Ekaterina
Ekaterina Arikainen, Glasgow GB
Ekaterina Balabanova, Scarborough CA
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20150281321 | REAL-TIME EVENT MONITORING AND VIDEO SURVEILLANCE WEB APPLICATION BASED ON DATA PUSH - The present invention is directed to a method and system for providing real-time, web-based reactive user interface. In the method and system real-time updates are pushed directly to a web page of a web browser; the system further notifies a web browser that updates are available for retrieval. | 10-01-2015 |
Ekaterina Bobkova, Orlando, FL US
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20130245032 | BICYCLIC AND TRICYCLIC INHIBITORS OF SUMOYLATION ENZYMES AND METHODS OF THEIR USE - According to the embodiments described herein, a tricyclic SUMOylation inhibitor compound is provided. In some embodiments, a method for inhibiting a SUMOylation enzyme in a cell is provided. Such a method may include administering a SUMOylation inhibitor compound to the cell. In some aspects, the SUMOylation enzyme is SUMO E1 or SUMO E2. In some aspects, the method may be used to inhibit a cancer cell in vitro (e.g., grown in culture) or in vivo (e.g., as part of a tumor in a subject). In other embodiments, a method for treating a cancer, degenerative diseases and viral infection is provided. Such a method may include administering an effective amount of a pharmaceutical composition to a subject having the cancer. The pharmaceutical composition may include a SUMOylation inhibitor compound. In some embodiments, the method for treating a disease may further comprise administering one or more DNA-damaging therapy in combination with administration of the pharmaceutical composition. | 09-19-2013 |
20130317101 | SINGLETON INHIBITORS OF SUMOYLATION ENZYMES AND METHODS FOR THEIR USE - According to the embodiments described herein, a SUMOylation inhibitor compound comprising a singleton scaffold is provided. In some embodiments, a method for inhibiting a SUMOylation enzyme in a cell is provided. Such a method may include administering a SUMOylation inhibitor compound to the cell. In some aspects, the SUMOylation enzyme is SUMO E1 or SUMO E2. In some aspects, the method may be used to inhibit a cancer cell in vitro (e.g., grown in culture) or in vivo (e.g., as part of a tumor in a subject). In other embodiments, a method for treating a cancer, degenerative diseases and viral infection is provided. Such a method may include administering an effective amount of a pharmaceutical composition to a subject having the cancer. The pharmaceutical composition may include a singleton SUMOylation inhibitor compound. In some embodiments, the method for treating a cancer may further comprise administering one or more DNA-damaging therapy in combination with administration of the pharmaceutical composition. | 11-28-2013 |
Ekaterina Bocharova, Mulheim An Der Ruhr DE
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20150082636 | Method and Device for Producing Shaped Sheet Metal Parts at a Low Temperature - The invention relates to a method for producing a shaped sheet-metal part from a panel or a semifinished part made of a material consisting of steel with at least 60 wt. % Fe and a residual austenite content of at least 5%, in which the panel or the semifinished part is at least partially cooled to a temperature below −20° C. before the shaping and is shaped at a temperature below −20° C. in a forming tool. The object of providing a method for producing load-compliantly configured components, which on the one hand permits industrial-scale use of low-temperature forming and is configured particularly simply, is achieved by reducing the material temperature of the panel or semifinished part to below −20° C. is carried out in a thermally regulated cooling apparatus. | 03-26-2015 |
Ekaterina Bocharova, Duisburg DE
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20100273024 | DUAL-PHASE STEEL, FLAT PRODUCT MADE OF A DUAL-PHASE STEEL OF THIS TYPE AND PROCESSES FOR THE PRODUCTION OF A FLAT PRODUCT - A dual-phase steel, a flat product produced therefrom and a process for the production thereof. The dual-phase steel has, in addition to a strength of at least 950 MPa and good deformability, a surface finish which, when a simple production process is used, makes it possible for the flat product produced from this steel to be formed into a complexly formed component, such as a part of a car bodywork, in an uncoated state or in a state provided with an anti-corrosion coating. The steel according to the invention comprises 20-70% martensite, up to 8% retained austenite and the remainder ferrite and/or bainite and comprises (in % by weight): C: 0.10-0.20%, Si: 0.10-0.60%, Mn: 1.50-2.50%, Cr: 0.20-0.80%, Ti: 0.02-0.08%, B: <0.0020%, Mo: <0.25%, Al: <0.10%, P: ≦0.2%, S: ≦0.01%, N: ≦0.012%, the remainder iron and unavoidable impurities. | 10-28-2010 |
20110220252 | DUAL-PHASE STEEL, FLAT PRODUCT MADE OF SUCH A DUAL-PHASE STEEL AND PROCESS FOR THE PRODUCTION OF A FLAT PRODUCT - A dual-phase steel, a flat product and processes for the production thereof. The dual-phase steel having a strength of at least 950 MPa, good deformability, and good surface finish. It is possible, when a simple production process is used, for the flat product produced from this steel to be formed into a complexly formed component, such as part of a car body, either uncoated or provided with an anti-corrosion coating. The steel according to the invention has a structure comprising 20-70% martensite, up to 8% retained austenite and the remainder ferrite and/or bainite and has the following composition (in % by weight): C: 0.050-0.105%, Si: 0.20-0.60%, Mn: 2.10-2.80%, Cr: 0.20-0.80%, Ti: 0.02-0.10%, B: <0.0020%, Mo: <0.25%, Al: <0.10%, Cu: up to 0.20%, Ni: up to 0.10%, Ca: up to 0.005%, P: up to 0.2%, S: up to 0.01%, N: up to 0.012%, remainder iron and unavoidable impurities. | 09-15-2011 |
20130248055 | Multi-Phase Steel, Cold-Rolled Flat Product Produced from Such a Multi-Phase Steel and Method for Producing It - A multi-phase steel which in addition to iron and unavoidable impurities includes (in % wt.) C: 0.14-0.25%, Mn: 1.7-2.5%, Si: 1.4-2.0%, Al: <0.1%, Cr: <0.1%, Mo: <0.05%, Nb: 0.02-0.06%, S: up to 0.01%, P: up to 0.02%, N: up to 0.01% and optionally one of Ti, B, and V according to the following stipulation: Ti: ≦0.1%, B: ≦0.002%, V: ≦0.15%. A cast semi-finished product, is hot rolled starting at an initial temperature of 1100-1300° C. and ending at a final temperature of 820-950° C., coiled at 400-750° C., cold rolled into the cold flat product at degrees of 30-80%, and subjected to a heat treatment including continuous annealing at 20° C.+A | 09-26-2013 |
20130284321 | Multi-Phase Steel, Cold-Rolled Flat Product Produced from Such a Multi-Phase Steel and Method for Producing It - A multi-phase steel including in % wt. C: 0.14-0.25%, Mn: 1.7-2.5%, Si: 0.2-0.7%, Al: 0.5-1.5%, Cr: <0.1%, Mo: <0.05%, Nb: 0.02-0.06%, S: up to 0.01%, P: up to 0.02%, N: up to 0.01% and optionally at least one of Ti, B, and V according to the following stipulation: Ti: up to 0.1%, B: up to 0.002%, V: up to 0.15%, with the remainder iron and unavoidable impurities, wherein the microstructure has at least 10% vol. ferrite and at least 6% vol. residual austenite and the steel has a tensile strength R | 10-31-2013 |
Ekaterina Dadachova, Mahopac, NY US
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20080226548 | Methods of Applying Ionization Radiation for Therapy of Hiv Infection - This invention provides methods for treating subjects infected with human immunodeficiency virus (HIV) which comprise administering to the subjects a radiolabeled antibody or agent effective to kill HIV infected cells, where the antibody or agent is specific for a HIV envelope glycoprotein. The invention also provides compositions and methods for making compositions of radiolabeled antibodies or agents to HIV envelope glycoproteins for treatment of HIV infection. | 09-18-2008 |
20090328258 | Radiosynthesis as an Alternative Energy Utilization Process in Melanized Organisms and Uses Thereof - This present invention provides methods of enhancing the growth of a microorganism or plant by increasing its melanin content and exposing it to radiation, and methods of using melanized microorganisms to contain or exclude radiation. | 12-31-2009 |
20110300067 | METHODS FOR INCREASING EFFICACY OF RADIOIMMUNOTHERAPY OF MELANOMA - Methods are disclosed for using agents and treatments that cause the release of melanin from melanin-containing melanomas to increase the efficacy of therapy and imaging of the melanomas with radiolabeled anti-melanin antibodies and peptides. | 12-08-2011 |
20120003148 | RADIOIMMUNOTHERAPY AND IMAGING OF TUMOR CELLS THAT EXPRESS VIRAL ANTIGENS - Methods and compositions are provided for treating and imaging a virus-associated cancer, where the methods comprise administering to a subject a radiolabeled binding molecule, wherein the binding molecule binds to a virus antigen expressed by virus-associated cancer cells in the subject. | 01-05-2012 |
20120213697 | VERSATILE NANOPARTICULATE BIOMATERIAL FOR CONTROLLED DELIVERY AND/OR CONTAINMENT OF THERAPEUTIC AND DIAGNOSTIC MATERIAL - The invention provides compositions for controlled delivery and/or containment of therapeutic and/or diagnostic agents comprising the agent or agents encapsulated by a matrix containing chitosan, polyethylene glycol (PEG) and/or polyvinyl alcohol (PVA), and tetra-methoxy-ortho-silicate (TMOS) or tetra-ethoxy-ortho-silicate (TEOS), as well as methods for preparing the compositions, and uses of the compositions for therapy and imaging. | 08-23-2012 |
20140037674 | ORAL ADMINISTRATION OF MELANIN FOR PROTECTION AGAINST RADIATION - Methods and compositions are provided for alleviating and/or preventing one or more side effects associated with exposure to radiation in a subject exposed to radiation or at risk for exposure to radiation comprising oral administration to the subject of an amount of an edible source of melanin effective to alleviate a side effect associated with radiation. | 02-06-2014 |
20140044789 | MELANIN NANOSHELLS FOR PROTECTION AGAINST RADIATION AND ELECTRONIC PULSES - This invention provides melanin nanoshells and their use for protection against radiation, particularly ionizing radiation, and electronic pulses, and methods of making materials comprising melanin nanoshells. | 02-13-2014 |
20140147379 | RADIOBACTERIA FOR THERAPY OF CANCER - A method of treating a tumor in a subject, or reducing or preventing metastasis of a tumor in a subject, is provided comprising administering to the subject an amount of a bacteria labelled with, or comprising, one or more radionuclides so as to treat the tumor in the subject, or so as to reduce or prevent metastasis of the tumor in the subject. Radiobacteria-containing compositions and pharmaceutical compositions are also provided. | 05-29-2014 |
Ekaterina Dilks, Cambridge GB
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20130306729 | DEVICE FOR READING BARCODES - An image capture device for capturing an image of a test tube rack comprising a plurality of test tubes each having an individual barcode thereon, the image capture device comprising: an enclosure comprising a transparent window which, in use, is adjacent the test tube rack to be imaged; at least one camera mounted within the enclosure to capture an image through the window; a plurality of light sources mounted within the enclosure to illuminate the window and at least one light blocking element arranged to at least partially block light radiating from at least one of the plurality of light sources, wherein the plurality of light sources and the at least one light blocking element are arranged within the enclosure to provide generally uniform illumination across the whole window and to reduce unwanted reflections. | 11-21-2013 |
Ekaterina Doubrovina, West Orange, NJ US
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20150104413 | IMMUNOGENIC WT-1 PEPTIDES AND METHODS OF USE THEREOF - This invention provides peptides, immunogenic compositions and vaccines, and methods of treating, reducing the incidence of, and inducing immune responses to a WT-1-expressing cancer, comprising peptides derived from the WT-1 protein. | 04-16-2015 |
Ekaterina Dovgolevsky, Haifa IL
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20100273665 | CHEMICAL SENSORS BASED ON CUBIC NANOPARTICLES CAPPED WITH AN ORGANIC COATING - The present invention provides a sensor apparatus based on 2D films or 3D assemblies of cubic nanoparticles capped with an organic coating. The apparatus is used to determine the composition and preferably measure the concentration of volatile and non-volatile compounds in a sample, with very high sensitivity. Methods for use of the apparatus in applications such as diagnosis of disease, food quality and environmental control are disclosed. | 10-28-2010 |
20110015872 | CHEMICAL SENSORS BASED ON CUBIC NANOPARTICLES CAPPED WITH AN ORGANIC COATING FOR DETECTING EXPLOSIVES - The present application describes a sensor apparatus, especially an electronic nose, based on 2D films or 3D assemblies of cubic nanoparticles capped with an organic coating. The organic coating is modified with unique compositions of functional moieties, e.g. cyclodextrins, to provide the detection of volatile and non-volatile compounds derived from explosive materials, e.g. PETN, RDX, TNT etc. with very high sensitivity. The nose employs pattern recognition algorithms and methods, e.g. PCA, for detecting and quantifying specific explosive compounds. | 01-20-2011 |
Ekaterina Galanzha, Little Rock, AR US
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20120065490 | DEVICE AND METHOD FOR IN VIVO DETECTION OF CLOTS WITHIN CIRCULATORY VESSELS - A device and method of using the device to detect the presence and composition of clots and other target objects in a circulatory vessel of a living subject is described. In particular, devices and methods of detecting the presence and composition of clots and other target objects in a circulatory vessel of a living subject using in vivo photoacoustic flow cytometry techniques is described. | 03-15-2012 |
20150150463 | IN VIVO PHOTOACOUSTIC AND PHOTOTHERMAL NANO-THERANOSTICS OF BIOFILMS - A device and methods for the non-invasive manipulation and detection of target objects such as cells, pathogens, microparticles, and nanoparticles in vivo using an external magnetic field are described. In one aspect, a device and method for capturing and detecting intrinsically magnetic target objects or target objects labeled with at least one magnetic particle within the area of interest using an in vivo flow cytometer are described. | 06-04-2015 |
20150282716 | DEVICE AND METHOD FOR IN VIVO PHOTOACOUSTIC DIAGNOSIS AND PHOTOTHERMAL PURGING OF INFECTED BLOOD - A method of non-invasively detecting and purging bacterial cells using a modified photoacoustic in vivo flow cytometer device is described herein. In particular, a method of detecting bacterial cells by analyzing photoacoustic pulses emitted in response to laser pulses from a pulsed laser source and/or selectively destroying the detected bacterial cells using a non-linear photothermal response induced by a high-energy laser pulse is described herein. | 10-08-2015 |
20150335741 | IN VIVO PHOTOACOUSTIC AND PHOTOTHERMAL NANO-THERANOSTICS OF BIOFILMS - A composition and methods for the non-invasive destruction of bacteria cells in vivo using a combination therapy of antibiotics and photothermal nano-theranostics. In one aspect, a composition and method for destroying at least one bacteria cell using a functionalized PA contrast agent with a targeting agent, coating, and antibiotic that uses photoacoustic signals to create thermal energy and release the loaded antibiotic are described. | 11-26-2015 |
Ekaterina Gorelkina, Moscow RU
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20090293049 | METHOD FOR CONSTRUCTING DYNAMIC CALL GRAPH OF APPLICATION - A method of generating a dynamic call graph of an application is disclosed. The method includes collecting information on what program code pages are accessed during each sampling period, defining parts of an executable program code which are accessible during each sampling period according to the collected information, defining a set of functions within the defined parts of the executable program code, generating dynamic call graphs using the defined set of functions for each sampling period, and generating dynamic call graphs for an observation period by combining accurate dynamic call graphs of each sampling period. | 11-26-2009 |
Ekaterina Gresko, Zurich CH
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20120213801 | Phosphorylated Twist1 and cancer - The present application relates to methods for treating cancer in a subject by modulating the phosphorylation of the Serine 42 of Twist1 by administering to said subject a therapeutically effective amount of a modulator of said phosphorylation of the Serine 42 of Twist1. Antibodies, uses methods and biomarkers based on the phosphorylation of the Serine 42 of Twist1 are also provided. | 08-23-2012 |
Ekaterina Iakovleva, Orsay FR
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20140330127 | METHOD FOR RECONSTRUCTING THE GEOMETRY OF A SURFACE OF AN OBJECT VIA ECHOGRAPHIC PROBING, CORRESPONDING COMPUTER PROGRAM AND ULTRASOUND PROBING DEVICE - A method for reconstructing geometry of an object surface via echographic probing, using an ultrasound probe including plural transducers, the method including: controlling the transducers to transmit towards the surface ultrasound waves having initial transmission delays between them; executing at least once a cycle of operations including receiving from the transducers intermediate measurement signals, correcting transmission delays of the transducers using intermediate measurement signals, and controlling the transducers to transmit towards the surface ultrasound waves having the corrected transmission delays; receiving from the transducers final measurement signals resulting from reflection of a wavefront received simultaneously on the surface; determining specular travel times between each transducer and the surface based on the final measurement signals and the corrected transmission delays; and perform geometric reconstitution of the surface based on the determined specular travel times. | 11-06-2014 |
Ekaterina Iakovleva, Limours FR
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20150023136 | ULTRASOUND IMAGING METHOD AND DEVICE WITH PREDICTION OF ARTEFACTS INDUCED BETWEEN RECONSTRUCTION MODES - The invention relates to an ultrasound imaging method for imaging a part ( | 01-22-2015 |
Ekaterina Klimatcheva, Webster, NY US
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20140147447 | ANTI-CXCL13 ANTIBODIES AND METHODS OF USING THE SAME - Compositions and methods are provided for treating diseases associated with CXCL13 expression, including certain autoimmune diseases, inflammatory diseases, and cancers. In particular, anti-CXCL13 monoclonal antibodies have been developed to neutralize CXCL13. | 05-29-2014 |
20150050287 | ANTI-CXCL13 ANTIBODIES AND METHODS OF USING THE SAME - Compositions and methods are provided for treating diseases associated with CXCL13 expression, including certain autoimmune diseases, inflammatory diseases, and cancers. In particular, anti-CXCL13 monoclonal antibodies have been developed to neutralize CXCL13. | 02-19-2015 |
Ekaterina Kovacheva, Gardena, CA US
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20150233918 | Methods and Systems for Rapid Detection of Microorganisms using Free Antibodies - Disclosed herein are methods and systems for detection of a microorganism of interest using an amplification assay. The methods and systems utilize the specificity of binding agents, such as antibodies, to rapidly detect low levels of a specific microorganism present in a sample. In certain embodiments, antibodies are bound to a large number of the available binding sites on a microorganism. | 08-20-2015 |
Ekaterina Kuts, Tampere FI
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20090327968 | Apparatus and method for enabling user input - A method, apparatus, computer program and user interface wherein the method includes providing a plurality of selectable control elements where the plurality of selectable control elements are sorted into categories according to a first sorting criterion and sorted into positions within the categories according to a second sorting criterion; controlling a display to present a first one of the plurality of selectable control elements wherein the first one of the selectable control elements is positioned in a determined category at a determined position within the determined category; enabling a user to control the display to present a second one of the plurality of selectable control elements by enabling a first type of directional user input to select a different category and enabling a second type of directional user input to select a position within the selected category without changing the selected category. | 12-31-2009 |
Ekaterina Maidji, San Francisco, CA US
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20100304383 | BIOMARKERS FOR PRENATAL DIAGNOSIS OF CONGENITAL CYTOMEGALOVIRUS - The invention provides compositions and methods useful for early detection of congenital CMV infection, predicting the likelihood and severity of congenital CMV disease, and monitoring the efficacy of therapeutic approaches. Compositions of the present invention include biomarkers that are differentially expressed in CMV-infected mothers and fetuses compared to uninfected individuals. | 12-02-2010 |
Ekaterina Mikhaylichenko, San Jose, CA US
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20150090299 | PROCESSES AND APPARATUS FOR CLEANING, RINSING, AND DRYING SUBSTRATES - In some embodiments, a module is provided that is configured to clean, rinse and dry a substrate. The module includes (1) a tank having an upper tank region positioned above a lower tank region, the upper tank region having (a) an opening through which a substrate is removed from the tank; (b) a first fluid supply configured to supply a first fluid to a surface of a substrate being removed from the tank; and (c) a first suction mechanism, positioned below the first fluid supply, wherein the first suction mechanism is configured to suction fluid supplied from the first fluid supply so as to deter the suctioned fluid from reaching the lower tank region; and (2) a drying vapor supply positioned above the first fluid supply and configured to supply a drying vapor to a surface of a substrate being removed from the tank. Numerous other aspects are provided. | 04-02-2015 |
Ekaterina Mouradova, Victoria AU
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20110088125 | METHOD FOR PRODUCING TRANSGENIC SURFACE LAYER CHIMERIC PLANT - A rose is produced in which an introduced gene is only present in a part of the cells thereof, such as cells of the L1 layer of flower petals, but is not present in germ cells such as pollen cells or ovule cells. Since the introduced gene is not propagated to other roses even when this rose is crossed with other roses, the possibility of dispersal of the introduced gene can be completely negated. | 04-14-2011 |
Ekaterina Mouradova, Mill Park AU
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20120198589 | METHOD FOR PRODUCING TRANSGENIC SURFACE LAYER CHIMERIC PLANT - A rose is produced in which an introduced gene is only present in a part of the cells thereof, such as cells of the L1 layer of flower petals, but is not present in germ cells such as pollen cells or ovule cells. Since the introduced gene is not propagated to other roses even when this rose is crossed with other roses, the possibility of dispersal of the introduced gene can be completely negated. | 08-02-2012 |
Ekaterina Nesterenko, Dublin IE
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20120315023 | CAPILLARY COLUMN CURING SYSTEM - A curing system comprising an oven which may be usefully employed in the fabrication of long polymer columns of various morphologies and formats is described. In accordance with an exemplary arrangement the invention relates to a curing system comprising an oven that allows for the formation of very long capillary columns. | 12-13-2012 |
20120318782 | Column heater - A direct contact segmented column heater is described. The heater is capable of a broad heating and cooling range, and exhibits a very rapid response, with heating and cooling rates better than 350° C. min | 12-20-2012 |
Ekaterina Parshina, Moscow RU
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20090105395 | CURABLE RESIN COMPOSITION - The present invention is directed to a novel functional polyorganosiloxane having on average two or more vinyl groups in one molecule thereof. | 04-23-2009 |
Ekaterina Pestova, Glenview, IL US
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20120065085 | Detection of chromosomal abnormalities associated with endometrial cancer - The methods and compositions described herein address the need for diagnostic method that could be offered to women during yearly checkups to allow for early detection, diagnosis and classification, and treatment of endometrial cancer. In addition, these methods and compositons addresse the current need for improving diagnostic accuracy of biopsy procedures in symptomatic patients. | 03-15-2012 |
20120264635 | DETECTION OF CHROMOSOMAL ABNORMALITIES ASSOCIATED WITH PROGNOSIS OF NON SMALL CELL LUNG CANCER - The methods and compositions described herein address the need for a diagnostic method that can be provided to patients with early stage lung cancer, especially non-small cell lung cancer (NSCLC), to determine whether the patient is at increased risk of poor disease outcome. The methods and compositions thus allow for more informed treatment decisions for the early stage lung cancer patient. | 10-18-2012 |
20130149704 | MATERIALS AND METHODS FOR DIAGNOSIS OF MALIGNANT MELANOMA AND PROGNOSIS OF METASTASIS OF MALIGNANT MELANOMA - Methods, probes and kits for diagnosing malignant melanoma and prognosing metastasis thereof in a patient. | 06-13-2013 |
20130171638 | MATERIALS AND METHODS FOR DIAGNOSIS, PROGNOSIS AND ASSESSMENT OF THERAPEUTIC/PROPHYLACTIC TREATMENT OF PROSTATE CANCER - A method to detect prostate cancer comprising contacting a sample of prostate cells from the patient with a set of detectably labeled probes under hybridization conditions and determining the presence of chromosomal abnormalities in prostate tumor tissue, PIN (intra-epithelial neoplasia), histologically benign tissue and benign prostatic hyperplasia (BPH); a method to combine immunofluorescence and FISH (IF-FISH) to facilitate the assessment of chromosomal abnormalities; a set of probes; and a kit comprising the set of probes and instructions for diagnosing prostate cancer in a patient. | 07-04-2013 |
20130171639 | MATERIALS AND METHODS FOR DIAGNOSIS, PROGNOSIS, MONITORING OF RECURRENCE, AND ASSESSMENT OF THERAPEUTIC/PROPHYLACTIC TREATMENT OF PANCREATOBILIARY CANCER - A method of detecting high-grade dysplasia, pancreatobiliary cancer, or metastatic cancer to the pancreatobiliary tract or inferring an increased risk thereof, comprising obtaining a sample of pancreatobiliary cells from a patient with a set of detectably labeled probes comprising a locus-specific probe for MCL1 (myeloid cell leukemia sequence 1), a locus-specific probe for EGFR (epidermal growth factor receptor), a locus-specific probe for MYC, and a locus-specific probe for P16 under hybridization conditions and determining the presence of chromosomal abnormalities; a set of probes comprising a locus-specific probe for MCL1, a locus-specific probe for EGFR, a locus-specific probe for MYC, and a locus-specific probe for P16; and a kit comprising the set of probes and instructions for detecting high-grade dysplasia, pancreatobiliary cancer, or metastatic cancer to the pancreatobiliary tract, or inferring an increased risk thereof, in a patient. | 07-04-2013 |
20130237437 | NUCLEIC ACID HYBRIDIZATION PROBES - Compositions of nucleic acid hybridization probes for detecting a nucleic acid target sequence and methods for their production are described. In one preferred embodiment, the nucleic acid hybridization probe includes a hybridization domain, an adaptor, a linker, and a signaling domain. The hybridization domain includes a nucleic acid sequence having complementarity to the nucleic acid target sequence. The adaptor is a nucleic acid sequence. The linker includes a moiety having at least one abasic site, such that the moiety blocks extension by an elongating polymerase on a nucleic acid template containing the moiety. The signaling domain comprises a nucleic acid having at least one label or a nucleic acid having at least one nucleic acid domain for binding at least one additional nucleic acid. | 09-12-2013 |
20140031254 | DETECTION OF CHROMOSOMAL ABNORMALITIES ASSOCIATED WITH ENDOMETRIAL CANCER - The methods and compositions described herein address the need for diagnostic method that could be offered to women during yearly checkups to allow for early detection, diagnosis and classification, and treatment of endometrial cancer. In addition, these methods and compositions address the current need for improving diagnostic accuracy of biopsy procedures in symptomatic patients. | 01-30-2014 |
20140272963 | CELL PREPARATIONS AND CELL SUPPORTS AND THEIR USE IN THERANOSIS - A method of preparing cells from a patient specimen comprising a tissue or a clump of cells; a method of in situ hybridization (ISH) or immunohistochemistry (IHC); a method of theranosing a patient's response to an active agent that targets the tyrosine kinase pathway; an improvement of a method of theranosis comprising the method of ISH or IHC; a cell support on the surface of which are cells, which have been contacted with detectably labeled probes with the method of ISH or IHC; and a kit comprising (a) a cell support and/or at least one probe for ISH or IHC, and (b) instructions for carrying out the method of ISH or IHC on a cell support. | 09-18-2014 |
20140272969 | CELL PREPARATIONS AND CELL SUPPORTS AND THEIR USE IN THERANOSIS - A method of preparing cells from a patient specimen comprising a tissue or a clump of cells; a method of in situ hybridization (ISH) or immunohistochemistry (IHC); a method of theranosing a patient's response to an active agent that targets the tyrosine kinase pathway; an improvement of a method of theranosis comprising the method of ISH or IHC; a cell support on the surface of which are cells, which have been contacted with detectably labeled probes with the method of ISH or IHC; and a kit comprising (a) a cell support and/or at least one probe for ISH or IHC, and (b) instructions for carrying out the method of ISH or IHC on a cell support. | 09-18-2014 |
Ekaterina Pestova, Abbott Park, IL US
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20130171622 | COMPOSITIONS AND METHODS FOR DETECTING VIRAL INFECTION USING DIRECT-LABEL FLUORESCENCE IN SITU HYBRIDIZATION - The present invention relates generally to assays for the detection of viral infection and/or prognosis of viral infection and associated disease states. In particular, the invention relates to directly labeled viral-related nucleic acids having significant diagnostic, prognostic, and screening utilities and methods of using the same. | 07-04-2013 |
Ekaterina Pogosova, Tampere FI
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20130005395 | PROCESSOR ARRANGEMENT FOR MULTI-MODE WIRELESS DEVICE - A multi mode wireless device can communicate with cellular and non-cellular networks. The device has first and second processors in communication with each other. In one arrangement, the first processor provides control processing for physical layer 1 processing for both the cellular and the non-cellular radio communications in parallel, and the second processor provides processing for data link layer 2 for both the cellular and the non-cellular radio communications in parallel, and the device can communicate with the cellular and non-cellular networks simultaneously. In another arrangement, the first processor provides control processing for physical layer 1 processing for both the cellular and the non-cellular radio communications in parallel, and the second processor provides processing for data link layer 2 and all layers above layer 2 in the device for both the cellular and the non-cellular radio communications in parallel. | 01-03-2013 |
20130005396 | PROCESSOR ARRANGMENT FOR MULTI MODE WIRELESS DEVICE - A multi mode wireless device can communicate with cellular and non-cellular networks. The device has first and second processors in communication with each other. In one arrangement, the first processor provides control processing for physical layer 1 processing for both the cellular and the non-cellular radio communications in parallel, and the second processor provides processing for data link layer 2 for both the cellular and the non-cellular radio communications in parallel, and the device can communicate with the cellular and non-cellular networks simultaneously. In another arrangement, the first processor provides control processing for physical layer 1 processing for both the cellular and the non-cellular radio communications in parallel, and the second processor provides processing for data link layer 2 and all layers above layer 2 in the device for both the cellular and the non-cellular radio communications in parallel. | 01-03-2013 |
20140295828 | Methods and Apparatuses Enabling Selection Between Cellular and Non-Cellular Radio Connections - A modulator/demodulator apparatus obtains layer 1 measurements and/or estimations for cellular and non-cellular radio performance characteristics, and performs an evaluation based on at least the layer 1 measurements and/or estimations for selecting a connection to cellular or non-cellular radio. The apparatus provides information on results of the evaluation to a connection manager located in an upper layer, for performing a final decision on the connection to cellular or non-cellular radio, or obtains information supporting selection of a connection to cellular or non-cellular radio from the connection manager and performs a final decision on the connection to cellular or non-cellular radio based on results of the evaluation and the information from the connection manager for selecting the connection to cellular or non-cellular radio. | 10-02-2014 |
Ekaterina Protozanova, Arlington, MA US
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20120283955 | METHODS FOR DATA MANIPULATION RELATING TO POLYMER LINEAR ANALYSIS - The invention provides methods for the manipulation and processing of data from direct linear analysis of polymers such as nucleic acids. The resultant processed data is used to identify nucleic acids and/or their biological sources, and/or to identify mutations in the polymers. | 11-08-2012 |
20130288234 | DEVICE FOR PREPARING A SAMPLE - The invention provides a device for preparing a fluid sample, including but not limited to a sample comprising genomic DNA. | 10-31-2013 |
20140135489 | DEVICE FOR PREPARING A SAMPLE - The invention provides a device for preparing a fluid sample, including but not limited to a sample comprising genomic DNA. | 05-15-2014 |
20140295503 | METHODS AND DEVICES FOR BIOLOGICAL SAMPLE PREPARATION - Various aspects and embodiments of the present disclosure relate to methods of obtaining and manipulating nucleic acids from samples. In some embodiments, the samples are known to comprise or are suspected of comprising microorganisms such as bacteria and the methods of the invention are used to identify such microorganisms. | 10-02-2014 |
20150176058 | DEVICE FOR PREPARING A SAMPLE - The invention provides a device for preparing a fluid sample, including but not limited to a sample comprising genomic DNA. | 06-25-2015 |
Ekaterina Riabova, Lund SE
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20150377913 | DEVICE AND METHOD FOR DETERMINATION OF AN ANALYTE IN BLOOD - A sample acquiring device, an apparatus and a method for spectrophotometric measurement of high density lipoprotein (HDL) and at least one of total cholesterol (TC), triglycerides (TG) and glucose (FPG). | 12-31-2015 |
Ekaterina Rogers, Mountain View, CA US
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20150363835 | UTILIZING HEURISTIC BIDDING TO DETERMINE INVENTORY BID LANDSCAPE OF AN ACTIVE REAL-TIME DISPLAY CAMPAIGN - Systems and methods for determining a bid landscape for a content placement campaign are provided. A system identifies, for a content placement provider, serving parameters that define an inventory of content serving opportunities. The system creates bid buckets that have bid ranges. The system identifies a portion of the inventory to participate in bid discovery. The system selects, for each opportunity identified to participate, a bid value from within a bid bucket of the bid buckets. The bid value is provided as a bid for an auction to serve content in the opportunity. The system stores, for each of the identified content serving opportunities, the selected bid value and a result of the auction in which the selected bid value was provided as a bid. The system then determines an impression rate for each identified bid bucket and generates, from the determined impression rates, a bid landscape for the inventory. | 12-17-2015 |
Ekaterina Romanovskaya-Romanko, St. Petersburg RU
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20120164175 | NOVEL INFLUENZA VIRUS - The present invention provides a novel influenza virus wherein both the NS and the PB1 gene segments are modified and wherein the PB1-F2 open reading frame is modified by introduction of at least one stop codon. Specifically, the influenza virus is lacking functional NS1 and PB1-F2 proteins. | 06-28-2012 |
Ekaterina Ryjkina, Duesseldorf DE
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20120258306 | METHOD FOR GLUING FILM-LIKE SUBSTRATES - A method for adhesively bonding film-like substrates, in which a two-component polyurethane adhesive is applied to a film and then a second film is applied, a two-component polyurethane adhesive being used that consists of—a component A containing at least one prepolymer having at least two NCO groups,—a component B containing at least one polymeric or oligomeric crosslinker having at least two groups that react with NCO groups, wherein component B contains 0.05 to 5 wt. % of a low-molecular-weight compound C, which—should have a nucleophilic group that reacts with NCO groups and—contains a hydrogen-bridging group, selected from O═C—O | 10-11-2012 |
Ekaterina Rykhlinkskaya, Heidelberg DE
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20110320125 | METHOD FOR MARINE GEOELECTRICAL EXPLORATION WITH ELECTRICAL CURRENT FOCUSING - SUBSTANCE: Invention relates to marine geoelectrical exploration using controlled artificial sources of electromagnetic field. Using a dipole source, an electromagnetic field is generated inside the analysed medium by sending rectangular electric pulses with intervals in between into the medium. Geometrical probing is done along the profile during the current pulse, and probing on transient processes is done during the interval. Measurements are taken using measuring apparatus mounted on the seafloor, consisting of five electrodes: a central electrode with four others around it on corners of a square, two opposite sides of which are parallel to the axis of the profile. During the current flow period and intervals between current pulses, the second electric potential difference between external electrodes and the central electrode, as well as the first electric potential difference between three pairs of external electrodes is measured. When the dipole source passes through different points, there is provision for equipotentiality of a closed line passing through four external electrodes of the measuring apparatus thereby eliminating the horizontal component of current density in each probing point inside this line. Values of the measured electric potential differences are used to calculate three sets of standard interpreted electrical parameters which are not subject to lateral effect of three-dimensional geological non-uniformities located outside the probing point. Using the derived parameters, the model of the medium is found and time sections of this model is constructed on electroconductivity of elements of the medium, induced polarization coefficient and decay time constant of induced polarization potential differences. EFFECT: elimination of distorting lateral effect on probing results, which allows for deep sea delineation of hydrocarbon accumulation with high contrast. | 12-29-2011 |
Ekaterina Shamonina, London GB
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20120309316 | COMMON COMMUNICATIONS DEVICE - A common communications device comprising an array of near-field coupled resonant elements, the elements each comprising a coupling portion comprising a loop portion with free ends, the device being provided in combination with a data transmission unit and a data reception unit, each unit having a coupling portion, the units being arranged to communicate with one another by means of the coupling portion of each unit and the common communications device, the coupling portion of the data transmission unit comprising a resonant element comprising a loop portion arranged to be near-field coupled to the loop portion of a first resonant element of the device, the coupling portion of the data reception unit comprising a resonant element comprising a loop portion arranged to be near-field coupled to the loop portion of a second resonant element of the device not being the first resonant element. | 12-06-2012 |
Ekaterina Shatalova, Philadelphia, PA US
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20130217594 | METHODS FOR SCREENING COMPOUNDS FOR CAPABILITY TO INHIBIT PREMALIGNANT SQUAMOUS EPITHELIAL CELL PROGRESSION TO A MALIGNANT STATE - Methods for screening compounds for their capability to inhibit CYP1B1-mediated proliferation and motility of and/or to reverse estrogen-induced reduction in apoptosis of premalignant or malignant cells are provided. Kits for practicing the screening methods are also provided. | 08-22-2013 |
Ekaterina Shumilova, Perkasie, PA US
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20110229542 | METHODS FOR IMPARTING ANTI-MICROBIAL, MICROBICIDAL PROPERTIES TO FABRICS, YARNS AND FILAMENTS, AND FABRICS, YARNS AND FILAMENTS EMBODYING SUCH PROPERTIES - An antimicrobial fabric and method for treating fabric to impart antimicrobial properties thereto by preparing an aqueous solution of eugenol, polyvinyl alcohol, and glyoxal, padding the fabric with the aqueous solution to achieve a preselected desired part by weight wet pickup, drying the fabric; and curing the fabric. | 09-22-2011 |
Ekaterina Sinkevich, Enschede NL
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20120111012 | Ultra low emissions gas turbine combustor - The gaseous fuel-fired can combustor for a gas turbine include a generally cylindrical housing, and a generally cylindrical liner disposed coaxially within the housing to define with the housing a radial outer flow passage for combustion air, the-liner also defining inner combustion and a dilution zone, the dilution zone being axially distant a closed housing end relative to the combustion zone. A fuel/air mixing apparatus disposed at the closed housing end includes a plurality of swirl vanes defining passages each having constant cross-section flow areas along the vanes, and an increasing aspect ratio from the passage inlet to the outlet. An impingement cooling sleeve coaxially disposed in the combustion air passage between the housing and the liner cools the portion of the liner defining the combustion zone. Channeling apparatus is disposed between a downstream end region of the sleeve and the mixing apparatus and includes a diffuser section with a ratio of the outlet flow area to the inlet flow area in a range of 1.3-1.5. | 05-10-2012 |
Ekaterina Sizova, Huizen NL
Ekaterina Solntseva, Moscow RU
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20140081619 | Photography Recognition Translation - Methods are described for efficient and substantially instant recognition and translation of text in photographs. A user is able to select an area of interest for subsequent processing. Optical character recognition (OCR) may be performed on the wider area than that selected for determining the subject domain of the text. Translation to one or more target languages is performed. Manual corrections may be made at various stages of processing. Variations of translation are presented and made available for substitution of a word or expression in the target language. Translated text is made available for further uses or for immediate access. | 03-20-2014 |
20140081620 | Swiping Action for Displaying a Translation of a Textual Image - Disclosed is a method that involves acquiring an image with text, displaying all or a portion of the image on an electronic device. In response to detecting a swiping action or gesture, displaying a result of translation on a screen of the device. A first screen or display becomes a second one. Original text in a first language or source language may be easily and quickly compared to translated text shown on a second screen through a swiping gesture. Electronic dictionaries and machine translation may be used. These services may be independently stored and operated from different locations including on the device performing the translation, on a server or across a network (LAN, WAN, etc.). Optional manual correction of the translated text is also possible. | 03-20-2014 |
Ekaterina Suvorova, Hamden, CT US
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20150310005 | METHOD, SYSTEM AND SOFTWARE FOR SEARCHING, IDENTIFYING, RETRIEVING AND PRESENTING ELECTRONIC DOCUMENTS - The present invention provides a method and system for identifying, retrieving and presenting electronic documents responsive to user queries. The three distinct inventive concepts are relevancy ranking of responsive documents based on component query technique; cross-lingual searching; and search expansion using analytics of initial results to derive and generate a modified query. Each of these inventions enhances document search and retrieval systems and the three solutions may be used separately or in any combination. The three inventions apply in layers above an underlying search system, controlling the submission of requests to the underlying system in support of received search requests, typically originating with an end user. | 10-29-2015 |
20150310114 | METHOD, SYSTEM AND SOFTWARE FOR SEARCHING, IDENTIFYING, RETRIEVING AND PRESENTING ELECTRONIC DOCUMENTS - The present invention provides a method and system for identifying, retrieving and presenting electronic documents responsive to user queries. The three distinct inventive concepts are relevancy ranking of responsive documents based on component query technique; cross-lingual searching; and search expansion using analytics of initial results to derive and generate a modified query. Each of these inventions enhances document search and retrieval systems and the three solutions may be used separately or in any combination. The three inventions apply in layers above an underlying search system, controlling the submission of requests to the underlying system in support of received search requests, typically originating with an end user. Invention (I) involves use of focus-spectrum expanded search queries and either of two general types of enhanced OR operator that may be offered by the underlying search system. Processing of the content domain informs automated generation of elaborated queries using these operators for submitting to such an underlying system so as to yield improved relevance ranking | 10-29-2015 |
20150310115 | METHOD, SYSTEM AND SOFTWARE FOR SEARCHING, IDENTIFYING, RETRIEVING AND PRESENTING ELECTRONIC DOCUMENTS - The present invention provides a method and system for identifying, retrieving and presenting electronic documents responsive to user queries. The three distinct inventive concepts are relevancy ranking of responsive documents based on component query technique; cross-lingual searching; and search expansion using analytics of initial results to derive and generate a modified query. Each of these inventions enhances document search and retrieval systems and the three solutions may be used separately or in any combination. The three inventions apply in layers above an underlying search system, controlling the submission of requests to the underlying system in support of received search requests, typically originating with an end user. Invention (III) provides a semantic-expansion capability specifically utilizing the availability of language independent fields in the data being searched with natural language query terms. This invention is enhanced by incorporating the preceding two inventions. | 10-29-2015 |
Ekaterina Vaskova, Woodside, CA US
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20100238252 | Selective Heat-Transfer Imaging System and Method of Using The Same - A heat-transfer imaging system and a method of using the same. The heat-transfer imaging system includes a heat-transfer sheet and an activating ink. The heat-transfer sheet and the activating ink are specially formulated so that only the areas of the heat-transfer sheet onto which the ink has been printed become adhesive under heat-transfer conditions. This effect may be achieved by designing the sheet to include an ink-receptive coating whose melting temperature is higher than that typically encountered during normal heat-transfer conditions and by formulating the activating ink to include a plasticizer that, when printed onto the ink-receptive coating, lowers the melting temperature of the ink-receptive coating sufficiently so that the modified melting temperature falls within the temperature range encountered during heat-transfer. | 09-23-2010 |
20110104430 | Functional Micro- and/or Nano-Structure Bearing Constructions and/or Methods for Fabricating Same - A method is provided for fabricating a construction ( | 05-05-2011 |
20150283578 | Functional Micro- and/or Nano-Structure Bearing Constructions and/or Methods for Fabricating Same - A method is provided for fabricating a construction ( | 10-08-2015 |
Ekaterina Vert-Wong, Potomac, MD US
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20140271899 | METHOD OF ENHANCING THE BIODISTRIBUTION AND TISSUE TARGETING PROPERTIES OF THERAPEUTIC CECO2 PARTICLES VIA NANO-ENCAPSULATION AND COATING - The present invention provides methods and liposomal compositions useful in therapeutics, and diagnosis, prognosis, testing, screening, treatment and/or prevention of various disease conditions. The present invention provides imaging methods for various conditions. The present invention is a multi-layered drug delivery pathway, inclusive of nanoparticle liposomal formulations and mechanisms of localized action via unzipping upon delivery to the affected tissue site. The nano-encapsulation methodology allows maximization of a potent antioxidant's biocompatibility, increased target cell penetration and uptake, reduced off-target effects and retention of high anti-oxidative activity for promising therapeutic potential. | 09-18-2014 |
Ekaterina Volkova, Zurich CH
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20120221984 | METHOD OF OPTIMIZATION OF A MANUFACTURING PROCESS OF AN INTEGRATED CIRCUIT LAYOUT - A computer-implemented method, article of manufacture, and computer system for optimization of a manufacturing process of an integrated circuit or IC layout. The method includes: receiving input; organizing IC patterns; selecting IC patterns amongst the organized IC patterns; and optimizing a design of a manufacturing process of the IC layout based on the selected IC patterns. | 08-30-2012 |
20120324406 | METHOD OF OPTIMIZATION OF A MANUFACTURING PROCESS OF AN INTEGRATED CIRCUIT LAYOUT - A computer-implemented method, article of manufacture, and computer system for optimization of a manufacturing process of an integrated circuit or IC layout. The method includes: receiving input; organizing IC patterns; selecting IC patterns amongst the organized IC patterns; and optimizing a design of a manufacturing process of the IC layout based on the selected IC patterns. | 12-20-2012 |
Ekaterina Vorotelyak, Moscow RU
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20090148416 | ANGIOGENICALLY INDUCED TRANSPLANTS AND METHODS FOR THEIR USE AND MANUFACTURE - Angiogenically induced transplants and methods for their use and manufacture are disclosed. The angiogenic potential of the transplants is increased by contacting the transplants with donor mesenchymal cells such as hair follicle dermal papilla stem cells. Methods for treating disorders and diseases, such as disorders of the skin and angiopathies, are also disclosed. | 06-11-2009 |
Ekaterina Yurchuk, Dresden DE
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20140355328 | FERROELECTRIC MEMORY CELL FOR AN INTEGRATED CIRCUIT - An integrated circuit includes a ferroelectric memory cell. In one embodiment, the ferroelectric memory cell includes a first oxide storage layer, a second oxide storage layer, and an amorphous layer disposed between the first and second oxide storage layers. Each of the first and second oxide storage layers includes a ferroelectric material that is at least partially in a ferroelectric state and further includes, as main components, oxygen and any of the group consisting of Hf, Zr and (Hf,Zr). | 12-04-2014 |
Ekaterina Zavozina, Muehlhausen DE
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20120174068 | Testing Software Code - A computer-implemented method for testing software code includes the following steps performed by one or more processors: receiving a request to test at least a first portion of software code at a test framework, where the first portion of software code includes a dependency on a second portion of software code; marking the second portion of software code to indicate the dependency in the first portion of code; and replacing the second portion of software code with a third portion of software code during testing of the first portion of software code based on the marking of the second portion of software code. | 07-05-2012 |