Kiel, US
Dan Kiel, Spring Hill, KS US
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20110014225 | CROSS-REACTIVE DETERMINANTS AND METHODS FOR THEIR IDENTIFICATION - Compositions and methods for determining immunologically cross-reactive molecules comprising a cross-reactive antigenic determinant are provided, in particular for determining proteins comprising cross-reactive antigenic determinants, in particular for determining proteins that are cross-reactive based on serological screens using sequential immunological challenges to an animal, including determining cross-reactive | 01-20-2011 |
Garrett George Kiel, San Francisco, CA US
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20160103585 | FACILITATING DYNAMIC CUSTOMIZATION OF REPORTING TOOLS IN AN ON-DEMAND SERVICES ENVIRONMENT - In accordance with embodiments, there are provided mechanisms and methods for facilitating dynamic customization of reporting tools in an on-demand services environment in a multi-tenant environment according to one embodiment. In one embodiment and by way of example, a method includes importing, by a database system, a first application from a computing system associated with a third-party entity, where the first application is associated with the third-party entity and first one or more reporting forms of a plurality of reporting forms. The method may further include integrating, by the database system, the first application with a second application to generate an integrated application, where the second application includes a local application and is independent of the first application. The second application may be associated with second one or more reporting forms of the plurality of reporting forms. The method may further include associating, by the database system, a set of integrated properties of the integrated application with a reporting tool, and displaying, by a display device, the reporting tool to be used to facilitate building of one or more reports based on the set of integrated properties, where the one or more reports include at least one of the first and second one or more reporting forms. | 04-14-2016 |
Jeffrey Kiel, Raleigh, NC US
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20100211933 | DEBUGGING AND PERFOMANCE ANALYSIS OF APPLICATIONS - While an application is still running and using a resource that the application has already allocated, real-time capture is used to allow for a minimal overhead, quick turnaround solution for debugging and performance analysis. Application programming interface interception can be used to construct a database of resource usage that can then be mined for dependencies. | 08-19-2010 |
Jeffrey S. Kiel, Gainesville, GA US
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20080242728 | PHENOLIC ACID SALTS OF GABAPENTIN IN SOLID DOSAGE FORMS AND METHODS OF USE - The present invention relates to pharmaceutical compositions of gabapentin tannate in solid dosage form, processes for production of those compositions and methods of use of those compositions. Tannate salts of active pharmaceutical ingredients are used in sustained release applications and to improve certain organoleptic properties such as taste. The process may utilize either natural or synthetic tannic acid. | 10-02-2008 |
20090062191 | Composition for maintaining gastrointestinal homeostasis - The invention relates to a suspension of albumin and tannic acid for maintaining gastrointestinal homeostasis. | 03-05-2009 |
20090149815 | Medication dosing system based upon patient classification codes - Medication dosing system for one or more medications based on patient classification codes and standardized dosage units, where the patient classification codes are correlated with one or more characteristics of the patient, such as weight or age, and each medication is formulated so that the dosage unit for the classification code contains the recommended amount of medication for patients within that classification code. | 06-11-2009 |
20100069305 | Composition for maintaining gastrointestinal homeostasis - The invention relates to a suspension of albumin and tannic acid for maintaining gastrointestinal homeostasis. | 03-18-2010 |
20100120776 | Carbocysteine medical foods - Medical foods containing carbocysteine and designed for buccal absorption; useful for treating conditions that benefit from administration of an antioxidant, immunostimulant, and/or mucoregulator, such as COPD. | 05-13-2010 |
20110288079 | Tannate Compositions, Methods of Making and Methods of Use - Tannate compositions containing active pharmaceutical ingredients to be used for treating nausea, vomiting, pain, convulsions, and insomnia and manufacturing processes for preparing the tannate compositions. | 11-24-2011 |
20150272882 | Sotalol Compositions and Uses of the Same - The present invention provides oral solutions containing sotalol hydrochloride which advantageously avoid swallowing while providing with improved stability. The present invention also relates to methods of using the oral solutions for treatment of diseases and disorders, such as delay in reoccurrence of atrial fibrillation/atrial flutter and/or ventricular arrhythmias. | 10-01-2015 |
Jeffrey T. Kiel, Raleigh, NC US
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20090037774 | CLIENT SERVER SYSTEM FOR ANALYSIS AND PERFORMANCE TUNING OF REMOTE GRAPHICS DEVICES - Embodiments of the invention provide a data communications protocol and client server architecture used for the performance analysis and debugging of a graphics application running on a remote device. The remote device may be a hand-held video game console, a mobile phone, or convergence device, but may also be a personal computer system. A graphical application debugger may include a host component and a target component. The host component executes on a host system and presents a debugging interface to a developer. The target component may record data related to the performance of a graphics pipeline on the target device and transmit this data back to the host system over a communication link. The target component may be included as part of an instrumented version of a graphics device driver. | 02-05-2009 |
20100169654 | METHOD FOR AUTHOR VERIFICATION AND SOFTWARE AUTHORIZATION - Embodiments of the present invention are directed to a computer-implemented method for author verification and authorization of object code. In one embodiment, program object code is linked with a plurality of data blocks to create linked object code and a MAP file. Thereafter, author verification is performed by executing a plurality of comparisons between the linked object code and the MAP file. In another embodiment, a digital signing procedure is performed on linked object code by creating a signature data block. The signature data block is then encrypted and written to the linked object code to create digitally-signed object code. In another embodiment, an application program embodied in linked object code generates a data packet. The data packet is then compared to a previously-generated signature data packet from the linked object code to determine if the linked object code is authorized. | 07-01-2010 |
20140146062 | SYSTEM, METHOD, AND COMPUTER PROGRAM PRODUCT FOR DEBUGGING GRAPHICS PROGRAMS LOCALLY UTILIZING A SYSTEM WITH A SINGLE GPU - A system, method, and computer program product are provided for debugging graphics programs via a system with a single graphics processing unit. The method includes the steps of storing an initial state of an application programming interface context in a memory, intercepting a stream of API commands associated with the frame, transmitting the stream of API commands to a software layer that implements the API to render the frame, and in response to a breakpoint, storing a graphics processing unit context in the memory. The initial state of the API context corresponds to the start of a frame, and the stream of API commands are generated by a graphics application. | 05-29-2014 |
Johnathan L. Kiel, Brooks City-Base, TX US
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20090004644 | METHODS AND COMPOSITIONS FOR PROCESSES OF RAPID SELECTION AND PRODUCTION OF NUCLEIC ACID APTAMERS - Embodiments herein relate to compositions and methods for making and using aptamers, for example, DNA aptamers (DCEs) and/or RNA aptamers. In some embodiments, methods relate to making and amplifying target DCEs. In certain embodiments, methods for making capture elements or aptamers concern using a reporter moiety and signal reducing moiety prior to amplifying a target-specific capture element. In some embodiments, methods disclosed herein may be used to rapidly generate large quantities of aptamers such as DCEs directed to a particular target agent. Some embodiments relate to systems for performing automated generation of aptamers. | 01-01-2009 |
20110027851 | COMPOSITIONS, METHODS AND USES FOR BIOSYNTHETIC PLASMID INTEGRATED CAPTURE ELEMENTS - Embodiments herein report compositions, systems and methods for making and using plasmid vectors and nanotube complexes. In certain embodiments, compositions, systems and methods herein include making plasmid vectors having aptamer inserts. In some embodiments, methods disclosed herein may be used to rapidly generate large quantities of plasmid vectors having aptamer inserts directed to a particular target agent. Other aspects concern plasmid constructs associated with organic semiconductors. Yet other aspects concern complexes of nanotubes associated with dsDNA aptamers and tracking molecules. | 02-03-2011 |
Johnathan L. Kiel, Universal City, TX US
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20120021004 | MEDIUM AND METHOD OF DERIVING AND USING A MUTATED BACTERIA STRAIN - A new strain of | 01-26-2012 |
20120134877 | METHODS FOR NEUTRALIZING ANTHRAX OR ANTHRAX SPORES - The present invention concerns methods, compositions and apparatus for neutralizing bioagents, wherein bioagents comprise biowarfare agents, biohazardous agents, biological agents and/or infectious agents. The methods comprise exposing the bioagent to an organic semiconductor and exposing the bioagent and organic semiconductor to a source of energy. Although any source of energy is contemplated, in some embodiments the energy comprises visible light, ultraviolet, infrared, radiofrequency, microwave, laser radiation, pulsed corona discharge or electron beam radiation. Exemplary organic semiconductors include DAT and DALM. In certain embodiments, the organic semiconductor may be attached to one or more binding moieties, such as an antibody, antibody fragment, or nucleic acid ligand. Preferably, the binding moiety has a binding affinity for one or more bioagents to be neutralized. Other embodiments concern an apparatus comprising an organic semiconductor and an energy source. In preferred embodiments, the methods, compositions and apparatus are used for neutralizing anthrax spores. | 05-31-2012 |
20120157670 | Aptamer-based assays - We describe examples using aptamers for capturing and reporting the presence of a target, such as a pathogen. Examples described here include a set of aptamers that are specific to | 06-21-2012 |
20130040305 | COMPOSITIONS, METHODS AND USES FOR BIOSYNTHETIC PLASMID INTEGRATED CAPTURE ELEMENTS - Embodiments herein report compositions, systems and methods for making and using plasmid vectors and nanotube complexes. In certain embodiments, compositions, systems and methods herein include making plasmid vectors having aptamer inserts. In some embodiments, methods disclosed herein may be used to rapidly generate large quantities of plasmid vectors having aptamer inserts directed to a particular target agent. Other aspects concern plasmid constructs associated with organic semiconductors. Yet other aspects concern complexes of nanotubes associated with dsDNA aptamers and tracking molecules. | 02-14-2013 |
Johnathan Lloyd Kiel, Universal City, TX US
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20100285052 | Chemically Programmable Immunity - Methods and compositions for immediately immunizing an individual against any molecule or compound are provided. The present invention is directed to an immunity linker with at least two sites; (1) at least one first binding site that binds to an immune response component in an individual, and (2) at least one second binding site that binds specifically to a desired compound or molecule, the target. The second binding sites are preferably thiolated aptamers that have the benefit of increased stability, resistance to degradation and longer circulating half life. Methods of making and using pharmaceutical compositions including immunity linker molecules having a thiolated aptamer are also provided. | 11-11-2010 |
Jonathan L. Kiel, Universal City, TX US
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20090053725 | Using DNA aptamers and quantum dots for the detection of proteins or other targets - The solutions provided here use DNA aptamers and quantum dots for the detection of bacteria, viruses, proteins or other targets. An example of a method described here comprises: providing a complex of DNA complementary strands, one strand being an aptamer, having one strand covalently linked to a quantum dot, and having the other strand linked to a quencher; and contacting said complex of DNA complementary strands with a microorganism or components thereof, under conditions that permit binding of said aptamer with said microorganism or components thereof. In some examples described here, the methods and systems are extremely simple to use and appear to have several advantages over the traditional ELISA. Since no blocking steps are required and the number of washing steps is reduced, the time required to conduct the test is greatly reduced. In some examples described here, a quantum dot aptamer complex comprises one strand of a duplex DNA molecule linked to the quantum dot by an amide bond. It does not matter if the aptamer or the complimentary strand is attached. However, the strand that is not attached contains a non-radiative quencher. Upon addition of the aptamers' target, the amount of light emitted by the quantum dots increases. In some examples described here, the methods and systems can also be used in reverse, with the aptamers' target immobilized on a microtiter plate. This permits an assay like a competitive immuno-assay. | 02-26-2009 |
Jonathan William Kiel, Ardmore, PA US
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20140295406 | Portable Device for Detection of Harmful Substances - A self-contained apparatus and methods for detecting the presence of any specified substance in any medium. A sample of the medium is placed in a capsule, along with a solvent and a sensor configured to test for a target analyte. The solvent comes into contact with the medium in the capsule, and the capsule is agitated to create a dispersion in the solvent of a portion of any target analyte present in the medium. A release mechanism configured to cause conduction of the dispersion to the sensor, so that the sensor produces an indication of presence of the target analyte if the target analyte is present in the medium. The apparatus uses a disposable capsule where the medium in question is placed and the disposable capsule is placed inside a reader and analyzed for presence of the harmful substance. | 10-02-2014 |
Kenneth Ray Kiel, Columbus, IN US
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20140083074 | Crop Divider Hinge Kit and Method - Provided is a simple, inexpensive, truly feasible technical solution that readily permits do-it-yourself retrofitting of existing combine harvester heads to allow their crop dividers to pivot out of the way for transport. Provided is a retrofit hinge kit adapted for use with square tube frames and methods for its use. | 03-27-2014 |
20150047309 | Crop Divider Hinge Kit and Method - Provided is a crop divider hinge kit and method of installation and use that facilitates do-it-yourself retrofitting of existing combine harvester heads to allow their crop dividers to pivot out of the way for transport. Hinge kits may be adapted for use with frames having a square tube portion and may comprise a replacement portion of square tubing pivotably connected with a sleeve portion adapted to receive therein and be affixed to a cut portion of the square tube frame. Quick-disconnect fastening mechanisms may be used in connection with hinge kits, including in connection with removably fastening crop divider support members. | 02-19-2015 |
Mark D. Kiel, Bensenville, IL US
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20080217198 | Drinking cup identification method and system comprising individal identifying indicia associated with each cup in a group of identical cups so as to facilitate visual discrimation of one cup form another - According to the invention, an identification system for disposable drinking cups is provided, which system comprises an identification system for a plurality of disposable drinking cups, said drinking cups being made from plastic, plastic composites, bio-based materials, fiber-based materials or other configurable materials, each of the drinking cups being provided with a unique identifying indicia by way of selection from a plurality of indicia, said indicia being a plurality of distinct areas associated with said cup, each area being configurable from an original condition to a visibly different condition, wherein said plurality of distinct areas are depressible dimples, blisters, or other raised surfaces, and wherein depressing said distinct area configures said area to said visibly different condition and whereas each area provides a unique identifier. | 09-11-2008 |
20150014370 | DISPENSING CLOSURE AND SPOUT - A dispensing closure for a flowable product, the closure comprising means for causing a varying product discharge direction. | 01-15-2015 |
Mark J. Kiel, Ann Arbor, MI US
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20110143430 | HEMATOPOIETIC STEM CELL IDENTIFICATION AND ISOLATION - The present invention relates to methods of identifying, collecting and isolating hematopoietic stem cells (HSCs) and compositions of purified HSCs. Specifically, the present invention provides methods of isolating and purifying CD150 | 06-16-2011 |
20140030711 | METHODS AND BIOMARKERS FOR DETECTION OF LYMPHOMA - The present invention relates to methods and biomarkers for detection and characterization of lymphoma (e.g., splenic marginal zone lymphoma) in biological samples (e.g., tissue samples, blood samples, plasma samples, cell samples, serum samples). | 01-30-2014 |
20150050274 | METHODS AND BIOMARKERS FOR DETECTION AND TREATMENT OF MATURE T-CELL LEUKEMIA - The present invention relates to methods and biomarkers for detection and characterization of mature T-cell neoplasias/leukemias (e.g., T-cell prolymphocytic leukemia, Sezary syndrome) in biological samples (e.g., tissue samples, blood samples, plasma samples, cell samples, serum samples). | 02-19-2015 |
20150193578 | SYSTEMS AND METHODS FOR GENOMIC VARIANT ANALYSIS - A genomic variant analysis method and computer system utilizing information related to variant frequency and biological consequence to determine the relative statistical significance of each variant in given genome sequence datasets. The method and system perform both variant frequency normalization and universal pairwise variant comparisons across the given genome sequence datasets to automatically identify the likelihood of any given variant as contributing to disease process or biological phenomenon under study and organize the results into a priority ranking. The priority ranking is then used to categorize the results into biologically-related data subsets for display to indicate potential for importance. | 07-09-2015 |
Mark W. Kiel, Columbus, IN US
Patent application number | Description | Published |
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20140083074 | Crop Divider Hinge Kit and Method - Provided is a simple, inexpensive, truly feasible technical solution that readily permits do-it-yourself retrofitting of existing combine harvester heads to allow their crop dividers to pivot out of the way for transport. Provided is a retrofit hinge kit adapted for use with square tube frames and methods for its use. | 03-27-2014 |
20150047309 | Crop Divider Hinge Kit and Method - Provided is a crop divider hinge kit and method of installation and use that facilitates do-it-yourself retrofitting of existing combine harvester heads to allow their crop dividers to pivot out of the way for transport. Hinge kits may be adapted for use with frames having a square tube portion and may comprise a replacement portion of square tubing pivotably connected with a sleeve portion adapted to receive therein and be affixed to a cut portion of the square tube frame. Quick-disconnect fastening mechanisms may be used in connection with hinge kits, including in connection with removably fastening crop divider support members. | 02-19-2015 |
Taylor L. Kiel, El Paso, TX US
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20150130644 | LIGHTING SYSTEMS FOR LANDING IN A DEGRADED VISUAL ENVIRONMENT - Lighting systems and methods for landing in a degraded visual environment are disclosed. The lighting systems comprise one or more lighting units mounted to an aircraft operable to hover near a landing zone. Each lighting unit is operable to provide adjustable illumination to the landing zone, and has a radiant power output between a minimum and a maximum. The minimum radiant power output is just sufficient to allow a pilot to distinguish features in the landing zone when below a first altitude wherein the downwash from the aircraft rotors, propellers, or engines begins to raise particulates from the landing zone and continues to be just sufficient to allow the pilot to distinguish features as the pilot descends from the first altitude to termination at the landing zone, and the maximum radiant power output is less than about five times the minimum radiant power output. | 05-14-2015 |