Shirota
Hidekazu Shirota, Rockville, MD US
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20130012922 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER - Methods for inducing an immune response to a tumor in a subject are disclosed herein. These methods include selecting a subject with a tumor and administering a therapeutically effective amount of apopototic tumor cells conjugated to a CpG oligodexoynucleotide (ODN) to the subject. In some embodiments, the CpG ODN is a K-type or a D-type CpG ODN. Methods for treating a tumor in a subject are also disclosed herein. These methods include selecting a subject with a tumor and administering a therapeutically effective amount of apopototic tumor cells conjugated to a CpG oligodexoynucleotide (ODN) to the subject. In some embodiments, the tumor cells are autologous. In additional embodiments, the tumor is a lymphoma, cervical cancer, prostate cancer, breast cancer, colon cancer or a lung cancer. | 01-10-2013 |
Hiroshi Shirota, Belmont, MA US
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20100279978 | METHODS OF REDUCING THE SEVERITY OF MUCOSITIS - The invention provides methods of reducing the severity of mucositis, involving administration of a toll-like receptor 4 antagonist. | 11-04-2010 |
20110144101 | MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS - The present invention provides methods for the use of compounds having formula (I) in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis, wherein R | 06-16-2011 |
20110201569 | Methods For Treating Myocardial Disorders - Provided are methods for treating myocardial disorders comprising administering to a subject an effective amount of a compound of formula (I) | 08-18-2011 |
20130196987 | MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS - The present invention provides compounds, methods for the synthesis thereof and methods for the use thereof in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis. | 08-01-2013 |
Yasutaka Shirota, Columbus, OH US
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20150280635 | DOOR OPENING/CLOSING CONTROL DEVICE - A door opening/closing control device includes: a controller controlling driving of an actuator opening or closing a door; a position detector detecting an opening/closing position of the door; a speed calculator calculating an opening/closing speed of the door based on a temporal change in the opening/closing position detected by the position detector; and a target assisting force calculator calculating target assisting force based on the opening/closing position and the opening/closing speed of the door. The controller controls the driving of the actuator to assist an operation of opening or closing the door based on the target assisting force calculated by the target assisting force calculator. Further, the controller controls the driving of the actuator such that the door is fully closed upon judgment that the opening/closing position of the door is in the vicinity of the fully closed position based on the opening/closing position detected by the position detector. | 10-01-2015 |