE OR HETEROARYLPHENYL MOIETY - The invention provides compounds of the formula (I) having PKA and PKB kinase inhibiting compounds of the formula (I): GP 1 J T 2 J N 4 R N H (I) or salts, solvates, tautomers or N-oxides thereof, wherein (1) GP is a group GP1: HET 2a a Q G (HNCO)f 7 (R)x N * (GP1) (2) GP is a group GP2: 10 (R)r O 2a a QG (CH2)w N V H N * (GP2) wherein HET is a monocyclic or bicyclic heterocyclic group containing up to 4 heteroatom ring members; the ring V is a monocyclic or bicyclic heteroaryl group of 5 to 10 ring members; and J1, J2, R4, R7, R10, Q2a, Ga, x, w and f are as defined in the claims | 05-13-2010 |
20100267699 | CHEMICAL COMPOUNDS - 643 - The invention concerns bicyclic compounds of Formula I | 10-21-2010 |
20130203714 | CHEMICAL COMPOUNDS - 643 - The invention concerns bicyclic compounds of Formula I | 08-08-2013 |
Henry David Lambton Carr, Huddersfield GB
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20100143099 | TURBOCHARGER - A turbocharger comprises a turbine wheel ( | 06-10-2010 |
20110038714 | VARIABLE GEOMETRY TURBINE - A variable geometry turbine of the kind used in a turbocharger has a variable geometry element such as a nozzle ring that is operated by an actuator. The actuator comprises a motor which drives a cross-shaft in rotation. The cross-shaft in turn drives a pair of guide rods on which the nozzle ring is supported in translation so as to move the nozzle ring and control the width of the inlet passage of the turbine. The cross-shaft and guide rods are drivingly engaged by a rack and pinion or thread or another toothed or threaded formation suitable for converting rotational movement into translational movement. The cross-shaft can be located in close proximity to the guide rods and the output of the motor shaft so as to provide a compact package. Moreover, the torque required to resist movement of the nozzle ring in operation is much reduced in comparison to existing designs. | 02-17-2011 |
Hollie Carr, Southampton GB
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20090125597 | EMAIL ANNOTATION - A method of creating an annotation to an email. The method includes: receiving an email; receiving a predefined user input; creating an annotation in response to the predefined user input, the annotation linked to the email; receiving a further user input; and defining a permission for the annotation according to the further user input, the permission defining user access to the annotation. When transmitting a second email as a response to the received email, the second email is linked to the annotation. The method further includes displaying at least a part of the annotation linked to the received email, for example when a user hovers over the email. The structure of the annotations allows the associating of the annotation with one or more further annotations. | 05-14-2009 |
James Lindsay Carr, Greater London GB
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20090247519 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE - The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain amino-ethyl-amino-aryl (AEAA) compounds which, inter alia, inhibit protein kinase D (PKD) (e.g., PKD1, PKD2, PKD3). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit PKD, and in the treatment of diseases and conditions that are mediated by PKD, that are ameliorated by the inhibition of PKD, etc., including proliferative conditions such as cancer, etc. | 10-01-2009 |
John Christopher Carr, Woking GB
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20120083680 | NEEDLE TIP AND NEEDLE PROBE - A monopolar needle probe for measurement of electrical activity in a patient. The needle probe has a nonconductive sheath and a conductive needle within the nonconductive sheath. The conductive needle has a longitudinal axis. An end of the needle is exposed from the nonconductive sheath and the end defines a plurality of substantially planar and symmetrical surfaces. | 04-05-2012 |
John Christopher Carr, Surrey GB
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20130237795 | PERFORMANCE CONCENTRIC ELECTROMYOGRAPHY NEEDLE - An electromyography needle electrode having an inner core and an outer elongated cannula surrounding the inner core, wherein the inner core includes tungsten. The inner core may comprise at least 99.95 percent tungsten. The outer elongated cannula forms an outer conductive electrode and the inner core forms an inner conductive electrode. At least one insulating layer may be formed between the outer elongated cannula and the inner core. The impedance of the anode and cathode may be matched more closely. | 09-12-2013 |
John Peter Carr, Dunfermline GB
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20100072456 | OPTO-ELECTRONIC READ HEAD - A read head for a scale reading apparatus, the head including a light source and an array of photodetector elements, wherein said light source and array of photodetector elements are fabricated in a lattice matched semiconductor compound. | 03-25-2010 |
Joshua M. Carr, Southampton GB
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20150135123 | CURSOR-BASED CHARACTER INPUT INTERFACE - A cursor-based character input interface inputs a character selected by a cursor. A character prediction unit is adapted to predict one or more next characters based on a current input character, wherein the input interface is adapted to present the one or more predicted next characters as a supplementary interface in proximity to the current input character, and wherein the one or more predicted next characters of the supplementary interface are selectable by the cursor. | 05-14-2015 |
Leslie Carr, Southampton GB
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20140280639 | Methods, Systems, and Devices for Analyzing Social Media Content - A system for analyzing social media content and for determining the influence types of different social media members is disclosed. The system categorizes users according to their influence on the social media conversation and displays information related to this categorization in schematic form. The popularity of a particular topic can be analyzed to determine when the topic resonates and becomes more popular within the social network. In some embodiments, the categorization of the users and schematic display of information can be conducted in real-time. | 09-18-2014 |
Matthew Carr, Cambridge GB
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20110074122 | TOOL-LESS BLADE CLAMPING APPARATUS FOR A RECIPROCATING TOOL - Several preferred embodiments are disclosed for a tool-less blade clamping apparatus for a reciprocating tool of the type which has a reciprocating plunger which has a tool attachment receiving slot for receiving a tool attachment of the type that has a shank portion. The clamping apparatus has an unclamped position and a clamped position. In the unclamped position, a tool attachment can be easily inserted and when it is in its clamped position, the tool attachment is securely retained. The preferred embodiments have at least one spring biasing the apparatus toward the clamped position, a releasable retaining mechanism for holding the apparatus in its unclamped position after being placed in that position. When the blade shank portion is inserted into the slot a predetermined distance, the shoulders of the shank portion release the retaining mechanism to move it to its clamped position. When a blade is to be removed, the clamping apparatus needs only to be moved to its unclamped position by manually rotating the outer sleeve or collar, and the blade is normally ejected from the mechanism by contact with the blade shoulders as it reaches its unclamped position. | 03-31-2011 |
20120216386 | MICRODIALYSIS PROBE AND METHOD FOR THE PRODUCTION THEREOF - A microdialysis probe including a probe body, a supply line and a discharge line for a perfusion solution and a dialysis membrane, wherein a probe needle for introduction into a tissue is provided by a generally elongate frame. The frame has at least one recess at least partially open for receiving at least a portion of the supply and discharge lines. The invention encompasses a method for making such a probe, wherein the method includes arranging a dialysis membrane on a shaping device, shaping the dialysis membrane in a selected shape, applying an adhesive agent to the dialysis membrane to keep the membrane in the selected shape, and separating the dialysis membrane and the shaping devices after the adhesive agent has been applied. | 08-30-2012 |
20130193653 | Tool-Less Blade Clamping Apparatus for a Reciprocating Tool - Several preferred embodiments are disclosed for a tool-less blade clamping apparatus for a reciprocating tool of the type which has a reciprocating plunger which has a tool attachment receiving slot for receiving a tool attachment of the type that has a shank portion. The clamping apparatus has an unclamped position and a clamped position. In the unclamped position, a tool attachment can be easily inserted and when it is in its clamped position, the tool attachment is securely retained. The preferred embodiments have at least one spring biasing the apparatus toward the clamped position, a releasable retaining mechanism for holding the apparatus in its unclamped position after being placed in that position. When the blade shank portion is inserted into the slot a predetermined distance, the shoulders of the shank portion release the retaining mechanism to move it to its clamped position. When a blade is to be removed, the clamping apparatus needs only to be moved to its unclamped position by manually rotating the outer sleeve or collar, and the blade is normally ejected from the mechanism by contact with the blade shoulders as it reaches its unclamped position. | 08-01-2013 |
Matthew John Carr, Cambridge GB
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20080295698 | Drink Machine - The invention provides a thermally-actuated pump for use in a hot drink maker The pump comprises a thermal actuator ( | 12-04-2008 |
Matthew John Carr, Cambridgeshire GB
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20100168672 | PORTABLE INFUSION PUMP OF THE SKIN PATCH TYPE WITH SPIRAL COLLAPSIBLE RESERVOIR - An ambulatory pump comprising a reservoir ( | 07-01-2010 |
Paul Carr, Yorkshire GB
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20100208260 | DIRECT DETECTION OF MARKERS IN PRESSURIZED HYDROCARBON FLUIDS - This invention generally relates to a method and apparatus for direct detection of one or more markers in pressurized hydrocarbon fluids. The apparatus includes a vessel ( | 08-19-2010 |
20100214373 | AUTHENTICATING A PRODUCT - This invention generally relates to a composition, an apparatus, and a method for authenticating a product. In particular, the invention relates to an ink composition for marking a product with a continuous inkjet printer. The composition includes a visible ink and a UV, visible, and/or IR marker. Marking includes depositing the ink composition on the product with the continuous inkjet printer. A marked product is authenticated with a hand-held apparatus that activates the marker in the mark with UV radiation. Activation of the marker in the mark changes the absorbance/reflectance of visible radiation by the mark without changing the visual appearance of the mark. Authenticity of the product is assessed by a change in absorbance or reflectance of visible radiation by the mark after activation of the mark. | 08-26-2010 |
Paul David Carr, Greater Manchester GB
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20110081348 | FUNGAL SIGNALLING AND METABOLIC ENZYMES - Method of identifying an anti-fungal agent which targets as an essential protein or gene of a fungus comprising contacting a candidate substance with (i) a protein which comprises the sequence shown by SEQ ID NOS: 3, 6, 9, 12, 15, 18, 21, 24, 27, 30, 33, 36, 39, 42, 45, 48, 50, 53, 56, 59, 61 or 63, or (ii) a protein which has 60% identity with (i), or (iii) a protein comprising a fragment of (i) or (ii) which fragment has a length of at least 50 amino acids, or (iv) a polynucleotide that comprises a sequence which encodes (i), (ii) or (iii), or (v) a polynucleotide comprising a sequence which has at least 70% identity with the coding sequence of (iv), and determining whether the candidate substance binds or modulates (i), (ii), (iii), (iv), or (v), wherein binding or modulation of (i), (ii), (iii), (iv), or (v) indicates that the candidate substance is an anti-fungal agent. | 04-07-2011 |
Paul L. Carr, Harrogate GB
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20080268334 | Extruded battery components and manufacturing process - The invention provides an apparatus and method for producing multilayer laminates of polymeric electrolyte material incorporating one of more electrode layers. The apparatus ( | 10-30-2008 |
Reuben Carr, Edinburgh GB
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20110270054 | ASSAY FOR POSITIONING A FEEDING TUBE AND METHOD THEREOF - The present invention discloses a bedside or point of care assay for properly positioning a feeding tube in the stomach of a patient based on detecting the presence of a hydrolytic enzyme found in the stomach by an ester substrate which can be impregnated on a pH strip. The application of this test reduces the risk of tube misplacement and the resulting harm to the patient that occurs in the event of tube misplacement. | 11-03-2011 |
Robert Carr, Lancashire GB
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20110048421 | CARRYING SYSTEM FOR BREATHING APPARATUS - A carrying system is provided for use with breathing apparatus. The carrying system includes a backplate and a plurality of straps adapted to hold the backplate on the back of a user when the carrying system is worn. The backplate includes at least one plate of a plastics material. The at least one plate having a predetermined shape and the at least one plate being adapted to provide impact protection to a user during use by at least partially absorbing and/or dispersing impact forces, and to deform resiliency in response to external forces imposed by bending and/or twisting of a user during use and return substantially to its predetermined shape when not subjected to an external force. | 03-03-2011 |
Robert Jeffrey Geddes Carr, Wiltshire GB
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20140152978 | Optical Detection and Analysis of Particles - The present invention provides a method of analysing a sample comprising sub-micron particles, comprising determining first information about the size of particles and number of particles in the sample by nanoparticle tracking analysis; determining second information about average particle size of particles in the sample by dynamic light scattering; determining from the first information third information representing the theoretical effect of the detected particles on results obtainable by dynamic light scattering; and adjusting the second information using the third information to produce fourth information representing adjusted information on average particle size. | 06-05-2014 |
Robert Jeffrey Geddes Carr, Salisbury GB
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20080252884 | OPTICAL DETECTION AND ANALYSIS OF PARTICLES - Method and apparatus for the single particle detection of submicron structures such as biological molecules and viruses utilises an optical element ( | 10-16-2008 |
Robin Arthur Ellis Carr, Bassingbourn GB
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20080287399 | Substituted Aminopyridines and Uses Thereof | 11-20-2008 |
20090062282 | Substituted Amino-Pyrimidones and Uses Thereof - This invention relates to novel compounds having the structural formula Ia or formula Ib below: (Ia, Ib), and their pharmaceutically acceptable salts, tautomers or in vivo hydrolysable precursors, compositions and methods of use thereof. These novel compounds provide a treatment or prophylaxis of Aβ related pathologies such as cognitive impairment, Alzheimer Disease, neurodegeneration and dementia. | 03-05-2009 |
20090221579 | Substituted Amino-Compounds and Uses Thereof - This invention relates to novel compounds having the structural formula Ia or formula Ib: Ia Ib and their pharmaceutically acceptable salts, tautomers or in vivo hydrolysable precursors, compositions and methods of use thereof. These novel compounds provide a treatment or prophylaxis of Aβ related pathologies such as cognitive impairment, Alzheimer Disease, neurodegeneration and dementia. | 09-03-2009 |
20110144080 | PYRAZOLE DERIVATIVES AS PROTEIN KINASE MODULATORS - The invention provides compounds of the formula: (I) having protein kinase B inhibiting activity: wherein A is a saturated hydrocarbon linker group containing from 1 to 7 carbon atoms, the linker group having a maximum chain length of 5 atoms extending between R | 06-16-2011 |
20130005702 | PYRAZOLE DERIVATIVES AS PROTEIN KINASE MODULATORS - The invention provides compounds of the formula (I) having protein kinase B inhibiting activity: | 01-03-2013 |
20140271662 | PYRAZOLE DERIVATIVES AS PROTEIN KINASE MODULATORS - The invention provides compounds of the formula (I) having protein kinase B inhibiting activity: | 09-18-2014 |
Shane Allen Carr, Cornwall GB
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20090020064 | PONTOONS - A pontoon structure consisting of two concrete side members with a buoyancy member interposed between them, a plurality of transverse members linking the side members and a deck extending between the side members. | 01-22-2009 |
Simon Carr, Bloxham GB
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20130061762 | Beverage Preparation Machines - A beverage preparation machine of the type which uses pre-packed cartridges of beverage ingredients. The cartridges may be designed so that air becomes entrained so as to produce a desired foam or crema. Air inlets are provided in an outlet nozzle to allow air to enter the beverage preparation machine and so be available for entrainment. Advantageously, the air inlets extend through the sides of the nozzle in an elevated position at a widened portion of the nozzle. This reduces the flow of beverage into and through the air inlets, aiding cleanliness. | 03-14-2013 |
Simon Carr, Banbury GB
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20150017293 | BEVERAGE PREPARATION SYSTEM, A CODED INSERT AND METHODS OF USE THEREOF - A beverage preparation system is provided comprising a beverage preparation machine, a cartridge containing one or more beverage ingredients, and a coded insert. The beverage preparation machine comprises a brew head for receiving the cartridge. The cartridge comprises a primary code configured to provide operating instructions to the beverage preparation machine for delivering a beverage from the cartridge. The coded insert is separate from the cartridge and insertable along with the cartridge into the brew head. The coded insert comprises a secondary code configured to provide alternative operating instructions to the beverage preparation machine for delivering a modified beverage from the cartridge. | 01-15-2015 |
20150297023 | A METHOD OF DISPENSING A BEVERAGE, A BEVERAGE PREPARATION MACHINE, AND A SYSTEM - The present invention provides a method of dispensing a beverage comprising: a) inserting a beverage ingredient tablet ( | 10-22-2015 |
20150313402 | METHOD OF DISPENSING A BEVERAGE, A BEVERAGE PREPARATION MACHINE, AND A SYSTEM - A method of dispensing a beverage comprising: a) inserting a beverage ingredient tablet ( | 11-05-2015 |
20150360854 | CARTRIDGE FOR THE PREPARATION OF BEVERAGES - A cartridge for preparation of a beverage is provided which is sealed prior to use and contains one or more beverage ingredients. The cartridge comprises: | 12-17-2015 |
20150374167 | BEVERAGE PREPARATION MACHINES - The present invention relates to improvements in beverage preparation machines and in particular to a beverage preparation machine of the type which uses pre-packed cartridges of beverage ingredients. The cartridges may be designed so that air becomes entrained so as to produce a desired foam or crema. Air inlets are provided in an outlet nozzle to allow air to enter the beverage preparation machine and so be available for entrainment. Advantageously, the air inlets extend through the sides of the nozzle in an elevated position at a widened portion of the nozzle. This reduces the flow of beverage into and through the air inlets, aiding cleanliness. | 12-31-2015 |
Tony Carr, London GB
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20150121786 | VENTILATION UNITS - A set of ventilation units comprises a first and second ventilation unit, wherein a surface of the first ventilation unit is provided with at least one formation and a surface of the second ventilation unit is provided with at least one co-operating formation. The formation(s) and co-operating formation(s) is/are engageable with one another in a direction substantially perpendicular to said surface of the first ventilation unit and/or said surface of the second ventilation unit. | 05-07-2015 |
Tony Carr, Bedfordshire GB
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20110312021 | METHOD AND APPARATUS FOR THE NON-INVASIVE MONITORING OF GAS EXCHANGE BY BIOLOGICAL MATERIAL - The invention provides an indirect pressure sensing system for non-invasive measurement of primary pressure in a sealed container, which communicates primary pressure changes from within the container, via a flexible diaphragm, to a secondary chamber wherein there is a defined relationship between the primary and secondary pressures, which enables a pressure sensor in the secondary chamber to generate a signal representing primary pressure in the sealed container, but to remain isolated from the contents of the sealed container. The pressure sensor can provide electrical outputs representing the pressure detected, and the outputs are fed to data processing means capable of producing a measurement of primary pressure. The system can have a liquid culture of cellular material (eg. micro organisms, plant tissue cells, animal cells etc) partially filling the container, whereby the metabolism and/or growth of cellular material causes gas exchanges between liquid and headspace, which can result in primary pressure changes. | 12-22-2011 |
20130130300 | METHOD AND APPARATUS FOR THE NON-INVASIVE MONITORING OF GAS EXCHANGE BY BIOLOGICAL MATERIAL - The invention provides an indirect pressure sensing system for non-invasive measurement of primary pressure in a sealed container, which communicates primary pressure changes from within the container, via a flexible diaphragm, to a secondary chamber wherein there is a defined relationship between the primary and secondary pressures, which enables a pressure sensor in the secondary chamber to generate a signal representing primary pressure in the sealed container, but to remain isolated from the contents of the sealed container. The pressure sensor can provide electrical outputs representing the pressure detected, and the outputs are fed to data processing means capable of producing a measurement of primary pressure. The system can have a liquid culture of cellular material (eg. micro organisms, plant tissue cells, animal cells etc) partially filling the container, whereby the metabolism and/or growth of cellular material causes gas exchanges between liquid and headspace, which can result in primary pressure changes. | 05-23-2013 |
William Carr, Swanwick GB
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20110147302 | Oil/Water Separator - An oil/water separator includes an ingress ( | 06-23-2011 |