Patent application number | Description | Published |
20120200266 | Method and Circuitry to Calculate the State of Charge of a Battery/Cell - The present inventions, in one aspect, are directed to techniques and/or circuitry to applying a current pulse to the terminals of the battery during a charge, measuring a voltage at the terminals of the battery, determining a relationship of an open circuit voltage to an amount of charge in the battery using data which is representative of a state of health of the battery, calculating an open circuit voltage of the battery using the voltage measured at the terminals of the battery, a current applied to or removed from the battery and an impedance of the battery, and determining a state of charge of the battery using (i) the calculated open circuit voltage and (ii) the relationship of the open circuit voltage to the amount of charge. | 08-09-2012 |
20140021959 | Method and Circuitry to Adaptively Charge a Battery/Cell Using the State of Health Thereof - The present inventions, in one aspect, are directed to techniques and/or circuitry to determining data which is representative of the state of health, or a change therein, of the battery using the data which is representative of (i) the relaxation time of the battery and/or (ii) the overpotential of the battery. In another aspect the present inventions are directed to techniques and/or circuitry to adapt one or more characteristics of a charge signal using data which is representative of the state of health, or a change therein, of the battery. In yet another aspect the present inventions are directed to techniques and/or circuitry to determine a state of charge of the battery using data which is representative of the state of health, or a change therein, of the battery. | 01-23-2014 |
20140084846 | Method and Circuitry to Adaptively Charge a Battery/Cell - The present inventions, in one aspect, are directed to techniques and/or circuitry to applying a charge pulse to the terminals of the battery during a charging operation, measure a plurality of voltages of the battery which are in response to the first charge pulse, determine a charge pulse voltage (CPV) of the battery, wherein the charge pulse voltage is a peak voltage which is in response to the first charge pulse, determine whether the CPV of the battery is within a predetermined range or greater than a predetermined upper limit value and adapt one or more characteristics of a charge packet if the CPV is outside the predetermined range or is greater than a predetermined upper limit value. | 03-27-2014 |
20150153417 | Method and Circuitry to Calculate the State of Charge of a Battery/Cell - The present inventions, in one aspect, are directed to techniques and/or circuitry to applying a current pulse to the terminals of the battery during a charge, measuring a voltage at the terminals of the battery, selecting a relationship of an open circuit voltage to an amount of charge in the battery using data which is representative of a state of health of the battery, calculating an open circuit voltage of the battery using the voltage measured at the terminals of the battery, a current applied to or removed from the battery and an impedance of the battery, and determining a state of charge of the battery using (i) the calculated open circuit voltage and (ii) the relationship of the open circuit voltage to the amount of charge. | 06-04-2015 |
Patent application number | Description | Published |
20090054246 | Virus-like platform for rapid vaccine discovery - The invention is directed to virus-like particles (VLPs) of an RNA bacteriophage that (a) comprises a coat polypeptide of said phage modified by insertion of a heterologous peptide that is displayed on said VLP and (b) encapsidates said bacteriophage mRNA as well as populations of these VLPs, and their uses. The invention is further directed to VLPs that encapsidate heterologous substances, as well as populations of these VLPs and their uses. | 02-26-2009 |
20110104203 | VIRUS-LIKE PLATFORM FOR RAPID VACCINE DISCOVERY - The invention is directed to virus-like particles (VLPs) of an RNA bacteriophage that (a) comprises a coat polypeptide of said phage modified by insertion of a heterologous peptide that is displayed on said VLP and (b) encapsidates said bacteriophage mRNA as well as populations of these VLPs, and their uses. The invention is further directed to VLPs that encapsidate heterologous substances, as well as populations of these VLPs and their uses. | 05-05-2011 |
20120295813 | PLASMIDS AND METHODS FOR PEPTIDE DISPLAY AND AFFINITY-SELECTION ON VIRUS-LIKE PARTICLES OF RNA BACTERIOPHAGES - The present invention relates to a system and method for controlling peptide display valency on virus-like particles (VLPs), especially including MS2 VLPs. In this method, large amounts of wild-type and low quantities of single-chain dimer coat proteins may be produced from a single RNA. Valency is controlled in immunogen (vaccine) production by providing a system that allows the production of large amounts of wild-type and low quantities of single-chain dimer coating proteins from a single RNA, allowing facile adjustment of display valency levels on VLPs, especially MS2 VLPS over a wide range, from few than one-on average—to as many as ninety per particle. This facilitates the production of immunogens and vaccines, including VLPs exhibiting low valency. Nucleic acid constructs useful in the expression of virus-like particles are disclosed, comprised of a coat polypeptide of MS2 modified by insertion of a heterologous peptide, wherein the heterologous peptide is displayed on the virus-like particle and encapsidates MS2 niRNA. Nucleic acid constructs are also disclosed which are useful in the expression of virus-like particles comprised of a coat polypeptide of PP7 modified by insertion of a heterologous peptide, wherein the heterologous peptide is displayed on the virus-like particle and encapsidates PP7 mRNA. | 11-22-2012 |
20120308592 | Immunogenic HPV L2-Containing VLPs and Related Compositions, Constructs, and Therapeutic Methods - The invention provides immunotherapeutic and prophylactic bacteriophage viral-like particle (VLPs) which are useful in the treatment and prevention of human papillomavirus (HPV) infections and related disorders, including cervical cancer and persistent infections associated with HPV. Related compositions (e.g. vaccines), nucleic acid constructs, and therapeutic methods are also provided. VLPs and related compositions of the invention induce high titer antibody responses against HPV L2 and protect against HPV challenge in vivo. VLPs, VLP-containing compositions, and therapeutic methods of the invention induce an immunogenic response against HPV infection, confer immunity against HPV infection, protect against HPV infection, and reduce the likelihood of infection by HPV infection. | 12-06-2012 |
20130017210 | DISPLAY OF ANTIBODY FRAGMENTS ON VIRUS-LIKE PARTICLES OF RNA BACTERIOPHAGES - The invention enables the display of antibody single-chain variable fragments (scFv's on virus-like particles (VLPs) of bacteriophages such as MS2. The VLPs encapsidate mRNA encoding the coat protein from which it assembles, enabling the recovery by reverse transcription and PGR of affinity-selected sequences from scFv libraries. Related virus-like particles, method for constructing a library of scFv-VLPs, drug delivery vehicles comprising one or more pharmaceutically-active ingredients, biomedical imaging agents, assays, and kits are also provided. | 01-17-2013 |
20130149336 | Methods for Screening Viral Like Particles and Identifying Neutralizing Epitopes and Related Vaccines, Constructs, and Libraries - The invention is directed to methods of screening immunogenic viral like particles and related immunogenic compositions and diagnostic techniques. In one embodiment, the invention provides methods of screening immunogenic viral like particles containing peptides corresponding to epitope regions of a wide variety of pathogens, including viruses, bacteria, parasites, and microbes. Non-infectious antigens and allergens of interest can also be screened as described herein. Immunization, therapeutic and diagnostic applications are also described for the compositions and methods according to the invention. | 06-13-2013 |
20130302371 | Immunogenic Respiratory Syncytial Virus Glycoprotein-Containing VLPs and Related Compositions, Constructs, and Therapeutic Methods - The invention provides immunotherapeutic and prophylactic bacteriophage viral-like particle (VLPs) which are useful in the treatment and prevention of Respiratory Syncytial Virus (RSV) infections and related disorders, including bronchiolitis and viral pneumonia. Related compositions (e.g. vaccines), nucleic acid constructs, and therapeutic methods are also provided. VLPs and related compositions of the invention induce high titer antibody responses against RSV. VLPs, VLP-containing compositions, and therapeutic methods of the invention induce an immunogenic response against RSV infection, confer immunity against RSV infection, protect against RSV infection, and reduce the likelihood of infection by RSV infection. | 11-14-2013 |
20140105924 | Immunogenic HPV L2-Containing VLPs and Related Compositions, Constructs, and Therapeutic Methods - The invention provides immunotherapeutic and prophylactic bacteriophage viral-like particle (VLPs) which are useful in the treatment and prevention of human papillomavirus (HPV) infections and related disorders, including cervical cancer and persistent infections associated with HPV. Related compositions (e.g. vaccines), nucleic acid constructs, and therapeutic methods are also provided. VLPs and related compositions of the invention induce high titer antibody responses against HPV L2 and protect against HPV challenge in vivo. VLPs, VLP-containing compositions, and therapeutic methods of the invention induce an immunogenic response against HPV infection, confer immunity against HPV infection, protect against HPV infection, and reduce the likelihood of infection by HPV infection. | 04-17-2014 |
20140106982 | PLASMIDS AND METHODS FOR PEPTIDE DISPLAY AND AFFINITY-SELECTION ON VIRUS-LIKE PARTICLES OF RNA BACTERIOPHAGES - The present invention relates to a system and method for controlling peptide display valency on virus-like particles (VLPs), especially including MS2 or PP7 VLPs. In this method, large amounts of wild-type and low quantities of single-chain dimer coat proteins may be produced from a single RNA. Valency is controlled in immunogen (vaccine) production by providing a system that allows the production of large amounts of wild-type and low quantities of single-chain dimer coating proteins from a single RNA, allowing facile adjustment of display valency levels on bacteriophage VLPs, especially MS2 or PP7 VLPs over a wide range, from few than one—on average—to as many as ninety per particle. This facilitates the production of immunogens and vaccines, including VLPs exhibiting low valency. Nucleic acid constructs useful in the expression of virus-like particles are disclosed, comprised of a coat polypeptide of bacteriophage such as MS2 or PP7 modified by insertion of a heterologous peptide, optionally comprising a carbohydrate mimotope, wherein the heterologous peptide is displayed on the virus-like particle and encapsidates bacteriphage mRNA. | 04-17-2014 |
Patent application number | Description | Published |
20120146341 | Integration of Vertical Adjustability in an Electric Strike - An electric strike which provides vertical adjustability of the position of the strike relative to the latch bolt in the closure with modification to the doorframe on the dust box. A ramp element in the strike housing is adjustable relative to the strike and is securable at the time of installation to align the center of the latch bolt and strike. The ramp element has a channel to allow entry and exit of a latch bolt having a dead latch. A keeper engages the dead latch and maintains it in a retracted position when the closure is locked and is released when the electric latch solenoid is energized. | 06-14-2012 |
20130067966 | Electronic Cable Lock System - An electromechanical cable lock system comprising an electromechanical locking mechanism including a cable having at least one plug end receivable in the locking mechanism and a plurality of slidable locking plates engageable with the plug in said locking mechanism. At least one of the locking plates is capable of movement in a first direction different from the movement of a second of said locking plates in a second direction. The locking plates are driven by a motor-driven cam mechanism. The system includes a card reader or other credential verifying device and an electronic controller for activating the locking mechanism, The system also includes a barrel lock for over-riding the electronic controller. A plurality of features can detect and alarm in the event of tampering or unauthorized entry. | 03-21-2013 |
20130067969 | Electronic Cabinet/Drawer Lock System - An electronic wireless locking system comprising an external assembly and an internal assembly disposable on respective sides of a door or drawer. The external assembly includes a cover housing, a knob having a shaft, a card/credential reader, a status indicator, a wireless communication capability, a wire harness and a jump port plug. The internal assembly comprises a rotation link matable with the external shaft, a latch bolt, a circuit board and controller, and a locking mechanism including a rack and pinion gear set linking the rotation link with the latch bolt. A blocker inhibits the latch bolt from unlocking until authorized to rotate 90°, permitting the latch bolt to be withdrawn from a strike plate by manual rotation of the knob. An optional mechanical key override feature may also be provided. The system may further include a preload sensor and a device locked sensor. | 03-21-2013 |
Patent application number | Description | Published |
20120205239 | ANODE ASSEMBLY, SYSTEM INCLUDING THE ASSEMBLY, AND METHOD OF USING SAME - The present invention relates to an anode assembly for use in an electrolytic cell for recovery of metal. The assembly includes a hanger bar, a first perimeter bar, a second perimeter bar, optionally one or more center conductor bars, a base bar, a first tab coupled to the first perimeter bar and/or the base bar, and a second tab coupled to the second perimeter bar and/or the base bar. The assembly may also include insulating separators coupled to the tabs and/or insulators coupled to an active area of the anode assembly. A system includes the anode assembly, a cathode assembly, and a tank. | 08-16-2012 |
20120205254 | CONTACT BAR ASSEMBLY, SYSTEM INCLUDING THE CONTACT BAR ASSEMBLY, AND METHOD OF USING SAME - The present invention relates to a contact bar assembly for use in a multi-cell electrolytic system for recovery of metal, to a system including the contact bar assembly, and to a method of using the assembly and system. The contact bar assembly includes a base cap board, a primary bar having a plurality of primary bar structures formed thereon, an auxiliary bar having a plurality of auxiliary bar structures formed thereon, and a top cap board, wherein the base cap board includes slots to receive the primary bar and the auxiliary bar, and wherein the top cap board includes a plurality of openings to receive the plurality of primary bar structures and the plurality of auxiliary bar structures. A system includes the contact bar assembly, an anode assembly, a cathode assembly, and a tank. | 08-16-2012 |
20130153437 | CATHODE ASSEMBLY INCLUDING A BARRIER, SYSTEM INCLUDING THE ASSEMBLY AND METHOD FOR USING SAME - A cathode assembly, a system including the cathode assembly, and method of using the assembly and system are disclosed. The cathode assembly includes a conductive element and a barrier element proximate the conductive element. The assembly, system and method provide for improved metal powder formation. The system may be stationary or portable. | 06-20-2013 |
Patent application number | Description | Published |
20090090163 | WHEEL MEASUREMENT SYSTEMS AND METHODS - An improved maintenance, inspection, and/or measurement solution is provided. An embodiment of the invention includes a handheld measurement device for measuring an object, such as a railway wheel on a train. The handheld measurement device can comprise a single unit to provide one handed operation and can include various features, such as onboard evaluation, a graphical user interface, and/or a self-health monitor. Additionally, aspects of the invention provide an inspection environment that incorporates preliminary measurement data, wireless communications, and/or historical data into the measurement and evaluation process. | 04-09-2009 |
20090207420 | PORTABLE ELECTRONIC MEASUREMENT - The invention provides a handheld electronic gauge that is configured to obtain measurement data for an object, such as a wheel, rail, axle, or the like. The gauge includes one or more position sensors that automatically determine when the gauge is in a measurement position. The invention also provides a handheld computing device that can automatically determine when a gauge is in the measurement position and automatically obtain measurement data using the gauge. As a result, the invention provides a solution for measuring an object, such as a railway wheel, that is portable and capable of repeatedly providing various desired measurements, irrespective of the operator. | 08-20-2009 |
20100031756 | Rotational component torque measurement and monitoring system - A system and method for measuring torque on a rotating component, comprising of signal-producing components which are applied to the rotating component, and a means for obtaining the signals produced by said signal producing components, in which at least two signal producing components are applied to the rotating component with some linear separation between the two signal producing components and their corresponding devices for obtaining signals produced, such that torque applied to the rotating component will cause a change in phase between the signals received from each of the signal-producing components and thus permit the measurement of torque based on this change in phase; one embodiment of this invention comprising two magnetic rings, one at either end of a driveshaft, with sensor coils placed near to each magnetic ring such that an alternating electrical current is produced, the comparative phase between these currents permitting measurement of torque on the driveshaft. | 02-11-2010 |