Natarajan
Natarajan Arulsudar, Baroda IN
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20100297244 | NANODISPERSION - The present invention provides a nanodispersion comprising nanoparticles having a mean size less than 300 nm dispersed in a vehicle comprising a water miscible solvent and water, said nanoparticles comprising one or more taxane derivative, a polymer and a surfactant comprising a mixture of fatty acids or its salts and sterol or its derivatives or its salts. | 11-25-2010 |
20140030352 | NANODISPERSION - The present invention provides a nanodispersion comprising nanoparticles having a mean size less than 300 nm dispersed in a vehicle comprising a water miscible solvent and water, said nanoparticles comprising one or more taxane derivative, a polymer and a surfactant comprising a mixture of fatty acids or its salts and sterol or its derivatives or its salts. | 01-30-2014 |
Natarajan Balachander, San Jose, CA US
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20130216696 | CONTROLLED, SUSTAINED RELEASE PARTICLES FOR TREATING SEEDS AND PLANTS AND METHODS FOR MAKING THE PARTICLES - The invention relates to active particles, including core-shell particles, having low burst, controllable, sustained release which are useful for coating seeds. The active particles can also be used in sprayable and dry formulations for treating soil or plants. The particulate coating can also contain inert organic or inorganic material. The invention also relates to methods for preparing the active particles. The methods include: adding additional material to core particles to form a shell, removing active ingredient from a core surface to create an active-depleted shell, and crosslinking the outer layers of a core to form a shell. | 08-22-2013 |
Natarajan Balachander, West Lafayette, IN US
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20100004124 | Systems and methods for delivery of materials for agriculture and aquaculture - Systems and methods for delivering agricultural (including aquacultural) materials. Crystalline polymeric systems, referred to as CYC carriers, are associated with the agricultural materials, through chemical bonding or through physical association. The crystallinity of the CYC carriers results from the presence of crystallizable side chains, for example long chain n-alkyl moieties, which results in relatively low and sharp melting temperatures. One class of CYC carriers, referred to as CYSC polymers, have a majority of the crystallizable side chains pendant from the polymer backbone. Another class of CYC carriers, referred to as ECC polymers, have a majority of the crystallizable side chains attached to terminal units of the polymer backbone. The ECC polymers can for example be obtained by modification of PLGA polymers. The CYC carriers in another class are non-polymeric. Some CYC carriers, referred to as CYC assemblies, have enhanced crystallinity as a result of the physical association of crystallizable moieties which are present in different types of molecule, for example between a polymer containing crystallizable moieties and a monomer containing crystallizable moieties. Preferably the CYC carrier is bioerodable. | 01-07-2010 |
20110009571 | SYSTEMS AND METHODS FOR DELIVERY OF MATERIALS - Systems and methods for delivering release materials, for example drugs and other bioactive materials. Crystalline polymeric systems, referred to as CYC carriers, are associated with the release materials, through chemical bonding or through physical association. The crystallinity of the CYC carriers results from the presence of crystallizable side chains, for example long chain n-alkyl moieties, which results in relatively low and sharp melting temperatures. One class of CYC carriers, referred to as CYSC polymers, have a majority of the crystallizable side chains pendant from the polymer backbone. Another class of CYC carriers referred to as ECC polymers, have a majority of the crystallizable side chains attached to terminal units of the polymer backbone. The ECC polymers can for example be obtained by modification of PLGA polymers. The CYC carriers in another class of non-polymeric. Some CYC carriers, referred to as CYC assemblies, have enhanced crystallinity as a result of the physical association of crystallizable moieties which are present in different types of molecule, for example between a polymer containing crystallizable moieties and a monomer containing crystallizable moieties. For some uses, particularly the delivery of drugs, a bioerodable CYC carrier is preferably used. | 01-13-2011 |
20130243839 | Controlled, Sustained Release Particles for Treating Seeds and Plants and Methods for Making the Particles - The invention relates to active particles, including core-shell particles, having low burst, controllable, sustained release which are useful for coating seeds. The active particles can also be used in sprayable and dry formulations for treating soil or plants. The particulate coating can also contain inert organic or inorganic material. The invention also relates to methods for preparing the active particles. The methods include: adding additional material to core particles to form a shell, removing active ingredient from a core surface to create an active-depleted shell, and crosslinking the outer layers of a core to form a shell. | 09-19-2013 |
Natarajan Balanchander, Menlo Park, CA US
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20120082709 | COMPOSITIONS AND METHODS FOR DELIVERY OF MATERIALS - Compositions for delivering release materials, for example drugs, agricultural materials, other bioactive materials, cosmetic materials, organic or inorganic compounds which take part in or catalyse a chemical reaction, a fragrance-emitting material for a vaporizer, or a lubricating material. The release material is associated with a crystalline carrier. The carrier may be a crystalline polymer containing a plurality of crystalline groups or a crystalline monomer which contains a single crystalline group, the crystalline group preferably comprising a straight chain polymethylene radical containing at least 16 carbon atoms. Some of the carriers are obtained by modifying hyaluronic acid, collagen, gelatin, a polysaccharide, a carbohydrate or cyclodextran. The release material may contain a similar crystalline group, for example may be an active compound which has been modified to introduce a crystalline group. | 04-05-2012 |
Natarajan Balanchander, West Lafayette, IN US
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20120088659 | Compositions and Methods for Delivery of Materials - Compositions for the controlled delivery of active ingredients, for example, drugs, cosmetic materials, and agricultural materials. The compositions include a multiplicity of particles, each of the particles comprising (1) a microstructure comprising a semicrystalline polymer which has a peak melting temperature, Tp, of at least 20° C., and (2) the active ingredient. The microstructure comprises | 04-12-2012 |
Natarajan Kumaravelu, Chennai IN
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20150269575 | SYSTEM AND METHOD FOR SECURE PAYMENT TRANSACTIONS DURING A CHAT SESSION - A method for secure payment transactions over a network between a support help desk computing system and a customer computing system is provided. The method includes establishing a chat session between the help desk and the customer using a chat application program; receiving a purchase order from the customer; communicating a unique URL payment link to the customer, wherein the URL payment link is configured for allowing the customer to establish communication with an order processing system to provide sensitive payment information to the order processing system; receiving the sensitive payment information at the order processing system communicated from the customer; encrypting the sensitive payment information; providing the encrypted sensitive payment information to the help desk, wherein the encrypted sensitive payment information is displayed in a masked format on a display of the help desk; and completing the purchase order using the encrypted sensitive payment information. | 09-24-2015 |
Natarajan Manthiramoorthy, Fremont, CA US
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20140105037 | Determining Transmission Parameters for Transmitting Beacon Framers - A method includes dynamically determining transmission parameters for transmission of beacon frames corresponding to a Wireless Local Area Network (WLAN) supported by an access point. The transmission parameters being based on zero or more client devices connected to the WLAN or monitored data indicative of a load at the access point. | 04-17-2014 |
20140369248 | DETERMINING TRANSMISSION PARAMETERS FOR TRANSMITTING BEACON FRAMES - A method includes dynamically determining transmission parameters for transmission of beacon frames corresponding to a Wireless Local Area Network (WLAN) supported by an access point. The transmission parameters being based on zero or more client devices connected to the WLAN or monitored data indicative of a load at the access point. | 12-18-2014 |
20140376537 | DETERMINING TRANSMISSION PARAMETERS FOR TRANSMITTING BEACON FRAMES - A method includes dynamically determining transmission parameters for transmission of beacon frames corresponding to a Wireless Local Area Network (WLAN) supported by an access point. The transmission parameters being based on zero or more client devices connected to the WLAN or monitored data indicative of a load at the access point. | 12-25-2014 |
Natarajan Mathivanan, Coimbatore IN
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20130143912 | SUBLINGUAL ZOLPIDEM FORMULATIONS - The present disclosure provides pharmaceutical compositions for the delivery of a hypnotic agent across the oral mucosa. In particular, the compositions devoid of buffer and in the presence of alkaline oxides capable of raising the pH of saliva to a pH greater than about 7.0 thereby facilitate the substantially complete conversion of the hypnotic agent from its ionized to its un-ionized form. As a result, the dose of hypnotic agent is rapidly and efficiently absorbed by the oral mucosa with surprisingly low inter-subject variability. Furthermore, delivery of the hypnotic agent across the oral mucosa advantageously bypasses hepatic first pass metabolism of the drug and avoids enzymatic degradation of the drug within the gastrointestinal tract. Methods for using the compositions of the present invention for treating sleep disorders such as insomnia are also provided. | 06-06-2013 |
Natarajan Ramanchandran, Uniontown, OH US
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20160065002 | CONTROLLING POWER PROVIDED TO AN AUTOMATED BANKING SYSTEM - In an example embodiment, an automated banking machine causes financial transfers related to financial accounts that correspond to data read from user cards. The automated banking machine also includes devices that control the supply of power to included devices to facilitate the completing a transaction when a decline or loss of power is encountered. | 03-03-2016 |
Natarajan Ramasubramanyan, Abbott Park, IL US
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20120123688 | RAMAN SPECTROSCOPY FOR BIOPROCESS OPERATIONS - A method of characterizing a multi-component mixture for use in a bioprocess operation that includes providing a multi-component mixture standard with pre-determined amounts of known components; performing a Raman Spectroscopy analysis on the multi-component mixture standard; providing a multi-component test mixture from the bioprocess operation; performing a Raman Spectroscopy analysis on the multi-component test mixture; and comparing the analysis of the multi-component mixture standard and the multi-component test mixture to characterize the multi-component test mixture. In one embodiment, the multi-component mixture standard and the multi-component test mixture both comprise one or more of, at least two, at least three of, or each of, a polysaccharide (e.g. sucrose or mannitol), an amino acid (e.g., L-arginine, L-histidine or L-ornithine), a surfactant (e.g. polysorbate 80) and a pH buffer (e.g., a citrate formulation). | 05-17-2012 |
20120129196 | HIGHLY SENSITIVE MONOCLONAL ANTIBODY RESIDUAL DETECTION ASSAY - The present invention relates to compositions and highly sensitive methods for the detection of biotechnology product residual when monitoring product carry over and/or for cleaning verification in the manufacture of biotechnology products. In particular, the present invention is directed to immunoassays wherein one or more capture antibodies, or antigen binding fragments thereof, are used to detect residuals associated with the production of biotechnology products. | 05-24-2012 |
Natarajan Ramasubramanyan, Westborough, MA US
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20120238730 | INTEGRATED APPROACH TO THE ISOLATION AND PURIFICATION OF ANTIBODIES - Disclosed herein is an integrated approach to purification process development and execution, including processes comprising particular capture and fine purification steps; processes that employ of a minimal number of buffer systems, and processes that make use of minimally-corrosive buffer systems, as well as combinations thereof. | 09-20-2012 |
20130338344 | PROTEIN PURIFICATION METHODS TO REDUCE ACIDIC SPECIES - The instant invention relates to the field of protein production and purification, and in particular to compositions and processes for controlling the amount of charge variants, aggregates, and fragments of a protein of interest, as well as host cell proteins, present in purified preparations by applying particular chromatography conditions during such protein purification. | 12-19-2013 |
20140072585 | NOVEL PURIFICATION OF ANTIBODIES USING HYDROPHOBIC INTERACTION CHROMATOGRAPHY - Disclosed herein are compositions and methods for purifying antibody products from a sample matrix. In particular, the present invention relates to compositions and methods for purifying antibody products employing hydrophobic interaction chromatography media. In certain embodiments, the invention provides a method for reducing process-related impurities (e.g., host cell proteins), as well as product-related substances, including molecular weight variants (e.g., aggregates and fragments of the antibody product). | 03-13-2014 |
20150110799 | LOW ACIDIC SPECIES COMPOSITIONS AND METHODS FOR PRODUCING AND USING THE SAME - The instant invention relates to low acidic species (AR) compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods, e.g., cell culture and/or protein purification methods, for producing such low AR compositions. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNFα is detrimental, are also provided. | 04-23-2015 |
20150132801 | LOW ACIDIC SPECIES COMPOSITIONS AND METHODS FOR PRODUCING AND USING THE SAME - The instant invention relates to low acidic species (AR) compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods, e.g., cell culture and/or protein purification methods, for producing such low AR compositions. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNFα is detrimental, are also provided. | 05-14-2015 |
20150140006 | LOW ACIDIC SPECIES COMPOSITIONS AND METHODS FOR PRODUCING AND USING THE SAME - The instant invention relates to low acidic species (AR) compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods, e.g., cell culture and/or protein purification methods, for producing such low AR compositions. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNFα is detrimental, are also provided. | 05-21-2015 |
20150141623 | PROTEIN PURIFICATION METHODS TO REDUCE ACIDIC SPECIES - The instant invention relates to the field of protein production and purification, and in particular to compositions and processes for controlling the amount of charge variants, aggregates, and fragments of a protein of interest, as well as host cell proteins, present in purified preparations by applying particular chromatography conditions during such protein purification. | 05-21-2015 |
20150259410 | LOW ACIDIC SPECIES COMPOSITIONS AND METHODS FOR PRODUCING AND USING THE SAME - The instant invention relates to low acidic species (AR) compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods, e.g., cell culture and/or protein purification methods, for producing such low AR compositions. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNFα is detrimental, are also provided. | 09-17-2015 |
20150299249 | PURIFICATION OF PROTEINS USING HYDROPHOBIC INTERACTION CHROMATOGRAPHY - The present invention is directed to methods for purifying a protein of interest, e.g., an antibody, from a sample comprising the protein of interest and at least one impurity, e.g., an aggregate, by employing a hydrophobic interaction chromatography (HIC) method that allows for binding of both the protein of interest and the at least one impurity under strong binding conditions. The present invention is based, at least in part, on the finding that both flow through and bind-elute techniques can be combined to achieve greater purification and recovery of a protein of interest, e.g., an antibody, under isocratic wash conditions and strong binding conditions. | 10-22-2015 |
Natarajan Sambamoorthy, Union City, CA US
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20120066295 | SYSTEM AND METHOD FOR ACCESSING AND UTILIZING A PLURALITY OF SMARTPHONE APPLICATIONS - The present invention is a system to access and utilize a plurality of smartphone applications that includes a server system, one or more smartphones and a communications network where the server system is in communication with the smartphones over the communications network. The system smartphone applications include an autograph smartphone application, a memory puzzle smartphone application and a daily journal application, all of which have a plurality of application updates that are provided to the smartphone applications. | 03-15-2012 |
Natarajan Setheraman, Hanover, NH US
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20140200180 | METHOD FOR PRODUCING PROTEINS IN PICHIA PASTORIS THAT LACK DETECTABLE CROSS BINDING ACTIVITY TO ANTIBODIES AGAINST HOST CELL ANTIGENS - Methods for producing proteins and glycoproteins in | 07-17-2014 |
Natarajan Valdhyanathan, Greensboro, NC US
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20090080461 | FRAME ALTERATION LOGIC FOR NETWORK PROCESSORS - Packet switching node in a communication system includes apparatus for receiving incoming information packets or frames which contain header portions with formatting control blocks. Information in the frame's header contains frame alteration commands for modifying the information in the frame. The modifications include adding new information, deleting information, and overlaying information. Decoders and control devices in an alteration engine interpret the commands and apply the modifications to the frame data. Common and standard data patterns are stored for insertion or overlaying to conserve data packet space. | 03-26-2009 |
Natarajan Vankatakrishnan, Louisville, KY US
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20100070091 | ENERGY MANAGEMENT OF HOUSEHOLD APPLIANCES - An appliance for conditioning air of a room comprises one or more power consuming features/functions including a temperature controlling element for one of heating and cooling air. A controller is operatively connected to the one or more power consuming features/functions. The controller is configured to receive and process a signal indicative of a utility state. The controller operates the appliance in one of a plurality of operating modes, including at least a normal operating mode and an energy savings mode in response to the received signal. The controller is configured to at least one of selectively adjust and deactivate at least one of the one or more power consuming features/functions to reduce power consumption of the appliance in the energy savings mode. | 03-18-2010 |
20100090806 | MANAGEMENT CONTROL OF HOUSEHOLD APPLIANCES USING RFID COMMUNICATION - A method and system for communicating with an associated home appliance having a micro-controller includes providing a master device that emits a signal in response to data indicative of energy operational costs. One or more RFID tags receive the master device signal. The RFID tag(s) are connected to the associated home appliance micro-controller to control the operational mode of the home appliance. Preferably, four RFID tags are responsive to four distinct frequency signal emitted by the master device and are representative of different modes of operation for the associated home appliance. | 04-15-2010 |
Natarajan Venkatachalem, Erode IN
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20150206022 | SYSTEM AND METHOD FOR CLASSIFYING A SKIN INFECTION - A system and computer-implemented method for classifying skin disorders using an image of a skin portion is provided. The system comprises a server configured to receive the image of the skin portion from an electronic communication device and process the received image of the skin portion, wherein the processing comprises at least one of: resizing, removing artifacts and noise, applying new color space, sharpening the image and correcting background. Furthermore, the server is configured to segment the processed image to identify the region of interest within the processed image and extract one or more features from the identified region of interest. The system further comprises a trained learning module configured to classify the skin disorder by mapping the extracted features with pre-stored images, wherein the pre-stored images that map with the extracted features are associated with a particular category of skin disorder. | 07-23-2015 |
Natarajan Vijayarangan, Siruseri IN
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20150180737 | SYSTEM AND METHOD FOR DETERMINING NUMBER OF COMPUTING RESOURCES FOR EXECUTING A PLURALITY OF JOBS - Method and system for determining the number of computing resources for executing a plurality of jobs. In accordance with the method and the system, the plurality of jobs along with a plurality of variables associated to the plurality of jobs may be received. The plurality of variables may include a mean processing time (μ), a standard deviation (σ), a service level agreement (α), and a confidence level (1-α). After the receipt of the plurality of variables, an inverse parameter (γ) may be determined using the mean processing time (μ), the standard deviation (σ), and the confidence level (1-α). Further, a queue length (k) may be computed based upon the total processing time (T), the mean processing time (μ), the standard deviation (σ), and the inverse parameter (γ). Finally, the queue length (k) and the number of jobs (n) may be processed in order to determine the number of computing resources. | 06-25-2015 |
20150229542 | SYSTEM AND METHOD FOR DETERMINING TOTAL PROCESSING TIME FOR EXECUTING A PLURALITY OF JOBS - Method and system for determining the total processing time required for executing a plurality of jobs. In certain aspects, a set of jobs along with a mean processing time and a queue length are received. The set of jobs are distributed across computing resources based upon the queue length. A set of priority jobs is received when the execution of a subset of jobs from the set of jobs has been executed in a first processing time (T | 08-13-2015 |
20150248313 | SYSTEM AND METHOD FOR DETERMINING TOTAL PROCESSING TIME FOR EXECUTING A PLURALITY OF JOBS - Method and system for determining the total processing time required for executing a plurality of jobs (n). The plurality of jobs along with a mean processing time (μ), and a queue length (k) are received. A number of preliminary jobs (p) of the plurality of jobs (n) are distributed across computing resources based upon the queue length (k). A first processing time (T | 09-03-2015 |
Natarajan Vijayarangan, Chennai IN
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20160078217 | Computer Implemented Systems and Methods for Generating and Recovering an Authorization Code - A computer implemented system and method for generating and recovering an authorization code. The system creates an authorization code by accepting a base-sentence from a user. Based on the characters present in this base-sentence, the system computes a base-sentence matrix. The system also generates a plurality of patterns. The user can either select the pattern from the multiple patterns suggested by the system or can create his/her own pattern. The system then performs multiplications between the base-sentence matrix and the selected pattern matrix at different stages in the path forward, for obtaining a strong authorization code. In case the user forgets the base sentence, the system also has provisions to manage forgotten authorization code. This is done by fragmenting the base-sentence into different matrices and storing the fragmented matrices into a repository after computing matrix multiplication with a security question answer and with a secret key provided by the user. | 03-17-2016 |
Natarajan Vijayarangan, Hyderabad IN
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20090103717 | System and method for implementing elliptic curve scalar multiplication in cryptography - A system and method for implementing the Elliptic Curve scalar multiplication method in cryptography, where the Double Base Number System is expressed in decreasing order of exponents and further on using it to determine Elliptic curve scalar multiplication over a finite elliptic curve. | 04-23-2009 |
20090193065 | Deterministic random number generator for cryptography and digital watermarking - A deterministic random number generator comprising: | 07-30-2009 |
Natarajan Vijayarangan, Andhra Pradesh IN
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20090262925 | Method for designing a secure hash function and a system thereof - A system and method for designing a secure hash function is provided. Both of which have been designed for secure hash functionality, Secure Hash Algorithm (SHA-3) using pre processing (MP) methods and to help reduce hash collisions. It is a one way hash function which is a combination of message pre-processing which is a bijective function and the cipher block chaining mode (CBC). | 10-22-2009 |
Natarajan Vijayasankaran, South San Francisco, CA US
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20130281355 | CELL CULTURE COMPOSITIONS AND METHODS FOR POLYPEPTIDE PRODUCTION - Cell culture media, such as chemically defined cell culture media, are provided, as are methods of using the media for cell growth (i.e., cell culture) and polypeptide (e.g., antibody) production. Compositions comprising polypeptides produced by the methods are also provided. | 10-24-2013 |
20140308273 | CELL CULTURE MEDIA AND METHODS OF ANTIBODY PRODUCTION - Cell culture media are provided herein as are methods of using the media for cell culture and antibody production from cells. Compositions comprising antibodies and fragments thereof, produced by the methods herein are also provided. | 10-16-2014 |
20140314779 | CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION - Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides, such as therapeutic polypeptides, produced by the methods herein are also provided. | 10-23-2014 |
20150267237 | CELL CULTURE COMPOSITIONS AND METHODS FOR POLYPEPTIDE PRODUCTION - Cell culture media, such as chemically defined cell culture media, are provided, as are methods of using the media for cell growth (i.e., cell culture) and polypeptide (e.g., antibody) production. Compositions comprising polypeptides produced by the methods are also provided. | 09-24-2015 |
20160002593 | CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION - Cell culture media comprising antioxidants are provided herein as are methods of using the media for cell culturing and polypeptide production from cells. Compositions comprising polypeptides, such as therapeutic polypeptides, produced by the methods herein are also provided. | 01-07-2016 |
20160102141 | CELL CULTURE MEDIA AND METHODS OF ANTIBODY PRODUCTION - Cell culture media are provided herein as are methods of using the media for cell culture and antibody production from cells. Compositions comprising antibodies and fragments thereof, produced by the methods herein are also provided. | 04-14-2016 |
Natarajan Vijayrangan, Andhra Pradesh IN
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20090085780 | Method for preventing and detecting hash collisions of data during the data transmission - A means for avoiding hash collisions by means of message pre-processing function to increase randomness and reduce redundancy of an input message whereby hash collisions are avoided when it is applied before hashing any message and the message pre-processing function comprises 4 steps like shuffling of bits, compression T-function and LFSR which steps increase the entropy of the input message at the end of 4 rounds, the output becomes more random. | 04-02-2009 |
Natarajan Vishvanathan, Austin, TX US
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20100262944 | OBJECT PLACEMENT IN INTEGRATED CIRCUIT DESIGN - A method, system, and computer usable program product for an improved object placement in integrated circuit design are provided in the illustrative embodiments. The IC design includes cells, the cells including electronic components, wires, and pins defined for interconnections of the IC. An initial placement corresponding to the design is received. A characteristic of the initial placement is estimated, which may include congestion, pin density, or both in an area of the initial placement. A transformation is performed on a part of the initial placement including the area to improve the characteristic. If the characteristic has improved in the transformed placement, a final placement corresponding to the transformed placement is produced. The transformation may be any combination of resizing an object, weighting a connection, clustering a plurality of objects, shortening of a route taken by a wire, and straightening a bend in a wire in the initial placement. | 10-14-2010 |