Patent application number | Description | Published |
20100206425 | FILLING SYSTEM FOR POTENTIALLY HAZARDOUS MATERIALS - Systems, devices, and methods for filling containers with radioactive materials are described. In certain embodiments, the systems comprise a shielding material that substantially defines a chamber and, preferably, substantially blocks radioactivity, a conduit extending through the shielding material into the chamber, and a securing unit that is disposed in the chamber proximal to the conduit and is adapted to receive a container through the conduit. | 08-19-2010 |
20100224791 | SYSTEMS AND METHODS FOR RADIOISOTOPE GENERATION - Systems and methods are disclosed for producing customized, predictable and reproducible supplies of radioisotopes using, for example, a reactor housing that is fabricated from a radioactive shielding material and has both an internal volume and a surface that comprises an entry port and an exit port, a chromatographic column that is positioned within said internal volume such that a first end of said column is in fluid communication with said entry port and a second end of said column is in fluid communication with said exit port, and a changeable filter module that is disposed external to said reactor housing and in fluid communication with said exit port. | 09-09-2010 |
Patent application number | Description | Published |
20090060947 | Immunological compositions - The disclosure relates to immunological compositions for vaccinating human beings against infection by the Human Immunodeficiency Virus (HIV). | 03-05-2009 |
20090142373 | Immunizing Against HIV Infection - A virus neutralizing level of antibodies to a primary HIV isolate is generated in a host by a prime-boost administration of antigents. The primary antigen is a DNA molecule encoding an envelop glycoprotein of a primary isolate of HIV-1 while the boosting antigen is either a non-infectious, non-replicating HIV-like particle having the envelope glycoprotein of a primary isolate of HIV-1 or an attenuated viral vector expressing an envelope glycoprotein of a primary isolate of HIV-1. | 06-04-2009 |
20090156519 | Modified KSA and Uses Thereof - The present invention relates to a nucleic acid encoding a polypeptide and the use of the nucleic acid or polypeptide in preventing and/or treating cancer. In particular, the invention relates to improved vectors for the insertion and expression of foreign genes encoding tumor antigens for use in immunotherapeutic treatment of cancer. | 06-18-2009 |
20100291037 | IMMUNOGENICITY USING A COMBINATION OF DNA AND VACCINIA VIRUS VECTOR VACCINES - This invention relates to improved methods of inducing an immune response for the prevention or treatment of HIV-1 infection by using a nucleic acid vaccine in conjunction with a recombinant viral vaccine, e.g., a poxvirus vaccine, to potentiate and broaden the immune response. The present invention further provides a particularly effective vaccine regimen comprising a DNA vaccine used in combination with a poxvirus virus, especially NYVAC or ALVAC. | 11-18-2010 |
20110250234 | Immunogenic Polypeptides Encoded by MAGE Minigenes and Uses Thereof - The invention discloses immunogenic polypeptides comprising several MAGE-specific antigen epitopes selected from different (i.e. discrete) members of the MAGE protein family, nucleic acids coding therefor, recombinant viruses and/or cells comprising said nucleic acids, and compositions thereof. Methods for eliciting or inducing MAGE-specific immune responses utilizing the aforementioned immunogenic agents are also disclosed. | 10-13-2011 |
Patent application number | Description | Published |
20080234345 | METHOD FOR REDUCING OR ALLEVIATING INFLAMMATION IN THE DIGESTIVE TRACT - A method is provided for reducing or alleviating inflammation or a pathological process associated therewith or secondary thereto in a subject having an inflammatory disease of the digestive tract. The method comprises administering to the subject an anti-inflammatorily effective amount of an ACE2 inhibitor. | 09-25-2008 |
20090186014 | METHOD FOR TREATMENT OF PANCREATITIS - A method for treating acute or chronic pancreatitis in a subject comprises administering to the subject a therapeutically effective amount of an ACE2 inhibitor. | 07-23-2009 |
20120009183 | METHOD FOR TREATMENT OF PANCREATITIS - A method for treating acute or chronic pancreatitis in a subject comprises administering to the subject a therapeutically effective amount of an ACE2 inhibitor. | 01-12-2012 |
20130195762 | FAT CELLS AND METHODS OF USING THEREOF - Beige cells that contain a reporter gene are disclosed herein. Such cells can be used to identify therapeutic agents for treatment of obesity and its associated disorders, such as diabetes. | 08-01-2013 |
20150232881 | CRISPR-RELATED METHODS AND COMPOSITIONS WITH GOVERNING gRNAS - Disclosed herein are methods and compositions useful in targeting a payload to, or editing a target nucleic acid, where a governing gRNA molecule is used to target, optionally inactivate, a Cas9 molecule or a Cas9 molecule/gRNA complex. | 08-20-2015 |
Patent application number | Description | Published |
20100009361 | COMPOSITIONS AND METHODS FOR DETECTING NOONAN SYNDROME - Diagnostic and therapeutic applications for Noonan Syndrome are described. The diagnostic and therapeutic applications are based on certain mutations in a RAS-specific guanine nucleotide exchange factor gene SOS1 or its expression product. The diagnostic and therapeutic applications are also based on certain mutations in a serine/threonine protein kinase gene RAF1 or its expression product thereof. Also described are nucleotide sequences, amino acid sequences, probes, and primers related to RAF1 or SOS1, and variants thereof, as well as host cells expressing such variants. | 01-14-2010 |
20110059851 | SHOC2 Mutations Causing Noonan-Like Syndrome With Loose Anagen Hair - The present invention is directed to methods of diagnosing Noonan-like syndrome with loose anagen hair comprising detecting a mutation in SHOC2 gene. One specific diagnostic mutation disclosed is an A-to-G transition at position 4 resulting in a mutation at position 2 of SHOC2 amino acid sequence from serine to glycine. The invention also provides related sequences and kits. | 03-10-2011 |
20130029332 | COMPOSITIONS AND METHODS FOR DETECTING NOONAN SYNDROME - Diagnostic and therapeutic applications for Noonan Syndrome are described. The diagnostic and therapeutic applications are based on certain mutations in a RAS-specific guanine nucleotide exchange factor gene SOS1 or its expression product. The diagnostic and therapeutic applications are also based on certain mutations in a serine/threonine protein kinase gen RAF1 or its expression product thereof. Also described are nucleotide sequences, amino acid sequences, probes, and primers related to RAF1 or SOS1, and variants thereof, as well as host cells expressing such variants. | 01-31-2013 |
20150017649 | COMPOSITIONS AND METHODS FOR DETECTING NOONAN SYNDROME - Diagnostic and therapeutic applications for Noonan Syndrome are described. The diagnostic and therapeutic applications are based on certain mutations in a RAS-specific guanine nucleotide exchange factor gene SOS1 or its expression product. The diagnostic and therapeutic applications are also based on certain mutations in a serine/threonine protein kinase gene RAFl or its expression product thereof. Also described are nucleotide sequences, amino acid sequences, probes, and primers related to RAF1 or SOS1, and variants thereof, as well as host cells expressing such variants. | 01-15-2015 |
Patent application number | Description | Published |
20110293980 | BATTERY CUSHION AND INSULATOR - An application for a battery shield including a set of walls made of a resilient, elastomeric material and a base made of the same resilient, elastomeric material. A bottom edge of the walls connects to an edge of the base forming a rectangular cavity having a width and a depth. The width is substantially equivalent to the width of a battery pack and the depth is substantially equivalent to the depth of the battery pack, thereby the battery shield snuggly fits around the battery pack, reducing shock and vibration of the battery pack from external shock and vibration and insulating the battery pack from ambient temperature extremes. | 12-01-2011 |
20110293987 | BATTERY TERMINAL CONNECTION SYSTEM - An application for a battery terminal interface includes a battery terminal interface shield made of a conductive metal having a lower impedance than an impedance of lead. The battery terminal interface shield has an inner surface and an outer surface. The inner surface contacts substantially all of an outer surface of a battery terminal and the outer surface contacts a cable connector, thereby distributing electrical current to/from the cable connector to substantially the entire outer surface of the battery terminal. Since the battery terminal is made from lead and the battery terminal interface shield is made from a better conductor, electric current is better distributed across a greater surface area of the battery terminal. | 12-01-2011 |
20110293997 | BATTERY PACK THERMAL PROTECTION FROM HEAT STERILIZATION - An application for a battery pack that includes a set of walls made of sturdy material, power interface terminals and battery cells/electronics held within the walls. The battery cells are separated from the walls by a highly insulating material, thereby reducing the temperature that the battery cells reach during heat sterilization cycles performed on the battery pack after, for example, exposure of the battery pack to pathogens. | 12-01-2011 |
20120031645 | SYSTEM, METHOD AND APPARATUS FOR CONNECTING BATTERY CELLS - An application for a battery terminal strip for connecting to a terminal of at least one battery cell describes a battery terminal strip that is a strip of metal that has at least one weld point formed in the strip of metal. Each of the weld points having a protrusion on a first surface of the strip of metal such that the protrusion contacts a terminal of a battery cell of the at least one battery cell thereby forming an air gap between the first surface of the strip of metal and the terminal of the battery cell, thereby reducing heat transfer from the strip of metal to the battery during welding. | 02-09-2012 |
20120149258 | SYSTEM, METHOD AND APPARATUS FOR CONNECTING BATTERY CELLS - A battery terminal strip for connecting to a terminal of at least one battery cell where the battery terminal strip includes four weld points formed in a strip of metal for each battery cell. Each of the weld points has a protrusion on a first surface of the strip of metal such that the protrusion contacts a terminal of the battery cell. The result is an air gap between the first surface of the strip of metal and the terminal of the battery cell. The air gap reduces heat transfer from the strip of metal to the battery during welding. A cross-cut is formed/cut in the strip of metal. Each segment of the cross-cut creates a gap in the strip of metal such that each gap is between two different weld points of the four weld points. | 06-14-2012 |
20120225331 | BATTERY PACK PROTECTION SYSTEM - An application for a battery pack that includes walls made of sturdy material, power interface terminals and battery cells/electronics held within the walls. A protective layer contains the battery cells. The protective layer reduces external harm from heat, out-gassing and/or explosion of one or more of the battery cells. | 09-06-2012 |
20120244399 | BATTERY PACK THERMAL VENT PROTECTION - A battery pack includes a set of walls made of sturdy material, power interface terminals and battery cells and optionally electronics held within the walls. A spring-loaded check valve installed in a wall of the enclosure fluidly connects an area within the enclosure with an atmosphere outside of the enclosure. The one-way check valve allows pressurized fluids to flow out of the enclosure while preventing pressurized fluids from flowing from the atmosphere into the enclosure. | 09-27-2012 |