Mercer
Alex Mercer, Bromma SE
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20080213276 | Modulation of neural stem cells and neural progenitor cells - The invention relates generally to methods of influencing central nervous system cells to produce progeny useful in the treatment of CNS disorders. More specifically, the invention includes methods of exposing a patient suffering from such a disorder to a reagent that modulates the proliferation, migration, differentiation and survival of central nervous system cells via S1P or LPA signaling. These methods are useful for reducing at least one symptom of the disorder. | 09-04-2008 |
20090232775 | Compounds and methods for increasing neurogenesis - The invention is directed to methods of promoting neurogenesis by contacting neuronal tissue with neurogenesis modulating agents. Novel methods for treating neurological disorders using neurogenesis modulating agents are disclosed. | 09-17-2009 |
20110189184 | MODULATION OF NEURAL STEM CELLS AND NEURAL PROGENITOR CELLS - The invention relates generally to methods of influencing central nervous system cells to produce progeny useful in the treatment of CNS disorders. More specifically, the invention includes methods of exposing a patient suffering from such a disorder to a reagent that modulates the proliferation, migration, differentiation and survival of central nervous system cells via S1P or LPA signaling. These methods are useful for reducing at least one symptom of the disorder. | 08-04-2011 |
Alex Mercer, Enskede SE
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20100129319 | TREATMENT OF DISEASE OR INJURY OF THE NERVOUS SYSTEM USING AGENTS THAT DECREASE THE ACTIVITY OF THE MELANOCORTIN 4 RECEPTOR - Novel methods are provided for modulating CNS cell neogenesis in the CNS cells in vitro or in vivo, involving the use of agents that decrease the activity of the melanocortin 4 receptor (MC4R). When the methods of the invention are applied to a subject such as a human, it may be used for reducing a symptom of a CNS disorder. | 05-27-2010 |
Andrew Allan Mercer, Dunedin NZ
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20130108704 | RECOMBINANT PROTEINS OF PARAPOXVIRUS OVIS AND PHARMACEUTICAL COMPOSITIONS THEREFROM | 05-02-2013 |
20130323201 | Combination Treatments and Compositions for Wound Healing - Viral VEGF and viral anti-inflammatory cytokine compositions, methods of treatment using them, and kits containing them for use in the promotion and/or improvement of wound healing and/or tissue repair, and for anti-scarring, anti-inflammatory, anti-fibrosis and anti-adhesion indications. | 12-05-2013 |
20140377297 | RECOMBINANT PROTEINS OF PARAPOXVIRUS OVIS AND PHARMACEUTICAL COMPOSITIONS THEREFROM - The invention relates to polynucleotides coding for the PPVO viral genome, to fragments of the polynucleotides coding for the PPVO genome and to polynucleotides coding for individual open reading frames (ORFs) of the PPVO viral genome. The invention also relates to recombinant proteins expressed from the above mentioned polynucleotides and to fragments of said recombinant proteins, and to the use of said recombinant proteins or fragments for the preparation of pharmaceutical compositions. | 12-25-2014 |
Augustus Mercer, Victoria CA
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20130267876 | STYLUS AND TREATMENT HEAD FOR USE WITH A MEDICAL DEVICE - A stylus and a treatment head for use with a medical device for imparting a force is provided. The stylus allows a practitioner to maintain focus on the treatment location while adjusting placement and force. This is because a light signal is emitted in the vicinity of the distal end of the stylus, proximate the treatment location on the patient. Alternatively, an audible or a tactile signal is employed for feedback. As a safety feature, the stylus is provided with means to allow it to collapse at forces above the accept able limit. | 10-10-2013 |
Augustus J. Mercer, Victoria CA
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20120312320 | METHOD AND HAIR CARE TOOL FOR DYNAMIC AND OPTIMUM HAIR STYLING TEMPERATURE CONTROL - Method and hair tool for styling hair, the hair tool having at least one heatable element, a temperature regulator associated with the heatable element to control the temperature of the heatable element, a temperature sensor for measuring the temperature of the heatable element, a compensation means operatively connected to the temperature regulator for compensating temperature drops or increases to which the heatable element is subjected when styling a hair lock. The hair tool further contains a programmable electronic control that controls operational features of the hair tool to implement a method of analyzing the hair lock and setting the hair tool to an optimal styling temperature calculated for the hair lock. | 12-13-2012 |
Christopher Paul Mercer, Western Australia AU
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20080199212 | Removably Mountable Frame For An Image Processsing Apparatus, A Removably Mountable Adaptor For An Image Processing Apparatus And Cartridges For Use With A Removably Frame And Removably Mountable Adaptor - A removably mountable frame comprising a driving force receiving means adapted to engage a driving force transmitting means of an image processing apparatus when the removably mountable frame is received within the image processing apparatus; and at least one frame driving force transmitting means, each frame driving force transmitting means adapted to co-axially engage corresponding cartridge driving force receiving means of a cartridge when the cartridge is engagedly received within the removably mountable frame, where the external configuration of the removably mountable frame when the cartridge is received therein is adapted to be received within the image processing apparatus and where the driving force receiving means is further adapted to transfer driving force applied thereto to each of the at least one frame driving force transmitting means. | 08-21-2008 |
Christopher Paul Mercer, Dongara AU
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20090263156 | PROCESS CARTRIDGE DETACHABLY MOUNTABLE TO AN IMAGE FORMING APPARATUS - A process cartridge comprising a photosensitive drum and at least one process member extending between two positioning members. In particular, the process cartridge is detachably mountable to an image forming apparatus. The a process cartridge is detachably mountable to an image forming apparatus, and contains a first positioning member, a second positioning member, a rotatable photosensitive drum extending between and connected to the first positioning member and second positioning member, and at least one process member extending between and connected to the first positioning member and second positioning member such that the distance between the rotatable photosensitive member and the process member is fixed by the first positioning member and the second positioning member. In a second embodiment, a housing member is adapted to contain toner, the housing member extending between the first and second positioning members such that any toner contained within is constrained directly by the first and second positioning members. | 10-22-2009 |
David Frederick Mercer, Edmonton CA
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20090151012 | Animal Model Having a Chimeric Human Liver and Susceptible to Human Hepatitis C Virus Infection - The present invention features a non-human animal model that is susceptible to infection by human hepatotrophic pathogens, particularly human hepatitis C virus (HCV). The model is based on a non-human, immunocompromised transgenic animal having a human-mouse chimeric liver, where the transgene provides for expression of a urokinase-type plasminogen activator in the liver. The invention also features methods for identifying candidate therapeutic agents, e.g., agents having antiviral activity against HCV infection. The animals of the invention are also useful in assessing toxicity of various agents, as well as the activity of agents in decreasing blood lipids. | 06-11-2009 |
20110167507 | Animal Model Having a Chimeric Human Liver and Suceptible to Human Hepatitis C Virus Infection - The present invention features a non-human animal model that is susceptible to infection by human hepatotrophic pathogens, particularly human hepatitis C virus (HCV). The model is based on a non-human, immunocompromised transgenic animal having a human-mouse chimeric liver, where the transgene provides for expression of a urokinase-type plasminogen activator in the liver. The invention also features methods for identifying candidate therapeutic agents, e.g., agents having antiviral activity against HCV infection. The animals of the invention are also useful in assessing toxicity of various agents, as well as the activity of agents in decreasing blood lipids. | 07-07-2011 |
20120309032 | Animal Model Having a Chimeric Human Liver and Suceptible to Human Hepatitis C Virus Infection - The present invention features a non-human animal model that is susceptible to infection by human hepatotrophic pathogens, particularly human hepatitis C virus (HCV). The model is based on a non-human, immunocompromised transgenic animal having a human-mouse chimeric liver, where the transgene provides for expression of a urokinase-type plasminogen activator in the liver. The invention also features methods for identifying candidate therapeutic agents, e.g., agents having antiviral activity against HCV infection. The animals of the invention are also useful in assessing toxicity of various agents, as well as the activity of agents in decreasing blood lipids. | 12-06-2012 |
Ian Petar Mercer, County Wicklow IE
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20110075150 | Apparatus and method for sample analysis - Prior art coherent optical wave mixing has permitted two-dimensional maps from which coupled quantum transitions have been identified in molecular samples. However, extended signal accumulation times and computer processing are required for a detailed molecular analysis, which can lead to sample toxicity and difficulties in interpretation. These and other requirements are reduced by an apparatus arranged for the projection of an image that directly encodes quantum couplings from a sample. Such an apparatus includes a source component ( | 03-31-2011 |
James Mercer, Shearstown CA
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20090056522 | Support device for a guitar or other musical instrument - A device for supporting a musical instrument such as a guitar, on a stand, comprising, a first engagement means adapted to engage with and support the musical instrument, a first strap adapted to releaseably engage with the musical instrument and in engagement with the first engagement means, and means for securely and releasably engaging the first engagement means to the stand. | 03-05-2009 |
Jason Mercer, Zurich CH
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20100272706 | ANTIVIRALS - This invention provides methods for inhibiting or treating infection by viruses, in particular pox viruses by modulating a kinase, in particular by inhibiting a host cell kinase, involved in mediating viral infection. Methods to identify, validate, and classify the cellular proteins required by viruses during infection of host cells in order to select agents which can inhibit viral infection are described herein. Using a systems biology approach the virus/host cell interaction is studied from initial attachment of the incoming virus to the cell surface, to entry, transcription, replication, biosynthesis, and assembly of progeny particles. The method employs a siRNA screening platform and uses gene silencing to map the ‘viral infectome’—a compilation of cellular proteins that the virus needs to establish infection and drive the infectious cycle. Charting the infectome provides information on the viral biology by the identification of host cell proteins involved in viral infection and allows the development of novel anti-viral drugs that prevent the viruses from establishing productive infection in cells. | 10-28-2010 |
John Mercer, Evans Head AU
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20100086351 | Dowel sleeves - A dowel sleeve has a tubular body with a mounting assembly at one end for releasable connection to a construction plate, and a leg support engagable at the other end for adjustable support. The construction plate has spaced non-circular holes. A first flange of the mounting assembly has a complementary profile, of smaller dimensions, to the non-circular holes, while a second flange has a similar profile, of larger dimensions, with its major-axis non-aligned with the major-axis of the first flange. The first flange is inserted through one of the non-circular holes, and the tubular body is rotated so the first and second flanges engage opposed faces of the construction plate. | 04-08-2010 |
20110255920 | Dowel sleeves - A dowel sleeve has a tubular body with a mounting assembly at one end for releasable connection to a construction plate, and a leg support engagable at the other end for adjustable support. The construction plate has spaced non-circular holes. A first flange of the mounting assembly has a complementary profile, of smaller dimensions, to the non-circular holes, while a second flange has a similar profile, of larger dimensions, with its major-axis non-aligned with the major-axis of the first flange. The first flange is inserted through one of the non-circular holes, and the tubular body is rotated so the first and second flanges engage opposed faces of the construction plate. | 10-20-2011 |
John Mercer, Edmonton CA
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20100290988 | FLUORINATED FRUCTOSE DERIVATIVES FOR PET IMAGING - The present invention is directed to fructose-based radiopharmaceuticals, pharmaceutical compositions comprising same, precursors and methods for preparing same, and methods of using same for diagnostic imaging of cancer cells and non-imaging tracer studies. | 11-18-2010 |
20130078184 | FLUORINATED FRUCTOSE DERIVATIVES FOR PET IMAGING - The present invention is directed to fructose-based radiopharmaceuticals, pharmaceutical compositions comprising same, precursors and methods for preparing same, and methods of using same for diagnostic imaging of cancer cells and non-imaging tracer studies. | 03-28-2013 |
Larry Mercer, Doha QA
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20120125631 | Systems and Methods of Diverting Fluids In A Wellbore Using Destructible Plugs - A bridge plug arrangement includes a plug having an upper end and a bottom end. The bridge plug arrangement also optionally includes a cylindrical seat. The bridge plug arrangement further includes a tubular member. The tubular member may be part of a casing string. The tubular member is configured to receive the plug and, when used, the seat. The plug and/or the seat may be fabricated from a frangible material. A method for diverting fluids in a wellbore using the bridge plug arrangement is also provided. The method may include landing the plug onto the seat within the wellbore below a subsurface zone of interest. Treatment fluids are then injected into the wellbore, where they are diverted through perforations and into a formation. The plug and/or seat is then optionally broken into a plurality of pieces through use of a downward mechanical force. | 05-24-2012 |
Luciana V. Mercer, Sao Paulo-Sp BR
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20130123731 | Absorbent Personal Care Article Having Intermeshing Flaps - An absorbent personal care article, such as a sanitary napkin or incontinence pad, having a longitudinal centerline and a transverse centerline and including a pair of opposed first and second wings extending along the longitudinal sides of the article. The first wing includes two or more peaks with furrows there between and the second wing includes one or more peaks. The peaks of the first and second wings are sized and positioned on the article such that when folded under the article and around the wearer's undergarments, the peak of the second wing extends across the longitudinal centerline of the article and into the furrow of the first wing. The inter-meshing wings help wearer's properly don the articles, improve the attachment of the article to the wearer's garment and/or reduce unwanted twisting or bunching of the article during use. | 05-16-2013 |
Nathan Zachary Mercer, Calgary CA
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20140267250 | METHOD AND APPARATUS FOR DIGITAL ELEVATION MODEL SYSTEMATIC ERROR CORRECTION AND FUSION - A system and method for generating a corrected digital elevation model is configured to remove systematic errors from digital elevation models. A residual dataset that is the difference between a first digital elevation model and a second digital elevation model is obtained and at least one error pattern related to a systematic error is identified. An error model representing at least one error pattern is generated and then removed from the first digital elevation model to create the corrected digital elevation model. | 09-18-2014 |
Richard Mercer, Ecully FR
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20120172383 | FUNGICIDAL COMPOSITIONS BASED ON PYRIDYLMETHYLBENZAMIDE DERIVATIVES AND AT LEAST ONE COMPLEX III INHIBITING COMPOUND - 1) Fungicidal compositions comprising: a) at least one pyridylmethylbenzamide derivative of Formula (I), in which the various radicals are as defined in the description; and b) at least one compound (II) capable of inhibiting the transport of electrons of the respiratory chain of mitochondrial ubiquinol:ferricytochrome-c oxidoreductase or complex III in phytopathogenic fungal organisms. 2) Process for curatively or preventively controlling the phytopathogenic fungi of crops, characterized in that an effective and nonphytotoxic quantity of one of these fungicidal compositions is applied to the aerial parts of plants. | 07-05-2012 |
Ronald G. Mercer, Mississauga CA
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20140369200 | DISABLING HEADER COMPRESSION OVER POINT-TO-POINT PROTOCOL (PPP) - A system and method for disabling header compression during an establishment and configuration of a communication protocol and communication channel between a pair of correspondents. The system comprises an initiating correspondent transmitting at least one PPP negotiation packet having at least one acceptable TCP/IP header compression option type. A software module of a responding correspondent intercepts and examines said at least one PPP negotiation packet before said at least one PPP negotiation packet reaches a PPP layer of the responding correspondent and modifies said acceptable TCP/IP header compression option type to an unacceptable TCP/IP header compression option type and transmits same to said PPP layer of the responding correspondent. The responding correspondent rejects said unacceptable TCP/IP header compression option type. Said software module receiving said modified PPP negotiation packet modifies same to said acceptable TCP/IP header compression option type, and transmitting said PPP negotiation packet to said initiating correspondent. | 12-18-2014 |
Sean M. Mercer, Halifax CA
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20130105377 | Water with Switchable Ionic Strength | 05-02-2013 |
20140076810 | Systems and Methods for Use of Water with Switchable Ionic Strength - Methods and systems for use of switchable water, which is capable of reversibly switching between an initial ionic strength and an increased ionic strength, is described. The disclosed methods and systems can be used, for example, in distillation-free removal of water from solvents, solutes, or solutions, desalination, clay settling, viscosity switching, etc. Switching from lower to higher ionic strength is readily achieved using low energy methods such as bubbling with C0 | 03-20-2014 |
Shane Andrew Mercer, Wellington NZ
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20120089571 | COMPUTER PROCESS MANAGEMENT - A computer implemented process is defined to operate on three types of objects: Task Objects, Resume Objects, and State Objects. To define a Task Objects are implemented to perform the actions required to complete a particular aspect of the process. A State Object maintains information about the currently executing process, such as the values of variables and the current location in the executing process. A Resume Object directs process execution by specifying which Task Objects or Resume Objects to execute next. A key aspect of the system is the ability to suspend execution at any time and seamlessly resume execution at either the exact point execution was stopped or at any execution point prior to suspension. This accomplished by periodically storing Snapshots of the execution to persistent storage, which can later be used to restore the state of the system to that of the Snapshot. | 04-12-2012 |
20120089989 | SYSTEMS AND METHODS FOR EXECUTING AND IMPLEMENTING COMPUTER PROCESSES IN PROCESS ENVIRONMENTS - In at least one embodiment a computer implemented method is disclosed. A computer process is extracted from a first environment including a unique process parameter and a first non-unique process parameter. The computer process is configured to execute a primary domain operation. The computer process is configured to execute the primary domain operation in a second environment comprising the unique process parameter and a second non-unique process parameter. The unique process parameter is input to the computer process and the primary domain operation is executed with the computer process in the second environment in response to inputting the unique process parameter to the computer process. | 04-12-2012 |
20120203744 | MAINTAINING DATA INTEGRITY ACROSS EXECUTION ENVIRONMENTS - Current computing solutions often involve the sharing of data across multiple computer implemented processes. To ensure data integrity throughout the execution environment, an executing process can make a request for data from a Data Provider. In response to the request, the Data Provider can bundle the data and one or more Validation Objects in a Data Object. The Data Object can be passed between executing processes, and at any point in the execution, an executing process can verify the integrity of the data by making a request to the Data Object. To facilitate the passing of Data Objects throughout a heterogeneous execution environment, a Data Object can create a representation of itself specific to the target system. The Data Objects are advantageous in that all of the necessary validation checks are centralized, thus decreasing maintenance costs and the possibility of error. | 08-09-2012 |
20130055274 | PROCESS EXECUTION COMPONENTS - Automating processes in an automation platform. Specifying a program that when executed by the platform implements the process. The program including process description, process components. The description including component initialization instructions having input parameter(s) and initialized component execution instructions having an execution state. Components having an initialization interface, an execution interface, and at least one of simulation instructions and operation instructions. Components characterized by output parameters, and operative upon receiving input parameters via the initialization interface to initialize the component. Initialized components operative upon receiving an execution state via the execution interface to execute the initialized component in accordance with the execution state, and in absence of operation instructions, to return a simulated output in the format of the output parameters in accordance with the simulation instructions. Executing the instructions by initializing each component in accordance with the component initialization instructions, executing each initialized component in accordance with the instructions. | 02-28-2013 |
20130097096 | PROCESS ENTITY GRAPHS - Implementing a process in an automation platform. Representing conceptual entities of the process as a nodes in a conceptual graph. Representing process relationships between the conceptual entities as edges between the nodes of the conceptual graph. Transforming the conceptual graph into a structural graph representing an automation design of the process. Transforming the structural graph into implementation artifacts executable on the automation platform. Entities can represent a feature, a constraint, a project phase, a screen, a data item, and a process description. Relationships can include a dependency relationship, a temporal relation-ship, and a parent-child relationship. The transformation into a structural graph being traceable between elements of the conceptual graph and the structural graph. The transformation into a structural graph controlled by a first configuration information. The transformation into a implementation artifacts controlled by a second configuration information. | 04-18-2013 |
Steven James Mercer, Guelph CA
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20130041601 | LEAK DETECTOR - A leak detector includes a sensor assembly including at least one sensor configured to sense acoustic signals; and at least one printed circuit board coupled to the sensor assembly and configured to support a processing device, the processing device comprising at least a microcontroller unit (MCU) and a digital signal processor (DSP), wherein the MCU is configured to continually receive acoustic signals from the sensor assembly, and wherein the DSP is configured to remain in a sleep mode except when the MCU wakes the DSP from the sleep mode at predetermined times. | 02-14-2013 |
20130049968 | FIRE HYDRANT LEAK DETECTOR - A leak detection system includes a housing for installation within a hydrant; at least one leak detection sensor within the housing; and a transmitter circuit in communication with the at least one leak detection sensor for communicating leak detection data. | 02-28-2013 |