Patent application number | Description | Published |
20100121434 | Medical Devices and Delivery Systems for Delivering Medical Devices - Medical devices and delivery systems for delivering medical devices to a target location within a subject. In some embodiments the medical devices can be locked in a fully deployed and locked configuration. In some embodiments the delivery systems are configured with a single actuator to control the movement of multiple components of the delivery system. In some embodiments the actuator controls the independent and dependent movement of multiple components of the delivery system. | 05-13-2010 |
20100280495 | Medical Devices and Delivery Systems for Delivering Medical Devices - Medical devices and delivery systems for delivering medical devices to a target location within a subject. In some embodiments the medical devices can be locked in a fully deployed and locked configuration. In some embodiments the delivery systems are configured with a single actuator to control the movement of multiple components of the delivery system. In some embodiments the actuator controls the independent and dependent movement of multiple components of the delivery system. | 11-04-2010 |
20110052020 | Lens Capsule Size Estimation - Methods of estimating the size of an ocular lens capsule. | 03-03-2011 |
20120022547 | Intraocular Lens Delivery Devices and Methods of Use - Intraocular lens delivery devices and methods of use. | 01-26-2012 |
20120046740 | MEDICAL DEVICES AND DELIVERY SYSTEMS FOR DELIVERING MEDICAL DEVICES - Medical devices and delivery systems for delivering medical devices to a target location within a subject. In some embodiments the medical devices can be locked in a fully deployed and locked configuration. In some embodiments the delivery systems are configured with a single actuator to control the movement of multiple components of the delivery system. In some embodiments the actuator controls the independent and dependent movement of multiple components of the delivery system. | 02-23-2012 |
20130073037 | PROSTHETIC HEART VALVE IMPLANTATION - A prosthetic heart valve includes an expandable stent and a leaflet assembly coupled to the expandable stent. The expandable stent is radially expandable from a first size for intraluminal delivery through a body passageway to a second size for implantation of the prosthetic heart valve in the body passageway. The leaflet assembly includes leaflets movable between an open position permitting flow past the expanded stent and a closed position substantially restricting flow past the expanded stent. Each of the leaflets is coaptable with each of the other leaflets in the closed position to define a coaptation region of about 15 percent to about 35 percent of the overall height of each of the plurality of leaflets. | 03-21-2013 |
20130131794 | Accommodating Intraocular Lenses and Methods of Use - Accommodating intraocular lenses and methods of use. The accommodating intraocular lenses include peripheral regions that are adapted to be more sensitive to certain types of forces than to other types of forces. | 05-23-2013 |
20130250239 | Lens Capsule Size Estimation - Methods of estimating the size of an ocular lens capsule. | 09-26-2013 |
20130302845 | MEASURING BIOLOGICAL TISSUE - A tissue measurement system includes a clamp, a measuring head, and a deflection sensor. The clamp includes a first plate and a second plate releasably engageable with one another to secure a substantially planar biological tissue. In the engaged position, the first and second plates define at least a portion of a test section along which a portion of the secured substantially planar biological tissue is disposed. The measuring head is movable toward the test section and into contact with the portion of the substantially planar biological tissue disposed along the test section. The deflection sensor is responsive to movement of the biological tissue contacted by the measuring head. | 11-14-2013 |
20140142588 | Intraocular Lens Delivery Devices and Methods of Use - Intraocular lens delivery devices and methods of use. | 05-22-2014 |
20150209142 | MEDICAL DEVICES AND DELIVERY SYSTEMS FOR DELIVERING MEDICAL DEVICES - Medical devices and delivery systems for delivering medical devices to a target location within a subject. In some embodiments the medical devices can be locked in a fully deployed and locked configuration. In some embodiments the delivery systems are configured with a single actuator to control the movement of multiple components of the delivery system. In some embodiments the actuator controls the independent and dependent movement of multiple components of the delivery system. | 07-30-2015 |
20150257874 | INTRAOCULAR LENS DELIVERY DEVICES AND METHODS OF USE - Intraocular lens delivery devices and methods of use. | 09-17-2015 |
Patent application number | Description | Published |
20100219092 | Two-Part Package for Medical Implant - The invention provides a two-part package and method of use for a pre-attached medical implant and delivery tool system. The package includes a wet compartment and a dry compartment and allows a pre-attached implant and delivery tool system to be at least partially stored immersed in a fluid in the wet compartment and at least partially stored in the dry compartment. In one embodiment the implant comprises a replacement heart valve, and the heart valve is stored inside the wet compartment while the heart valve delivery tool remains dry in the dry compartment. | 09-02-2010 |
20110257735 | SYSTEMS AND METHODS FOR DELIVERING A MEDICAL IMPLANT - The present invention relates to apparatus and methods for endovascularly delivering and releasing a prosthesis, e.g., an aortic prosthesis, within and/or across a patient's native heart valve, referred to hereinafter as replacing the patient's heart valve. In some embodiments the delivery system comprises a plurality of first actuatable element adapted to engage a plurality of second elements in a first configuration to capture the implant within the delivery system, and wherein the plurality of first actuatable element are adapted to engage the plurality of second elements in a second configuration and to release the implant from the delivery system. | 10-20-2011 |
20120016469 | Methods and Apparatus for Endovascularly Replacing a Heart Valve - The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor. | 01-19-2012 |
20120029627 | Methods and Apparatus for Endovascular Heart Valve Replacement Comprising Tissue Grasping Elements - The present invention provides an apparatus for endovascularly replacing a patient's heart valve. In some embodiments, the apparatus includes an expandable anchor supporting a replacement valve, the anchor and replacement valve being adapted for percutaneous delivery and deployment to replace the patient's heart valve, the anchor having a braid having atraumatic grasping elements adapted to grasp tissue in a vicinity of the patient's heart valve. | 02-02-2012 |
20120041550 | Methods and Apparatus for Endovascular Heart Valve Replacement Comprising Tissue Grasping Elements - A method for endovascularly replacing a patient's heart valve including the following steps: endovascularly delivering an anchor and a replacement valve supported within the anchor to a vicinity of the heart valve in a collapsed delivery configuration, the anchor having grasping elements adapted to grasp tissue in a vicinity of the heart valve; expanding the anchor, thereby rotating the grasping elements; and grasping the tissue with the rotating grasping elements. | 02-16-2012 |
20120132547 | TWO-PART PACKAGE FOR MEDICAL IMPLANT - The invention provides a two-part package and method of use for a pre-attached medical implant and delivery tool system. The package includes a wet compartment and a dry compartment and allows a pre-attached implant and delivery tool system to be at least partially stored immersed in a fluid in the wet compartment and at least partially stored in the dry compartment. In one embodiment the implant comprises a replacement heart valve, and the heart valve is stored inside the wet compartment while the heart valve delivery tool remains dry in the dry compartment. | 05-31-2012 |
20130013057 | MEDICAL IMPLANT DEPLOYMENT TOOL - A medical implant deployment tool and deployment method are disclosed. One aspect of the invention provides an implant system including an implant adapted for endovascular delivery and deployment; and a deployment tool adapted to deploy the implant, with the deployment tool having an actuation controller; a plurality of actuation elements adapted to apply forces to one or more implant deployment mechanisms and each adapted to extend along an actuation element path within a patient's vasculature; and an actuation element compensation mechanism adapted to compensate for differences in length between the actuation element paths. | 01-10-2013 |
Patent application number | Description | Published |
20090319023 | Stents and Stent Grafts - The subjected devices include a stent, a graft and a means for attaching the graft to the stent. One or more members are received in a permanent or temporary receptacle within the stent attach the graft to the stent. In one variation, an interference fit is employed; in another, the graft is bonded to a stent-captured member(s). | 12-24-2009 |
20130116778 | Replacement Heart Valve Leaflet Stitching Method and Device - A replacement heart valve and stitching method for reducing the unexpanded profile of the replacement heart valve are herein provided. The method includes whip stitching a plurality of leaflets together with a first whip stitch pattern a second whip stitch pattern which overlaps the first whip stitch pattern and is wound in an opposite direction. The method further involves securing the valve leaflets to one another via a running stitch. | 05-09-2013 |
20140114405 | Medical Devices and Delivery Systems for Delivering Medical Devices - Medical devices and delivery systems for delivering medical devices to a target location within a subject. In some embodiments the medical devices can be locked in a fully deployed and locked configuration. In some embodiments the delivery systems are configured with a single actuator to control the movement of multiple components of the delivery system. In some embodiments the actuator controls the independent and dependent movement of multiple components of the delivery system. | 04-24-2014 |
20140135912 | Methods and Apparatus for Performing Valvuloplasty - The present invention relates to apparatus and methods for performing valvuloplasty. In some embodiments, the apparatus includes an expandable braid valvuloplasty device. In some embodiments, the methods and apparatus may be used as an adjunct to percutaneous heart valve replacement. In some embodiments, the apparatus and methods may provide a medical practitioner with feedback, monitoring or measurement information, e.g., information relevant to percutaneous transcatheter heart valve replacement. | 05-15-2014 |
20140243967 | Methods and Apparatus for Endovascular Heart Valve Replacement Comprising Tissue Grasping Elements - The present invention provides an apparatus for endovascularly replacing a patient's heart valve. In some embodiments, the apparatus includes an expandable anchor supporting a replacement valve, the anchor and replacement valve being adapted for percutaneous delivery and deployment to replace the patient's heart valve, the anchor having a braid having atraumatic grasping elements adapted to grasp tissue in a vicinity of the patient's heart valve. | 08-28-2014 |
20150073540 | METHODS AND APPARATUS FOR ENDOVASCULARLY REPLACING A HEART VALVE - The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor. | 03-12-2015 |
20150127094 | SYSTEMS AND METHODS FOR DELIVERING A MEDICAL IMPLANT - The present invention relates to apparatus and methods for endovascularly delivering and releasing a prosthesis, e.g., an aortic prosthesis, within and/or across a patient's native heart valve, referred to hereinafter as replacing the patient's heart valve. In some embodiments the delivery system comprises a plurality of first actuatable element adapted to engage a plurality of second elements in a first configuration to capture the implant within the delivery system, and wherein the plurality of first actuatable element are adapted to engage the plurality of second elements in a second configuration and to release the implant from the delivery system. | 05-07-2015 |
Patent application number | Description | Published |
20140095459 | SUPPORTING COORDINATED ACCESS TO A FILE SYSTEM'S SHARED STORAGE USING AUTOMATIC ALIGNMENT OF A PARALLEL FILE ACCESS PROTOCOL AND METADATA MANAGEMENT - Embodiments of the invention relate to supporting coordinated access to a file system's shared disk storage subsystem using an automatic alignment of a parallel file access protocol and metadata management on a per object basis. A file server (among servers in the cluster) receives a client's request to access a file stored by the file system in the storage subsystem using a parallel file access protocol. If the file system has selected a file server to serve as a metadata manager of said file, the file server uses the selected file server to coordinate access to the file's metadata. If the file system has not selected a file server to serve as the metadata manager of the file, the file system selects the file server that received said request as the metadata manager for said file until a file close request operation is received. | 04-03-2014 |
20140095544 | COORDINATED ACCESS TO A CLUSTERED FILE SYSTEM'S SHARED STORAGE USING SHARED-LOCK ARCHITECTURE - Embodiments of the invention relate to coordinated access to a clustered file system's shared storage subsystem using a shared-lock architecture. A particular file server is configured to coordinate the file system's file access layout particular server, in response to a client's file access layout request for byte-ranges of a file stored in the storage subsystem being received by a file server in cluster and sent to said particular server, generates a file access layout of a set of file servers for a parallel file access protocol to use and byte ranges of the file that particular individual file servers to use, to service an I/O request for the file. The file server (that received the request), sends the generated file access layout to said client, and requests coordinated access to said file from the particular server in response to receiving an I/O request to byte-ranges of said file. | 04-03-2014 |
20140095582 | COORDINATED ACCESS TO A FILE SYSTEM'S SHARED STORAGE USING DYNAMIC CREATION OF FILE ACCESS LAYOUT - Embodiments of the invention relate to supporting coordinated access to a clustered file system's shared disk storage subsystem by using dynamic creation of file access layout for different workloads and access patterns. Active file servers in the cluster have equivalent access to shared data of said file system. In one embodiment, a particular file server in the cluster is configured to coordinate the file system's layout. The particular file server, in response to a particular client's request for a layout of a file stored by said file system in said subsystem determines a file access layout for a parallel file access protocol to use when servicing an I/O request by said client, marks said layout as active for the client, and sends the layout to the client. The file access layout is determined based on one or more of current file system resources, a specific workload type and a specific byte-range of the file included in the client request, and properties of the file. The layout includes a set of file servers in said cluster and byte ranges of the file, and the byte-range being associated with a particular server among the set. | 04-03-2014 |
20140108732 | CACHE LAYER OPTIMIZATIONS FOR VIRTUALIZED ENVIRONMENTS - Embodiments of the invention relate to optimizing the storage of data in a multi-cache level environment. In one aspect, data is classified into primary and secondary cache sections. Data is differentiated based on an inherent sharing characteristic of the data within a system comprising virtual machines. The data is then placed into the classified sections of the cache storage layer and/or persistent data, reflective of how the data is shared among virtual disk images access by virtual machines. | 04-17-2014 |
Patent application number | Description | Published |
20110078467 | REDUCING ENERGY CONSUMPTION IN A COMPUTING CLUSTER - Embodiments of the invention relate to reducing energy consumption in a computing cluster. An aspect of the invention includes a method for reducing energy consumption in a computing cluster. The method includes monitoring requests to server. The method further includes activating a server, if at least one request is to be routed to the server in a reduced power consumption state. The method further includes routing the requests to at least one server. The method further includes reducing power consumption on the server, if the server does not have at least one active request. | 03-31-2011 |
20110145307 | DIRECTORY TRAVERSAL IN A SCALABLE MULTI-NODE FILE SYSTEM CACHE FOR A REMOTE CLUSTER FILE SYSTEM - Directory traversal in a scalable multi-node file system cache for a remote cluster file system, is provided. One implementation involves maintaining a scalable multi-node file system cache in a local cluster file system, and caching local file data in the cache by fetching file data on demand from a remote cluster file system into the cache over the network. The local file data corresponds to file data in the remote cluster file system. The local namespace emulates the remote namespace and is created on demand. Access to data further involves performing directory traversal for the cache for the remote cluster file system by creating a directory structure on demand. | 06-16-2011 |
20110145363 | DISCONNECTED FILE OPERATIONS IN A SCALABLE MULTI-NODE FILE SYSTEM CACHE FOR A REMOTE CLUSTER FILE SYSTEM - Facilitating access to data in a network, is provided. One implementation involves maintaining a scalable multi-node file system cache in a local cluster file system, and caching file data in a cache by fetching file data on demand from a remote cluster file system into the local cached file system over the network. The local file data corresponds to file data in the remote cluster file system. Upon disconnection from the remote cluster file system, all file operations are supported at the cache. Then, upon reconnection to the remote cluster file system over the network, the remote cluster file system is synchronized with the information cached in the cache during the disconnection even in the presence of failures. | 06-16-2011 |
20110145367 | SCALABLE CACHING OF REMOTE FILE DATA IN A CLUSTER FILE SYSTEM - Scalable caching of remote file data in cluster file systems is provided. One implementation involves maintaining a cache in a local cluster file system and caching local file data in the cache by fetching file data on demand from the remote cluster file system into the local cached file system over the network. The local file data and metadata corresponds to the remote file data and metadata in the remote cluster file system. Updates made to the local file data and metadata are pushed back to the remote cluster file system asynchronously. | 06-16-2011 |
20110145499 | ASYNCHRONOUS FILE OPERATIONS IN A SCALABLE MULTI-NODE FILE SYSTEM CACHE FOR A REMOTE CLUSTER FILE SYSTEM - Asynchronous file operations in a scalable multi-node file system cache for a remote cluster file system, is provided. One implementation involves maintaining a scalable multi-node file system cache in a local cluster file system, and caching local file data in the cache by fetching file data on demand from the remote cluster file system into the cache over the network. The local file data corresponds to file data in the remote cluster file system. Local file information is asynchronously committed from the cache to the remote cluster file system over the network. | 06-16-2011 |
20110296422 | Switch-Aware Parallel File System - Embodiments of the invention related to a switch-aware parallel file system. A computing cluster is partitioned into a plurality of computing cluster building blocks comprising a parallel file system. Each computing cluster building block comprises a file system client, a storage module, a building block metadata module, and a building block network switch. The building block metadata module tracks a storage location of data allocated by the storage module within the computing cluster building block. The computing cluster further comprises a file system metadata module that tracks which of the plurality of computing cluster building blocks data is allocated among within the parallel file system. The computing cluster further comprises a file system network switch to provide the parallel file system with access to each of the plurality of computing cluster building blocks and the file system metadata module. At least one additional computing cluster building block is added to the computing cluster, if resource utilization of the computing cluster exceeds a pre-determined threshold. | 12-01-2011 |
20120278283 | CONSISTENT DATA RETRIEVAL IN A MULTI-SITE COMPUTING INFRASTRUCTURE - Embodiments of the invention relate to dynamic application migration in a shared pool of configurable computer resources with disaster recovery support. Data from an application is replicated from local data storage to remote data storage. A consistency point of the data is created in both the local data storage and the remote data storage. The application may be migrated to a second data site with separate local data storage. The migration may be planned or unplanned. Based upon the created consistency point, a consistent set of application data may be requested to support a read operation from the migrated application. | 11-01-2012 |
20120303686 | SCALABLE CACHING OF REMOTE FILE DATA IN A CLUSTER FILE SYSTEM - Scalable caching of remote file data in cluster file systems is provided. One implementation involves maintaining a cache in a local cluster file system and caching local file data in the cache by fetching file data on demand from the remote cluster file system into the local cached file system over the network. The local file data and metadata corresponds to the remote file data and metadata in the remote cluster file system. Updates made to the local file data and metadata are pushed back to the remote cluster file system asynchronously. | 11-29-2012 |
20120311065 | ASYNCHRONOUS FILE OPERATIONS IN A SCALABLE MULTI-NODE FILE SYSTEM CACHE FOR A REMOTE CLUSTER FILE SYSTEM - Asynchronous file operations in a scalable multi-node file system cache for a remote cluster file system, is provided. One implementation involves maintaining a scalable multi-node file system cache in a local cluster file system, and caching local file data in the cache by fetching file data on demand from the remote cluster file system into the cache over the network. The local file data corresponds to file data in the remote cluster file system. Local file information is asynchronously committed from the cache to the remote cluster file system over the network. | 12-06-2012 |
20120323848 | CONTINUOUS AND ASYNCHRONOUS REPLICATION OF A CONSISTENT DATASET - Embodiments of the invention relate to creating and maintaining consistent data sets in a shared pool of configurable computer resources to support disaster recovery support. Data from an application is stored in local data storage and replicated to another data storage. A consistency point of the data is created in both of the data storage, with the consistency point representing an identical data set at a point-in-time. Based upon the created consistency points, a consistent set of application data may be requested to support a read operation for a migrated application. | 12-20-2012 |
20120323850 | CONTINUOUS AND ASYNCHRONOUS REPLICATION OF A CONSISTENT DATASET - Embodiments of the invention relate to creating and maintaining consistent data sets in a shared pool of configurable computer resources to support disaster recovery support. Data from an application is stored in local data storage and replicated to another data storage. A consistency point of the data is created in both of the data storage, with the consistency point representing an identical data set at a point-in-time. Based upon the created consistency points, a consistent set of application data may be requested to support a read operation for a migrated application. | 12-20-2012 |
20130054808 | MANAGEMENT OF STORAGE CLUSTER PERFORMANCE WITH HYBRID WORKLOADS - Embodiments of the invention relate to management of hybrid workloads, including serial and parallel workload optimizations, in a shared pool of configurable computer resources. Resource utilization in the shared pool is dynamically tracked, and employed for assessing a set of servers a parallel access protocol should utilize for one or more I/O requests in conjunction with any serial workload optimizations. Accordingly, the load balancing embodies a diverse set of workloads to support dynamic and equitable allocation. | 02-28-2013 |
20140173185 | Write Performance in Fault-Tolerant Clustered Storage Systems - Embodiments of the invention relate to supporting transaction data committed to a stable storage. Committed data in the cluster is stored in the persistent cache layer and replicated and stored in the cache layer of one or more secondary nodes. One copy is designated as a master copy and all other copies are designated as replica, with an exclusive write lock assigned to the master and a shared write lock extended to the replica. An acknowledgement of receiving the data is communicated following confirmation that the data has been replicated to each node designated to receive the replica. Managers and a director are provided to support management of the master copy and the replicas within the file system, including invalidation of replicas, fault tolerance associated with failure of a node holding a master copy, recovery from a failed node, recovered of the file system from a power failure, and transferring master and replica copies within the file system. | 06-19-2014 |
20140173326 | Write Performance in Fault-Tolerant Clustered Storage Systems - Embodiments of the invention relate to supporting transaction data committed to a stable storage. Committed data in the cluster is stored in the persistent cache layer and replicated and stored in the cache layer of one or more secondary nodes. One copy is designated as a master copy and all other copies are designated as replica, with an exclusive write lock assigned to the master and a shared write lock extended to the replica. An acknowledgement of receiving the data is communicated following confirmation that the data has been replicated to each node designated to receive the replica. Managers and a director are provided to support management of the master copy and the replicas within the file system, including invalidation of replicas, fault tolerance associated with failure of a node holding a master copy, recovery from a failed node, recovered of the file system from a power failure, and transferring master and replica copies within the file system. | 06-19-2014 |
20140280154 | SCALABLE DATA TRANSFER IN AND OUT OF ANALYTICS CLUSTERS - Embodiments of the invention relate to analytics clusters and to efficiently supporting read and write requests in the cluster. In one aspect, one or more compute nodes within a region of the cluster are designated to support the request, and based upon the designation, the request is directly communicated between a requesting agent external to the cluster and the supporting compute node(s). The direct communication mitigates the functionality of the head node(s) supporting the compute node(s). | 09-18-2014 |
20140280435 | SCALABLE DATA TRANSFER IN AND OUT OF ANALYTICS CLUSTERS - Embodiments of the invention relate to analytics clusters, and to a network layer application to efficiently supporting read and write requests in the cluster. In one aspect, one or more compute nodes within a region of the cluster are designated to support the request, and based upon the designation, the request is directly communicated between a requesting agent external to the cluster and the supporting compute node(s) via a regional hardware element. The direct communication mitigates the functionality of the head node(s) supporting the compute node(s). | 09-18-2014 |
20140280444 | SCALABLE DATA TRANSFER IN AND OUT OF ANALYTICS CLUSTERS - Embodiments of the invention relate to analytics clusters, and to a network layer application to efficiently supporting read and write requests in the cluster. In one aspect, one or more compute nodes within a region of the cluster are designated to support the request, and based upon the designation, the request is directly communicated between a requesting agent external to the cluster and the supporting compute node(s) via a regional hardware element. The direct communication mitigates the functionality of the head node(s) supporting the compute node(s). | 09-18-2014 |
20140280667 | SCALABLE DATA TRANSFER IN AND OUT OF ANALYTICS CLUSTERS - Embodiments of the invention relate to analytics clusters and to efficiently supporting read and write requests in the cluster. In one aspect, one or more compute nodes within a region of the cluster are designated to support the request, and based upon the designation, the request is directly communicated between a requesting agent external to the cluster and the supporting compute node(s). The direct communication mitigates the functionality of the head node(s) supporting the compute node(s). | 09-18-2014 |
20150256432 | MANAGING RESOURCES IN A NETWORKED COMPUTING ENVIRONMENT - An approach for managing and optimizing available resources utilized in a networked computing environment (e.g., a cloud computing environment) is provided. In one aspect, a plurality of resources in a plurality of storage pools within the networked computing environment are monitored. Each storage pool is running at least one application workload using a corresponding subset of the plurality of resources. The storage pools are ranked based on the application workloads. In response to an over-utilized storage pool and/or an under-utilized storage pool, the plurality of resources are dynamically reconfigured. | 09-10-2015 |
20150331925 | Write Performance in Fault-Tolerant Clustered Storage Systems - Embodiments relate to supporting transaction data committed to a stable storage. Committed data in the cluster is stored in the persistent cache layer and replicated and stored in the cache layer of one or more secondary nodes. One copy is designated as a master copy and all other copies are designated as replica, with an exclusive write lock assigned to the master and a shared write lock extended to the replica. An acknowledgement of receiving the data is communicated following confirmation that the data has been replicated to each node designated to receive the replica. Managers and a director are provided to support management of the master copy and the replicas within the file system, including invalidation of replicas, fault tolerance associated with failure of a node holding a master copy, recovery from a failed node, recovered of the file system from a power failure, and transferring master and replica copies within the file system. | 11-19-2015 |
20150350366 | SCALABLE CACHING OF REMOTE FILE DATA IN A CLUSTER FILE SYSTEM - A system facilitates access to data in a network. One implementations includes a caching layer function that is configured to integrate into a local cluster file system, to cache local file data in a cache based on fetching file data on demand from a remote cluster file system, and to operate on a multi-node cache cluster. The cache is visible to file system clients as a Portable Operating System Interface (POSIX) compliant file system, applications execute on the multi-node cache cluster using POSIX semantics via a POSIX compliant file system interface, and data cache is locally consistent for updates made at the multi-node cache cluster using distributed locking for the data cache | 12-03-2015 |
Patent application number | Description | Published |
20150066371 | Integrated Oilfield Decision Making System and Method - A method for acquiring and processing wellbore measurements includes measuring at least one wellbore parameter. The measured wellbore parameters are communicated to a data hub. A computer in signal communication with the data hub automatically processes the measured wellbore parameter using a predefined automatic process. The automatically processed measured wellbore parameter is communicated to at least one user interface based on assigned tasks of a user interacting with the at least one user interface with respect to a wellbore construction procedure. | 03-05-2015 |
20150129306 | Method for Calculating and Displaying Optimized Drilling Operating Parameters and for Characterizing Drilling Performance with Respect to Performance Benchmarks - A method for optimizing drilling includes initializing values of a plurality of drilling operating parameters and drilling response parameters. In a computer, an initial relationship between the plurality of drilling operating parameters and drilling response parameters is determined. A drilling unit to drill a wellbore through subsurface formations. The drilling operating parameters and drilling response parameters are measured during drilling and entered into the computer. A range of values and an optimum value for at least one of the drilling response parameters and at least one of the drilling response parameters is determined in the computer. A display of the at least one of the plurality of drilling operating parameters and the at least one of the drilling response parameters is generated by the computer. | 05-14-2015 |
20150134257 | Automatic Wellbore Condition Indicator and Manager - A method for monitoring condition of a wellbore includes initializing a value of at least one parameter having a relationship to likelihood of a drill string becoming stuck in a wellbore (the HCF). During drilling operations, at least one drilling parameter having a determinable relationship to the HCF is measured. In a computer, the value of the HCF is recalculated based on the at least one measured parameter. The initial value of the HCF and the recalculated values of the HCF are displayed to a user. | 05-14-2015 |
20150134390 | Automatic Wellbore Activity Schedule Adjustment Method and System - A method for scheduling wellbore construction activities includes entering a well plan into a computer. The well plan includes estimated start and stop times for a plurality of activities in a predetermined sequence. Progress of selected ones of the plurality of activities is measured during their performance. In the computer, expected ending time of at least one of the plurality of activities is recalculated based on progress thereof during that activity. In the computer, expected start and stop times are recalculated for each activity subsequent to the activity in progress based on the recalculated expected ending time. The recalculated start and stop times for each subsequent activity are displayed. | 05-14-2015 |
20150142318 | Wellbore Pipe Trip Guidance and Statistical Information Processing Method - A method for optimizing wellbore pipe tripping operation includes entering into a computer parameters related to a maximum safe pipe movement speed within the wellbore along at least one selected depth interval along the wellbore. A maximum safe pipe movement speed is calculated. An actual pipe movement speed is measured along the at least one selected depth interval. In the computer, a display is generated of the measured pipe movement speed along with the maximum safe pipe movement speed over the at least one selected depth interval. | 05-21-2015 |
20150294258 | Method and System for Prioritizing and Allocating Well Operating Tasks - A method for managing well construction operations includes accepting as input to a computer a list of tasks required to complete construction of at least one wellbore, the list of tasks having at least an initial chronological order. Measurements of at least one parameter related to at least one task on the list of tasks is entered into the computer. The list of tasks is prioritized by at least one of changing a chronological order of performance or a length of time to complete at least one of the tasks based on measurements of the at least one parameter. The prioritizing is performed to optimize at least one well construction performance parameter. The prioritized list is displayed to at least one user of the computer. | 10-15-2015 |
Patent application number | Description | Published |
20100096818 | MAGNETO-RHEOLOGICAL DAMPERS FOR SEMI-ACTIVE SUSPENSION SYSTEMS - A magneto-rheological fluid damper includes a damper body having a reservoir for a magneto-rheological fluid, a piston rod, a piston rod guide disposed within the damper body, where the piston rod guide has a passage therein for receiving the piston rod. The magneto-rheological fluid damper further includes at least a first piston rod seal and at least a second piston rod seal arranged to seal between the piston rod guide and the piston rod. The magneto-rheological fluid damper further includes a fluid chamber defined between the piston rod guide and the piston rod, the fluid chamber being in communication with the reservoir. The magneto-rheological fluid damper further includes a piston rod guide filter arranged in a communication path between the fluid chamber and the reservoir to filter particulates out of the magneto-rheological fluid entering the fluid chamber. The magneto-rheological fluid damper further includes an accumulator arranged between the piston rod guide and the damper body. | 04-22-2010 |
20100109276 | CONTROLLABLE VEHICLE SUSPENSION SYSTEM WITH MAGNETO-RHEOLOGICAL FLUID DEVICE - A controllable suspension system for controlling the relative motion between a first body and a second body includes at least one strut including a magneto-rheological fluid damper. The fluid damper includes a piston rod guide disposed within a damper body. The piston rod guide has a passage therein for receiving a piston rod. A piston rod bearing assembly is disposed in the piston rod guide to engage with and support reciprocal motion of the piston rod. At least a first piston rod seal and at least a second piston rod seal are arranged to seal between the piston rod guide and the piston rod. A fluid chamber is defined between the piston rod guide and the piston rod. A piston rod guide gas charged accumulator is arranged between the piston rod and the damper body. | 05-06-2010 |
20110208361 | MOTION CONTROL SYSTEM WITH DIGITAL PROCESSING LINK - A digital processing link for a vibration control system collects sensor signals at a transfer station and combines the sensor signals into a collective signal that is transmitted under a digital communications protocol to a base station. The sensor signals are separated at the base station and individually processed to produce one or more output control signals to actuators for counteracting the measured vibration. | 08-25-2011 |
20150234396 | DEVICES, SYSTEMS, AND METHODS FOR BALANCING CLOSELY COUPLED ROTATING MACHINERY - Devices, systems, and related methods for balancing two or more pieces of independently rotating (e.g., not synchrophased) machinery are provided. In some aspects, the devices, systems, and methods can provide improved balancing techniques and can include providing a controller configured to simultaneously measure/receive vibration data and control balancers, one balancer at a time. In some aspects, the controller can calculate a beating cycle or a beating period using vibration data received from multiple rotating machines. In some aspects, a balance correction command can be derived in part from either one of: (a) an interpolation of an average vibration of the first rotating machine from a complex vibration of the multiple rotating machines or (b) an average vibration derived from one or more rules applied based upon the duration of the beating period or the beating cycle. | 08-20-2015 |
Patent application number | Description | Published |
20090062512 | Comparative ligand mapping from MHC class I positive cells - The present invention relates generally to a methodology for the isolation, purification and identification of peptide ligands presented by MHC positive cells. In particular, the methodology of the present invention relates to the isolation, purification and identification of these peptide ligands from soluble class I and class II MHC molecules which may be from uninfected, infected, or tumorigenic cells. The methodology of the present invention broadly allows for these peptide ligands and their cognate source proteins thereof to be identified and used as markers for infected versus uninfected cells and/or tumorigenic versus nontumorigenic cells, with said identification being useful for marking or targeting a cell for therapeutic treatment or priming the immune response against infected/tumorigenic cells. | 03-05-2009 |
20090182131 | Methods for removing anti-MHC antibodies from a sample - The present invention relates generally to anti-MHC assay methodologies utilizing functionally active, recombinantly produced, and truncated individual soluble MHC trimolecular complexes that are linked to a substrate. The methods include reacting a sample with the substrate having the MHC trimolecular complex linked thereto, whereby antibodies specific for the at least one MHC trimolecular complex linked to the substrate are removed from the biological sample. | 07-16-2009 |
20100003718 | METHOD AND APPARATUS FOR THE PRODUCTION OF SOLUBLE MHC ANTIGENS AND USES THEREOF - The field of the invention relates in general to at least one method and apparatus for the production of soluble MHC antigens and more particularly, but not by way of limitation, to at least one method and apparatus for the production of soluble Class I and II HLA molecules. The field of the invention also includes such produced soluble Class I and II HLA molecules and their use. According to the methodology of the present invention, the soluble Class I and II HLA molecules can be produced from either gDNA or cDNA starting material. | 01-07-2010 |
20100105107 | PURIFICATION AND CHARACTERIZATION OF SOLUBLE MHC PROTEINS - The present invention relates generally to the production and use of functionally active soluble HLA molecules that are isolated and purified substantially away from other proteins, and methods of purifying same. | 04-29-2010 |
20110065587 | EPITOPE TESTING USING SOLUBLE HLA - The present invention relates generally to a methodology for assaying the binding of a peptide to an individual, specific, soluble HLA molecule. | 03-17-2011 |
20110288270 | COMPARATIVE LIGAND MAPPING FROM MHC CLASS I POSITIVE CELLS - The present invention relates generally to a methodology for the isolation, purification and identification of peptide ligands presented by MHC positive cells. In particular, the methodology of the present invention relates to the isolation, purification and identification of these peptide ligands from soluble class I and class II MHC molecules which may be from uninfected, infected, or tumorigenic cells. The methodology of the present invention broadly allows for these peptide ligands and their cognate source proteins thereof to be identified and used as markers for infected versus uninfected cells and/or tumorigenic versus nontumorigenic cells, with said identification being useful for marking or targeting a cell for therapeutic treatment or priming the immune response against infected/tumorigenic cells. | 11-24-2011 |
20120301871 | COMPARATIVE LIGAND MAPPING FROM MHC POSITIVE CELLS - The present invention relates generally to a methodology for the isolation, purification and identification of peptide ligands presented by MHC positive cells. In particular, the methodology of the present invention relates to the isolation, purification and identification of these peptide ligands from soluble class I and class II MHC molecules which may be uninfected, infected, or tumorgenic. The methodology of the present invention broadly allows for these peptide ligands and their comcomittant source proteins thereof to be identified and used as markers for infected versus uninfected cells and/or tumorgenic versus nontumorgenic cells with said identification being useful for marking or targeting a cell for therapeutic treatment or priming the immune response against infected cells. | 11-29-2012 |
20120302452 | COMPARATIVE LIGAND MAPPING FROM MHC CLASS I POSITIVE CELLS - The present invention relates generally to a methodology for the isolation, purification and identification of peptide ligands presented by MHC positive cells. In particular, the methodology of the present invention relates to the isolation, purification and identification of these peptide ligands from soluble class I and class II MHC molecules which may be uninfected, infected, or tumorgenic. The methodology of the present invention broadly allows for these peptide ligands and their comcomittant source proteins thereof to be identified and used as markers for infected versus uninfected cells and/or tumorgenic versus nontumorgenic cells with said identification being useful for marking or targeting a cell for therapeutic treatment or priming the immune response against infected cells. | 11-29-2012 |
20120329080 | ANTI-HLA ASSAY AND METHODS - Anti-MHC assay methodologies utilize functionally active, recombinantly produced, truncated individual soluble MHC trimolecular complexes that are linked to a substrate. | 12-27-2012 |
20120329670 | EPITOPE TESTING USING SOLUBLE HLA - A methodology is provided for assaying the ability of a peptide of interest to displace an endogenously loaded peptide in a recombinantly produced, secreted, individual, soluble HLA trimolecular complex. | 12-27-2012 |
20130131573 | SELECTIVE ANTI-HLA ANTIBODY REMOVAL DEVICE AND METHODS OF PRODUCTION AND USE THEREOF - An anti-MHC removal device includes a serologically active, soluble MHC moiety covalently coupled to a solid support. Methods of production include covalently coupling the serologically active, soluble MHC moiety to the solid support. Methods of use of the anti-MHC removal device include contacting a biological sample with the device so that antibodies specific for the MHC moiety are removed from the biological sample. The biological sample is then recovered. | 05-23-2013 |
20130143235 | COMPARATIVE LIGAND MAPPING FROM MHC CLASS I POSITIVE CELLS - Compositions that include isolated, functionally active, recombinantly produced class I HLA trimolecular complexes that include epitopes unique to breast cancer cells are disclosed. | 06-06-2013 |
20130237689 | SOLUBLE HLA CLASS II COMPLEXES AND METHODS OF PRODUCTION AND USE THEREOF - The production of soluble HLA class II molecules, as well as methods of using the soluble HLA class II molecules so produced, are described herein. | 09-12-2013 |
20130245385 | SELECTIVE ANTI-HLA ANTIBODY REMOVAL DEVICE AND METHODS OF PRODUCTION AND USE THEREOF - An anti-MHC removal device includes a serologically active, soluble MHC moiety covalently coupled to a solid support. Methods of production include covalently coupling the serologically active, soluble MHC moiety to the solid support. Methods of use of the anti-MHC removal device include contacting a biological sample with the device so that antibodies specific for the MHC moiety are removed from the biological sample. | 09-19-2013 |
20140093973 | EPITOPE TESTING USING SOLUBLE HLA - The present invention relates generally to a methodology for assaying the binding of a peptide to an individual, specific, soluble HLA molecule using fluorescence polarization. The peptides utilized in the method may be identified by indirect methods utilizing T lymphocytes, or by a direct method of epitope discovery described herein. | 04-03-2014 |
20150094213 | Comparative Ligand Mapping from MHC Positive Cells - A method of comparative ligand mapping to identify peptide ligands presented by MHC positive cells that distinguish an infected/transfected cell from an uninfected/non-transfected cell is disclosed. | 04-02-2015 |
20150273039 | Compositions Comprising Soluble HLA/M. Tuberculosis-Specific Ligand Complexes and Methods of Production and Use Thereof - Compositions that include at least one isolated, class I HLA trimolecular complex that includes a peptide ligand unique to | 10-01-2015 |