Kadoch
Cigall Kadoch, Stanford, CA US
Patent application number | Description | Published |
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20140288162 | METHODS, COMPOSITIONS AND SCREENS FOR THERAPEUTICS FOR THE TREATMENT OF SYNOVIAL SARCOMA - Methods and compositions are provided for treating human synovial sarcoma (SS). Also provided are screens to identify therapeutics for the treatment of synovial sarcoma. These methods, compositions, and screens are based on the discovery that promoting the assembly of wild type BAF (also called mSWI/SNF) complexes in SS cells by increasing levels of wild type SS18 and/or decreasing levels of SS18-SSX fusion protein leads to the cessation of proliferation of malignant cells in synovial sarcoma. | 09-25-2014 |
Cigall Kadoch, Tiburon, CA US
Patent application number | Description | Published |
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20150185221 | METHODS FOR IDENTIFYING AND TREATING CANCER PATIENTS - Methods for identifying and treating cancer patients likely to respond to topoisomerase inhibitors or likely to fail to respond to topoisomerase inhibitors are provided. The methods take advantage of the newly discovered role of BAF complexes in decatenation of DNA by topoisomerase IIa. Cancer cells are frequently at least partly defective in BAF complex activity. Such cells are targeted for therapy using certain topoisomerase IIa inhibitors according to the disclosed methods of treatment. Therapy of such cells using other topoisomerase inhibitors should be avoided. | 07-02-2015 |
Daniel Kadoch, La Varenne FR
Patent application number | Description | Published |
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20100265319 | METHOD OF DISPLAYING AN IMAGE IN THREE DIMENSIONS AND PANEL THUS PRODUCED - The invention seeks to make it possible to display an image in three dimensions without additional display means, and to furnish a device that is easy to implement and applicable to drawings and paintings. To that end, a purpose of the invention is a direct display panel of images in three dimensions that comprises a bottom panel ( | 10-21-2010 |