Itaka
Keiji Itaka, Tokyo JP
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20080249049 | Polycationically Charged Polymer and the Use of the Same as a Carrier for Nucleic Acid - A composition for the delivery of nucleic acid to target cells or tissues, which comprises polycationically charged polymer as a carrier of nucleic acid is provided. Said polycationically charged polymer is a polymer which may comprise a charged polymer segment having a main chain based on poly(amino acid), polysaccharide, polyester, polyether, polyurethane or vinyl polymer and having, as a side chain, a group of formula —NH—(CH | 10-09-2008 |
20100137512 | Polyethylene glycol/polycation block copolymers - The invention provides block copolymers formed of poly(ethylene glycol) segments and poly(amino acid derivative) segments having side chains of at least one kind of specific amine residue. The invention also provides polyion complexes of such copolymers with polynucleotides and the like. These block copolymers are useful as carriers for in vivo delivery of active substances such as DNA. | 06-03-2010 |
20120177594 | POLYION COMPLEX COMPRISING PHD2 EXPRESSION INHIBITING SUBSTANCE - The present invention aims to provide a gene delivery system with higher safety and higher sustainability, which is effective for the treatment of ischemic diseases and the like, and the like. The present invention provides a pharmaceutical composition containing, as an active ingredient, a polyanionic substance that suppresses expression of PHD2, and containing a polyion complex of the polyanionic substance and a polycation chargeable polymer. | 07-12-2012 |
Keiji Itaka, Toshima-Ku JP
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20100099190 | CULTURED CELL CONSTRUCTION CONTAINING SPHEROIDS OF MESENCHYMAL STEM CELLS AND UTILIZATION THEREOF - Facing no ethical obstacle and easily to be isolated, multipotent concretely mesenchymal stem cells (MSCs) are one of the most powerful tools in reconstructive medicine. Here the inventors introduced 3D multicelluar spheroids culture construction based on photolithography and micropatterning techniques to improve multipotent differentiation efficiency of MSCs to adult cells. This invention, the 3D spheroid cultured construction for MSCs, leads to great improve of the differentiation efficiency. This invention relates to a cultured cell construct comprising a support; at least one island on the support; a hydrophilic and cytophobic substance applied on the surface of said support so as to encircle the island; and a spheroid which is derived from MSCs, said spheroid being in contact with the island. | 04-22-2010 |
Keiji Itaka, Bunkyo-Ku JP
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20130109743 | NUCLEIC ACID DELIVERY COMPOSITION AND CARRIER COMPOSITION, PHARMACEUTICAL COMPOSITION USING THE SAME, AND METHOD FOR DELIVERING NUCLEIC ACID | 05-02-2013 |
Kenji Itaka, Ibaraki JP
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20120067410 | SCHOTTKY-BARRIER JUNCTION ELEMENT, AND PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL USING THE SAME - A Schottky-barrier junction element | 03-22-2012 |
Yasuhito Itaka, Saitama-Ken JP
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20110049631 | SEMICONDUCTOR INTEGRATED CIRCUIT HAVING INSULATED GATE FIELD EFFECT TRANSISTORS - In one embodiment, a semiconductor integrated circuit is provided a first well region, a second well region, a first body bias supply unit and a second body bias supply unit. The first well region includes a first transistor having a first threshold voltage. The second well region includes a second transistor having an absolute value of a second threshold voltage higher than an absolute value of the first threshold voltage. The second well region is separated from the first well region. The second well region has the same conductive type as the first well region. The first body bias supply unit supplies a first body bias voltage to the first well region. The second body bias supply unit supplies a second body bias voltage to the second well region. | 03-03-2011 |
Yasuhito Itaka, Yokohama-Shi JP
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20090083686 | Semiconductor integrated circuit device formed by automatic layout wiring by use of standard cells and design method of fixing its well potential - Standard cells without a well potential fixing active region ( | 03-26-2009 |