Lewis, GB
Alan P. Lewis, Stevenage GB
Patent application number | Description | Published |
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20080262203 | NOVEL COMPOUNDS - The present invention relates to an antibody which has multiple specificities. In particular the antibody of the present invention binds to (cross react with) human IL-8, Gro-alpha, Gro-beta, Gro-gamma, and ENA-78. | 10-23-2008 |
20140010807 | NOVEL COMPOUNDS - The present invention relates to an antibody which has multiple specificities. In particular the antibody of the present invention binds to (cross react with) human IL-8, Gro-alpha, Gro-beta, Gro-gamma, and ENA-78. | 01-09-2014 |
Alan Peter Lewis, Stevenage GB
Patent application number | Description | Published |
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20090123479 | IMMUNOGLOBULINS - The present invention relates to antigen binding proteins to human IL-23, pharmaceutical formulations containing them and to the use of such antigen binding proteins in the treatment and/or prophylaxis of inflammatory diseases such as Rheumatoid Arthritis (RA). | 05-14-2009 |
20090162358 | ANTIGEN BINDING PROTEINS - Antigen binding proteins that bind β-amyloid peptide, in particular human β-amyloid peptide; methods of treating diseases or disorders characterised by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease and diseases or disorders affecting the eye or optic nerve characterised by elevated β-amyloid levels or β-amyloid deposits, including age related macular degeneration and glaucoma type diseases and β-amyloid dependent cataract formation, with said antigen binding proteins; pharmaceutical compositions comprising said antigen binding proteins; and methods of manufacture. | 06-25-2009 |
20100303821 | IMMUNOGLOBULINS - The present invention relates to antigen binding proteins to human IL-13, including anti-IL-13 antibodies and anti-IL-3/anti-IL-4 mAbdAbs, pharmaceutical formulations containing them and to the use of such antigen binding proteins in the treatment and/or prophylaxis of inflammatory diseases such as asthma or IPF. | 12-02-2010 |
20120128689 | ANTI-IL-23 IMMUNOGLOBULINS - The present invention relates to antigen binding proteins to human IL-23, pharmaceutical formulations containing them and to the use of such antigen binding proteins in the treatment and/or prophylaxis of inflammatory diseases such as Rheumatoid Arthritis (RA). | 05-24-2012 |
20120225055 | ANTIGEN BINDING PROTEINS - The present invention relates to antigen binding proteins, such as antibodies, which bind to serum amyloid P component (SAP), polynucleotides encoding such antigen binding proteins, pharmaceutical compositions comprising said antigen binding proteins and methods of manufacture. The present invention also concerns the use of such antigen binding proteins in the treatment or prophylaxis of diseases associated with amyloid deposition including systemic amyloidosis, local amyloidosis, Alzheimer's disease, and type 2 diabetes. | 09-06-2012 |
20120315267 | NOVEL USES - The present invention relates to antibodies which multiple antigen specificities and their use in treating human diseases | 12-13-2012 |
20130142788 | HUMANISED ANTIGEN BINDING PROTEINS TO MYOSTATIN6 - The present invention relates to humanised antigen binding proteins, such as antibodies, which bind to myostatin, polynucleotides encoding such antigen binding proteins, pharmaceutical compositions comprising said antigen binding proteins and methods of manufacture. The present invention also concerns the use of such humanised antigen binding proteins in the treatment or prophylaxis of diseases associated with any one or a combination of decreased muscle mass, muscle strength and muscle function. | 06-06-2013 |
20130310281 | NOVEL ANTIGEN BINDING PROTEINS - The present invention provides novel antigen-binding proteins derived from human germline V | 11-21-2013 |
20140105915 | BCMA (CD269/TNFRSF17) - BINDING PROTEINS - The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and APRIL to the BCMA receptor. Further disclosed are pharmaceutical compositions, screening and medical treatment methods. | 04-17-2014 |
20140147435 | NOGO-A Neutralizing Immunoglobulins for the Treatment of Neurological Diseases - The present invention relates to antibodies to NOGO, pharmaceutical formulations containing them and to the use of such antibodies in the treatment and/or prophylaxis of neurological diseases/disorders. | 05-29-2014 |
20140205604 | ANTIGEN BINDING CONSTRUCTS - The present invention is directed to antigen binding constructs comprising one or two epitope binding domains separated by a single chain Fc region of an antibody, wherein each epitope binding domain in capable of binding to VEGF, to dimers comprising two antigen binding constructs of the invention, pharmaceutical compositions comprising said dimers and their use in the treatment of diseases associated with VEGF signalling, such as diabetic macular edema (DME), wet age-related macular degeneration (Wet AMD). diabetic retinopathy, retinal vein occlusion (RVO), and corneal neovascularisation, and polynucleotide sequences encoding said antigen binding constructs. | 07-24-2014 |
Alan Peter Lewis, Hertfordshire GB
Patent application number | Description | Published |
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20100047243 | NOVEL ANTIBODIES AGAINST IGF-IR - The present invention relates to antibodies or antigen binding fragments thereof which specifically binds to IGF-1R, specifically hIGF-1R. Also disclosed are antibody preparations comprising antibodies or antigen binding fragments of the invention. Methods of producing such antibodies or antigen binding fragments and uses thereof are also included within the scope of the present invention. | 02-25-2010 |
20110014182 | ANTIGEN BINDING PROTEINS - Antigen binding proteins that bind β-amyloid peptide, in particular human β-amyloid peptide; methods of treating diseases or disorders characterised by elevated β-amyloid levels or β-amyloid deposits, particularly Alzheimer's disease and diseases or disorders affecting the eye or optic nerve characterised by elevated β-amyloid levels or β-amyloid deposits, including age related macular degeneration and glaucoma type diseases and β-amyloid dependent cataract formation, with said antigen binding proteins; pharmaceutical compositions comprising said antigen binding proteins; and methods of manufacture. | 01-20-2011 |
20110206686 | IL-23 ANTIBODIES - The present invention relates to antigen binding proteins to human IL-23, pharmaceutical formulations containing them and to the use of such antigen binding proteins in the treatment and/or prophylaxis of inflammatory diseases such as Rheumatoid Arthritis (RA). | 08-25-2011 |
20120070439 | ANTIGEN-BINDING PROTEINS - The invention relates to linkers suitable for use in antigen-binding proteins, certain antigen binding proteins and methods of making such proteins and uses thereof. | 03-22-2012 |
20120082682 | IL-13 BINDING PROTEIN - The present invention relates to antigen binding proteins to human IL-13, including anti-IL-13 antibodies and anti-IL-3/anti-IL-4 mAbdAbs, pharmaceutical formulations containing them and to the use of such antigen binding proteins in the treatment and/or prophylaxis of inflammatory diseases such as asthma or IPF. | 04-05-2012 |
Alan Peter Lewis, Stevenage Hertfordshire GB
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20110054149 | NOGO-A Neutralizing Immunoglobulins for the Treatment of Neurological Diseases - The present invention relates to antibodies to NOGO, pharmaceutical formulations containing them and to the use of such antibodies in the treatment and/or prophylaxis of neurological diseases/disorders. | 03-03-2011 |
Alastair Charles Lewis, York GB
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20110143952 | CHROMATOGRAPHIC DEVICE AND METHOD OF FABRICATION AND CHROMATOGRAPHIC METHODS - A chromatographic device for use in multi-dimensional GC is described having a gas flow channel means having an inlet and an outlet, and including a first length of tube defining a first stage and a second length of tube defining a second stage; wherein each of the first length of tube defining a first stage and second length of tube defining a second stage is microfabricated in the plane of a planar substrate layer such that each length of tube comprises a bore defining a closed curve in cross section. A GC assembly further comprising modulator, injector and detector and a method of fabrication of device and assembly are described. A method of analysing multi-dimensional GC data is described. | 06-16-2011 |
Andrew Lewis, Hampshire GB
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20100034132 | TELECOMMUNICATIONS SYSTEM AND METHOD - A telecommunications system for communicating data to and from a mobile device. The system comprises a plurality of repeater nodes disposed to form a network. Each repeater, node has a transceiver unit operable to transmit the data with a first transmission power to one or more other of the repeater nodes within one of a plurality of slots of a time frame. Each repeater node is allocated a time slot, and the mobile device is arranged to transmit and receive data to and from the repeater nodes in the network. Each of the repeater nodes is operable to transmit a pilot signal during the same one of the time slots of the time frame with a second transmission power, the second power being less than the first transmission power. The pilot signal includes an identifier of the repeater node which is transmitted with the pilot signal and the mobile device is operable to receive one of the pilot signals. | 02-11-2010 |
20100302993 | TELECOMMUNICATIONS SYSTEM AND METHOD - A telecommunications system, for communicating data to and from a mobile device. The system comprises a plurality of repeater nodes, each repeater node having a transceiver unit operable to transmit and receive data to or from one or more other of the repeater nodes or the control node or the mobile device within a predetermined range, and processing unit operable to control the transceiver unit. The system also comprises a control node operable to transmit data in a downstream direction from the control node to the mobile device via the repeater nodes and to receive data from the mobile device transmitted in an upstream direction from the mobile device to the control node via the repeater nodes. The control node, the mobile device and the plurality of repeater nodes are arranged to communicate the data in the downstream direction from the control node to the mobile device via the repeater nodes using a time frame divided into a plurality of time slots, and to communicate the data in the upstream direction from the mobile device to the control node via the repeater nodes using the time frame, and the time slots of the time frame are allocated to the repeater nodes to the effect that each repeater nodes transmits to another repeater node in one of the upstream or the downstream directions in a time slot which is a minimal time from the time slot in which the other repeater node transmits in the upstream or downstream direction. The telecommunications system reduces the time taken for upstream or downstream data to be transmitted from a mobile terminal within the network, via the repeater nodes to the control node. | 12-02-2010 |
20140029497 | TELECOMMUNICATIONS SYSTEM AND METHOD - A telecommunications system including a plurality of repeater nodes, each repeater node having a transceiver unit operable to transmit and receive data to or from one or more other of the repeater nodes or a control node or a mobile device within a predetermined range. The control node operable to transmit data to and receive data from the mobile device via the repeater nodes using a time frame divided into a plurality of time slots. The time slots of the time frame are allocated to the repeater nodes to the effect that each repeater node transmits to another repeater node in one of the upstream or the downstream directions in a time slot which is a minimal time from the time slot in which the other repeater node transmits in the upstream or downstream direction. | 01-30-2014 |
Andrew B. Lewis, Bristol GB
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20100220317 | Method and Apparatus for Acoustic Sensing Using Multiple Optical Pulses - An improved technique for acoustic sensing involves, in one embodiment, launching into a medium, a plurality of groups of pulse-modulated electromagnetic-waves. The frequency of electromagnetic waves in a pulse within a group differs from the frequency of the electromagnetic waves in another pulse within the group. The energy scattered by the medium is detected and, in one embodiment, the beat signal may be used to determine a characteristic of the environment of the medium. For example, if the medium is a buried optical fiber into which light pulses have been launched in accordance with the invention, the presence of acoustic waves within the region of the buried fiber can be detected | 09-02-2010 |
20100238429 | Method and Apparatus for Acoustic Sensing Using Multiple Optical Pulses - An improved technique for acoustic sensing involves, in one embodiment, launching into a medium, a plurality of groups of pulse-modulated electromagnetic-waves. The frequency of electromagnetic waves in a pulse within a group differs from the frequency of the electromagnetic waves in another pulse within the group. The energy scattered by the medium is detected and, in one embodiment, may be used to determine a characteristic of the environment of the medium. For example, if the medium is a buried optical fiber into which light pulses have been launched in accordance with the invention, the presence of acoustic waves within the region of the buried fiber can be detected | 09-23-2010 |
Andrew Lennard Lewis, Farnham GB
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20090022804 | CHEMOEMBOLISATION - A composition for chemoembolotherapy of solid tumours comprises particles of a water-insoluble water-swellable synthetic anionic polymer and, absorbed therein an anthracycline. Suitably the polymer is a poly(vinyl alcohol) based polymer and the drug is doxorubicin. | 01-22-2009 |
20110111036 | INTRACELLULAR ANTIBODY DELIVERY - The present invention concerns a composition comprising vesicles and encapsulated within the vesicles, an antibody, wherein the vesicles comprise an amphiphilic block copolymer having a hydrophilic and a hydrophobic block. | 05-12-2011 |
20110151013 | AMPHIPHILIC BLOCK COPOLYMERS FOR NUCLEIC ACID DELIVERY - The present invention provides a composition comprising vesicles and encapsulated within the vesicles, nucleic acid comprising less than 1000 nucleotides, wherein the vesicles comprise an amphiphilic block copolymer having a hydrophilic and a hydrophobic block. | 06-23-2011 |
20120269722 | CHEMOEMBOLISATION - A composition for chemoembolotherapy of solid tumours comprises particles of a water-insoluble water-swellable synthetic anionic polymer and, absorbed therein an anthracycline. Suitably the polymer is a poly(vinyl alcohol) based polymer and the drug is doxorubicin. | 10-25-2012 |
Andrew Lester Lewis, Nottingham GB
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20110172141 | PROCESS FOR PREPARING MICROPARTICLES - A process for preparing microparticles comprising a biologically active material and a polymer and having a mean particle size expressed as the volume mean diameter (VMD) of from 10 to 500 μm, wherein the biologically active material is substantially insoluble in the polymer, which process comprises: a. contacting a mixture of the biologically active material or a precursor thereof, the polymer or a precursor thereof and a processing aid with a supercritical fluid which is capable of swelling the polymer under temperature and pressure conditions necessary to maintain the fluid in a supercritical state; b. allowing the supercritical fluid to penetrate and liquefy the polymer, whilst maintaining the temperature and pressure conditions so that the fluid is maintained in a supercritical state; c. releasing the pressure to precipitate microparticles comprising the biologically active agent and the polymer. | 07-14-2011 |
20110257097 | PHARMACEUTICAL COMPOSITIONS OF SOMATOTROPHIC HORMONES - The invention provides a composition comprising (i) a somatotrophic hormone; (ii) a biodegradable polymer component; and (iii) a release modifier. A process for preparing, and the use of such a composition are also provided. | 10-20-2011 |
20140072588 | ABSORPTION OF THERAPEUTIC AGENTS ACROSS MUCOSAL MEMBRANES OR THE SKIN - Absorption of a therapeutic agent across a mucosal membrane or the skin can be enhanced using an absorption enhancer comprising a hydroxy fatty acid ester of polyethylene glycol. | 03-13-2014 |
Andrew Lester Lewis, Nottinghamshire GB
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20110171140 | ABSORPTION OF THERAPEUTIC AGENTS ACROSS MUCOSAL MEMBRANES OR THE SKIN - Absorption of a therapeutic agent across a mucosal membrane or the skin can be enhanced using an absorption enhancer comprising a hydroxy fatty acid ester of polyethylene glycol. | 07-14-2011 |
Brian Lewis, Upminster GB
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20090144518 | SYSTEM AND METHOD FOR STORAGE MANAGEMENT - A system and method for monitoring the storage estate of an organization using an interactive website that is configured to produce and display a novel set of key performance indicators (KPIs) related to the storage estate, including KPIs related to data collected from at least one of storage area network data and network attached storage data. In one embodiment, the novel set of KPIs includes one or more of protection efficiency, application efficiency, and snapshot overhead, where protection efficiency is calculated as a ratio of logical addressable data storage volume to total physical volume of data storage for storage area network data of the organization, application efficiency is calculated as a fraction of disk storage allocated to end user devices that is actually used by the end user devices for storage area network data, and snapshot overhead is calculated as a ratio of a volume of storage allocated for replicated copies of data to allocated storage for network attached storage data. | 06-04-2009 |
Carl Justin Lewis, Conwy GB
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20100263920 | Electrical device and method of manufacturing thereof - A three-dimensional circuit substrate comprises one or more electrically conductive tracks. The substrate is formed from a unitary moulding over the one or more electrically conductive tracks and thereby provides structural support therefor. | 10-21-2010 |
Caspar G. Lewis, Angus GB
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20090294131 | Christmas Tree and Wellhead Design - The device described herein combines a subsea wellhead and a tree mandrel into a single piece. The wellhead includes a tree valve block having an upper and lower section. The lower valve block section is integral with the wellhead and includes access between the production line and the tubing annulus to the main bore of the wellhead. | 12-03-2009 |
Christopher Mark Lewis, Rhondda Cynon Taff GB
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20110185483 | ARTICULATED BODY ARMOUR - A modular body armour system ( | 08-04-2011 |
20130133509 | Modular Emergency Stretcher System - A modular stretcher system includes a pouch having a releasable outer cover and an inner surface, and a stretcher comprised from a lightweight sheet material and stored within the pouch, wherein the stretcher is accessible upon release of the cover, and wherein the stretcher further includes at least two integrated load-bearing system fixings that engage the lightweight sheet and extend through the inner surface. The modular stretcher system may also be incorporated within a protective anti-ballistic jacket. | 05-30-2013 |
20130212791 | ARMOURED OVER-TROUSERS - Armoured over-trousers ( | 08-22-2013 |
Claire Lewis, Sheffield GB
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20090123366 | Targeted Therapy - In order to target a diseased material in a subject, a monocyte, or monocyte-derived cell, such as a macrophage, which incorporates a magnetic material, such as a magnetic particle or a ferrofluid, preferably having a biocompatible coating, is proposed to be administered. A magnetic energy source may then be applied to the subject to destroy, rupture or inactivate the diseased material. Alternatively, the monocyte or monocyte derived cell may additionally include a therapeutic agent, which is thereby targeted at the diseased material. | 05-14-2009 |
Clive Lewis, Rugby GB
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20100283318 | Marine power distribution and propulsion systems - A power distribution system that can be used in naval ships and submarines includes a first propulsion drive system including a propulsion motor having superconducting (preferably high temperature superconducting (HTS)) rotor windings and a power converter. A first propulsion power generation system supplies power to the first propulsion drive system and includes a generator having superconducting (preferably HTS) rotor windings and a power converter. A first power generation system includes a power source for supplying power to a first service distribution system that includes a dc distribution busbar (optionally implemented using HTS cabling or busbar) for carrying a distribution voltage and a distribution current, and a switchboard that includes protective switchgear with contacts. A power converter is used to connect the power source to the switchboard. The power converters are regulated according to a power source foldback and stabilizing characteristic. An electric load is supplied with power from a zonal power supply unit that forms part of a zonal power distribution sub-system. The electric load and the propulsion motor are regulated according to a load shedding and stabilizing characteristic. | 11-11-2010 |
David Lewis, Bristol GB
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20100284408 | SYSTEM FOR RECEIVING TRANSPORT STREAMS - A system comprising first input means for receiving a transport stream from an external source, second input means for receiving an input from a memory, means for connecting the first and second input means to an interface which is arranged to provide an output stream to a decoder. The second input means is arranged to provide an output to the interface in such a form that the interface does not distinguish between the output from the first and second input means. | 11-11-2010 |
David Andrew Lewis, Wiltshire GB
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20110182997 | SUSPENSION FORMULATIONS - The present invention relates to suspension formulations, especially those for delivering a pharmaceutically active agent in aerosol form using a spray or aerosol device, such as a pressurised metered dose inhaler (pMDI). The formulations may be for pulmonary, nasal, buccal or topical administration, but are preferably for pulmonary inhalation. | 07-28-2011 |
David Malcolm Lewis, Yorkshire GB
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20100224840 | Method and Composition - A method of treating a material to improve flame retardancy, the method comprising applying to the material urea, phosphorous acid or a salt thereof, and a base comprising a monovalent metallic cation. | 09-09-2010 |
20110041264 | HAIR TREATMENT COMPOSITION AND METHODS - wherein D is a chromophore; L is a linking group selected from SO | 02-24-2011 |
20110168202 | BLEACHING METHODS AND COMPOSITIONS - A method of treating a material, the method comprising applying to the material a composition comprising at least 10 wt % of ammonium carbonate, ammonium carbamate or a mixture thereof; and a source of hydrogen peroxide. | 07-14-2011 |
20110189116 | HAIR TREATMENT METHODS - A method of colouring a material, the method comprising the steps of: a)applying to the material a composition comprising a sulphur-containing nucleophile; and b)applying to the material a composition comprising a dye compound selected from a dye class other than the class of reactive dyes. | 08-04-2011 |
David Malcolm Lewis, West Yorkshire GB
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20080261003 | Improvements in and Relating to Image Articles - The invention relates to a method of manufacturing an image article comprising the steps of: | 10-23-2008 |
20090212554 | PRINTING - An image article comprises a substrate having a security image coated on at least a portion thereof, which security image effects less than 50% reflectance of radiation of a wavelength between 800 and 900 nm, wherein the security image comprises a defined infrared-absorbing compound, for example Pigment Green 8, wherein said infrared-absorbing compound does not create a strongly coloured security image. | 08-27-2009 |
20100059691 | Security Inks Containing Infrared Absorbing Metal Compounds - A composition comprising an ink and an infrared-absorbing material wherein said infrared-absorbing material comprises a metal, a metal salt, a metal oxide or metal nitride is described. Also described is an article comprising a substrate having imaged thereon an infrared-absorbing material to form a security image; and a method of manufacture of such an article said method comprising image-wise applying substrate a composition comprising an infrared-absorbing material. | 03-11-2010 |
20100233925 | Composition and Method - A flame-retardant composition comprising a first component selected from a phosphorous-containing acid or a salt of a phosphorous-containing acid and a second compound selected from an isocyanic acid, an isocyanic acid precursor, a cyanate salt, a thiocyanate salt or isothiocyanate precursor, dicyandiamide, cyanamide or carbodiimide precursor. | 09-16-2010 |
20140147576 | PRINTING - An image article comprises a substrate having a security image coated on at least a portion thereof, which security image effects less than 50% reflectance of radiation of a wavelength between 800 and 900 nm, wherein the security image comprises a defined infrared-absorbing compound, for example Pigment Green 8, wherein said infrared-absorbing compound does not create a strongly coloured security image. | 05-29-2014 |
David Malcolm Lewis, Otley GB
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20080282478 | Improvements in and Relating to Wool Treatment - A method of treating a wool material, the method comprising the steps of: | 11-20-2008 |
20110256081 | Hair Treatment Composition and Methods - In one embodiment, the invention provides a method of removing colour from dyed hair, the method comprising applying to the hair a colour removal composition comprising a sulfur-containing nucleophile or a precursor thereof. | 10-20-2011 |
20130133141 | COMPOSITION AND METHOD - A depilatory composition comprising a source of cyanate ion, an organic acid or a salt thereof and a peroxide compound; and methods of removing hair from the skin using such compositions. | 05-30-2013 |
20140190508 | METHOD - A method of removing colour from hair that has been oxidatively dyed, the method comprising the steps of: (a) contacting the hair with a composition comprising a sulfur-containing nucleophile or a precursor thereof; (b) contacting the hair with an acidic composition; and (c) contacting the hair with an oxidising composition; wherein there is no rinsing step between step (a) and step (b). | 07-10-2014 |
20150047131 | Hair Treatment Methods - A method of treating a material, the method comprising the steps of: (i) contacting the material with a colouring composition comprising a dye compound; and (ii) contacting the material with a composition comprising a quaternary ammonium salt. | 02-19-2015 |
20150068548 | Hair Treatment Methods - A colouring composition comprising: (i) at least 0.0001 wt % of a water-soluble dye compound containing one or more sulfonate and/or carboxylate groups; (ii) at least 0.1 wt % urea; (iii) from 0.1 to 2.5 wt % of a thiol; (iv) less than 0.5 wt % ammonia; and (v) less than 0.5 wt % sulfite ions. | 03-12-2015 |
David Owen Lewis, Warwickshire GB
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20100027989 | Network Protection Switching Mechanisms and Methods of Network Protection - A network protection switching mechanism comprises a plurality of optical switches located at a plurality of nodes; a plurality of optical communication paths between said switches; switch based fault detectors located as part of at least two switches which generate detection results representative of the identification of a fault; switch based controllers located as part of said at least two switches; and internal switch-communication means between said fault detectors and said controllers which facilitate the transmission of detection results from said fault detectors to said controllers; wherein said controllers directly cause switching to an alternative optical communication path dependent upon the receipt of said detection results; whereby autonomous switch based protection without dependence on either inter-switch control communication or higher level network control communication is achieved. | 02-04-2010 |
David Richard Lewis, Oxfordshire GB
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20090198344 | Metal Implants - An implant with a metal structure for use in a surgical procedure, in which at a region of the implant to be in contact with bone the metal structure is provided with a roughened surface. The roughened region is then provided with a ceramic coating comprising hydroxyapatite by a thermal spraying process. Biocidal ions of silver are absorbed into the ceramic coating, and gradually leach out into body fluids after implantation. The hydroxyapatite enhances bone regrowth into the implant, while the silver ions suppress infection. | 08-06-2009 |
20100136083 | Metal Implants - An implant with a metal structure for use in a surgical procedure, in which at least part of the metal structure is coated with a biocompatible metal such as titanium by plasma spraying of the metal powder. Biocidal metal cations are then absorbed by ion exchange into the coating, so that after being implanted the biocidal ions gradually leach out into the surrounding body fluids and suppress infection. The ion exchange properties of the coating may be modified by pretreatment with dilute phosphoric acid. | 06-03-2010 |
Edward Lloyd Lewis, Kent GB
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20110026559 | LASER DISPLAYS - A laser is provided, suitable for use in laser displays, having a laser cavity defined by at least first and second mirrors, a lasing material positioned in an optical path within the cavity with an associated pumping source and wherein one of the mirrors has a reflective surface that is moveable so as to alter the length of the cavity at a rate sufficiently high to ensure that effects due to a speckle pattern, as perceived by an observer or detector of light generated by the laser, are reduced while preserving the instantaneous coherence of the laser light. Sufficiently rapid movement of the mirror surface ensures that any speckle pattern changes at a faster rate than can be detected by the human eye or by a detector so that speckle is no longer visible, or is at least considerably reduced. | 02-03-2011 |
Elizabeth Amie Lewis, Hull GB
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20080267866 | Novel Antiviral Macrocycle Derivatives and Metal Complexes, Incorporating Bridged Macrocycles - A compound of Formulae (1), (2) or (3), A | 10-30-2008 |
Eric Anthony Lewis, Warwickshire GB
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20080231241 | Transformers - A multi-transformer unit is operative for converting an input AC voltage at a first voltage level to a net output AC voltage at a second voltage level. The multi-transformer unit can be used in place of a conventional transformer or an AC machine and is designed to suppress the transfer of harmonics between the input and output AC voltages. The unit comprises at least two phase-shifting transformers, each transformer being operative to provide a phase shift relative to the first voltage level. On the primary side of the unit the transformers are arranged for independent connection to the first voltage level, whereas on the secondary side of the unit the transformers are linked such that voltage vectors on the secondary side of the unit are added together to at least partially cancel the harmonic pollution and give the net output AC voltage. Moreover, the phase shift of the phase-shifting transformers may be selected to completely or substantially add into the net AC output voltage of the multi-transformer unit the fundamental voltage/frequency applied to its input AC voltage. | 09-25-2008 |
20130039106 | Controllers for Static Energy Supply Units - A static energy supply unit has an energy store 4-connected to an ac supply network by a power converter. A unit controller for the static energy supply unit includes an amplitude controller, a phase controller and a frequency controller. These measure and record characteristics of the supply network and provide output signals indicative of the voltage characteristics for an operating condition of the supply network. A signal generator for generating a simulated output voltage signal for each phase of the ac supply network is provided. A comparator is used to compare the simulated output voltage signal for each phase and a measured voltage for a corresponding phase of the supply network. The controller controls the operation of the power converter to vary the amount of power that is supplied to the supply network from the energy store 4-based on the comparison of the simulated output voltage signal(s) and the measured ac voltage(s). | 02-14-2013 |
20130093241 | CIRCUITS FOR DC ENERGY STORES - A dc energy store includes auxiliary systems operable in different modes, including self-supporting, island mode and normal modes. In the self-supporting mode a first controller uses a voltage demand signal indicative of desired ac voltage of an AC/DC power converter to control semiconductor power switching devices to achieve the desired level of ac voltage. The voltage demand signal is derived from comparing a voltage feedback signal and a second voltage demand signal preset to provide the desired ac voltage for the auxiliary systems. A second controller uses a current demand signal indicative of the desired dc link current to control the semiconductor power switching devices of a DC/DC power converter to achieve the desired level of dc link current. The current demand signal is derived from comparing a dc link voltage demand signal indicative of a desired dc link voltage and a dc link voltage feedback signal. | 04-18-2013 |
20130127391 | ELECTRICAL MACHINES - An ac synchronous electrical machine includes a stator and a multi-phase stator winding that defines a plurality of stator poles. The stator winding has two or more coil groups, each coil group including a plurality of coils for each phase that are received in winding slots in the stator. The stator winding is connected to a power source/sink. The coil groups are connected in series and each coil group is connected to a power source/sink by a respective switch ( | 05-23-2013 |
20130169045 | DC ENERGY STORE SYSTEMS AND METHODS OF OPERATING THE SAME - A dc energy store system includes a dc energy store, an AC/DC power converter having ac terminals connected to an ac power supply and dc terminals connected to the dc energy store, and at least one auxiliary unit associated with the dc enemy store. The dc energy store system is adapted to be operated in a number of different operating modes including: (i) a first mode to supply power from the ac power supply to the dc energy store; (ii) a second mode to supply power from the dc energy store to the ac power supply; (iii) a third mode to supply power from the ac power supply to the auxiliary unit(s); and (iv) a fault mode where there is a fault in the ac power supply, and power is supplied from the dc energy store to the auxiliary unit(s). | 07-04-2013 |
20130194704 | PROTECTION CIRCUITS AND METHODS FOR ELECTRICAL MACHINES - An assembly includes an electrical machine connected to a power converter by a three-phase circuit having three conductors, e.g. cables. Each conductor is associated with a switching device such as a contactor or the like that connects the conductor to a common conductor or terminal. In the event of a fault current being developed in the circuit or the power converter, the switching devices are operated to close the fault current and connect together the conductors or the three-phase circuit to provide a full three-phase short circuit. | 08-01-2013 |
20140145448 | MARINE PROPULSION SYSTEMS - A wind turbine generator has a drive end at which one or more turbine blades are mountable and a non-drive end. The wind turbine generator comprises an external stator having a radially inner surface and an internal rotor having a radially outer surface, an air gap being defined between the rotor and the stator. A main bearing arrangement is provided at the drive end and acts between the rotor and the stator to mount the rotor for rotation about the stator and a stabiliser bearing is provided at the non-drive end and acts between the rotor and the stator to stabilise the rotor and stator and maintain and control the air gap therebetween. | 05-29-2014 |
Gareth H. Lewis, Nailsea GB
Patent application number | Description | Published |
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20110088909 | STABPLATE CONNECTIONS - A stabplate connection is provided by: providing a first part ( | 04-21-2011 |
Gareth Michael Lewis, Essex GB
Patent application number | Description | Published |
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20100245202 | ANTENNA FEED MODULE - A feed module is provided for an array antenna. The feed module comprises a multi-layer printed circuit board (PCB) feed structure for coupling signals between connections to transmitters or receivers and connection points for connecting to antenna elements of the array antenna. The multi-layer PCB feed structure comprises a body portion, incorporating coupling components, and a number of line sections for connecting to elements of the array antenna. The planar layers of the multi-layer PCB are arranged to be mounted substantially perpendicular to a planar array of antenna elements of the array antenna when the feed module is integrated therewith. | 09-30-2010 |
20100277385 | PHASED ARRAY ANTENNA - Phased array antennas, in particular highly coupled arrays of dipoles having a vertical electrical feed structure. A phased array antenna including a plurality of antenna elements and a plurality of electrical feed structures, wherein each feed structure serves an antenna element and each electrical feed structure is at least partially substantially surrounded by a ferrite element. | 11-04-2010 |
Helen Lewis, Worcestershire GB
Patent application number | Description | Published |
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20090173084 | Storing device for chunks of water ice and method for providing chunks of water ice - The invention relates to a storing device for ice chunks that includes a receiving compartment for receiving therein ice chunks and a movable stirrer for effecting displacement of ice chunks received in the receiving compartment. The movable stirrer extends in the receiving compartment and rotates about a stirrer axis with the movable stirrer being disposed relative to the receiving compartment such that its stirrer axis extends through two surfaces of the receiving compartment. The movable stirrer is drivable in a stirring movement in a manner such that the movable stirrer effects displacement of the ice chunks with a substantial portion of the ice chunks not be advanced in a either a direction toward one of the two surfaces through which the stirrer axis extends of the other of the two surfaces through which the stirrer axis extends. | 07-09-2009 |
20090193824 | Ice-Making Machine - An ice maker comprises a tray, which has at least one automatically emptiable compartment for moulding a piece of ice, a storage chamber ( | 08-06-2009 |
20100011797 | REFRIGERATOR AND ICE RESERVOIR CONTAINER FOR IT - An ice reservoir container for a refrigerator is provided and includes a reservoir chamber which has a base that slopes along a first vertical section plane towards an outlet opening. The gradient of the base decreases along the section plane as the distance from the outlet opening increases. | 01-21-2010 |
20100024461 | REFRIGERATION DEVICE COMPRISING AN ICE DISPENSER, AND CORRESPONDING ASSEMBLY - A refrigeration device is provided that includes a housing enclosing an interior and an assembly in the interior having a storage compartment for chunks of ice and a stirrer. The stirrer is rotatable about an axis that extends through the storage compartment to move chunks of ice contained in the storage compartment in relation to each other and to move ice towards a dispensing passage that extends through the housing. A closable flap is interposed between the storage compartment and the dispensing passage. | 02-04-2010 |
20100025434 | Ice Dispenser - An ice dispenser including an ice supply container; a shaft extending into the supply container; a stirrer rotatable about the shaft which extends into the supply container, the stirrer being connectable to a rotation drive device that rotates the stirrer; an output chamber communicated with the supply container, the output chamber having an ice outlet opening; a slider rotatable in the output chamber, a rotation of the slider in a predetermined manner operating to bring the slider into moving engagement with ice located in the output chamber; and a coupling selectively disposable between an active coupling disposition in which the coupling operatively interconnects the stirrer and the slider to one another such that the slider rotates in correspondence with a rotation of the stirrer and a decoupling disposition in which the coupling does not operatively interconnect the stirrer and the slider to one another. | 02-04-2010 |
20100043477 | REFRIGERATION DEVICE COMPRISING AN ICE RESERVOIR - A refrigeration device is provided that includes a housing enclosing an interior and an ice reservoir, arranged in the interior, having an output opening and accommodating a stirrer. The ice reservoir can be pivoted between two positions that are different with respect to the height of the output opening. | 02-25-2010 |
Huw David Lewis, Sawbridgeworth GB
Patent application number | Description | Published |
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20080274476 | Assay Method - There is disclosed a method for determining the activity of gamma-secretase in a text subject, using a biological sample from the subject. | 11-06-2008 |
20090197904 | Sulphamides for Treatment of Cancer - Bridged bicyclic sulphamides of formula (I) are disclosed for treatment of cancer. | 08-06-2009 |
20090215775 | Sulphonamido-Substituted Cyclohexyl Sulphones for Treatment of Cancer - Compounds of formula (I) are disclosed for treatment of cancer. | 08-27-2009 |
20090306058 | Sulphone Derivatives for Treatment of Cancer - Compounds of Formula (I) are disclosed for treatment of cancer. | 12-10-2009 |
20100267801 | CYCLOHEXYL SULPHONES FOR TREATMENT OF CANCER - Sulphones of formula (I) are disclosed for use in treatment of cancer. | 10-21-2010 |
Ian Michael Lewis, Wallingford GB
Patent application number | Description | Published |
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20080279077 | Apparatus for and a method of enabling copying a copy-protected recording medium - Apparatus and methods are described to inhibit automatic installation of software by an installer carried on a recording medium so as to enable copying of content data from the recording medium. When the recording medium is inserted into a reader, an inhibitor inhibits an installer carried upon the recording medium from installing a copy protector by mimicking prior installation of the copy protector. | 11-13-2008 |
Jan Anthony Lewis, Caerphilly GB
Patent application number | Description | Published |
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20090144911 | Pressure relieving mattress - This invention relates to mattresses such as a pressure relieving mattress and in particular ones for profiling beds. The mattress comprises a base portion | 06-11-2009 |
Jane Lewis, Wellfied House Wales GB
Patent application number | Description | Published |
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20100149339 | METHOD FOR EVALUATING MECHANICAL TESTS OF A COATING - In a method for evaluating mechanical tests of a coating on a substrate, in a first step a mechanical stress is applied onto the coating, in a second step the substrate having the coating is isothermally clamped, in a third step an infrared photograph is generated of the region in which the mechanical stress is applied onto the coating in the first step, and in a fourth step the infrared photograph is evaluated. A device is arranged for carrying out the method. | 06-17-2010 |
Jane Lewis, Wellfield House Wales GB
Patent application number | Description | Published |
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20100328676 | METHOD FOR DETECTING IMPURITIES ON A SURFACE - A method is provided for detecting not fully set coatings and liquid or smearing impurities on a surface, in which in a first step a film is pressed onto a surface of a coating using a predefined press-on pressure, the film having a relative motion with respect to the surface of the coating, thereafter the film is pulled off the surface of the coating and finally it is determined whether impurities are adhering to the film. A device is also provided for performing the method, including at least one film, which may be pressed against a surface to be tested, at least one press-on roller having a surface by which the film is pressed against the coating, and at least one device for determining whether there are impurities adhering to the film. | 12-30-2010 |
Jason Lewis, Christchurch, Dorset GB
Patent application number | Description | Published |
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20110035097 | METHOD AND APPARATUS FOR DETERMINING A VALUE OF A ZERO POINT OFFSET OF A YAW RATE SENSOR - There is described a method for determining a value of a zero point offset of a yaw rate sensor. The method comprises measuring over time the output of the yaw rate sensor, determining whether the measured output has remained within a set of limits for a pre-determined period and if it is determined that the measured output has remained within the limits for the pre-determined period, using at least one measured value of the output to determine the value of the zero point offset. | 02-10-2011 |
Jason David Lewis, Dorset GB
Patent application number | Description | Published |
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20100114433 | Control System for Controlling a Motor Arrangement for Differentially Driving Left and Right Wheels of a Motorized Vehicle - A control system for controlling a motor arrangement for differentially driving left and right wheels of a motorized vehicle, the control system comprising: a comparator for receiving yaw rate sensor signals from a yaw rate sensor attached to the vehicle, the yaw rate sensor signals being indicative of actual yaw rates of the vehicle and for receiving yaw rate reference signals generated by a user input device, the yaw rate reference signals being indicative of user demanded yaw rates for the vehicle, the comparator arranged to output yaw rate error signals based on the difference between the yaw rate sensor signals and the yaw rate reference signals; a control loop for processing the yaw rate error signals to generate yaw rate correction signals for controlling the motor arrangement to reduce the yaw rate error signals, wherein the control loop comprises a variable limiter for limiting the yaw rate correction signals to values within a variable limit, the variable limit varying in dependence upon the yaw rate error signals. | 05-06-2010 |
Jeremy B. Lewis, Golders Green GB
Patent application number | Description | Published |
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20100181715 | DOCUMENT IMAGING SYSTEM AND METHOD - A document imaging system includes a document transport system that transports an original document through an imaging zone in optical communication with an image recording device. A document guide directs the original document toward the imaging zone and a document biasing device urges the trailing edge of the original document toward the document transport system. A printing system utilizing a document imaging system and a method of imaging an original document are also included. | 07-22-2010 |
Jeremy Brook Lewis, Golders Green GB
Patent application number | Description | Published |
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20090022521 | METHOD AND APPARATUS FOR CONTROLLING MULTIPLE COLOR DEVELOPERS USING A CAMMING MECHANISM - Aspects of this disclosure describe a multi-pass printer having a photoreceptor device mounted on an axis, a developer that is arranged adjacent to the photoreceptor device and is moving between a first portion and a second position, and a camming mechanism mounted on the axis that acts upon the developer to urge the developer between the firs and second positions. The camming mechanism can further include a camming disc that is mounted to rotate about the axis. The camming disc can also have an outer periphery edge having a first portion defined by a first radius and a second portion defined by a second radius. The camming mechanism can also have a developer roll spacing cam having an effective radius that maintains a spacing between the developer and the photoreceptor drum. | 01-22-2009 |
John Anthony Lewis, Caerphilly GB
Patent application number | Description | Published |
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20090295203 | Pressure Relieving Cushion - This invention relates to fluid filled sac suitable for use in or as a pressure relieving cushion and including a fluid containing channel structure formed so as to adopt a state when a user sits on the fluid filled sac in which the flow of fluid to the front of the fluid filled sac is prevented or inhibited. | 12-03-2009 |
John William Lewis, Winscombe GB
Patent application number | Description | Published |
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20100234412 | Buprenorphine Derivatives and Uses Thereof - Ester derivatives of the phenolic hydroxyl group of buprenorphine can be used in the treatment of opiate dependency and/or moderate to severe pain. The esters have an enhanced bioavailability, an enhanced duration of action, and a reduced abuse potential. | 09-16-2010 |
Katrina Lewis, Essex GB
Patent application number | Description | Published |
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20110192737 | APPARATUS AND METHOD FOR PRODUCING CUSTOMISED CONTAINERS OF CIGARETTES - Cigarettes are stored in one or more reservoirs at a customer location. A computer receives customer orders and transmits them to a dispenser. Upon receipt of a customer order, a pre-selected number of cigarettes is automatically removed from the reservoir(s) by the dispenser and then automatically packed in a container by a packer comprising a collation mandrel which is movable relative to the dispenser. A preferred type of substantially air-tight, self-sealing container has a lid portion, a body portion and a collar, which is mounted within the body portion. The body portion is provided with one or more upwardly extending protrusions on the upper surface of the base thereof. An air and moisture impermeable membrane is sealed about the upper periphery of the collar. | 08-11-2011 |
Keith L. Lewis, Malvern GB
Patent application number | Description | Published |
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20090095912 | CODED APERTURE IMAGING SYSTEM - This invention relates to coded aperture imaging apparatus and methods. In one aspect a coded aperture imager has at least one detector array and a reconfigurable coded aperture mask means. A reconfigurable coded aperture mask means can display various coded aperture masks to provide imaging across different fields of view and/or with different resolution without requiring any moving parts or bulky optical components. More than one detector array can be used to provide large area imaging without requiring seamless tiling and this represents another aspect of the invention. The present invention also relates to the use of coded aperture imaging in the visible, ultraviolet or infrared wavebands. The use of coded aperture imaging for imaging through a curved optical element is taught as the image decoding can automatically remove any aberrations introduced by the curved element. | 04-16-2009 |
Keith Loder Lewis, Malvern GB
Patent application number | Description | Published |
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20090052008 | OPTICAL MODULATOR - A micro-opto-electro-mechanical systems (MOEMS) electro optical modulator ( | 02-26-2009 |
Leo V. Lewis, Kenilworth GB
Patent application number | Description | Published |
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20080247863 | Sensor | 10-09-2008 |
20100209231 | COMBINATION OF MECHANICAL ACTUATOR AND CASE COOLING APPARATUS - A rotor blade tip clearance control apparatus for a gas turbine engine includes a plurality of circumferentially distributed segments which form an annular shroud surrounding the outer tips of a row of rotor blades. A mechanical arrangement is operatively connected to the segments. Actuation of the arrangement causes the segments to move in a radial direction thereby controlling a clearance between the segments and the outer tips. A case cooling system supplies cooling air to an engine case to which the segments are mounted. The cooling air regulates thermal expansion of the case and thereby also controls the clearance between the segments and the outer tips. | 08-19-2010 |
20110002771 | ROTOR BLADE OVER-TIP LEAKAGE CONTROL - A system is provided for controlling rotor blade over-tip leakage of a working fluid in rotating machine. The system has a circumferential row of rotor blades, and a circumferential row of seal segments for sealing with the radially outer tips of the rotor blades to reduce over-tip leakage of the working fluid. The seal segments have an inboard abradable layer which is adapted to be abraded by the blade tips to form a wear track for the blade tips. The system further has one or more tip wearing bodies which are adapted to wear down the blade tips. The thickness of the abradable layer and the cold build radial positions of the blade tips, seal segments and tip wearing bodies are arranged such that, during running-in of the machine, a wear track having a uniform radius is formed in the abradable layer by the blade tips, and the tip wearing bodies also wear down the blade tips to provide a uniform blade tip radius. | 01-06-2011 |
20110229306 | ROTOR BLADE TIP CLEARANCE CONTROL - A gas turbine engine has a row of circumferentially spaced rotor blades and a plurality of seal segments circumscribing the rotor blade tips and attached to a radially inward side of a casing of the engine. The seal segments are spaced from the casing by a spacing cavity. A flow of relatively hot cooling air is routed to the spacing cavity to cool the seal segments. The engine has an external cooling arrangement for impinging relatively cold cooling air on a radially outward side of the casing. The engine has a wall containing a plurality of through-holes which is attached to a radially inward side of the casing adjacent the seal segments. The wall is spaced from the casing to define a heating control chamber between the wall and the casing. The engine has one or more closable ducts which allow air to be exhausted from the heating control chamber. | 09-22-2011 |
20120022838 | SYSTEM CONTROL - A method of controlling a system that has a finite execution time in the optimisation of a cost function: | 01-26-2012 |
20120227414 | GAS TURBINE ENGINE SWIRLED COOLING AIR - A gas turbine engine has in flow series a compressor section, a combustor, and a turbine section. The engine includes a turbine section rotor disc, and a stationary wall forward of a front face or rearward of a rear face of the rotor disc. The wall defines a cavity between the stationary wall and the rotor disc, and has a plurality of air entry nozzles through which cooling air can be delivered into the cavity at an inlet swirl angle. The engine further includes a cooling air supply arrangement which accepts a flow of compressed air and supplies the compressed air to the nozzles for delivery into the cavity. The cooling air supply arrangement and the nozzles are configured such that the inlet swirl angle of the air delivered into the cavity can be varied between a first inlet swirl angle and a second inlet swirl angle. | 09-13-2012 |
Marcus Lewis, Herefordshire GB
Patent application number | Description | Published |
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20090097688 | AUDIO EQUIPMENT ATTACHABLE TO SPECTACLES - Audio equipment comprising a signal generating module ( | 04-16-2009 |
20110064255 | AUDIO EQUIPMENT - Audio equipment comprising a frame having a face and a pair of temples hingedly connected thereto, a conductor extending across the face to electrically connect audio modules associated with the temples, the face including grooves adapted to receive parts of lenses and a channel extending across a bridge region and interconnecting the grooves, the conductor extending through at least parts of the grooves and the channel. | 03-17-2011 |
Marcus Lewis, Glewstone GB
Patent application number | Description | Published |
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20110116673 | Wireless Personal Audio Equipment - A wireless personal audio equipment arrangement comprising: a hat, a control circuit including a microwave link receiver carried by the hat, the control circuit outputting signals to speakers, and acoustic chambers conducting sound signals produced by the speakers to earpieces carried by the hat. | 05-19-2011 |
Marcus Lewis, Cardiff GB
Patent application number | Description | Published |
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20090098913 | Hands-Free Kit for Mobile Radio-Telephone Handset - A hands-free kit for a mobile radio-telephone handset, the hands-free kit having an earpiece and an infra-red transmitter with the transmitter being able to relay audio signals from the handset to the earpiece. The earpiece includes an infra-red receiver for receiving audio signals from the transmitter. By positioning the transmitter in the line of sight of the earpiece receiver, audio signals may be relayed from the handset to the earpiece with the reduced likelihood of the earpiece becoming dislodged as the user moves his head. | 04-16-2009 |
Michael Vincent Lewis, Essex GB
Patent application number | Description | Published |
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20110192737 | APPARATUS AND METHOD FOR PRODUCING CUSTOMISED CONTAINERS OF CIGARETTES - Cigarettes are stored in one or more reservoirs at a customer location. A computer receives customer orders and transmits them to a dispenser. Upon receipt of a customer order, a pre-selected number of cigarettes is automatically removed from the reservoir(s) by the dispenser and then automatically packed in a container by a packer comprising a collation mandrel which is movable relative to the dispenser. A preferred type of substantially air-tight, self-sealing container has a lid portion, a body portion and a collar, which is mounted within the body portion. The body portion is provided with one or more upwardly extending protrusions on the upper surface of the base thereof. An air and moisture impermeable membrane is sealed about the upper periphery of the collar. | 08-11-2011 |
Oliver Lewis, Broxburn GB
Patent application number | Description | Published |
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20090074253 | Method and Apparatus for the Automatic Grading of Condition of Livestock - A method of and apparatus for grading a characteristic of an animal is described. The animal is guided to a detection area whereupon an image of the back of the animal is captured. Analysis of the image identifies anatomical points and determines angles at these points. The angles are then used to calculate a grading for a characteristic of the animal. An embodiment is presented for automating the determination of body score condition in dairy cows using seven angles determined at three anatomical points from an image over the back of the cow. | 03-19-2009 |
Richard G. Lewis, Weybridge GB
Patent application number | Description | Published |
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20090090499 | WELL SYSTEM AND METHOD FOR CONTROLLING THE PRODUCTION OF FLUIDS - Embodiments of the present invention allow the placement of a stand alone device (valve) along a flow path, without a physical connection to the surface or reliance on the borehole for signaling, to provide a means to control the flow between reservoirs. This is achieved using a valve located in the flow path that can be actuated without sending signals down the borehole or well path and thereby eliminating the need for complicated signal lines and or fluid columns to actuate the valve. | 04-09-2009 |
Richard Thomas Lewis, Bishops Stortford GB
Patent application number | Description | Published |
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20100029726 | CYCLOHEXANESULFONYL DERIVATIVES AS GLYT1 INHIBITORS TO TREAT SCHIZOPHRENIA - The present invention provides compounds of formula I: | 02-04-2010 |
Robert A. Lewis, Essex GB
Patent application number | Description | Published |
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20100171673 | DEPLOYABLE LENS ANTENNA - A deployable lens is provided for an antenna. The lens comprises an array of metallic lens elements formed on a plurality of planar sections of a dielectric substrate, each lens element comprising a first end-fire element directed towards a feed side of the lens, a second end-fire element directed towards a non-feed side of the lens and a section of transmission line for coupling signals between the first and second end-fire elements. The section of transmission line, preferably in the form of a slot-line transmission line, is integrated with the end-fire elements and is of a length determined according to the position of the lens element within the aperture of the lens as deployed. An antenna is also provided comprising a deployable lens according to the present invention. | 07-08-2010 |
Roger G. Lewis, Southampton GB
Patent application number | Description | Published |
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20110072310 | Diagnostic Data Capture in a Computing Environment - A method in a multithreaded computing environment for capturing diagnostic data, the method comprising the steps of: in response to a determination that the computing environment is in a predetermined invalid state, a first thread recording diagnostic data for the computing environment, wherein the determination includes a verification that the invalid state corresponds to a state other than a transient state of the computing environment corresponding to a transition of the computing environment by a second thread from a first valid state to a second valid state. An apparatus and computer program element for providing such diagnostic data capture are also provided. | 03-24-2011 |
20130013963 | DIAGNOSTIC DATA CAPTURE IN A COMPUTING ENVIRONMENT - A multithreaded computing environment for capturing diagnostic data includes initiating a trap delay component having a delay threshold in response to a monitor determining that the computing environment is in a predetermined invalid state. The multithreaded computing environment for capturing diagnostic data also includes recording, by a first thread, diagnostic data for the computing environment. The trap delay component delays the step of recording diagnostic data until the monitor determines that the predetermined invalid state has been repeated for at least one of a total count or a period corresponding to a predetermined indicator that it is a state other than a transient state of the computing environment. The transient state corresponds to a transition of the computing environment by one or more other threads from a first valid state to a second valid state. | 01-10-2013 |
Roger Gordon Lewis, Winchester GB
Patent application number | Description | Published |
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20100185903 | Failure Repetition Avoidance - Avoiding failure repetition in data processing includes storing a sequence of circumstances leading up to a previous failure, monitoring circumstances in a current process, matching a sequence of circumstances in the current process to a stored sequence of circumstances, and applying rules to determine if the current process should proceed. | 07-22-2010 |
Sarah Lewis, West Sussex GB
Patent application number | Description | Published |
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20100210641 | Organic Compounds - Compounds of formula I: in free or salt or solvate form, where R | 08-19-2010 |
Scott Alexander Lewis, Cambridge GB
Patent application number | Description | Published |
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20110186047 | Dry Powder Inhalers with Rotating Piercing Mechanisms and Related Devices and Methods - Dry powder inhalers with rotatable piercing mechanisms facilitate the use of dose container assemblies having dose containers arranged in concentric rows. A piercing mechanism is operably associated with the dose container assembly and is configured to pierce sealants that seal a dose container. The piercing mechanism is rotatable such that it can serially alternate between the two rows of dose containers. The piercing mechanism includes a rotatable drum, an elongate piercing member, and a biasing member operably associated with the piercing member. The rotatable drum has an open end, an opposite closed end, and a cylindrical wall that extends from the closed end and terminates at the open end. The closed end includes an aperture formed therein in a location adjacent to the wall. The elongate piercing member is extended and retracted through the aperture to pierce the sealants of a dose container. | 08-04-2011 |
20110226244 | DRY POWDER INHALERS WITH ENDLESS STRIPS AND COOPERATING PIERCERS AND RELATED METHODS - Dry powder inhalers are described with an inhaler body defining an enclosed cavity space and at least one of (a) an endless strip having opposing primary surfaces, the strip comprising a plurality of spaced apart blisters or dose containers holding dry powder medicament. The inhaler also has an inhalation exit flow path in the inhaler body in communication with at least one blister or at least one dose container held by the strip in a dispensing position and a piercer configured to release dry powder medicament from the blister or dose container in the dispensing position. | 09-22-2011 |
20120330152 | FLUID MANAGEMENT SYSTEM - The fluid management system according to the invention is adapted to automatically supply fluid for injection into a patient. The fluid management system comprises a fluid management device, a fluid transfer system and a fluid injector. The fluid management device serves to store and administrate multi dose containers. The fluid transfer system connects the outlet of the containers stored within the fluid management device to the injector and the injector withdraws the fluid via fluid transfer system from the containers and injects the fluid to an administration device at the patient. The fluid management device comprises at least one rotating carousel with the axis of rotation being vertically, at least two container holders attached to the rotating carousel, said container holders being adapted to position a container vertically with the open end of the neck facing downwards and a spike holder mounted below the rotating carousel and oriented such that the spike holder would axially align a spike connected to the spike holder with the axis of the container that is to be spiked and loaded into the container holder. | 12-27-2012 |
20130118490 | INHALERS WITH AIRWAY DISKS HAVING DISCRETE AIRWAY CHANNELS AND RELATED DISKS AND METHODS - Dry powder inhalers include radially-extending discrete, typically dose-specific, airway channels serially forming a portion of the inhalation pathway to deliver dry powder to a user using the inhalers. | 05-16-2013 |
20130133653 | DRY POWDER INHALERS WITH DUAL PIERCING MEMBERS - A dry powder inhaler includes a dose container assembly having a dose container disk with opposing upper and lower surfaces, a first row of circumferentially spaced apart dose containers at a first radius and a second row of circumferentially spaced apart dose containers at a second radius. The dose containers have dry powder therein and are sealed via a first flexible sealant over apertures in the upper surface and a second flexible sealant over apertures in the lower surface. A piercing mechanism includes two reciprocating piercers that serially alternate between the two rows of dose containers in the dose container disk. A rotatable ramp disk includes first and second sets of circumferentially spaced-apart ramp elements in staggered, concentric relationship that are configured to move the first and second piercing members between retracted and extended positions. | 05-30-2013 |
20140137864 | METHODS OF OPERATING AND FABRICATING INHALERS WITH AIRWAY DISKS HAVING DISCRETE AIRWAY CHANNELS - Methods of fabricating and operating dry powder inhalers that include dose disks and airway channel disks with sealant layers, the airway channel disks forming radially-extending discrete, typically dose-specific, airway channels serially forming a portion of the inhalation pathway to deliver dry powder to a user using the inhalers. | 05-22-2014 |
20140221936 | DEVICE FOR THE AUTOMATIC INJECTION OF TWO DOSES OF A MEDICAMENT - A device for the automatic injection of doses of a drug is described. The device has a slide and cam means, a syringe unit with a piston, and guide means. The axial movement of the slide initiated by a user by depressing its front end against an injection site, causes an angular displacement of the cam means that, in cooperation with the guide means, controls movement of the syringe piston and therefore administration of a drug dose. | 08-07-2014 |
20140257194 | DEVICE FOR AUTOMATIC INJECTION OF DRUG DOSES - A device for the automatic injection of doses of a drug compound is described. The device has a sliding sheath which, when depressed with its front end against the injection site, interacts with cam means to activate triggering of a plunger, thus controlling delivery of a drug dose. Plunger guide means are provided for controlling the triggering sequence and means for arming the device in the dose delivery condition. Automatic needle re-sheathing and resetting of a lock-out condition after each dose is delivered are also provided. | 09-11-2014 |
Simon John Lewis, Kent GB
Patent application number | Description | Published |
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20080275702 | System and method for providing digital dictation capabilities over a wireless device - A system and method for providing digital dictation capabilities over a wireless device. The system and method enables digital dictations to be recorded on a wireless device, such as a BlackBerry smartphone, and then uploaded wirelessly to a remote location, such a server, for transcription. Features of the wireless device, such as the display and trackball, can be used to control the dictation. | 11-06-2008 |
20090037434 | SYSTEM AND METHOD FOR EFFICIENTLY PROVIDING CONTENT OVER A THIN CLIENT NETWORK - A system, method and computer readable instructions for controlling streaming audio in real time in a thin client terminal server environment that can be used, for example, to provide support for a digital dictation system. A server runs client software, and at least one terminal runs a driver which communicates with the client software to create a virtual channel over which at least one digital dictation file is transmitted in packetized format between the terminal and the server, such that the client software controls operations performed at the terminal pertaining to the digital dictation file. | 02-05-2009 |
Simon Thomas Lewis, Gloucestershire GB
Patent application number | Description | Published |
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20080250748 | Joist Holder - A joist holder ( | 10-16-2008 |
Sion Marc Lewis, Buckinghamshire GB
Patent application number | Description | Published |
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20090317831 | Sepsis Test - There is provided a method for determining whether a subject has a bacterial infection comprising: identifying an abnormal expression of one or more of CD49e, CD 14, CD11c, CD49f, and CD29 on leucocytes in a sample obtained from the subject; wherein an abnormal expression of CD49e, CD 14, CD11c, CD49f or CD29 is indicative of the subject having a bacterial infection. | 12-24-2009 |
20120315653 | SEPSIS TEST - There is provided a method for determining whether a subject has a bacterial infection comprising: identifying an abnormal expression of one or more of CD49e, CD 14, CD11c, CD49f, and CD29 on leucocytes in a sample obtained from the subject; wherein an abnormal expression of CD49e, CD 14, CD11c, CD49f or CD29 is indicative of the subject having a bacterial infection. | 12-13-2012 |
Steffan Lewis, Muenchen GB
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20100124393 | SYSTEM FOR DELIVERING THE OUTPUT FROM AN OPTICAL FIBRE - A termination for an optical fibre is disclosed, including an end cap optically connected to a delivery end of the fibre and tapering its towards its proximal end so as to expand the signal beam output by the fibre, a capillary having a bore mounted so that the end cap and an end portion of the delivery fibre are mounted within the bore, the capillary having an end which is angled so as to reflect undesired radiation within the capillary away from the fibre, and a cladding mode stripper arranged upstream of the delivery end. | 05-20-2010 |
Steffan Lewis, Churchover GB
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20090251770 | CLADDING PUMPED FIBRE LASER WITH A HIGH DEGREE OF PUMP ISOLATION - An optical fibre laser or amplifier device is disclosed, comprising: a rare-earth-doped multi-clad optical fibre having at least three cladding layers, one or more multimode pump laser diodes, and a means of multiplexing a laser signal and the pumping radiation, adapted so that a fraction of the stray signal light originating within the device is captured by one of the intermediate cladding layers of the rare-earth-doped fibre and guided out of the laser structure through the multiplexing system resulting in a reduction in the amount of stray signal radiation impinging upon the pump laser diodes. | 10-08-2009 |
Steffan Lewis, Berkshire GB
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20090148098 | DEVICE FOR COUPLING RADIATION INTO OR OUT OF AN OPTICAL FIBRE - A device for coupling multimode pump light and a laser signal into or out of a cladding-pumped fibre laser is disclosed, comprising an output optical fibre, a substantially un-tapered feed-through optical fibre, an annular waveguide having a tapered section, and a plurality of multimode pump fibres such that: the signal feed-through fibre is located within the annular waveguide; the signal feed-through fibre is fused into the annular waveguide in the tapered section so that the annular waveguide becomes an additional cladding layer of the feed-through fibre; the end of the feed-through fibre that is fused into the annular waveguide is optically coupled to the output optical fibre; the multimode pump fibres are optically coupled to the annular waveguide in the un-tapered section. Methods of forming the device are also disclosed. | 06-11-2009 |
20090175301 | FIBRE LASER SYSTEM - A fibre laser system is disclosed comprising an optical fibre, a part of which is doped with a rare earth to form an optical gain medium; at least one laser diode; means for applying pump radiation from the laser diode to the optical gain medium and for generating a laser beam and delivery fibre means for delivering a laser beam to a workpiece, wherein the fibre laser is provided with at least one means for protecting one or more components from damage caused by errant radiation. Several different means of protection are disclosed. | 07-09-2009 |
Steffan Lewis, Reading GB
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20080219299 | OPTICAL FIBRE LASER - A fibre laser is disclosed comprising a single mode or low-order-mode cladding pumped fibre laser oscillator or preamplifier, a cladding pumped fibre laser power amplifier to guide multiple transverse modes, wherein an output from the oscillator or preamplifier is applied through a mode mixing means to the power amplifier. The laser power amplifier is of greater core and cladding diameter than the oscillator or preamplifier, thus enabling lower brightness pump sources to be employed. | 09-11-2008 |
20080219622 | OPTICAL FIBRE COUPLING SYSTEM - An optical fibre coupling structure comprising an optical fibre having an elongate input surface and shaped so that the diameter of the core of the fibre reduces in one dimension away from the input while increasing in the other dimension away from the input to form respective convergent and divergent surfaces, towards an output which is more circular than the input. | 09-11-2008 |
Stephen John Lewis, East Barnet GB
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20100016308 | Tetrahydroindole Derivatives for Treatment of Alzheimer's Disease - Tetrahydroindole derivatives of formula (I): are disclosed. These compounds modulate the activity of gamma-secretase and hence find use in treatment or prevention of Alzheimer's disease. | 01-21-2010 |
William David Lewis, Southampton GB
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20090288671 | Smoking Article Filter - A filter element having a longitudinally extending core and a wrapper ( | 11-26-2009 |
20090301503 | Method - A method of preparing a rod for use in the preparation of a smoking article is described. The rod has a first end and a second end. The rod has located therein a solid support. The solid support extends in a linear fashion from the first end of said rod to the second end of said rod. At least a portion of said solid support is coated and/or impregnated with an additive. The rod is prepared using rod forming means, wherein said rod forming means comprises a channel ending in an open exit, wherein material may pass through at least part of the channel and leave via the open exit in the form of a rod. The rod is prepared by: (i) providing starting material for forming said rod; (ii) providing the solid support for location within said formed rod; (iii) providing an additive for coating and/or impregnating at least a portion of said solid support; (iv) allowing said starting material to travel through at least part of said channel of said rod forming means; (v) coating and/or impregnating at least a portion of said solid support with said additive within said channel; (vi) allowing said solid support coated and/or impregnated with said additive to travel through at least part of channel of said rod forming means. The method comprises: (a) contacting a section of said starting material with a section of said solid support; wherein the initial contact of said section of starting material with said section of said solid support occurs in said rod forming means; (b) allowing the contacted sections of starting material and solid support to travel through at least part of said channel of said rod forming means in the direction of said open exit; (c) allowing the remainder of the starting material and the remainder of the solid support to contact in the rod forming means; (d) allowing the contacted remainder of the starting material and the solid support to travel through at least part of said channel of said rod forming means; (e) forming said rod by said rod forming means, such that on forming said rod said solid support extends within said rod from the first end of said rod to the second end of said rod; and (f) allowing said formed rod to exit from said open exit. | 12-10-2009 |
20130019886 | Method of Preparing a Rod for Use in the Preparation of a Smoking Article - A method of preparing a rod for use in the preparation of a smoking article is described. The rod has a first end and a second end. The rod has located therein a solid support. The solid support extends in a linear fashion from the first end of said rod to the second end of said rod. At least a portion of said solid support is coated and/or impregnated with an additive. The rod is prepared using rod forming means, wherein said rod forming means comprises a channel ending in an open exit, wherein material may pass through at least part of the channel and leave via the open exit in the form of a rod. | 01-24-2013 |