Patent application number | Description | Published |
20120164673 | PTP1B INHIBITORS - Described herein are agents, including antibodies, antibody fragments, polypeptides and organic small molecules, that bind reversibly inactive PTP1B (designated herein in the alternative as PTP1B-SN or PTP1B-OX) and stabilize it (stabilize PTP1B-OX) in such a manner that they inhibit reactivation of reversibly oxidized, inactive PTP1B by reduction (by reducing agent) and have no substantial direct inhibitory effect on phosphatase activity/PTP1B activity (for example, as detectable in assays in vitro). | 06-28-2012 |
20130029366 | PTP1B INHIBITORS - Described herein are agents, including antibodies, antibody fragments, polypeptides and organic small molecules, that bind reversibly inactive PTP1B (designated herein in the alternative as PTP1B-SN or PTP1B-OX) and stabilize it (stabilize PTP1B-OX) in such a manner that they inhibit reactivation of reversibly oxidized, inactive PTP1B by reduction (by reducing agent) and have no substantial direct inhibitory effect on phosphatase activity/PTP1B activity (for example, as detectable in assays in vitro). | 01-31-2013 |
Patent application number | Description | Published |
20110095117 | Methods, Systems, And Products Involving Sheet Products - A method for forming a tubular sheet product roll includes providing a sheet product roll having a first configuration and a void, centering a rotational axis of the sheet product roll on a longitudinal axis of a first tool, and inserting the first tool into the void of the sheet product roll to define an inner diameter of the void and to form the sheet product roll having a second configuration different from the first configuration. | 04-28-2011 |
20130225381 | METHODS, SYSTEMS AND PRODUCTS INVOLVING SHEET PRODUCTS - A method for forming a tubular sheet product roll includes providing a sheet product roll having a first configuration and a void, centering a rotational axis of the sheet product roll on a longitudinal axis of a first tool, and inserting the first tool into the void of the sheet product roll to define an inner diameter of the void and to form the sheet product roll having a second configuration different from the first configuration. | 08-29-2013 |
20130225382 | METHODS, SYSTEMS AND PRODUCTS INVOLVING SHEET PRODUCTS - A method for forming a tubular sheet product roll includes providing a sheet product roll having a first configuration and a void, centering a rotational axis of the sheet product roll on a longitudinal axis of a first tool, and inserting the first tool into the void of the sheet product roll to define an inner diameter of the void and to form the sheet product roll having a second configuration different from the first configuration. | 08-29-2013 |
20130225385 | METHODS, SYSTEMS AND PRODUCTS INVOLVING SHEET PRODUCTS - A method for forming a tubular sheet product roll includes providing a sheet product roll having a first configuration and a void, centering a rotational axis of the sheet product roll on a longitudinal axis of a first tool, and inserting the first tool into the void of the sheet product roll to define an inner diameter of the void and to form the sheet product roll having a second configuration different from the first configuration. | 08-29-2013 |
20130225386 | METHODS, SYSTEMS AND PRODUCTS INVOLVING SHEET PRODUCTS - A method for forming a tubular sheet product roll includes providing a sheet product roll having a first configuration and a void, centering a rotational axis of the sheet product roll on a longitudinal axis of a first tool, and inserting the first tool into the void of the sheet product roll to define an inner diameter of the void and to form the sheet product roll having a second configuration different from the first configuration. | 08-29-2013 |
Patent application number | Description | Published |
20080256290 | METHOD AND SYSTEM OF RANDOMIZING MEMORY LOCATIONS - A memory system that disperses memory addresses of stings of data throughout a memory is provided. The memory system includes a memory, a central processing unit (CPU) and an address randomizer. The memory is configured to store stings of data. The CPU is configured to direct the storing and retrieving of the strings of data from the memory at select memory addresses. The address randomizer is coupled between the CPU and the memory. Moreover, the address randomizer is configured to disburse the strings of data throughout locations of the memory by changing the select memory addresses directed by the CPU. | 10-16-2008 |
20080256375 | SYSTEM OF INTEGRATED ENVIRONMENATLLY HARDENED ARCHITECTURE FOR SPACE APPLICATION - An environmentally hardened architecture comprises a hybrid processor, a high speed bus having environmentally-sensitive interfaces, an environmentally hardened bus having environmentally-hardened interfaces, and an environmentally-hardened processor communicatively coupled to an environmentally-sensitive interface of the high speed bus and communicatively coupled to an environmentally-hardened interface of the environmentally hardened bus. The hybrid processor includes an environmentally-hardened processing section and an environmentally-sensitive processing section. At least one environmentally-sensitive interface is configured to pass data to and from the environmentally-sensitive processing section and another environmentally-sensitive interface is configured to pass data to and from the environmentally-hardened processing section of the hybrid processor. An environmentally-hardened interface is configured to pass data to and from the environmentally-hardened processing section of the hybrid processor. The environmentally-hardened processor processes critical applications in the environmentally-hardened processing section of the at least one hybrid processor during an environmental event. | 10-16-2008 |
20090257475 | SYSTEM AND METHOD FOR SECURE COMMUNICATION OF COLLECTED AMPHIBIOUS DATA - system and method for secure communication of collected amphibious data is disclosed, which uses direct-sequence, spread spectrum, ultra wideband (DS-SS UWB) communications to enhance the security of the collected amphibious data during transmission over a wireless communication link. The UWB technique used transmits the collected data using very short pulses with low duty cycles. Thus, the power of the transmitted signals can be distributed evenly over a large bandwidth, and buried within the environmental noise (below the noise floor) to produce “stealth” transmissions. The transmitted signals can also be encrypted, which provides a wireless data communication transmission that is immune from jamming and masked from eavesdropping attempts. As one example, a system for secure communication of collected amphibious data is disclosed, which includes a DS-SS UWB transmitter and receiver. The DS-SS UWB transmitter includes a data input unit, a data encryption unit, a UWB encoder unit, a DS spectrum spreader function unit, and a power amplifier unit. The DS-SS UWB receiver includes a receiver front end unit, a data decryption unit, a DS spectrum despreader function unit, and a receiver filter unit. As another example, the DS-SS UWB transmitter and receiver are combined to provide a DS-SS UWB transceiver. | 10-15-2009 |
Patent application number | Description | Published |
20140309004 | Method and system for interpersonal challenging - A web hosting platform is invented to provide advertisement and promotional services of sellers of goods and services to a targeted group of people who congregate to this platform depending on their common interests that translates into common consumption preferences. This platform uses a very pervasive human behavior, interpersonal challenging and is meant to benefit the consumers and sellers of goods and services and create a revenue stream for the web hosting agencies based on an innovative business model. | 10-16-2014 |
20150039362 | ALLOCATION SYSTEM AND METHOD OF DEPLOYING RESOURCES - A system and method for allocating drivers to procure targets, such as automobiles. These targets are then transported to a desired drop-off destination. The entire system is automated, such that a requestor may hire drivers that are certified by the system and would satisfy requirements associated with the target, such as proper driver's license and location of the driver relative to the target. The system is powered by an internet based mobile application that is designed to match individual drivers to auto dealers, auction houses, driving transport companies and other businesses and individuals (“requestors”) seeking to move automobiles, goods, services, tasks, etc. from one location to another. The system has been designed to find, organize, and manage drivers and all aspects of the trip on a real time basis and reduce the cost of the existing system. | 02-05-2015 |
20150039365 | DIGITAL VEHICLE TAG AND METHOD OF INTEGRATION IN VEHICLE ALLOCATION SYSTEM - A system and method for allocating drivers to procure targets, such as automobiles. These targets are then transported to a desired drop-off destination. The entire system is automated, such that a requestor may hire drivers that are certified by the system and would satisfy requirements associated with the target, such as proper driver's license and location of the driver relative to the target. The system is powered by an internet based mobile application that is designed to match individual drivers to auto dealers, auction houses, driving transport companies and other businesses and individuals (“requestors”) seeking to move automobiles, goods, services, tasks, etc. from one location to another. The system has been designed to find, organize, and manage drivers and all aspects of the trip on a real time basis and reduce the cost of the existing system. | 02-05-2015 |
20150039366 | Mobile application for automobile business to manage driver-based transporting of vehicles - A method and system of web hosting platform is provided based on an internet based mobile application that is designed to match individual DRIVER(S) to auto dealers, auction houses, driving transport companies and other businesses and individuals (REQUESTORS) seeking to move automobiles, goods, services, tasks etc. from one location to another. The system has been designed to find, organize, manage DRIVERS and all aspects of the trip on a real time basis and reduce the cost of the existing system. | 02-05-2015 |
Patent application number | Description | Published |
20080289422 | ULTRASONIC SENSOR SYSTEM FOR WEB-GUIDING APPARATUS - A sensor system for determining the position of at least two edges of at least one web material traveling along a predetermined path. In one embodiment, the sensor system has at least one transmitter block having a plurality of transmitters capable of selectively transmitting ultrasonic signals and at least one receiver block having a plurality of receivers capable of generating receiver output signals in response to the receivers receiving at least a portion of the ultrasonic signals transmitted by the at least one transmitter block. The receiver block is spaced a distance from the transmitter block so as to define a continuous sensor field of view therebetween whereby at least a portion of the at least one web material traveling along a predetermined travel path interferes with at least a portion of the ultrasonic signals transmitted by the at least one transmitter block. The receiver output signals generated by the at least one receiver block is indicative of the position of the web of material as the same is moved along the travel path between the transmitter block and the receiver block. In an alternative embodiment, the functions of the at least one transmitter block and the at least one receiver block are performed essentially equivalently by at least one transceiver block and at least one reflector. | 11-27-2008 |
20080296105 | Tension control system for a web of material - A tension control assembly including a rotating member, a braking member, at least one brake pad, a means for driving the at least one brake pad against the braking member, and a temperature sensing means. The braking member is attached to the rotating member. The at least one brake pad is positioned adjacent to the braking member. The means for driving the at least one brake pad against the braking member forces frictional contact between the at least one brake pad and the braking member, thus providing torque to the rotating member. The temperature sensing means measures the temperature of the at least one brake pad. | 12-04-2008 |
20140209655 | SENSOR CONTROLLER FOR INTERPRETING NATURAL INTERACTION SENSOR FOR WEB HANDLING - A sensor controller for web handling applications is described. The sensor controller is provided with a first port, a second port, a computer readable medium, and a processor. The first port receives a sequence of data frames capturing an area of a material web having a width to height ratio between 0.10 and 100. The computer readable medium stores logic indicative of identifying properties of a first group of data points of a feature of the material web extending in a web direction of travel. The processor scans the sequence of data frames to locate a transition between a property of the first group of data points and a property of a second group of data points in the data frames and generates a series of location signals indicative of lateral locations of the transition within the data frames. The second port outputs the location signals. | 07-31-2014 |
20150227482 | BUS AUTO-ADDRESSING SYSTEM - The invention pertains to automatically addressing devices on a network. The controller tests each address from a list of available addresses. If the control device receives a response the corresponding address is eliminated from the list of available addresses. The control device sends an arming signal which is received by all participating devices. The devices prepare for a triggering signal. When the trigger signal is received each device waits a random amount of time. During this time each device looks for communication on the bus, if communication is detected the device quits timing and remains unaddressed, if not it sends a signal to the control device to accept the address. | 08-13-2015 |
Patent application number | Description | Published |
20100022465 | METHOD OF TREATING BLEPHARITIS - The present invention relates to a method for treating non-infectious, inflammatory chronic posterior blepharitis in a subject. The present invention also relates to a method for treating chronic posterior blepharitis in a subject for over two weeks. The method comprises identifying a subject in need thereof, and topically administering to the eye of the subject a pharmaceutical formulation consisting essentially of an effective amount azithromycin. The present invention further relates to a method for treating dry eye secondary to blepharitis in a subject. The method comprises the steps of: identifying a subject suffering from dry eye secondary to posterior blepharitis, and topically administering to the eye of the subject a pharmaceutical formulation comprising an effective amount of azithromycin. The present invention further relates to method for reducing contact lens intolerance of a subject due to blepharitis or dry eye secondary to blepharitis. | 01-28-2010 |
20120252756 | Pharmaceutical Compositions and Methods for Treating, Controlling, Ameliorating, or Reversing Conditions of the Eye - A pharmaceutical composition comprises a polyethylene glycol having a molecular weight in the range from about 1,000 to about 10,000, and a water-soluble cellulose derivative having a molecular weight in the range from about 50,000 to 120,000. The composition can further comprise boric acid and/or phosphate, a non-ionic surfactant, and/or an ophthalmic therapeutic agent. The composition is effective in treating, controlling, ameliorating, or reversing one or more conditions or symptoms of dry eye. | 10-04-2012 |
Patent application number | Description | Published |
20140113844 | FUNCTIONALIZED POLYMERS AND OLIGOMERS AS CORROSION INHIBITORS AND ANTIWEAR ADDITIVES - Provided are lubricant compositions and hydrocarbon fluids including one or more lubricant base stocks and an effective amount of one more zero SAP antiwear additives and/or corrosion inhibitor additives, wherein the one more antiwear and/or corrosion inhibitor additives include one or more functionalized polyolefins having one or more pyridazine moieties. Such compositions exhibit improved anti-wear, friction reduction and anti-corrosion properties. | 04-24-2014 |
20140178637 | LOW FRICTION COATINGS WITH IMPROVED ABRASION AND WEAR PROPERTIES AND METHODS OF MAKING - Provided are low friction coatings with improved abrasion, wear resistance and methods of making such coatings. In one form, the coating includes: i) an under layer selected from the group consisting of CrN, TiN, TiAlN, TiAlVN, TiAlVCN, TiSiN, TiSiCN, TiAlSiN and combinations thereof, wherein the under layer ranges in thickness from 0.1 to 100 μm, ii) an adhesion promoting layer selected from the group consisting of Cr, Ti, Si, W, CrC, TiC, SiC, WC, and combinations thereof, wherein the adhesion promoting layer ranges in thickness from 0.1 to 50 μm and is contiguous with a surface of the under layer, and iii) a functional layer selected from the group consisting of a fullerene based composite, a diamond based material, diamond-like-carbon and combinations thereof, wherein the functional layer ranges from 0.1 to 50 μm and is contiguous with a surface of the adhesion promoting layer. | 06-26-2014 |
Patent application number | Description | Published |
20110203791 | COATED SLEEVED OIL AND GAS WELL PRODUCTION DEVICES - Provided are coated sleeved oil and gas well production devices and methods of making and using such coated sleeved devices. In one form, the coated sleeved oil and gas well production device includes one or more cylindrical bodies, one or more sleeves proximal to the outer diameter or inner diameter of the one or more cylindrical bodies, hardbanding on at least a portion of the exposed outer surface, exposed inner surface, or a combination of both exposed outer or inner surface of the one or more sleeves, and a coating on at least a portion of the inner sleeve surface, the outer sleeve surface, or a combination thereof of the one or more sleeves. The coating includes one or more ultra-low friction layers, and one or more buttering layers interposed between the hardbanding and the ultra-low friction coating. The coated sleeved oil and gas well production devices may provide for reduced friction, wear, erosion, corrosion, and deposits for well construction, completion and production of oil and gas. | 08-25-2011 |
20110220348 | Coated Oil and Gas Well Production Devices - Provided are coated oil and gas well production devices and methods of making and using such coated devices. In one form, the coated device includes one or more cylindrical bodies, hardbanding on at least a portion of the exposed outer surface, exposed inner surface, or a combination of both exposed outer or inner surface of the one or more cylindrical bodies, and a coating on at least a portion of the inner surface, the outer surface, or a combination thereof of the one or more cylindrical bodies. The coating includes one or more ultra-low friction layers, and one or more buttering layers interposed between the hardbanding and the ultra-low friction coating. The coated oil and gas well production devices may provide for reduced friction, wear, erosion, corrosion, and deposits for well construction, completion and production of oil and gas. | 09-15-2011 |
20110220415 | ULTRA-LOW FRICTION COATINGS FOR DRILL STEM ASSEMBLIES - Provided are drill stem assemblies with ultra-low friction coatings for subterraneous drilling operations. In one form, the coated drill stem assemblies for subterraneous rotary drilling operations include a body assembly with an exposed outer surface including a drill string coupled to a bottom hole assembly, a coiled tubing coupled to a bottom hole assembly, or a casing string coupled to a bottom hole assembly and an ultra-low friction coating on at least a portion of the exposed outer surface of the body assembly, hardbanding on at least a portion of the exposed outer surface of the body assembly, an ultra-low friction coating on at least a portion of the hardbanding, wherein the ultra-low friction coating comprises one or more ultra-low friction layers, and one or more buttering layers interposed between the hardbanding and the ultra-low friction coating. The coated drill stem assemblies disclosed herein provide for reduced friction, vibration (stick-slip and torsional), abrasion, and wear during straight hole or directional drilling to allow for improved rates of penetration and enable ultra-extended reach drilling with existing top drives. | 09-15-2011 |
20140011719 | ENHANCED DURABILITY PERFORMANCE OF LUBRICANTS USING FUNCTIONALIZED METAL PHOSPHATE NANOPLATELETS - A method for improving wear protection in an engine lubricated with a lubricating oil by using as the lubricating oil a formulated oil having a HTHS viscosity of less than 2.6 cP at 150° C. The formulated oil has a composition including a major amount of a lubricating oil base stock and a minor amount of metal phosphate nanoplatelets. The metal phosphate nanoplatelets are dispersed in the lubricating oil base stock sufficient for the formulated oil to pass wear protection requirements of one or more engine tests selected from TU3M, Sequence IIIG, Sequence IVA and OM646LA. Also provided are lubricating engine oil composition having improved wear protection. | 01-09-2014 |
20140038862 | ANTI-WEAR PERFORMANCE OF LUBRICANTS USING CARBON NANOPLATELETS - Provided are a lubricating engine oil and a method of improving wear protection in an engine lubricated with such lubricating oil. The method includes using as the lubricating oil a formulated oil comprising a lubricating oil base stock as a major component, an antiwear additive as a first minor component, and carbon nanoplatelets as a second minor component. The carbon nanoplatelets are dispersed in said lubricating oil base stock. Wear protection is improved as compared to wear protection achieved using a lubricating oil not containing carbon nanoplatelets as a second minor component. A synergy exists between carbon nanoplatelets and other major components of lubricants, especially with zinc dialkyldithiophosphate (ZDDP) or other phosphate antiwear additives, that helps to form a nano-composite wear resistant and low friction tribofilm both on ferrous and non-ferrous surfaces (e.g., carbon coatings, ceramic coatings, polymeric coatings, and the like) of engines/machines. | 02-06-2014 |
Patent application number | Description | Published |
20080214125 | Method and Apparatus For Dynamically Adjusting a Transmitter's Impedance and Implementing a Hybrid Power Amplifier Therein Which Selectively Connects Linear and Switch-Mode Power Amplifiers in Series - A method and apparatus for dynamically adjusting the impedance between a transmitter's power amplifier (PA) and antenna to efficiently transfer power from the PA to the antenna. The impedance between the PA and the antenna is adjusted based on power level measurements and/or PA direct current (DC) consumption measurements, depending on whether the PA is a linear PA or a switch-mode PA. In another embodiment, a hybrid PA including a first stage linear PA and a second stage switch-mode PA is implemented in a transmitter. The hybrid PA selectively connects the output of the first stage linear PA to one of the input of the second stage switch-mode PA and the output of the hybrid PA, depending on the output power level of the first stage linear PA, the output power level of the hybrid PA, or a requirement indicated by a transmit power control (TPC) command. | 09-04-2008 |
20100226330 | METHOD FOR A RADIO FREQUENCY (RF) SAMPLING APPARATUS WITH ARRAYS OF TIME INTERLEAVED SAMPLERS AND SCENARIO BASED DYNAMIC RESOURCE ALLOCATION - A method and apparatus for dynamic resource allocation of an RF sampling system based on a signal quality measurement determined by generating a plurality of time-interleaved samples from a received radio frequency (RF) signal and combining the plurality of time-interleaved samples to generate the signal quality. | 09-09-2010 |
20120063373 | METHOD AND APPARATUS FOR DYNAMIC BANDWIDTH PROVISIONING IN FREQUENCY DIVISION DUPLEX SYSTEMS - A method and apparatus are described that provides flexible spectrum usage by using a paired frequency division duplex (FDD) spectrum to enable dynamic access in television white space (TVWS), sub-leased spectrum or unlicensed spectrum, (e.g., industrial, scientific and medical (ISM) bands), in a femto cell environment or the like. Elastic FDD (E-FDD) enables femto cell operation in TVWS, sub-leased spectrum and/or unlicensed spectrum, either simultaneously with licensed spectrum or as an alternate channel to licensed spectrum. E-FDD enables dynamic asymmetric bandwidth allocation for uplink (UL) and downlink (DL) in FDD, and enables variable duplex spacing, (i.e., using FDD with minimum duplex spacing between DL and UL spectrum, or, using hybrid-FDD, (FDD in a time duplexed fashion), when a spectrum gap between the UL and DL spectrum is below a certain minimum threshold. Additionally, the signaling enhancements to implement E-FDD are also provided. | 03-15-2012 |
20140010103 | RADIO FREQUENCY (RF) SAMPLING APPARATUS WITH ARRAYS OF TIME INTERLEAVED SAMPLERS AND SCENARIO BASED DYNAMIC RESOURCE ALLOCATION - A wireless transmit/receive unit (WTRU) is described. The WTRU includes a front-end unit (FEU), a signal processing unit (SPU), and a resource management unit (RMU). The FEU receives a radio frequency (RF) signal, generates time-interleaved samples, an includes: a first array of first time-interleaved samplers, a second array of second time-interleaved samplers, and a third array of third time-interleaved samplers. The SPU receives and combines the plurality of time-interleaved samples and generates a signal quality measurement and in-phase and quadrature-phase (IQ) complex samples. The RMU receives the signal quality measurement and allocates FEU resources in conjunction with a front-end unit controller (FEUC) based on the signal quality measurement. The FEUC generates control signals based on the received signal quality measurement from the RMU. | 01-09-2014 |